Behavioral Evaluation of Genetic Mouse Models of Autism / Mu YANG

Public ISBD in Autism Spectrum Disorders / David G. AMARAL Titre : Behavioral Evaluation of Genetic Mouse Models of Autism Type de document : Texte imprimé et/ou numérique Auteurs : Mu YANG, Auteur ; Maria Luisa SCATTONI, Auteur ; Kathryn K. CHADMAN, Auteur ; Jill L. SILVERMAN, Auteur ; Jacqueline N. CRAWLEY, Auteur Année de publication : 2011 Importance : p.906-934 Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=140 in Autism Spectrum Disorders / David G. AMARAL Behavioral Evaluation of Genetic Mouse Models of Autism [Texte imprimé et/ou numérique] / Mu YANG, Auteur ; Maria Luisa SCATTONI, Auteur ; Kathryn K. CHADMAN, Auteur ; Jill L. SILVERMAN, Auteur ; Jacqueline N. CRAWLEY, Auteur . - 2011 . - p.906-934. Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=140

Exemplaires

Code-barres	Cote	Support	Localisation	Section	Disponibilité
aucun exemplaire

Correction to: Early Detection, Diagnosis and Intervention Services for Young Children with Autism Spectrum Disorder in the European Union (ASDEU): Family and Professional Perspectives / Álvaro BEJARANO-MARTÍN in Journal of Autism and Developmental Disorders, 50-9 (September 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-9 (September 2020) . - p.3395-3396 Titre : Correction to: Early Detection, Diagnosis and Intervention Services for Young Children with Autism Spectrum Disorder in the European Union (ASDEU): Family and Professional Perspectives Type de document : Texte imprimé et/ou numérique Auteurs : Álvaro BEJARANO-MARTÍN, Auteur ; Ricardo CANAL-BEDIA, Auteur ; María MAGÁN-MAGANTO, Auteur ; Clara FERNÁNDEZ-ÁLVAREZ, Auteur ; María Victoria MARTIN-CILLEROS, Auteur ; María Cruz SÁNCHEZ-GÓMEZ, Auteur ; Patricia GARCÍA PRIMO, Auteur ; Mary ROSE-SWEENEY, Auteur ; Andrew Martin BOILSON, Auteur ; Renata LINERTOVÁ, Auteur ; Herbert ROEYERS, Auteur ; Sara VAN DER PAELT, Auteur ; Diana SCHENDEL, Auteur ; Christine WARBERG, Auteur ; Susanne CRAMER, Auteur ; Antonio NARZISI, Auteur ; Filippo MURATORI, Auteur ; Maria Luisa SCATTONI, Auteur ; Irma MOILANEN, Auteur ; Anneli YLIHERVA, Auteur ; Evald SAEMUNDSEN, Auteur ; Sigríður LOA JÓNSDÓTTIR, Auteur ; Magdalena EFRIM-BUDISTEANU, Auteur ; Aurora ARGHIR, Auteur ; Sorina Mihaela PAPUC, Auteur ; Astrid VICENTE, Auteur ; Célia RASGA, Auteur ; Bernadette ROGE, Auteur ; Quentin GUILLON, Auteur ; Sophie BADUEL, Auteur ; Johanna Xenia KAFKA, Auteur ; Luise POUSTKA, Auteur ; Oswald D. KOTHGASSNER, Auteur ; Rafal KAWA, Auteur ; Ewa PISULA, Auteur ; Tracey SELLERS, Auteur ; Manuel POSADA DE LA PAZ, Auteur Article en page(s) : p.3395-3396 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The original version of this article unfortunately contained a mistake in one of the co-author's family name. The correct name should be María Victoria Martín-Cilleros instead of María Victoria Cilleros-Martín. En ligne : http://dx.doi.org/10.1007/s10803-019-04303-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=430 [article] Correction to: Early Detection, Diagnosis and Intervention Services for Young Children with Autism Spectrum Disorder in the European Union (ASDEU): Family and Professional Perspectives [Texte imprimé et/ou numérique] / Álvaro BEJARANO-MARTÍN, Auteur ; Ricardo CANAL-BEDIA, Auteur ; María MAGÁN-MAGANTO, Auteur ; Clara FERNÁNDEZ-ÁLVAREZ, Auteur ; María Victoria MARTIN-CILLEROS, Auteur ; María Cruz SÁNCHEZ-GÓMEZ, Auteur ; Patricia GARCÍA PRIMO, Auteur ; Mary ROSE-SWEENEY, Auteur ; Andrew Martin BOILSON, Auteur ; Renata LINERTOVÁ, Auteur ; Herbert ROEYERS, Auteur ; Sara VAN DER PAELT, Auteur ; Diana SCHENDEL, Auteur ; Christine WARBERG, Auteur ; Susanne CRAMER, Auteur ; Antonio NARZISI, Auteur ; Filippo MURATORI, Auteur ; Maria Luisa SCATTONI, Auteur ; Irma MOILANEN, Auteur ; Anneli YLIHERVA, Auteur ; Evald SAEMUNDSEN, Auteur ; Sigríður LOA JÓNSDÓTTIR, Auteur ; Magdalena EFRIM-BUDISTEANU, Auteur ; Aurora ARGHIR, Auteur ; Sorina Mihaela PAPUC, Auteur ; Astrid VICENTE, Auteur ; Célia RASGA, Auteur ; Bernadette ROGE, Auteur ; Quentin GUILLON, Auteur ; Sophie BADUEL, Auteur ; Johanna Xenia KAFKA, Auteur ; Luise POUSTKA, Auteur ; Oswald D. KOTHGASSNER, Auteur ; Rafal KAWA, Auteur ; Ewa PISULA, Auteur ; Tracey SELLERS, Auteur ; Manuel POSADA DE LA PAZ, Auteur . - p.3395-3396. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-9 (September 2020) . - p.3395-3396 Index. décimale : PER Périodiques Résumé : The original version of this article unfortunately contained a mistake in one of the co-author's family name. The correct name should be María Victoria Martín-Cilleros instead of María Victoria Cilleros-Martín. En ligne : http://dx.doi.org/10.1007/s10803-019-04303-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=430

