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Mention de date : December 2020
Paru le : 01/12/2020 |
[n° ou bulletin]
[n° ou bulletin]
61-12 - December 2020 [Texte imprimé et/ou numérique] . - 2020. Langues : Anglais (eng)
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Dépouillements


Editorial: Biomarkers in precision medicine for mental illnesses / Bradley S. PETERSON in Journal of Child Psychology and Psychiatry, 61-12 (December 2020)
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Titre : Editorial: Biomarkers in precision medicine for mental illnesses Type de document : Texte imprimé et/ou numérique Auteurs : Bradley S. PETERSON, Auteur Article en page(s) : p.1279-1281 Langues : Anglais (eng) Mots-clés : Precision medicine biomarkers endophenotype mental illness personalized medicine prediction public health treatment validation Index. décimale : PER Périodiques Résumé : Precision medicine and biomarker development have become the prevailing paradigm for mental health research. Despite its conceptual elegance and dominance as a research framework, precision medicine has a very limited track record of demonstrable success thus far for mental illnesses, due in varying degrees to the complexity of both the brain and the pathophysiology of mental illnesses, which limits our ability to develop, replicate, and validate biomarkers for use in enhancing clinical care for mental illnesses, especially in high-risk and complex clinical populations. Research and funding priorities should integrate biomarker development and precision medicine interventions that target the robust behavioral, environmental, and social determinants that we know are important for population-based mental health. En ligne : http://dx.doi.org/10.1111/jcpp.13357 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1279-1281[article] Editorial: Biomarkers in precision medicine for mental illnesses [Texte imprimé et/ou numérique] / Bradley S. PETERSON, Auteur . - p.1279-1281.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1279-1281
Mots-clés : Precision medicine biomarkers endophenotype mental illness personalized medicine prediction public health treatment validation Index. décimale : PER Périodiques Résumé : Precision medicine and biomarker development have become the prevailing paradigm for mental health research. Despite its conceptual elegance and dominance as a research framework, precision medicine has a very limited track record of demonstrable success thus far for mental illnesses, due in varying degrees to the complexity of both the brain and the pathophysiology of mental illnesses, which limits our ability to develop, replicate, and validate biomarkers for use in enhancing clinical care for mental illnesses, especially in high-risk and complex clinical populations. Research and funding priorities should integrate biomarker development and precision medicine interventions that target the robust behavioral, environmental, and social determinants that we know are important for population-based mental health. En ligne : http://dx.doi.org/10.1111/jcpp.13357 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 Research Review: Brain network connectivity and the heterogeneity of depression in adolescence - a precision mental health perspective / Rajpreet CHAHAL in Journal of Child Psychology and Psychiatry, 61-12 (December 2020)
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Titre : Research Review: Brain network connectivity and the heterogeneity of depression in adolescence - a precision mental health perspective Type de document : Texte imprimé et/ou numérique Auteurs : Rajpreet CHAHAL, Auteur ; Ian H. GOTLIB, Auteur ; Amanda E. GUYER, Auteur Article en page(s) : p.1282-1298 Langues : Anglais (eng) Mots-clés : Depression adolescence brain networks connectivity heterogeneity precision mental health Index. décimale : PER Périodiques Résumé : BACKGROUND: Adolescence is a period of high risk for the onset of depression, characterized by variability in symptoms, severity, and course. During adolescence, the neurocircuitry implicated in depression continues to mature, suggesting that it is an important period for intervention. Reflecting the recent emergence of 'precision mental health' - a person-centered approach to identifying, preventing, and treating psychopathology - researchers have begun to document associations between heterogeneity in features of depression and individual differences in brain circuitry, most frequently in resting-state functional connectivity (RSFC). METHODS: In this review, we present emerging work examining pre- and post-treatment measures of network connectivity in depressed adolescents; these studies reveal potential intervention-specific neural markers of treatment efficacy. We also review findings from studies examining associations between network connectivity and both types of depressive symptoms and response to treatment in adults, and indicate how this work can be extended to depressed adolescents. Finally, we offer recommendations for research that we believe will advance the science of precision mental health of adolescence. RESULTS: Nascent studies suggest that linking RSFC-based pathophysiological variation with effects of different types of treatment and changes in mood following specific interventions will strengthen predictions of prognosis and treatment response. Studies with larger sample sizes and direct comparisons of treatments are required to determine whether RSFC patterns are reliable neuromarkers of treatment response for depressed adolescents. Although we are not yet at the point of using RSFC to guide clinical decision-making, findings from research examining the stability and reliability of RSFC point to a favorable future for network-based clinical phenotyping. CONCLUSIONS: Delineating the correspondence between specific clinical characteristics of depression (e.g., symptoms, severity, and treatment response) and patterns of network-based connectivity will facilitate the development of more tailored and effective approaches to the assessment, prevention, and treatment of depression in adolescents. En ligne : http://dx.doi.org/10.1111/jcpp.13250 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1282-1298[article] Research Review: Brain network connectivity and the heterogeneity of depression in adolescence - a precision mental health perspective [Texte imprimé et/ou numérique] / Rajpreet CHAHAL, Auteur ; Ian H. GOTLIB, Auteur ; Amanda E. GUYER, Auteur . - p.1282-1298.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1282-1298
