Dépouillements

Editorial: Integrating multilevel environmental influences on child brain development / Divyangana RAKESH in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1221-1223 Titre : Editorial: Integrating multilevel environmental influences on child brain development Type de document : texte imprimé Auteurs : Divyangana RAKESH, Auteur ; Alexis BRIEANT, Auteur ; Katie A. MCLAUGHLIN, Auteur Article en page(s) : p.1221-1223 Langues : Anglais (eng) Mots-clés : Brain development  Stress  Childhood and adolescence  Family, neighborhood, and structural determinants  Interactions and developmental timing Index. décimale : PER Périodiques Résumé : Environmental influences on child brain development operate across multiple levels of context, including family, neighbourhood and broader structural environments. While developmental cognitive neuroscience has generated substantial evidence linking proximal experiences to neurodevelopment, neighbourhood and especially macrolevel structural influences remain less well-integrated into prevailing models. In this editorial, we argue for a multilevel developmental framework that considers the independent and interactive effects of environmental factors across contexts and how their influence changes over development. We highlight evidence that proximal, neighbourhood and structural conditions each contribute to neurodevelopment and that their effects are often interdependent. Advancing the field will require greater integration across levels of analysis to better understand how environments shape brain and behaviour development. En ligne : https://doi.org/10.1111/jcpp.70187 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591 [article] Editorial: Integrating multilevel environmental influences on child brain development [texte imprimé] / Divyangana RAKESH, Auteur ; Alexis BRIEANT, Auteur ; Katie A. MCLAUGHLIN, Auteur . - p.1221-1223. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1221-1223 Mots-clés : Brain development  Stress  Childhood and adolescence  Family, neighborhood, and structural determinants  Interactions and developmental timing Index. décimale : PER Périodiques Résumé : Environmental influences on child brain development operate across multiple levels of context, including family, neighbourhood and broader structural environments. While developmental cognitive neuroscience has generated substantial evidence linking proximal experiences to neurodevelopment, neighbourhood and especially macrolevel structural influences remain less well-integrated into prevailing models. In this editorial, we argue for a multilevel developmental framework that considers the independent and interactive effects of environmental factors across contexts and how their influence changes over development. We highlight evidence that proximal, neighbourhood and structural conditions each contribute to neurodevelopment and that their effects are often interdependent. Advancing the field will require greater integration across levels of analysis to better understand how environments shape brain and behaviour development. En ligne : https://doi.org/10.1111/jcpp.70187 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591

Effects of parent–child interaction therapy dosage on child and parent outcomes: differentiating child-directed interaction and parent-directed interaction session impacts in child welfare-involved families / Xiaolan LIAO in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1224-1243 Titre : Effects of parent–child interaction therapy dosage on child and parent outcomes: differentiating child-directed interaction and parent-directed interaction session impacts in child welfare-involved families Type de document : texte imprimé Auteurs : Xiaolan LIAO, Auteur ; Julia P. RUGGIERO, Auteur ; David E. BARD, Auteur ; Adon F.G. ROSEN, Auteur ; Elizabeth A. SKOWRON, Auteur Article en page(s) : p.1224-1243 Langues : Anglais (eng) Mots-clés : PCIT  treatment dosage  parenting  child welfare  RCT Index. décimale : PER Périodiques Résumé : Background Parent?child interaction therapy (PCIT) improves parenting and child behavior, yet little is known about how dosage of its two phases, warm relationship building focused child-directed interaction (CDI) sessions and safe, effective discipline skills-focused parent-directed interaction (PDI) sessions, contributes to outcomes, particularly in child welfare-involved families. Understanding these dose?response patterns can clarify the pathways through which PCIT produces change. Methods In a sample of 204 child welfare families with young children, we examined the dose?response relationship between each PCIT phase and key intervention outcomes of positive and negative parenting skills and disruptive child behavior problems. We also used sequential mediation models to test time-ordered intervention dosage effects (i.e., number of CDI sessions completed and subsequent number of PDI sessions completed) on the parent and child outcomes. Results Sequential mediation models showed that the PCIT intervention exerted significant indirect effects on increased positive parenting skills and decreased negative parenting behaviors and child behavior problems through higher dosage of relationship-enhancing CDI sessions followed by higher dosage of safe discipline-focused PDI sessions. Further, CDI dosage interacted with PDI dosage to predict greater gains in positive parenting skills outcomes. Conclusions These results contribute new insights into the pathways through which PCIT shapes outcomes in a sample of child welfare-involved families. Findings also highlight the significant unique contribution that limit-setting-oriented PDI, a relatively understudied phase of PCIT, plays in enhancing positive parenting skills and mitigating child behavior problems. En ligne : https://doi.org/10.1111/jcpp.70106 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591 [article] Effects of parent–child interaction therapy dosage on child and parent outcomes: differentiating child-directed interaction and parent-directed interaction session impacts in child welfare-involved families [texte imprimé] / Xiaolan LIAO, Auteur ; Julia P. RUGGIERO, Auteur ; David E. BARD, Auteur ; Adon F.G. ROSEN, Auteur ; Elizabeth A. SKOWRON, Auteur . - p.1224-1243. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1224-1243 Mots-clés : PCIT  treatment dosage  parenting  child welfare  RCT Index. décimale : PER Périodiques Résumé : Background Parent?child interaction therapy (PCIT) improves parenting and child behavior, yet little is known about how dosage of its two phases, warm relationship building focused child-directed interaction (CDI) sessions and safe, effective discipline skills-focused parent-directed interaction (PDI) sessions, contributes to outcomes, particularly in child welfare-involved families. Understanding these dose?response patterns can clarify the pathways through which PCIT produces change. Methods In a sample of 204 child welfare families with young children, we examined the dose?response relationship between each PCIT phase and key intervention outcomes of positive and negative parenting skills and disruptive child behavior problems. We also used sequential mediation models to test time-ordered intervention dosage effects (i.e., number of CDI sessions completed and subsequent number of PDI sessions completed) on the parent and child outcomes. Results Sequential mediation models showed that the PCIT intervention exerted significant indirect effects on increased positive parenting skills and decreased negative parenting behaviors and child behavior problems through higher dosage of relationship-enhancing CDI sessions followed by higher dosage of safe discipline-focused PDI sessions. Further, CDI dosage interacted with PDI dosage to predict greater gains in positive parenting skills outcomes. Conclusions These results contribute new insights into the pathways through which PCIT shapes outcomes in a sample of child welfare-involved families. Findings also highlight the significant unique contribution that limit-setting-oriented PDI, a relatively understudied phase of PCIT, plays in enhancing positive parenting skills and mitigating child behavior problems. En ligne : https://doi.org/10.1111/jcpp.70106 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591

Longitudinal associations between violence exposure and adolescent conduct problems in a high-adversity, South African setting / Susan SWINGLER in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1244-1253 Titre : Longitudinal associations between violence exposure and adolescent conduct problems in a high-adversity, South African setting Type de document : texte imprimé Auteurs : Susan SWINGLER, Auteur ; Qing HAN, Auteur ; Alexis E. CULLEN, Auteur ; Stefani DU TOIT, Auteur ; Sarah SKEEN, Auteur ; Jane BARLOW, Auteur ; Mark TOMLINSON, Auteur Article en page(s) : p.1244-1253 Langues : Anglais (eng) Mots-clés : Childhood trauma  externalising problems  youth  prospective study Index. décimale : PER Périodiques Résumé : Background Violence exposure is a well-established risk factor for adolescent conduct problems, yet longitudinal research in high-adversity, low- and middle-income countries (LMICs) remains limited. This study investigated whether early adolescent violence exposure predicts concurrent and longer-term conduct problems, and explored potential bidirectional associations and sex differences in a peri-urban South African community with high rates of poverty and violence. Methods Data were drawn from the Thula Sana birth cohort (n?=?357; 51.5% female), a longitudinal intervention study in Khayelitsha, South Africa. Adolescents were assessed at early (ages 12?14) and late adolescence (ages 16?19). Violence exposure was measured using adolescent self-report. Conduct problems were measured using adolescent and caregiver report in early adolescence and adolescent self-report in late adolescence. Multiple linear regressions tested cross-sectional associations, and cross-lagged panel models examined longitudinal and bidirectional associations, adjusting for contextual adversity and intervention status. Missing data were addressed using multiple imputation, and findings were confirmed through sensitivity analyses. Results Violence exposure was associated with higher concurrent conduct problems in early adolescence (??=?.15?.19, p??.05). Interaction analyses did not provide evidence that associations differed by sex. Conclusions Violence exposure in early adolescence represents a prospective risk factor for conduct problems in a high-adversity South African setting. Findings highlight the importance of early, contextually grounded violence prevention and the need for further research to test sex-specific pathways and inform the development of gender-responsive intervention strategies. En ligne : https://doi.org/10.1111/jcpp.70132 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591 [article] Longitudinal associations between violence exposure and adolescent conduct problems in a high-adversity, South African setting [texte imprimé] / Susan SWINGLER, Auteur ; Qing HAN, Auteur ; Alexis E. CULLEN, Auteur ; Stefani DU TOIT, Auteur ; Sarah SKEEN, Auteur ; Jane BARLOW, Auteur ; Mark TOMLINSON, Auteur . - p.1244-1253. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1244-1253 Mots-clés : Childhood trauma  externalising problems  youth  prospective study Index. décimale : PER Périodiques Résumé : Background Violence exposure is a well-established risk factor for adolescent conduct problems, yet longitudinal research in high-adversity, low- and middle-income countries (LMICs) remains limited. This study investigated whether early adolescent violence exposure predicts concurrent and longer-term conduct problems, and explored potential bidirectional associations and sex differences in a peri-urban South African community with high rates of poverty and violence. Methods Data were drawn from the Thula Sana birth cohort (n?=?357; 51.5% female), a longitudinal intervention study in Khayelitsha, South Africa. Adolescents were assessed at early (ages 12?14) and late adolescence (ages 16?19). Violence exposure was measured using adolescent self-report. Conduct problems were measured using adolescent and caregiver report in early adolescence and adolescent self-report in late adolescence. Multiple linear regressions tested cross-sectional associations, and cross-lagged panel models examined longitudinal and bidirectional associations, adjusting for contextual adversity and intervention status. Missing data were addressed using multiple imputation, and findings were confirmed through sensitivity analyses. Results Violence exposure was associated with higher concurrent conduct problems in early adolescence (??=?.15?.19, p??.05). Interaction analyses did not provide evidence that associations differed by sex. Conclusions Violence exposure in early adolescence represents a prospective risk factor for conduct problems in a high-adversity South African setting. Findings highlight the importance of early, contextually grounded violence prevention and the need for further research to test sex-specific pathways and inform the development of gender-responsive intervention strategies. En ligne : https://doi.org/10.1111/jcpp.70132 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591