Early Detection, Diagnosis and Intervention Services for Young Children with Autism Spectrum Disorder in the European Union (ASDEU): Family and Professional Perspectives / Álvaro BEJARANO-MARTÍN in Journal of Autism and Developmental Disorders, 50-9 (September 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-9 (September 2020) . - p.3380-3394 Titre : Early Detection, Diagnosis and Intervention Services for Young Children with Autism Spectrum Disorder in the European Union (ASDEU): Family and Professional Perspectives Type de document : Texte imprimé et/ou numérique Auteurs : Álvaro BEJARANO-MARTÍN, Auteur ; Ricardo CANAL-BEDIA, Auteur ; María MAGÁN-MAGANTO, Auteur ; Clara FERNÁNDEZ-ÁLVAREZ, Auteur ; María Victoria CILLEROS-MARTÍN, Auteur ; María Cruz SÁNCHEZ-GÓMEZ, Auteur ; Patricia GARCÍA PRIMO, Auteur ; Mary ROSE-SWEENEY, Auteur ; Andrew Martin BOILSON, Auteur ; Renata LINERTOVÁ, Auteur ; Herbert ROEYERS, Auteur ; Sara VAN DER PAELT, Auteur ; Diana SCHENDEL, Auteur ; Christine WARBERG, Auteur ; Susanne CRAMER, Auteur ; Antonio NARZISI, Auteur ; Filippo MURATORI, Auteur ; Maria Luisa SCATTONI, Auteur ; Irma MOILANEN, Auteur ; Anneli YLIHERVA, Auteur ; Evald SAEMUNDSEN, Auteur ; Sigríður LOA JÓNSDÓTTIR, Auteur ; Magdalena EFRIM-BUDISTEANU, Auteur ; Aurora ARGHIR, Auteur ; Sorina Mihaela PAPUC, Auteur ; Astrid VICENTE, Auteur ; Célia RASGA, Auteur ; Bernadette ROGE, Auteur ; Quentin GUILLON, Auteur ; Sophie BADUEL, Auteur ; Johanna Xenia KAFKA, Auteur ; Luise POUSTKA, Auteur ; Oswald D. KOTHGASSNER, Auteur ; Rafal KAWA, Auteur ; Ewa PISULA, Auteur ; Tracey SELLERS, Auteur ; Manuel POSADA DE LA PAZ, Auteur Article en page(s) : p.3380-3394 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Diagnosis  Early detection  Mental health services  Patient satisfaction  Survey Index. décimale : PER Périodiques Résumé : Early services for ASD need to canvas the opinions of both parents and professionals. These opinions are seldom compared in the same research study. This study aims to ascertain the views of families and professionals on early detection, diagnosis and intervention services for young children with ASD. An online survey compiled and analysed data from 2032 respondents across 14 European countries (60.9% were parents; 39.1% professionals). Using an ordinal scale from 1 to 7, parents' opinions were more negative (mean?=?4.6; SD 2.2) compared to those of professionals (mean?=?4.9; SD 1.5) when reporting satisfaction with services. The results suggest services should take into account child's age, delays in accessing services, and active stakeholders' participation when looking to improve services. En ligne : http://dx.doi.org/10.1007/s10803-019-04253-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=430 [article] Early Detection, Diagnosis and Intervention Services for Young Children with Autism Spectrum Disorder in the European Union (ASDEU): Family and Professional Perspectives [Texte imprimé et/ou numérique] / Álvaro BEJARANO-MARTÍN, Auteur ; Ricardo CANAL-BEDIA, Auteur ; María MAGÁN-MAGANTO, Auteur ; Clara FERNÁNDEZ-ÁLVAREZ, Auteur ; María Victoria CILLEROS-MARTÍN, Auteur ; María Cruz SÁNCHEZ-GÓMEZ, Auteur ; Patricia GARCÍA PRIMO, Auteur ; Mary ROSE-SWEENEY, Auteur ; Andrew Martin BOILSON, Auteur ; Renata LINERTOVÁ, Auteur ; Herbert ROEYERS, Auteur ; Sara VAN DER PAELT, Auteur ; Diana SCHENDEL, Auteur ; Christine WARBERG, Auteur ; Susanne CRAMER, Auteur ; Antonio NARZISI, Auteur ; Filippo MURATORI, Auteur ; Maria Luisa SCATTONI, Auteur ; Irma MOILANEN, Auteur ; Anneli YLIHERVA, Auteur ; Evald SAEMUNDSEN, Auteur ; Sigríður LOA JÓNSDÓTTIR, Auteur ; Magdalena EFRIM-BUDISTEANU, Auteur ; Aurora ARGHIR, Auteur ; Sorina Mihaela PAPUC, Auteur ; Astrid VICENTE, Auteur ; Célia RASGA, Auteur ; Bernadette ROGE, Auteur ; Quentin GUILLON, Auteur ; Sophie BADUEL, Auteur ; Johanna Xenia KAFKA, Auteur ; Luise POUSTKA, Auteur ; Oswald D. KOTHGASSNER, Auteur ; Rafal KAWA, Auteur ; Ewa PISULA, Auteur ; Tracey SELLERS, Auteur ; Manuel POSADA DE LA PAZ, Auteur . - p.3380-3394. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-9 (September 2020) . - p.3380-3394 Mots-clés : Autism spectrum disorder  Diagnosis  Early detection  Mental health services  Patient satisfaction  Survey Index. décimale : PER Périodiques Résumé : Early services for ASD need to canvas the opinions of both parents and professionals. These opinions are seldom compared in the same research study. This study aims to ascertain the views of families and professionals on early detection, diagnosis and intervention services for young children with ASD. An online survey compiled and analysed data from 2032 respondents across 14 European countries (60.9% were parents; 39.1% professionals). Using an ordinal scale from 1 to 7, parents' opinions were more negative (mean?=?4.6; SD 2.2) compared to those of professionals (mean?=?4.9; SD 1.5) when reporting satisfaction with services. The results suggest services should take into account child's age, delays in accessing services, and active stakeholders' participation when looking to improve services. En ligne : http://dx.doi.org/10.1007/s10803-019-04253-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=430

