Amygdala Volume Differences in Autism Spectrum Disorder Are Related to Anxiety / John D. HERRINGTON in Journal of Autism and Developmental Disorders, 47-12 (December 2017)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 47-12 (December 2017) . - p.3682-3691 Titre : Amygdala Volume Differences in Autism Spectrum Disorder Are Related to Anxiety Type de document : texte imprimé Auteurs : John D. HERRINGTON, Auteur ; Brenna B. MADDOX, Auteur ; Connor M. KERNS, Auteur ; Keiran M. RUMP, Auteur ; Julie A. WORLEY, Auteur ; Jennifer C. BUSH, Auteur ; Alana J. MCVEY, Auteur ; Robert T. SCHULTZ, Auteur ; Judith S. MILLER, Auteur Année de publication : 2017 Article en page(s) : p.3682-3691 Langues : Anglais (eng) Mots-clés : Amygdala  Anxiety disorders  Brain morphometry  Comorbidity Index. décimale : PER Périodiques Résumé : Recent studies suggest that longstanding findings of abnormal amygdala morphology in ASD may be related to symptoms of anxiety. To test this hypothesis, fifty-three children with ASD (mean age = 11.9) underwent structural MRI and were divided into subgroups to compare those with at least one anxiety disorder diagnosis (n = 29) to those without (n = 24) and to a typically developing control group (TDC; n = 37). Groups were matched on age and intellectual level. The ASD and anxiety group showed decreased right amygdala volume (controlled for total brain volume) relative to ASD without anxiety (p = .04) and TDCs (p = .068). Results suggest that youth with ASD and co-occurring anxiety have a distinct neurodevelopmental trajectory. En ligne : http://dx.doi.org/10.1007/s10803-017-3206-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=325 [article] Amygdala Volume Differences in Autism Spectrum Disorder Are Related to Anxiety [texte imprimé] / John D. HERRINGTON, Auteur ; Brenna B. MADDOX, Auteur ; Connor M. KERNS, Auteur ; Keiran M. RUMP, Auteur ; Julie A. WORLEY, Auteur ; Jennifer C. BUSH, Auteur ; Alana J. MCVEY, Auteur ; Robert T. SCHULTZ, Auteur ; Judith S. MILLER, Auteur . - 2017 . - p.3682-3691. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 47-12 (December 2017) . - p.3682-3691 Mots-clés : Amygdala  Anxiety disorders  Brain morphometry  Comorbidity Index. décimale : PER Périodiques Résumé : Recent studies suggest that longstanding findings of abnormal amygdala morphology in ASD may be related to symptoms of anxiety. To test this hypothesis, fifty-three children with ASD (mean age = 11.9) underwent structural MRI and were divided into subgroups to compare those with at least one anxiety disorder diagnosis (n = 29) to those without (n = 24) and to a typically developing control group (TDC; n = 37). Groups were matched on age and intellectual level. The ASD and anxiety group showed decreased right amygdala volume (controlled for total brain volume) relative to ASD without anxiety (p = .04) and TDCs (p = .068). Results suggest that youth with ASD and co-occurring anxiety have a distinct neurodevelopmental trajectory. En ligne : http://dx.doi.org/10.1007/s10803-017-3206-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=325

Brief measures of anxiety in non-treatment-seeking youth with autism spectrum disorder / Connor M. KERNS in Autism, 19-8 (November 2015)  

