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19-2 - February 2026 [texte imprimé] . - 2026. Langues : Anglais (eng)
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Dépouillements
Ajouter le résultat dans votre panierExploring Alexithymia, Uncertainty, Anxious Arousal, and Social Anxiety as Mediators of the Relationship Between Sensory Processing Differences and Restricted and Repetitive Behaviors in Autistic Adults / Heather L. MOORE in Autism Research, 19-2 (February 2026)
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Titre : Exploring Alexithymia, Uncertainty, Anxious Arousal, and Social Anxiety as Mediators of the Relationship Between Sensory Processing Differences and Restricted and Repetitive Behaviors in Autistic Adults Type de document : texte imprimé Auteurs : Heather L. MOORE, Auteur ; Samuel BRICE, Auteur ; Natalya SPRAGGON, Auteur ; Barry INGHAM, Auteur ; Mark FREESTON, Auteur ; Jeremy R. PARR, Auteur ; Jacqui RODGERS, Auteur Article en page(s) : e70145 Langues : Anglais (eng) Mots-clés : alexithymia anxious arousal autism restricted and repetitive behaviors sensory processing social anxiety uncertainty Index. décimale : PER Périodiques Résumé : ABSTRACT Restricted and repetitive behaviors (RRB) are associated with sensory processing (SP) differences for autistic people, and are thought to be a coping strategy to help manage the sensory environment. Previous work shows that, for autistic people, alexithymia, intolerance of uncertainty (IU), and anxiety mediate the relationship between SP differences and RRB. However, these studies use anxiety measures developed for the general population, and more recent evidence suggests that autistic people may have a different anxiety experience. This study aims to extend previous findings by unpacking the anxiety experience for autistic adults in the relationship between SP differences and RRB, using an autism-specific anxiety measure. Data were available from 426 autistic adults. Serial mediation models tested the relationship between SP differences and RRB, with alexithymia, IU, anxious arousal, and social anxiety as mediators. We identified significant direct effects from SP differences to both repetitive motor behaviors (RMB) and insistence on sameness behaviors (ISB). For RMB, we found indirect effects through anxious arousal, alexithymia-anxious arousal, IU-anxious arousal, and alexithymia-IU-anxious arousal. For ISB, we found indirect effects through IU and alexithymia-IU. Thus, different mechanisms may underpin RMB and ISB. Understanding the anxiety experience of autistic people, alongside the role of SP and RRB, is key to providing tailored support, adjustments, and psychological interventions to autistic people. Future research could benefit from directly investigating the impact of strategies to support SP and anxiety. En ligne : https://doi.org/10.1002/aur.70145 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70145[article] Exploring Alexithymia, Uncertainty, Anxious Arousal, and Social Anxiety as Mediators of the Relationship Between Sensory Processing Differences and Restricted and Repetitive Behaviors in Autistic Adults [texte imprimé] / Heather L. MOORE, Auteur ; Samuel BRICE, Auteur ; Natalya SPRAGGON, Auteur ; Barry INGHAM, Auteur ; Mark FREESTON, Auteur ; Jeremy R. PARR, Auteur ; Jacqui RODGERS, Auteur . - e70145.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70145
Mots-clés : alexithymia anxious arousal autism restricted and repetitive behaviors sensory processing social anxiety uncertainty Index. décimale : PER Périodiques Résumé : ABSTRACT Restricted and repetitive behaviors (RRB) are associated with sensory processing (SP) differences for autistic people, and are thought to be a coping strategy to help manage the sensory environment. Previous work shows that, for autistic people, alexithymia, intolerance of uncertainty (IU), and anxiety mediate the relationship between SP differences and RRB. However, these studies use anxiety measures developed for the general population, and more recent evidence suggests that autistic people may have a different anxiety experience. This study aims to extend previous findings by unpacking the anxiety experience for autistic adults in the relationship between SP differences and RRB, using an autism-specific anxiety measure. Data were available from 426 autistic adults. Serial mediation models tested the relationship between SP differences and RRB, with alexithymia, IU, anxious arousal, and social anxiety as mediators. We identified significant direct effects from SP differences to both repetitive motor behaviors (RMB) and insistence on sameness behaviors (ISB). For RMB, we found indirect effects through anxious arousal, alexithymia-anxious arousal, IU-anxious arousal, and alexithymia-IU-anxious arousal. For ISB, we found indirect effects through IU and alexithymia-IU. Thus, different mechanisms may underpin RMB and ISB. Understanding the anxiety experience of autistic people, alongside the role of SP and RRB, is key to providing tailored support, adjustments, and psychological interventions to autistic people. Future research could benefit from directly investigating the impact of strategies to support SP and anxiety. En ligne : https://doi.org/10.1002/aur.70145 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 Anomalous Pattern of Left Hemisphere Visual Connectivity in Children With Autism: Association With Impaired Praxis / Jonah MCLAUGHLIN in Autism Research, 19-2 (February 2026)
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Titre : Anomalous Pattern of Left Hemisphere Visual Connectivity in Children With Autism: Association With Impaired Praxis Type de document : texte imprimé Auteurs : Jonah MCLAUGHLIN, Auteur ; Deana CROCETTI, Auteur ; Stewart H. MOSTOFSKY, Auteur ; Daniel E. LIDSTONE, Auteur Article en page(s) : e70146 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : ABSTRACT Prominent theories of autism suggest autism-associated differences in visual-motor integration (VMI) may disrupt learning of motor and social skills typically acquired by observation and imitation. Supporting these theories, children with autism spectrum disorder (ASD) show robust differences in motor tasks reliant on dynamic VMI (e.g., ball-catching and motor imitation) and anomalous visual-motor connectivity between higher-order visual (HOV) and sensory-motor cortices. Use of functional MRI (fMRI) to examine HOV functional connectivity (FC) has been particularly revealing with other conditions. For instance, research with congenitally blind adults reveals a particular pattern of altered HOV connectivity, showing reduced HOV connectivity with primary sensory-motor (SM1) and primary auditory (A1) cortices yet ?compensatory? increased connectivity between HOV and prefrontal cortex (PFC). Informed by these findings, we used fMRI to examine HOV FC in children with ASD, hypothesizing they would show a distinct pattern of HOV connectivity relative to typically developing (TD) children, with decreased HOV-SM1 connectivity and increased ?compensatory? HOV-PFC connectivity. We further hypothesized that this altered pattern of HOV connectivity would correlate with autism-associated difficulties with performing skilled actions (?praxis?), often learned through visual imitation. Our findings suggest ASD children show an altered pattern of HOV connectivity that is characterized by reduced HOV connectivity with SM1 yet increased connectivity with PFC. Further, this HOV connectivity correlated with impaired praxis in children with ASD, suggesting that altered patterns of HOV connectivity may contribute to difficulty acquiring a range of skilled behaviors observed in autism. En ligne : https://doi.org/10.1002/aur.70146 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70146[article] Anomalous Pattern of Left Hemisphere Visual Connectivity in Children With Autism: Association With Impaired Praxis [texte imprimé] / Jonah MCLAUGHLIN, Auteur ; Deana CROCETTI, Auteur ; Stewart H. MOSTOFSKY, Auteur ; Daniel E. LIDSTONE, Auteur . - e70146.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70146
Index. décimale : PER Périodiques Résumé : ABSTRACT Prominent theories of autism suggest autism-associated differences in visual-motor integration (VMI) may disrupt learning of motor and social skills typically acquired by observation and imitation. Supporting these theories, children with autism spectrum disorder (ASD) show robust differences in motor tasks reliant on dynamic VMI (e.g., ball-catching and motor imitation) and anomalous visual-motor connectivity between higher-order visual (HOV) and sensory-motor cortices. Use of functional MRI (fMRI) to examine HOV functional connectivity (FC) has been particularly revealing with other conditions. For instance, research with congenitally blind adults reveals a particular pattern of altered HOV connectivity, showing reduced HOV connectivity with primary sensory-motor (SM1) and primary auditory (A1) cortices yet ?compensatory? increased connectivity between HOV and prefrontal cortex (PFC). Informed by these findings, we used fMRI to examine HOV FC in children with ASD, hypothesizing they would show a distinct pattern of HOV connectivity relative to typically developing (TD) children, with decreased HOV-SM1 connectivity and increased ?compensatory? HOV-PFC connectivity. We further hypothesized that this altered pattern of HOV connectivity would correlate with autism-associated difficulties with performing skilled actions (?praxis?), often learned through visual imitation. Our findings suggest ASD children show an altered pattern of HOV connectivity that is characterized by reduced HOV connectivity with SM1 yet increased connectivity with PFC. Further, this HOV connectivity correlated with impaired praxis in children with ASD, suggesting that altered patterns of HOV connectivity may contribute to difficulty acquiring a range of skilled behaviors observed in autism. En ligne : https://doi.org/10.1002/aur.70146 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 Prevalence of OSA Risk and Bruxism in Children With Autism Spectrum Disorders / Anna ALESSANDRI-BONETTI in Autism Research, 19-2 (February 2026)