Mots-clés : Depression adolescence brain networks connectivity heterogeneity precision mental health Index. décimale : PER Périodiques Résumé : BACKGROUND: Adolescence is a period of high risk for the onset of depression, characterized by variability in symptoms, severity, and course. During adolescence, the neurocircuitry implicated in depression continues to mature, suggesting that it is an important period for intervention. Reflecting the recent emergence of 'precision mental health' - a person-centered approach to identifying, preventing, and treating psychopathology - researchers have begun to document associations between heterogeneity in features of depression and individual differences in brain circuitry, most frequently in resting-state functional connectivity (RSFC). METHODS: In this review, we present emerging work examining pre- and post-treatment measures of network connectivity in depressed adolescents; these studies reveal potential intervention-specific neural markers of treatment efficacy. We also review findings from studies examining associations between network connectivity and both types of depressive symptoms and response to treatment in adults, and indicate how this work can be extended to depressed adolescents. Finally, we offer recommendations for research that we believe will advance the science of precision mental health of adolescence. RESULTS: Nascent studies suggest that linking RSFC-based pathophysiological variation with effects of different types of treatment and changes in mood following specific interventions will strengthen predictions of prognosis and treatment response. Studies with larger sample sizes and direct comparisons of treatments are required to determine whether RSFC patterns are reliable neuromarkers of treatment response for depressed adolescents. Although we are not yet at the point of using RSFC to guide clinical decision-making, findings from research examining the stability and reliability of RSFC point to a favorable future for network-based clinical phenotyping. CONCLUSIONS: Delineating the correspondence between specific clinical characteristics of depression (e.g., symptoms, severity, and treatment response) and patterns of network-based connectivity will facilitate the development of more tailored and effective approaches to the assessment, prevention, and treatment of depression in adolescents. En ligne : http://dx.doi.org/10.1111/jcpp.13250 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 Structural neural markers of response to cognitive behavioral therapy in pediatric obsessive-compulsive disorder / David PAGLIACCIO in Journal of Child Psychology and Psychiatry, 61-12 (December 2020)
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Titre : Structural neural markers of response to cognitive behavioral therapy in pediatric obsessive-compulsive disorder Type de document : Texte imprimé et/ou numérique Auteurs : David PAGLIACCIO, Auteur ; Jiook CHA, Auteur ; Xiaofu HE, Auteur ; Marilyn CYR, Auteur ; Paula YANES-LUKIN, Auteur ; Pablo GOLDBERG, Auteur ; Martine FONTAINE, Auteur ; Moira A. RYNN, Auteur ; Rachel MARSH, Auteur Article en page(s) : p.1299-1308 Langues : Anglais (eng) Mots-clés : Child development Cognitive therapy Magnetic resonance imaging Obsessive-compulsive disorder Structural MRI (sMRI) Index. décimale : PER Périodiques Résumé : BACKGROUND: Cognitive behavioral therapy (CBT) is an effective, first-line treatment for pediatric obsessive-compulsive disorder (OCD). While neural predictors of treatment outcomes have been identified in adults with OCD, robust predictors are lacking for pediatric patients. Herein, we sought to identify brain structural markers of CBT response in youth with OCD. METHODS: Twenty-eight children/adolescents with OCD and 27 matched healthy participants (7- to 18-year-olds, M = 11.71 years, SD = 3.29) completed high-resolution structural and diffusion MRI (all unmedicated at time of scanning). Patients with OCD then completed 12-16 sessions of CBT. Subcortical volume and cortical thickness were estimated using FreeSurfer. Structural connectivity (streamline counts) was estimated using MRtrix. RESULTS: Thinner cortex in nine frontoparietal regions significantly predicted improvement in Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) scores (all ts > 3.4, FDR-corrected ps < .05). These included middle and superior frontal, angular, lingual, precentral, superior temporal, and supramarginal gyri (SMG). Vertex-wise analyses confirmed a significant left SMG cluster, showing large effect size (Cohen's d = 1.42) with 72.22% specificity and 90.00% sensitivity in predicting CBT response. Ten structural connections between cingulo-opercular regions exhibited fewer streamline counts in OCD (all ts > 3.12, Cohen's ds > 0.92) compared with healthy participants. These connections predicted post-treatment CY-BOCS scores, beyond pretreatment severity and demographics, though not above and beyond cortical thickness. CONCLUSIONS: The current study identified group differences in structural connectivity (reduced among cingulo-opercular regions) and cortical thickness predictors of CBT response (thinner frontoparietal cortices) in unmedicated children/adolescents with OCD. These data suggest, for the first time, that cortical and white matter features of task control circuits may be useful in identifying which pediatric patients respond best to individual CBT. En ligne : http://dx.doi.org/10.1111/jcpp.13191 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1299-1308[article] Structural neural markers of response to cognitive behavioral therapy in pediatric obsessive-compulsive disorder [Texte imprimé et/ou numérique] / David PAGLIACCIO, Auteur ; Jiook CHA, Auteur ; Xiaofu HE, Auteur ; Marilyn CYR, Auteur ; Paula YANES-LUKIN, Auteur ; Pablo GOLDBERG, Auteur ; Martine FONTAINE, Auteur ; Moira A. RYNN, Auteur ; Rachel MARSH, Auteur . - p.1299-1308.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1299-1308
Mots-clés : Child development Cognitive therapy Magnetic resonance imaging Obsessive-compulsive disorder Structural MRI (sMRI) Index. décimale : PER Périodiques Résumé : BACKGROUND: Cognitive behavioral therapy (CBT) is an effective, first-line treatment for pediatric obsessive-compulsive disorder (OCD). While neural predictors of treatment outcomes have been identified in adults with OCD, robust predictors are lacking for pediatric patients. Herein, we sought to identify brain structural markers of CBT response in youth with OCD. METHODS: Twenty-eight children/adolescents with OCD and 27 matched healthy participants (7- to 18-year-olds, M = 11.71 years, SD = 3.29) completed high-resolution structural and diffusion MRI (all unmedicated at time of scanning). Patients with OCD then completed 12-16 sessions of CBT. Subcortical volume and cortical thickness were estimated using FreeSurfer. Structural connectivity (streamline counts) was estimated using MRtrix. RESULTS: Thinner cortex in nine frontoparietal regions significantly predicted improvement in Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) scores (all ts > 3.4, FDR-corrected ps < .05). These included middle and superior frontal, angular, lingual, precentral, superior temporal, and supramarginal gyri (SMG). Vertex-wise analyses confirmed a significant left SMG cluster, showing large effect size (Cohen's d = 1.42) with 72.22% specificity and 90.00% sensitivity in predicting CBT response. Ten structural connections between cingulo-opercular regions exhibited fewer streamline counts in OCD (all ts > 3.12, Cohen's ds > 0.92) compared with healthy participants. These connections predicted post-treatment CY-BOCS scores, beyond pretreatment severity and demographics, though not above and beyond cortical thickness. CONCLUSIONS: The current study identified group differences in structural connectivity (reduced among cingulo-opercular regions) and cortical thickness predictors of CBT response (thinner frontoparietal cortices) in unmedicated children/adolescents with OCD. These data suggest, for the first time, that cortical and white matter features of task control circuits may be useful in identifying which pediatric patients respond best to individual CBT. En ligne : http://dx.doi.org/10.1111/jcpp.13191 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 Volitional eye movement control and ADHD traits: a twin study / Monica SIQUEIROS SANCHEZ in Journal of Child Psychology and Psychiatry, 61-12 (December 2020)
