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Auteur Russell SCHACHAR |
Documents disponibles écrits par cet auteur (13)



Association of Autism Spectrum Disorder with Obsessive-Compulsive and Attention-Deficit/Hyperactivity Traits and Response Inhibition in a Community Sample / Ellen VAN DER PLAS in Journal of Autism and Developmental Disorders, 46-9 (September 2016)
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Titre : Association of Autism Spectrum Disorder with Obsessive-Compulsive and Attention-Deficit/Hyperactivity Traits and Response Inhibition in a Community Sample Type de document : Texte imprimé et/ou numérique Auteurs : Ellen VAN DER PLAS, Auteur ; Annie DUPUIS, Auteur ; Paul ARNOLD, Auteur ; Jennifer CROSBIE, Auteur ; Russell SCHACHAR, Auteur Article en page(s) : p.3115-3125 Langues : Anglais (eng) Mots-clés : Autism Attention/deficits hyperactivity disorder Obsessive compulsive disorder Familial Traits Community sample Index. décimale : PER Périodiques Résumé : We examined co-occurrence of autism spectrum disorder (ASD) with (traits of) attention-deficit/hyperactivity (ADHD), obsessive-compulsive (OCD) and inhibition deficits in a community sample (n = 16,676) and tested whether having a sibling with ASD manifested in increased features of ADHD, OCD or inhibition deficits. Individuals with ASD had increased ADHD and OCD traits compared with individuals without ASD. Individuals with a sibling with ASD exhibited more ADHD traits than did individuals whose sibling did not have ASD. The “sibling effect” on manifestation of ADHD traits was observed in individuals with and without ASD. Having a sibling with ASD did not affect OCD traits. Inhibition was impaired in individuals with ASD who had a sibling with ASD only. En ligne : http://dx.doi.org/10.1007/s10803-016-2853-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=292
in Journal of Autism and Developmental Disorders > 46-9 (September 2016) . - p.3115-3125[article] Association of Autism Spectrum Disorder with Obsessive-Compulsive and Attention-Deficit/Hyperactivity Traits and Response Inhibition in a Community Sample [Texte imprimé et/ou numérique] / Ellen VAN DER PLAS, Auteur ; Annie DUPUIS, Auteur ; Paul ARNOLD, Auteur ; Jennifer CROSBIE, Auteur ; Russell SCHACHAR, Auteur . - p.3115-3125.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 46-9 (September 2016) . - p.3115-3125
Mots-clés : Autism Attention/deficits hyperactivity disorder Obsessive compulsive disorder Familial Traits Community sample Index. décimale : PER Périodiques Résumé : We examined co-occurrence of autism spectrum disorder (ASD) with (traits of) attention-deficit/hyperactivity (ADHD), obsessive-compulsive (OCD) and inhibition deficits in a community sample (n = 16,676) and tested whether having a sibling with ASD manifested in increased features of ADHD, OCD or inhibition deficits. Individuals with ASD had increased ADHD and OCD traits compared with individuals without ASD. Individuals with a sibling with ASD exhibited more ADHD traits than did individuals whose sibling did not have ASD. The “sibling effect” on manifestation of ADHD traits was observed in individuals with and without ASD. Having a sibling with ASD did not affect OCD traits. Inhibition was impaired in individuals with ASD who had a sibling with ASD only. En ligne : http://dx.doi.org/10.1007/s10803-016-2853-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=292 Cerebellar gamma-aminobutyric acid: Investigation of group effects in neurodevelopmental disorders / Elizabeth W. PANG in Autism Research, 16-3 (March 2023)
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Titre : Cerebellar gamma-aminobutyric acid: Investigation of group effects in neurodevelopmental disorders Type de document : Texte imprimé et/ou numérique Auteurs : Elizabeth W. PANG, Auteur ; Chris HAMMILL, Auteur ; Margot J. TAYLOR, Auteur ; Jamie NEAR, Auteur ; Russell SCHACHAR, Auteur ; Jennifer CROSBIE, Auteur ; Paul D. ARNOLD, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Jason P. LERCH, Auteur Article en page(s) : p.535-542 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Neurodevelopmental disorders (NDDs) including autism spectrum disorder (ASD), attention-deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD) are thought to arise in part from the disruption in the excitatory/inhibitory balance of gamma-aminobutyric acid (GABA) and glutamate in the brain. Recent evidence has shown the involvement of the cerebellum in cognition and affect regulation, and cerebellar atypical function or damage is reported frequently in NDDs. Magnetic resonance spectroscopy studies have reported decreases in GABA in cortical brain areas in the NDDs, however, GABA levels in the cerebellum have not been examined. To determine possible group effects, we used a MEGA-PRESS acquisition to investigate GABA+ levels in a cerebellar voxel in 343 individuals (aged 2.5-22?years) with ASD, ADHD, OCD and controls. Using a mixed effects model, we found no significant differences between groups in GABA+ concentration. Our findings suggest that cerebellar GABA+ levels do not differentiate NDD groups. En ligne : https://doi.org/10.1002/aur.2888 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=498
in Autism Research > 16-3 (March 2023) . - p.535-542[article] Cerebellar gamma-aminobutyric acid: Investigation of group effects in neurodevelopmental disorders [Texte imprimé et/ou numérique] / Elizabeth W. PANG, Auteur ; Chris HAMMILL, Auteur ; Margot J. TAYLOR, Auteur ; Jamie NEAR, Auteur ; Russell SCHACHAR, Auteur ; Jennifer CROSBIE, Auteur ; Paul D. ARNOLD, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Jason P. LERCH, Auteur . - p.535-542.