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Titre : Prevalence of OSA Risk and Bruxism in Children With Autism Spectrum Disorders Type de document : texte imprimé Auteurs : Anna ALESSANDRI-BONETTI, Auteur ; Federica GUGLIELMI, Auteur ; Andrea FAUSTINI, Auteur ; Linda SANGALLI, Auteur ; Edoardo STADERINI, Auteur ; Patrizia GALLENZI, Auteur Article en page(s) : e70149 Langues : Anglais (eng) Mots-clés : autism spectrum disorder awake bruxism obstructive sleep apnea sleep bruxism validated questionnaires Index. décimale : PER Périodiques Résumé : ABSTRACT Children with autism spectrum disorder (ASD) often present with sleep disorders, including obstructive sleep apnea (OSA), a condition characterized by upper airway obstruction during sleep. Bruxism has been recently described as being associated with OSA. This study aimed to assess the prevalence of OSA risk and bruxism in pediatric ASD patients compared to age and sex-matched healthy controls using the validated screening tool Sleep-Related Breathing Disorder scale of the Pediatric Sleep Questionnaire (SRBD-PSQ). Fifty-eight consecutive pediatric ASD patients were screened for OSA and bruxism at the Dentistry Unit of A. Gemelli Policlinic and compared to 58 healthy patients using chi-square tests. Comparison between the two groups was repeated by controlling for body mass index (BMI) and behavioral symptoms with ANCOVA and logistic regression analyses. Of 58 ASD patients (10.3?±?3.3 y/o, 74.5% males), 60.3% presented with an increased OSA risk, compared to 13.8% in the controls (p?0.001, OR?=?3.682, 95% CI: 1.933, 7.012). After controlling for BMI (which was significantly higher among ASD patients), those with ASD had significantly higher odds of OSA risk compared to controls (OR?=?9.6, 95% CI: 3.56, 26.21). After controlling for the SRBD-PSQ behavioral component, the association between ASD and OSA risk lost its significant difference (p?0.862). No significant difference was found between ASD patients and controls in awake (3.6% vs. 6.9%, p?=?0.680) and sleep (25.5% vs. 32.8%, p?=?0.393) bruxism. Pediatric patients with ASD present at higher risk of OSA, most likely explained by the behavioral symptoms; self-reported bruxism did not significantly differ compared to healthy controls. En ligne : https://doi.org/10.1002/aur.70149 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70149[article] Prevalence of OSA Risk and Bruxism in Children With Autism Spectrum Disorders [texte imprimé] / Anna ALESSANDRI-BONETTI, Auteur ; Federica GUGLIELMI, Auteur ; Andrea FAUSTINI, Auteur ; Linda SANGALLI, Auteur ; Edoardo STADERINI, Auteur ; Patrizia GALLENZI, Auteur . - e70149.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70149
Mots-clés : autism spectrum disorder awake bruxism obstructive sleep apnea sleep bruxism validated questionnaires Index. décimale : PER Périodiques Résumé : ABSTRACT Children with autism spectrum disorder (ASD) often present with sleep disorders, including obstructive sleep apnea (OSA), a condition characterized by upper airway obstruction during sleep. Bruxism has been recently described as being associated with OSA. This study aimed to assess the prevalence of OSA risk and bruxism in pediatric ASD patients compared to age and sex-matched healthy controls using the validated screening tool Sleep-Related Breathing Disorder scale of the Pediatric Sleep Questionnaire (SRBD-PSQ). Fifty-eight consecutive pediatric ASD patients were screened for OSA and bruxism at the Dentistry Unit of A. Gemelli Policlinic and compared to 58 healthy patients using chi-square tests. Comparison between the two groups was repeated by controlling for body mass index (BMI) and behavioral symptoms with ANCOVA and logistic regression analyses. Of 58 ASD patients (10.3?±?3.3 y/o, 74.5% males), 60.3% presented with an increased OSA risk, compared to 13.8% in the controls (p?0.001, OR?=?3.682, 95% CI: 1.933, 7.012). After controlling for BMI (which was significantly higher among ASD patients), those with ASD had significantly higher odds of OSA risk compared to controls (OR?=?9.6, 95% CI: 3.56, 26.21). After controlling for the SRBD-PSQ behavioral component, the association between ASD and OSA risk lost its significant difference (p?0.862). No significant difference was found between ASD patients and controls in awake (3.6% vs. 6.9%, p?=?0.680) and sleep (25.5% vs. 32.8%, p?=?0.393) bruxism. Pediatric patients with ASD present at higher risk of OSA, most likely explained by the behavioral symptoms; self-reported bruxism did not significantly differ compared to healthy controls. En ligne : https://doi.org/10.1002/aur.70149 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 Understanding Self-Compassion in Autistic Adults: Validity Evidence and Its Links to Loneliness and Depression Across Autistic and Non-Autistic Individuals / Ru Ying CAI in Autism Research, 19-2 (February 2026)
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Titre : Understanding Self-Compassion in Autistic Adults: Validity Evidence and Its Links to Loneliness and Depression Across Autistic and Non-Autistic Individuals Type de document : texte imprimé Auteurs : Ru Ying CAI, Auteur ; David M. DUEBER, Auteur ; Michael D. TOLAND, Auteur ; Vicki GIBBS, Auteur ; Chris EDWARDS, Auteur ; Abigail M. A. LOVE, Auteur Article en page(s) : e70150 Langues : Anglais (eng) Mots-clés : adults autism depression loneliness mental health moderation self-compassion Index. décimale : PER Périodiques Résumé : ABSTRACT Autistic adults face higher rates of loneliness and depression than non-autistic adults. Self-compassion may offer a protective buffer against mental health difficulties, but its measurement validity and interaction with loneliness have not been studied in autistic populations. This two-part study examined (1) the dimensional structure of the Self-Compassion Scale (SCS) in a global sample of autistic (n?=?377) and non-autistic (n?=?196) adults, and (2) whether self-compassion moderates the relationship between loneliness and depression in both groups. Confirmatory factor analyses tested multiple models of the SCS, and multigroup regression models tested moderation effects using loneliness and depression scores. The SCS was best represented by two factors?compassionate and uncompassionate self-responding?in both autistic and non-autistic groups. Measurement invariance was supported. In moderation analyses, uncompassionate self-responding significantly moderated the relationship between loneliness and depressive symptoms among non-autistic adults, but not autistic adults. Uncompassionate self-responding was significantly associated with greater depression symptoms in both groups. These findings support using a two-factor structure of the SCS in autistic samples and suggest that reducing uncompassionate self-responding may benefit mental health broadly. However, self-compassion did not buffer the loneliness?depression link for autistic adults, highlighting the need for alternative protective factors tailored to this population. En ligne : https://doi.org/10.1002/aur.70150 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70150[article] Understanding Self-Compassion in Autistic Adults: Validity Evidence and Its Links to Loneliness and Depression Across Autistic and Non-Autistic Individuals [texte imprimé] / Ru Ying CAI, Auteur ; David M. DUEBER, Auteur ; Michael D. TOLAND, Auteur ; Vicki GIBBS, Auteur ; Chris EDWARDS, Auteur ; Abigail M. A. LOVE, Auteur . - e70150.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70150
Mots-clés : adults autism depression loneliness mental health moderation self-compassion Index. décimale : PER Périodiques Résumé : ABSTRACT Autistic adults face higher rates of loneliness and depression than non-autistic adults. Self-compassion may offer a protective buffer against mental health difficulties, but its measurement validity and interaction with loneliness have not been studied in autistic populations. This two-part study examined (1) the dimensional structure of the Self-Compassion Scale (SCS) in a global sample of autistic (n?=?377) and non-autistic (n?=?196) adults, and (2) whether self-compassion moderates the relationship between loneliness and depression in both groups. Confirmatory factor analyses tested multiple models of the SCS, and multigroup regression models tested moderation effects using loneliness and depression scores. The SCS was best represented by two factors?compassionate and uncompassionate self-responding?in both autistic and non-autistic groups. Measurement invariance was supported. In moderation analyses, uncompassionate self-responding significantly moderated the relationship between loneliness and depressive symptoms among non-autistic adults, but not autistic adults. Uncompassionate self-responding was significantly associated with greater depression symptoms in both groups. These findings support using a two-factor structure of the SCS in autistic samples and suggest that reducing uncompassionate self-responding may benefit mental health broadly. However, self-compassion did not buffer the loneliness?depression link for autistic adults, highlighting the need for alternative protective factors tailored to this population. En ligne : https://doi.org/10.1002/aur.70150 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 Atypical Visually Guided Precision Grip Control in Middle-Aged and Older Autistic Adults / Zheng WANG in Autism Research, 19-2 (February 2026)
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Titre : Atypical Visually Guided Precision Grip Control in Middle-Aged and Older Autistic Adults Type de document : texte imprimé Auteurs : Zheng WANG, Auteur ; Hang QU, Auteur ; Danielle CHRISTENSEN, Auteur ; Hanna M. GEMMELL, Auteur ; Ellen M. PARKS, Auteur ; Kyla E. WETHERINGTON, Auteur ; Ann-Marie ORLANDO, Auteur ; Regilda A. ROMERO, Auteur ; Bikram KARMAKAR, Auteur ; David E. VAILLANCOURT, Auteur Article en page(s) : e70154 Langues : Anglais (eng) Mots-clés : aging autism spectrum disorder fine motor control middle-aged and older adults precision grip Index. décimale : PER Périodiques Résumé : ABSTRACT Sensorimotor impairments are well documented in autism spectrum disorder (ASD). However, little is known about how these difficulties present in middle-aged and older autistic adults or how they relate to demographic factors and autistic traits. In this study, 52 autistic and 56 age- and sex-matched non-autistic adults (aged 30?73?years) completed a visually guided precision grip task designed to assess temporal (reaction time, duration), spatial (force accuracy, variability), and dynamic (rate of force change) features of grip control under two conditions: varying motor output demands (target force test) and visual feedback (visual gain test). Autistic adults showed prolonged duration, delayed reaction time, and greater target overshooting at lower force levels during the rise phase. During the sustained phase, they exhibited increased grip force variability across both tasks. In contrast, autistic adults demonstrated shorter reaction times during the relaxation phase. Subgroup analyses revealed that the middle-aged autistic subgroup displayed elevated grip force variability, whereas the older autistic subgroup showed broader impairments affecting both spatial and temporal aspects of precision gripping. Within the autistic group, temporal grip force variables under the low target force condition were significantly associated with age and repetitive behaviors. These findings demonstrate that manual motor impairments persist into adulthood in ASD, and suggest shared neurobiological networks that underlie both motor dysfunction and core autistic traits. En ligne : https://doi.org/10.1002/aur.70154 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70154[article] Atypical Visually Guided Precision Grip Control in Middle-Aged and Older Autistic Adults [texte imprimé] / Zheng WANG, Auteur ; Hang QU, Auteur ; Danielle CHRISTENSEN, Auteur ; Hanna M. GEMMELL, Auteur ; Ellen M. PARKS, Auteur ; Kyla E. WETHERINGTON, Auteur ; Ann-Marie ORLANDO, Auteur ; Regilda A. ROMERO, Auteur ; Bikram KARMAKAR, Auteur ; David E. VAILLANCOURT, Auteur . - e70154.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70154