Feedback-Driven Learning Through Eye Movements in Autism Spectrum Disorder / David SALDANA ; Mila VULCHANOVA ; Maria Luisa SCATTONI ; Martina MICAI in Autism Research, 18-7 (July 2025)  

Public ISBD [article]  inAutism Research > 18-7 (July 2025) . - p.1431-1446 Titre : Feedback-Driven Learning Through Eye Movements in Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : David SALDANA, Auteur ; Mila VULCHANOVA, Auteur ; Maria Luisa SCATTONI, Auteur ; Martina MICAI, Auteur Article en page(s) : p.1431-1446 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  executive function  eye movements  feedback  neuropsychological tests Index. décimale : PER Périodiques Résumé : ABSTRACT Individuals with Autism Spectrum Disorder (ASD) face challenges in cognitive flexibility and rule-shifting. This study investigated a computerized Wisconsin Card Sorting Task (WCST) paired with eye-tracking to understand the cognitive dynamics of set-shifting difficulties in autistic children and adolescents. The study included 21 Spanish-speaking autistic children and adolescents (mean age: 14.5?years) and 22 typically developing peers (mean age: 15.1), matched by gender, age, language, working memory, and intelligence. Participants sorted cards by number, color, or shape, receiving feedback after each trial. The sorting criterion changed after 10 correct responses without participants' prior knowledge. The task included 128 trials, followed by three strategy-related verbal questions. Behavioral and eye movement data showed that the autistic group performed worse, completing fewer sets and making more errors. Both groups had increased fixations and dwell time after feedback, but controls had a greater increase after incorrect responses. Autistic individuals may struggle with error monitoring and response inhibition, impacting their adaptability and less efficient learning of sorting rules. They engaged less in error analysis and correction than controls. Targeted interventions to enhance feedback processing and adaptive learning strategies could benefit autistic individuals. Future research should explore mechanisms behind eye-movement differences and the effectiveness of related interventions. En ligne : https://doi.org/10.1002/aur.70060 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=565 [article] Feedback-Driven Learning Through Eye Movements in Autism Spectrum Disorder [Texte imprimé et/ou numérique] / David SALDANA, Auteur ; Mila VULCHANOVA, Auteur ; Maria Luisa SCATTONI, Auteur ; Martina MICAI, Auteur . - p.1431-1446. Langues : Anglais (eng) in Autism Research > 18-7 (July 2025) . - p.1431-1446 Mots-clés : autism spectrum disorder  executive function  eye movements  feedback  neuropsychological tests Index. décimale : PER Périodiques Résumé : ABSTRACT Individuals with Autism Spectrum Disorder (ASD) face challenges in cognitive flexibility and rule-shifting. This study investigated a computerized Wisconsin Card Sorting Task (WCST) paired with eye-tracking to understand the cognitive dynamics of set-shifting difficulties in autistic children and adolescents. The study included 21 Spanish-speaking autistic children and adolescents (mean age: 14.5?years) and 22 typically developing peers (mean age: 15.1), matched by gender, age, language, working memory, and intelligence. Participants sorted cards by number, color, or shape, receiving feedback after each trial. The sorting criterion changed after 10 correct responses without participants' prior knowledge. The task included 128 trials, followed by three strategy-related verbal questions. Behavioral and eye movement data showed that the autistic group performed worse, completing fewer sets and making more errors. Both groups had increased fixations and dwell time after feedback, but controls had a greater increase after incorrect responses. Autistic individuals may struggle with error monitoring and response inhibition, impacting their adaptability and less efficient learning of sorting rules. They engaged less in error analysis and correction than controls. Targeted interventions to enhance feedback processing and adaptive learning strategies could benefit autistic individuals. Future research should explore mechanisms behind eye-movement differences and the effectiveness of related interventions. En ligne : https://doi.org/10.1002/aur.70060 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=565

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication / Ozlem BOZDAGI in Molecular Autism, (December 2010)  