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Titre : Volitional eye movement control and ADHD traits: a twin study Type de document : Texte imprimé et/ou numérique Auteurs : Monica SIQUEIROS SANCHEZ, Auteur ; Terje FALCK-YTTER, Auteur ; Daniel P KENNEDY, Auteur ; Sven BÖLTE, Auteur ; Paul LICHTENSTEIN, Auteur ; Brian M. D'ONOFRIO, Auteur ; Erik PETTERSSON, Auteur Article en page(s) : p.1309-1316 Langues : Anglais (eng) Mots-clés : Attention-deficit/hyperactivity disorder attention behavioral genetics executive function eye movements inhibition oculomotor function Index. décimale : PER Périodiques Résumé : BACKGROUND: Top-down volitional command of eye movements may serve as a candidate endophenotype of ADHD, an important function underlying goal-directed action in everyday life. In this twin study, we examined the relation between performance on a response inhibition eye-tracking paradigm and parent-rated ADHD traits in a population-based twin sample. We hypothesized that altered eye movement control is associated with the severity of ADHD traits and that this association is attributable to genetic factors. METHODS: A total of 640 twins (320 pairs, 50% monozygotic) aged 9-14 years) from the Child and Adolescent Twin Study in Sweden (CATSS) participated. Twins performed the antisaccade task indexing inhibitory alterations as either direction errors (following exogenous cues rather than instructions) or premature anticipatory eye movements (failure to wait for cues). We calculated the associations of eye movement control and ADHD traits using linear regression mixed-effects models and genetic and environmental influences with multivariate twin models. RESULTS: Premature anticipatory eye movements were positively associated with inattentive traits (? = .17; 95% CI: 0.04, 0.31), while controlling for hyperactive behaviors and other covariates. Both premature anticipatory eye movements and inattention were heritable (h(2) = 0.40, 95% CI: 0.22, 0.56; h(2) = 0.55; 95% CI: 0.42, 0.65; respectively), and their genetic correlation was small but statistically significant (r = .19, 95% CI: 0.02, 0.36). However, the genetic correlation did not remain significant after adjusting for covariates (age, sex, hyperactivity traits, IQ). No link was found between direction errors and ADHD traits. CONCLUSIONS: This study indicates that there is a specific, genetically influenced, relation between top-down eye movement control and the inattentive traits typical of ADHD. En ligne : http://dx.doi.org/10.1111/jcpp.13210 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1309-1316[article] Volitional eye movement control and ADHD traits: a twin study [Texte imprimé et/ou numérique] / Monica SIQUEIROS SANCHEZ, Auteur ; Terje FALCK-YTTER, Auteur ; Daniel P KENNEDY, Auteur ; Sven BÖLTE, Auteur ; Paul LICHTENSTEIN, Auteur ; Brian M. D'ONOFRIO, Auteur ; Erik PETTERSSON, Auteur . - p.1309-1316.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1309-1316
Mots-clés : Attention-deficit/hyperactivity disorder attention behavioral genetics executive function eye movements inhibition oculomotor function Index. décimale : PER Périodiques Résumé : BACKGROUND: Top-down volitional command of eye movements may serve as a candidate endophenotype of ADHD, an important function underlying goal-directed action in everyday life. In this twin study, we examined the relation between performance on a response inhibition eye-tracking paradigm and parent-rated ADHD traits in a population-based twin sample. We hypothesized that altered eye movement control is associated with the severity of ADHD traits and that this association is attributable to genetic factors. METHODS: A total of 640 twins (320 pairs, 50% monozygotic) aged 9-14 years) from the Child and Adolescent Twin Study in Sweden (CATSS) participated. Twins performed the antisaccade task indexing inhibitory alterations as either direction errors (following exogenous cues rather than instructions) or premature anticipatory eye movements (failure to wait for cues). We calculated the associations of eye movement control and ADHD traits using linear regression mixed-effects models and genetic and environmental influences with multivariate twin models. RESULTS: Premature anticipatory eye movements were positively associated with inattentive traits (? = .17; 95% CI: 0.04, 0.31), while controlling for hyperactive behaviors and other covariates. Both premature anticipatory eye movements and inattention were heritable (h(2) = 0.40, 95% CI: 0.22, 0.56; h(2) = 0.55; 95% CI: 0.42, 0.65; respectively), and their genetic correlation was small but statistically significant (r = .19, 95% CI: 0.02, 0.36). However, the genetic correlation did not remain significant after adjusting for covariates (age, sex, hyperactivity traits, IQ). No link was found between direction errors and ADHD traits. CONCLUSIONS: This study indicates that there is a specific, genetically influenced, relation between top-down eye movement control and the inattentive traits typical of ADHD. En ligne : http://dx.doi.org/10.1111/jcpp.13210 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 Exploring the cognitive, emotional and sensory correlates of social anxiety in autistic and neurotypical adolescents / Hannah PICKARD in Journal of Child Psychology and Psychiatry, 61-12 (December 2020)
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Titre : Exploring the cognitive, emotional and sensory correlates of social anxiety in autistic and neurotypical adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Hannah PICKARD, Auteur ; Colette HIRSCH, Auteur ; Emily SIMONOFF, Auteur ; Francesca HAPPE, Auteur Article en page(s) : p.1317-1327 Langues : Anglais (eng) Mots-clés : Autism adolescence cognition emotion social anxiety Index. décimale : PER Périodiques Résumé : BACKGROUND: Social anxiety is common in autistic adolescents. While emerging evidence indicates the importance of several mechanisms (including intolerance of uncertainty (IU), alexithymia and sensory processing) for maintaining anxiety, limited research has explored how these factors are associated with social anxiety in autistic adolescents. METHODS: We investigated whether IU, emotional and sensory processing are related to social anxiety in autistic and neurotypical adolescents, gathering experimental and questionnaire data from 61 autistic and 62 neurotypical 11- to 17-year-olds recruited to have similarly high levels of anxiety. RESULTS: In autistic and neurotypical adolescents matched for social anxiety, similar significant associations were observed between social anxiety and IU, alexithymia, maladaptive emotion regulation, sensory hypersensitivity and interoceptive sensibility. Taking a dimensional approach, we found that child- and parent-reported IU, alexithymia and sensory hypersensitivity mediated the relationship between autistic traits and social anxiety symptoms in the combined group of adolescents. CONCLUSIONS: Our findings indicate that similar correlates of social anxiety are evident in autistic and neurotypical youths experiencing social anxiety and further our understanding of mechanisms that may contribute towards social anxiety in both groups. En ligne : http://dx.doi.org/10.1111/jcpp.13214 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1317-1327[article] Exploring the cognitive, emotional and sensory correlates of social anxiety in autistic and neurotypical adolescents [Texte imprimé et/ou numérique] / Hannah PICKARD, Auteur ; Colette HIRSCH, Auteur ; Emily SIMONOFF, Auteur ; Francesca HAPPE, Auteur . - p.1317-1327.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1317-1327