Mots-clés : aging autism spectrum disorder fine motor control middle-aged and older adults precision grip Index. décimale : PER Périodiques Résumé : ABSTRACT Sensorimotor impairments are well documented in autism spectrum disorder (ASD). However, little is known about how these difficulties present in middle-aged and older autistic adults or how they relate to demographic factors and autistic traits. In this study, 52 autistic and 56 age- and sex-matched non-autistic adults (aged 30?73?years) completed a visually guided precision grip task designed to assess temporal (reaction time, duration), spatial (force accuracy, variability), and dynamic (rate of force change) features of grip control under two conditions: varying motor output demands (target force test) and visual feedback (visual gain test). Autistic adults showed prolonged duration, delayed reaction time, and greater target overshooting at lower force levels during the rise phase. During the sustained phase, they exhibited increased grip force variability across both tasks. In contrast, autistic adults demonstrated shorter reaction times during the relaxation phase. Subgroup analyses revealed that the middle-aged autistic subgroup displayed elevated grip force variability, whereas the older autistic subgroup showed broader impairments affecting both spatial and temporal aspects of precision gripping. Within the autistic group, temporal grip force variables under the low target force condition were significantly associated with age and repetitive behaviors. These findings demonstrate that manual motor impairments persist into adulthood in ASD, and suggest shared neurobiological networks that underlie both motor dysfunction and core autistic traits. En ligne : https://doi.org/10.1002/aur.70154 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 An Examination of Racial Bias in Scoring the Autism Diagnostic Observation Schedule (ADOS) Module 3: An Item Response Theory Analysis / Yuen Yvonne YU in Autism Research, 19-2 (February 2026)
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Titre : An Examination of Racial Bias in Scoring the Autism Diagnostic Observation Schedule (ADOS) Module 3: An Item Response Theory Analysis Type de document : texte imprimé Auteurs : Yuen Yvonne YU, Auteur ; Austin WYMAN, Auteur ; Calliana J. FAULK, Auteur ; Lizzy J. FULOP, Auteur ; Rebecca L. GREENBERG, Auteur ; Rachel M. BENECKE, Auteur ; Lauren K. STEINBECK, Auteur ; Jessica FOY, Auteur ; Caitlyn KIM, Auteur ; George O. EMORY, Auteur ; Eric A. STORCH, Auteur ; Casey J. ZAMPELLA, Auteur ; Benjamin E. YERYS, Auteur ; Robert T. SCHULTZ, Auteur ; Julia PARISH-MORRIS, Auteur ; John D. HERRINGTON, Auteur ; Caitlin C. CLEMENTS, Auteur Article en page(s) : e70155 Langues : Anglais (eng) Mots-clés : ADOS autism differential item functioning item response theory racial bias Index. décimale : PER Périodiques Résumé : ABSTRACT Given the rising prevalence of autism among racial minority children in the United States, but persistent service use disparities, this study examines potential bias in specific items from the autism diagnostic observation schedule (ADOS), a highly regarded autism evaluation. We leveraged unidimensional item response theory graded response models and a sample of 735 children to analyze the differential item functioning (DIF) of items within ADOS Module 3. Three items showed significant signs of racial bias: A1 (overall language level), A5 (offers information), and D5 (compulsions and rituals). On these items, Black/African American and Asian children were usually more likely to be rated as showing autistic behaviors than White children with similar autism levels. The impact of racial bias on the item score was small, and the impact on the overall test score was even smaller: on a scale of 0?48 points, the effect of racial bias was estimated at 0.23 total points for Black/African American children and 0.16 points for Asian children. Furthermore, none of the items showing significant bias contribute to the autism classification algorithm. This analysis suggests a small but detectable amount of bias in several specific ADOS items, but not in items central to informing an autism diagnosis. Thus, bias appears statistically, but not clinically, significant. This contributes to examinations of racial bias in the ADOS as the first analysis of Asian children and the first in-depth look at all items in the most commonly used version among school-aged children. En ligne : https://doi.org/10.1002/aur.70155 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70155[article] An Examination of Racial Bias in Scoring the Autism Diagnostic Observation Schedule (ADOS) Module 3: An Item Response Theory Analysis [texte imprimé] / Yuen Yvonne YU, Auteur ; Austin WYMAN, Auteur ; Calliana J. FAULK, Auteur ; Lizzy J. FULOP, Auteur ; Rebecca L. GREENBERG, Auteur ; Rachel M. BENECKE, Auteur ; Lauren K. STEINBECK, Auteur ; Jessica FOY, Auteur ; Caitlyn KIM, Auteur ; George O. EMORY, Auteur ; Eric A. STORCH, Auteur ; Casey J. ZAMPELLA, Auteur ; Benjamin E. YERYS, Auteur ; Robert T. SCHULTZ, Auteur ; Julia PARISH-MORRIS, Auteur ; John D. HERRINGTON, Auteur ; Caitlin C. CLEMENTS, Auteur . - e70155.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70155
Mots-clés : ADOS autism differential item functioning item response theory racial bias Index. décimale : PER Périodiques Résumé : ABSTRACT Given the rising prevalence of autism among racial minority children in the United States, but persistent service use disparities, this study examines potential bias in specific items from the autism diagnostic observation schedule (ADOS), a highly regarded autism evaluation. We leveraged unidimensional item response theory graded response models and a sample of 735 children to analyze the differential item functioning (DIF) of items within ADOS Module 3. Three items showed significant signs of racial bias: A1 (overall language level), A5 (offers information), and D5 (compulsions and rituals). On these items, Black/African American and Asian children were usually more likely to be rated as showing autistic behaviors than White children with similar autism levels. The impact of racial bias on the item score was small, and the impact on the overall test score was even smaller: on a scale of 0?48 points, the effect of racial bias was estimated at 0.23 total points for Black/African American children and 0.16 points for Asian children. Furthermore, none of the items showing significant bias contribute to the autism classification algorithm. This analysis suggests a small but detectable amount of bias in several specific ADOS items, but not in items central to informing an autism diagnosis. Thus, bias appears statistically, but not clinically, significant. This contributes to examinations of racial bias in the ADOS as the first analysis of Asian children and the first in-depth look at all items in the most commonly used version among school-aged children. En ligne : https://doi.org/10.1002/aur.70155 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 Mismatching Expressions: Spatiotemporal and Kinematic Differences in Autistic and Non-Autistic Facial Expressions / Connor T. KEATING in Autism Research, 19-2 (February 2026)
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Titre : Mismatching Expressions: Spatiotemporal and Kinematic Differences in Autistic and Non-Autistic Facial Expressions Type de document : texte imprimé Auteurs : Connor T. KEATING, Auteur ; Sophie SOWDEN-CARVALHO, Auteur ; Holly O′DONOGHUE, Auteur ; Jennifer L. COOK, Auteur Article en page(s) : e70157 Langues : Anglais (eng) Mots-clés : alexithymia autism emotion facial expression social interaction Index. décimale : PER Périodiques Résumé : ABSTRACT Preliminary studies suggest there are differences in the facial expressions produced by autistic and non-autistic individuals. However, it is unclear what specifically is different, whether such differences remain after controlling for facial morphology and alexithymia, and whether production differences relate to perception differences. Therefore, we (1) comprehensively compared the spatiotemporal and kinematic properties of autistic and non-autistic expressions after controlling these factors, and (2) examined the contribution of production-related variables to emotion perception. We used facial motion capture to record 2448 cued and 2448 spoken expressions of anger, happiness, and sadness from autistic and matched non-autistic adults. Subsequently, we extracted the activation and jerkiness of numerous facial landmarks across time, generating over 265 million datapoints. Participants also completed an emotion recognition task. Autistic participants relied more on the mouth, and less on the eyebrows, to signal anger than their non-autistic peers. For happiness, autistic participants showed a less exaggerated smile that also did not ?reach the eyes.? For sadness, autistic participants tended to produce a downturned expression by raising their upper lip more than their non-autistic peers. Alexithymia predicted less differentiated angry and happy expressions. For non-autistic individuals, those who produced more precise spoken expressions had greater emotion recognition accuracy. No production-related factors contributed to autistic emotion recognition. This mismatch could explain why autistic people find it difficult to recognize non-autistic expressions, and vice versa; autistic and non-autistic faces may be essentially ?speaking a different language? when conveying emotion. En ligne : https://doi.org/10.1002/aur.70157 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70157[article] Mismatching Expressions: Spatiotemporal and Kinematic Differences in Autistic and Non-Autistic Facial Expressions [texte imprimé] / Connor T. KEATING, Auteur ; Sophie SOWDEN-CARVALHO, Auteur ; Holly O′DONOGHUE, Auteur ; Jennifer L. COOK, Auteur . - e70157.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70157
