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Détail de l'auteur
Auteur Lauren KENWORTHY |
Documents disponibles écrits par cet auteur (25)
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Neural Basis of Visual Attentional Orienting in Childhood Autism Spectrum Disorders / Eric R. MURPHY in Journal of Autism and Developmental Disorders, 47-1 (January 2017)
[article]
Titre : Neural Basis of Visual Attentional Orienting in Childhood Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Eric R. MURPHY, Auteur ; Megan NORR, Auteur ; John F. STRANG, Auteur ; Lauren KENWORTHY, Auteur ; William D. GAILLARD, Auteur ; Chandan J. VAIDYA, Auteur Article en page(s) : p.58-67 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Attention orienting Visual salience fMRI Restricted and repetitive behavior Index. décimale : PER Périodiques Résumé : We examined spontaneous attention orienting to visual salience in stimuli without social significance using a modified Dot-Probe task during functional magnetic resonance imaging in high-functioning preadolescent children with Autism Spectrum Disorder (ASD) and age- and IQ-matched control children. While the magnitude of attentional bias (faster response to probes in the location of solid color patch) to visually salient stimuli was similar in the groups, activation differences in frontal and temporoparietal regions suggested hyper-sensitivity to visual salience or to sameness in ASD children. Further, activation in a subset of those regions was associated with symptoms of restricted and repetitive behavior. Thus, atypicalities in response to visual properties of stimuli may drive attentional orienting problems associated with ASD. En ligne : http://dx.doi.org/10.1007/s10803-016-2928-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298
in Journal of Autism and Developmental Disorders > 47-1 (January 2017) . - p.58-67[article] Neural Basis of Visual Attentional Orienting in Childhood Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Eric R. MURPHY, Auteur ; Megan NORR, Auteur ; John F. STRANG, Auteur ; Lauren KENWORTHY, Auteur ; William D. GAILLARD, Auteur ; Chandan J. VAIDYA, Auteur . - p.58-67.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 47-1 (January 2017) . - p.58-67
Mots-clés : Autism spectrum disorder Attention orienting Visual salience fMRI Restricted and repetitive behavior Index. décimale : PER Périodiques Résumé : We examined spontaneous attention orienting to visual salience in stimuli without social significance using a modified Dot-Probe task during functional magnetic resonance imaging in high-functioning preadolescent children with Autism Spectrum Disorder (ASD) and age- and IQ-matched control children. While the magnitude of attentional bias (faster response to probes in the location of solid color patch) to visually salient stimuli was similar in the groups, activation differences in frontal and temporoparietal regions suggested hyper-sensitivity to visual salience or to sameness in ASD children. Further, activation in a subset of those regions was associated with symptoms of restricted and repetitive behavior. Thus, atypicalities in response to visual properties of stimuli may drive attentional orienting problems associated with ASD. En ligne : http://dx.doi.org/10.1007/s10803-016-2928-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298 Neural Correlates of Set-Shifting in Children With Autism / Benjamin E. YERYS in Autism Research, 8-4 (August 2015)
[article]
Titre : Neural Correlates of Set-Shifting in Children With Autism Type de document : Texte imprimé et/ou numérique Auteurs : Benjamin E. YERYS, Auteur ; Ligia ANTEZANA, Auteur ; Rachel WEINBLATT, Auteur ; Kathryn F. JANKOWSKI, Auteur ; John STRANG, Auteur ; Chandan J. VAIDYA, Auteur ; Robert T. SCHULTZ, Auteur ; William D. GAILLARD, Auteur ; Lauren KENWORTHY, Auteur Article en page(s) : p.386-397 Langues : Anglais (eng) Mots-clés : autism cognitive control set-shifting functional magnetic resonance imaging cingulate prefrontal cortex Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is often associated with high levels of inflexible thinking and rigid behavior. The neural correlates of these behaviors have been investigated in adults and older adolescents, but not children. Prior studies utilized set-shifting tasks that engaged multiple levels of shifting, and depended on learning abstract rules and establishing a strong prepotent bias. These additional demands complicate simple interpretations of the results. We used functional magnetic resonance imaging (fMRI) to investigate the neural correlates of set-shifting in 20 children (ages 7–14) with ASD and 19 typically developing, matched, control children. Participants completed a set-shifting task that minimized nonshifting task demands through the use of concrete instructions that provide spatial mapping of stimuli-responses. The shift/stay sets were given an equal number of trials to limit the prepotent bias. Both groups showed an equivalent “switch cost,” responding less accurately and slower to Switch stimuli than Stay stimuli, although the ASD group was less accurate overall. Both groups showed activation in prefrontal, striatal, parietal, and cerebellum regions known to govern effective set-shifts. Compared to controls, children with ASD demonstrated decreased activation of the right middle temporal gyrus across all trials, but increased activation in the mid-dorsal cingulate cortex/superior frontal gyrus, left middle frontal, and right inferior frontal gyri during the Switch vs. Stay contrast. The successful behavioral switching performance of children with ASD comes at the cost of requiring greater engagement of frontal regions, suggesting less efficiency at this lowest level of shifting. Autism Res 2015, 8: 386–397. © 2015 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1454 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=268
in Autism Research > 8-4 (August 2015) . - p.386-397[article] Neural Correlates of Set-Shifting in Children With Autism [Texte imprimé et/ou numérique] / Benjamin E. YERYS, Auteur ; Ligia ANTEZANA, Auteur ; Rachel WEINBLATT, Auteur ; Kathryn F. JANKOWSKI, Auteur ; John STRANG, Auteur ; Chandan J. VAIDYA, Auteur ; Robert T. SCHULTZ, Auteur ; William D. GAILLARD, Auteur ; Lauren KENWORTHY, Auteur . - p.386-397.
