Autistic traits in childhood and post-traumatic stress disorder as young adults: a cohort study / Alice M. G. QUINTON in Journal of Child Psychology and Psychiatry, 66-10 (October 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1514-1525 Titre : Autistic traits in childhood and post-traumatic stress disorder as young adults: a cohort study Type de document : texte imprimé Auteurs : Alice M. G. QUINTON, Auteur ; Freya RUMBALL, Auteur ; Angelica RONALD, Auteur ; Helen L. FISHER, Auteur ; Louise ARSENEAULT, Auteur ; Francesca HAPPE, Auteur ; Andrea DANESE, Auteur Article en page(s) : p.1514-1525 Langues : Anglais (eng) Mots-clés : Autism  autism spectrum  trauma  PTSD  psychopathology Index. décimale : PER Périodiques Résumé : Background Despite the higher prevalence of childhood traumatic experiences and post-traumatic stress disorder (PTSD) in autistic adults, research on trauma-related psychopathology and autistic traits in young people is lacking. This study examined if high autistic traits in childhood predispose individuals to traumatic experiences, the development of PTSD and general psychopathology, and greater functional impairment by age 18, in both the general population and a subsample of trauma-exposed young people. Methods Data were utilised from the Environmental Risk (E-Risk) Longitudinal Twin Study, a nationally representative cohort of 2,232 same-sex twins born in 1994 1995 across England and Wales. Participants were a subset of children whose parents completed the Childhood Autism Spectrum Test (CAST), during assessments at ages 8, 9 and/or 12 years (N 1,504). We tested associations between autistic traits in childhood and age-18 reports of lifetime trauma exposure, lifetime PTSD diagnosis, general psychopathology (?p-factor?) and NEET status (?not in employment, education or training?). Analyses were conducted controlling for sex, family socioeconomic status (SES), intelligence quotient (IQ) and accounting for family clustering. Results Higher autistic traits in childhood were significantly associated with greater reports of lifetime trauma exposure (Odd Ratio [OR] 1.26, 95% Confidence Intervals [CI] 1.03; 1.54), lifetime PTSD diagnosis (OR 1.91, 95% CI 1.29; 2.82), general psychopathology (beta 3.22, 95% CI 1.84; 4.60) and NEET status (OR 1.48, 95% CI 1.05; 2.09) at age 18. Only the associations of autistic traits with PTSD and general psychopathology were robust to adjustment for potential confounders. Among trauma-exposed children, autistic traits were also significantly associated with lifetime PTSD diagnosis (OR 1.75, 95% CI 1.15; 2.68) and psychopathology (beta 3.36, 95% CI 0.68; 6.04) at age 18, but only the association with PTSD held when adjusted for confounders. Conclusions Our findings suggest a need to develop targeted assessments and evidence-based treatments for PTSD to meet the needs of children with high autistic traits. However, whether our findings extend to diagnosed autistic children requires further investigation. En ligne : https://doi.org/10.1111/jcpp.14163 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] Autistic traits in childhood and post-traumatic stress disorder as young adults: a cohort study [texte imprimé] / Alice M. G. QUINTON, Auteur ; Freya RUMBALL, Auteur ; Angelica RONALD, Auteur ; Helen L. FISHER, Auteur ; Louise ARSENEAULT, Auteur ; Francesca HAPPE, Auteur ; Andrea DANESE, Auteur . - p.1514-1525. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1514-1525 Mots-clés : Autism  autism spectrum  trauma  PTSD  psychopathology Index. décimale : PER Périodiques Résumé : Background Despite the higher prevalence of childhood traumatic experiences and post-traumatic stress disorder (PTSD) in autistic adults, research on trauma-related psychopathology and autistic traits in young people is lacking. This study examined if high autistic traits in childhood predispose individuals to traumatic experiences, the development of PTSD and general psychopathology, and greater functional impairment by age 18, in both the general population and a subsample of trauma-exposed young people. Methods Data were utilised from the Environmental Risk (E-Risk) Longitudinal Twin Study, a nationally representative cohort of 2,232 same-sex twins born in 1994 1995 across England and Wales. Participants were a subset of children whose parents completed the Childhood Autism Spectrum Test (CAST), during assessments at ages 8, 9 and/or 12 years (N 1,504). We tested associations between autistic traits in childhood and age-18 reports of lifetime trauma exposure, lifetime PTSD diagnosis, general psychopathology (?p-factor?) and NEET status (?not in employment, education or training?). Analyses were conducted controlling for sex, family socioeconomic status (SES), intelligence quotient (IQ) and accounting for family clustering. Results Higher autistic traits in childhood were significantly associated with greater reports of lifetime trauma exposure (Odd Ratio [OR] 1.26, 95% Confidence Intervals [CI] 1.03; 1.54), lifetime PTSD diagnosis (OR 1.91, 95% CI 1.29; 2.82), general psychopathology (beta 3.22, 95% CI 1.84; 4.60) and NEET status (OR 1.48, 95% CI 1.05; 2.09) at age 18. Only the associations of autistic traits with PTSD and general psychopathology were robust to adjustment for potential confounders. Among trauma-exposed children, autistic traits were also significantly associated with lifetime PTSD diagnosis (OR 1.75, 95% CI 1.15; 2.68) and psychopathology (beta 3.36, 95% CI 0.68; 6.04) at age 18, but only the association with PTSD held when adjusted for confounders. Conclusions Our findings suggest a need to develop targeted assessments and evidence-based treatments for PTSD to meet the needs of children with high autistic traits. However, whether our findings extend to diagnosed autistic children requires further investigation. En ligne : https://doi.org/10.1111/jcpp.14163 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568