Mots-clés : alexithymia autism emotion facial expression social interaction Index. décimale : PER Périodiques Résumé : ABSTRACT Preliminary studies suggest there are differences in the facial expressions produced by autistic and non-autistic individuals. However, it is unclear what specifically is different, whether such differences remain after controlling for facial morphology and alexithymia, and whether production differences relate to perception differences. Therefore, we (1) comprehensively compared the spatiotemporal and kinematic properties of autistic and non-autistic expressions after controlling these factors, and (2) examined the contribution of production-related variables to emotion perception. We used facial motion capture to record 2448 cued and 2448 spoken expressions of anger, happiness, and sadness from autistic and matched non-autistic adults. Subsequently, we extracted the activation and jerkiness of numerous facial landmarks across time, generating over 265 million datapoints. Participants also completed an emotion recognition task. Autistic participants relied more on the mouth, and less on the eyebrows, to signal anger than their non-autistic peers. For happiness, autistic participants showed a less exaggerated smile that also did not ?reach the eyes.? For sadness, autistic participants tended to produce a downturned expression by raising their upper lip more than their non-autistic peers. Alexithymia predicted less differentiated angry and happy expressions. For non-autistic individuals, those who produced more precise spoken expressions had greater emotion recognition accuracy. No production-related factors contributed to autistic emotion recognition. This mismatch could explain why autistic people find it difficult to recognize non-autistic expressions, and vice versa; autistic and non-autistic faces may be essentially ?speaking a different language? when conveying emotion. En ligne : https://doi.org/10.1002/aur.70157 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 The Impact of Theory of Mind on Real-Time Social Interactions and Momentary Social Anxiety: A Comparison Between Young Autistic and Neurotypical Children / Yu-Wei Ryan CHEN in Autism Research, 19-2 (February 2026)
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Titre : The Impact of Theory of Mind on Real-Time Social Interactions and Momentary Social Anxiety: A Comparison Between Young Autistic and Neurotypical Children Type de document : texte imprimé Auteurs : Yu-Wei Ryan CHEN, Auteur ; Sarah WILKES-GILLAN, Auteur ; Kuan-Lin CHEN, Auteur Article en page(s) : e70158 Langues : Anglais (eng) Mots-clés : autism neurotypical preschool children real-life social experience social anxiety theory of mind Index. décimale : PER Périodiques Résumé : ABSTRACT There is a growing need to examine how Theory of Mind (ToM) abilities impact real-time social engagement in autistic children. Caregivers of 45 young autistic children (70.7?±?23.3?months) and those of 36 neurotypical peers (59.2?±?11.8?months) carried a mobile device for 7?days to repeatedly record their child's social interactions and in-the-moment anxiety. They also completed the Social Responsiveness Scale-2 and the Theory of Mind Inventory-2 to evaluate their child's severity of autistic symptoms and ToM abilities. Multilevel analyses found that young autistic children with higher ToM abilities were more likely than those with lower abilities to interact with peers (OR?=?1.12, 95% CI?=?1.01?1.23) but also experienced more anxiety during interactions with both peers and adults (OR?=?1.36, 1.28, 95% CI?=?1.12?1.67, 1.01?1.63). In contrast, no significant associations between ToM and social interactions or anxiety were found in the neurotypical group. This study highlights the critical role of ToM abilities in the real-life social engagement of autistic children and emphasizes the importance of understanding real-time subjective social experiences. En ligne : https://doi.org/10.1002/aur.70158 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70158[article] The Impact of Theory of Mind on Real-Time Social Interactions and Momentary Social Anxiety: A Comparison Between Young Autistic and Neurotypical Children [texte imprimé] / Yu-Wei Ryan CHEN, Auteur ; Sarah WILKES-GILLAN, Auteur ; Kuan-Lin CHEN, Auteur . - e70158.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70158
Mots-clés : autism neurotypical preschool children real-life social experience social anxiety theory of mind Index. décimale : PER Périodiques Résumé : ABSTRACT There is a growing need to examine how Theory of Mind (ToM) abilities impact real-time social engagement in autistic children. Caregivers of 45 young autistic children (70.7?±?23.3?months) and those of 36 neurotypical peers (59.2?±?11.8?months) carried a mobile device for 7?days to repeatedly record their child's social interactions and in-the-moment anxiety. They also completed the Social Responsiveness Scale-2 and the Theory of Mind Inventory-2 to evaluate their child's severity of autistic symptoms and ToM abilities. Multilevel analyses found that young autistic children with higher ToM abilities were more likely than those with lower abilities to interact with peers (OR?=?1.12, 95% CI?=?1.01?1.23) but also experienced more anxiety during interactions with both peers and adults (OR?=?1.36, 1.28, 95% CI?=?1.12?1.67, 1.01?1.63). In contrast, no significant associations between ToM and social interactions or anxiety were found in the neurotypical group. This study highlights the critical role of ToM abilities in the real-life social engagement of autistic children and emphasizes the importance of understanding real-time subjective social experiences. En ligne : https://doi.org/10.1002/aur.70158 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 Effects of Cannabidiol on Social Relating, Anxiety, and Parental Stress in Autistic Children: A Randomized Controlled Crossover Trial / Nina-Francesca PARRELLA in Autism Research, 19-2 (February 2026)
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Titre : Effects of Cannabidiol on Social Relating, Anxiety, and Parental Stress in Autistic Children: A Randomized Controlled Crossover Trial Type de document : texte imprimé Auteurs : Nina-Francesca PARRELLA, Auteur ; Aron T. HILL, Auteur ; Peter G. ENTICOTT, Auteur ; Tanita BOTHA, Auteur ; Sarah CATCHLOVE, Auteur ; Luke DOWNEY, Auteur ; Talitha C. FORD, Auteur Article en page(s) : e70159 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : ABSTRACT Cannabidiol (CBD), a non-intoxicating compound derived from the cannabis plant, has garnered increasing attention as a potential pharmacological therapeutic for autism. We conducted a randomized, double-blind, placebo-controlled, crossover trial to understand whether oral CBD oil containing terpenes can improve outcomes in autistic children. Twenty-nine children (18 male), aged 5 to 12?years (M?=?9.62?years, SD?=?2.05), diagnosed with autism spectrum disorder, completed the study. Participants received weight-based dosing of CBD oil (10?mg/kg/day) or matched placebo oil over two 12-week intervention periods (crossover), separated by an 8-week washout period. Outcome measures included the Social Responsiveness Scale-2 (SRS-2; primary outcome), PROMIS Social Relating, Anxiety, and Sleep, Developmental Behavior Checklist-2 (DBC-2), Vineland-3, and Autism Parenting Stress Index (APSI; secondary outcomes). There was no significant effect observed for the primary outcome measure (SRS-2) for CBD oil relative to placebo oil after 12?weeks (??=??11.15, SE?=?7.19, p?=?0.125). Significant improvements were observed in secondary measures of social functioning, including DBC-2 Social Relating (??=??2.35, SE?=?0.92, p(adj)?=?0.024), as well as reduced anxiety on the DBC-2 subscale (??=??3.20, SE?=?0.94, p(adj)?=?0.002), and lower parental stress (APSI; ??=??4.63, SE?=?2.26, p(adj)?=?0.044). No differences were detected on Vineland-3 adaptive functioning (ABC: ??=?2.06, SE?=?2.67, p(adj)?=?1.000), and domain scores were not significant. Safety and tolerability data indicated that two children experienced gastrointestinal discomfort while taking CBD. Findings from this pilot trial suggest that while CBD combined with terpenes did not improve the primary outcome of social responsiveness, it may hold potential in addressing certain autism-related difficulties, particularly anxiety and social relating. Further research with larger sample sizes is needed to fully evaluate the efficacy and safety of CBD for autistic children. En ligne : https://doi.org/10.1002/aur.70159 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70159[article] Effects of Cannabidiol on Social Relating, Anxiety, and Parental Stress in Autistic Children: A Randomized Controlled Crossover Trial [texte imprimé] / Nina-Francesca PARRELLA, Auteur ; Aron T. HILL, Auteur ; Peter G. ENTICOTT, Auteur ; Tanita BOTHA, Auteur ; Sarah CATCHLOVE, Auteur ; Luke DOWNEY, Auteur ; Talitha C. FORD, Auteur . - e70159.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70159
Index. décimale : PER Périodiques Résumé : ABSTRACT Cannabidiol (CBD), a non-intoxicating compound derived from the cannabis plant, has garnered increasing attention as a potential pharmacological therapeutic for autism. We conducted a randomized, double-blind, placebo-controlled, crossover trial to understand whether oral CBD oil containing terpenes can improve outcomes in autistic children. Twenty-nine children (18 male), aged 5 to 12?years (M?=?9.62?years, SD?=?2.05), diagnosed with autism spectrum disorder, completed the study. Participants received weight-based dosing of CBD oil (10?mg/kg/day) or matched placebo oil over two 12-week intervention periods (crossover), separated by an 8-week washout period. Outcome measures included the Social Responsiveness Scale-2 (SRS-2; primary outcome), PROMIS Social Relating, Anxiety, and Sleep, Developmental Behavior Checklist-2 (DBC-2), Vineland-3, and Autism Parenting Stress Index (APSI; secondary outcomes). There was no significant effect observed for the primary outcome measure (SRS-2) for CBD oil relative to placebo oil after 12?weeks (??=??11.15, SE?=?7.19, p?=?0.125). Significant improvements were observed in secondary measures of social functioning, including DBC-2 Social Relating (??=??2.35, SE?=?0.92, p(adj)?=?0.024), as well as reduced anxiety on the DBC-2 subscale (??=??3.20, SE?=?0.94, p(adj)?=?0.002), and lower parental stress (APSI; ??=??4.63, SE?=?2.26, p(adj)?=?0.044). No differences were detected on Vineland-3 adaptive functioning (ABC: ??=?2.06, SE?=?2.67, p(adj)?=?1.000), and domain scores were not significant. Safety and tolerability data indicated that two children experienced gastrointestinal discomfort while taking CBD. Findings from this pilot trial suggest that while CBD combined with terpenes did not improve the primary outcome of social responsiveness, it may hold potential in addressing certain autism-related difficulties, particularly anxiety and social relating. Further research with larger sample sizes is needed to fully evaluate the efficacy and safety of CBD for autistic children. En ligne : https://doi.org/10.1002/aur.70159 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 Measurement Invariance of the PROMIS Family Relationships Scale Among Autistic and General Population Adolescents / Rachel M. BENECKE in Autism Research, 19-2 (February 2026)
