49 recherche sur le mot-clé 'Cohort studies'

Association of maternal autoimmune disease and early childhood infections with offspring autism spectrum disorder: A population-based cohort study / Timothy C. NIELSEN in Autism Research, 15-12 (December 2022)  

Public ISBD [article]  inAutism Research > 15-12 (December 2022) . - p.2371-2380 Titre : Association of maternal autoimmune disease and early childhood infections with offspring autism spectrum disorder: A population-based cohort study Type de document : Texte imprimé et/ou numérique Auteurs : Timothy C. NIELSEN, Auteur ; Natasha NASSAR, Auteur ; Antonia W. SHAND, Auteur ; Hannah F. JONES, Auteur ; Velda X. HAN, Auteur ; Shrujna PATEL, Auteur ; Adam J. GUASTELLA, Auteur ; Russell C DALE, Auteur ; Samantha J. LAIN, Auteur Article en page(s) : p.2371-2380 Langues : Anglais (eng) Mots-clés : Child  Child, Preschool  Humans  Autism Spectrum Disorder/epidemiology/etiology  Cohort Studies  Odds Ratio  Logistic Models  Autoimmune Diseases/epidemiology/complications  Australia  autism Spectrum disorder  autoimmune diseases  infections  pregnancy Index. décimale : PER Périodiques Résumé : The aim of this study was to examine potential synergistic effects between maternal autoimmune disease and early childhood infections and their association with autism spectrum disorder (ASD) in offspring. Both exposures have been associated with increased risk of ASD in previous studies, but potential synergistic effects remain underexplored. We conducted a population-based cohort study of singleton children born at term gestation (37-41 weeks) in New South Wales, Australia from January 2002 to December 2008. Maternal autoimmune diagnoses and childhood infections before age 2 years were identified from linked maternal and child hospital admissions, and ASD diagnoses by age 9 years were identified from linked disability services data. Multivariable logistic regression assessed the association between each exposure and ASD and additive interaction between exposures, controlling for potential confounders. A total of 18,451 children exposed to maternal autoimmune disease were propensity score matched (1:2) to 36,902 unexposed children. Any maternal autoimmune disease (adjusted odds ratio (aOR) 1.25, 95% confidence interval (CI) 1.07-1.47) and any childhood infection before age 2 years (aOR 1.38, 95% CI 1.15-1.67) were each associated with ASD. However, there was no evidence of additive interaction between the two exposures (relative excess risk due to interaction [RERI] 0.128, 95% CI -0.418-0.675) resulting in increased odds of ASD in offspring. Future studies could examine potential interactions between other sources of maternal immune activation and childhood infection and impact on ASD and other neurodevelopmental disorders. En ligne : http://dx.doi.org/10.1002/aur.2824 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 [article] Association of maternal autoimmune disease and early childhood infections with offspring autism spectrum disorder: A population-based cohort study [Texte imprimé et/ou numérique] / Timothy C. NIELSEN, Auteur ; Natasha NASSAR, Auteur ; Antonia W. SHAND, Auteur ; Hannah F. JONES, Auteur ; Velda X. HAN, Auteur ; Shrujna PATEL, Auteur ; Adam J. GUASTELLA, Auteur ; Russell C DALE, Auteur ; Samantha J. LAIN, Auteur . - p.2371-2380. Langues : Anglais (eng) in Autism Research > 15-12 (December 2022) . - p.2371-2380 Mots-clés : Child  Child, Preschool  Humans  Autism Spectrum Disorder/epidemiology/etiology  Cohort Studies  Odds Ratio  Logistic Models  Autoimmune Diseases/epidemiology/complications  Australia  autism Spectrum disorder  autoimmune diseases  infections  pregnancy Index. décimale : PER Périodiques Résumé : The aim of this study was to examine potential synergistic effects between maternal autoimmune disease and early childhood infections and their association with autism spectrum disorder (ASD) in offspring. Both exposures have been associated with increased risk of ASD in previous studies, but potential synergistic effects remain underexplored. We conducted a population-based cohort study of singleton children born at term gestation (37-41 weeks) in New South Wales, Australia from January 2002 to December 2008. Maternal autoimmune diagnoses and childhood infections before age 2 years were identified from linked maternal and child hospital admissions, and ASD diagnoses by age 9 years were identified from linked disability services data. Multivariable logistic regression assessed the association between each exposure and ASD and additive interaction between exposures, controlling for potential confounders. A total of 18,451 children exposed to maternal autoimmune disease were propensity score matched (1:2) to 36,902 unexposed children. Any maternal autoimmune disease (adjusted odds ratio (aOR) 1.25, 95% confidence interval (CI) 1.07-1.47) and any childhood infection before age 2 years (aOR 1.38, 95% CI 1.15-1.67) were each associated with ASD. However, there was no evidence of additive interaction between the two exposures (relative excess risk due to interaction [RERI] 0.128, 95% CI -0.418-0.675) resulting in increased odds of ASD in offspring. Future studies could examine potential interactions between other sources of maternal immune activation and childhood infection and impact on ASD and other neurodevelopmental disorders. En ligne : http://dx.doi.org/10.1002/aur.2824 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488

