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Auteur Robert T. SCHULTZ |
Documents disponibles écrits par cet auteur (78)
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Measuring social attention and motivation in autism spectrum disorder using eye-tracking: Stimulus type matters / Coralie CHEVALLIER in Autism Research, 8-5 (October 2015)
[article]
Titre : Measuring social attention and motivation in autism spectrum disorder using eye-tracking: Stimulus type matters Type de document : Texte imprimé et/ou numérique Auteurs : Coralie CHEVALLIER, Auteur ; Julia PARISH-MORRIS, Auteur ; Alana MCVEY, Auteur ; Keiran M. RUMP, Auteur ; Noah J. SASSON, Auteur ; John D. HERRINGTON, Auteur ; Robert T. SCHULTZ, Auteur Article en page(s) : p.620-628 Langues : Anglais (eng) Mots-clés : social attention autism spectrum disorder eye-tracking social motivation methodology face processing Index. décimale : PER Périodiques Résumé : Autism Spectrum Disorder (ASD) is characterized by social impairments that have been related to deficits in social attention, including diminished gaze to faces. Eye-tracking studies are commonly used to examine social attention and social motivation in ASD, but they vary in sensitivity. In this study, we hypothesized that the ecological nature of the social stimuli would affect participants' social attention, with gaze behavior during more naturalistic scenes being most predictive of ASD vs. typical development. Eighty-one children with and without ASD participated in three eye-tracking tasks that differed in the ecological relevance of the social stimuli. In the “Static Visual Exploration” task, static images of objects and people were presented; in the “Dynamic Visual Exploration” task, video clips of individual faces and objects were presented side-by-side; in the “Interactive Visual Exploration” task, video clips of children playing with objects in a naturalistic context were presented. Our analyses uncovered a three-way interaction between Task, Social vs. Object Stimuli, and Diagnosis. This interaction was driven by group differences on one task only—the Interactive task. Bayesian analyses confirmed that the other two tasks were insensitive to group membership. In addition, receiver operating characteristic analyses demonstrated that, unlike the other two tasks, the Interactive task had significant classification power. The ecological relevance of social stimuli is an important factor to consider for eye-tracking studies aiming to measure social attention and motivation in ASD. Autism Res 2015, 8: 620–628. © 2015 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1479 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=270
in Autism Research > 8-5 (October 2015) . - p.620-628[article] Measuring social attention and motivation in autism spectrum disorder using eye-tracking: Stimulus type matters [Texte imprimé et/ou numérique] / Coralie CHEVALLIER, Auteur ; Julia PARISH-MORRIS, Auteur ; Alana MCVEY, Auteur ; Keiran M. RUMP, Auteur ; Noah J. SASSON, Auteur ; John D. HERRINGTON, Auteur ; Robert T. SCHULTZ, Auteur . - p.620-628.
Langues : Anglais (eng)
in Autism Research > 8-5 (October 2015) . - p.620-628
Mots-clés : social attention autism spectrum disorder eye-tracking social motivation methodology face processing Index. décimale : PER Périodiques Résumé : Autism Spectrum Disorder (ASD) is characterized by social impairments that have been related to deficits in social attention, including diminished gaze to faces. Eye-tracking studies are commonly used to examine social attention and social motivation in ASD, but they vary in sensitivity. In this study, we hypothesized that the ecological nature of the social stimuli would affect participants' social attention, with gaze behavior during more naturalistic scenes being most predictive of ASD vs. typical development. Eighty-one children with and without ASD participated in three eye-tracking tasks that differed in the ecological relevance of the social stimuli. In the “Static Visual Exploration” task, static images of objects and people were presented; in the “Dynamic Visual Exploration” task, video clips of individual faces and objects were presented side-by-side; in the “Interactive Visual Exploration” task, video clips of children playing with objects in a naturalistic context were presented. Our analyses uncovered a three-way interaction between Task, Social vs. Object Stimuli, and Diagnosis. This interaction was driven by group differences on one task only—the Interactive task. Bayesian analyses confirmed that the other two tasks were insensitive to group membership. In addition, receiver operating characteristic analyses demonstrated that, unlike the other two tasks, the Interactive task had significant classification power. The ecological relevance of social stimuli is an important factor to consider for eye-tracking studies aiming to measure social attention and motivation in ASD. Autism Res 2015, 8: 620–628. © 2015 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1479 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=270 Natural language markers of social phenotype in girls with autism / A. SONG in Journal of Child Psychology and Psychiatry, 62-8 (August 2021)