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Titre : Measurement Invariance of the PROMIS Family Relationships Scale Among Autistic and General Population Adolescents Type de document : texte imprimé Auteurs : Rachel M. BENECKE, Auteur ; Zachary J. WILLIAMS, Auteur ; Laura Graham HOLMES, Auteur ; Judith S. MILLER, Auteur ; Elizabeth A. KAPLAN-KAHN, Auteur Article en page(s) : e70161 Langues : Anglais (eng) Mots-clés : adolescence autism family relationships measurement invariance patient-reported outcome measures PROMIS Index. décimale : PER Périodiques Résumé : ABSTRACT Social relationships are a key component of quality of life, a high-priority outcome for autistic people, and family relationships are critical in adolescence. The PROMIS Family Relationships scale has been well validated for use with the general population, but psychometric validation in the autistic population is lacking. This study investigated measurement invariance of the PROMIS Family Relationships among autistic and general population adolescents. The scale demonstrated scalar invariance between the groups, providing evidence that it measures the same construct equivalently and scores can be meaningfully compared between groups. With a well-validated self-report measure, researchers can ask autistic teens directly about their experiences of their family relationships, rather than relying solely on parent proxy report. En ligne : https://doi.org/10.1002/aur.70161 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70161[article] Measurement Invariance of the PROMIS Family Relationships Scale Among Autistic and General Population Adolescents [texte imprimé] / Rachel M. BENECKE, Auteur ; Zachary J. WILLIAMS, Auteur ; Laura Graham HOLMES, Auteur ; Judith S. MILLER, Auteur ; Elizabeth A. KAPLAN-KAHN, Auteur . - e70161.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70161
Mots-clés : adolescence autism family relationships measurement invariance patient-reported outcome measures PROMIS Index. décimale : PER Périodiques Résumé : ABSTRACT Social relationships are a key component of quality of life, a high-priority outcome for autistic people, and family relationships are critical in adolescence. The PROMIS Family Relationships scale has been well validated for use with the general population, but psychometric validation in the autistic population is lacking. This study investigated measurement invariance of the PROMIS Family Relationships among autistic and general population adolescents. The scale demonstrated scalar invariance between the groups, providing evidence that it measures the same construct equivalently and scores can be meaningfully compared between groups. With a well-validated self-report measure, researchers can ask autistic teens directly about their experiences of their family relationships, rather than relying solely on parent proxy report. En ligne : https://doi.org/10.1002/aur.70161 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 The Conceptualization, Experience, and Recognition of Emotion in Autism: Differences in the Psychological Mechanisms Involved in Autistic and Non-Autistic Emotion Recognition / Connor Tom KEATING in Autism Research, 19-2 (February 2026)
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Titre : The Conceptualization, Experience, and Recognition of Emotion in Autism: Differences in the Psychological Mechanisms Involved in Autistic and Non-Autistic Emotion Recognition Type de document : texte imprimé Auteurs : Connor Tom KEATING, Auteur ; Carmen KRAAIJKAMP, Auteur ; Jennifer Louise COOK, Auteur Article en page(s) : e70162 Langues : Anglais (eng) Mots-clés : autism concepts emotion facial expressions social cognition Index. décimale : PER Périodiques Résumé : ABSTRACT Existing literature suggests that differences between autistic and non-autistic people in emotion recognition might be related to differences in how these groups experience emotions themselves. Specifically, autistic individuals may show differences in the consistency of emotional experiences, the ability to distinguish between emotions, and/or their semantic understanding of emotions. In this study, we empirically tested this claim by (1) investigating whether autistic and non-autistic adults differed in the consistency and/or differentiation of their emotional experiences, and their understanding and differentiation of emotion concepts after controlling for alexithymia, and (2) assessing the contribution of these emotional abilities to emotion recognition. To this end, a total of 58 autistic and 59 non-autistic individuals, matched on age, sex, and non-verbal reasoning ability, completed a series of validated questionnaires and computer-based emotion tasks. We found no group differences in emotional consistency, emotion differentiation, and understanding or differentiation of emotion concepts after controlling for alexithymia. For non-autistic people, the ability to differentiate one's own emotions contributed to enhanced emotion recognition. Although having more differentiated emotion concepts (indirectly) contributed to elevated emotion recognition for non-autistic people, having a more precise understanding of emotion concepts contributed to emotion recognition for autistic people. Our findings demonstrate that there are differences in the psychological mechanisms involved in autistic and non-autistic emotion recognition. The results of the current study pave the way for future systems to help both autistic and non-autistic people to more accurately recognize emotional facial expressions. En ligne : https://doi.org/10.1002/aur.70162 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70162[article] The Conceptualization, Experience, and Recognition of Emotion in Autism: Differences in the Psychological Mechanisms Involved in Autistic and Non-Autistic Emotion Recognition [texte imprimé] / Connor Tom KEATING, Auteur ; Carmen KRAAIJKAMP, Auteur ; Jennifer Louise COOK, Auteur . - e70162.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70162
Mots-clés : autism concepts emotion facial expressions social cognition Index. décimale : PER Périodiques Résumé : ABSTRACT Existing literature suggests that differences between autistic and non-autistic people in emotion recognition might be related to differences in how these groups experience emotions themselves. Specifically, autistic individuals may show differences in the consistency of emotional experiences, the ability to distinguish between emotions, and/or their semantic understanding of emotions. In this study, we empirically tested this claim by (1) investigating whether autistic and non-autistic adults differed in the consistency and/or differentiation of their emotional experiences, and their understanding and differentiation of emotion concepts after controlling for alexithymia, and (2) assessing the contribution of these emotional abilities to emotion recognition. To this end, a total of 58 autistic and 59 non-autistic individuals, matched on age, sex, and non-verbal reasoning ability, completed a series of validated questionnaires and computer-based emotion tasks. We found no group differences in emotional consistency, emotion differentiation, and understanding or differentiation of emotion concepts after controlling for alexithymia. For non-autistic people, the ability to differentiate one's own emotions contributed to enhanced emotion recognition. Although having more differentiated emotion concepts (indirectly) contributed to elevated emotion recognition for non-autistic people, having a more precise understanding of emotion concepts contributed to emotion recognition for autistic people. Our findings demonstrate that there are differences in the psychological mechanisms involved in autistic and non-autistic emotion recognition. The results of the current study pave the way for future systems to help both autistic and non-autistic people to more accurately recognize emotional facial expressions. En ligne : https://doi.org/10.1002/aur.70162 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 The Impact of Inclusive Education Practices on Students With ASD'S Outcomes: Report From the ELENA French Cohort Study / Cécile RATTAZ in Autism Research, 19-2 (February 2026)
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Titre : The Impact of Inclusive Education Practices on Students With ASD'S Outcomes: Report From the ELENA French Cohort Study Type de document : texte imprimé Auteurs : Cécile RATTAZ, Auteur ; Marianne PERIES, Auteur ; Andrew PICKLES, Auteur ; Amaria BAGHDADLI, Auteur Article en page(s) : e70164 Langues : Anglais (eng) Mots-clés : adaptive skills autism spectrum disorders education inclusion outcome Index. décimale : PER Périodiques Résumé : ABSTRACT Inclusive education is largely promoted in the field of autism spectrum disorders (ASD), but scientific and empiric studies about the impact of school inclusion on the children's outcome are lacking. We studied the effect of the type of inclusion (regular classroom vs. special education classroom) in a sample of 356 children with ASD over a three-years period. Results first showed that, when comparing both groups at baseline, children in special education classes were older, had a higher level of challenging behaviors and came from lower socioeconomic status families. Once matched through propensity score, children in special classrooms had significantly lower communication and daily living skills than children in ordinary classrooms after 3?years, whereas there was no significant difference in socialization skills and in IQ. Overall, placement in a regular education classroom was positive for most children, however there is a high inter-individual variability and it is very unlikely that inclusive settings are by default superior for all children with special needs. These results, emphasizing the crucial role of the mainstream milieu, cannot be considered definitive and further studies are needed to address this critical educational policy issue. Trial Registration: ClinicalTrials.gov identifier: NCT02625116. En ligne : https://doi.org/10.1002/aur.70164 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70164[article] The Impact of Inclusive Education Practices on Students With ASD'S Outcomes: Report From the ELENA French Cohort Study [texte imprimé] / Cécile RATTAZ, Auteur ; Marianne PERIES, Auteur ; Andrew PICKLES, Auteur ; Amaria BAGHDADLI, Auteur . - e70164.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70164
