Did Hans Asperger actively assist the Nazi euthanasia program? / Simon BARON-COHEN in Molecular Autism, 9 (2018)  

Public ISBD [article]  inMolecular Autism > 9 (2018) . - 28p. Titre : Did Hans Asperger actively assist the Nazi euthanasia program? Type de document : Texte imprimé et/ou numérique Auteurs : Simon BARON-COHEN, Auteur ; A. KLIN, Auteur ; S. SILBERMAN, Auteur ; Joseph D. BUXBAUM, Auteur Article en page(s) : 28p. Langues : Anglais (eng) Mots-clés : Eugenics  Euthanasia  Humans  National Socialism Index. décimale : PER Périodiques En ligne : https://dx.doi.org/10.1186/s13229-018-0209-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=371 [article] Did Hans Asperger actively assist the Nazi euthanasia program? [Texte imprimé et/ou numérique] / Simon BARON-COHEN, Auteur ; A. KLIN, Auteur ; S. SILBERMAN, Auteur ; Joseph D. BUXBAUM, Auteur . - 28p. Langues : Anglais (eng) in Molecular Autism > 9 (2018) . - 28p. Mots-clés : Eugenics  Euthanasia  Humans  National Socialism Index. décimale : PER Périodiques En ligne : https://dx.doi.org/10.1186/s13229-018-0209-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=371

Early emergence of discrepancy in adaptive behavior and cognitive skills in toddlers with autism spectrum disorder / Jessica BRADSHAW in Autism, 23-6 (August 2019)  

Public ISBD [article]  inAutism > 23-6 (August 2019) . - p.1485-1496 Titre : Early emergence of discrepancy in adaptive behavior and cognitive skills in toddlers with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Jessica BRADSHAW, Auteur ; S. GILLESPIE, Auteur ; C. KLAIMAN, Auteur ; A. KLIN, Auteur ; Celine A. SAULNIER, Auteur Article en page(s) : p.1485-1496 Langues : Anglais (eng) Mots-clés : adaptive behavior  autism spectrum disorders  cognition (attention, learning, and memory)  development Index. décimale : PER Périodiques Résumé : Individuals with autism spectrum disorder and average IQ exhibit a widening discrepancy between lagging adaptive skills relative to their cognitive potential, but it is unknown when this discrepancy emerges in development. To address this important question, we measured adaptive and cognitive skills longitudinally, from 12-36 months, in 96 low-risk typically developing infants and 69 high-risk siblings of children with autism spectrum disorder who at 36 months were diagnosed with autism spectrum disorder (N = 21), the broader autism phenotype (N = 19), or showed no concerns (unaffected; N = 29). Results indicate that both cognitive and adaptive communication skills remained stable over time for all four groups, but toddlers with autism spectrum disorder and the broader autism phenotype failed to keep pace with unaffected and typically developing toddlers with regard to adaptive socialization skills and, to a lesser extent, daily living skills. The odds of having a discrepant developmental profile, with average cognitive skills and below average adaptive skills, was significantly greater for socialization and daily living skills in toddlers with autism spectrum disorder or the broader autism phenotype and increased over time from 12 to 36 months. The discrepancy between adaptive skills and cognition emerges early and widens over time for infants with autism spectrum disorder symptomology, supporting early assessment and intervention of adaptive socialization and daily living skills. En ligne : http://dx.doi.org/10.1177/1362361318815662 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=403 [article] Early emergence of discrepancy in adaptive behavior and cognitive skills in toddlers with autism spectrum disorder [Texte imprimé et/ou numérique] / Jessica BRADSHAW, Auteur ; S. GILLESPIE, Auteur ; C. KLAIMAN, Auteur ; A. KLIN, Auteur ; Celine A. SAULNIER, Auteur . - p.1485-1496. Langues : Anglais (eng) in Autism > 23-6 (August 2019) . - p.1485-1496 Mots-clés : adaptive behavior  autism spectrum disorders  cognition (attention, learning, and memory)  development Index. décimale : PER Périodiques Résumé : Individuals with autism spectrum disorder and average IQ exhibit a widening discrepancy between lagging adaptive skills relative to their cognitive potential, but it is unknown when this discrepancy emerges in development. To address this important question, we measured adaptive and cognitive skills longitudinally, from 12-36 months, in 96 low-risk typically developing infants and 69 high-risk siblings of children with autism spectrum disorder who at 36 months were diagnosed with autism spectrum disorder (N = 21), the broader autism phenotype (N = 19), or showed no concerns (unaffected; N = 29). Results indicate that both cognitive and adaptive communication skills remained stable over time for all four groups, but toddlers with autism spectrum disorder and the broader autism phenotype failed to keep pace with unaffected and typically developing toddlers with regard to adaptive socialization skills and, to a lesser extent, daily living skills. The odds of having a discrepant developmental profile, with average cognitive skills and below average adaptive skills, was significantly greater for socialization and daily living skills in toddlers with autism spectrum disorder or the broader autism phenotype and increased over time from 12 to 36 months. The discrepancy between adaptive skills and cognition emerges early and widens over time for infants with autism spectrum disorder symptomology, supporting early assessment and intervention of adaptive socialization and daily living skills. En ligne : http://dx.doi.org/10.1177/1362361318815662 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=403