Public ISBD [article]  inAutism > 19-8 (November 2015) . - p.969-979 Titre : Brief measures of anxiety in non-treatment-seeking youth with autism spectrum disorder Type de document : texte imprimé Auteurs : Connor M. KERNS, Auteur ; Brenna B. MADDOX, Auteur ; Philip C. KENDALL, Auteur ; Keiran M. RUMP, Auteur ; Leandra N. BERRY, Auteur ; Robert T. SCHULTZ, Auteur ; Margaret C. SOUDERS, Auteur ; Amanda E. BENNETT, Auteur ; John D. HERRINGTON, Auteur ; Judith MILLER, Auteur Article en page(s) : p.969-979 Langues : Anglais (eng) Mots-clés : adolescent  anxiety  child  measures  sensitivity  specificity Index. décimale : PER Périodiques Résumé : This study investigated the accuracy of brief anxiety scales for non-treatment-seeking youth with autism spectrum disorder. In all, 54 youth (7–17 years; IQ: 67–158) with autism spectrum disorder and their parents completed (a) an expanded version of the Anxiety Disorders Interview Schedule—Child/Parent designed to capture typical and atypical fears and (b) brief scales of anxiety symptoms (Behavior Assessment Schedule for Children, Second Edition; Screen for Child Anxiety and Related Emotional Disorders; Negative Affective Self-Statement Questionnaire; Pediatric Anxiety Rating Scale). The results indicate that measures lacked adequate sensitivity and specificity, and the detection of atypical fears was particularly poor. Revised cut scores are offered, but refined and/or revised instruments are likely needed for research on youth with autism spectrum disorder. En ligne : http://dx.doi.org/10.1177/1362361314558465 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=269 [article] Brief measures of anxiety in non-treatment-seeking youth with autism spectrum disorder [texte imprimé] / Connor M. KERNS, Auteur ; Brenna B. MADDOX, Auteur ; Philip C. KENDALL, Auteur ; Keiran M. RUMP, Auteur ; Leandra N. BERRY, Auteur ; Robert T. SCHULTZ, Auteur ; Margaret C. SOUDERS, Auteur ; Amanda E. BENNETT, Auteur ; John D. HERRINGTON, Auteur ; Judith MILLER, Auteur . - p.969-979. Langues : Anglais (eng) in Autism > 19-8 (November 2015) . - p.969-979 Mots-clés : adolescent  anxiety  child  measures  sensitivity  specificity Index. décimale : PER Périodiques Résumé : This study investigated the accuracy of brief anxiety scales for non-treatment-seeking youth with autism spectrum disorder. In all, 54 youth (7–17 years; IQ: 67–158) with autism spectrum disorder and their parents completed (a) an expanded version of the Anxiety Disorders Interview Schedule—Child/Parent designed to capture typical and atypical fears and (b) brief scales of anxiety symptoms (Behavior Assessment Schedule for Children, Second Edition; Screen for Child Anxiety and Related Emotional Disorders; Negative Affective Self-Statement Questionnaire; Pediatric Anxiety Rating Scale). The results indicate that measures lacked adequate sensitivity and specificity, and the detection of atypical fears was particularly poor. Revised cut scores are offered, but refined and/or revised instruments are likely needed for research on youth with autism spectrum disorder. En ligne : http://dx.doi.org/10.1177/1362361314558465 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=269

Do Student Characteristics Affect Teachers' Decisions to Use 1:1 Instruction? / Heather J. NUSKE in Journal of Autism and Developmental Disorders, 49-7 (July 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-7 (July 2019) . - p.2864-2872 Titre : Do Student Characteristics Affect Teachers' Decisions to Use 1:1 Instruction? Type de document : texte imprimé Auteurs : Heather J. NUSKE, Auteur ; Melanie PELLECCHIA, Auteur ; Victor LUSHIN, Auteur ; Keiran M. RUMP, Auteur ; Max SEIDMAN, Auteur ; Rachel R. OUELLETTE, Auteur ; Diana COONEY, Auteur ; Brenna B. MADDOX, Auteur ; Gwendolyn M. LAWSON, Auteur ; Amber SONG, Auteur ; Erica M. REISINGER, Auteur ; David S. MANDELL, Auteur Article en page(s) : p.2864-2872 Langues : Anglais (eng) Mots-clés : 1:1 Instruction  Child characteristics  Personalized medicine  Teacher decisions Index. décimale : PER Périodiques Résumé : One-to-one instruction is a critical component of evidence-based instruction for students with autism spectrum disorder, but is not used as often as recommended. Student characteristics may affect teachers' decisions to select a treatment and/or implement it. This study examined the associations between students' clinical and demographic characteristics and teachers' reported use of discrete trial training (DTT) and pivotal response training (PRT). Children's higher sensory symptoms, lower social approach, lower verbal skills and higher self-regulation difficulties were associated with more frequent 1:1 DTT and PRT. Results suggest that teachers give more frequent 1:1 instruction to children with more observable impairments, do not match children to type of 1:1 intervention, and may inadvertently neglect other students for whom individualized intervention may still be beneficial. En ligne : http://dx.doi.org/10.1007/s10803-019-04004-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402 [article] Do Student Characteristics Affect Teachers' Decisions to Use 1:1 Instruction? [texte imprimé] / Heather J. NUSKE, Auteur ; Melanie PELLECCHIA, Auteur ; Victor LUSHIN, Auteur ; Keiran M. RUMP, Auteur ; Max SEIDMAN, Auteur ; Rachel R. OUELLETTE, Auteur ; Diana COONEY, Auteur ; Brenna B. MADDOX, Auteur ; Gwendolyn M. LAWSON, Auteur ; Amber SONG, Auteur ; Erica M. REISINGER, Auteur ; David S. MANDELL, Auteur . - p.2864-2872. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-7 (July 2019) . - p.2864-2872 Mots-clés : 1:1 Instruction  Child characteristics  Personalized medicine  Teacher decisions Index. décimale : PER Périodiques Résumé : One-to-one instruction is a critical component of evidence-based instruction for students with autism spectrum disorder, but is not used as often as recommended. Student characteristics may affect teachers' decisions to select a treatment and/or implement it. This study examined the associations between students' clinical and demographic characteristics and teachers' reported use of discrete trial training (DTT) and pivotal response training (PRT). Children's higher sensory symptoms, lower social approach, lower verbal skills and higher self-regulation difficulties were associated with more frequent 1:1 DTT and PRT. Results suggest that teachers give more frequent 1:1 instruction to children with more observable impairments, do not match children to type of 1:1 intervention, and may inadvertently neglect other students for whom individualized intervention may still be beneficial. En ligne : http://dx.doi.org/10.1007/s10803-019-04004-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402