Mots-clés : adaptive skills autism spectrum disorders education inclusion outcome Index. décimale : PER Périodiques Résumé : ABSTRACT Inclusive education is largely promoted in the field of autism spectrum disorders (ASD), but scientific and empiric studies about the impact of school inclusion on the children's outcome are lacking. We studied the effect of the type of inclusion (regular classroom vs. special education classroom) in a sample of 356 children with ASD over a three-years period. Results first showed that, when comparing both groups at baseline, children in special education classes were older, had a higher level of challenging behaviors and came from lower socioeconomic status families. Once matched through propensity score, children in special classrooms had significantly lower communication and daily living skills than children in ordinary classrooms after 3?years, whereas there was no significant difference in socialization skills and in IQ. Overall, placement in a regular education classroom was positive for most children, however there is a high inter-individual variability and it is very unlikely that inclusive settings are by default superior for all children with special needs. These results, emphasizing the crucial role of the mainstream milieu, cannot be considered definitive and further studies are needed to address this critical educational policy issue. Trial Registration: ClinicalTrials.gov identifier: NCT02625116. En ligne : https://doi.org/10.1002/aur.70164 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 Neurobehavioral Assessment of Sensorimotor Function in Autism Using Smartphone Technology / Kayleigh D. GULTIG in Autism Research, 19-2 (February 2026)
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Titre : Neurobehavioral Assessment of Sensorimotor Function in Autism Using Smartphone Technology Type de document : texte imprimé Auteurs : Kayleigh D. GULTIG, Auteur ; Cornelis P. BOELE, Auteur ; Lotte E. M. ROGGEVEEN, Auteur ; Ting Fang SOONG, Auteur ; Seth SHERRY, Auteur ; Caroline JUNG, Auteur ; Sara MILOSEVSKA, Auteur ; Anton UVAROV, Auteur ; Khalid BENHASSAN, Auteur ; Said Ait BENALI, Auteur ; Yasmine AHAJOUI, Auteur ; Valeria CARPIO-ARIAS, Auteur ; Sander LINDEMAN, Auteur ; Sebastiaan K. E. KOEKKOEK, Auteur ; Esra SEFIK, Auteur ; Myrthe J. OTTENHOFF, Auteur ; Samuel S. H. WANG, Auteur ; Chris I. DE ZEEUW, Auteur ; Abdeslem EL IDRISSI, Auteur ; Henk-Jan BOELE, Auteur Article en page(s) : e70166 Langues : Anglais (eng) Mots-clés : autism spectrum disorder neurodevelopmental disorders neurophysiological tests perception reflex startle Index. décimale : PER Périodiques Résumé : ABSTRACT Differences in sensorimotor processing represent an important, yet underrecognized, feature of autism; typically assessed through subjective observations, which, although important, are susceptible to biases. To complement these observations, a more objective approach to assess sensorimotor function may be possible through reflex-based neurobehavioral evaluations. The clinical application of these assessments has, however, been largely confined to laboratory settings. Thus, small sample sizes and inconsistent findings have made it challenging to understand how sensorimotor function differs in autism and whether it can be used as an objective biomarker for diagnostics. Here we present a novel smartphone-based platform to conduct neurobehavioral evaluations by measuring facial and behavioral responses in at-home environments. Through a multi-center study, we explored the platform's ability to distinguish between children with and without autism. We enrolled 536 children aged 3?12?years. BlinkLab smartphone-based assessments were successfully completed in 431 children (80.4%), including 275 with autism and 156 neurotypical children. We found that autistic children showed altered sensorimotor responses across multiple domains. These included reduced prepulse inhibition (PPI), stronger startle habituation over the course of a PPI test, more variable eyeblink responses to auditory stimuli and significant sensitization. Additionally, children with autism displayed more screen avoidance, postural instability, head movements, mouth openings, non-syllabic vocalizations, horizontal pupil shifts, ?side-eyeing?, and variation in baseline eyelid opening. Exploratory analyses showed that these effects were largely independent of co-occurring conditions. Notably, co-occurrence did influence certain subdomains (e.g., PPI, mouth openings). These findings illustrate that smartphone-based assessments can capture distinct sensorimotor profiles associated with autism in real-world environments. En ligne : https://doi.org/10.1002/aur.70166 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70166[article] Neurobehavioral Assessment of Sensorimotor Function in Autism Using Smartphone Technology [texte imprimé] / Kayleigh D. GULTIG, Auteur ; Cornelis P. BOELE, Auteur ; Lotte E. M. ROGGEVEEN, Auteur ; Ting Fang SOONG, Auteur ; Seth SHERRY, Auteur ; Caroline JUNG, Auteur ; Sara MILOSEVSKA, Auteur ; Anton UVAROV, Auteur ; Khalid BENHASSAN, Auteur ; Said Ait BENALI, Auteur ; Yasmine AHAJOUI, Auteur ; Valeria CARPIO-ARIAS, Auteur ; Sander LINDEMAN, Auteur ; Sebastiaan K. E. KOEKKOEK, Auteur ; Esra SEFIK, Auteur ; Myrthe J. OTTENHOFF, Auteur ; Samuel S. H. WANG, Auteur ; Chris I. DE ZEEUW, Auteur ; Abdeslem EL IDRISSI, Auteur ; Henk-Jan BOELE, Auteur . - e70166.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70166
Mots-clés : autism spectrum disorder neurodevelopmental disorders neurophysiological tests perception reflex startle Index. décimale : PER Périodiques Résumé : ABSTRACT Differences in sensorimotor processing represent an important, yet underrecognized, feature of autism; typically assessed through subjective observations, which, although important, are susceptible to biases. To complement these observations, a more objective approach to assess sensorimotor function may be possible through reflex-based neurobehavioral evaluations. The clinical application of these assessments has, however, been largely confined to laboratory settings. Thus, small sample sizes and inconsistent findings have made it challenging to understand how sensorimotor function differs in autism and whether it can be used as an objective biomarker for diagnostics. Here we present a novel smartphone-based platform to conduct neurobehavioral evaluations by measuring facial and behavioral responses in at-home environments. Through a multi-center study, we explored the platform's ability to distinguish between children with and without autism. We enrolled 536 children aged 3?12?years. BlinkLab smartphone-based assessments were successfully completed in 431 children (80.4%), including 275 with autism and 156 neurotypical children. We found that autistic children showed altered sensorimotor responses across multiple domains. These included reduced prepulse inhibition (PPI), stronger startle habituation over the course of a PPI test, more variable eyeblink responses to auditory stimuli and significant sensitization. Additionally, children with autism displayed more screen avoidance, postural instability, head movements, mouth openings, non-syllabic vocalizations, horizontal pupil shifts, ?side-eyeing?, and variation in baseline eyelid opening. Exploratory analyses showed that these effects were largely independent of co-occurring conditions. Notably, co-occurrence did influence certain subdomains (e.g., PPI, mouth openings). These findings illustrate that smartphone-based assessments can capture distinct sensorimotor profiles associated with autism in real-world environments. En ligne : https://doi.org/10.1002/aur.70166 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 Mother–Child Biobehavioral Synchrony and Its Association With Social Functioning in Autistic School-Aged Children / Carly MOSER in Autism Research, 19-2 (February 2026)
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[article]
Titre : Mother–Child Biobehavioral Synchrony and Its Association With Social Functioning in Autistic School-Aged Children Type de document : texte imprimé Auteurs : Carly MOSER, Auteur ; Chih-Hsiang YANG, Auteur ; Abigail L. HOGAN, Auteur ; Amanda FAIRCHILD, Auteur ; Jane ROBERTS, Auteur ; Jessica KLUSEK, Auteur Article en page(s) : e70168 Langues : Anglais (eng) Mots-clés : autism biobehavioral synchrony heart activity parent–child synchrony respiratory sinus arrhythmia social functioning Index. décimale : PER Périodiques Résumé : ABSTRACT Parent?child biobehavioral synchrony, or the concordance of behavior and physiological indicators between individuals, is theorized to support children's social development; however, this relationship has yet to be investigated in autistic children. This study examined whether moment-to-moment physiological synchrony?indexed via respiratory sinus arrhythmia (RSA)?and its interface with global levels of behavioral synchrony was associated with the pragmatic language skills and friendship quality of school-aged autistic children in 40 mother?child dyads. Mother?child dyads participated in a collaborative task, from which RSA synchrony and behavioral synchrony were assessed. Mothers and their autistic children demonstrated negative RSA synchrony, such that when one partner displayed an increase in RSA, the other partner showed a decrease in RSA. The extent of behavioral synchrony between mothers and their children did not moderate the strength of concordance between mother and child RSA. Negative RSA synchrony was associated with better pragmatic language skills in autistic children from mother?child dyads who displayed high levels of behavioral synchrony. These findings highlight the complexity of dyadic synchrony, suggesting that the coordination of mother?child RSA, in conjunction with behavioral synchrony, may aid in the development of social skills in autistic children that extend beyond the immediate caregiver context. However, larger longitudinal studies are needed to confirm this. En ligne : https://doi.org/10.1002/aur.70168 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70168[article] Mother–Child Biobehavioral Synchrony and Its Association With Social Functioning in Autistic School-Aged Children [texte imprimé] / Carly MOSER, Auteur ; Chih-Hsiang YANG, Auteur ; Abigail L. HOGAN, Auteur ; Amanda FAIRCHILD, Auteur ; Jane ROBERTS, Auteur ; Jessica KLUSEK, Auteur . - e70168.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70168
Mots-clés : autism biobehavioral synchrony heart activity parent–child synchrony respiratory sinus arrhythmia social functioning Index. décimale : PER Périodiques Résumé : ABSTRACT Parent?child biobehavioral synchrony, or the concordance of behavior and physiological indicators between individuals, is theorized to support children's social development; however, this relationship has yet to be investigated in autistic children. This study examined whether moment-to-moment physiological synchrony?indexed via respiratory sinus arrhythmia (RSA)?and its interface with global levels of behavioral synchrony was associated with the pragmatic language skills and friendship quality of school-aged autistic children in 40 mother?child dyads. Mother?child dyads participated in a collaborative task, from which RSA synchrony and behavioral synchrony were assessed. Mothers and their autistic children demonstrated negative RSA synchrony, such that when one partner displayed an increase in RSA, the other partner showed a decrease in RSA. The extent of behavioral synchrony between mothers and their children did not moderate the strength of concordance between mother and child RSA. Negative RSA synchrony was associated with better pragmatic language skills in autistic children from mother?child dyads who displayed high levels of behavioral synchrony. These findings highlight the complexity of dyadic synchrony, suggesting that the coordination of mother?child RSA, in conjunction with behavioral synchrony, may aid in the development of social skills in autistic children that extend beyond the immediate caregiver context. However, larger longitudinal studies are needed to confirm this. En ligne : https://doi.org/10.1002/aur.70168 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 Children With ASD Do Not Understand Hidden Emotions Before False Belief Attribution / Morgane BURNEL in Autism Research, 19-2 (February 2026)