Langues : Anglais (eng)
in Autism Research > 8-4 (August 2015) . - p.386-397
Mots-clés : autism cognitive control set-shifting functional magnetic resonance imaging cingulate prefrontal cortex Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is often associated with high levels of inflexible thinking and rigid behavior. The neural correlates of these behaviors have been investigated in adults and older adolescents, but not children. Prior studies utilized set-shifting tasks that engaged multiple levels of shifting, and depended on learning abstract rules and establishing a strong prepotent bias. These additional demands complicate simple interpretations of the results. We used functional magnetic resonance imaging (fMRI) to investigate the neural correlates of set-shifting in 20 children (ages 7–14) with ASD and 19 typically developing, matched, control children. Participants completed a set-shifting task that minimized nonshifting task demands through the use of concrete instructions that provide spatial mapping of stimuli-responses. The shift/stay sets were given an equal number of trials to limit the prepotent bias. Both groups showed an equivalent “switch cost,” responding less accurately and slower to Switch stimuli than Stay stimuli, although the ASD group was less accurate overall. Both groups showed activation in prefrontal, striatal, parietal, and cerebellum regions known to govern effective set-shifts. Compared to controls, children with ASD demonstrated decreased activation of the right middle temporal gyrus across all trials, but increased activation in the mid-dorsal cingulate cortex/superior frontal gyrus, left middle frontal, and right inferior frontal gyri during the Switch vs. Stay contrast. The successful behavioral switching performance of children with ASD comes at the cost of requiring greater engagement of frontal regions, suggesting less efficiency at this lowest level of shifting. Autism Res 2015, 8: 386–397. © 2015 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1454 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=268 A preliminary study of self-reported food selectivity in adolescents and young adults with autism spectrum disorder / Emily S. KUSCHNER in Research in Autism Spectrum Disorders, 15-16 (July 2015)
[article]
Titre : A preliminary study of self-reported food selectivity in adolescents and young adults with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Emily S. KUSCHNER, Auteur ; Ian W. EISENBERG, Auteur ; Bako ORIONZI, Auteur ; W. Kyle SIMMONS, Auteur ; Lauren KENWORTHY, Auteur ; Alex MARTIN, Auteur ; Gregory L. WALLACE, Auteur Article en page(s) : p.53-59 Langues : Anglais (eng) Mots-clés : Autism Food Taste Sensory Adolescent Adult Index. décimale : PER Périodiques Résumé : Although it is well-established that picky eating is a common feature of early development in autism spectrum disorder (ASD), far less is known about food selectivity during adolescence and adulthood. Using portions of the Adult/Adolescent Sensory Profile, food selectivity self-ratings were obtained from 65 high-functioning adolescents/young adults with ASD and compared to those of 59 typically developing controls matched on age, IQ, and sex ratio. Individuals with ASD reported preferring familiar foods (food neophobia) and disliking foods with particular textures and strong flavors. Providing linkage to everyday behavior, parent ratings of daily living skills were lower among individuals with ASD and food neophobia than among those without food neophobia. Food selectivity continues to be an important issue for adolescents/young adults with ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2015.04.005 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=261
in Research in Autism Spectrum Disorders > 15-16 (July 2015) . - p.53-59[article] A preliminary study of self-reported food selectivity in adolescents and young adults with autism spectrum disorder [Texte imprimé et/ou numérique] / Emily S. KUSCHNER, Auteur ; Ian W. EISENBERG, Auteur ; Bako ORIONZI, Auteur ; W. Kyle SIMMONS, Auteur ; Lauren KENWORTHY, Auteur ; Alex MARTIN, Auteur ; Gregory L. WALLACE, Auteur . - p.53-59.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 15-16 (July 2015) . - p.53-59
