Dépouillements

Challenges encountered with a mindfulness app: Lessons learnt from a pilot randomized trial involving caregivers and individuals with autism / Matthew HARTLEY in Research in Autism Spectrum Disorders, 96 (August 2022)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 96 (August 2022) . - 101991 Titre : Challenges encountered with a mindfulness app: Lessons learnt from a pilot randomized trial involving caregivers and individuals with autism Type de document : Texte imprimé et/ou numérique Auteurs : Matthew HARTLEY, Auteur ; Diana S. DORSTYN, Auteur ; Clemence DUE, Auteur Article en page(s) : 101991 Langues : Anglais (eng) Mots-clés : Smartphone  Parents  Mindfulness  Children  Autism Index. décimale : PER Périodiques Résumé : Background We undertook a trial to examine the feasibility of a self-guided mindfulness app, Smiling Mind, for children and adults with Autism Spectrum Disorder (ASD) and their parents. The trial encountered problems in recruitment, enrollment and retention which are described here. Methods : Of 169 eligible participants, only 22 consented and were randomly assigned to Smiling Mind (n = 12) or an attention control condition (n = 10). A further six participants withdrew during the study. Barriers to trial participation were subsequently explored through semi-structured interviews, to form case studies, and a follow-up survey. Results Interview and survey data highlighted parents? competing time commitments as a key barrier to participation. For children and adults with ASD, distraction and boredom were major challenges to engagement. Conclusions A number of modifiable variables in our recruitment procedures and intervention design ultimately resulted in a sample size that was too small to draw any firm conclusions from. Future ASD research can maximize sampling by broadening recruitment strategies and partnering with community services and schools. Engagement in mindfulness could also be improved by incorporating regular communication to motivate time poor participants. En ligne : https://doi.org/10.1016/j.rasd.2022.101991 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480 [article] Challenges encountered with a mindfulness app: Lessons learnt from a pilot randomized trial involving caregivers and individuals with autism [Texte imprimé et/ou numérique] / Matthew HARTLEY, Auteur ; Diana S. DORSTYN, Auteur ; Clemence DUE, Auteur . - 101991. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 96 (August 2022) . - 101991 Mots-clés : Smartphone  Parents  Mindfulness  Children  Autism Index. décimale : PER Périodiques Résumé : Background We undertook a trial to examine the feasibility of a self-guided mindfulness app, Smiling Mind, for children and adults with Autism Spectrum Disorder (ASD) and their parents. The trial encountered problems in recruitment, enrollment and retention which are described here. Methods : Of 169 eligible participants, only 22 consented and were randomly assigned to Smiling Mind (n = 12) or an attention control condition (n = 10). A further six participants withdrew during the study. Barriers to trial participation were subsequently explored through semi-structured interviews, to form case studies, and a follow-up survey. Results Interview and survey data highlighted parents? competing time commitments as a key barrier to participation. For children and adults with ASD, distraction and boredom were major challenges to engagement. Conclusions A number of modifiable variables in our recruitment procedures and intervention design ultimately resulted in a sample size that was too small to draw any firm conclusions from. Future ASD research can maximize sampling by broadening recruitment strategies and partnering with community services and schools. Engagement in mindfulness could also be improved by incorporating regular communication to motivate time poor participants. En ligne : https://doi.org/10.1016/j.rasd.2022.101991 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480

Characterizing difficulties with emotion regulation in toddlers with autism spectrum disorder / Taylor N. DAY in Research in Autism Spectrum Disorders, 96 (August 2022)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 96 (August 2022) . - 101992 Titre : Characterizing difficulties with emotion regulation in toddlers with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Taylor N. DAY, Auteur ; Carla A. MAZEFSKY, Auteur ; Amy M. WETHERBY, Auteur Article en page(s) : 101992 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  ASD  Toddlers  Early childhood  Emotion regulation  Emotional reactivity Index. décimale : PER Périodiques Résumé : Background Difficulties with emotion regulation (ER) underlie emotional/behavioral challenges and co-occurring psychiatric symptoms in autism spectrum disorder (ASD), yet very little is known about the early development of emotion dysregulation. The present study aimed to identify differences in positive and negative emotional reactivity and regulation strategies in toddlers with and without ASD. Method Nine tasks from the Laboratory Temperament Assessment Battery (Lab-TAB) were completed with 37 toddlers with and without ASD (22?28 months). Video-recordings of these tasks were coded by research assistants using a behavioral coding scheme tapping facial, bodily, and vocal affect and the frequency of ER strategies. Mixed model analyses were performed to examine the mean affect and total regulation strategies across each task and t-tests were conducted to assess the types of ER strategies utilized. Results Toddlers with ASD showed significantly less positive affect and greater frustration compared to non-ASD toddlers; reactivity was comparable between the groups for fear. Both groups used ER strategies in a similar pattern across tasks, with the exception that toddlers with ASD more often engaged in distraction to regulate. Effects of age and developmental level are discussed. Conclusions Toddlers with ASD were robustly characterized by greater frustration and lower joy despite frequent and age appropriate attempts to regulate their emotions. This study provides preliminary evidence that observable indicators of emotion dysregulation are present by two years of age. Clinical implications and future research directions are discussed. En ligne : https://doi.org/10.1016/j.rasd.2022.101992 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480 [article] Characterizing difficulties with emotion regulation in toddlers with autism spectrum disorder [Texte imprimé et/ou numérique] / Taylor N. DAY, Auteur ; Carla A. MAZEFSKY, Auteur ; Amy M. WETHERBY, Auteur . - 101992. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 96 (August 2022) . - 101992 Mots-clés : Autism spectrum disorder  ASD  Toddlers  Early childhood  Emotion regulation  Emotional reactivity Index. décimale : PER Périodiques Résumé : Background Difficulties with emotion regulation (ER) underlie emotional/behavioral challenges and co-occurring psychiatric symptoms in autism spectrum disorder (ASD), yet very little is known about the early development of emotion dysregulation. The present study aimed to identify differences in positive and negative emotional reactivity and regulation strategies in toddlers with and without ASD. Method Nine tasks from the Laboratory Temperament Assessment Battery (Lab-TAB) were completed with 37 toddlers with and without ASD (22?28 months). Video-recordings of these tasks were coded by research assistants using a behavioral coding scheme tapping facial, bodily, and vocal affect and the frequency of ER strategies. Mixed model analyses were performed to examine the mean affect and total regulation strategies across each task and t-tests were conducted to assess the types of ER strategies utilized. Results Toddlers with ASD showed significantly less positive affect and greater frustration compared to non-ASD toddlers; reactivity was comparable between the groups for fear. Both groups used ER strategies in a similar pattern across tasks, with the exception that toddlers with ASD more often engaged in distraction to regulate. Effects of age and developmental level are discussed. Conclusions Toddlers with ASD were robustly characterized by greater frustration and lower joy despite frequent and age appropriate attempts to regulate their emotions. This study provides preliminary evidence that observable indicators of emotion dysregulation are present by two years of age. Clinical implications and future research directions are discussed. En ligne : https://doi.org/10.1016/j.rasd.2022.101992 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480