The randomized controlled trial Fast Track multilevel intervention for children with early-emerging conduct problems breaks intergenerational transmission of violence across three generations / Laura GORLA in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1254-1268 Titre : The randomized controlled trial Fast Track multilevel intervention for children with early-emerging conduct problems breaks intergenerational transmission of violence across three generations Type de document : texte imprimé Auteurs : Laura GORLA, Auteur ; W. Andrew ROTHENBERG, Auteur ; Jennifer GODWIN, Auteur ; Group CONDUCT PROBLEMS PREVENTION RESEARCH, Auteur Article en page(s) : p.1254-1268 Langues : Anglais (eng) Mots-clés : intergenerational  intimate partner violence  parent-to-child violence  intervention Index. décimale : PER Périodiques Résumé : Background Domestic violence mechanisms are frequently transmitted across generations, representing a global issue demanding particular attention. This study investigates the intergenerational transmission of intimate partner violence (IPV) and parent-to-child violence (PCV) and whether participating in a multilevel preventive intervention (Fast Track) breaks this transmission. Methods In high-risk elementary schools located in the United States, children considered at high risk for aggressive behavior based on teachers' and parents' screen scores were assigned to either a 10-year intervention or a control group based on their school. The Fast Track trial was registered at clinicaltrials.gov (NCT01653535) and was focused on parenting practices and children's intrapersonal, interpersonal, and academic skills. From the original 891 children, 374 participants with children aged less than 18?years (n?=?191 intervention group, n?=?183 control group) reported at age 34 their experience with domestic violence and their children's psychological adjustment. Results The intergenerational mediating pathway from high IPV in the first generation to high PCV in the second generation to greater total mental health difficulties in the third generation was statistically significant in the control group but not in the intervention group. Conclusions IPV was intergenerationally transmitted by influencing PCV, with a negative effect on the third generation's mental health. Nevertheless, participation in the Fast Track intervention disrupted this cycle. These findings suggest the importance of policies to support preventive childhood interventions. En ligne : https://doi.org/10.1111/jcpp.70133 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591 [article] The randomized controlled trial Fast Track multilevel intervention for children with early-emerging conduct problems breaks intergenerational transmission of violence across three generations [texte imprimé] / Laura GORLA, Auteur ; W. Andrew ROTHENBERG, Auteur ; Jennifer GODWIN, Auteur ; Group CONDUCT PROBLEMS PREVENTION RESEARCH, Auteur . - p.1254-1268. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1254-1268 Mots-clés : intergenerational  intimate partner violence  parent-to-child violence  intervention Index. décimale : PER Périodiques Résumé : Background Domestic violence mechanisms are frequently transmitted across generations, representing a global issue demanding particular attention. This study investigates the intergenerational transmission of intimate partner violence (IPV) and parent-to-child violence (PCV) and whether participating in a multilevel preventive intervention (Fast Track) breaks this transmission. Methods In high-risk elementary schools located in the United States, children considered at high risk for aggressive behavior based on teachers' and parents' screen scores were assigned to either a 10-year intervention or a control group based on their school. The Fast Track trial was registered at clinicaltrials.gov (NCT01653535) and was focused on parenting practices and children's intrapersonal, interpersonal, and academic skills. From the original 891 children, 374 participants with children aged less than 18?years (n?=?191 intervention group, n?=?183 control group) reported at age 34 their experience with domestic violence and their children's psychological adjustment. Results The intergenerational mediating pathway from high IPV in the first generation to high PCV in the second generation to greater total mental health difficulties in the third generation was statistically significant in the control group but not in the intervention group. Conclusions IPV was intergenerationally transmitted by influencing PCV, with a negative effect on the third generation's mental health. Nevertheless, participation in the Fast Track intervention disrupted this cycle. These findings suggest the importance of policies to support preventive childhood interventions. En ligne : https://doi.org/10.1111/jcpp.70133 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591

Indirect genetic effects of siblings / Mathias VALSTAD in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1269-1279 Titre : Indirect genetic effects of siblings Type de document : texte imprimé Auteurs : Mathias VALSTAD, Auteur ; Espen Moen EILERTSEN, Auteur ; Ziada AYORECH, Auteur ; Rosa CHEESMAN, Auteur ; Perline DEMANGE, Auteur ; Nikolai HAAHJEM EFTEDAL, Auteur ; Alexandra HAVDAHL, Auteur ; Eivind YSTROM, Auteur Article en page(s) : p.1269-1279 Langues : Anglais (eng) Mots-clés : ADHD  educational performance  indirect genetic effects  siblings  genome-based maximum likelihood  polygenic indices  MoBa Index. décimale : PER Périodiques Résumé : Background Within-family designs are increasingly used to decompose genotype?trait associations into direct and indirect genetic effects. Many such designs, including trio designs or within-sibship designs, assume an absence of sibling indirect genetic effects. Methods We expand two well-known molecular genetic within-family designs, one variance component (genome-based restricted maximum likelihood) and one trait-based (structural equation modeling with polygenic indices), to estimate sibling indirect genetic effects, along with direct genetic effects. We link the Norwegian Mother, Father, and Child Cohort Study (MoBa) to Norway's national education database to model genetic effects on national standardized testing results at ages 10, 13, and 14, and on parent-rated attention-deficit hyperactivity disorder (ADHD) symptoms at ages 3 and 8 in up to 15,971 genotyped and phenotyped siblings. Results Estimates of direct and indirect genetic effects from the genome-based restricted maximum likelihood and the structural equation modeling with polygenic indices approaches converge, albeit with the variance component estimates typically an order of magnitude greater than the trait-based estimates. We observe no indirect genetic effects of siblings on educational performance at any age, and only slightly negative indirect genetic effects of siblings on ADHD symptoms at age 3. We argue that the latter effect might reflect parental contrasting ratings. Conclusions The results suggest that within-family models of educational performance are unlikely to be drastically biased by an assumption of absent sibling indirect genetic effects. Combining trait-based analyses with variance component analyses can benefit understanding of indirect genetic effects, especially when the effects are not specific to a particular mechanism. En ligne : https://doi.org/10.1111/jcpp.70130 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591 [article] Indirect genetic effects of siblings [texte imprimé] / Mathias VALSTAD, Auteur ; Espen Moen EILERTSEN, Auteur ; Ziada AYORECH, Auteur ; Rosa CHEESMAN, Auteur ; Perline DEMANGE, Auteur ; Nikolai HAAHJEM EFTEDAL, Auteur ; Alexandra HAVDAHL, Auteur ; Eivind YSTROM, Auteur . - p.1269-1279. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1269-1279 Mots-clés : ADHD  educational performance  indirect genetic effects  siblings  genome-based maximum likelihood  polygenic indices  MoBa Index. décimale : PER Périodiques Résumé : Background Within-family designs are increasingly used to decompose genotype?trait associations into direct and indirect genetic effects. Many such designs, including trio designs or within-sibship designs, assume an absence of sibling indirect genetic effects. Methods We expand two well-known molecular genetic within-family designs, one variance component (genome-based restricted maximum likelihood) and one trait-based (structural equation modeling with polygenic indices), to estimate sibling indirect genetic effects, along with direct genetic effects. We link the Norwegian Mother, Father, and Child Cohort Study (MoBa) to Norway's national education database to model genetic effects on national standardized testing results at ages 10, 13, and 14, and on parent-rated attention-deficit hyperactivity disorder (ADHD) symptoms at ages 3 and 8 in up to 15,971 genotyped and phenotyped siblings. Results Estimates of direct and indirect genetic effects from the genome-based restricted maximum likelihood and the structural equation modeling with polygenic indices approaches converge, albeit with the variance component estimates typically an order of magnitude greater than the trait-based estimates. We observe no indirect genetic effects of siblings on educational performance at any age, and only slightly negative indirect genetic effects of siblings on ADHD symptoms at age 3. We argue that the latter effect might reflect parental contrasting ratings. Conclusions The results suggest that within-family models of educational performance are unlikely to be drastically biased by an assumption of absent sibling indirect genetic effects. Combining trait-based analyses with variance component analyses can benefit understanding of indirect genetic effects, especially when the effects are not specific to a particular mechanism. En ligne : https://doi.org/10.1111/jcpp.70130 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591