Langues : Anglais (eng)
in Autism Research > 16-3 (March 2023) . - p.535-542
Index. décimale : PER Périodiques Résumé : Abstract Neurodevelopmental disorders (NDDs) including autism spectrum disorder (ASD), attention-deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD) are thought to arise in part from the disruption in the excitatory/inhibitory balance of gamma-aminobutyric acid (GABA) and glutamate in the brain. Recent evidence has shown the involvement of the cerebellum in cognition and affect regulation, and cerebellar atypical function or damage is reported frequently in NDDs. Magnetic resonance spectroscopy studies have reported decreases in GABA in cortical brain areas in the NDDs, however, GABA levels in the cerebellum have not been examined. To determine possible group effects, we used a MEGA-PRESS acquisition to investigate GABA+ levels in a cerebellar voxel in 343 individuals (aged 2.5-22?years) with ASD, ADHD, OCD and controls. Using a mixed effects model, we found no significant differences between groups in GABA+ concentration. Our findings suggest that cerebellar GABA+ levels do not differentiate NDD groups. En ligne : https://doi.org/10.1002/aur.2888 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=498 Characterizing the ASD-ADHD phenotype: measurement structure and invariance in a clinical sample / Aneta D. KRAKOWSKI in Journal of Child Psychology and Psychiatry, 63-12 (December 2022)
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Titre : Characterizing the ASD-ADHD phenotype: measurement structure and invariance in a clinical sample Type de document : Texte imprimé et/ou numérique Auteurs : Aneta D. KRAKOWSKI, Auteur ; Katherine Tombeau COST, Auteur ; Peter SZATMARI, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Jennifer CROSBIE, Auteur ; Russell SCHACHAR, Auteur ; Eric DUKU, Auteur ; Stelios GEORGIADES, Auteur ; Muhammad AYUB, Auteur ; Elizabeth KELLEY, Auteur ; Rob NICOLSON, Auteur ; Eleanor PULLENAYEGUM, Auteur ; Carolina BARNETT-TAPIA, Auteur Article en page(s) : p.1534-1543 Langues : Anglais (eng) Mots-clés : Humans Attention Deficit Disorder with Hyperactivity/diagnosis/genetics Autism Spectrum Disorder/diagnosis Parents Phenotype Surveys and Questionnaires Adhd Asd factor analysis measurement invariance measurement structure Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD) have considerable overlap, supporting the need for a dimensional framework that examines neurodevelopmental domains which cross traditional diagnostic boundaries. In the following study, we use factor analysis to deconstruct the ASD-ADHD phenotype into its underlying phenotypic domains and test for measurement invariance across adaptive functioning, age, gender and ASD/ADHD clinical diagnoses. METHODS: Participants included children and youth (aged 3-20 years) with a clinical diagnosis of ASD (n=727) or ADHD (n=770) for a total of 1,497 participants. Parents of these children completed the Social Communication Questionnaire (SCQ), a measure of autism symptoms, and the Strengths and Weaknesses of ADHD and Normal Behaviour (SWAN) questionnaire, a measure of ADHD symptoms. An exploratory factor analysis (EFA) was performed on combined SCQ and SWAN items. This was followed by a confirmatory factor analysis (CFA) and tests of measurement invariance. RESULTS: EFA revealed a four-factor solution (inattention, hyperactivity/impulsivity, social-communication, and restricted, repetitive, behaviours and interests (RRBI)) and a CFA confirmed good model fit. This solution also showed good model fit across subgroups of interest. CONCLUSIONS: Our study shows that a combined ASD-ADHD phenotype is characterized by two latent ASD domains (social communication and RRBIs) and two latent ADHD domains (inattention and hyperactivity/impulsivity). We established measurement invariance of the derived measurement model across adaptive functioning, age, gender and ASD/ADHD diagnoses. En ligne : http://dx.doi.org/10.1111/jcpp.13609 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490