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[article]
Titre : Children With ASD Do Not Understand Hidden Emotions Before False Belief Attribution Type de document : texte imprimé Auteurs : Morgane BURNEL, Auteur ; Stephanie DURRLEMAN, Auteur ; Anne REBOUL, Auteur ; Jean PYLOUSTER, Auteur ; Monica BACIU, Auteur ; Marcela PERRONE-BERTOLOTTI, Auteur Article en page(s) : e70170 Langues : Anglais (eng) Mots-clés : autism spectrum disorders development Guttman Rasch theory of mind Index. décimale : PER Périodiques Résumé : ABSTRACT Previous studies concluded that theory of mind (ToM) development is deviant in autism spectrum disorders (ASD). Typically developing children's ability to understand that one may hide their emotion would be acquired before false belief understanding in children with ASD (e.g., Peterson and Wellman 2019), but with contradictory results (e.g., Zhang et al. 2016). In the current work, we aim to determine whether the order of acquisition of ToM-related concepts in ASD differs, using methodological improvements compared to previous studies. Our results support the conclusion of a non-deviant developmental trajectory for ToM in individuals with ASD, with a general ability to understand hidden emotions that is not mastered before false belief attribution. En ligne : https://doi.org/10.1002/aur.70170 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70170[article] Children With ASD Do Not Understand Hidden Emotions Before False Belief Attribution [texte imprimé] / Morgane BURNEL, Auteur ; Stephanie DURRLEMAN, Auteur ; Anne REBOUL, Auteur ; Jean PYLOUSTER, Auteur ; Monica BACIU, Auteur ; Marcela PERRONE-BERTOLOTTI, Auteur . - e70170.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70170
Mots-clés : autism spectrum disorders development Guttman Rasch theory of mind Index. décimale : PER Périodiques Résumé : ABSTRACT Previous studies concluded that theory of mind (ToM) development is deviant in autism spectrum disorders (ASD). Typically developing children's ability to understand that one may hide their emotion would be acquired before false belief understanding in children with ASD (e.g., Peterson and Wellman 2019), but with contradictory results (e.g., Zhang et al. 2016). In the current work, we aim to determine whether the order of acquisition of ToM-related concepts in ASD differs, using methodological improvements compared to previous studies. Our results support the conclusion of a non-deviant developmental trajectory for ToM in individuals with ASD, with a general ability to understand hidden emotions that is not mastered before false belief attribution. En ligne : https://doi.org/10.1002/aur.70170 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 Head Growth Trajectories During the First Year of Life and Risk of Autism Spectrum Disorder / Rewaa BALAUM in Autism Research, 19-2 (February 2026)
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[article]
Titre : Head Growth Trajectories During the First Year of Life and Risk of Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Rewaa BALAUM, Auteur ; Leena ELBEDOUR, Auteur ; Einav ALHOZYEL, Auteur ; Gal MEIRI, Auteur ; Dikla ZIGDON, Auteur ; Analya MICHAELOVSKI, Auteur ; Orly KERUB, Auteur ; Idan MENASHE, Auteur Article en page(s) : e70172 Langues : Anglais (eng) Mots-clés : autism spectrum disorder growth trajectories head circumference height macrocephaly microcephaly Index. décimale : PER Périodiques Résumé : ABSTRACT Atypical infant head circumference (HC)?including increased rates of macrocephaly and microcephaly?has been linked to autism spectrum disorder (ASD). However, specific head growth trajectories associated with ASD remain poorly defined. This retrospective case?control study aimed to delineate these trajectories and examine their relationship to height. The study sample included 262 children diagnosed with ASD and 560 matched controls. Growth measures at 1, 2, 4, 6, 9, and 12?months of age were obtained from health clinics in southern Israel. The sample was classified into seven clusters based on HC patterns across these six time points, and associations with ASD were estimated using conditional logistic regression. Results demonstrated significant correlations between HC and height throughout the study period (Pearson correlation r?=?0.44?0.55, p?0.001), with stronger correlations in ASD (r?=?0.50?0.67) compared to controls (r?=?0.32?0.50). Children with consistently small or large HC exhibited the highest ASD likelihood (adjusted odds ratio [aOR]?=?2.95, 95% CI?=?1.88?4.94; and aOR?=?3.17, 95% CI?=?1.92?5.01, respectively), with the most extreme percentiles (0?5th and 95th?100th) showing the strongest associations (aOR?=?9.53, 95% CI?=?2.49?35.26; aOR?=?6.51, 95% CI?=?2.91?15.35, respectively). These associations were primarily driven by children with similar height trajectories (aOR?=?7.71, 95% CI?=?3.23?15.43; and aOR?=?6.89, 95% CI?=?2.99?13.26, respectively), indicating that atypical HC growth in ASD during infancy may reflect broader physiological growth dysregulation. En ligne : https://doi.org/10.1002/aur.70172 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70172[article] Head Growth Trajectories During the First Year of Life and Risk of Autism Spectrum Disorder [texte imprimé] / Rewaa BALAUM, Auteur ; Leena ELBEDOUR, Auteur ; Einav ALHOZYEL, Auteur ; Gal MEIRI, Auteur ; Dikla ZIGDON, Auteur ; Analya MICHAELOVSKI, Auteur ; Orly KERUB, Auteur ; Idan MENASHE, Auteur . - e70172.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70172
Mots-clés : autism spectrum disorder growth trajectories head circumference height macrocephaly microcephaly Index. décimale : PER Périodiques Résumé : ABSTRACT Atypical infant head circumference (HC)?including increased rates of macrocephaly and microcephaly?has been linked to autism spectrum disorder (ASD). However, specific head growth trajectories associated with ASD remain poorly defined. This retrospective case?control study aimed to delineate these trajectories and examine their relationship to height. The study sample included 262 children diagnosed with ASD and 560 matched controls. Growth measures at 1, 2, 4, 6, 9, and 12?months of age were obtained from health clinics in southern Israel. The sample was classified into seven clusters based on HC patterns across these six time points, and associations with ASD were estimated using conditional logistic regression. Results demonstrated significant correlations between HC and height throughout the study period (Pearson correlation r?=?0.44?0.55, p?0.001), with stronger correlations in ASD (r?=?0.50?0.67) compared to controls (r?=?0.32?0.50). Children with consistently small or large HC exhibited the highest ASD likelihood (adjusted odds ratio [aOR]?=?2.95, 95% CI?=?1.88?4.94; and aOR?=?3.17, 95% CI?=?1.92?5.01, respectively), with the most extreme percentiles (0?5th and 95th?100th) showing the strongest associations (aOR?=?9.53, 95% CI?=?2.49?35.26; aOR?=?6.51, 95% CI?=?2.91?15.35, respectively). These associations were primarily driven by children with similar height trajectories (aOR?=?7.71, 95% CI?=?3.23?15.43; and aOR?=?6.89, 95% CI?=?2.99?13.26, respectively), indicating that atypical HC growth in ASD during infancy may reflect broader physiological growth dysregulation. En ligne : https://doi.org/10.1002/aur.70172 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 Longitudinal Changes of the White Matter Microstructural Properties of Autism Spectrum Disorder: A Normative Model Analysis / Yi-Ling CHIEN in Autism Research, 19-2 (February 2026)
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[article]
Titre : Longitudinal Changes of the White Matter Microstructural Properties of Autism Spectrum Disorder: A Normative Model Analysis Type de document : texte imprimé Auteurs : Yi-Ling CHIEN, Auteur ; Wan-Ling TSENG, Auteur ; Chang-Le CHEN, Auteur ; Wen-Yih Isaac TSENG, Auteur ; Susan Shur-Fen GAU, Auteur Article en page(s) : e70174 Langues : Anglais (eng) Mots-clés : autism spectrum disorder developmental dysconnectivity diffusion spectrum imaging normative model white matter microstructure Index. décimale : PER Périodiques Résumé : ABSTRACT Cross-sectional research documents atypical age-related development of white matter in autism spectrum disorder (ASD). However, little is known about the developmental changes in white matter microstructural properties in ASD. This study aims to investigate developmental changes in white matter tract microstructural properties in ASD using a longitudinal follow-up design and normative model analysis, and to examine clinical correlates of these changes. We assessed 75 autistic individuals (aged 15.3?±?4.2?years) with diffusion spectrum imaging at baseline and 4.7?±?1.9?years later. To measure the magnitude of deviation from the norm, we calculated z-scores for fractional anisotropy (FA), axial diffusivity (AD), radial diffusivity (RD), and mean diffusivity (MD) for each of 76 tracts based on a norm established in 680 typically developing individuals. Callosal fibers connecting the temporal poles, hippocampus, and amygdala in ASD individuals showed higher AD, RD, and MD at both time points. Several tracts showed significantly greater increases in FA z-scores from baseline to follow-up, including the right superior longitudinal fasciculus, precentral thalamic radiation, frontal aslant tract, right corticospinal tracts, left arcuate fasciculus, callosal fibers connecting genu, and bilateral thalamic radiation, implying a pattern of greater deviation from the norm at Time 2 than Time 1. Higher autistic severity or social deficits at baseline were related to greater increasing rates in the diffusion metrics of callosal fibers connecting the precuneus (AD, RD, and MD), corticospinal tract (AD), right geniculate fibers (AD and MD), and right medial lemniscus (AD and MD) from baseline to follow-up. Using the normative model method to analyze longitudinal data on white matter microstructures, our findings support persistent alterations in callosal fibers and developmental alterations of several tracts in ASD, which were associated with baseline autistic severity. En ligne : https://doi.org/10.1002/aur.70174 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70174[article] Longitudinal Changes of the White Matter Microstructural Properties of Autism Spectrum Disorder: A Normative Model Analysis [texte imprimé] / Yi-Ling CHIEN, Auteur ; Wan-Ling TSENG, Auteur ; Chang-Le CHEN, Auteur ; Wen-Yih Isaac TSENG, Auteur ; Susan Shur-Fen GAU, Auteur . - e70174.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70174