Mots-clés : Autism Food Taste Sensory Adolescent Adult Index. décimale : PER Périodiques Résumé : Although it is well-established that picky eating is a common feature of early development in autism spectrum disorder (ASD), far less is known about food selectivity during adolescence and adulthood. Using portions of the Adult/Adolescent Sensory Profile, food selectivity self-ratings were obtained from 65 high-functioning adolescents/young adults with ASD and compared to those of 59 typically developing controls matched on age, IQ, and sex ratio. Individuals with ASD reported preferring familiar foods (food neophobia) and disliking foods with particular textures and strong flavors. Providing linkage to everyday behavior, parent ratings of daily living skills were lower among individuals with ASD and food neophobia than among those without food neophobia. Food selectivity continues to be an important issue for adolescents/young adults with ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2015.04.005 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=261 Real-World Executive Functions in Adults with Autism Spectrum Disorder: Profiles of Impairment and Associations with Adaptive Functioning and Co-morbid Anxiety and Depression / Gregory L. WALLACE in Journal of Autism and Developmental Disorders, 46-3 (March 2016)
[article]
Titre : Real-World Executive Functions in Adults with Autism Spectrum Disorder: Profiles of Impairment and Associations with Adaptive Functioning and Co-morbid Anxiety and Depression Type de document : Texte imprimé et/ou numérique Auteurs : Gregory L. WALLACE, Auteur ; Lauren KENWORTHY, Auteur ; Cara E. PUGLIESE, Auteur ; Haroon S. POPAL, Auteur ; Emily I. WHITE, Auteur ; Emily BRODSKY, Auteur ; Alex MARTIN, Auteur Article en page(s) : p.1071-1083 Langues : Anglais (eng) Mots-clés : Autism Adult Executive function Adaptive functioning Anxiety Depression Index. décimale : PER Périodiques Résumé : Although executive functioning (EF) difficulties are well documented among children and adolescents with autism spectrum disorder (ASD), little is known about real-world measures of EF among adults with ASD. Therefore, this study examined parent-reported real-world EF problems among 35 adults with ASD without intellectual disability and their correlations with adaptive functioning and co-morbid anxiety and depression symptomatology. A variable EF profile was found with prominent deficits occurring in flexibility and metacognition. Flexibility problems were associated with anxiety-related symptoms while metacognition difficulties were associated with depression symptoms and impaired adaptive functioning (though the metacognition-adaptive functioning relationship was moderated by ADHD symptoms). These persistent EF problems are predictors of broader functioning and therefore remain an important treatment target among adults with ASD. En ligne : http://dx.doi.org/10.1007/s10803-015-2655-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=281
in Journal of Autism and Developmental Disorders > 46-3 (March 2016) . - p.1071-1083[article] Real-World Executive Functions in Adults with Autism Spectrum Disorder: Profiles of Impairment and Associations with Adaptive Functioning and Co-morbid Anxiety and Depression [Texte imprimé et/ou numérique] / Gregory L. WALLACE, Auteur ; Lauren KENWORTHY, Auteur ; Cara E. PUGLIESE, Auteur ; Haroon S. POPAL, Auteur ; Emily I. WHITE, Auteur ; Emily BRODSKY, Auteur ; Alex MARTIN, Auteur . - p.1071-1083.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 46-3 (March 2016) . - p.1071-1083
Mots-clés : Autism Adult Executive function Adaptive functioning Anxiety Depression Index. décimale : PER Périodiques Résumé : Although executive functioning (EF) difficulties are well documented among children and adolescents with autism spectrum disorder (ASD), little is known about real-world measures of EF among adults with ASD. Therefore, this study examined parent-reported real-world EF problems among 35 adults with ASD without intellectual disability and their correlations with adaptive functioning and co-morbid anxiety and depression symptomatology. A variable EF profile was found with prominent deficits occurring in flexibility and metacognition. Flexibility problems were associated with anxiety-related symptoms while metacognition difficulties were associated with depression symptoms and impaired adaptive functioning (though the metacognition-adaptive functioning relationship was moderated by ADHD symptoms). These persistent EF problems are predictors of broader functioning and therefore remain an important treatment target among adults with ASD. En ligne : http://dx.doi.org/10.1007/s10803-015-2655-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=281 Replication and Comparison of the Newly Proposed ADOS-2, Module 4 Algorithm in ASD Without ID: A Multi-site Study / Cara E. PUGLIESE in Journal of Autism and Developmental Disorders, 45-12 (December 2015)
[article]