Mots-clés : Autism adolescence cognition emotion social anxiety Index. décimale : PER Périodiques Résumé : BACKGROUND: Social anxiety is common in autistic adolescents. While emerging evidence indicates the importance of several mechanisms (including intolerance of uncertainty (IU), alexithymia and sensory processing) for maintaining anxiety, limited research has explored how these factors are associated with social anxiety in autistic adolescents. METHODS: We investigated whether IU, emotional and sensory processing are related to social anxiety in autistic and neurotypical adolescents, gathering experimental and questionnaire data from 61 autistic and 62 neurotypical 11- to 17-year-olds recruited to have similarly high levels of anxiety. RESULTS: In autistic and neurotypical adolescents matched for social anxiety, similar significant associations were observed between social anxiety and IU, alexithymia, maladaptive emotion regulation, sensory hypersensitivity and interoceptive sensibility. Taking a dimensional approach, we found that child- and parent-reported IU, alexithymia and sensory hypersensitivity mediated the relationship between autistic traits and social anxiety symptoms in the combined group of adolescents. CONCLUSIONS: Our findings indicate that similar correlates of social anxiety are evident in autistic and neurotypical youths experiencing social anxiety and further our understanding of mechanisms that may contribute towards social anxiety in both groups. En ligne : http://dx.doi.org/10.1111/jcpp.13214 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 Content, diagnostic, correlational, and genetic similarities between common measures of childhood aggressive behaviors and related psychiatric traits / Anne M. HENDRIKS in Journal of Child Psychology and Psychiatry, 61-12 (December 2020)
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Titre : Content, diagnostic, correlational, and genetic similarities between common measures of childhood aggressive behaviors and related psychiatric traits Type de document : Texte imprimé et/ou numérique Auteurs : Anne M. HENDRIKS, Auteur ; Hill F IP, Auteur ; Michel G. NIVARD, Auteur ; Catrin FINKENAUER, Auteur ; Catharina E. M. VAN BEIJSTERVELDT, Auteur ; Meike BARTELS, Auteur ; Dorret I. BOOMSMA, Auteur Article en page(s) : p.1328-1338 Langues : Anglais (eng) Mots-clés : Childhood aggressive behavior clinical concordance genetic correlation item overlap Index. décimale : PER Périodiques Résumé : BACKGROUND: Given the role of childhood aggressive behavior (AGG) in everyday child development, precise and accurate measurement is critical in clinical practice and research. This study aims to quantify agreement among widely used measures of childhood AGG regarding item content, clinical concordance, correlation, and underlying genetic construct. METHODS: We analyzed data from 1254 Dutch twin pairs (age 8-10 years, 51.1% boys) from a general population sample for whom both parents completed the A-TAC, CBCL, and SDQ at the same occasion. RESULTS: There was substantial variation in item content among AGG measures, ranging from .00 (i.e., mutually exclusive) to .50 (moderate agreement). Clinical concordance (i.e., do the same children score above a clinical threshold among AGG measures) was very weak to moderate with estimates ranging between .01 and .43 for mother-reports and between .12 and .42 for father-reports. Correlations among scales were weak to strong, ranging from .32 to .70 for mother-reports and from .32 to .64 for father-reports. We found weak to very strong genetic correlations among the measures, with estimates between .65 and .84 for mother-reports and between .30 and .87 for father-reports. CONCLUSIONS: Our results demonstrated that degree of agreement between measures of AGG depends on the type (i.e., item content, clinical concordance, correlation, genetic correlation) of agreement considered. Because agreement was higher for correlations compared to clinical concordance (i.e., above or below a clinical cutoff), we propose the use of continuous scores to assess AGG, especially for combining data with different measures. Although item content can be different and agreement among observed measures may not be high, the genetic correlations indicate that the underlying genetic liability for childhood AGG is consistent across measures. En ligne : http://dx.doi.org/10.1111/jcpp.13218 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1328-1338[article] Content, diagnostic, correlational, and genetic similarities between common measures of childhood aggressive behaviors and related psychiatric traits [Texte imprimé et/ou numérique] / Anne M. HENDRIKS, Auteur ; Hill F IP, Auteur ; Michel G. NIVARD, Auteur ; Catrin FINKENAUER, Auteur ; Catharina E. M. VAN BEIJSTERVELDT, Auteur ; Meike BARTELS, Auteur ; Dorret I. BOOMSMA, Auteur . - p.1328-1338.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1328-1338
Mots-clés : Childhood aggressive behavior clinical concordance genetic correlation item overlap Index. décimale : PER Périodiques Résumé : BACKGROUND: Given the role of childhood aggressive behavior (AGG) in everyday child development, precise and accurate measurement is critical in clinical practice and research. This study aims to quantify agreement among widely used measures of childhood AGG regarding item content, clinical concordance, correlation, and underlying genetic construct. METHODS: We analyzed data from 1254 Dutch twin pairs (age 8-10 years, 51.1% boys) from a general population sample for whom both parents completed the A-TAC, CBCL, and SDQ at the same occasion. RESULTS: There was substantial variation in item content among AGG measures, ranging from .00 (i.e., mutually exclusive) to .50 (moderate agreement). Clinical concordance (i.e., do the same children score above a clinical threshold among AGG measures) was very weak to moderate with estimates ranging between .01 and .43 for mother-reports and between .12 and .42 for father-reports. Correlations among scales were weak to strong, ranging from .32 to .70 for mother-reports and from .32 to .64 for father-reports. We found weak to very strong genetic correlations among the measures, with estimates between .65 and .84 for mother-reports and between .30 and .87 for father-reports. CONCLUSIONS: Our results demonstrated that degree of agreement between measures of AGG depends on the type (i.e., item content, clinical concordance, correlation, genetic correlation) of agreement considered. Because agreement was higher for correlations compared to clinical concordance (i.e., above or below a clinical cutoff), we propose the use of continuous scores to assess AGG, especially for combining data with different measures. Although item content can be different and agreement among observed measures may not be high, the genetic correlations indicate that the underlying genetic liability for childhood AGG is consistent across measures. En ligne : http://dx.doi.org/10.1111/jcpp.13218 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 The unique contribution of blushing to the development of social anxiety disorder symptoms: results from a longitudinal study / Milica NIKOLIC in Journal of Child Psychology and Psychiatry, 61-12 (December 2020)