Familial risk and heritability of intellectual disability: a population-based cohort study in Sweden / Paul LICHTENSTEIN in Journal of Child Psychology and Psychiatry, 63-9 (September 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-9 (September 2022) . - p.1092-1102 Titre : Familial risk and heritability of intellectual disability: a population-based cohort study in Sweden Type de document : Texte imprimé et/ou numérique Auteurs : Paul LICHTENSTEIN, Auteur ; Magnus TIDEMAN, Auteur ; Patrick F. SULLIVAN, Auteur ; Eva SERLACHIUS, Auteur ; Henrik LARSSON, Auteur ; Ralf KUJA-HALKOLA, Auteur ; Agnieszka BUTWICKA, Auteur Article en page(s) : p.1092-1102 Langues : Anglais (eng) Mots-clés : Child  Cohort Studies  Genetic Predisposition to Disease  Humans  Intellectual Disability/epidemiology/genetics  Male  Registries  Risk Factors  Sweden/epidemiology  Intellectual disability  family factors  genetics  siblings  twins Index. décimale : PER Périodiques Résumé : BACKGROUND: Intellectual disability (ID) aggregates in families, but factors affecting individual risk and heritability estimates remain unknown. METHODS: A population-based family cohort study of 4,165,785 individuals born 1973-2013 in Sweden, including 37,787 ID individuals and their relatives. The relative risks (RR) of ID with 95% confidence intervals (95% CI) were obtained from stratified Cox proportional-hazards models. Relatives of ID individuals were compared to relatives of unaffected individuals. Structural equation modeling was used to estimate heritability. RESULTS: Relatives of ID individuals were at increased risk of ID compared to individuals with unaffected relatives. The RR of ID among relatives increased proportionally to the degree of genetic relatedness with ID probands; 256.70(95% CI 161.30-408.53) for monozygotic twins, 16.47(13.32-20.38) for parents, 14.88(12.19-18.16) for children, 7.04(4.67-10.61) for dizygotic twins, 8.38(7.97-8.83) for full siblings, 4.56(4.02-5.16) for maternal, 2.90(2.49-3.37) for paternal half-siblings, 3.03(2.61-3.50) for nephews/nieces, 2.84(2.45-3.29) for uncles/aunts, and 2.04(1.91-2.20) for cousins. Lower RRs were observed for siblings of probands with chromosomal abnormalities (RR 5.53, 4.74-6.46) and more severe ID (mild RR 9.15, 8.55-9.78, moderate RR 8.13, 7.28-9.08, severe RR 6.80, 5.74-8.07, and profound RR 5.88, 4.52-7.65). Male sex of relative and maternal line of relationship with proband was related to higher risk (RR 1.33, 1.25-1.41 for brothers vs. sisters and RR 1.49, 1.34-1.68 for maternal vs. paternal half-siblings). ID was substantially heritable with 0.95(95% CI 0.93-0.98) of the variance in liability attributed to genetic influences. CONCLUSIONS: The risk estimates will benefit researchers, clinicians, families in understanding the risk of ID in the family and the whole population. The higher risk of ID related to male sex and maternal linage will be of value for planning and interpreting etiological