Mots-clés : autism spectrum disorder developmental dysconnectivity diffusion spectrum imaging normative model white matter microstructure Index. décimale : PER Périodiques Résumé : ABSTRACT Cross-sectional research documents atypical age-related development of white matter in autism spectrum disorder (ASD). However, little is known about the developmental changes in white matter microstructural properties in ASD. This study aims to investigate developmental changes in white matter tract microstructural properties in ASD using a longitudinal follow-up design and normative model analysis, and to examine clinical correlates of these changes. We assessed 75 autistic individuals (aged 15.3?±?4.2?years) with diffusion spectrum imaging at baseline and 4.7?±?1.9?years later. To measure the magnitude of deviation from the norm, we calculated z-scores for fractional anisotropy (FA), axial diffusivity (AD), radial diffusivity (RD), and mean diffusivity (MD) for each of 76 tracts based on a norm established in 680 typically developing individuals. Callosal fibers connecting the temporal poles, hippocampus, and amygdala in ASD individuals showed higher AD, RD, and MD at both time points. Several tracts showed significantly greater increases in FA z-scores from baseline to follow-up, including the right superior longitudinal fasciculus, precentral thalamic radiation, frontal aslant tract, right corticospinal tracts, left arcuate fasciculus, callosal fibers connecting genu, and bilateral thalamic radiation, implying a pattern of greater deviation from the norm at Time 2 than Time 1. Higher autistic severity or social deficits at baseline were related to greater increasing rates in the diffusion metrics of callosal fibers connecting the precuneus (AD, RD, and MD), corticospinal tract (AD), right geniculate fibers (AD and MD), and right medial lemniscus (AD and MD) from baseline to follow-up. Using the normative model method to analyze longitudinal data on white matter microstructures, our findings support persistent alterations in callosal fibers and developmental alterations of several tracts in ASD, which were associated with baseline autistic severity. En ligne : https://doi.org/10.1002/aur.70174 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 Systematic Review and Meta-Analysis of Abnormal Pubertal Timing in Children With Autism Spectrum Disorder (ASD) / Li TIAN in Autism Research, 19-2 (February 2026)
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[article]
Titre : Systematic Review and Meta-Analysis of Abnormal Pubertal Timing in Children With Autism Spectrum Disorder (ASD) Type de document : texte imprimé Auteurs : Li TIAN, Auteur ; Zhiming HU, Auteur ; Ishimwe Angelique BAPTITIAN, Auteur ; Guoyong ZHAO, Auteur ; Lei GAO, Auteur Article en page(s) : e70182 Langues : Anglais (eng) Mots-clés : autism Spectrum disorder (ASD) meta-analysis precocious puberty (PP) pubertal timing Index. décimale : PER Périodiques Résumé : ABSTRACT This study aimed to synthesize evidence on the risk and patterns of abnormal pubertal timing, including precocious puberty (PP) and altered onset, in children with autism spectrum disorder (ASD) compared with typically developing (TD) peers. We conducted a systematic review and meta-analysis following the PRISMA guidelines, searching PubMed (n =?51), Web of Science (n =?91), and Cochrane Library (n =?19). After removing duplicates (n =?40), we screened 121 records and assessed 31 full-text articles, with 12 meeting the inclusion criteria (3 cohort studies on PP; 9 cohort studies on pubertal timing). Random-effects meta-analyses were performed to calculate pooled hazard ratios (HRs) for PP and standardized mean differences (SMDs) for pubertal timing. Study quality was assessed using the Newcastle-Ottawa Scale (NOS). Meta-analysis of three studies (42,017 ASD children; 3,424,004 TD children) revealed a significantly higher risk of PP in ASD children (pooled HR?=?3.64; 95% CI: 1.42?9.34; P =?0.007), with an absolute risk difference of 1.13% (prevalence: 1.2% in ASD vs. 0.07% in TD), indicating that 88 ASD children would need monitoring to identify one additional case of PP; this risk was particularly pronounced in females with ASD. In contrast, nine studies (856 ASD children; 648 TD children) found no significant overall difference in pubertal timing (SMD = ?0.22; 95% CI: ?0.91?0.46; P =?0.52), despite high heterogeneity (I2 =?96%). Funnel plot asymmetry suggested potential publication bias or methodological variations (e.g., confounder adjustments, diagnostic criteria). Sensitivity analysis confirmed the association between ASD and PP but highlighted instability in the effect size. Children with ASD exhibit a 3.6-fold increased relative risk of PP, particularly in females, though the absolute prevalence is low and the certainty of evidence is very low (per Grading of Recommendations Assessment, Development and Evaluation [GRADE] criteria), primarily due to high heterogeneity (I2 =?91%?96%) and potential biases. No consistent differences in pubertal timing were observed between ASD and TD children, likely reflecting methodological inconsistencies. Clinicians should enhance vigilance for PP in ASD children, without the need for routine screening. Future studies should adopt standardized, multi-method assessments to refine these findings. En ligne : https://doi.org/10.1002/aur.70182 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70182[article] Systematic Review and Meta-Analysis of Abnormal Pubertal Timing in Children With Autism Spectrum Disorder (ASD) [texte imprimé] / Li TIAN, Auteur ; Zhiming HU, Auteur ; Ishimwe Angelique BAPTITIAN, Auteur ; Guoyong ZHAO, Auteur ; Lei GAO, Auteur . - e70182.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70182
Mots-clés : autism Spectrum disorder (ASD) meta-analysis precocious puberty (PP) pubertal timing Index. décimale : PER Périodiques Résumé : ABSTRACT This study aimed to synthesize evidence on the risk and patterns of abnormal pubertal timing, including precocious puberty (PP) and altered onset, in children with autism spectrum disorder (ASD) compared with typically developing (TD) peers. We conducted a systematic review and meta-analysis following the PRISMA guidelines, searching PubMed (n =?51), Web of Science (n =?91), and Cochrane Library (n =?19). After removing duplicates (n =?40), we screened 121 records and assessed 31 full-text articles, with 12 meeting the inclusion criteria (3 cohort studies on PP; 9 cohort studies on pubertal timing). Random-effects meta-analyses were performed to calculate pooled hazard ratios (HRs) for PP and standardized mean differences (SMDs) for pubertal timing. Study quality was assessed using the Newcastle-Ottawa Scale (NOS). Meta-analysis of three studies (42,017 ASD children; 3,424,004 TD children) revealed a significantly higher risk of PP in ASD children (pooled HR?=?3.64; 95% CI: 1.42?9.34; P =?0.007), with an absolute risk difference of 1.13% (prevalence: 1.2% in ASD vs. 0.07% in TD), indicating that 88 ASD children would need monitoring to identify one additional case of PP; this risk was particularly pronounced in females with ASD. In contrast, nine studies (856 ASD children; 648 TD children) found no significant overall difference in pubertal timing (SMD = ?0.22; 95% CI: ?0.91?0.46; P =?0.52), despite high heterogeneity (I2 =?96%). Funnel plot asymmetry suggested potential publication bias or methodological variations (e.g., confounder adjustments, diagnostic criteria). Sensitivity analysis confirmed the association between ASD and PP but highlighted instability in the effect size. Children with ASD exhibit a 3.6-fold increased relative risk of PP, particularly in females, though the absolute prevalence is low and the certainty of evidence is very low (per Grading of Recommendations Assessment, Development and Evaluation [GRADE] criteria), primarily due to high heterogeneity (I2 =?91%?96%) and potential biases. No consistent differences in pubertal timing were observed between ASD and TD children, likely reflecting methodological inconsistencies. Clinicians should enhance vigilance for PP in ASD children, without the need for routine screening. Future studies should adopt standardized, multi-method assessments to refine these findings. En ligne : https://doi.org/10.1002/aur.70182 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 Letter to the Editor: Converging Approaches to Autistic Online Discourse / Brigitta KAKUSZI in Autism Research, 19-2 (February 2026)
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[article]
Titre : Letter to the Editor: Converging Approaches to Autistic Online Discourse Type de document : texte imprimé Auteurs : Brigitta KAKUSZI, Auteur ; Szilvia HETESY, Auteur ; Pál CZOBOR, Auteur Article en page(s) : e70183 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.70183 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70183[article] Letter to the Editor: Converging Approaches to Autistic Online Discourse [texte imprimé] / Brigitta KAKUSZI, Auteur ; Szilvia HETESY, Auteur ; Pál CZOBOR, Auteur . - e70183.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70183
Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.70183 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582 Response to: “Converging Approaches to Autistic Online Discourse” / Alessandro CAROLLO in Autism Research, 19-2 (February 2026)
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[article]
Titre : Response to: “Converging Approaches to Autistic Online Discourse” Type de document : texte imprimé Auteurs : Alessandro CAROLLO, Auteur ; Seraphina FONG, Auteur ; Giacomo VIVANTI, Auteur ; Daniel S. MESSINGER, Auteur ; Dagmara DIMITRIOU, Auteur ; Gianluca ESPOSITO, Auteur Article en page(s) : e70187 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.70187 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582
in Autism Research > 19-2 (February 2026) . - e70187[article] Response to: “Converging Approaches to Autistic Online Discourse” [texte imprimé] / Alessandro CAROLLO, Auteur ; Seraphina FONG, Auteur ; Giacomo VIVANTI, Auteur ; Daniel S. MESSINGER, Auteur ; Dagmara DIMITRIOU, Auteur ; Gianluca ESPOSITO, Auteur . - e70187.
Langues : Anglais (eng)
in Autism Research > 19-2 (February 2026) . - e70187
Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.70187 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=582