Diagnosing autism spectrum disorder in community settings using the Development and Well-Being Assessment: validation in a UK population-based twin sample / Fiona S. MCEWEN in Journal of Child Psychology and Psychiatry, 57-2 (February 2016)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 57-2 (February 2016) . - p.161-170 Titre : Diagnosing autism spectrum disorder in community settings using the Development and Well-Being Assessment: validation in a UK population-based twin sample Type de document : texte imprimé Auteurs : Fiona S. MCEWEN, Auteur ; Catherine S. STEWART, Auteur ; Emma COLVERT, Auteur ; Emma WOODHOUSE, Auteur ; Sarah CURRAN, Auteur ; Nicola GILLAN, Auteur ; Victoria HALLETT, Auteur ; Stephanie LIETZ, Auteur ; Tracy GARNETT, Auteur ; Angelica RONALD, Auteur ; Declan MURPHY, Auteur ; Francesca HAPPE, Auteur ; Patrick BOLTON, Auteur Article en page(s) : p.161-170 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  adolescence  assessment  diagnosis Index. décimale : PER Périodiques Résumé : Background Increasing numbers of people are being referred for the assessment of autism spectrum disorder (ASD). The NICE (UK) and the American Academy of Pediatrics recommend gathering a developmental history using a tool that operationalises ICD/DSM criteria. However, the best-established diagnostic interview instruments are time consuming, costly and rarely used outside national specialist centres. What is needed is a brief, cost-effective measure validated in community settings. We tested the Development and Well-Being Assessment (DAWBA) for diagnosing ASD in a sample of children/adolescents representative of those presenting in community mental health settings. Methods A general population sample of twins (TEDS) was screened and 276 adolescents were selected as at low (CAST score < 12; n = 164) or high risk for ASD (CAST score ≥ 15 and/or parent reported that ASD suspected/previously diagnosed; n = 112). Parents completed the ASD module of the DAWBA interview by telephone or online. Families were visited at home: the ADI-R and autism diagnostic observation schedule (ADOS) were completed to allow a best-estimate research diagnosis of ASD to be made. Results Development and Well-Being Assessment ASD symptom scores correlated highly with ADI-R algorithm scores (ρ = .82, p < .001). Good sensitivity (0.88) and specificity (0.85) were achieved using DAWBA computerised algorithms. Clinician review of responses to DAWBA questions minimally changed sensitivity (0.86) and specificity (0.87). Positive (0.82–0.95) and negative (0.90) predictive values were high. Eighty-six per cent of children were correctly classified. Performance was improved by using it in conjunction with the ADOS. Conclusions The DAWBA is a brief structured interview that showed good sensitivity and specificity in this general population sample. It requires little training, is easy to administer (online or by interview) and diagnosis is aided by an algorithm. It holds promise as a tool for assisting with assessment in community settings and may help services implement the recommendations made by NICE and the American Academy of Pediatrics regarding diagnosis of young people on the autism spectrum. En ligne : http://dx.doi.org/10.1111/jcpp.12447 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=280 [article] Diagnosing autism spectrum disorder in community settings using the Development and Well-Being Assessment: validation in a UK population-based twin sample [texte imprimé] / Fiona S. MCEWEN, Auteur ; Catherine S. STEWART, Auteur ; Emma COLVERT, Auteur ; Emma WOODHOUSE, Auteur ; Sarah CURRAN, Auteur ; Nicola GILLAN, Auteur ; Victoria HALLETT, Auteur ; Stephanie LIETZ, Auteur ; Tracy GARNETT, Auteur ; Angelica RONALD, Auteur ; Declan MURPHY, Auteur ; Francesca HAPPE, Auteur ; Patrick BOLTON, Auteur . - p.161-170. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 57-2 (February 2016) . - p.161-170 Mots-clés : Autism spectrum disorder  adolescence  assessment  diagnosis Index. décimale : PER Périodiques Résumé : Background Increasing numbers of people are being referred for the assessment of autism spectrum disorder (ASD). The NICE (UK) and the American Academy of Pediatrics recommend gathering a developmental history using a tool that operationalises ICD/DSM criteria. However, the best-established diagnostic interview instruments are time consuming, costly and rarely used outside national specialist centres. What is needed is a brief, cost-effective measure validated in community settings. We tested the Development and Well-Being Assessment (DAWBA) for diagnosing ASD in a sample of children/adolescents representative of those presenting in community mental health settings. Methods A general population sample of twins (TEDS) was screened and 276 adolescents were selected as at low (CAST score < 12; n = 164) or high risk for ASD (CAST score ≥ 15 and/or parent reported that ASD suspected/previously diagnosed; n = 112). Parents completed the ASD module of the DAWBA interview by telephone or online. Families were visited at home: the ADI-R and autism diagnostic observation schedule (ADOS) were completed to allow a best-estimate research diagnosis of ASD to be made. Results Development and Well-Being Assessment ASD symptom scores correlated highly with ADI-R algorithm scores (ρ = .82, p < .001). Good sensitivity (0.88) and specificity (0.85) were achieved using DAWBA computerised algorithms. Clinician review of responses to DAWBA questions minimally changed sensitivity (0.86) and specificity (0.87). Positive (0.82–0.95) and negative (0.90) predictive values were high. Eighty-six per cent of children were correctly classified. Performance was improved by using it in conjunction with the ADOS. Conclusions The DAWBA is a brief structured interview that showed good sensitivity and specificity in this general population sample. It requires little training, is easy to administer (online or by interview) and diagnosis is aided by an algorithm. It holds promise as a tool for assisting with assessment in community settings and may help services implement the recommendations made by NICE and the American Academy of Pediatrics regarding diagnosis of young people on the autism spectrum. En ligne : http://dx.doi.org/10.1111/jcpp.12447 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=280