[article]
Titre : Natural language markers of social phenotype in girls with autism Type de document : Texte imprimé et/ou numérique Auteurs : A. SONG, Auteur ; M. COLA, Auteur ; S. PLATE, Auteur ; V. PETRULLA, Auteur ; L. YANKOWITZ, Auteur ; J. PANDEY, Auteur ; Robert T. SCHULTZ, Auteur ; Julia PARISH-MORRIS, Auteur Article en page(s) : p.949-960 Langues : Anglais (eng) Mots-clés : Adolescent Autism Spectrum Disorder Autistic Disorder Child Female Humans Language Male Motivation Phenotype Autism spectrum condition language pronouns sex differences social phenotype Index. décimale : PER Périodiques Résumé : BACKGROUND: Girls with autism spectrum condition (ASC) are chronically underdiagnosed compared to boys, which may be due to poorly understood sex differences in a variety of domains, including social interest and motivation. In this study, we use natural language processing to identify objective markers of social phenotype that are easily obtained from a brief conversation with a nonexpert. METHODS: 87 school-aged children and adolescents with ASC (17 girls, 33 boys) or typical development (TD; 15 girls, 22 boys) were matched on age (mean = 11.35 years), IQ estimates (mean = 107), and - for ASC participants - level of social impairment. Participants engaged in an informal 5-min 'get to know you' conversation with a nonexpert conversation partner. To measure attention to social groups, we analyzed first-person plural pronoun variants (e.g., 'we' and 'us') and third-person plural pronoun variants (e.g., 'they' and 'them'). RESULTS: Consistent with prior research suggesting greater social motivation in autistic girls, autistic girls talked more about social groups than did ASC boys. Compared to TD girls, autistic girls demonstrated atypically heightened discussion of groups they were not a part of ('they', 'them'), indicating potential awareness of social exclusion. Pronoun use predicted individual differences in the social phenotypes of autistic girls. CONCLUSIONS: Relatively heightened but atypical social group focus is evident in autistic girls during spontaneous conversation, which contrasts with patterns observed in autistic boys and TD girls. Quantifying subtle linguistic differences in verbally fluent autistic girls is an important step toward improved identification and support for this understudied sector of the autism spectrum. En ligne : http://dx.doi.org/10.1111/jcpp.13348 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456
in Journal of Child Psychology and Psychiatry > 62-8 (August 2021) . - p.949-960[article] Natural language markers of social phenotype in girls with autism [Texte imprimé et/ou numérique] / A. SONG, Auteur ; M. COLA, Auteur ; S. PLATE, Auteur ; V. PETRULLA, Auteur ; L. YANKOWITZ, Auteur ; J. PANDEY, Auteur ; Robert T. SCHULTZ, Auteur ; Julia PARISH-MORRIS, Auteur . - p.949-960.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 62-8 (August 2021) . - p.949-960
Mots-clés : Adolescent Autism Spectrum Disorder Autistic Disorder Child Female Humans Language Male Motivation Phenotype Autism spectrum condition language pronouns sex differences social phenotype Index. décimale : PER Périodiques Résumé : BACKGROUND: Girls with autism spectrum condition (ASC) are chronically underdiagnosed compared to boys, which may be due to poorly understood sex differences in a variety of domains, including social interest and motivation. In this study, we use natural language processing to identify objective markers of social phenotype that are easily obtained from a brief conversation with a nonexpert. METHODS: 87 school-aged children and adolescents with ASC (17 girls, 33 boys) or typical development (TD; 15 girls, 22 boys) were matched on age (mean = 11.35 years), IQ estimates (mean = 107), and - for ASC participants - level of social impairment. Participants engaged in an informal 5-min 'get to know you' conversation with a nonexpert conversation partner. To measure attention to social groups, we analyzed first-person plural pronoun variants (e.g., 'we' and 'us') and third-person plural pronoun variants (e.g., 'they' and 'them'). RESULTS: Consistent with prior research suggesting greater social motivation in autistic