In Memoriam: Domenic V. Cicchetti, PhD. 1937-2019 / Roald A. ØIEN in Journal of Autism and Developmental Disorders, 49-9 (September 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-9 (September 2019) . - p.3475-3476 Titre : In Memoriam: Domenic V. Cicchetti, PhD. 1937-2019 Type de document : Texte imprimé et/ou numérique Auteurs : Roald A. ØIEN, Auteur ; A. KLIN, Auteur ; Celine A. SAULNIER, Auteur ; Katarzyna CHAWARSKA, Auteur ; J. C. MCPARTLAND, Auteur ; Anders NORDAHL-HANSEN, Auteur ; Fred R. VOLKMAR, Auteur Article en page(s) : p.3475-3476 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-019-04143-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=405 [article] In Memoriam: Domenic V. Cicchetti, PhD. 1937-2019 [Texte imprimé et/ou numérique] / Roald A. ØIEN, Auteur ; A. KLIN, Auteur ; Celine A. SAULNIER, Auteur ; Katarzyna CHAWARSKA, Auteur ; J. C. MCPARTLAND, Auteur ; Anders NORDAHL-HANSEN, Auteur ; Fred R. VOLKMAR, Auteur . - p.3475-3476. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-9 (September 2019) . - p.3475-3476 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-019-04143-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=405

Research Review: Outcomes of 24- to 36-month-old children with autism spectrum disorder vary by ascertainment strategy: a systematic review and meta-analysis / M. MICHELETTI in Journal of Child Psychology and Psychiatry, 61-1 (January 2020)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 61-1 (January 2020) . - p.4-17 Titre : Research Review: Outcomes of 24- to 36-month-old children with autism spectrum disorder vary by ascertainment strategy: a systematic review and meta-analysis Type de document : Texte imprimé et/ou numérique Auteurs : M. MICHELETTI, Auteur ; C. MCCRACKEN, Auteur ; John N. CONSTANTINO, Auteur ; D. MANDELL, Auteur ; W. JONES, Auteur ; A. KLIN, Auteur Article en page(s) : p.4-17 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  meta-analysis  outcomes  sampling bias  surveillance  systematic review  toddlers Index. décimale : PER Périodiques Résumé : BACKGROUND: Despite widespread recommendations for early surveillance of risk for autism spectrum disorder (ASD), no research to date has shown that early surveillance leads to better clinical outcomes. Preliminary research has suggested that children with ASD ascertained via prospective follow-up have better outcomes than those ascertained via community referral. Because prospective studies include early surveillance, by comparing outcomes of children with ASD across ascertainment strategies, we may gain insight into the effects of early surveillance relative to its absence. METHODS: A systematic review was conducted to identify studies reporting outcomes of 24- to 36-month-olds with ASD ascertained via prospective follow-up, community referral, or universal screening. A meta-analysis using a random effects model was used to calculate overall effect size estimates for developmental level and symptom severity across ascertainment cohorts. RESULTS: Eleven prospective, ten community referral, and eight universal screening studies were identified, reporting on 1,658 toddlers with ASD. We found no differences in outcomes between community referral and universal screening studies. Relative to both, prospective studies reported significantly higher developmental levels and lower symptom severities. CONCLUSIONS: Outcomes of young children with ASD ascertained via prospective follow-up are better than those of children with ASD recruited via community referral or universal screening. Although we discuss why sampling bias is not likely the driving force behind these findings, we cannot rule out the possibility that sampling bias contributes to the observed differences; future studies should probe the effects of sociodemographic variables on clinical outcomes as a function of ascertainment strategy. This limitation notwithstanding, our results raise the possibility that prospective follow-up may confer a 'surveillance effect' that contributes to improved developmental and diagnostic outcomes in children with ASD. Future research should test this hypothesis and determine the specific mechanism by which surveillance may improve outcomes. En ligne : http://dx.doi.org/10.1111/jcpp.13057 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 [article] Research Review: Outcomes of 24- to 36-month-old children with autism spectrum disorder vary by ascertainment strategy: a systematic review and meta-analysis [Texte imprimé et/ou numérique] / M. MICHELETTI, Auteur ; C. MCCRACKEN, Auteur ; John N. CONSTANTINO, Auteur ; D. MANDELL, Auteur ; W. JONES, Auteur ; A. KLIN, Auteur . - p.4-17. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 61-1 (January 2020) . - p.4-17 Mots-clés : Autism spectrum disorder  meta-analysis  outcomes  sampling bias  surveillance  systematic review  toddlers Index. décimale : PER Périodiques Résumé : BACKGROUND: Despite widespread recommendations for early surveillance of risk for autism spectrum disorder (ASD), no research to date has shown that early surveillance leads to better clinical outcomes. Preliminary research has suggested that children with ASD ascertained via prospective follow-up have better outcomes than those ascertained via community referral. Because prospective studies include early surveillance, by comparing outcomes of children with ASD across ascertainment strategies, we may gain insight into the effects of early surveillance relative to its absence. METHODS: A systematic review was conducted to identify studies reporting outcomes of 24- to 36-month-olds with ASD ascertained via prospective follow-up, community referral, or universal screening. A meta-analysis using a random effects model was used to calculate overall effect size estimates for developmental level and symptom severity across ascertainment cohorts. RESULTS: Eleven prospective, ten community referral, and eight universal screening studies were identified, reporting on 1,658 toddlers with ASD. We found no differences in outcomes between community referral and universal screening studies. Relative to both, prospective studies reported significantly higher developmental levels and lower symptom severities. CONCLUSIONS: Outcomes of young children with ASD ascertained via prospective follow-up are better than those of children with ASD recruited via community referral or universal screening. Although we discuss why sampling bias is not likely the driving force behind these findings, we cannot rule out the possibility that sampling bias contributes to the observed differences; future studies should probe the effects of sociodemographic variables on clinical outcomes as a function of ascertainment strategy. This limitation notwithstanding, our results raise the possibility that prospective follow-up may confer a 'surveillance effect' that contributes to improved developmental and diagnostic outcomes in children with ASD. Future research should test this hypothesis and determine the specific mechanism by which surveillance may improve outcomes. En ligne : http://dx.doi.org/10.1111/jcpp.13057 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413