Editorial: Are government early years learning and development frameworks evidence-based? A scientist's perspective / Angelica RONALD in Journal of Child Psychology and Psychiatry, 65-5 (May 2024)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 65-5 (May 2024) . - p.591-593 Titre : Editorial: Are government early years learning and development frameworks evidence-based? A scientist's perspective Type de document : texte imprimé Auteurs : Angelica RONALD, Auteur Article en page(s) : p.591-593 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Not all young children attend nurseries, childminders or other group settings before they start school, but many do. It is common for countries to set out a framework to guide practice for early years providers (such as nurseries) to follow. The conundrum regarding these frameworks for young children is that proving evidence of a causal link between early environments and later outcomes is very challenging scientifically. So how do governments choose what learning and development practices and goals to make mandatory for childcare providers? And is it realistic to expect early years providers to meet the legal requirements that these frameworks impose? We do not know which learning and development practices impact positively on later outcomes, and we certainly do not know if there is a one-size-fits-all approach for an early years framework that is guaranteed to work. En ligne : https://doi.org/10.1111/jcpp.13983 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=526 [article] Editorial: Are government early years learning and development frameworks evidence-based? A scientist's perspective [texte imprimé] / Angelica RONALD, Auteur . - p.591-593. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 65-5 (May 2024) . - p.591-593 Index. décimale : PER Périodiques Résumé : Not all young children attend nurseries, childminders or other group settings before they start school, but many do. It is common for countries to set out a framework to guide practice for early years providers (such as nurseries) to follow. The conundrum regarding these frameworks for young children is that proving evidence of a causal link between early environments and later outcomes is very challenging scientifically. So how do governments choose what learning and development practices and goals to make mandatory for childcare providers? And is it realistic to expect early years providers to meet the legal requirements that these frameworks impose? We do not know which learning and development practices impact positively on later outcomes, and we certainly do not know if there is a one-size-fits-all approach for an early years framework that is guaranteed to work. En ligne : https://doi.org/10.1111/jcpp.13983 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=526