in Journal of Child Psychology and Psychiatry > 63-12 (December 2022) . - p.1534-1543[article] Characterizing the ASD-ADHD phenotype: measurement structure and invariance in a clinical sample [Texte imprimé et/ou numérique] / Aneta D. KRAKOWSKI, Auteur ; Katherine Tombeau COST, Auteur ; Peter SZATMARI, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Jennifer CROSBIE, Auteur ; Russell SCHACHAR, Auteur ; Eric DUKU, Auteur ; Stelios GEORGIADES, Auteur ; Muhammad AYUB, Auteur ; Elizabeth KELLEY, Auteur ; Rob NICOLSON, Auteur ; Eleanor PULLENAYEGUM, Auteur ; Carolina BARNETT-TAPIA, Auteur . - p.1534-1543.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 63-12 (December 2022) . - p.1534-1543
Mots-clés : Humans Attention Deficit Disorder with Hyperactivity/diagnosis/genetics Autism Spectrum Disorder/diagnosis Parents Phenotype Surveys and Questionnaires Adhd Asd factor analysis measurement invariance measurement structure Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD) have considerable overlap, supporting the need for a dimensional framework that examines neurodevelopmental domains which cross traditional diagnostic boundaries. In the following study, we use factor analysis to deconstruct the ASD-ADHD phenotype into its underlying phenotypic domains and test for measurement invariance across adaptive functioning, age, gender and ASD/ADHD clinical diagnoses. METHODS: Participants included children and youth (aged 3-20 years) with a clinical diagnosis of ASD (n=727) or ADHD (n=770) for a total of 1,497 participants. Parents of these children completed the Social Communication Questionnaire (SCQ), a measure of autism symptoms, and the Strengths and Weaknesses of ADHD and Normal Behaviour (SWAN) questionnaire, a measure of ADHD symptoms. An exploratory factor analysis (EFA) was performed on combined SCQ and SWAN items. This was followed by a confirmatory factor analysis (CFA) and tests of measurement invariance. RESULTS: EFA revealed a four-factor solution (inattention, hyperactivity/impulsivity, social-communication, and restricted, repetitive, behaviours and interests (RRBI)) and a CFA confirmed good model fit. This solution also showed good model fit across subgroups of interest. CONCLUSIONS: Our study shows that a combined ASD-ADHD phenotype is characterized by two latent ASD domains (social communication and RRBIs) and two latent ADHD domains (inattention and hyperactivity/impulsivity). We established measurement invariance of the derived measurement model across adaptive functioning, age, gender and ASD/ADHD diagnoses. En ligne : http://dx.doi.org/10.1111/jcpp.13609 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490 Concurrent Validity of the ABAS-II Questionnaire with the Vineland II Interview for Adaptive Behavior in a Pediatric ASD Sample: High Correspondence Despite Systematically Lower Scores / Annie DUPUIS in Journal of Autism and Developmental Disorders, 51-5 (May 2021)
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Titre : Concurrent Validity of the ABAS-II Questionnaire with the Vineland II Interview for Adaptive Behavior in a Pediatric ASD Sample: High Correspondence Despite Systematically Lower Scores Type de document : Texte imprimé et/ou numérique Auteurs : Annie DUPUIS, Auteur ; Michael J. MOON, Auteur ; Jessica BRIAN, Auteur ; Stelios GEORGIADES, Auteur ; Tomer LEVY, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Rob NICOLSON, Auteur ; Russell SCHACHAR, Auteur ; Jennifer CROSBIE, Auteur Article en page(s) : p.1417-1427 Langues : Anglais (eng) Mots-clés : Abas Adaptive behaviors Autism spectrum disorder Children Vineland Index. décimale : PER Périodiques Résumé : We examined the correlation between interviewer-administered Vineland Adaptive Behavior Scale II (VABS-II) and the parent-rated Adaptive Behavior Assessment System II (ABAS-II) questionnaire in 352 participants (ages 1.5-20.8 years) with autism spectrum disorder (ASD) to determine if ABAS could be used as a screen to reduce the number of VABS interviews. Corresponding domain scores between the two measures were highly correlated but scores were significantly lower on the ABAS-II. Screening with ABAS-II significantly reduced the number of VABS-II interviews required with little cost to overall accuracy. The ABAS-II provides a cost- and time-saving alternative to the VABS-II to rule out functional impairment; however, scores are not strictly comparable between the two measures. En ligne : http://dx.doi.org/10.1007/s10803-020-04597-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=445