studies in ID. En ligne : http://dx.doi.org/10.1111/jcpp.13560 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 [article] Familial risk and heritability of intellectual disability: a population-based cohort study in Sweden [Texte imprimé et/ou numérique] / Paul LICHTENSTEIN, Auteur ; Magnus TIDEMAN, Auteur ; Patrick F. SULLIVAN, Auteur ; Eva SERLACHIUS, Auteur ; Henrik LARSSON, Auteur ; Ralf KUJA-HALKOLA, Auteur ; Agnieszka BUTWICKA, Auteur . - p.1092-1102. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-9 (September 2022) . - p.1092-1102 Mots-clés : Child  Cohort Studies  Genetic Predisposition to Disease  Humans  Intellectual Disability/epidemiology/genetics  Male  Registries  Risk Factors  Sweden/epidemiology  Intellectual disability  family factors  genetics  siblings  twins Index. décimale : PER Périodiques Résumé : BACKGROUND: Intellectual disability (ID) aggregates in families, but factors affecting individual risk and heritability estimates remain unknown. METHODS: A population-based family cohort study of 4,165,785 individuals born 1973-2013 in Sweden, including 37,787 ID individuals and their relatives. The relative risks (RR) of ID with 95% confidence intervals (95% CI) were obtained from stratified Cox proportional-hazards models. Relatives of ID individuals were compared to relatives of unaffected individuals. Structural equation modeling was used to estimate heritability. RESULTS: Relatives of ID individuals were at increased risk of ID compared to individuals with unaffected relatives. The RR of ID among relatives increased proportionally to the degree of genetic relatedness with ID probands; 256.70(95% CI 161.30-408.53) for monozygotic twins, 16.47(13.32-20.38) for parents, 14.88(12.19-18.16) for children, 7.04(4.67-10.61) for dizygotic twins, 8.38(7.97-8.83) for full siblings, 4.56(4.02-5.16) for maternal, 2.90(2.49-3.37) for paternal half-siblings, 3.03(2.61-3.50) for nephews/nieces, 2.84(2.45-3.29) for uncles/aunts, and 2.04(1.91-2.20) for cousins. Lower RRs were observed for siblings of probands with chromosomal abnormalities (RR 5.53, 4.74-6.46) and more severe ID (mild RR 9.15, 8.55-9.78, moderate RR 8.13, 7.28-9.08, severe RR 6.80, 5.74-8.07, and profound RR 5.88, 4.52-7.65). Male sex of relative and maternal line of relationship with proband was related to higher risk (RR 1.33, 1.25-1.41 for brothers vs. sisters and RR 1.49, 1.34-1.68 for maternal vs. paternal half-siblings). ID was substantially heritable with 0.95(95% CI 0.93-0.98) of the variance in liability attributed to genetic influences. CONCLUSIONS: The risk estimates will benefit researchers, clinicians, families in understanding the risk of ID in the family and the whole population. The higher risk of ID related to male sex and maternal linage will be of value for planning and interpreting etiological studies in ID. En ligne : http://dx.doi.org/10.1111/jcpp.13560 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486