Measuring social attention and motivation in autism spectrum disorder using eye-tracking: Stimulus type matters / Coralie CHEVALLIER in Autism Research, 8-5 (October 2015)  

Public ISBD [article]  inAutism Research > 8-5 (October 2015) . - p.620-628 Titre : Measuring social attention and motivation in autism spectrum disorder using eye-tracking: Stimulus type matters Type de document : texte imprimé Auteurs : Coralie CHEVALLIER, Auteur ; Julia PARISH-MORRIS, Auteur ; Alana J. MCVEY, Auteur ; Keiran M. RUMP, Auteur ; Noah J. SASSON, Auteur ; John D. HERRINGTON, Auteur ; Robert T. SCHULTZ, Auteur Article en page(s) : p.620-628 Langues : Anglais (eng) Mots-clés : social attention  autism spectrum disorder  eye-tracking  social motivation  methodology  face processing Index. décimale : PER Périodiques Résumé : Autism Spectrum Disorder (ASD) is characterized by social impairments that have been related to deficits in social attention, including diminished gaze to faces. Eye-tracking studies are commonly used to examine social attention and social motivation in ASD, but they vary in sensitivity. In this study, we hypothesized that the ecological nature of the social stimuli would affect participants' social attention, with gaze behavior during more naturalistic scenes being most predictive of ASD vs. typical development. Eighty-one children with and without ASD participated in three eye-tracking tasks that differed in the ecological relevance of the social stimuli. In the “Static Visual Exploration” task, static images of objects and people were presented; in the “Dynamic Visual Exploration” task, video clips of individual faces and objects were presented side-by-side; in the “Interactive Visual Exploration” task, video clips of children playing with objects in a naturalistic context were presented. Our analyses uncovered a three-way interaction between Task, Social vs. Object Stimuli, and Diagnosis. This interaction was driven by group differences on one task only—the Interactive task. Bayesian analyses confirmed that the other two tasks were insensitive to group membership. In addition, receiver operating characteristic analyses demonstrated that, unlike the other two tasks, the Interactive task had significant classification power. The ecological relevance of social stimuli is an important factor to consider for eye-tracking studies aiming to measure social attention and motivation in ASD. Autism Res 2015, 8: 620–628. © 2015 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1479 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=270 [article] Measuring social attention and motivation in autism spectrum disorder using eye-tracking: Stimulus type matters [texte imprimé] / Coralie CHEVALLIER, Auteur ; Julia PARISH-MORRIS, Auteur ; Alana J. MCVEY, Auteur ; Keiran M. RUMP, Auteur ; Noah J. SASSON, Auteur ; John D. HERRINGTON, Auteur ; Robert T. SCHULTZ, Auteur . - p.620-628. Langues : Anglais (eng) in Autism Research > 8-5 (October 2015) . - p.620-628 Mots-clés : social attention  autism spectrum disorder  eye-tracking  social motivation  methodology  face processing Index. décimale : PER Périodiques Résumé : Autism Spectrum Disorder (ASD) is characterized by social impairments that have been related to deficits in social attention, including diminished gaze to faces. Eye-tracking studies are commonly used to examine social attention and social motivation in ASD, but they vary in sensitivity. In this study, we hypothesized that the ecological nature of the social stimuli would affect participants' social attention, with gaze behavior during more naturalistic scenes being most predictive of ASD vs. typical development. Eighty-one children with and without ASD participated in three eye-tracking tasks that differed in the ecological relevance of the social stimuli. In the “Static Visual Exploration” task, static images of objects and people were presented; in the “Dynamic Visual Exploration” task, video clips of individual faces and objects were presented side-by-side; in the “Interactive Visual Exploration” task, video clips of children playing with objects in a naturalistic context were presented. Our analyses uncovered a three-way interaction between Task, Social vs. Object Stimuli, and Diagnosis. This interaction was driven by group differences on one task only—the Interactive task. Bayesian analyses confirmed that the other two tasks were insensitive to group membership. In addition, receiver operating characteristic analyses demonstrated that, unlike the other two tasks, the Interactive task had significant classification power. The ecological relevance of social stimuli is an important factor to consider for eye-tracking studies aiming to measure social attention and motivation in ASD. Autism Res 2015, 8: 620–628. © 2015 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1479 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=270