in Journal of Autism and Developmental Disorders > 51-5 (May 2021) . - p.1417-1427[article] Concurrent Validity of the ABAS-II Questionnaire with the Vineland II Interview for Adaptive Behavior in a Pediatric ASD Sample: High Correspondence Despite Systematically Lower Scores [Texte imprimé et/ou numérique] / Annie DUPUIS, Auteur ; Michael J. MOON, Auteur ; Jessica BRIAN, Auteur ; Stelios GEORGIADES, Auteur ; Tomer LEVY, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Rob NICOLSON, Auteur ; Russell SCHACHAR, Auteur ; Jennifer CROSBIE, Auteur . - p.1417-1427.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 51-5 (May 2021) . - p.1417-1427
Mots-clés : Abas Adaptive behaviors Autism spectrum disorder Children Vineland Index. décimale : PER Périodiques Résumé : We examined the correlation between interviewer-administered Vineland Adaptive Behavior Scale II (VABS-II) and the parent-rated Adaptive Behavior Assessment System II (ABAS-II) questionnaire in 352 participants (ages 1.5-20.8 years) with autism spectrum disorder (ASD) to determine if ABAS could be used as a screen to reduce the number of VABS interviews. Corresponding domain scores between the two measures were highly correlated but scores were significantly lower on the ABAS-II. Screening with ABAS-II significantly reduced the number of VABS-II interviews required with little cost to overall accuracy. The ABAS-II provides a cost- and time-saving alternative to the VABS-II to rule out functional impairment; however, scores are not strictly comparable between the two measures. En ligne : http://dx.doi.org/10.1007/s10803-020-04597-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=445 Factor Structure of Repetitive Behaviors Across Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder / N. J. BRIERLEY in Journal of Autism and Developmental Disorders, 51-10 (October 2021)
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Titre : Factor Structure of Repetitive Behaviors Across Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder Type de document : Texte imprimé et/ou numérique Auteurs : N. J. BRIERLEY, Auteur ; C. G. MCDONNELL, Auteur ; K. M. A. PARKS, Auteur ; S. E. SCHULZ, Auteur ; T. C. DALAL, Auteur ; E. KELLEY, Auteur ; Evdokia ANAGNOSTOU, Auteur ; R. NICOLSON, Auteur ; S. GEORGIADES, Auteur ; J. CROSBIE, Auteur ; Russell SCHACHAR, Auteur ; X. LIU, Auteur ; R. A. STEVENSON, Auteur Article en page(s) : p.3391-3400 Langues : Anglais (eng) Mots-clés : Attention Deficit Disorder with Hyperactivity/diagnosis/epidemiology Autism Spectrum Disorder/diagnosis Child Female Humans Stereotyped Behavior Attention deficit/hyperactivity disorder Autism spectrum disorder Factor analysis Restricted and repetitive behaviors Index. décimale : PER Périodiques Résumé : Restricted interests and repetitive behaviors (RRBs) are core symptoms of autism spectrum disorder (ASD), and commonly occur in attention-deficit/hyperactivity disorder (ADHD). Little is known about how RRBs manifest in ADHD. We quantified and compared factor structures of RRBs in children with ASD (n?=?634) or ADHD (n?=?448), and related factors to sex and IQ. A four-factor solution emerged, including Stereotypy, Self-Injury, Compulsions, and Ritualistic/Sameness. Factor structures were equivalent across diagnoses, though symptoms were more severe in ASD. IQ negatively correlated with Stereotypy, Self-Injury, and Compulsions in ASD, and negatively correlated with Compulsions and Ritualistic/Sameness behaviors in ADHD. In ASD only, females exhibited higher Self-Injury. Thus, patterns of RRBs are preserved across ASD and ADHD, but severity and relationship with IQ differed. En ligne : http://dx.doi.org/10.1007/s10803-020-04800-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453