Brain oscillatory patterns of affective prosody perception in children with autism spectrum disorder / Aleksandra V. MASLENNIKOVA in Research in Autism Spectrum Disorders, 96 (August 2022)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 96 (August 2022) . - 101993 Titre : Brain oscillatory patterns of affective prosody perception in children with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Aleksandra V. MASLENNIKOVA, Auteur ; Galina V. PORTNOVA, Auteur ; Olga V. MARTYNOVA, Auteur Article en page(s) : 101993 Langues : Anglais (eng) Mots-clés : ASD  Prosody  Emotions  EEG  Pitch  Loudness Index. décimale : PER Périodiques Résumé : Background Paralinguistic features, such as prosody (tempo, loudness, and timbre), are an essential marker of a speaker?s emotional state. Abnormal processing of emotional prosody may result in the deficient social behavior associated with autism spectrum disorder (ASD). Method Two groups of children participated in our study: the ASD group consisted of 30 preschoolers from 4 to 6 years of age and 24 typically developing (TD) peers. An electroencephalogram (EEG) was acquired in response to a combination of syllables uttered with the following types of emotional prosody: joy, anger, sadness, fear, and calmness. Results Children with ASD and TD showed a similar EEG oscillatory response to fear and anger prosodies. Significant group differences in power spectral density (PSD) were detected for sad and joy intonations. The PSD differences between pairs of intonations, such as joyful and sad, sad and neutral, or joyful and neutral, were significantly higher in the control group than in the ASD group. EEG responses to affective prosody also demonstrated less hemispheric asymmetry in the ASD than in the TD group. Conclusions Our results suggest that difficulties in emotional prosody recognition in autistic children could be based on the atypical processing of specific acoustic features coding differences between sad, neutral, and joyful intonations and could underlie emotional perception deficits in individuals with ASD. En ligne : https://doi.org/10.1016/j.rasd.2022.101993 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480 [article] Brain oscillatory patterns of affective prosody perception in children with autism spectrum disorder [Texte imprimé et/ou numérique] / Aleksandra V. MASLENNIKOVA, Auteur ; Galina V. PORTNOVA, Auteur ; Olga V. MARTYNOVA, Auteur . - 101993. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 96 (August 2022) . - 101993 Mots-clés : ASD  Prosody  Emotions  EEG  Pitch  Loudness Index. décimale : PER Périodiques Résumé : Background Paralinguistic features, such as prosody (tempo, loudness, and timbre), are an essential marker of a speaker?s emotional state. Abnormal processing of emotional prosody may result in the deficient social behavior associated with autism spectrum disorder (ASD). Method Two groups of children participated in our study: the ASD group consisted of 30 preschoolers from 4 to 6 years of age and 24 typically developing (TD) peers. An electroencephalogram (EEG) was acquired in response to a combination of syllables uttered with the following types of emotional prosody: joy, anger, sadness, fear, and calmness. Results Children with ASD and TD showed a similar EEG oscillatory response to fear and anger prosodies. Significant group differences in power spectral density (PSD) were detected for sad and joy intonations. The PSD differences between pairs of intonations, such as joyful and sad, sad and neutral, or joyful and neutral, were significantly higher in the control group than in the ASD group. EEG responses to affective prosody also demonstrated less hemispheric asymmetry in the ASD than in the TD group. Conclusions Our results suggest that difficulties in emotional prosody recognition in autistic children could be based on the atypical processing of specific acoustic features coding differences between sad, neutral, and joyful intonations and could underlie emotional perception deficits in individuals with ASD. En ligne : https://doi.org/10.1016/j.rasd.2022.101993 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480

A natural history study of medical cannabis consumption in pediatric autism in the United States / Mary Ann DILIBERTO in Research in Autism Spectrum Disorders, 96 (August 2022)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 96 (August 2022) . - 101994 Titre : A natural history study of medical cannabis consumption in pediatric autism in the United States Type de document : Texte imprimé et/ou numérique Auteurs : Mary Ann DILIBERTO, Auteur ; Athena F. ZUPPA, Auteur ; Amanda CORNETTA, Auteur ; Walter FAIG, Auteur ; Tryce SCULLY, Auteur ; Amanda BENNETT, Auteur ; Meghan THOMAS, Auteur ; Elizabeth WARD, Auteur ; Stephen BARR, Auteur ; Benjamin E. YERYS, Auteur Article en page(s) : 101994 Langues : Anglais (eng) Mots-clés : Marijuana  Treatment  Alternative medicine  Children  Youth Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder is specifically approved for medical cannabis consumption in 20 U.S. states, the District of Columbia, and the Territory of Puerto Rico. Despite increased access, there is limited knowledge about who consumes medical cannabis, what they consume, and perceived effectiveness. We addressed these gaps by conducting a natural history study of medical cannabis consumption. Method Children and their families engaged with a large pediatric care system were recruited to complete a telephonic study regarding their medical cannabis consumption. All children had to be consuming approved medical cannabis products issued from a state that had legalized medical cannabis for the treatment of ASD or related behaviors (irritability, hyperactivity, anxiety) (N = 89). Results The sample?s ?level of support? and gender-ratio reflected the general autism population (~33 % requiring ?Very Substantial Support? and ~80 % male). The most common treatment targets were ASD behaviors (repetitive behaviors) and irritability. More children consumed compounds with high cannabidiol (CBD) and low or no tetrahydrocannabinol (THC). While dose did not affect overall perceived effectiveness, compounds with high-levels of CBD and low-levels of THC (CBD-dominant) were perceived as more effective than CBD-only. Conclusions This ?real world? study revealed that medical cannabis is being used to treat a wide range of behaviors. Our study also suggests that children consume CBD-rich products, and the effectiveness of CBD-dosing may be tied to the inclusion of THC in the compound. Future research should evaluate optimal dosing with a particular focus on the CBD-to-THC ratio. En ligne : https://doi.org/10.1016/j.rasd.2022.101994 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480 [article] A natural history study of medical cannabis consumption in pediatric autism in the United States [Texte imprimé et/ou numérique] / Mary Ann DILIBERTO, Auteur ; Athena F. ZUPPA, Auteur ; Amanda CORNETTA, Auteur ; Walter FAIG, Auteur ; Tryce SCULLY, Auteur ; Amanda BENNETT, Auteur ; Meghan THOMAS, Auteur ; Elizabeth WARD, Auteur ; Stephen BARR, Auteur ; Benjamin E. YERYS, Auteur . - 101994. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 96 (August 2022) . - 101994 Mots-clés : Marijuana  Treatment  Alternative medicine  Children  Youth Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder is specifically approved for medical cannabis consumption in 20 U.S. states, the District of Columbia, and the Territory of Puerto Rico. Despite increased access, there is limited knowledge about who consumes medical cannabis, what they consume, and perceived effectiveness. We addressed these gaps by conducting a natural history study of medical cannabis consumption. Method Children and their families engaged with a large pediatric care system were recruited to complete a telephonic study regarding their medical cannabis consumption. All children had to be consuming approved medical cannabis products issued from a state that had legalized medical cannabis for the treatment of ASD or related behaviors (irritability, hyperactivity, anxiety) (N = 89). Results The sample?s ?level of support? and gender-ratio reflected the general autism population (~33 % requiring ?Very Substantial Support? and ~80 % male). The most common treatment targets were ASD behaviors (repetitive behaviors) and irritability. More children consumed compounds with high cannabidiol (CBD) and low or no tetrahydrocannabinol (THC). While dose did not affect overall perceived effectiveness, compounds with high-levels of CBD and low-levels of THC (CBD-dominant) were perceived as more effective than CBD-only. Conclusions This ?real world? study revealed that medical cannabis is being used to treat a wide range of behaviors. Our study also suggests that children consume CBD-rich products, and the effectiveness of CBD-dosing may be tied to the inclusion of THC in the compound. Future research should evaluate optimal dosing with a particular focus on the CBD-to-THC ratio. En ligne : https://doi.org/10.1016/j.rasd.2022.101994 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480

Online safety experiences of autistic young people: An Interpretative Phenomenological Analysis / Kirsty MACMILLAN in Research in Autism Spectrum Disorders, 96 (August 2022)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 96 (August 2022) . - 101995 Titre : Online safety experiences of autistic young people: An Interpretative Phenomenological Analysis Type de document : Texte imprimé et/ou numérique Auteurs : Kirsty MACMILLAN, Auteur ; Tessa BERG, Auteur ; Mike JUST, Auteur ; Mary E. STEWART, Auteur Article en page(s) : 101995 Langues : Anglais (eng) Mots-clés : Autism  Online safety  Qualitative research  IPA Index. décimale : PER Périodiques Résumé : Background Many autistic young people use online devices for social connection and to share interests. However, there is limited research regarding autistic online safety behaviours. Compared with non-autistic children, parental surveys have indicated that autistic young people are less likely to block people and/or online sites. To date, no research has explored autistic young people?s perceptions of their online safety experiences. This qualitative research explored autistic young people?s experiences of communicating with others online, as well as their online safety experiences. Method Semi-structured interviews were conducted with 14 autistic young people aged 11?17 years (M = 14.0, SD = 2.2), including 8 males (M = 13.9, SD = 2.1) and 6 females (M = 14.5, SD = 2.5). These were conducted face to face (n = 1), phone call (n = 2), or via Skype (n = 8) or live web chat (n = 3). Questions explored factors relating to autistic young people?s online safety experiences. Results Interpretative Phenomenological Analysis was used to analyse the data. In line with previous studies, autistic young people reported being victims of cyberbullying. Young autistic females reported being subject to online sexual harassment. While participants? online experiences varied, there were commonalities, including a desire for more support to block online comments and/or individuals. Conclusions Our results support previous findings that autistic young people are subject to online harassment and are not confident blocking unwanted contact from others online. Future interventions will be more readily accepted and ecologically valid if they address the unique needs of autistic young people. En ligne : https://doi.org/10.1016/j.rasd.2022.101995 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480 [article] Online safety experiences of autistic young people: An Interpretative Phenomenological Analysis [Texte imprimé et/ou numérique] / Kirsty MACMILLAN, Auteur ; Tessa BERG, Auteur ; Mike JUST, Auteur ; Mary E. STEWART, Auteur . - 101995. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 96 (August 2022) . - 101995 Mots-clés : Autism  Online safety  Qualitative research  IPA Index. décimale : PER Périodiques Résumé : Background Many autistic young people use online devices for social connection and to share interests. However, there is limited research regarding autistic online safety behaviours. Compared with non-autistic children, parental surveys have indicated that autistic young people are less likely to block people and/or online sites. To date, no research has explored autistic young people?s perceptions of their online safety experiences. This qualitative research explored autistic young people?s experiences of communicating with others online, as well as their online safety experiences. Method Semi-structured interviews were conducted with 14 autistic young people aged 11?17 years (M = 14.0, SD = 2.2), including 8 males (M = 13.9, SD = 2.1) and 6 females (M = 14.5, SD = 2.5). These were conducted face to face (n = 1), phone call (n = 2), or via Skype (n = 8) or live web chat (n = 3). Questions explored factors relating to autistic young people?s online safety experiences. Results Interpretative Phenomenological Analysis was used to analyse the data. In line with previous studies, autistic young people reported being victims of cyberbullying. Young autistic females reported being subject to online sexual harassment. While participants? online experiences varied, there were commonalities, including a desire for more support to block online comments and/or individuals. Conclusions Our results support previous findings that autistic young people are subject to online harassment and are not confident blocking unwanted contact from others online. Future interventions will be more readily accepted and ecologically valid if they address the unique needs of autistic young people. En ligne : https://doi.org/10.1016/j.rasd.2022.101995 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480