Parental socioeconomic position and risk of autism spectrum disorders in offspring: A cohort study of 9,648 individuals in Denmark 1976-2013 / Emilie Rune HEGELUND in Research in Autism Spectrum Disorders, 56 (December 2018)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 56 (December 2018) . - p.1-8 Titre : Parental socioeconomic position and risk of autism spectrum disorders in offspring: A cohort study of 9,648 individuals in Denmark 1976-2013 Type de document : Texte imprimé et/ou numérique Auteurs : Emilie Rune HEGELUND, Auteur ; Trine FLENSBORG-MADSEN, Auteur ; Ditte VASSARD, Auteur ; Leonard A. ROSENBLUM, Auteur ; June Machover REINISCH, Auteur ; Erik Lykke MORTENSEN, Auteur Article en page(s) : p.1-8 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Socioeconomic factors  Cohort studies  Denmark Index. décimale : PER Périodiques Résumé : Background The results of studies of the association between parental socioeconomic position (SEP) and risk of autism spectrum disorder (ASD) in offspring are inconsistent, perhaps due to contextual differences in health care systems and their influence on risk of ASD diagnosis among different socioeconomic groups. The present study investigated the association between parental SEP in adulthood and risk of ASD diagnosis in offspring in a Nordic welfare state and whether this association was modified by parental childhood SEP. Method The study population comprised 9648 live-born singletons who were followed in the Psychiatric Central Register from birth in 1976–1996 until 2013. Cox regression was used to estimate hazard ratios for ASD diagnosis according to parental SEP in adulthood. Results The crude results showed a tendency towards higher parental SEP in adulthood being associated with higher risk of ASD diagnosis in offspring. However, the association was reversed after adjustment for possible confounders. The reversion of the direction of the association was entirely attributable to the strong confounding effect of calendar year. Further, the results showed that parental childhood SEP modified the association between parental SEP in adulthood and risk of ASD diagnosis in offspring. Conclusions Both methodological and contextual issues may be of great importance for the observed association between parental SEP and risk of ASD diagnosis in offspring. Particularly, the secular trends in ASD diagnoses seem to be of great importance suggesting that changes in diagnostic patterns may influence the association between parental SEP and risk of being diagnosed with ASD. En ligne : https://doi.org/10.1016/j.rasd.2018.08.004 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=369 [article] Parental socioeconomic position and risk of autism spectrum disorders in offspring: A cohort study of 9,648 individuals in Denmark 1976-2013 [Texte imprimé et/ou numérique] / Emilie Rune HEGELUND, Auteur ; Trine FLENSBORG-MADSEN, Auteur ; Ditte VASSARD, Auteur ; Leonard A. ROSENBLUM, Auteur ; June Machover REINISCH, Auteur ; Erik Lykke MORTENSEN, Auteur . - p.1-8. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 56 (December 2018) . - p.1-8 Mots-clés : Autism spectrum disorder  Socioeconomic factors  Cohort studies  Denmark Index. décimale : PER Périodiques Résumé : Background The results of studies of the association between parental socioeconomic position (SEP) and risk of autism spectrum disorder (ASD) in offspring are inconsistent, perhaps due to contextual differences in health care systems and their influence on risk of ASD diagnosis among different socioeconomic groups. The present study investigated the association between parental SEP in adulthood and risk of ASD diagnosis in offspring in a Nordic welfare state and whether this association was modified by parental childhood SEP. Method The study population comprised 9648 live-born singletons who were followed in the Psychiatric Central Register from birth in 1976–1996 until 2013. Cox regression was used to estimate hazard ratios for ASD diagnosis according to parental SEP in adulthood. Results The crude results showed a tendency towards higher parental SEP in adulthood being associated with higher risk of ASD diagnosis in offspring. However, the association was reversed after adjustment for possible confounders. The reversion of the direction of the association was entirely attributable to the strong confounding effect of calendar year. Further, the results showed that parental childhood SEP modified the association between parental SEP in adulthood and risk of ASD diagnosis in offspring. Conclusions Both methodological and contextual issues may be of great importance for the observed association between parental SEP and risk of ASD diagnosis in offspring. Particularly, the secular trends in ASD diagnoses seem to be of great importance suggesting that changes in diagnostic patterns may influence the association between parental SEP and risk of being diagnosed with ASD. En ligne : https://doi.org/10.1016/j.rasd.2018.08.004 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=369