Editorial: Beyond the usual suspects - broadening the scope of environmental influences in child and adolescent mental health research / Angelica RONALD in Journal of Child Psychology and Psychiatry, 66-5 (May 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-5 (May 2025) . - p.609-611 Titre : Editorial: Beyond the usual suspects - broadening the scope of environmental influences in child and adolescent mental health research Type de document : texte imprimé Auteurs : Angelica RONALD, Auteur Article en page(s) : p.609-611 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : When we think about which environmental influences affect children and young people's mental health, answers that are 'close to home' tend to come to mind, such as relationships, screen time, bullying, stressful life events and poverty. These same factors are also often prioritised in child and adolescent mental health research. More distal factors receive less attention, such as the air we breathe, the materials in our built environment, and the cultural and social norms of the societies in which we live. These factors are embedded in the very structure of our built and social environments, but may be harder to 'imagine' as being important, perhaps because they feel less tangible. Findings in this issue of the journal highlight the relevance of these factors for child and adolescent mental health. This editorial will reflect on the importance of these findings and then turn to consider how physical and sociocultural factors can be better integrated in research on child and adolescent mental health, by incorporating novel data sources, diversifying samples and by capturing multiple levels of analysis. En ligne : https://doi.org/10.1111/jcpp.14165 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=554 [article] Editorial: Beyond the usual suspects - broadening the scope of environmental influences in child and adolescent mental health research [texte imprimé] / Angelica RONALD, Auteur . - p.609-611. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-5 (May 2025) . - p.609-611 Index. décimale : PER Périodiques Résumé : When we think about which environmental influences affect children and young people's mental health, answers that are 'close to home' tend to come to mind, such as relationships, screen time, bullying, stressful life events and poverty. These same factors are also often prioritised in child and adolescent mental health research. More distal factors receive less attention, such as the air we breathe, the materials in our built environment, and the cultural and social norms of the societies in which we live. These factors are embedded in the very structure of our built and social environments, but may be harder to 'imagine' as being important, perhaps because they feel less tangible. Findings in this issue of the journal highlight the relevance of these factors for child and adolescent mental health. This editorial will reflect on the importance of these findings and then turn to consider how physical and sociocultural factors can be better integrated in research on child and adolescent mental health, by incorporating novel data sources, diversifying samples and by capturing multiple levels of analysis. En ligne : https://doi.org/10.1111/jcpp.14165 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=554