Exploring leisure time use and impact on well-being among transition-age autistic youth / Sara C. FOLTA in Research in Autism Spectrum Disorders, 96 (August 2022)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 96 (August 2022) . - 101996 Titre : Exploring leisure time use and impact on well-being among transition-age autistic youth Type de document : Texte imprimé et/ou numérique Auteurs : Sara C. FOLTA, Auteur ; Linda G. BANDINI, Auteur ; Aviva MUST, Auteur ; Jessica PELLETIER, Auteur ; Kate RYAN, Auteur ; Carol CURTIN, Auteur Article en page(s) : 101996 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Leisure time  Quality of life  Transition-age youth Index. décimale : PER Périodiques Résumé : Background Quality of life (QOL) is lower for transition-age autistic youth compared to typically developing counterparts. Leisure-time pursuits have been linked to higher quality of life in the general population and among autistic adults. The purpose of this qualitative study was to explore leisure-time use among transition-age autistic youth. Method Youth ages 18?23 years were recruited through universities and organizations that serve the autistic population and their families across the United States. Participants took photos of their leisure-time activities over a 7-day period using their own smartphones. They were then interviewed via Zoom using a semi-structured interview guide that was based on the Self-Determination Theory framework and the Iwasaki leisure-time model. Data were analyzed using directed qualitative content analysis based on the theoretical framework. Results Eighteen young autistic adults participated in the study (nine male, five female, three agender/non-binary, and one transgender). Solitary, screen-based activities were most common. Major themes were that activities contributed positively to a sense of achievement and a sense of autonomy, and there were few major barriers to favored activities. While most activities were done alone, rather than describing these activities as isolating, activities helped participants cope with stress. Participants gained a sense of connection when they were engaged in leisure activities with others who shared common interests. Conclusions Results suggest that appropriate interventions may support youth in choosing activities they most enjoy, even if they appear to be solitary or sedentary, and to help ensure that youth are gaining maximal benefits from these activities. En ligne : https://doi.org/10.1016/j.rasd.2022.101996 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480 [article] Exploring leisure time use and impact on well-being among transition-age autistic youth [Texte imprimé et/ou numérique] / Sara C. FOLTA, Auteur ; Linda G. BANDINI, Auteur ; Aviva MUST, Auteur ; Jessica PELLETIER, Auteur ; Kate RYAN, Auteur ; Carol CURTIN, Auteur . - 101996. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 96 (August 2022) . - 101996 Mots-clés : Autism spectrum disorder  Leisure time  Quality of life  Transition-age youth Index. décimale : PER Périodiques Résumé : Background Quality of life (QOL) is lower for transition-age autistic youth compared to typically developing counterparts. Leisure-time pursuits have been linked to higher quality of life in the general population and among autistic adults. The purpose of this qualitative study was to explore leisure-time use among transition-age autistic youth. Method Youth ages 18?23 years were recruited through universities and organizations that serve the autistic population and their families across the United States. Participants took photos of their leisure-time activities over a 7-day period using their own smartphones. They were then interviewed via Zoom using a semi-structured interview guide that was based on the Self-Determination Theory framework and the Iwasaki leisure-time model. Data were analyzed using directed qualitative content analysis based on the theoretical framework. Results Eighteen young autistic adults participated in the study (nine male, five female, three agender/non-binary, and one transgender). Solitary, screen-based activities were most common. Major themes were that activities contributed positively to a sense of achievement and a sense of autonomy, and there were few major barriers to favored activities. While most activities were done alone, rather than describing these activities as isolating, activities helped participants cope with stress. Participants gained a sense of connection when they were engaged in leisure activities with others who shared common interests. Conclusions Results suggest that appropriate interventions may support youth in choosing activities they most enjoy, even if they appear to be solitary or sedentary, and to help ensure that youth are gaining maximal benefits from these activities. En ligne : https://doi.org/10.1016/j.rasd.2022.101996 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480

Judging intentionality in the context of ambiguous actions among autistic adults / Antonia EISENKOECK in Research in Autism Spectrum Disorders, 96 (August 2022)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 96 (August 2022) . - 101997 Titre : Judging intentionality in the context of ambiguous actions among autistic adults Type de document : Texte imprimé et/ou numérique Auteurs : Antonia EISENKOECK, Auteur ; Rachel J. M. SLAVNY-CROSS, Auteur ; James W. MOORE, Auteur Article en page(s) : 101997 Langues : Anglais (eng) Mots-clés : Social cognition  Theory of mind  Intention attribution  Intentionality bias Index. décimale : PER Périodiques Résumé : Background Discerning intentional from unintentional actions is a key aspect of social cognition. Mental state attribution tasks show that autistic people are less accurate than neurotypicals in attributing an agent?s intention when there is clearly a right answer. Little is known about how autistic people judge the intentionality of ambiguous actions (i.e., actions that are neither clearly intentional nor clearly unintentional). Aims This study sought to find out whether autistic individuals differ in their interpretation of ambiguous action compared to neurotypical controls. Methods and procedures 20 autistic and 20 neurotypical adults completed an ambiguous action and theory of mind task. Autistic traits, verbal reasoning and non-verbal perceptual reasoning ability were measured. Outcomes and results Results show that intentionality endorsement scores for ambiguous but prototypically accidental actions were higher in autistic participants than controls. Theory of Mind (ToM) scores did not correlate with intentionality endorsement scores in either group therefore group differences could not be explained by ToM ability. Conclusion and implications Autistic participants had a tendency to over-attribute intention compared to neurotypicals, which could not be explained by ToM ability. Studying ambiguous action is important with respect to ecological validity, given that we often face ambiguous actions during social encounters. En ligne : https://doi.org/10.1016/j.rasd.2022.101997 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480 [article] Judging intentionality in the context of ambiguous actions among autistic adults [Texte imprimé et/ou numérique] / Antonia EISENKOECK, Auteur ; Rachel J. M. SLAVNY-CROSS, Auteur ; James W. MOORE, Auteur . - 101997. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 96 (August 2022) . - 101997 Mots-clés : Social cognition  Theory of mind  Intention attribution  Intentionality bias Index. décimale : PER Périodiques Résumé : Background Discerning intentional from unintentional actions is a key aspect of social cognition. Mental state attribution tasks show that autistic people are less accurate than neurotypicals in attributing an agent?s intention when there is clearly a right answer. Little is known about how autistic people judge the intentionality of ambiguous actions (i.e., actions that are neither clearly intentional nor clearly unintentional). Aims This study sought to find out whether autistic individuals differ in their interpretation of ambiguous action compared to neurotypical controls. Methods and procedures 20 autistic and 20 neurotypical adults completed an ambiguous action and theory of mind task. Autistic traits, verbal reasoning and non-verbal perceptual reasoning ability were measured. Outcomes and results Results show that intentionality endorsement scores for ambiguous but prototypically accidental actions were higher in autistic participants than controls. Theory of Mind (ToM) scores did not correlate with intentionality endorsement scores in either group therefore group differences could not be explained by ToM ability. Conclusion and implications Autistic participants had a tendency to over-attribute intention compared to neurotypicals, which could not be explained by ToM ability. Studying ambiguous action is important with respect to ecological validity, given that we often face ambiguous actions during social encounters. En ligne : https://doi.org/10.1016/j.rasd.2022.101997 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480

Motor skills, visual perception, and visual-motor integration in children and youth with Autism Spectrum Disorder / Leila FABER in Research in Autism Spectrum Disorders, 96 (August 2022)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 96 (August 2022) . - 101998 Titre : Motor skills, visual perception, and visual-motor integration in children and youth with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Leila FABER, Auteur ; Nellie VAN DEN BOS, Auteur ; Suzanne HOUWEN, Auteur ; Marina M. SCHOEMAKER, Auteur ; Sara ROSENBLUM, Auteur Article en page(s) : 101998 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder  Motor skills  Visual perception  Visual-motor integration Index. décimale : PER Périodiques Résumé : Background Motor skill deficits are prevalent among children with Autism Spectrum Disorder (ASD) however, little is known about the underlying mechanism of these deficits. In response to this gap, this study investigated how visual perception (VP) and visual-motor integration (VMI) are associated with motor skills among children and youth with ASD. Methods Sixty-seven individuals with ASD and sixty-seven age- and gender-matched individuals without ASD (age range: 9.83?15.13 years) participated. Motor skills were assessed with the Movement Assessment Battery for Children-2 (MABC-2) and VP and VMI with the respective components of the Beery-Buktenica Developmental Test of Visual-Motor Integration-6 (Beery VMI-6). Results Significantly more children and youth with ASD were in the red and orange zone of the MABC-2 traffic-lighting system for the total MABC-2 and the Aiming and Catching and Balance components compared to the children and youth without ASD. Both groups did not differ on the VP and VMI components of the Beery VMI-6. Pearson correlations between VP and VMI, and motor skills were weak but significant for the individuals without ASD, but not for the ASD group. Conclusion The current study added to the evidence about motor skill deficits among children and youth with ASD. VP and VMI were not related to motor skills, suggesting that these functions ? as measured in the current study ? are no underlying mechanisms of motor skill deficits of children with ASD and average intelligence. Diagnostic implications are provided for the evidence of motor skill deficits among children and youth with ASD. En ligne : https://doi.org/10.1016/j.rasd.2022.101998 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480 [article] Motor skills, visual perception, and visual-motor integration in children and youth with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Leila FABER, Auteur ; Nellie VAN DEN BOS, Auteur ; Suzanne HOUWEN, Auteur ; Marina M. SCHOEMAKER, Auteur ; Sara ROSENBLUM, Auteur . - 101998. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 96 (August 2022) . - 101998 Mots-clés : Autism Spectrum Disorder  Motor skills  Visual perception  Visual-motor integration Index. décimale : PER Périodiques Résumé : Background Motor skill deficits are prevalent among children with Autism Spectrum Disorder (ASD) however, little is known about the underlying mechanism of these deficits. In response to this gap, this study investigated how visual perception (VP) and visual-motor integration (VMI) are associated with motor skills among children and youth with ASD. Methods Sixty-seven individuals with ASD and sixty-seven age- and gender-matched individuals without ASD (age range: 9.83?15.13 years) participated. Motor skills were assessed with the Movement Assessment Battery for Children-2 (MABC-2) and VP and VMI with the respective components of the Beery-Buktenica Developmental Test of Visual-Motor Integration-6 (Beery VMI-6). Results Significantly more children and youth with ASD were in the red and orange zone of the MABC-2 traffic-lighting system for the total MABC-2 and the Aiming and Catching and Balance components compared to the children and youth without ASD. Both groups did not differ on the VP and VMI components of the Beery VMI-6. Pearson correlations between VP and VMI, and motor skills were weak but significant for the individuals without ASD, but not for the ASD group. Conclusion The current study added to the evidence about motor skill deficits among children and youth with ASD. VP and VMI were not related to motor skills, suggesting that these functions ? as measured in the current study ? are no underlying mechanisms of motor skill deficits of children with ASD and average intelligence. Diagnostic implications are provided for the evidence of motor skill deficits among children and youth with ASD. En ligne : https://doi.org/10.1016/j.rasd.2022.101998 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480

?They?re either afraid or ignorant?: Experiences of stigma and blame among fathers raising autistic children / Asalah ALAREEKI in Research in Autism Spectrum Disorders, 96 (August 2022)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 96 (August 2022) . - 101999 Titre : ?They?re either afraid or ignorant?: Experiences of stigma and blame among fathers raising autistic children Type de document : Texte imprimé et/ou numérique Auteurs : Asalah ALAREEKI, Auteur ; Leah SHIPTON, Auteur ; Bonnie LASHEWICZ, Auteur Article en page(s) : 101999 Langues : Anglais (eng) Mots-clés : Autism  Blame  Courtesy stigma  Disability  Fathers  Parenting Index. décimale : PER Périodiques Résumé : Background Fathers of autistic children experience courtesy stigma, or ?stigma by association?, in ways that are distinct from experiences of mothers, yet most autism-related research is focused on white, middle-class mothers. We investigated courtesy stigma experienced by a small but diverse sample of fathers of autistic children. Method Using a narrative approach, we looked for evidence of courtesy stigma in stories collected through 13 interviews with 11 fathers about raising autistic children (aged 2-14 years). Results The themes we generated pertained to, and went beyond, courtesy stigma experiences and included: 1- stigma toward the autistic child, 2- fathers feeling blamed, 3 ? experiences of courtesy stigma including