Premature mortality in a population-based cohort of autistic adults in Canada / Yona LUNSKY in Autism Research, 15-8 (August 2022)  

Public ISBD [article]  inAutism Research > 15-8 (August 2022) . - p.1550-1559 Titre : Premature mortality in a population-based cohort of autistic adults in Canada Type de document : Texte imprimé et/ou numérique Auteurs : Yona LUNSKY, Auteur ; Meng-Chuan LAI, Auteur ; Robert BALOGH, Auteur ; Hannah CHUNG, Auteur ; Anna DURBIN, Auteur ; Patrick JACHYRA, Auteur ; Ami TINT, Auteur ; Jonathan WEISS, Auteur ; Elizabeth LIN, Auteur Article en page(s) : p.1550-1559 Langues : Anglais (eng) Mots-clés : Adult  Autism Spectrum Disorder/epidemiology  Autistic Disorder/epidemiology  Child  Cohort Studies  Developmental Disabilities/epidemiology  Female  Humans  Infant, Newborn  Male  Mortality, Premature  Ontario/epidemiology  autism  developmental disabilities  premature mortality  sex differences Index. décimale : PER Périodiques Résumé : Research from different countries suggests that autistic adults are more likely to die prematurely than non-autistic adults, but these studies do not always investigate male and female individuals separately and do not consider whether this pattern is unique to autistic people or is also an issue for people with other developmental disabilities. We examined premature mortality in autistic males and females (assigned at birth) in a population-based cohort, compared to males and females with and without other developmental disabilities. Using linked administrative health and social services population data from Ontario, Canada, age-matched males and females aged 19-65years were followed between 2010 and 2016, and causes of death were determined. Over the 6-year observation period, 330 of 42,607 persons (0.77%) in the group without developmental disabilities had died compared to 259 of 10,646 persons (2.43%) in the autism group and 419 of 10,615 persons (3.95%) in the other developmental disabilities group. Autistic males and females were more likely to die than non-autistic males (adjusted risk ratio, RR 3.13, 95%CI 2.58-3.79) and non-autistic females (adjusted RR 3.12, 95%CI 2.35-4.13) without developmental disabilities, but were less likely to die than adults with other developmental disabilities (males: adjusted RR 0.66, 95%CI 0.55-0.79; females: adjusted RR 0.55, 95%CI 0.43-0.71). Most common causes of death varied depending on a person's sex and diagnosis. Given the greater likelihood of premature mortality in adults with developmental disabilities including autism, greater attention and resources directed toward their health and social care are needed, tailored to their sex and diagnosis-informed needs. LAY SUMMARY: This study looked at how many autistic men and women died over 6years (2010-2016), along with how they died, and compared this to adults who did not have autism living in Ontario, Canada. It found that autistic men and women were more than three times as likely to die as people of the same age who did not have a developmental disability. However, adults with other developmental disabilities besides autism were even more likely to die than autistic adults. This means that we have to pay more attention and invest in better social and health care for autistic people, along with people who have other types of developmental disabilities. En ligne : http://dx.doi.org/10.1002/aur.2741 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=483 [article] Premature mortality in a population-based cohort of autistic adults in Canada [Texte imprimé et/ou numérique] / Yona LUNSKY, Auteur ; Meng-Chuan LAI, Auteur ; Robert BALOGH, Auteur ; Hannah CHUNG, Auteur ; Anna DURBIN, Auteur ; Patrick JACHYRA, Auteur ; Ami TINT, Auteur ; Jonathan WEISS, Auteur ; Elizabeth LIN, Auteur . - p.1550-1559. Langues : Anglais (eng) in Autism Research > 15-8 (August 2022) . - p.1550-1559 Mots-clés : Adult  Autism Spectrum Disorder/epidemiology  Autistic Disorder/epidemiology  Child  Cohort Studies  Developmental Disabilities/epidemiology  Female  Humans  Infant, Newborn  Male  Mortality, Premature  Ontario/epidemiology  autism  developmental disabilities  premature mortality  sex differences Index. décimale : PER Périodiques Résumé : Research from different countries suggests that autistic adults are more likely to die prematurely than non-autistic adults, but these studies do not always investigate male and female individuals separately and do not consider whether this pattern is unique to autistic people or is also an issue for people with other developmental disabilities. We examined premature mortality in autistic males and females (assigned at birth) in a population-based cohort, compared to males and females with and without other developmental disabilities. Using linked administrative health and social services population data from Ontario, Canada, age-matched males and females aged 19-65years were followed between 2010 and 2016, and causes of death were determined. Over the 6-year observation period, 330 of 42,607 persons (0.77%) in the group without developmental disabilities had died compared to 259 of 10,646 persons (2.43%) in the autism group and 419 of 10,615 persons (3.95%) in the other developmental disabilities group. Autistic males and females were more likely to die than non-autistic males (adjusted risk ratio, RR 3.13, 95%CI 2.58-3.79) and non-autistic females (adjusted RR 3.12, 95%CI 2.35-4.13) without developmental disabilities, but were less likely to die than adults with other developmental disabilities (males: adjusted RR 0.66, 95%CI 0.55-0.79; females: adjusted RR 0.55, 95%CI 0.43-0.71). Most common causes of death varied depending on a person's sex and diagnosis. Given the greater likelihood of premature mortality in adults with developmental disabilities including autism, greater attention and resources directed toward their health and social care are needed, tailored to their sex and diagnosis-informed needs. LAY SUMMARY: This study looked at how many autistic men and women died over 6years (2010-2016), along with how they died, and compared this to adults who did not have autism living in Ontario, Canada. It found that autistic men and women were more than three times as likely to die as people of the same age who did not have a developmental disability. However, adults with other developmental disabilities besides autism were even more likely to die than autistic adults. This means that we have to pay more attention and invest in better social and health care for autistic people, along with people who have other types of developmental disabilities. En ligne : http://dx.doi.org/10.1002/aur.2741 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=483