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[article]
Titre : The unique contribution of blushing to the development of social anxiety disorder symptoms: results from a longitudinal study Type de document : Texte imprimé et/ou numérique Auteurs : Milica NIKOLIC, Auteur ; Mirjana MAJDANDŽI?, Auteur ; Cristina COLONNESI, Auteur ; Wieke DE VENTE, Auteur ; Eline MÖLLER, Auteur ; Susan M. BOGELS, Auteur Article en page(s) : p.1339-1348 Langues : Anglais (eng) Mots-clés : Social anxiety disorder behavioral inhibition blushing self-consciousness Index. décimale : PER Périodiques Résumé : BACKGROUND: Self-conscious emotional reactivity and its physiological marker - blushing has been proposed to be an etiological mechanism of social anxiety disorder (SAD), but so far, untested in longitudinal designs. This study tested, for the first time, whether self-conscious emotional reactivity (indexed as physiological blushing) contributes to the development of SAD symptoms over and above social behavioral inhibition (BI), which has been identified as the strongest predictor of SAD development in early childhood. METHODS: One hundred fifteen children (45% boys) and their mothers and fathers participated at ages 2.5, 4.5, and 7.5 years. Social BI was observed at all time points in a stranger approach task, and physiological blushing (blood volume, blood pulse amplitude, and temperature increases) was measured during a public performance (singing) and watching back the performance at ages 4.5 and 7.5. Child early social anxiety was reported by both parents at 4.5 years, and SAD symptoms were diagnosed by clinicians and reported by both parents at 7.5 years. RESULTS: Higher social BI at 2.5 and 4.5 years predicted greater social anxiety at 4.5 years, which, in turn, predicted SAD symptoms at 7.5 years. Blushing (temperature increase) at 4.5 years predicted SAD symptoms at 7.5 years over and above the influence of social BI and early social anxiety. CONCLUSIONS: That blushing uniquely contributes to the development of SAD symptoms over and above social BI suggests two pathways to childhood SAD: one that entails early high social BI and an early onset of social anxiety symptoms, and the other that consists of heightened self-conscious emotional reactivity (i.e. blushing) in early childhood. En ligne : http://dx.doi.org/10.1111/jcpp.13221 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1339-1348[article] The unique contribution of blushing to the development of social anxiety disorder symptoms: results from a longitudinal study [Texte imprimé et/ou numérique] / Milica NIKOLIC, Auteur ; Mirjana MAJDANDŽI?, Auteur ; Cristina COLONNESI, Auteur ; Wieke DE VENTE, Auteur ; Eline MÖLLER, Auteur ; Susan M. BOGELS, Auteur . - p.1339-1348.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1339-1348
Mots-clés : Social anxiety disorder behavioral inhibition blushing self-consciousness Index. décimale : PER Périodiques Résumé : BACKGROUND: Self-conscious emotional reactivity and its physiological marker - blushing has been proposed to be an etiological mechanism of social anxiety disorder (SAD), but so far, untested in longitudinal designs. This study tested, for the first time, whether self-conscious emotional reactivity (indexed as physiological blushing) contributes to the development of SAD symptoms over and above social behavioral inhibition (BI), which has been identified as the strongest predictor of SAD development in early childhood. METHODS: One hundred fifteen children (45% boys) and their mothers and fathers participated at ages 2.5, 4.5, and 7.5 years. Social BI was observed at all time points in a stranger approach task, and physiological blushing (blood volume, blood pulse amplitude, and temperature increases) was measured during a public performance (singing) and watching back the performance at ages 4.5 and 7.5. Child early social anxiety was reported by both parents at 4.5 years, and SAD symptoms were diagnosed by clinicians and reported by both parents at 7.5 years. RESULTS: Higher social BI at 2.5 and 4.5 years predicted greater social anxiety at 4.5 years, which, in turn, predicted SAD symptoms at 7.5 years. Blushing (temperature increase) at 4.5 years predicted SAD symptoms at 7.5 years over and above the influence of social BI and early social anxiety. CONCLUSIONS: That blushing uniquely contributes to the development of SAD symptoms over and above social BI suggests two pathways to childhood SAD: one that entails early high social BI and an early onset of social anxiety symptoms, and the other that consists of heightened self-conscious emotional reactivity (i.e. blushing) in early childhood. En ligne : http://dx.doi.org/10.1111/jcpp.13221 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 A polygenic score for age-at-first-birth predicts disinhibition / Leah S. RICHMOND-RAKERD in Journal of Child Psychology and Psychiatry, 61-12 (December 2020)
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[article]
Titre : A polygenic score for age-at-first-birth predicts disinhibition Type de document : Texte imprimé et/ou numérique Auteurs : Leah S. RICHMOND-RAKERD, Auteur ; Terrie E. MOFFITT, Auteur ; Louise ARSENEAULT, Auteur ; Daniel W. BELSKY, Auteur ; Jennie CONNOR, Auteur ; David L. CORCORAN, Auteur ; Honalee HARRINGTON, Auteur ; Renate M. HOUTS, Auteur ; Richie POULTON, Auteur ; Joey A. PRINZ, Auteur ; Sandhya RAMRAKHA, Auteur ; Karen SUGDEN, Auteur ; Jasmin WERTZ, Auteur ; Benjamin S. WILLIAMS, Auteur ; Avshalom CASPI, Auteur Article en page(s) : p.1349-1359 Langues : Anglais (eng) Mots-clés : Reproductive behavior genetics longitudinal risk-taking self-control Index. décimale : PER Périodiques Résumé : BACKGROUND: A recent genome-wide association study identified molecular-genetic associations with age-at-first-birth. However, the meaning of these genetic discoveries is unclear. Drawing on evidence linking early pregnancy with disinhibitory behavior, we tested the hypothesis that genetic discoveries for age-at-first-birth predict disinhibition. METHODS: We included participants with genotype data from the two-decade-long Environmental Risk (E-Risk) Study (N = 1,999) and the four-decade-long Dunedin Study (N = 918). We calculated a genome-wide polygenic score for age-at-first-birth and tested whether it was associated with a range of disinhibitory outcomes across the life course, including low childhood self-control; risk for externalizing psychopathology; officially recorded criminal offending; substance dependence; informant reports of disinhibitory problems; and number of lifetime sexual partners. We further tested whether associations were attributable to accelerated pubertal maturation. RESULTS: In both cohorts, the age-at-first-birth polygenic score predicted low childhood self-control, externalizing psychopathology, officially recorded criminal offending, substance dependence, and number of sexual partners. Associations were modest, but robust across replication. Childhood disinhibition partly mediated associations between the polygenic score and reproductive behaviors. In contrast, associations were not attributable to accelerated pubertal timing. CONCLUSIONS: Genomic discoveries for age-at-first-birth are about more than reproductive biology: They provide insight into the disinhibitory traits and behaviors that accompany early parenthood. Age-at-first-birth is a useful proxy phenotype for researchers interested in disinhibition. Further, interventions that improve self-regulation abilities may benefit young parents and their children. En ligne : http://dx.doi.org/10.1111/jcpp.13224 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1349-1359[article] A polygenic score for age-at-first-birth predicts disinhibition [Texte imprimé et/ou numérique] / Leah S. RICHMOND-RAKERD, Auteur ; Terrie E. MOFFITT, Auteur ; Louise ARSENEAULT, Auteur ; Daniel W. BELSKY, Auteur ; Jennie CONNOR, Auteur ; David L. CORCORAN, Auteur ; Honalee HARRINGTON, Auteur ; Renate M. HOUTS, Auteur ; Richie POULTON, Auteur ; Joey A. PRINZ, Auteur ; Sandhya RAMRAKHA, Auteur ; Karen SUGDEN, Auteur ; Jasmin WERTZ, Auteur ; Benjamin S. WILLIAMS, Auteur ; Avshalom CASPI, Auteur . - p.1349-1359.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1349-1359