Public ISBD [article]  inMolecular Autism > (December 2010) . - 47 p. Titre : Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication Type de document : Texte imprimé et/ou numérique Auteurs : Ozlem BOZDAGI, Auteur ; Takeshi SAKURAI, Auteur ; Danae PAPAPETROU, Auteur ; Xiaobin WANG, Auteur ; Dara L. DICKSTEIN, Auteur ; Nagahide TAKAHASHI, Auteur ; Yuji KAJIWARA, Auteur ; Mu YANG, Auteur ; Adam M. KATZ, Auteur ; Maria Luisa SCATTONI, Auteur ; Mark J. HARRIS, Auteur ; Roheeni SAXENA, Auteur ; Jill L. SILVERMAN, Auteur ; Jacqueline N. CRAWLEY, Auteur ; Qiang ZHOU, Auteur ; Patrick R. HOF, Auteur ; Joseph D. BUXBAUM, Auteur Année de publication : 2010 Article en page(s) : 47 p. Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : SHANK3 is a protein in the core of the postsynaptic density (PSD) and has a critical role in recruiting many key functional elements to the PSD and to the synapse, including components of alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionic acid (AMPA), metabotropic glutamate (mGlu) and N-methyl-D-aspartic acid (NMDA) glutamate receptors, as well as cytoskeletal elements. Loss of a functional copy of the SHANK3 gene leads to the neurobehavioral manifestations of 22q13 deletion syndrome and/or to autism spectrum disorders. The goal of this study was to examine the effects of haploinsufficiency of full-length Shank3 in mice, focusing on synaptic development, transmission and plasticity, as well as on social behaviors, as a model for understanding SHANK3 haploinsufficiency in humans. Methods We used mice with a targeted disruption of Shank3 in which exons coding for the ankyrin repeat domain were deleted and expression of full-length Shank3 was disrupted. We studied synaptic transmission and plasticity by multiple methods, including patch-clamp whole cell recording, two-photon time-lapse imaging and extracellular recordings of field excitatory postsynaptic potentials. We also studied the density of GluR1-immunoreactive puncta in the CA1 stratum radiatum and carried out assessments of social behaviors. Results In Shank3 heterozygous mice, there was reduced amplitude of miniature excitatory postsynaptic currents from hippocampal CA1 pyramidal neurons and the input-output (I/O) relationship at Schaffer collateral-CA1 synapses in acute hippocampal slices was significantly depressed; both of these findings indicate a reduction in basal neurotransmission. Studies with specific inhibitors demonstrated that the decrease in basal transmission reflected reduced AMPA receptor-mediated transmission. This was further supported by the observation of reduced numbers of GluR1-immunoreactive puncta in the stratum radiatum. Long-term potentiation (LTP), induced either with theta-burst pairing (TBP) or high-frequency stimulation, was impaired in Shank3 heterozygous mice, with no significant change in long-term depression (LTD). In concordance with the LTP results, persistent expansion of spines was observed in control mice after TBP-induced LTP; however, only transient spine expansion was observed in Shank3 heterozygous mice. Male Shank3 heterozygotes displayed less social sniffing and emitted fewer ultrasonic vocalizations during interactions with estrus female mice, as compared to wild-type littermate controls. Conclusions We documented specific deficits in synaptic function and plasticity, along with reduced reciprocal social interactions in Shank3 heterozygous mice. Our results are consistent with altered synaptic development and function in Shank3 haploinsufficiency, highlighting the importance of Shank3 in synaptic function and supporting a link between deficits in synapse function and neurodevelopmental disorders. The reduced glutamatergic transmission that we observed in the Shank3 heterozygous mice represents an interesting therapeutic target in Shank3-haploinsufficiency syndromes. En ligne : http://dx.doi.org/10.1186/2040-2392-1-15 