girls, autistic girls talked more about social groups than did ASC boys. Compared to TD girls, autistic girls demonstrated atypically heightened discussion of groups they were not a part of ('they', 'them'), indicating potential awareness of social exclusion. Pronoun use predicted individual differences in the social phenotypes of autistic girls. CONCLUSIONS: Relatively heightened but atypical social group focus is evident in autistic girls during spontaneous conversation, which contrasts with patterns observed in autistic boys and TD girls. Quantifying subtle linguistic differences in verbally fluent autistic girls is an important step toward improved identification and support for this understudied sector of the autism spectrum. En ligne : http://dx.doi.org/10.1111/jcpp.13348 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456 Neural circuitry at age 6 months associated with later repetitive behavior and sensory responsiveness in autism / J. J. WOLFF in Molecular Autism, 8 (2017)
[article]
Titre : Neural circuitry at age 6 months associated with later repetitive behavior and sensory responsiveness in autism Type de document : Texte imprimé et/ou numérique Auteurs : J. J. WOLFF, Auteur ; M. R. SWANSON, Auteur ; J. T. ELISON, Auteur ; G. GERIG, Auteur ; J. R. PRUETT, Auteur ; M. A. STYNER, Auteur ; C. VACHET, Auteur ; Kelly N. BOTTERON, Auteur ; Stephen R. DAGER, Auteur ; A. M. ESTES, Auteur ; Heather C. HAZLETT, Auteur ; Robert T. SCHULTZ, Auteur ; M. D. SHEN, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; J. PIVEN, Auteur Article en page(s) : 8p. Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnostic imaging/*psychology Brain/diagnostic imaging/*physiology Brain Mapping/*methods Child, Preschool Diffusion Tensor Imaging/*methods Female Humans Infant Longitudinal Studies Male Stereotyped Behavior/*physiology *Autism *Diffusion tensor imaging *Infant *Longitudinal *Repetitive behavior *White matter Index. décimale : PER Périodiques Résumé : BACKGROUND: Restricted and repetitive behaviors are defining features of autism spectrum disorder (ASD). Under revised diagnostic criteria for ASD, this behavioral domain now includes atypical responses to sensory stimuli. To date, little is known about the neural circuitry underlying these features of ASD early in life. METHODS: Longitudinal diffusion tensor imaging data were collected from 217 infants at high familial risk for ASD. Forty-four of these infants were diagnosed with ASD at age 2. Targeted cortical, cerebellar, and striatal white matter pathways were defined and measured at ages 6, 12, and 24 months. Dependent variables included the Repetitive Behavior Scale-Revised and the Sensory Experiences Questionnaire. RESULTS: Among children diagnosed with ASD, repetitive behaviors and sensory response patterns were strongly correlated, even when accounting for developmental level or social impairment. Longitudinal analyses indicated that the genu and cerebellar pathways were significantly associated with both repetitive behaviors and sensory responsiveness but not social deficits. At age 6 months, fractional anisotropy in the genu significantly predicted repetitive behaviors and sensory responsiveness at age 2. Cerebellar pathways significantly predicted later sensory responsiveness. Exploratory analyses suggested a possible disordinal interaction based on diagnostic status for the association between fractional anisotropy and repetitive behavior. CONCLUSIONS: Our findings suggest that restricted and repetitive behaviors contributing to a diagnosis of ASD at age 2 years are associated with structural properties of callosal and cerebellar white matter pathways measured during infancy and toddlerhood. We further identified that repetitive behaviors and unusual sensory response patterns co-occur and share common brain-behavior relationships. These results were strikingly specific given the absence of association between targeted pathways and social deficits. En ligne : http://dx.doi.org/10.1186/s13229-017-0126-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=331
in Molecular Autism > 8 (2017) . - 8p.[article] Neural circuitry at age 6 months associated with later repetitive behavior and sensory responsiveness in autism [Texte imprimé et/ou numérique] / J. J. WOLFF, Auteur ; M. R. SWANSON, Auteur ; J. T. ELISON, Auteur ; G. GERIG, Auteur ; J. R. PRUETT, Auteur ; M. A. STYNER, Auteur ; C. VACHET, Auteur ; Kelly N. BOTTERON, Auteur ; Stephen R. DAGER, Auteur ; A. M. ESTES, Auteur ; Heather C. HAZLETT, Auteur ; Robert T. SCHULTZ, Auteur ; M. D. SHEN, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; J. PIVEN, Auteur . - 8p.
Langues : Anglais (eng)
in Molecular Autism > 8 (2017) . - 8p.