Profiles of Autonomic Activity in Autism Spectrum Disorder with and without Anxiety / Valentina PARMA in Journal of Autism and Developmental Disorders, 51-12 (December 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-12 (December 2021) . - p.4459-4470 Titre : Profiles of Autonomic Activity in Autism Spectrum Disorder with and without Anxiety Type de document : texte imprimé Auteurs : Valentina PARMA, Auteur ; Nicola CELLINI, Auteur ; Lisa GUY, Auteur ; Alana J. MCVEY, Auteur ; Keiran M. RUMP, Auteur ; Julie WORLEY, Auteur ; Brenna B. MADDOX, Auteur ; Jennifer BUSH, Auteur ; Amanda E. BENNETT, Auteur ; Martin FRANKLIN, Auteur ; Judith S. MILLER, Auteur ; John D. HERRINGTON, Auteur Article en page(s) : p.4459-4470 Langues : Anglais (eng) Mots-clés : Adolescent  Anxiety  Anxiety Disorders/epidemiology  Autism Spectrum Disorder  Autonomic Nervous System  Child  Humans  Anxiety disorder  Autism spectrum disorder  Autonomic profile  Electrodermal activity  Heart rate variability Index. décimale : PER Périodiques Résumé : Both anxiety and autism spectrum disorder (ASD) are associated with atypical physiological activity. Few studies have systematically assessed the resting physiological activity in ASD with co-occurring anxiety disorders. We tested 75 participants divided in four groups: youth with ASD, with (ASD + Anxiety = 22, 6F, 12.29 ± 2.83 years old) and without co-occurring anxiety (ASD Alone = 15, 6F, 11.59 ± 2.85 years old) and compared their physiological profile with that of matched typically developing controls (TDC) with (Anxiety Alone = 16, 6F, 11.24 ± 3.36 years old) and without co-occurring anxiety disorders (TDC = 22, 8F, 11.88 ± 2.88 years old). Results indicated reduced sympathetic and parasympathetic activity at rest in ASD as compared to TDC youth. ASD + Anxiety and Anxiety Alone groups showed different sympathetic, but similar parasympathetic activity. These findings suggest that autonomic profile-based approaches may advance research, diagnosis, and treatment of ASD and anxiety. En ligne : http://dx.doi.org/10.1007/s10803-020-04862-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454 [article] Profiles of Autonomic Activity in Autism Spectrum Disorder with and without Anxiety [texte imprimé] / Valentina PARMA, Auteur ; Nicola CELLINI, Auteur ; Lisa GUY, Auteur ; Alana J. MCVEY, Auteur ; Keiran M. RUMP, Auteur ; Julie WORLEY, Auteur ; Brenna B. MADDOX, Auteur ; Jennifer BUSH, Auteur ; Amanda E. BENNETT, Auteur ; Martin FRANKLIN, Auteur ; Judith S. MILLER, Auteur ; John D. HERRINGTON, Auteur . - p.4459-4470. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-12 (December 2021) . - p.4459-4470 Mots-clés : Adolescent  Anxiety  Anxiety Disorders/epidemiology  Autism Spectrum Disorder  Autonomic Nervous System  Child  Humans  Anxiety disorder  Autism spectrum disorder  Autonomic profile  Electrodermal activity  Heart rate variability Index. décimale : PER Périodiques Résumé : Both anxiety and autism spectrum disorder (ASD) are associated with atypical physiological activity. Few studies have systematically assessed the resting physiological activity in ASD with co-occurring anxiety disorders. We tested 75 participants divided in four groups: youth with ASD, with (ASD + Anxiety = 22, 6F, 12.29 ± 2.83 years old) and without co-occurring anxiety (ASD Alone = 15, 6F, 11.59 ± 2.85 years old) and compared their physiological profile with that of matched typically developing controls (TDC) with (Anxiety Alone = 16, 6F, 11.24 ± 3.36 years old) and without co-occurring anxiety disorders (TDC = 22, 8F, 11.88 ± 2.88 years old). Results indicated reduced sympathetic and parasympathetic activity at rest in ASD as compared to TDC youth. ASD + Anxiety and Anxiety Alone groups showed different sympathetic, but similar parasympathetic activity. These findings suggest that autonomic profile-based approaches may advance research, diagnosis, and treatment of ASD and anxiety. En ligne : http://dx.doi.org/10.1007/s10803-020-04862-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454

Prototype formation in autism: Can individuals with autism abstract facial prototypes? / Holly ZAJAC GASTGEB in Autism Research, 2-5 (October 2009)  

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