Mots-clés : Reproductive behavior genetics longitudinal risk-taking self-control Index. décimale : PER Périodiques Résumé : BACKGROUND: A recent genome-wide association study identified molecular-genetic associations with age-at-first-birth. However, the meaning of these genetic discoveries is unclear. Drawing on evidence linking early pregnancy with disinhibitory behavior, we tested the hypothesis that genetic discoveries for age-at-first-birth predict disinhibition. METHODS: We included participants with genotype data from the two-decade-long Environmental Risk (E-Risk) Study (N = 1,999) and the four-decade-long Dunedin Study (N = 918). We calculated a genome-wide polygenic score for age-at-first-birth and tested whether it was associated with a range of disinhibitory outcomes across the life course, including low childhood self-control; risk for externalizing psychopathology; officially recorded criminal offending; substance dependence; informant reports of disinhibitory problems; and number of lifetime sexual partners. We further tested whether associations were attributable to accelerated pubertal maturation. RESULTS: In both cohorts, the age-at-first-birth polygenic score predicted low childhood self-control, externalizing psychopathology, officially recorded criminal offending, substance dependence, and number of sexual partners. Associations were modest, but robust across replication. Childhood disinhibition partly mediated associations between the polygenic score and reproductive behaviors. In contrast, associations were not attributable to accelerated pubertal timing. CONCLUSIONS: Genomic discoveries for age-at-first-birth are about more than reproductive biology: They provide insight into the disinhibitory traits and behaviors that accompany early parenthood. Age-at-first-birth is a useful proxy phenotype for researchers interested in disinhibition. Further, interventions that improve self-regulation abilities may benefit young parents and their children. En ligne : http://dx.doi.org/10.1111/jcpp.13224 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 Social communication deficits following early-life deprivation and relation to psychopathology: a randomized clinical trial of foster care / Mark WADE in Journal of Child Psychology and Psychiatry, 61-12 (December 2020)
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[article]
Titre : Social communication deficits following early-life deprivation and relation to psychopathology: a randomized clinical trial of foster care Type de document : Texte imprimé et/ou numérique Auteurs : Mark WADE, Auteur ; Charles H. ZEANAH, Auteur ; Nathan A. FOX, Auteur ; Charles A. NELSON, Auteur Article en page(s) : p.1360-1369 Langues : Anglais (eng) Mots-clés : Institutional rearing foster care intervention maltreatment psychopathology severe early neglect social communication Index. décimale : PER Périodiques Résumé : BACKGROUND: Children reared in institutions experience profound deprivation that is linked to impairments in social communication (SC). However, little is known about the long-term consequences of institutional rearing on SC through adolescence, and how SC deficits relate to broad-spectrum psychopathology. It is also unclear whether early removal from deprivation and placement into socially enriched environments remediates these difficulties. METHODS: Children reared in Romanian institutions from the Bucharest Early Intervention Project were randomly assigned to care as usual or foster care intervention in early childhood. An age- and sex-matched group of never-institutionalized children was also recruited. SC data from 208 children at age 8 and 129 children at 16 were collected using the Social Communication Questionnaire. Psychopathology was assessed as saved factor scores for general (P) and specific internalizing (INT) and externalizing (EXT) problems. We examined (a) whether institutional rearing is associated with continued SC deficits into adolescence; (b) whether early placement into foster care mitigates risk for SC problems; and (c) associations between SC and psychopathology from middle childhood (age 8) to adolescence (age 16). RESULTS: Findings suggest that: (a) institutionally-reared children have significantly more SC problems than never-institutionalized children at age 16; (b) children placed into foster care early in life have fewer problems with reciprocal social interaction compared to those with prolonged institutional rearing; and (c) deficits in SC at age 8 partially account for the link between institutional rearing and general psychopathology at age 16. CONCLUSIONS: Early deprivation is associated with impairments in SC that persist into adolescence, with evidence for the remedial benefit of family-based care in the domain of reciprocal social interaction. Moreover, deficits in SC among ever-institutionalized children in middle childhood may increase the risk of broad-spectrum psychopathology in adolescence, thus providing one putative target for early intervention to safeguard against later psychiatric problems. En ligne : http://dx.doi.org/10.1111/jcpp.13222 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1360-1369[article] Social communication deficits following early-life deprivation and relation to psychopathology: a randomized clinical trial of foster care [Texte imprimé et/ou numérique] / Mark WADE, Auteur ; Charles H. ZEANAH, Auteur ; Nathan A. FOX, Auteur ; Charles A. NELSON, Auteur . - p.1360-1369.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1360-1369