Editorial: Polygenic scores in child and adolescent psychiatry - strengths, weaknesses, opportunities and threats / Angelica RONALD in Journal of Child Psychology and Psychiatry, 61-5 (May 2020)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 61-5 (May 2020) . - p.519-521 Titre : Editorial: Polygenic scores in child and adolescent psychiatry - strengths, weaknesses, opportunities and threats Type de document : texte imprimé Auteurs : Angelica RONALD, Auteur Article en page(s) : p.519-521 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Polygenic scores estimate an individual's genetic liability for a particular disorder or trait. They are based on current knowledge of the trait's genetic architecture and focus on common genetic variants. In this editorial, I will discuss some of the strengths, weaknesses, opportunities and threats (SWOT) to polygenic scores within the context of child and adolescent psychiatry. I consider how the potential application of polygenic scores in health settings has some parallels with existing practices, but that polygenic scores also undoubtedly raise unique challenges. This SWOT analysis is accompanied by discussion of some new findings using polygenic scores in this issue of Journal of Child Psychology and Psychiatry. En ligne : http://dx.doi.org/10.1111/jcpp.13246 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=422 [article] Editorial: Polygenic scores in child and adolescent psychiatry - strengths, weaknesses, opportunities and threats [texte imprimé] / Angelica RONALD, Auteur . - p.519-521. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 61-5 (May 2020) . - p.519-521 Index. décimale : PER Périodiques Résumé : Polygenic scores estimate an individual's genetic liability for a particular disorder or trait. They are based on current knowledge of the trait's genetic architecture and focus on common genetic variants. In this editorial, I will discuss some of the strengths, weaknesses, opportunities and threats (SWOT) to polygenic scores within the context of child and adolescent psychiatry. I consider how the potential application of polygenic scores in health settings has some parallels with existing practices, but that polygenic scores also undoubtedly raise unique challenges. This SWOT analysis is accompanied by discussion of some new findings using polygenic scores in this issue of Journal of Child Psychology and Psychiatry. En ligne : http://dx.doi.org/10.1111/jcpp.13246 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=422

Editorial: Transdiagnostic research: transitory or transformative? / Angelica RONALD in Journal of Child Psychology and Psychiatry, 63-7 (July 2022)  

Permalink

Editorial: What's in a name? Drawing on the examples of autism and schizophrenia, some reflections on diagnostic labels and their future role in child and adolescent psychiatry / Angelica RONALD in Journal of Child Psychology and Psychiatry, 64-7 (July 2023)  

Permalink

Evidence for overlapping genetic influences on autistic and ADHD behaviours in a community twin sample / Angelica RONALD in Journal of Child Psychology and Psychiatry, 49-5 (May 2008)  

Permalink

Explaining the influence of non-shared environment (NSE) on symptoms of behaviour problems from preschool to adulthood: mind the missing NSE gap / Agnieszka GIDZIELA in Journal of Child Psychology and Psychiatry, 64-5 (May 2023)  

Permalink

Exploring anxiety symptoms in a large-scale twin study of children with autism spectrum disorders, their co-twins and controls / Victoria HALLETT in Journal of Child Psychology and Psychiatry, 54-11 (November 2013)  

Permalink

Genetic and phenotypic heterogeneity in early neurodevelopmental traits in the Norwegian Mother, Father and Child Cohort Study / Laura HEGEMANN in Molecular Autism, 15 (2024)  

Permalink

Is quality of life related to high autistic traits, high ADHD traits and their Interaction? Evidence from a Young-Adult Community-Based twin sample / Simone J. CAPP in Journal of Autism and Developmental Disorders, 53-9 (September 2023)  

Permalink

A longitudinal twin study of the association between childhood autistic traits and psychotic experiences in adolescence / Mark J. TAYLOR in Molecular Autism, (July 2015)  

Permalink

A multivariate genetic analysis of anxiety sensitivity, environmental sensitivity and reported life events in adolescents / Alicia J. PEEL in Journal of Child Psychology and Psychiatry, 64-2 (February 2023)  

Permalink

No major effect of twinning on autistic traits / Sarah CURRAN in Autism Research, 4-5 (October 2011)  

Permalink

---

1 2 (1 - 15 / 24) Par page : 25 50 100 200