Mots-clés : Autism Spectrum Disorder/diagnostic imaging/*psychology Brain/diagnostic imaging/*physiology Brain Mapping/*methods Child, Preschool Diffusion Tensor Imaging/*methods Female Humans Infant Longitudinal Studies Male Stereotyped Behavior/*physiology *Autism *Diffusion tensor imaging *Infant *Longitudinal *Repetitive behavior *White matter Index. décimale : PER Périodiques Résumé : BACKGROUND: Restricted and repetitive behaviors are defining features of autism spectrum disorder (ASD). Under revised diagnostic criteria for ASD, this behavioral domain now includes atypical responses to sensory stimuli. To date, little is known about the neural circuitry underlying these features of ASD early in life. METHODS: Longitudinal diffusion tensor imaging data were collected from 217 infants at high familial risk for ASD. Forty-four of these infants were diagnosed with ASD at age 2. Targeted cortical, cerebellar, and striatal white matter pathways were defined and measured at ages 6, 12, and 24 months. Dependent variables included the Repetitive Behavior Scale-Revised and the Sensory Experiences Questionnaire. RESULTS: Among children diagnosed with ASD, repetitive behaviors and sensory response patterns were strongly correlated, even when accounting for developmental level or social impairment. Longitudinal analyses indicated that the genu and cerebellar pathways were significantly associated with both repetitive behaviors and sensory responsiveness but not social deficits. At age 6 months, fractional anisotropy in the genu significantly predicted repetitive behaviors and sensory responsiveness at age 2. Cerebellar pathways significantly predicted later sensory responsiveness. Exploratory analyses suggested a possible disordinal interaction based on diagnostic status for the association between fractional anisotropy and repetitive behavior. CONCLUSIONS: Our findings suggest that restricted and repetitive behaviors contributing to a diagnosis of ASD at age 2 years are associated with structural properties of callosal and cerebellar white matter pathways measured during infancy and toddlerhood. We further identified that repetitive behaviors and unusual sensory response patterns co-occur and share common brain-behavior relationships. These results were strikingly specific given the absence of association between targeted pathways and social deficits. En ligne : http://dx.doi.org/10.1186/s13229-017-0126-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=331 Neural Correlates of Set-Shifting in Children With Autism / Benjamin E. YERYS in Autism Research, 8-4 (August 2015)
[article]
Titre : Neural Correlates of Set-Shifting in Children With Autism Type de document : Texte imprimé et/ou numérique Auteurs : Benjamin E. YERYS, Auteur ; Ligia ANTEZANA, Auteur ; Rachel WEINBLATT, Auteur ; Kathryn F. JANKOWSKI, Auteur ; John STRANG, Auteur ; Chandan J. VAIDYA, Auteur ; Robert T. SCHULTZ, Auteur ; William D. GAILLARD, Auteur ; Lauren KENWORTHY, Auteur Article en page(s) : p.386-397 Langues : Anglais (eng) Mots-clés : autism cognitive control set-shifting functional magnetic resonance imaging cingulate prefrontal cortex Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is often associated with high levels of inflexible thinking and rigid behavior. The neural correlates of these behaviors have been investigated in adults and older adolescents, but not children. Prior studies utilized set-shifting tasks that engaged multiple levels of shifting, and depended on learning abstract rules and establishing a strong prepotent bias. These additional demands complicate simple interpretations of the results. We used functional magnetic resonance imaging (fMRI) to investigate the neural correlates of set-shifting in 20 children (ages 7–14) with ASD and 19 typically developing, matched, control children. Participants completed a set-shifting task that minimized nonshifting task demands through the use of concrete instructions that provide spatial mapping of stimuli-responses. The shift/stay sets were given an equal number of trials to limit the prepotent bias. Both groups showed an equivalent “switch cost,” responding less accurately and slower to Switch stimuli than Stay stimuli, although the ASD group was less accurate overall. Both groups showed activation in prefrontal, striatal, parietal, and cerebellum regions known to govern effective set-shifts. Compared to controls, children with ASD demonstrated decreased activation of the right middle temporal gyrus across all trials, but increased activation in the mid-dorsal cingulate cortex/superior frontal gyrus, left middle frontal, and right inferior frontal gyri during the Switch vs. Stay contrast. The successful behavioral switching performance of children with ASD comes at the cost of requiring greater engagement of frontal regions, suggesting less efficiency at this lowest level of shifting. Autism Res 2015, 8: 386–397. © 2015 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1454 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=268
in Autism Research > 8-4 (August 2015) . - p.386-397[article] Neural Correlates of Set-Shifting in Children With Autism [Texte imprimé et/ou numérique] / Benjamin E. YERYS, Auteur ; Ligia ANTEZANA, Auteur ; Rachel WEINBLATT, Auteur ; Kathryn F. JANKOWSKI, Auteur ; John STRANG, Auteur ; Chandan J. VAIDYA, Auteur ; Robert T. SCHULTZ, Auteur ; William D. GAILLARD, Auteur ; Lauren KENWORTHY, Auteur . - p.386-397.