Sex, ethnic and socioeconomic inequalities and trajectories in child and adolescent mental health in Australia and the UK: findings from national prospective longitudinal studies / S. TERHAAG in Journal of Child Psychology and Psychiatry, 62-10 (October 2021)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 62-10 (October 2021) . - p.1255-1267 Titre : Sex, ethnic and socioeconomic inequalities and trajectories in child and adolescent mental health in Australia and the UK: findings from national prospective longitudinal studies Type de document : Texte imprimé et/ou numérique Auteurs : S. TERHAAG, Auteur ; E. FITZSIMONS, Auteur ; G. DARAGANOVA, Auteur ; Praveetha PATALAY, Auteur Article en page(s) : p.1255-1267 Langues : Anglais (eng) Mots-clés : Adolescent  Australia/epidemiology  Child  Child, Preschool  Cohort Studies  Ethnicity  Female  Humans  Longitudinal Studies  Male  Mental Health  Minority Groups  Prospective Studies  Socioeconomic Factors  United Kingdom/epidemiology  disadvantage  inequality  internalising  young people Index. décimale : PER Périodiques Résumé : BACKGROUND: This study investigates the sex, ethnic and socioeconomic inequalities in emotional difficulties over childhood and adolescence using longitudinal cohort studies in the UK and Australia. Estimating cross-national differences contributes to understanding of the consistency of inequalities in mental health across contexts. METHODS: Data from 19,748 participants in two contemporary representative samples in Australia (Growing Up in Australia: The Longitudinal Study of Australian Children, n = 4,975) and UK (Millennium Cohort Study, n = 14,773) were used. Emotional difficulties were assessed using the parent-reported Strengths and Difficulties Questionnaire at ages 4/5, 6/7, 11/12 and 14/15 years and the self-reported Short Moods and Feelings Questionnaire at age 14/15. Latent Growth Curve Modelling was used to examine mental health over time. RESULTS: There were significant increases in emotional difficulties in both countries over time. Emotional difficulties were higher in Australian children at all ages. The gender gap in self-reported depressive symptoms at age 14/15 was larger in the UK (8% of UK and 13% of Australian boys were above the depression cut-off, compared with 23% of girls). Ethnic minority children had higher emotional difficulties at age 4/5 years in both countries, but over time this difference was no longer observed in Australia. In the UK, this reversed whereby at ages 11/12 and 14/15 ethnic minority children had lower symptoms than their White majority peers. Socioeconomic differences were more marked based on parent education and employment status in Australia and by parent income in the UK. UK children, children from White majority ethnicity and girls evidenced steeper worsening of symptoms from age 4/5 to 14/15 years. CONCLUSIONS: Even in two fairly similar countries (i.e. English-speaking, high-income, industrialised), the observed patterns of inequalities in mental health symptoms based on sociodemographics are not the same. Understanding country and context-specific drivers of different inequalities provides important insights to help reduce disparities in child and adolescent mental health. En ligne : http://dx.doi.org/10.1111/jcpp.13410 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456 [article] Sex, ethnic and socioeconomic inequalities and trajectories in child and adolescent mental health in Australia and the UK: findings from national prospective longitudinal studies [Texte imprimé et/ou numérique] / S. TERHAAG, Auteur ; E. FITZSIMONS, Auteur ; G. DARAGANOVA, Auteur ; Praveetha PATALAY, Auteur . - p.1255-1267. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 62-10 (October 2021) . - p.1255-1267 Mots-clés : Adolescent  Australia/epidemiology  Child  Child, Preschool  Cohort Studies  Ethnicity  Female  Humans  Longitudinal Studies  Male  Mental Health  Minority Groups  Prospective Studies  Socioeconomic Factors  United Kingdom/epidemiology  disadvantage  inequality  internalising  young people Index. décimale : PER Périodiques Résumé : BACKGROUND: This study investigates the sex, ethnic and socioeconomic inequalities in emotional difficulties over childhood and adolescence using longitudinal cohort studies in the UK and Australia. Estimating cross-national differences contributes to understanding of the consistency of inequalities in mental health across contexts. METHODS: Data from 19,748 participants in two contemporary representative samples in Australia (Growing Up in Australia: The Longitudinal Study of Australian Children, n = 4,975) and UK (Millennium Cohort Study, n = 14,773) were used. Emotional difficulties were assessed using the parent-reported Strengths and Difficulties Questionnaire at ages 4/5, 6/7, 11/12 and 14/15 years and the self-reported Short Moods and Feelings Questionnaire at age 14/15. Latent Growth Curve Modelling was used to examine mental health over time. RESULTS: There were significant increases in emotional difficulties in both countries over time. Emotional difficulties were higher in Australian children at all ages. The gender gap in self-reported depressive symptoms at age 14/15 was larger in the UK (8% of UK and 13% of Australian boys were above the depression cut-off, compared with 23% of girls). Ethnic minority children had higher emotional difficulties at age 4/5 years in both countries, but over time this difference was no longer observed in Australia. In the UK, this reversed whereby at ages 11/12 and 14/15 ethnic minority children had lower symptoms than their White majority peers. Socioeconomic differences were more marked based on parent education and employment status in Australia and by parent income in the UK. UK children, children from White majority ethnicity and girls evidenced steeper worsening of symptoms from age 4/5 to 14/15 years. CONCLUSIONS: Even in two fairly similar countries (i.e. English-speaking, high-income, industrialised), the observed patterns of inequalities in mental health symptoms based on sociodemographics are not the same. Understanding country and context-specific drivers of different inequalities provides important insights to help reduce disparities in child and adolescent mental health. En ligne : http://dx.doi.org/10.1111/jcpp.13410 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456

Shared familial risk factors between autism spectrum disorder and obesity - a register-based familial coaggregation cohort study / Richard AHLBERG in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)  

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Twenty-year longitudinal birth cohort study of individuals diagnosed with autism spectrum disorder before seven years of age / Mitsuaki IWASA in Journal of Child Psychology and Psychiatry, 63-12 (December 2022)  

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Validation of Autism Diagnosis and Clinical Data in the SPARK Cohort / Eric FOMBONNE in Journal of Autism and Developmental Disorders, 52-8 (August 2022)  

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Adverse clinical outcomes among youths with nonsuicidal self-injury and suicide attempts: a longitudinal cohort study / Johan BJUREBERG in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)  

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Antipsychotic Medication and Risk of Incident Seizure in People with Autism Spectrum Disorder: Analyses with Cohort and Within Individual Study Designs / Basmah H. ALFAGEH in Journal of Autism and Developmental Disorders, 52-11 (November 2022)  

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