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=114 [article] Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication [Texte imprimé et/ou numérique] / Ozlem BOZDAGI, Auteur ; Takeshi SAKURAI, Auteur ; Danae PAPAPETROU, Auteur ; Xiaobin WANG, Auteur ; Dara L. DICKSTEIN, Auteur ; Nagahide TAKAHASHI, Auteur ; Yuji KAJIWARA, Auteur ; Mu YANG, Auteur ; Adam M. KATZ, Auteur ; Maria Luisa SCATTONI, Auteur ; Mark J. HARRIS, Auteur ; Roheeni SAXENA, Auteur ; Jill L. SILVERMAN, Auteur ; Jacqueline N. CRAWLEY, Auteur ; Qiang ZHOU, Auteur ; Patrick R. HOF, Auteur ; Joseph D. BUXBAUM, Auteur . - 2010 . - 47 p. Langues : Anglais (eng) in Molecular Autism > (December 2010) . - 47 p. Index. décimale : PER Périodiques Résumé : SHANK3 is a protein in the core of the postsynaptic density (PSD) and has a critical role in recruiting many key functional elements to the PSD and to the synapse, including components of alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionic acid (AMPA), metabotropic glutamate (mGlu) and N-methyl-D-aspartic acid (NMDA) glutamate receptors, as well as cytoskeletal elements. Loss of a functional copy of the SHANK3 gene leads to the neurobehavioral manifestations of 22q13 deletion syndrome and/or to autism spectrum disorders. The goal of this study was to examine the effects of haploinsufficiency of full-length Shank3 in mice, focusing on synaptic development, transmission and plasticity, as well as on social behaviors, as a model for understanding SHANK3 haploinsufficiency in humans. Methods We used mice with a targeted disruption of Shank3 in which exons coding for the ankyrin repeat domain were deleted and expression of full-length Shank3 was disrupted. We studied synaptic transmission and plasticity by multiple methods, including patch-clamp whole cell recording, two-photon time-lapse imaging and extracellular recordings of field excitatory postsynaptic potentials. We also studied the density of GluR1-immunoreactive puncta in the CA1 stratum radiatum and carried out assessments of social behaviors. Results In Shank3 heterozygous mice, there was reduced amplitude of miniature excitatory postsynaptic currents from hippocampal CA1 pyramidal neurons and the input-output (I/O) relationship at Schaffer collateral-CA1 synapses in acute hippocampal slices was significantly depressed; both of these findings indicate a reduction in basal neurotransmission. Studies with specific inhibitors demonstrated that the decrease in basal transmission reflected reduced AMPA receptor-mediated transmission. This was further supported by the observation of reduced numbers of GluR1-immunoreactive puncta in the stratum radiatum. Long-term potentiation (LTP), induced either with theta-burst pairing (TBP) or high-frequency stimulation, was impaired in Shank3 heterozygous mice, with no significant change in long-term depression (LTD). In concordance with the LTP results, persistent expansion of spines was observed in control mice after TBP-induced LTP; however, only transient spine expansion was observed in Shank3 heterozygous mice. Male Shank3 heterozygotes displayed less social sniffing and emitted fewer ultrasonic vocalizations during interactions with estrus female mice, as compared to wild-type littermate controls. Conclusions We documented specific deficits in synaptic function and plasticity, along with reduced reciprocal social interactions in Shank3 heterozygous mice. Our results are consistent with altered synaptic development and function in Shank3 haploinsufficiency, highlighting the importance of Shank3 in synaptic function and supporting a link between deficits in synapse function and neurodevelopmental disorders. The reduced glutamatergic transmission that we observed in the Shank3 heterozygous mice represents an interesting therapeutic target in Shank3-haploinsufficiency syndromes. En ligne : http://dx.doi.org/10.1186/2040-2392-1-15 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=114