ethnic subgroup navigation of stigma and blame. Our final theme is: 4- fathers resisting stigma and blame through personal growth and openness. Deficit-oriented stereotypes of autistic people are embedded in societal structures and stigma and blame seep into fathers? daily movements through professional, educational and public spaces as well as personal and ethnic subgroup networks. Fathers shared evidence of their vulnerability as parents and offered a glimpse of the push and/or pull they can encounter within their ethnic subgroup community. Conclusions Ongoing research on fathers? experience is needed and we offer suggestions for capturing perspectives of fathers from specific racial, ethnic and cultural backgrounds. We recommend that practitioners be sensitized to complex workings of stigma and blame that may leave fathers of autistic children inclined to avoid or delay diagnosis for fear of stigma. En ligne : https://doi.org/10.1016/j.rasd.2022.101999 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480 [article] ?They?re either afraid or ignorant?: Experiences of stigma and blame among fathers raising autistic children [Texte imprimé et/ou numérique] / Asalah ALAREEKI, Auteur ; Leah SHIPTON, Auteur ; Bonnie LASHEWICZ, Auteur . - 101999. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 96 (August 2022) . - 101999 Mots-clés : Autism  Blame  Courtesy stigma  Disability  Fathers  Parenting Index. décimale : PER Périodiques Résumé : Background Fathers of autistic children experience courtesy stigma, or ?stigma by association?, in ways that are distinct from experiences of mothers, yet most autism-related research is focused on white, middle-class mothers. We investigated courtesy stigma experienced by a small but diverse sample of fathers of autistic children. Method Using a narrative approach, we looked for evidence of courtesy stigma in stories collected through 13 interviews with 11 fathers about raising autistic children (aged 2-14 years). Results The themes we generated pertained to, and went beyond, courtesy stigma experiences and included: 1- stigma toward the autistic child, 2- fathers feeling blamed, 3 ? experiences of courtesy stigma including ethnic subgroup navigation of stigma and blame. Our final theme is: 4- fathers resisting stigma and blame through personal growth and openness. Deficit-oriented stereotypes of autistic people are embedded in societal structures and stigma and blame seep into fathers? daily movements through professional, educational and public spaces as well as personal and ethnic subgroup networks. Fathers shared evidence of their vulnerability as parents and offered a glimpse of the push and/or pull they can encounter within their ethnic subgroup community. Conclusions Ongoing research on fathers? experience is needed and we offer suggestions for capturing perspectives of fathers from specific racial, ethnic and cultural backgrounds. We recommend that practitioners be sensitized to complex workings of stigma and blame that may leave fathers of autistic children inclined to avoid or delay diagnosis for fear of stigma. En ligne : https://doi.org/10.1016/j.rasd.2022.101999 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480

Chaotic family environments and depressive symptoms in parents of autistic children: The protective role of optimism / Deborah RAFFERTY in Research in Autism Spectrum Disorders, 96 (August 2022)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 96 (August 2022) . - 102000 Titre : Chaotic family environments and depressive symptoms in parents of autistic children: The protective role of optimism Type de document : Texte imprimé et/ou numérique Auteurs : Deborah RAFFERTY, Auteur ; Mackenzie PRESTON, Auteur ; Whitney SULLIVAN, Auteur ; Naomi EKAS, Auteur Article en page(s) : 102000 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Optimism  Family functioning  Depression  Fathers Index. décimale : PER Périodiques Résumé : Background Raising an autistic child is associated with increased parenting stress and higher rates of depression for both mothers and fathers. While most research has focused on the challenges related to having an autistic child, such as higher rates of chaotic family environments, an emerging body of research has begun to examine the protective effects of optimism to reduce the negative impact on parent mental health. Method A total of 133 mothers and 78 fathers of autistic children between the ages of 2?10 years participated in the study. Parents answered questionnaires related to their family functioning, dispositional optimism, and depressive symptoms. Results Results found a significant family chaotic environment X optimism X parent gender interaction. For mothers and fathers, higher levels of chaotic family environment were associated with increased depressive symptoms whereas increased levels of optimism were associated with lower levels of depressive symptoms. However, optimism was only protective for mothers and not for fathers. Conclusions The results highlight the need for the inclusion of optimism in parent-focused interventions. En ligne : https://doi.org/10.1016/j.rasd.2022.102000 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480 [article] Chaotic family environments and depressive symptoms in parents of autistic children: The protective role of optimism [Texte imprimé et/ou numérique] / Deborah RAFFERTY, Auteur ; Mackenzie PRESTON, Auteur ; Whitney SULLIVAN, Auteur ; Naomi EKAS, Auteur . - 102000. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 96 (August 2022) . - 102000 Mots-clés : Autism spectrum disorder  Optimism  Family functioning  Depression  Fathers Index. décimale : PER Périodiques Résumé : Background Raising an autistic child is associated with increased parenting stress and higher rates of depression for both mothers and fathers. While most research has focused on the challenges related to having an autistic child, such as higher rates of chaotic family environments, an emerging body of research has begun to examine the protective effects of optimism to reduce the negative impact on parent mental health. Method A total of 133 mothers and 78 fathers of autistic children between the ages of 2?10 years participated in the study. Parents answered questionnaires related to their family functioning, dispositional optimism, and depressive symptoms. Results Results found a significant family chaotic environment X optimism X parent gender interaction. For mothers and fathers, higher levels of chaotic family environment were associated with increased depressive symptoms whereas increased levels of optimism were associated with lower levels of depressive symptoms. However, optimism was only protective for mothers and not for fathers. Conclusions The results highlight the need for the inclusion of optimism in parent-focused interventions. En ligne : https://doi.org/10.1016/j.rasd.2022.102000 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480