Parent-led CBT delivered via online and telephone support alongside usual school practice versus usual school practice only for young children identified as at risk for anxiety disorders through screening in schools: a cluster randomised controlled trial / Tessa REARDON in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1280-1296 Titre : Parent-led CBT delivered via online and telephone support alongside usual school practice versus usual school practice only for young children identified as at risk for anxiety disorders through screening in schools: a cluster randomised controlled trial Type de document : texte imprimé Auteurs : Tessa REARDON, Auteur ; Obioha C. UKOUMUNNE, Auteur ; Helen DODD, Auteur ; Gemma HALLIDAY, Auteur ; Claire HILL, Auteur ; Bec JASPER, Auteur ; Benjamin JONES, Auteur ; Peter J. LAWRENCE, Auteur ; Fran MORGAN, Auteur ; Anna PLACZEK, Auteur ; Ronald M. RAPEE, Auteur ; Mara VIOLATO, Auteur ; Shuye YU, Auteur ; Mycats TEAM, Auteur ; Cathy CRESWELL, Auteur Article en page(s) : p.1280-1296 Langues : Anglais (eng) Mots-clés : Anxiety  early intervention  prevention  screening  online intervention  parent-led intervention Index. décimale : PER Périodiques Résumé : Background Providing accessible CBT for young children identified as at risk for anxiety disorders through screening in schools could reduce later problems. This study aimed to evaluate the effectiveness of parent-led CBT delivered via online and telephone call support alongside usual school provision, compared to usual school provision only for young children identified through screening as having at least one risk. Methods We conducted a pragmatic, parallel group, superiority cluster randomised controlled trial in 95 primary/infant schools in England. Parents of children (aged 4?7) in sampled classes completed screening, and children who screened positive for one or more risks (anxiety symptoms/inhibition/parent anxiety) were eligible for the trial. Schools (clusters) were randomised (1:1) to intervention or usual school practice, stratified by school-level deprivation. Schools in both arms continued with usual provision, and parents in intervention schools were offered parent-led CBT via online and telephone support. The primary outcome was the presence of an anxiety disorder diagnosis at 12 months, assessed via the ADIS-P administered by independent assessors. Secondary clinical outcomes included parent-reported child anxiety symptoms, related interference, externalising symptoms, additional risks and intervention targets at 12?weeks and 12 months. Primary analyses were conducted on the full intention-to-treat population. The trial was prospectively registered with ISRCTN 82398107. Results In total, 2,328 children were screened; 1,172 were eligible; 865 enrolled. Forty-eight schools (434 children) were assigned to intervention and 47 schools (431 children) to usual school practice. At 12 months, the overall frequency of anxiety disorders was low, 6.8% (21/310) of children in the intervention arm compared to 11.5% (36/312) in the usual school practice arm; this difference was not statistically significant (adjusted odds ratio 0.67 [0.37 to 1.21], p?=?.19). However, the intervention was superior to usual school practice across all secondary outcomes (standardised mean difference: 0.15 to 0.47 at 12?weeks; 0.19 to 0.41 at 12 months). No serious adverse events were reported. Conclusions Although the intervention did not significantly reduce anxiety disorders at 12 months, improvements across all other assessed outcomes indicate this approach brings wider immediate benefits and reduces known risks for future anxiety disorders. Future research needs to consider longer-term preventative effects. En ligne : https://doi.org/10.1111/jcpp.70119 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591 [article] Parent-led CBT delivered via online and telephone support alongside usual school practice versus usual school practice only for young children identified as at risk for anxiety disorders through screening in schools: a cluster randomised controlled trial [texte imprimé] / Tessa REARDON, Auteur ; Obioha C. UKOUMUNNE, Auteur ; Helen DODD, Auteur ; Gemma HALLIDAY, Auteur ; Claire HILL, Auteur ; Bec JASPER, Auteur ; Benjamin JONES, Auteur ; Peter J. LAWRENCE, Auteur ; Fran MORGAN, Auteur ; Anna PLACZEK, Auteur ; Ronald M. RAPEE, Auteur ; Mara VIOLATO, Auteur ; Shuye YU, Auteur ; Mycats TEAM, Auteur ; Cathy CRESWELL, Auteur . - p.1280-1296. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1280-1296 Mots-clés : Anxiety  early intervention  prevention  screening  online intervention  parent-led intervention Index. décimale : PER Périodiques Résumé : Background Providing accessible CBT for young children identified as at risk for anxiety disorders through screening in schools could reduce later problems. This study aimed to evaluate the effectiveness of parent-led CBT delivered via online and telephone call support alongside usual school provision, compared to usual school provision only for young children identified through screening as having at least one risk. Methods We conducted a pragmatic, parallel group, superiority cluster randomised controlled trial in 95 primary/infant schools in England. Parents of children (aged 4?7) in sampled classes completed screening, and children who screened positive for one or more risks (anxiety symptoms/inhibition/parent anxiety) were eligible for the trial. Schools (clusters) were randomised (1:1) to intervention or usual school practice, stratified by school-level deprivation. Schools in both arms continued with usual provision, and parents in intervention schools were offered parent-led CBT via online and telephone support. The primary outcome was the presence of an anxiety disorder diagnosis at 12 months, assessed via the ADIS-P administered by independent assessors. Secondary clinical outcomes included parent-reported child anxiety symptoms, related interference, externalising symptoms, additional risks and intervention targets at 12?weeks and 12 months. Primary analyses were conducted on the full intention-to-treat population. The trial was prospectively registered with ISRCTN 82398107. Results In total, 2,328 children were screened; 1,172 were eligible; 865 enrolled. Forty-eight schools (434 children) were assigned to intervention and 47 schools (431 children) to usual school practice. At 12 months, the overall frequency of anxiety disorders was low, 6.8% (21/310) of children in the intervention arm compared to 11.5% (36/312) in the usual school practice arm; this difference was not statistically significant (adjusted odds ratio 0.67 [0.37 to 1.21], p?=?.19). However, the intervention was superior to usual school practice across all secondary outcomes (standardised mean difference: 0.15 to 0.47 at 12?weeks; 0.19 to 0.41 at 12 months). No serious adverse events were reported. Conclusions Although the intervention did not significantly reduce anxiety disorders at 12 months, improvements across all other assessed outcomes indicate this approach brings wider immediate benefits and reduces known risks for future anxiety disorders. Future research needs to consider longer-term preventative effects. En ligne : https://doi.org/10.1111/jcpp.70119 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591

Time-dependent association between prenatal hair glucocorticoid levels and child behavior problems / Richard G. KÃœNZEL in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1297-1306 Titre : Time-dependent association between prenatal hair glucocorticoid levels and child behavior problems Type de document : texte imprimé Auteurs : Richard G. KÃœNZEL, Auteur ; Yinxian CHEN, Auteur ; Marta B. RONDON, Auteur ; Diana JUVINAO-QUINTERO, Auteur ; Laramie E. DUNCAN, Auteur ; Sixto E. SANCHEZ, Auteur ; Luz G. NATEROS, Auteur ; Archana BASU, Auteur ; Amantia AMETAJ, Auteur ; Clemens KIRSCHBAUM, Auteur ; Elizabeth J. LEVEY, Auteur ; Bizu GELAYE, Auteur Article en page(s) : p.1297-1306 Langues : Anglais (eng) Mots-clés : Prenatal  hair cortisol  hair cortisone  internalizing  externalizing  behavior  transgenerational Index. décimale : PER Périodiques Résumé : Background Child internalizing and externalizing behavioral problems are highly prevalent psychiatric symptoms worldwide, for which maternal prenatal stress is a known risk factor. However, underlying neuroendocrine mechanisms remain largely unclear. We investigated whether maternal hair cortisol (HCC) and cortisone concentration (HCNC) are associated with offspring's internalizing and externalizing behavior problems in a prospective pre-birth cohort study from Perú. Methods N?=?271 mother?child dyads were included in this analysis. Recruitment and data collection took place at the Instituto Nacional Materno Perinatal in Lima, Perú. HCC and HCHC were obtained from hair segments representing up to 3 months pre-pregnancy and first trimester, respectively, and were quantified via liquid chromatography tandem mass spectrometry. The Child Behavior Checklist was used to assess internalizing and externalizing behavioral problems of children (mean age at follow-up?=?6.98?years (SD?=?1.05)). Marginal structural models estimated population average associations between HCC, HCNC, and internalizing and externalizing problems, adjusting for established covariates. Results At pre-pregnancy, logHCNC was positively associated with offspring internalizing (??=?2.21, 95% CI: 0.46; 3.96, p?=?.013) and externalizing problems (??=?1.87, 95% CI: 0.34; 3.40, p?=?.016). At the first trimester, logHCNC was negatively associated with internalizing (??=??2.51, 95%CI: ?4.37; ?0.64, p?=?.008), and externalizing problems (??=??2.73, 95% CI: ?4.18; ?1.28, p? En ligne : https://doi.org/10.1111/jcpp.70131 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591 [article] Time-dependent association between prenatal hair glucocorticoid levels and child behavior problems [texte imprimé] / Richard G. KÃœNZEL, Auteur ; Yinxian CHEN, Auteur ; Marta B. RONDON, Auteur ; Diana JUVINAO-QUINTERO, Auteur ; Laramie E. DUNCAN, Auteur ; Sixto E. SANCHEZ, Auteur ; Luz G. NATEROS, Auteur ; Archana BASU, Auteur ; Amantia AMETAJ, Auteur ; Clemens KIRSCHBAUM, Auteur ; Elizabeth J. LEVEY, Auteur ; Bizu GELAYE, Auteur . - p.1297-1306. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1297-1306 Mots-clés : Prenatal  hair cortisol  hair cortisone  internalizing  externalizing  behavior  transgenerational Index. décimale : PER Périodiques Résumé : Background Child internalizing and externalizing behavioral problems are highly prevalent psychiatric symptoms worldwide, for which maternal prenatal stress is a known risk factor. However, underlying neuroendocrine mechanisms remain largely unclear. We investigated whether maternal hair cortisol (HCC) and cortisone concentration (HCNC) are associated with offspring's internalizing and externalizing behavior problems in a prospective pre-birth cohort study from Perú. Methods N?=?271 mother?child dyads were included in this analysis. Recruitment and data collection took place at the Instituto Nacional Materno Perinatal in Lima, Perú. HCC and HCHC were obtained from hair segments representing up to 3 months pre-pregnancy and first trimester, respectively, and were quantified via liquid chromatography tandem mass spectrometry. The Child Behavior Checklist was used to assess internalizing and externalizing behavioral problems of children (mean age at follow-up?=?6.98?years (SD?=?1.05)). Marginal structural models estimated population average associations between HCC, HCNC, and internalizing and externalizing problems, adjusting for established covariates. Results At pre-pregnancy, logHCNC was positively associated with offspring internalizing (??=?2.21, 95% CI: 0.46; 3.96, p?=?.013) and externalizing problems (??=?1.87, 95% CI: 0.34; 3.40, p?=?.016). At the first trimester, logHCNC was negatively associated with internalizing (??=??2.51, 95%CI: ?4.37; ?0.64, p?=?.008), and externalizing problems (??=??2.73, 95% CI: ?4.18; ?1.28, p? En ligne : https://doi.org/10.1111/jcpp.70131 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591