Intervention Services for Autistic Adults: An ASDEU Study of Autistic Adults, Carers, and Professionals' Experiences / Martina MICAI in Journal of Autism and Developmental Disorders, 52-4 (April 2022)  

Permalink

Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice / Kathryn K. CHADMAN in Autism Research, 1-3 (June 2008)  

Permalink

Modeling Social Communication Deficits in Mouse Models of Autism / Caterina MICHETTI in Autism - Open Access, 2-S ([01/12/2012])  

Permalink

Mouse Behavior and Models for Autism Spectrum Disorders / Laura RICCERI  

Permalink

Program for the Education and Enrichment of Relational Skills (PEERS®) for Italy: A Randomized Controlled Trial of a Social Skills Intervention for Autistic Adolescents / Laura Maria FATTA ; Elizabeth A. LAUGESON ; Dora Bianchi ; Fiorenzo LAGHI ; Maria Luisa SCATTONI ; group Italian Peers® team support in Journal of Autism and Developmental Disorders, 55-1 (January 2025)  

Permalink

Supporting Caregivers Remotely During a Pandemic: Comparison of WHO Caregiver Skills Training Delivered Online Versus in Person in Public Health Settings in Italy / Paola SORGATO ; Mariachiara FIORAVANTI ; Laura PACIONE ; Giuseppe Maurizio ARDUINO ; Sabrina GHERSI ; Maria Luisa SCATTONI ; Camilla CHIESA ; Donatella ELIA ; Elisabetta GONELLA ; Sara RIZZO ; Arianna SALANDIN ; Felicity L. BROWN ; Stephanie Shire ; Chiara SERVILI ; Erica SALOMONE ; C. S. T. Italy TEAM ; WHO CST TEAM in Journal of Autism and Developmental Disorders, 54-2 (February 2024)  

Permalink

The teleNIDA: Early Screening of Autism Spectrum Disorder Through a Novel Telehealth Approach / Valentina RIVA in Journal of Autism and Developmental Disorders, 54-5 (May 2024)  

Permalink

---

1 (1 - 12 / 12)