Visual Traces of Language Acquisition in Toddlers with Autism Spectrum Disorder During the Second Year of Life / Serene HABAYEB in Journal of Autism and Developmental Disorders, 51-7 (July 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-7 (July 2021) . - p.2519-2530 Titre : Visual Traces of Language Acquisition in Toddlers with Autism Spectrum Disorder During the Second Year of Life Type de document : Texte imprimé et/ou numérique Auteurs : Serene HABAYEB, Auteur ; T. TSANG, Auteur ; Celine A. SAULNIER, Auteur ; C. KLAIMAN, Auteur ; W. JONES, Auteur ; A. KLIN, Auteur ; L. A. EDWARDS, Auteur Article en page(s) : p.2519-2530 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/complications  Child Development  Child, Preschool  Cross-Sectional Studies  Eye Movements  Face  Humans  Infant  Language  Language Development  Male  Visual Perception  Autism spectrum disorder  Eye-tracking  Heterogeneity  Infant development  Language acquisition  Social visual engagement Index. décimale : PER Périodiques Résumé : Infants show shifting patterns of visual engagement to faces over the first years of life. To explore the adaptive implications of this engagement, we collected eye-tracking measures on cross-sectional samples of 10-25-month-old typically developing toddlers (TD;N?=?28) and those with autism spectrum disorder (ASD;N?=?54). Concurrent language assessments were conducted and relationships between visual engagement and expressive and receptive language were analyzed between groups, and within ASD subgroups. TD and ASD toddlers exhibited greater mouth- than eye-looking, with TD exhibiting higher levels of mouth-looking than ASD. Mouth-looking was positively associated with expressive language in TD toddlers, and in ASD toddlers who had acquired first words. Mouth-looking was unrelated to expressive language in ASD toddlers who had not yet acquired first words. En ligne : http://dx.doi.org/10.1007/s10803-020-04730-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452 [article] Visual Traces of Language Acquisition in Toddlers with Autism Spectrum Disorder During the Second Year of Life [Texte imprimé et/ou numérique] / Serene HABAYEB, Auteur ; T. TSANG, Auteur ; Celine A. SAULNIER, Auteur ; C. KLAIMAN, Auteur ; W. JONES, Auteur ; A. KLIN, Auteur ; L. A. EDWARDS, Auteur . - p.2519-2530. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-7 (July 2021) . - p.2519-2530 Mots-clés : Autism Spectrum Disorder/complications  Child Development  Child, Preschool  Cross-Sectional Studies  Eye Movements  Face  Humans  Infant  Language  Language Development  Male  Visual Perception  Autism spectrum disorder  Eye-tracking  Heterogeneity  Infant development  Language acquisition  Social visual engagement Index. décimale : PER Périodiques Résumé : Infants show shifting patterns of visual engagement to faces over the first years of life. To explore the adaptive implications of this engagement, we collected eye-tracking measures on cross-sectional samples of 10-25-month-old typically developing toddlers (TD;N?=?28) and those with autism spectrum disorder (ASD;N?=?54). Concurrent language assessments were conducted and relationships between visual engagement and expressive and receptive language were analyzed between groups, and within ASD subgroups. TD and ASD toddlers exhibited greater mouth- than eye-looking, with TD exhibiting higher levels of mouth-looking than ASD. Mouth-looking was positively associated with expressive language in TD toddlers, and in ASD toddlers who had acquired first words. Mouth-looking was unrelated to expressive language in ASD toddlers who had not yet acquired first words. En ligne : http://dx.doi.org/10.1007/s10803-020-04730-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452

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