Outcome and cost-effectiveness of transdiagnostic cognitive behavioral therapy compared with management as usual for youth with common mental health problems: Long-term results from the Mind-My-Mind randomized trial / Ditte VASSARD in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1307-1320 Titre : Outcome and cost-effectiveness of transdiagnostic cognitive behavioral therapy compared with management as usual for youth with common mental health problems: Long-term results from the Mind-My-Mind randomized trial Type de document : texte imprimé Auteurs : Ditte VASSARD, Auteur ; Martin Køster RIMVALL, Auteur ; Rasmus Trap WOLF, Auteur ; Robin CHRISTENSEN, Auteur ; Sabrina M. NIELSEN, Auteur ; Kerstin Jessica PLESSEN, Auteur ; Frank VERHULST, Auteur ; Niels BILENBERG, Auteur ; Per Hove THOMSEN, Auteur ; Mikael THASTUM, Auteur ; Simon-Peter NEUMER, Auteur ; Anne Katrine PAGSBERG, Auteur ; Wendy K. SILVERMAN, Auteur ; Christoph U. CORRELL, Auteur ; Pia JEPPESEN, Auteur Article en page(s) : p.1307-1320 Langues : Anglais (eng) Mots-clés : Cognitive behavioral therapy  mental health problems  school-based  children and adolescents Index. décimale : PER Périodiques Résumé : Background Credible long-term outcomes from randomized trials evaluating the effectiveness and cost-effectiveness of preventive programs for mental health problems are needed. We compared long-term effects of the Mind My Mind (MMM) transdiagnostic cognitive behavioral therapy (CBT) program to management as usual (MAU). Methods The study was a pragmatic, multisite, randomized superiority trial (2017?2019) involving youths aged 6?16?years with anxiety, depressive symptoms, and/or behavioral disturbances, recruited through family self-referral. The MMM intervention included 9?13 weekly CBT sessions. The primary outcome was change from baseline in parent-reported impact of mental health problems at 3-year follow-up post-randomization using the Strengths and Difficulties Questionnaire (SDQ) impact scale. Register-based outcomes tracked youths' psychiatric diagnoses in mental health services. To assess cost-effectiveness, we calculated the incremental costs and incremental quality-adjusted life years (QALYs). All primary analyses followed the intention-to-treat (ITT) approach. Clinical trials registration: ID NCT04804917. Results Among 396 youths randomized (baseline mean [SD] age, 10.3?[2.4] years; 52.0% boys; MMM n?=?197, MAU n?=?199), the 3-year follow-up (median 167?weeks; range 124?203?weeks) primary outcome data were available in 69.0% and 59.3%, respectively. The decrease in SDQ-impact-score from baseline to 3-year follow-up (4.12?1.79 points [MMM] and 4.21?1.85 [MAU]) was similar (between-group difference, 0.06 [95% CI ?0.41 to 0.52]; p?=?.81). An equal proportion (25%) of youths in MMM and MAU were diagnosed with any mental disorder during follow-up (HR 1.01, 95% CI 0.68?1.50). Total costs over the intervention period were higher in the MMM group (incremental costs 3,014 Euros [95% CI: 2.174?3.855]). Cost-effectiveness analyses favored MMM: QALY net gain 0.121 (95% CI 0.045?0.196); the cost-effectiveness ratio was 24,789 Euro/QALY. Conclusions Although MMM was potentially cost-effective, the beneficial effects diminished over 3?years post-treatment. The findings highlight the need for strategies to sustain long-term effects. En ligne : https://doi.org/10.1111/jcpp.70128 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591 [article] Outcome and cost-effectiveness of transdiagnostic cognitive behavioral therapy compared with management as usual for youth with common mental health problems: Long-term results from the Mind-My-Mind randomized trial [texte imprimé] / Ditte VASSARD, Auteur ; Martin Køster RIMVALL, Auteur ; Rasmus Trap WOLF, Auteur ; Robin CHRISTENSEN, Auteur ; Sabrina M. NIELSEN, Auteur ; Kerstin Jessica PLESSEN, Auteur ; Frank VERHULST, Auteur ; Niels BILENBERG, Auteur ; Per Hove THOMSEN, Auteur ; Mikael THASTUM, Auteur ; Simon-Peter NEUMER, Auteur ; Anne Katrine PAGSBERG, Auteur ; Wendy K. SILVERMAN, Auteur ; Christoph U. CORRELL, Auteur ; Pia JEPPESEN, Auteur . - p.1307-1320. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1307-1320 Mots-clés : Cognitive behavioral therapy  mental health problems  school-based  children and adolescents Index. décimale : PER Périodiques Résumé : Background Credible long-term outcomes from randomized trials evaluating the effectiveness and cost-effectiveness of preventive programs for mental health problems are needed. We compared long-term effects of the Mind My Mind (MMM) transdiagnostic cognitive behavioral therapy (CBT) program to management as usual (MAU). Methods The study was a pragmatic, multisite, randomized superiority trial (2017?2019) involving youths aged 6?16?years with anxiety, depressive symptoms, and/or behavioral disturbances, recruited through family self-referral. The MMM intervention included 9?13 weekly CBT sessions. The primary outcome was change from baseline in parent-reported impact of mental health problems at 3-year follow-up post-randomization using the Strengths and Difficulties Questionnaire (SDQ) impact scale. Register-based outcomes tracked youths' psychiatric diagnoses in mental health services. To assess cost-effectiveness, we calculated the incremental costs and incremental quality-adjusted life years (QALYs). All primary analyses followed the intention-to-treat (ITT) approach. Clinical trials registration: ID NCT04804917. Results Among 396 youths randomized (baseline mean [SD] age, 10.3?[2.4] years; 52.0% boys; MMM n?=?197, MAU n?=?199), the 3-year follow-up (median 167?weeks; range 124?203?weeks) primary outcome data were available in 69.0% and 59.3%, respectively. The decrease in SDQ-impact-score from baseline to 3-year follow-up (4.12?1.79 points [MMM] and 4.21?1.85 [MAU]) was similar (between-group difference, 0.06 [95% CI ?0.41 to 0.52]; p?=?.81). An equal proportion (25%) of youths in MMM and MAU were diagnosed with any mental disorder during follow-up (HR 1.01, 95% CI 0.68?1.50). Total costs over the intervention period were higher in the MMM group (incremental costs 3,014 Euros [95% CI: 2.174?3.855]). Cost-effectiveness analyses favored MMM: QALY net gain 0.121 (95% CI 0.045?0.196); the cost-effectiveness ratio was 24,789 Euro/QALY. Conclusions Although MMM was potentially cost-effective, the beneficial effects diminished over 3?years post-treatment. The findings highlight the need for strategies to sustain long-term effects. En ligne : https://doi.org/10.1111/jcpp.70128 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591

Changes in idiographic coping in youth treated for an anxiety disorder / Marisa MEYER in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1321-1334 Titre : Changes in idiographic coping in youth treated for an anxiety disorder Type de document : texte imprimé Auteurs : Marisa MEYER, Auteur ; Thomas M. OLINO, Auteur ; Anne Marie ALBANO, Auteur ; John C. PIACENTINI, Auteur ; Scott N. COMPTON, Auteur ; Elizabeth A. GOSCH, Auteur ; Philip C. KENDALL, Auteur Article en page(s) : p.1321-1334 Langues : Anglais (eng) Mots-clés : anxiety  coping  idiographic assessment Index. décimale : PER Périodiques Résumé : Background Youth anxiety disorders are highly prevalent and associated with adverse outcomes. Prior research demonstrated improvement in anxiety symptoms following evidence-based treatment; however, not all youth experience symptom remission, nor do they consistently maintain gains. We examined idiographic changes in youths' perceived ability to cope with individualized anxiety-provoking situations from pretreatment to six-month follow-up in the Child/Adolescent Anxiety Multimodal Treatment Study. Methods Youth diagnosed with a principal anxiety disorder (N?=?488; ages 7?17; 50.4% male) were randomized to cognitive-behavioral therapy (CBT), pharmacotherapy (SRT), combination of CBT and SRT, or pill placebo. Youth's perceived ability to cope (i.e., perceived coping efficacy) was assessed independently using youth self-reports and caregiver-reports on the Coping Questionnaire, an idiographic measure with anxiety-provoking situations individualized to each youth. Changes in perceived coping efficacy were examined across treatment conditions using multilevel models, assessed across six timepoints. Models estimating the quadratic effect of time fit better than models estimating the linear effect. Results There was a significant interaction between the quadratic effect of time and treatment condition, indicating perceptions of youth coping efficacy increase from pretreatment to six-month follow-up, yet at different times across treatment based on treatment condition; this finding was observed per both youth- and caregiver-reports. Perceptions of coping efficacy did not differ based on treatment condition for either informant at pretreatment or six-month follow-up; however, post hoc analyses revealed significant differences in perceptions of youth coping efficacy at all interim assessments. Conclusions Results demonstrate that effective treatments for youth anxiety disorders improved youth- and caregiver-reports of perceived coping with youths' individualized anxiety-provoking situations. Future efforts could prioritize idiographic assessments to facilitate effective treatments. En ligne : https://doi.org/10.1111/jcpp.70139 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591 [article] Changes in idiographic coping in youth treated for an anxiety disorder [texte imprimé] / Marisa MEYER, Auteur ; Thomas M. OLINO, Auteur ; Anne Marie ALBANO, Auteur ; John C. PIACENTINI, Auteur ; Scott N. COMPTON, Auteur ; Elizabeth A. GOSCH, Auteur ; Philip C. KENDALL, Auteur . - p.1321-1334. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1321-1334 Mots-clés : anxiety  coping  idiographic assessment Index. décimale : PER Périodiques Résumé : Background Youth anxiety disorders are highly prevalent and associated with adverse outcomes. Prior research demonstrated improvement in anxiety symptoms following evidence-based treatment; however, not all youth experience symptom remission, nor do they consistently maintain gains. We examined idiographic changes in youths' perceived ability to cope with individualized anxiety-provoking situations from pretreatment to six-month follow-up in the Child/Adolescent Anxiety Multimodal Treatment Study. Methods Youth diagnosed with a principal anxiety disorder (N?=?488; ages 7?17; 50.4% male) were randomized to cognitive-behavioral therapy (CBT), pharmacotherapy (SRT), combination of CBT and SRT, or pill placebo. Youth's perceived ability to cope (i.e., perceived coping efficacy) was assessed independently using youth self-reports and caregiver-reports on the Coping Questionnaire, an idiographic measure with anxiety-provoking situations individualized to each youth. Changes in perceived coping efficacy were examined across treatment conditions using multilevel models, assessed across six timepoints. Models estimating the quadratic effect of time fit better than models estimating the linear effect. Results There was a significant interaction between the quadratic effect of time and treatment condition, indicating perceptions of youth coping efficacy increase from pretreatment to six-month follow-up, yet at different times across treatment based on treatment condition; this finding was observed per both youth- and caregiver-reports. Perceptions of coping efficacy did not differ based on treatment condition for either informant at pretreatment or six-month follow-up; however, post hoc analyses revealed significant differences in perceptions of youth coping efficacy at all interim assessments. Conclusions Results demonstrate that effective treatments for youth anxiety disorders improved youth- and caregiver-reports of perceived coping with youths' individualized anxiety-provoking situations. Future efforts could prioritize idiographic assessments to facilitate effective treatments. En ligne : https://doi.org/10.1111/jcpp.70139 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591