Examination of racial/ethnic disproportionality of autism in California / Paul LUELMO in Research in Autism Spectrum Disorders, 96 (August 2022)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 96 (August 2022) . - 102001 Titre : Examination of racial/ethnic disproportionality of autism in California Type de document : Texte imprimé et/ou numérique Auteurs : Paul LUELMO, Auteur ; Laura J. HALL, Auteur ; Ryan ESTRELLADO, Auteur Article en page(s) : 102001 Langues : Anglais (eng) Mots-clés : Autism  Racial/ethnic disproportionality  Inequities  Disparities  Special education Index. décimale : PER Périodiques Résumé : Background Racial/Ethnic disparities continue to exist for minoritized communities. This study is an examination of the risk ratio analysis of racial/ethnic special education disproportionality in schools for the category of autism in the state of California. Method We extracted and analyzed state level risk ratio data. We used descriptive statistics and compared school districts with significant disproportionality in autism across multiple variables (demographics, enrollment, English Learners, socio-economic status). Additionally, a caregiver survey was sent to caregivers in one disproportionate school district as part of a root cause analysis. Results It was found that, in 2019, all districts in California with a racial/ethnic significant disproportionality in the autism category were for the overidentification of White students. Importantly, all the districts in the sample had strikingly similar student demographics; a large majority of Latinx/Hispanic students, a large percentage of English Language Learners and low-income students. Results revealed a significant discrepancy between caregiver identified early signs of delays, or red flags of disability by Spanish-speaking Latinx caregivers (14%) and English-speaking caregivers (77%). Conclusions Researchers and school districts aiming to address systemic disparities in special education need to capture caregiver perspectives in their root cause analyses. Importantly, these findings point to the duty of school systems to address the autism identification and service gaps for families whose primary language is other than English. En ligne : https://doi.org/10.1016/j.rasd.2022.102001 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480 [article] Examination of racial/ethnic disproportionality of autism in California [Texte imprimé et/ou numérique] / Paul LUELMO, Auteur ; Laura J. HALL, Auteur ; Ryan ESTRELLADO, Auteur . - 102001. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 96 (August 2022) . - 102001 Mots-clés : Autism  Racial/ethnic disproportionality  Inequities  Disparities  Special education Index. décimale : PER Périodiques Résumé : Background Racial/Ethnic disparities continue to exist for minoritized communities. This study is an examination of the risk ratio analysis of racial/ethnic special education disproportionality in schools for the category of autism in the state of California. Method We extracted and analyzed state level risk ratio data. We used descriptive statistics and compared school districts with significant disproportionality in autism across multiple variables (demographics, enrollment, English Learners, socio-economic status). Additionally, a caregiver survey was sent to caregivers in one disproportionate school district as part of a root cause analysis. Results It was found that, in 2019, all districts in California with a racial/ethnic significant disproportionality in the autism category were for the overidentification of White students. Importantly, all the districts in the sample had strikingly similar student demographics; a large majority of Latinx/Hispanic students, a large percentage of English Language Learners and low-income students. Results revealed a significant discrepancy between caregiver identified early signs of delays, or red flags of disability by Spanish-speaking Latinx caregivers (14%) and English-speaking caregivers (77%). Conclusions Researchers and school districts aiming to address systemic disparities in special education need to capture caregiver perspectives in their root cause analyses. Importantly, these findings point to the duty of school systems to address the autism identification and service gaps for families whose primary language is other than English. En ligne : https://doi.org/10.1016/j.rasd.2022.102001 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480

Risperidone plasma concentrations are associated with hyperprolactinemia in autism spectrum disorder children: The impact of CYP2D6 polymorphisms / Monpat CHAMNANPHON in Research in Autism Spectrum Disorders, 96 (August 2022)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 96 (August 2022) . - 102002 Titre : Risperidone plasma concentrations are associated with hyperprolactinemia in autism spectrum disorder children: The impact of CYP2D6 polymorphisms Type de document : Texte imprimé et/ou numérique Auteurs : Monpat CHAMNANPHON, Auteur ; Natchaya VANWONG, Auteur ; Santirhat PROMMAS, Auteur ; Napatrupron KOOMDEE, Auteur ; Rattanaporn SUKPRASONG, Auteur ; Jiratha RACHANAKUL, Auteur ; Nutthan NUNTHARADTHANAPHONG, Auteur ; Yaowaluck HONGKAEW, Auteur ; Shobana JOHN, Auteur ; Nattawat NGAMSAMUT, Auteur ; Nopphadol NUNTAMOOL, Auteur ; Penkhae LIMSILA, Auteur ; Chonlaphat SUKASEM, Auteur Article en page(s) : 102002 Langues : Anglais (eng) Mots-clés : genotyping  Prolactin  ASD  Risperidone  Allele-specific primer extension  Luminex xTAG  Chemiluminescence immunoassay Index. décimale : PER Périodiques Résumé : Background Risperidone causes hyperprolactinemia by blocking D2 receptors on lactotrophs anterior pituitary, which prevents prolactin secretion inhibition. Risperidone is converted to 9-hydroxyrisperidone by the CYP2D6 enzyme. Polymorphisms in CYP2D6 may affect serum prolactin and could be a predictor of hyperprolactinemia. The goal of this study was to see if there was an association between CYP2D6 variants, risperidone dose, clinical data and serum prolactin levels in Thai children and adolescents with autism spectrum disorder (ASD). Method In 107 Thai ASD patients on risperidone, allele-specific primer extension and multiplex PCR platforms were used to genotype the CYP2D6 gene. The chemiluminescence immunoassay (CLIA) technique was used to measure fasting serum prolactin levels. Results The median serum prolactin level was 16.25?ng/mL (IQR; 10.43-22.18), and patients with CYP2D6*1/*5 (6.54%) had substantially lower prolactin levels than those with CYP2D6*1/*1 [median; 11.2?ng/mL (IQR; 3.95-21.10) vs. 21.3 (IQR; 14.43-32.18), p=0.032]. CYP2D6*1/*10, *10/*10, and *10/*41 produced less prolactin than *1/*1 (wild type). Furthermore, gender and risperidone dose were associated with significantly different prolactin levels with p-value 0.02 and 0.006, respectively. Multivariate analysis showed a significant association of serum prolactin level with body mass index and risperidone dose (p<0.05). Conclusions Our study showed that CYP2D6 carriers of absent and decreased functional alleles had lower serum prolactin levels in Thai ASD patients treated with risperidone treatment; this is important to clinicians, indicating that they should consider about CYP2D6 genotyping before beginning risperidone in ASD patients. CYP2D6 genotypes might be a predictor for levels of prolactin in clinical treatment. En ligne : https://doi.org/10.1016/j.rasd.2022.102002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480 [article] Risperidone plasma concentrations are associated with hyperprolactinemia in autism spectrum disorder children: The impact of CYP2D6 polymorphisms [Texte imprimé et/ou numérique] / Monpat CHAMNANPHON, Auteur ; Natchaya VANWONG, Auteur ; Santirhat PROMMAS, Auteur ; Napatrupron KOOMDEE, Auteur ; Rattanaporn SUKPRASONG, Auteur ; Jiratha RACHANAKUL, Auteur ; Nutthan NUNTHARADTHANAPHONG, Auteur ; Yaowaluck HONGKAEW, Auteur ; Shobana JOHN, Auteur ; Nattawat NGAMSAMUT, Auteur ; Nopphadol NUNTAMOOL, Auteur ; Penkhae LIMSILA, Auteur ; Chonlaphat SUKASEM, Auteur . - 102002. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 96 (August 2022) . - 102002 Mots-clés : genotyping  Prolactin  ASD  Risperidone  Allele-specific primer extension  Luminex xTAG  Chemiluminescence immunoassay Index. décimale : PER Périodiques Résumé : Background Risperidone causes hyperprolactinemia by blocking D2 receptors on lactotrophs anterior pituitary, which prevents prolactin secretion inhibition. Risperidone is converted to 9-hydroxyrisperidone by the CYP2D6 enzyme. Polymorphisms in CYP2D6 may affect serum prolactin and could be a predictor of hyperprolactinemia. The goal of this study was to see if there was an association between CYP2D6 variants, risperidone dose, clinical data and serum prolactin levels in Thai children and adolescents with autism spectrum disorder (ASD). Method In 107 Thai ASD patients on risperidone, allele-specific primer extension and multiplex PCR platforms were used to genotype the CYP2D6 gene. The chemiluminescence immunoassay (CLIA) technique was used to measure fasting serum prolactin levels. Results The median serum prolactin level was 16.25?ng/mL (IQR; 10.43-22.18), and patients with CYP2D6*1/*5 (6.54%) had substantially lower prolactin levels than those with CYP2D6*1/*1 [median; 11.2?ng/mL (IQR; 3.95-21.10) vs. 21.3 (IQR; 14.43-32.18), p=0.032]. CYP2D6*1/*10, *10/*10, and *10/*41 produced less prolactin than *1/*1 (wild type). Furthermore, gender and risperidone dose were associated with significantly different prolactin levels with p-value 0.02 and 0.006, respectively. Multivariate analysis showed a significant association of serum prolactin level with body mass index and risperidone dose (p<0.05). Conclusions Our study showed that CYP2D6 carriers of absent and decreased functional alleles had lower serum prolactin levels in Thai ASD patients treated with risperidone treatment; this is important to clinicians, indicating that they should consider about CYP2D6 genotyping before beginning risperidone in ASD patients. CYP2D6 genotypes might be a predictor for levels of prolactin in clinical treatment. En ligne : https://doi.org/10.1016/j.rasd.2022.102002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480

Dynamic Interactive Social Cognition Training in Virtual Reality (DiSCoVR) for adults with Autism Spectrum Disorder: A feasibility study / B. J. VAN PELT in Research in Autism Spectrum Disorders, 96 (August 2022)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 96 (August 2022) . - 102003 Titre : Dynamic Interactive Social Cognition Training in Virtual Reality (DiSCoVR) for adults with Autism Spectrum Disorder: A feasibility study Type de document : Texte imprimé et/ou numérique Auteurs : B. J. VAN PELT, Auteur ; S. A. NIJMAN, Auteur ; N. E. M. VAN HAREN, Auteur ; W. VELING, Auteur ; G. H. M. PIJNENBORG, Auteur ; I. D. C. VAN BALKOM, Auteur ; A. M. LANDLUST, Auteur ; K. GREAVES-LORD, Auteur Article en page(s) : 102003 Langues : Anglais (eng) Mots-clés : Social cognition training  Virtual reality  Autism spectrum disorder  Emotion perception  Theory of mind  Social functioning Index. décimale : PER Périodiques Résumé : Background Social cognitive difficulties in Autism Spectrum Disorder (ASD) can affect the daily lives of people with ASD profoundly, impacting the development and maintenance of meaningful social relations. Social cognition training (SCT) is commonly used for improving social functioning, but lacks ecological validity and the ability to effectively mimic social situations. Development of virtual reality (VR) interventions, focusing on enhancing social cognition, could add to the effectiveness of SCT within ASD care, by offering a safe, interactive and practical training setting, where generalization of knowledge and skills to the real-world are promoted. In this paper, our primary aim is to evaluate the feasibility and acceptance by participants and therapists of the Dynamic Interactive Social Cognition Method Training in Virtual Reality (DiSCoVR) protocol as developed for adults with schizophrenic spectrum disorder (SSD), adapted for ASD (DiSCoVR-A). 26 participants, aged 18?63, took part in a pilot study. 22 participants completed baseline and post-assessment, including primary outcome evaluation assessment through a semi-structured interview. Secondary measures focused on social cognition, emotion recognition, mental flexibility, social anxiety, empathy and social responsiveness and were assessed at baseline (T0), post-treatment (T1), and at follow-up (T2) sixteen weeks after completion of the intervention. Results Our results show that the majority of participant and therapists found the VR intervention acceptable and feasible, as reported in evaluation questionnaires and interviews. Conclusion These preliminary findings are promising; however, controlled research is needed to further investigate the effectiveness of VR within social cognition training for adults with ASD. En ligne : https://doi.org/10.1016/j.rasd.2022.102003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480 [article] Dynamic Interactive Social Cognition Training in Virtual Reality (DiSCoVR) for adults with Autism Spectrum Disorder: A feasibility study [Texte imprimé et/ou numérique] / B. J. VAN PELT, Auteur ; S. A. NIJMAN, Auteur ; N. E. M. VAN HAREN, Auteur ; W. VELING, Auteur ; G. H. M. PIJNENBORG, Auteur ; I. D. C. VAN BALKOM, Auteur ; A. M. LANDLUST, Auteur ; K. GREAVES-LORD, Auteur . - 102003. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 96 (August 2022) . - 102003 Mots-clés : Social cognition training  Virtual reality  Autism spectrum disorder  Emotion perception  Theory of mind  Social functioning Index. décimale : PER Périodiques Résumé : Background Social cognitive difficulties in Autism Spectrum Disorder (ASD) can affect the daily lives of people with ASD profoundly, impacting the development and maintenance of meaningful social relations. Social cognition training (SCT) is commonly used for improving social functioning, but lacks ecological validity and the ability to effectively mimic social situations. Development of virtual reality (VR) interventions, focusing on enhancing social cognition, could add to the effectiveness of SCT within ASD care, by offering a safe, interactive and practical training setting, where generalization of knowledge and skills to the real-world are promoted. In this paper, our primary aim is to evaluate the feasibility and acceptance by participants and therapists of the Dynamic Interactive Social Cognition Method Training in Virtual Reality (DiSCoVR) protocol as developed for adults with schizophrenic spectrum disorder (SSD), adapted for ASD (DiSCoVR-A). 26 participants, aged 18?63, took part in a pilot study. 22 participants completed baseline and post-assessment, including primary outcome evaluation assessment through a semi-structured interview. Secondary measures focused on social cognition, emotion recognition, mental flexibility, social anxiety, empathy and social responsiveness and were assessed at baseline (T0), post-treatment (T1), and at follow-up (T2) sixteen weeks after completion of the intervention. Results Our results show that the majority of participant and therapists found the VR intervention acceptable and feasible, as reported in evaluation questionnaires and interviews. Conclusion These preliminary findings are promising; however, controlled research is needed to further investigate the effectiveness of VR within social cognition training for adults with ASD. En ligne : https://doi.org/10.1016/j.rasd.2022.102003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=480