Mots-clés : Institutional rearing foster care intervention maltreatment psychopathology severe early neglect social communication Index. décimale : PER Périodiques Résumé : BACKGROUND: Children reared in institutions experience profound deprivation that is linked to impairments in social communication (SC). However, little is known about the long-term consequences of institutional rearing on SC through adolescence, and how SC deficits relate to broad-spectrum psychopathology. It is also unclear whether early removal from deprivation and placement into socially enriched environments remediates these difficulties. METHODS: Children reared in Romanian institutions from the Bucharest Early Intervention Project were randomly assigned to care as usual or foster care intervention in early childhood. An age- and sex-matched group of never-institutionalized children was also recruited. SC data from 208 children at age 8 and 129 children at 16 were collected using the Social Communication Questionnaire. Psychopathology was assessed as saved factor scores for general (P) and specific internalizing (INT) and externalizing (EXT) problems. We examined (a) whether institutional rearing is associated with continued SC deficits into adolescence; (b) whether early placement into foster care mitigates risk for SC problems; and (c) associations between SC and psychopathology from middle childhood (age 8) to adolescence (age 16). RESULTS: Findings suggest that: (a) institutionally-reared children have significantly more SC problems than never-institutionalized children at age 16; (b) children placed into foster care early in life have fewer problems with reciprocal social interaction compared to those with prolonged institutional rearing; and (c) deficits in SC at age 8 partially account for the link between institutional rearing and general psychopathology at age 16. CONCLUSIONS: Early deprivation is associated with impairments in SC that persist into adolescence, with evidence for the remedial benefit of family-based care in the domain of reciprocal social interaction. Moreover, deficits in SC among ever-institutionalized children in middle childhood may increase the risk of broad-spectrum psychopathology in adolescence, thus providing one putative target for early intervention to safeguard against later psychiatric problems. En ligne : http://dx.doi.org/10.1111/jcpp.13222 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 Machine-Learning prediction of comorbid substance use disorders in ADHD youth using Swedish registry data / Yanli ZHANG-JAMES in Journal of Child Psychology and Psychiatry, 61-12 (December 2020)
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[article]
Titre : Machine-Learning prediction of comorbid substance use disorders in ADHD youth using Swedish registry data Type de document : Texte imprimé et/ou numérique Auteurs : Yanli ZHANG-JAMES, Auteur ; Qi CHEN, Auteur ; Ralf KUJA-HALKOLA, Auteur ; Paul LICHTENSTEIN, Auteur ; Henrik LARSSON, Auteur ; Stephen V. FARAONE, Auteur Article en page(s) : p.1370-1379 Langues : Anglais (eng) Mots-clés : Machine learning attention-deficit hyperactive disorder comorbidity risk factor substance use disorder Index. décimale : PER Périodiques Résumé : BACKGROUND: Children with attention-deficit/hyperactivity disorder (ADHD) have a high risk for substance use disorders (SUDs). Early identification of at-risk youth would help allocate scarce resources for prevention programs. METHODS: Psychiatric and somatic diagnoses, family history of these disorders, measures of socioeconomic distress, and information about birth complications were obtained from the national registers in Sweden for 19,787 children with ADHD born between 1989 and 1993. We trained (a) a cross-sectional random forest (RF) model using data available by age 17 to predict SUD diagnosis between ages 18 and 19; and (b) a longitudinal recurrent neural network (RNN) model with the Long Short-Term Memory (LSTM) architecture to predict new diagnoses at each age. RESULTS: The area under the receiver operating characteristic curve (AUC) was 0.73(95%CI 0.70-0.76) for the random forest model (RF). Removing prior diagnosis from the predictors, the RF model was still able to achieve significant AUCs when predicting all SUD diagnoses (0.69, 95%CI 0.66-0.72) or new diagnoses (0.67, 95%CI: 0.64, 0.71) during age 18-19. For the model predicting new diagnoses, model calibration was good with a low Brier score of 0.086. Longitudinal LSTM model was able to predict later SUD risks at as early as 2 years age, 10 years before the earliest diagnosis. The average AUC from longitudinal models predicting new diagnoses 1, 2, 5 and 10 years in the future was 0.63. CONCLUSIONS: Population registry data can be used to predict at-risk comorbid SUDs in individuals with ADHD. Such predictions can be made many years prior to age of the onset, and their SUD risks can be monitored using longitudinal models over years during child development. Nevertheless, more work is needed to create prediction models based on electronic health records or linked population registers that are sufficiently accurate for use in the clinic. En ligne : http://dx.doi.org/10.1111/jcpp.13226 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1370-1379[article] Machine-Learning prediction of comorbid substance use disorders in ADHD youth using Swedish registry data [Texte imprimé et/ou numérique] / Yanli ZHANG-JAMES, Auteur ; Qi CHEN, Auteur ; Ralf KUJA-HALKOLA, Auteur ; Paul LICHTENSTEIN, Auteur ; Henrik LARSSON, Auteur ; Stephen V. FARAONE, Auteur . - p.1370-1379.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1370-1379
Mots-clés : Machine learning attention-deficit hyperactive disorder comorbidity risk factor substance use disorder Index. décimale : PER Périodiques Résumé : BACKGROUND: Children with attention-deficit/hyperactivity disorder (ADHD) have a high risk for substance use disorders (SUDs). Early identification of at-risk youth would help allocate scarce resources for prevention programs. METHODS: Psychiatric and somatic diagnoses, family history of these disorders, measures of socioeconomic distress, and information about birth complications were obtained from the national registers in Sweden for 19,787 children with ADHD born between 1989 and 1993. We trained (a) a cross-sectional random forest (RF) model using data available by age 17 to predict SUD diagnosis between ages 18 and 19; and (b) a longitudinal recurrent neural network (RNN) model with the Long Short-Term Memory (LSTM) architecture to predict new diagnoses at each age. RESULTS: The area under the receiver operating characteristic curve (AUC) was 0.73(95%CI 0.70-0.76) for the random forest model (RF). Removing prior diagnosis from the predictors, the RF model was still able to achieve significant AUCs when predicting all SUD diagnoses (0.69, 95%CI 0.66-0.72) or new diagnoses (0.67, 95%CI: 0.64, 0.71) during age 18-19. For the model predicting new diagnoses, model calibration was good with a low Brier score of 0.086. Longitudinal LSTM model was able to predict later SUD risks at as early as 2 years age, 10 years before the earliest diagnosis. The average AUC from longitudinal models predicting new diagnoses 1, 2, 5 and 10 years in the future was 0.63. CONCLUSIONS: Population registry data can be used to predict at-risk comorbid SUDs in individuals with ADHD. Such predictions can be made many years prior to age of the onset, and their SUD risks can be monitored using longitudinal models over years during child development. Nevertheless, more work is needed to create prediction models based on electronic health records or linked population registers that are sufficiently accurate for use in the clinic. En ligne : http://dx.doi.org/10.1111/jcpp.13226 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 Moderate-to-vigorous physical activity and processing speed: predicting adaptive change in ADHD levels and related impairments in preschoolers / Betsy HOZA in Journal of Child Psychology and Psychiatry, 61-12 (December 2020)
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[article]