Away from violence: A latent transition analysis on support for violent and non-violent radicalization among adolescents / Diana MICONI in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1335-1347 Titre : Away from violence: A latent transition analysis on support for violent and non-violent radicalization among adolescents Type de document : texte imprimé Auteurs : Diana MICONI, Auteur ; Michela ZAMBELLI, Auteur ; Aoudou Njingouo MOUNCHINGAM, Auteur ; Cécile ROUSSEAU, Auteur Article en page(s) : p.1335-1347 Langues : Anglais (eng) Mots-clés : Radicalization  violence  adolescence  activism  ideologies Index. décimale : PER Périodiques Résumé : Background Support for violent and non-violent radicalization co-exists in some, but not all, adolescents. Yet, little is known about how adolescents transition towards or away from violent and/or non-violent radicalization over time. Within a socio-ecological framework, this study investigates how Canadian adolescents move from profiles that support violent radicalization to non-violent profiles and vice-versa and whether profile belonging is associated with social-, school- and family-related factors, psychological distress and specific ideologies. Methods High school students (N?=?574; Mage?=?15.1; SDage?=?0.76; 47.7% girls) completed an online survey in 2023 and 2024. A latent transition analysis on scores of support for violent and non-violent radicalization was conducted. Multinomial regression was used to explore the associations between profiles and variables of interest. Results Adolescents moved significantly across the six identified profiles over time. School unsafety was associated with an increased probability of being in more violent profiles, whereas depressive symptoms were lower in disengaged and violent profiles. Glorification of violence was higher in the more violent and less activist profile. Adolescents reporting more distress related to international conflicts and pro-environmental ideologies were more likely to belong to more activist profiles, including those supportive of violence. Conclusions Exploration of activism and violence as idioms of protest is common during adolescence and youth's attitudes in this regard are very dynamic, influenced by local and global grievances. Primary prevention efforts should accompany youth in their exploration in order to support non-violent avenues as responses to global conflicts, as well as daily injustices. En ligne : https://doi.org/10.1111/jcpp.70142 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591 [article] Away from violence: A latent transition analysis on support for violent and non-violent radicalization among adolescents [texte imprimé] / Diana MICONI, Auteur ; Michela ZAMBELLI, Auteur ; Aoudou Njingouo MOUNCHINGAM, Auteur ; Cécile ROUSSEAU, Auteur . - p.1335-1347. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1335-1347 Mots-clés : Radicalization  violence  adolescence  activism  ideologies Index. décimale : PER Périodiques Résumé : Background Support for violent and non-violent radicalization co-exists in some, but not all, adolescents. Yet, little is known about how adolescents transition towards or away from violent and/or non-violent radicalization over time. Within a socio-ecological framework, this study investigates how Canadian adolescents move from profiles that support violent radicalization to non-violent profiles and vice-versa and whether profile belonging is associated with social-, school- and family-related factors, psychological distress and specific ideologies. Methods High school students (N?=?574; Mage?=?15.1; SDage?=?0.76; 47.7% girls) completed an online survey in 2023 and 2024. A latent transition analysis on scores of support for violent and non-violent radicalization was conducted. Multinomial regression was used to explore the associations between profiles and variables of interest. Results Adolescents moved significantly across the six identified profiles over time. School unsafety was associated with an increased probability of being in more violent profiles, whereas depressive symptoms were lower in disengaged and violent profiles. Glorification of violence was higher in the more violent and less activist profile. Adolescents reporting more distress related to international conflicts and pro-environmental ideologies were more likely to belong to more activist profiles, including those supportive of violence. Conclusions Exploration of activism and violence as idioms of protest is common during adolescence and youth's attitudes in this regard are very dynamic, influenced by local and global grievances. Primary prevention efforts should accompany youth in their exploration in order to support non-violent avenues as responses to global conflicts, as well as daily injustices. En ligne : https://doi.org/10.1111/jcpp.70142 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591

Reward-network connectivity in childhood predicts multi-domain dysregulation in adolescence / Eugenia GIAMPETRUZZI in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1348-1360 Titre : Reward-network connectivity in childhood predicts multi-domain dysregulation in adolescence Type de document : texte imprimé Auteurs : Eugenia GIAMPETRUZZI, Auteur ; Parmis KHOSRAVI, Auteur ; Katharina KIRCANSKI, Auteur ; Chase ANTONACCI, Auteur ; Daniel S. PINE, Auteur ; Ian H. GOTLIB, Auteur Article en page(s) : p.1348-1360 Langues : Anglais (eng) Mots-clés : Dysregulation profile  reward network connectivity  adolescence Index. décimale : PER Périodiques Résumé : Background Multi-domain dysregulation in adolescence, indexed by co-occurring affective, cognitive, and behavioural difficulties, is a robust transdiagnostic risk factor. However, its developmental course and neural antecedents are poorly understood. Given heightened emotional reactivity and impulsivity in adolescence, alterations in reward-network connectivity may represent an early neural marker of risk. Methods Adolescents completed four assessments approximately two years apart between ages 9?13 and 15?18?years. Multi-domain dysregulation was assessed at each wave using the Youth Self-Report Dysregulation Profile (YSR-DP), computed as the sum of the anxious/depressed, aggressive behaviour, and attention problems subscales. Resting-state fMRI was acquired at baseline (Mage?=?11.34?years). Piecewise linear mixed-effects models (N?=?211) characterized trajectories of YSR-DP scores across adolescence. Principal component scores indexing a Latent Dysregulation Factor were used to derive residualised change in dysregulation, and regression analyses (N?=?94) tested whether baseline reward-network connectivity predicted this change. Results YSR-DP scores declined from late childhood to early adolescence, increased from early to mid-adolescence, and then stabilized in late adolescence. Weaker connectivity within the reward network in late childhood predicted greater increases in the latent dysregulation factor from early to mid-adolescence, above and beyond baseline dysregulation. Connectivity in seven large-scale control networks did not predict changes in dysregulation. Conclusions Multi-domain dysregulation follows a nonlinear trajectory across adolescence, and weaker reward-network connectivity in childhood prospectively predicts subsequent escalation of this phenotype. Prevention and intervention efforts may benefit from targeting reward processing and regulatory skills in late childhood and early adolescence. En ligne : https://doi.org/10.1111/jcpp.70143 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591 [article] Reward-network connectivity in childhood predicts multi-domain dysregulation in adolescence [texte imprimé] / Eugenia GIAMPETRUZZI, Auteur ; Parmis KHOSRAVI, Auteur ; Katharina KIRCANSKI, Auteur ; Chase ANTONACCI, Auteur ; Daniel S. PINE, Auteur ; Ian H. GOTLIB, Auteur . - p.1348-1360. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1348-1360 Mots-clés : Dysregulation profile  reward network connectivity  adolescence Index. décimale : PER Périodiques Résumé : Background Multi-domain dysregulation in adolescence, indexed by co-occurring affective, cognitive, and behavioural difficulties, is a robust transdiagnostic risk factor. However, its developmental course and neural antecedents are poorly understood. Given heightened emotional reactivity and impulsivity in adolescence, alterations in reward-network connectivity may represent an early neural marker of risk. Methods Adolescents completed four assessments approximately two years apart between ages 9?13 and 15?18?years. Multi-domain dysregulation was assessed at each wave using the Youth Self-Report Dysregulation Profile (YSR-DP), computed as the sum of the anxious/depressed, aggressive behaviour, and attention problems subscales. Resting-state fMRI was acquired at baseline (Mage?=?11.34?years). Piecewise linear mixed-effects models (N?=?211) characterized trajectories of YSR-DP scores across adolescence. Principal component scores indexing a Latent Dysregulation Factor were used to derive residualised change in dysregulation, and regression analyses (N?=?94) tested whether baseline reward-network connectivity predicted this change. Results YSR-DP scores declined from late childhood to early adolescence, increased from early to mid-adolescence, and then stabilized in late adolescence. Weaker connectivity within the reward network in late childhood predicted greater increases in the latent dysregulation factor from early to mid-adolescence, above and beyond baseline dysregulation. Connectivity in seven large-scale control networks did not predict changes in dysregulation. Conclusions Multi-domain dysregulation follows a nonlinear trajectory across adolescence, and weaker reward-network connectivity in childhood prospectively predicts subsequent escalation of this phenotype. Prevention and intervention efforts may benefit from targeting reward processing and regulatory skills in late childhood and early adolescence. En ligne : https://doi.org/10.1111/jcpp.70143 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591

Directionality of longitudinal associations between frontostriatal structural connectivity and depressive symptoms in adolescent girls / Marjolein E. A. BARENDSE in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1361-1370 Titre : Directionality of longitudinal associations between frontostriatal structural connectivity and depressive symptoms in adolescent girls Type de document : texte imprimé Auteurs : Marjolein E. A. BARENDSE, Auteur ; Chris J. MACHLE, Auteur ; Rogier KIEVIT, Auteur ; Jennifer H. PFEIFER, Auteur Article en page(s) : p.1361-1370 Langues : Anglais (eng) Mots-clés : Reward  white matter  depression  puberty  age Index. décimale : PER Périodiques Résumé : Background Individual differences in the structure and function of the frontostriatal reward network have been related to depression. However, there is a strong need for prospective, longitudinal studies aiming to understand the role of frontostriatal networks in depression in a developmental context. We aimed to examine bidirectional associations between structural connectivity in the frontostriatal reward network and depressive symptoms in adolescent girls, as well as to determine to what extent the directionality and strength of these associations are dependent on age or pubertal stage. Methods About 596 observations from 174 adolescent girls (up to 4 time points per person, ages 10?17) were included. Depressive symptoms were measured with the Center for Epidemiological Studies-Depression scale for Children and pubertal stage with the Pubertal Development Scale and the Tanner Stage Line Drawings. Probabilistic tractography was done on diffusion-weighted imaging scans to obtain average fractional anisotropy from ventral striatum to orbitofrontal cortex and ventral striatum to ventromedial prefrontal cortex tracts. Results Linear mixed-effects models showed that frontostriatal connectivity was not associated with subsequent change in depressive symptoms. Depressive symptoms were also not associated with subsequent change in frontostriatal connectivity. Depressive symptoms increased with age and pubertal stage, but the association with connectivity did not vary with age or pubertal stage. Conclusions This suggests previously reported cross-sectional associations might not pertain to developmental effects in girls. Future research should examine prospective associations between frontostriatal functional connectivity and depression. En ligne : https://doi.org/10.1111/jcpp.70127 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591 [article] Directionality of longitudinal associations between frontostriatal structural connectivity and depressive symptoms in adolescent girls [texte imprimé] / Marjolein E. A. BARENDSE, Auteur ; Chris J. MACHLE, Auteur ; Rogier KIEVIT, Auteur ; Jennifer H. PFEIFER, Auteur . - p.1361-1370. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1361-1370 Mots-clés : Reward  white matter  depression  puberty  age Index. décimale : PER Périodiques Résumé : Background Individual differences in the structure and function of the frontostriatal reward network have been related to depression. However, there is a strong need for prospective, longitudinal studies aiming to understand the role of frontostriatal networks in depression in a developmental context. We aimed to examine bidirectional associations between structural connectivity in the frontostriatal reward network and depressive symptoms in adolescent girls, as well as to determine to what extent the directionality and strength of these associations are dependent on age or pubertal stage. Methods About 596 observations from 174 adolescent girls (up to 4 time points per person, ages 10?17) were included. Depressive symptoms were measured with the Center for Epidemiological Studies-Depression scale for Children and pubertal stage with the Pubertal Development Scale and the Tanner Stage Line Drawings. Probabilistic tractography was done on diffusion-weighted imaging scans to obtain average fractional anisotropy from ventral striatum to orbitofrontal cortex and ventral striatum to ventromedial prefrontal cortex tracts. Results Linear mixed-effects models showed that frontostriatal connectivity was not associated with subsequent change in depressive symptoms. Depressive symptoms were also not associated with subsequent change in frontostriatal connectivity. Depressive symptoms increased with age and pubertal stage, but the association with connectivity did not vary with age or pubertal stage. Conclusions This suggests previously reported cross-sectional associations might not pertain to developmental effects in girls. Future research should examine prospective associations between frontostriatal functional connectivity and depression. En ligne : https://doi.org/10.1111/jcpp.70127 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591