Langues : Anglais (eng)
in Autism Research > 8-4 (August 2015) . - p.386-397
Mots-clés : autism cognitive control set-shifting functional magnetic resonance imaging cingulate prefrontal cortex Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is often associated with high levels of inflexible thinking and rigid behavior. The neural correlates of these behaviors have been investigated in adults and older adolescents, but not children. Prior studies utilized set-shifting tasks that engaged multiple levels of shifting, and depended on learning abstract rules and establishing a strong prepotent bias. These additional demands complicate simple interpretations of the results. We used functional magnetic resonance imaging (fMRI) to investigate the neural correlates of set-shifting in 20 children (ages 7–14) with ASD and 19 typically developing, matched, control children. Participants completed a set-shifting task that minimized nonshifting task demands through the use of concrete instructions that provide spatial mapping of stimuli-responses. The shift/stay sets were given an equal number of trials to limit the prepotent bias. Both groups showed an equivalent “switch cost,” responding less accurately and slower to Switch stimuli than Stay stimuli, although the ASD group was less accurate overall. Both groups showed activation in prefrontal, striatal, parietal, and cerebellum regions known to govern effective set-shifts. Compared to controls, children with ASD demonstrated decreased activation of the right middle temporal gyrus across all trials, but increased activation in the mid-dorsal cingulate cortex/superior frontal gyrus, left middle frontal, and right inferior frontal gyri during the Switch vs. Stay contrast. The successful behavioral switching performance of children with ASD comes at the cost of requiring greater engagement of frontal regions, suggesting less efficiency at this lowest level of shifting. Autism Res 2015, 8: 386–397. © 2015 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.1454 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=268 Neuroimaging Research in Autism: The Next Decade / Robert T. SCHULTZ in Autism Research, 1-6 (December 2008)
[article]
Titre : Neuroimaging Research in Autism: The Next Decade Type de document : Texte imprimé et/ou numérique Auteurs : Robert T. SCHULTZ, Auteur Année de publication : 2008 Article en page(s) : p.317-319 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.58 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=934
in Autism Research > 1-6 (December 2008) . - p.317-319[article] Neuroimaging Research in Autism: The Next Decade [Texte imprimé et/ou numérique] / Robert T. SCHULTZ, Auteur . - 2008 . - p.317-319.
Langues : Anglais (eng)
in Autism Research > 1-6 (December 2008) . - p.317-319
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.58 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=934 Offering to Share: How to Put Heads Together in Autism Neuroimaging / Matthew K. BELMONTE in Journal of Autism and Developmental Disorders, 38-1 (January 2008)
PermalinkOptimal outcome in individuals with a history of autism / Deborah A. FEIN in Journal of Child Psychology and Psychiatry, 54-2 (February 2013)
PermalinkPermalinkParent Support of Preschool Peer Relationships in Younger Siblings of Children with Autism Spectrum Disorder / A. ESTES in Journal of Autism and Developmental Disorders, 48-4 (April 2018)
PermalinkPoor fine-motor and visuospatial skills predict persistence of pediatric-onset obsessive-compulsive disorder into adulthood / Michael H. BLOCH in Journal of Child Psychology and Psychiatry, 52-9 (September 2011)
PermalinkPotential Risk Factors for the Development of Self-Injurious Behavior among Infants at Risk for Autism Spectrum Disorder / Adele F. DIMIAN in Journal of Autism and Developmental Disorders, 47-5 (May 2017)
PermalinkPsychiatric Symptoms in Youth with a History of Autism and Optimal Outcome / Alyssa ORINSTEIN in Journal of Autism and Developmental Disorders, 45-11 (November 2015)
PermalinkRelations of Restricted and Repetitive Behaviors to Social Skills in Toddlers with Autism / Pang CHAXIONG in Journal of Autism and Developmental Disorders, 52-4 (April 2022)
PermalinkReliability and validity of the Pediatric Anxiety Rating Scale modified for autism spectrum disorder / Brenna B MADDOX in Autism, 24-7 (October 2020)
PermalinkReplication and Comparison of the Newly Proposed ADOS-2, Module 4 Algorithm in ASD Without ID: A Multi-site Study / Cara E. PUGLIESE in Journal of Autism and Developmental Disorders, 45-12 (December 2015)
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