Titre : Replication and Comparison of the Newly Proposed ADOS-2, Module 4 Algorithm in ASD Without ID: A Multi-site Study Type de document : Texte imprimé et/ou numérique Auteurs : Cara E. PUGLIESE, Auteur ; Lauren KENWORTHY, Auteur ; Vanessa H. BAL, Auteur ; Gregory L. WALLACE, Auteur ; Benjamin E. YERYS, Auteur ; Brenna B. MADDOX, Auteur ; Susan W. WHITE, Auteur ; Haroon POPAL, Auteur ; Anna Chelsea ARMOUR, Auteur ; Judith MILLER, Auteur ; John D. HERRINGTON, Auteur ; Robert T. SCHULTZ, Auteur ; Alex MARTIN, Auteur ; Laura GUTERMUTH ANTHONY, Auteur Année de publication : 2015 Article en page(s) : p.3919-3931 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Adults Adolescents Diagnosis Autism diagnostic observation schedule Sensitivity Specificity Index. décimale : PER Périodiques Résumé : Recent updates have been proposed to the Autism Diagnostic Observation Schedule-2 Module 4 diagnostic algorithm. This new algorithm, however, has not yet been validated in an independent sample without intellectual disability (ID). This multi-site study compared the original and revised algorithms in individuals with ASD without ID. The revised algorithm demonstrated increased sensitivity, but lower specificity in the overall sample. Estimates were highest for females, individuals with a verbal IQ below 85 or above 115, and ages 16 and older. Best practice diagnostic procedures should include the Module 4 in conjunction with other assessment tools. Balancing needs for sensitivity and specificity depending on the purpose of assessment (e.g., clinical vs. research) and demographic characteristics mentioned above will enhance its utility. En ligne : http://dx.doi.org/10.1007/s10803-015-2586-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=273
in Journal of Autism and Developmental Disorders > 45-12 (December 2015) . - p.3919-3931[article] Replication and Comparison of the Newly Proposed ADOS-2, Module 4 Algorithm in ASD Without ID: A Multi-site Study [Texte imprimé et/ou numérique] / Cara E. PUGLIESE, Auteur ; Lauren KENWORTHY, Auteur ; Vanessa H. BAL, Auteur ; Gregory L. WALLACE, Auteur ; Benjamin E. YERYS, Auteur ; Brenna B. MADDOX, Auteur ; Susan W. WHITE, Auteur ; Haroon POPAL, Auteur ; Anna Chelsea ARMOUR, Auteur ; Judith MILLER, Auteur ; John D. HERRINGTON, Auteur ; Robert T. SCHULTZ, Auteur ; Alex MARTIN, Auteur ; Laura GUTERMUTH ANTHONY, Auteur . - 2015 . - p.3919-3931.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 45-12 (December 2015) . - p.3919-3931
Mots-clés : Autism spectrum disorder Adults Adolescents Diagnosis Autism diagnostic observation schedule Sensitivity Specificity Index. décimale : PER Périodiques Résumé : Recent updates have been proposed to the Autism Diagnostic Observation Schedule-2 Module 4 diagnostic algorithm. This new algorithm, however, has not yet been validated in an independent sample without intellectual disability (ID). This multi-site study compared the original and revised algorithms in individuals with ASD without ID. The revised algorithm demonstrated increased sensitivity, but lower specificity in the overall sample. Estimates were highest for females, individuals with a verbal IQ below 85 or above 115, and ages 16 and older. Best practice diagnostic procedures should include the Module 4 in conjunction with other assessment tools. Balancing needs for sensitivity and specificity depending on the purpose of assessment (e.g., clinical vs. research) and demographic characteristics mentioned above will enhance its utility. En ligne : http://dx.doi.org/10.1007/s10803-015-2586-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=273 Sex differences in parent-reported executive functioning and adaptive behavior in children and young adults with autism spectrum disorder / Emily I. WHITE in Autism Research, 10-10 (October 2017)
PermalinkSocial analogical reasoning in school-aged children with autism spectrum disorder and typically developing peers / Adam E. GREEN in Autism, 21-4 (May 2017)
PermalinkSolving Executive Function Challenges / Lauren KENWORTHY
PermalinkStill Left Behind: Fewer Black School-Aged Youth Receive ASD Diagnoses Compared to White Youth / Serene HABAYEB in Journal of Autism and Developmental Disorders, 52-5 (May 2022)
PermalinkThe Flexibility Scale: Development and Preliminary Validation of a Cognitive Flexibility Measure in Children with Autism Spectrum Disorders / John F. STRANG in Journal of Autism and Developmental Disorders, 47-8 (August 2017)
PermalinkThe Gap Between Adaptive Behavior and Intelligence in Autism Persists into Young Adulthood and is Linked to Psychiatric Co-morbidities / Catherine K. KRAPER in Journal of Autism and Developmental Disorders, 47-10 (October 2017)
PermalinkUnstuck and On Target! An Executive Function Curriculum to Improve Flexibility for Children with Autism Spectrum Disorders / Lynn R. CANNON
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