Children's oppositional defiant disorder and mother–child interpersonal brain synchrony: the role of maternal meta-emotion philosophy / Peizhong WANG in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1371-1382 Titre : Children's oppositional defiant disorder and mother–child interpersonal brain synchrony: the role of maternal meta-emotion philosophy Type de document : texte imprimé Auteurs : Peizhong WANG, Auteur ; Jingwei MA, Auteur ; Lu QIAO, Auteur ; Ting HE, Auteur ; Jintao ZHANG, Auteur ; Xiuyun LIN, Auteur Article en page(s) : p.1371-1382 Langues : Anglais (eng) Mots-clés : Oppositional defiant disorder  interpersonal brain synchrony  maternal meta-emotion philosophy  fNIRS Index. décimale : PER Périodiques Résumé : Background Parent?child interpersonal brain synchrony (IBS) has been suggested to play an important role in children's socio-emotional functioning and may be relevant to oppositional defiant disorder (ODD). Yet, empirical evidence regarding IBS deficits between parents and ODD children remains limited, as well as their association with ODD symptoms within different emotional parenting contexts. Therefore, the present study investigated the IBS among mother?child dyads by utilizing functional near-infrared spectroscopy (fNIRS) and the moderating role of maternal meta-emotion philosophy between IBS and ODD symptoms. Methods We initially recruited 72 mother?child dyads and included data from 63 dyads in the final analyses after data quality checks, including 29 ODD children and 34 typically developing (TD) children. Each dyad was measured for IBS while completing a computer-based game, including cooperative and independent conditions. The children's ODD symptoms and maternal meta-emotion philosophy were measured using questionnaires. Results The IBS deficits of left postcentral gyrusm-left dorsal superior frontal gyrusc, left middle frontal gyrusm-right postcentral gyrusc, and right angular gyrusm-right dorsal superior frontal gyrusc were revealed among ODD mother?child dyads across multiple time-lags. In addition, IBS negatively predicted ODD symptoms when mothers were involved in their children's emotions and positively predicted ODD symptoms when mothers were not involved in their children's emotions. Conclusions These findings suggested a potential ?Other-(Social) Cognition?Self-Regulation? IBS network, wherein ?Other-Cognition? involves social cognitive processing of information from others, and ?Self-Regulation? consists of the regulation of oneself. Furthermore, the deficits within this IBS network among ODD mother?child dyads are prospectively predictive of children's later ODD symptoms. Additionally, our research indicated that whether the mother is involved in the child's emotions is crucial when considering the impact of IBS on the development of ODD symptoms. En ligne : https://doi.org/10.1111/jcpp.70137 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591 [article] Children's oppositional defiant disorder and mother–child interpersonal brain synchrony: the role of maternal meta-emotion philosophy [texte imprimé] / Peizhong WANG, Auteur ; Jingwei MA, Auteur ; Lu QIAO, Auteur ; Ting HE, Auteur ; Jintao ZHANG, Auteur ; Xiuyun LIN, Auteur . - p.1371-1382. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1371-1382 Mots-clés : Oppositional defiant disorder  interpersonal brain synchrony  maternal meta-emotion philosophy  fNIRS Index. décimale : PER Périodiques Résumé : Background Parent?child interpersonal brain synchrony (IBS) has been suggested to play an important role in children's socio-emotional functioning and may be relevant to oppositional defiant disorder (ODD). Yet, empirical evidence regarding IBS deficits between parents and ODD children remains limited, as well as their association with ODD symptoms within different emotional parenting contexts. Therefore, the present study investigated the IBS among mother?child dyads by utilizing functional near-infrared spectroscopy (fNIRS) and the moderating role of maternal meta-emotion philosophy between IBS and ODD symptoms. Methods We initially recruited 72 mother?child dyads and included data from 63 dyads in the final analyses after data quality checks, including 29 ODD children and 34 typically developing (TD) children. Each dyad was measured for IBS while completing a computer-based game, including cooperative and independent conditions. The children's ODD symptoms and maternal meta-emotion philosophy were measured using questionnaires. Results The IBS deficits of left postcentral gyrusm-left dorsal superior frontal gyrusc, left middle frontal gyrusm-right postcentral gyrusc, and right angular gyrusm-right dorsal superior frontal gyrusc were revealed among ODD mother?child dyads across multiple time-lags. In addition, IBS negatively predicted ODD symptoms when mothers were involved in their children's emotions and positively predicted ODD symptoms when mothers were not involved in their children's emotions. Conclusions These findings suggested a potential ?Other-(Social) Cognition?Self-Regulation? IBS network, wherein ?Other-Cognition? involves social cognitive processing of information from others, and ?Self-Regulation? consists of the regulation of oneself. Furthermore, the deficits within this IBS network among ODD mother?child dyads are prospectively predictive of children's later ODD symptoms. Additionally, our research indicated that whether the mother is involved in the child's emotions is crucial when considering the impact of IBS on the development of ODD symptoms. En ligne : https://doi.org/10.1111/jcpp.70137 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591

Violent and sexual victimisation and incident anxiety, mood and substance use disorders in childhood and adolescence: a co-sibling study / Joonas PITKÄNEN in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1383-1392 Titre : Violent and sexual victimisation and incident anxiety, mood and substance use disorders in childhood and adolescence: a co-sibling study Type de document : texte imprimé Auteurs : Joonas PITKÄNEN, Auteur ; Amir SARIASLAN, Auteur ; Lauren BISHOP, Auteur ; Mikko AALTONEN, Auteur ; Laura MIELITYINEN, Auteur ; Taina LAAJASALO, Auteur ; Noora ELLONEN, Auteur ; Pekka MARTIKAINEN, Auteur Article en page(s) : p.1383-1392 Langues : Anglais (eng) Mots-clés : Violent victimisation  sexual victimisation  mood disorders  anxiety disorders  substance use disorders  sibling comparison Index. décimale : PER Périodiques Résumé : Background Studies on the association between victimisation in childhood and adolescence and psychiatric disorders increasingly acknowledge that these associations might be partly confounded by unmeasured familial factors. However, previous quasi-experimental evidence is largely based on retrospective self-reported data with potential response biases and small samples. Methods We measured psychiatric disorders and victimisation events from routinely collected administrative datasets on Finnish total birth cohorts 1996?2005. We identified all violent and sexual victimisation events using plaintiff information taken from registers containing data on crimes reported to the police between birth and the end of 2020. Incident anxiety, mood and substance use disorders were identified from registers containing records of inpatient and specialised outpatient psychiatric care. We compared all those exposed to victimisation to five population controls and their unexposed siblings, with the latter thereby adjusting for shared unobserved familial factors. We used stratified Cox regression models to estimate the associations between victimisation and the psychiatric disorders, with a follow-up from victimisation until the outcome, exit from the population or the end of 2020. Results Violent and sexual police-reported victimisation were both associated with an increased risk of psychiatric disorders, with adjusted hazard ratios ranging between 2.3 (95% Confidence Interval [CI]: 2.2, 2.4) for the association between violent victimisation and mood disorders and 3.9 (3.7, 4.1) for the association between sexual victimisation and anxiety disorders. In the sibling comparisons, the associations attenuated but remained clearly elevated, with the corresponding hazard ratios ranging between 1.9 (1.7, 2.1) and 2.6 (2.3, 2.9). Conclusions The results are consistent with a causal interpretation of the association between police-reported victimisation and psychiatric disorders. Mental health-related support after victimisation is an important task as it may prevent the onset of psychiatric disorders. Prevention of victimisation might decrease the number of psychiatric disorders in the population. En ligne : https://doi.org/10.1111/jcpp.70144 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591 [article] Violent and sexual victimisation and incident anxiety, mood and substance use disorders in childhood and adolescence: a co-sibling study [texte imprimé] / Joonas PITKÄNEN, Auteur ; Amir SARIASLAN, Auteur ; Lauren BISHOP, Auteur ; Mikko AALTONEN, Auteur ; Laura MIELITYINEN, Auteur ; Taina LAAJASALO, Auteur ; Noora ELLONEN, Auteur ; Pekka MARTIKAINEN, Auteur . - p.1383-1392. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1383-1392 Mots-clés : Violent victimisation  sexual victimisation  mood disorders  anxiety disorders  substance use disorders  sibling comparison Index. décimale : PER Périodiques Résumé : Background Studies on the association between victimisation in childhood and adolescence and psychiatric disorders increasingly acknowledge that these associations might be partly confounded by unmeasured familial factors. However, previous quasi-experimental evidence is largely based on retrospective self-reported data with potential response biases and small samples. Methods We measured psychiatric disorders and victimisation events from routinely collected administrative datasets on Finnish total birth cohorts 1996?2005. We identified all violent and sexual victimisation events using plaintiff information taken from registers containing data on crimes reported to the police between birth and the end of 2020. Incident anxiety, mood and substance use disorders were identified from registers containing records of inpatient and specialised outpatient psychiatric care. We compared all those exposed to victimisation to five population controls and their unexposed siblings, with the latter thereby adjusting for shared unobserved familial factors. We used stratified Cox regression models to estimate the associations between victimisation and the psychiatric disorders, with a follow-up from victimisation until the outcome, exit from the population or the end of 2020. Results Violent and sexual police-reported victimisation were both associated with an increased risk of psychiatric disorders, with adjusted hazard ratios ranging between 2.3 (95% Confidence Interval [CI]: 2.2, 2.4) for the association between violent victimisation and mood disorders and 3.9 (3.7, 4.1) for the association between sexual victimisation and anxiety disorders. In the sibling comparisons, the associations attenuated but remained clearly elevated, with the corresponding hazard ratios ranging between 1.9 (1.7, 2.1) and 2.6 (2.3, 2.9). Conclusions The results are consistent with a causal interpretation of the association between police-reported victimisation and psychiatric disorders. Mental health-related support after victimisation is an important task as it may prevent the onset of psychiatric disorders. Prevention of victimisation might decrease the number of psychiatric disorders in the population. En ligne : https://doi.org/10.1111/jcpp.70144 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=591