Titre : Moderate-to-vigorous physical activity and processing speed: predicting adaptive change in ADHD levels and related impairments in preschoolers Type de document : Texte imprimé et/ou numérique Auteurs : Betsy HOZA, Auteur ; Erin K. SHOULBERG, Auteur ; Connie L. TOMPKINS, Auteur ; Caroline P. MARTIN, Auteur ; Allison KRASNER, Auteur ; Marissa DENNIS, Auteur ; Lori E. MEYER, Auteur ; Hannah COOK, Auteur Article en page(s) : p.1380-1387 Langues : Anglais (eng) Mots-clés : Attention-deficit/hyperactivity disorder (ADHD) early intervention moderate-to-vigorous physical activity (MVPA) physical activity (PA) preschool prevention processing speed (PS) Index. décimale : PER Périodiques Résumé : BACKGROUND: Preschool ADHD symptoms have predictive utility for later presence of ADHD diagnoses (Harvey, Youngwirth, Thakar, & Errazuriz, 2009, Journal of Consulting and Clinical Psychology, 77, 349; Lahey et al., 2004, American Journal of Psychiatry, 161(11), 2014), yet some level of inattention, hyperactivity, and impulsivity are present even in typically developing preschoolers. Physical activity (PA) is known to have a broad spectrum of positive effects on the brain in school-age typically developing children (Centers for Disease Control and Prevention, 2010, The association between school based physical activity, including physical education, and academic performance. Atlanta, GA: U.S. Department of Health and Human Services), including functions impaired by ADHD (Halperin, Berwid, & O'Neill, 2014, Child and Adolescent Psychiatric Clinics of North America, 23, 899), yet links between PA and ADHD levels and impairments have rarely been studied in either typically developing or at-risk preschool children. Importantly, impaired processing speed (PS), though not a symptom of ADHD, is a robust neuropsychological correlate (Willcutt & Bidwell, 2011, Treating attention deficit hyperactivity disorder: Assessment and intervention in developmental context. Kingston, NJ: Civic Research Institute) that may indicate additional risk for ADHD. Hence, we examined whether baseline PS moderates the association between preschoolers' PA, specifically moderate-to-vigorous PA (MVPA), and changes in ADHD levels and related behaviors. METHOD: Eighty-five preschoolers (49.4% female; M(age) = 4.14, SD(age) = .64) were drawn from a larger study of the effects of the Kiddie Children and Teachers (CATs) on the Move PA program on school readiness. The sample was largely Head Start eligible (68.2%) and ethnically diverse. Hierarchical regressions were utilized to examine links between MVPA, averaged over a school year, and changes in inattention (IA), hyperactivity/impulsivity (HI), oppositional behaviors, moodiness, and peer functioning, and whether these associations varied based on baseline PS. RESULTS: Results indicated that for IA, HI, and peer functioning, higher amounts of MVPA were associated with greater adaptive change for those with lower (but not higher) levels of PS. CONCLUSIONS: Preschool MVPA may be a viable method of reducing ADHD levels and impairments for those with lower PS. En ligne : http://dx.doi.org/10.1111/jcpp.13227 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1380-1387[article] Moderate-to-vigorous physical activity and processing speed: predicting adaptive change in ADHD levels and related impairments in preschoolers [Texte imprimé et/ou numérique] / Betsy HOZA, Auteur ; Erin K. SHOULBERG, Auteur ; Connie L. TOMPKINS, Auteur ; Caroline P. MARTIN, Auteur ; Allison KRASNER, Auteur ; Marissa DENNIS, Auteur ; Lori E. MEYER, Auteur ; Hannah COOK, Auteur . - p.1380-1387.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1380-1387
Mots-clés : Attention-deficit/hyperactivity disorder (ADHD) early intervention moderate-to-vigorous physical activity (MVPA) physical activity (PA) preschool prevention processing speed (PS) Index. décimale : PER Périodiques Résumé : BACKGROUND: Preschool ADHD symptoms have predictive utility for later presence of ADHD diagnoses (Harvey, Youngwirth, Thakar, & Errazuriz, 2009, Journal of Consulting and Clinical Psychology, 77, 349; Lahey et al., 2004, American Journal of Psychiatry, 161(11), 2014), yet some level of inattention, hyperactivity, and impulsivity are present even in typically developing preschoolers. Physical activity (PA) is known to have a broad spectrum of positive effects on the brain in school-age typically developing children (Centers for Disease Control and Prevention, 2010, The association between school based physical activity, including physical education, and academic performance. Atlanta, GA: U.S. Department of Health and Human Services), including functions impaired by ADHD (Halperin, Berwid, & O'Neill, 2014, Child and Adolescent Psychiatric Clinics of North America, 23, 899), yet links between PA and ADHD levels and impairments have rarely been studied in either typically developing or at-risk preschool children. Importantly, impaired processing speed (PS), though not a symptom of ADHD, is a robust neuropsychological correlate (Willcutt & Bidwell, 2011, Treating attention deficit hyperactivity disorder: Assessment and intervention in developmental context. Kingston, NJ: Civic Research Institute) that may indicate additional risk for ADHD. Hence, we examined whether baseline PS moderates the association between preschoolers' PA, specifically moderate-to-vigorous PA (MVPA), and changes in ADHD levels and related behaviors. METHOD: Eighty-five preschoolers (49.4% female; M(age) = 4.14, SD(age) = .64) were drawn from a larger study of the effects of the Kiddie Children and Teachers (CATs) on the Move PA program on school readiness. The sample was largely Head Start eligible (68.2%) and ethnically diverse. Hierarchical regressions were utilized to examine links between MVPA, averaged over a school year, and changes in inattention (IA), hyperactivity/impulsivity (HI), oppositional behaviors, moodiness, and peer functioning, and whether these associations varied based on baseline PS. RESULTS: Results indicated that for IA, HI, and peer functioning, higher amounts of MVPA were associated with greater adaptive change for those with lower (but not higher) levels of PS. CONCLUSIONS: Preschool MVPA may be a viable method of reducing ADHD levels and impairments for those with lower PS. En ligne : http://dx.doi.org/10.1111/jcpp.13227 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 Editorial Perspective: Stop describing and start fixing - the promise of longitudinal intervention cohorts / Mark TOMLINSON in Journal of Child Psychology and Psychiatry, 61-12 (December 2020)
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[article]
Titre : Editorial Perspective: Stop describing and start fixing - the promise of longitudinal intervention cohorts Type de document : Texte imprimé et/ou numérique Auteurs : Mark TOMLINSON, Auteur ; Richard M. PASCO FEARON, Auteur ; Joan CHRISTODOULOU, Auteur ; Mary Jane ROTHERAM-BORUS, Auteur Article en page(s) : p.1388-1390 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1111/jcpp.13213 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1388-1390[article] Editorial Perspective: Stop describing and start fixing - the promise of longitudinal intervention cohorts [Texte imprimé et/ou numérique] / Mark TOMLINSON, Auteur ; Richard M. PASCO FEARON, Auteur ; Joan CHRISTODOULOU, Auteur ; Mary Jane ROTHERAM-BORUS, Auteur . - p.1388-1390.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-12 (December 2020) . - p.1388-1390
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1111/jcpp.13213 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434