in Journal of Autism and Developmental Disorders > 51-10 (October 2021) . - p.3391-3400[article] Factor Structure of Repetitive Behaviors Across Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder [Texte imprimé et/ou numérique] / N. J. BRIERLEY, Auteur ; C. G. MCDONNELL, Auteur ; K. M. A. PARKS, Auteur ; S. E. SCHULZ, Auteur ; T. C. DALAL, Auteur ; E. KELLEY, Auteur ; Evdokia ANAGNOSTOU, Auteur ; R. NICOLSON, Auteur ; S. GEORGIADES, Auteur ; J. CROSBIE, Auteur ; Russell SCHACHAR, Auteur ; X. LIU, Auteur ; R. A. STEVENSON, Auteur . - p.3391-3400.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 51-10 (October 2021) . - p.3391-3400
Mots-clés : Attention Deficit Disorder with Hyperactivity/diagnosis/epidemiology Autism Spectrum Disorder/diagnosis Child Female Humans Stereotyped Behavior Attention deficit/hyperactivity disorder Autism spectrum disorder Factor analysis Restricted and repetitive behaviors Index. décimale : PER Périodiques Résumé : Restricted interests and repetitive behaviors (RRBs) are core symptoms of autism spectrum disorder (ASD), and commonly occur in attention-deficit/hyperactivity disorder (ADHD). Little is known about how RRBs manifest in ADHD. We quantified and compared factor structures of RRBs in children with ASD (n?=?634) or ADHD (n?=?448), and related factors to sex and IQ. A four-factor solution emerged, including Stereotypy, Self-Injury, Compulsions, and Ritualistic/Sameness. Factor structures were equivalent across diagnoses, though symptoms were more severe in ASD. IQ negatively correlated with Stereotypy, Self-Injury, and Compulsions in ASD, and negatively correlated with Compulsions and Ritualistic/Sameness behaviors in ADHD. In ASD only, females exhibited higher Self-Injury. Thus, patterns of RRBs are preserved across ASD and ADHD, but severity and relationship with IQ differed. En ligne : http://dx.doi.org/10.1007/s10803-020-04800-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453 Inattention and hyperactive/impulsive component scores do not differentiate between autism spectrum disorder and attention-deficit/hyperactivity disorder in a clinical sample / Aneta D. KRAKOWSKI in Molecular Autism, 11 (2020)
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PermalinkMagnetoencephalographic (MEG) brain activity during a mental flexibility task suggests some shared neurobiology in children with neurodevelopmental disorders / A. MOGADAM in Journal of Neurodevelopmental Disorders, 11-1 (December 2019)
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PermalinkObsessive-compulsive disorder in children and youth: neurocognitive function in clinic and community samples / Russell SCHACHAR in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)
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PermalinkPerformance monitoring in children following traumatic brain injury / Tisha J. ORNSTEIN in Journal of Child Psychology and Psychiatry, 50-4 (April 2009)
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PermalinkSerotonin system genes and obsessive-compulsive trait dimensions in a population-based, pediatric sample: a genetic association study / V. M. SINOPOLI in Journal of Child Psychology and Psychiatry, 60-12 (December 2019)
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PermalinkSWAN scale for ADHD trait-based genetic research: a validity and polygenic risk study / C. L. BURTON in Journal of Child Psychology and Psychiatry, 60-9 (September 2019)
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PermalinkThe persistence of cognitive deficits in remitted and unremitted ADHD: a case for the state-independence of response inhibition / Tara MCAULEY in Journal of Child Psychology and Psychiatry, 55-3 (March 2014)
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PermalinkTransdiagnostic Patterns of Sensory Processing in Autism and ADHD / Anahid POURTOUSI ; Connie YANG ; Zining DING ; Bobby STOJANOSKI ; Evdokia ANAGNOSTOU ; Robert NICOLSON ; Elizabeth KELLEY ; Stelios GEORGIADES ; Jennifer CROSBIE ; Russell SCHACHAR ; Muhammad AYUB ; Ryan A. STEVENSON in Journal of Autism and Developmental Disorders, 54-1 (January 2024)
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