Effectiveness of the school-based internet intervention StresSOS for the prevention of mental health problems in young people: a randomized controlled trial as part of the ProHEAD consortium / Laya LEHNER in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1393-1403 Titre : Effectiveness of the school-based internet intervention StresSOS for the prevention of mental health problems in young people: a randomized controlled trial as part of the ProHEAD consortium Type de document : texte imprimé Auteurs : Laya LEHNER, Auteur ; Vera GILLÉ, Auteur ; Markus MOESSNER, Auteur ; Sabrina BALDOFSKI, Auteur ; Stephanie BAUER, Auteur ; Katja BECKER, Auteur ; Silke DIESTELKAMP, Auteur ; Alisa HIERY, Auteur ; Michael KAESS, Auteur ; Julian KOENIG, Auteur ; Sophia LUSTIG, Auteur ; Christine RUMMEL-KLUGE, Auteur ; Rainer THOMASIUS, Auteur ; Heike ESCHENBECK, Auteur ; Head Consortium THE PRO, Auteur Article en page(s) : p.1393-1403 Langues : Anglais (eng) Mots-clés : Online  internet  prevention  intervention  adolescents  young people  mental health  mental illness Index. décimale : PER Périodiques Résumé : Background Given the high prevalence of mental illnesses in adolescents, there is an urgent need for effective prevention strategies. The aim of this study was to evaluate the school-based internet intervention StresSOS for the universal prevention of mental illnesses in youth. Methods A two-arm, randomized controlled trial was conducted. Participants were recruited from schools across five regions of Germany. Young people between the ages of 12 and 25?years without mental health problems were invited to the trial and randomly assigned to StresSOS or to the attention placebo control condition, stratified by sex. Participants in both conditions received eight web-based sessions with information and exercises and weekly e-mail teasers about program content and a monitoring survey. StresSOS comprised content on life skills, particularly stress management and mental health literacy, and the control condition content comprised healthy nutrition. The primary outcome was self-reported mental health status at a 12-month follow-up. Intention-to-treat analyses were calculated. The trial was preregistered with the German Register of Clinical Trials (DRKS00014693, see https://drks.de/search/en/trial/DRKS00014693). Results A total of 5,268 eligible students were invited to participate, 2,327 (44%) activated their account and were randomized to StresSOS (n?=?1,154) or to the control condition (n?=?1,173). Due to COVID-19-related school closures, 1,209 were lost to follow-up, and data from 1,118 students were analyzed (535 in StresSOS and 583 in the control group). Participation in StresSOS led to significantly reduced incidences of emerging mental health problems at the 12-month follow-up (controls: n?=?162 [28%] ?with problems?; StresSOS: n?=?113 [21%] ?with problems?; OR 0.70, 95% CI [0.52, 0.92], p?=?.01). Conclusions StresSOS was effective in universally preventing the onset of mental health problems, with a small effect. Internet interventions have the potential to contribute to a reduction of the disease burden in young people. En ligne : https://doi.org/10.1111/jcpp.70145 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=592 [article] Effectiveness of the school-based internet intervention StresSOS for the prevention of mental health problems in young people: a randomized controlled trial as part of the ProHEAD consortium [texte imprimé] / Laya LEHNER, Auteur ; Vera GILLÉ, Auteur ; Markus MOESSNER, Auteur ; Sabrina BALDOFSKI, Auteur ; Stephanie BAUER, Auteur ; Katja BECKER, Auteur ; Silke DIESTELKAMP, Auteur ; Alisa HIERY, Auteur ; Michael KAESS, Auteur ; Julian KOENIG, Auteur ; Sophia LUSTIG, Auteur ; Christine RUMMEL-KLUGE, Auteur ; Rainer THOMASIUS, Auteur ; Heike ESCHENBECK, Auteur ; Head Consortium THE PRO, Auteur . - p.1393-1403. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1393-1403 Mots-clés : Online  internet  prevention  intervention  adolescents  young people  mental health  mental illness Index. décimale : PER Périodiques Résumé : Background Given the high prevalence of mental illnesses in adolescents, there is an urgent need for effective prevention strategies. The aim of this study was to evaluate the school-based internet intervention StresSOS for the universal prevention of mental illnesses in youth. Methods A two-arm, randomized controlled trial was conducted. Participants were recruited from schools across five regions of Germany. Young people between the ages of 12 and 25?years without mental health problems were invited to the trial and randomly assigned to StresSOS or to the attention placebo control condition, stratified by sex. Participants in both conditions received eight web-based sessions with information and exercises and weekly e-mail teasers about program content and a monitoring survey. StresSOS comprised content on life skills, particularly stress management and mental health literacy, and the control condition content comprised healthy nutrition. The primary outcome was self-reported mental health status at a 12-month follow-up. Intention-to-treat analyses were calculated. The trial was preregistered with the German Register of Clinical Trials (DRKS00014693, see https://drks.de/search/en/trial/DRKS00014693). Results A total of 5,268 eligible students were invited to participate, 2,327 (44%) activated their account and were randomized to StresSOS (n?=?1,154) or to the control condition (n?=?1,173). Due to COVID-19-related school closures, 1,209 were lost to follow-up, and data from 1,118 students were analyzed (535 in StresSOS and 583 in the control group). Participation in StresSOS led to significantly reduced incidences of emerging mental health problems at the 12-month follow-up (controls: n?=?162 [28%] ?with problems?; StresSOS: n?=?113 [21%] ?with problems?; OR 0.70, 95% CI [0.52, 0.92], p?=?.01). Conclusions StresSOS was effective in universally preventing the onset of mental health problems, with a small effect. Internet interventions have the potential to contribute to a reduction of the disease burden in young people. En ligne : https://doi.org/10.1111/jcpp.70145 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=592

The association between inflammatory markers in routine blood counts at 1 year and attention-deficit/hyperactivity disorder (ADHD): A case–control study / Eugene MERZON in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1404-1411 Titre : The association between inflammatory markers in routine blood counts at 1 year and attention-deficit/hyperactivity disorder (ADHD): A case–control study Type de document : texte imprimé Auteurs : Eugene MERZON, Auteur ; Ariel ISRAEL, Auteur ; Shelly SALMINIS-LINZEN, Auteur ; Eli MAGEN, Auteur ; Akim GEISHIN, Auteur ; Shlomo VINKER, Auteur ; Ilan GREEN, Auteur ; Avivit GOLAN-COHEN, Auteur ; Shai ASHKENAZI, Auteur ; Stephen V. FARAONE, Auteur ; Abraham WEIZMAN, Auteur ; Iris MANOR, Auteur Article en page(s) : p.1404-1411 Langues : Anglais (eng) Mots-clés : ADHD  complete blood count  inflammation  biomarkers Index. décimale : PER Périodiques Résumé : Background Attention-deficit/hyperactivity disorder (ADHD) is a chronic neurodevelopmental disorder marked by persistent patterns of inattention, disorganization, hyperactivity, and impulsivity. Increasing evidence implicates immune-inflammatory processes in its etiology, with observed associations between ADHD and infectious diseases, allergic conditions, and recent findings involving SARS-CoV-2. This study investigated whether early-life inflammatory markers, as measured by routine complete blood counts (CBCs) in clinically healthy 1-year-old children, were associated with subsequent diagnoses of ADHD. Methods A retrospective case?control study was conducted using electronic medical records from Leumit Health Services, encompassing children under 18?years between January 1, 2006, and June 30, 2021. The sample included children who underwent routine CBC testing at age one during a well-child visit, without signs of acute illness. ADHD cases were identified based on ICD-9/10 criteria. Controls, free of any ADHD diagnosis, were randomly selected at a 1:2 ratio and matched for age, sex, socioeconomic status, and cultural sector. Analyses included white blood cell (WBC) subtypes and platelet counts, with the calculation of the neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR). Results Children who were subsequently diagnosed with ADHD demonstrated statistically significant elevated total WBC counts at age one, including higher neutrophil, eosinophil, and lymphocyte levels, and lower basophil counts compared to matched controls (all p < .05). No significant differences were observed in PLR between groups. Conclusions Elevated inflammatory markers were detectable in clinically healthy 1-year-old children who were later diagnosed with ADHD. These findings suggest a potential preclinical inflammatory phenotype linked to ADHD risk, highlighting the need for further investigation into early immune dysregulation as a contributing factor in ADHD pathophysiology. Early identification of such biomarkers may inform preventive strategies and targeted interventions in high-risk pediatric populations. En ligne : https://doi.org/10.1111/jcpp.70147 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=592 [article] The association between inflammatory markers in routine blood counts at 1 year and attention-deficit/hyperactivity disorder (ADHD): A case–control study [texte imprimé] / Eugene MERZON, Auteur ; Ariel ISRAEL, Auteur ; Shelly SALMINIS-LINZEN, Auteur ; Eli MAGEN, Auteur ; Akim GEISHIN, Auteur ; Shlomo VINKER, Auteur ; Ilan GREEN, Auteur ; Avivit GOLAN-COHEN, Auteur ; Shai ASHKENAZI, Auteur ; Stephen V. FARAONE, Auteur ; Abraham WEIZMAN, Auteur ; Iris MANOR, Auteur . - p.1404-1411. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1404-1411 Mots-clés : ADHD  complete blood count  inflammation  biomarkers Index. décimale : PER Périodiques Résumé : Background Attention-deficit/hyperactivity disorder (ADHD) is a chronic neurodevelopmental disorder marked by persistent patterns of inattention, disorganization, hyperactivity, and impulsivity. Increasing evidence implicates immune-inflammatory processes in its etiology, with observed associations between ADHD and infectious diseases, allergic conditions, and recent findings involving SARS-CoV-2. This study investigated whether early-life inflammatory markers, as measured by routine complete blood counts (CBCs) in clinically healthy 1-year-old children, were associated with subsequent diagnoses of ADHD. Methods A retrospective case?control study was conducted using electronic medical records from Leumit Health Services, encompassing children under 18?years between January 1, 2006, and June 30, 2021. The sample included children who underwent routine CBC testing at age one during a well-child visit, without signs of acute illness. ADHD cases were identified based on ICD-9/10 criteria. Controls, free of any ADHD diagnosis, were randomly selected at a 1:2 ratio and matched for age, sex, socioeconomic status, and cultural sector. Analyses included white blood cell (WBC) subtypes and platelet counts, with the calculation of the neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR). Results Children who were subsequently diagnosed with ADHD demonstrated statistically significant elevated total WBC counts at age one, including higher neutrophil, eosinophil, and lymphocyte levels, and lower basophil counts compared to matched controls (all p < .05). No significant differences were observed in PLR between groups. Conclusions Elevated inflammatory markers were detectable in clinically healthy 1-year-old children who were later diagnosed with ADHD. These findings suggest a potential preclinical inflammatory phenotype linked to ADHD risk, highlighting the need for further investigation into early immune dysregulation as a contributing factor in ADHD pathophysiology. Early identification of such biomarkers may inform preventive strategies and targeted interventions in high-risk pediatric populations. En ligne : https://doi.org/10.1111/jcpp.70147 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=592

Research Review: Measuring life impact of youth mental health difficulties: scoping umbrella review of 80 instruments / Karolin R. KRAUSE in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1412-1441 Titre : Research Review: Measuring life impact of youth mental health difficulties: scoping umbrella review of 80 instruments Type de document : texte imprimé Auteurs : Karolin R. KRAUSE, Auteur ; Sophie CHUNG, Auteur ; Christiane KONSTANTOPOULOS, Auteur ; Terri RODAK, Auteur ; Ana CALDERÓN, Auteur ; Nichol Edwards SNAGG, Auteur ; Kristin CLEVERLEY, Auteur ; Nancy J. BUTCHER, Auteur ; Giovanni A. SALUM, Auteur ; Kathleen R. MERIKANGAS, Auteur ; Peter SZATMARI, Auteur Article en page(s) : p.1412-1441 Langues : Anglais (eng) Mots-clés : Outcome measures  functioning  quality of life  well-being  children  adolescents Index. décimale : PER Périodiques Résumé : Background Mental health symptoms affect children and youths' functioning, quality of life (QOL), and well-being in daily life. While this ?life impact? is a critical outcome, there is a lack of conceptual clarity and widely endorsed outcome measurement instruments (OMI) to support consistent assessment across studies. This scoping umbrella review sought to map OMIs that assess life impact through measures of functioning, QOL, or well-being. Specifically, our aims were to: identify life impact OMIs from existing reviews, compare OMI design characteristics, descriptively appraise essential aspects of development quality for selected OMIs, and assess how consistently reviews identified OMI target constructs. Methods We searched six databases for systematic, scoping, rapid, or narrative reviews of functioning, QOL, or well-being OMIs for 6-to-24-year-olds with primary mental health concerns. We separately retrieved original development/validation reports for each OMI and extracted information on the target construct and key design characteristics. For a subset of OMIs, we descriptively appraised essential features of OMI development quality. Results We identified 80 OMIs of functioning (n?=?35), QOL (n?=?33), and well-being (n?=?12). Two-thirds were developed for children and youth up to 18?years, but none targeted young adults aged 19?24. Functioning OMIs were frequently designed for multi-informant assessment; QOL and well-being OMIs were mainly self-reported. Most functioning OMIs were originally validated in populations with mental health difficulties, unlike OMIs of QOL and well-being. For over one quarter of OMIs, the target construct was misclassified in at least one review, with frequent conflation of QOL and well-being. Conclusions Mental health difficulties impact life across functioning, QOL, and well-being. Life impact is a core outcome to track in clinical research and practice. This review provides a roadmap to selecting OMIs of life impact in youth mental health based on OMI design characteristics. En ligne : https://doi.org/10.1111/jcpp.70134 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=592 [article] Research Review: Measuring life impact of youth mental health difficulties: scoping umbrella review of 80 instruments [texte imprimé] / Karolin R. KRAUSE, Auteur ; Sophie CHUNG, Auteur ; Christiane KONSTANTOPOULOS, Auteur ; Terri RODAK, Auteur ; Ana CALDERÓN, Auteur ; Nichol Edwards SNAGG, Auteur ; Kristin CLEVERLEY, Auteur ; Nancy J. BUTCHER, Auteur ; Giovanni A. SALUM, Auteur ; Kathleen R. MERIKANGAS, Auteur ; Peter SZATMARI, Auteur . - p.1412-1441. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1412-1441 Mots-clés : Outcome measures  functioning  quality of life  well-being  children  adolescents Index. décimale : PER Périodiques Résumé : Background Mental health symptoms affect children and youths' functioning, quality of life (QOL), and well-being in daily life. While this ?life impact? is a critical outcome, there is a lack of conceptual clarity and widely endorsed outcome measurement instruments (OMI) to support consistent assessment across studies. This scoping umbrella review sought to map OMIs that assess life impact through measures of functioning, QOL, or well-being. Specifically, our aims were to: identify life impact OMIs from existing reviews, compare OMI design characteristics, descriptively appraise essential aspects of development quality for selected OMIs, and assess how consistently reviews identified OMI target constructs. Methods We searched six databases for systematic, scoping, rapid, or narrative reviews of functioning, QOL, or well-being OMIs for 6-to-24-year-olds with primary mental health concerns. We separately retrieved original development/validation reports for each OMI and extracted information on the target construct and key design characteristics. For a subset of OMIs, we descriptively appraised essential features of OMI development quality. Results We identified 80 OMIs of functioning (n?=?35), QOL (n?=?33), and well-being (n?=?12). Two-thirds were developed for children and youth up to 18?years, but none targeted young adults aged 19?24. Functioning OMIs were frequently designed for multi-informant assessment; QOL and well-being OMIs were mainly self-reported. Most functioning OMIs were originally validated in populations with mental health difficulties, unlike OMIs of QOL and well-being. For over one quarter of OMIs, the target construct was misclassified in at least one review, with frequent conflation of QOL and well-being. Conclusions Mental health difficulties impact life across functioning, QOL, and well-being. Life impact is a core outcome to track in clinical research and practice. This review provides a roadmap to selecting OMIs of life impact in youth mental health based on OMI design characteristics. En ligne : https://doi.org/10.1111/jcpp.70134 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=592

Research Review: Mathematical skills in children with developmental language disorder – a systematic review and meta-analysis / Anne Mari HØGETVEIT in Journal of Child Psychology and Psychiatry, 67-8 (August 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1442-1453 Titre : Research Review: Mathematical skills in children with developmental language disorder – a systematic review and meta-analysis Type de document : texte imprimé Auteurs : Anne Mari HØGETVEIT, Auteur ; Esther Tamara CANRINUS, Auteur ; Enrica DONOLATO, Auteur ; Monica MELBY-LERVÃ…G, Auteur Article en page(s) : p.1442-1453 Langues : Anglais (eng) Mots-clés : Developmental language disorders  mathematical skills  children  meta-analysis  systematic review Index. décimale : PER Périodiques Résumé : Background Language is an essential skill for learning and academic achievement; therefore, children with developmental language disorder (DLD) are at risk for learning difficulties. Previous research has indicated a higher prevalence of mathematical difficulties in children with DLD compared to control children without such difficulties. However, the extent to which DLD and mathematical difficulties co-occur, as well as the nature of the difficulties, remains unclear. Methods We performed a meta-analysis of 30 studies examining the mathematical skills of children with DLD compared to controls and examined moderators related to children's age, cognitive abilities, mathematical domains, diagnostic status, and publication type. Results Children with DLD performed approximately 1 SD (Hedges' g?=??1.03) below age-matched controls in mathematics. Group differences were moderated by the type of mathematical task, with children with DLD being more impaired in arithmetic, counting, word problems, and composite math skills than in tasks evaluating Arabic number knowledge and magnitude judgment. There was a small-study effect, but publication bias was not confirmed. Conclusions Children with DLD perform considerably more poorly than controls in mathematics and are at a high risk of mathematical difficulties. This supports the notion that these children have a complex profile of difficulties. En ligne : https://doi.org/10.1111/jcpp.70138 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=592 [article] Research Review: Mathematical skills in children with developmental language disorder – a systematic review and meta-analysis [texte imprimé] / Anne Mari HØGETVEIT, Auteur ; Esther Tamara CANRINUS, Auteur ; Enrica DONOLATO, Auteur ; Monica MELBY-LERVÃ…G, Auteur . - p.1442-1453. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-8 (August 2026) . - p.1442-1453 Mots-clés : Developmental language disorders  mathematical skills  children  meta-analysis  systematic review Index. décimale : PER Périodiques Résumé : Background Language is an essential skill for learning and academic achievement; therefore, children with developmental language disorder (DLD) are at risk for learning difficulties. Previous research has indicated a higher prevalence of mathematical difficulties in children with DLD compared to control children without such difficulties. However, the extent to which DLD and mathematical difficulties co-occur, as well as the nature of the difficulties, remains unclear. Methods We performed a meta-analysis of 30 studies examining the mathematical skills of children with DLD compared to controls and examined moderators related to children's age, cognitive abilities, mathematical domains, diagnostic status, and publication type. Results Children with DLD performed approximately 1 SD (Hedges' g?=??1.03) below age-matched controls in mathematics. Group differences were moderated by the type of mathematical task, with children with DLD being more impaired in arithmetic, counting, word problems, and composite math skills than in tasks evaluating Arabic number knowledge and magnitude judgment. There was a small-study effect, but publication bias was not confirmed. Conclusions Children with DLD perform considerably more poorly than controls in mathematics and are at a high risk of mathematical difficulties. This supports the notion that these children have a complex profile of difficulties. En ligne : https://doi.org/10.1111/jcpp.70138 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=592