- <Centre d'Information et de documentation du CRA Rhône-Alpes
- CRA
- Informations pratiques
-
Adresse
Centre d'information et de documentation
Horaires
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexLundi au Vendredi
Contact
9h00-12h00 13h30-16h00Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Adresse
Détail de l'indexation
PER : Périodiques |
Ouvrages de la bibliothèque en indexation PER (29993)
Faire une suggestion Affiner la recherche1-5 - October 2008 (Bulletin de Autism Research)
Titre : 1-5 - October 2008 Type de document : Texte imprimé et/ou numérique Année de publication : 2008 Index. décimale : PER Périodiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=bulletin_display&id=4 [n° ou bulletin] 1-5 - October 2008 [Texte imprimé et/ou numérique] . - 2008.
Index. décimale : PER Périodiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=bulletin_display&id=4 Contient
- Postmortem studies of autism / Anthony J. BAILEY in Autism Research, 1-5 (October 2008)
- Relationships between multiple births and autism spectrum disorders, cerebral palsy, and intellectual disabilities: autism and developmental disabilities monitoring (ADDM) network - 2002 surveillance year / Kim VAN NAARDEN BRAUN in Autism Research, 1-5 (October 2008)
- Reduced levels of immunoglobulin in children with autism correlates with behavioral symptoms / Luke HEUER in Autism Research, 1-5 (October 2008)
- Overlap between autism and specific language impairment: comparison of Autism Diagnostic Interview and Autism Diagnostic Observation Schedule scores / Ovsanna T. LEYFER in Autism Research, 1-5 (October 2008)
- Face inversion effects in autism: a combined looking time and pupillometric study / Terje FALCK-YTTER in Autism Research, 1-5 (October 2008)
- Addendum : Feasibility and relevance of examining lymphoblastoid cell lines to study role of microRNAs in autism / Zohreh TALEBIZADEH in Autism Research, 1-5 (October 2008)
- Literature review: adult structural MRI, postmortem GABA-A protein, 1q21.1 microdeletion/microduplication / Edwin H. Jr COOK in Autism Research, 1-5 (October 2008)
- Lay abstracts in Autism Research, 1-5 (October 2008)
- The International Meeting for Autism Research in Autism Research, 1-5 (October 2008)
- International Society for Autism Research News in Autism Research, 1-5 (October 2008)
Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité PER0000405 PER ARI Périodique Centre d'Information et de Documentation du CRA Rhône-Alpes PER - Périodiques Exclu du prêt
Titre : 1-6 - December 2008 Type de document : Texte imprimé et/ou numérique Année de publication : 2008 Index. décimale : PER Périodiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=bulletin_display&id=4 [n° ou bulletin] 1-6 - December 2008 [Texte imprimé et/ou numérique] . - 2008.
Index. décimale : PER Périodiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=bulletin_display&id=4 Contient
- Neuroimaging Research in Autism: The Next Decade / Robert T. SCHULTZ in Autism Research, 1-6 (December 2008)
- The onset of autism: patterns of symptom emergence in the first years of life / Sally OZONOFF in Autism Research, 1-6 (December 2008)
- Specific impairment of face-processing abilities in children with autism spectrum disorder using the Let's Face It! skills battery / Julie M. WOLF in Autism Research, 1-6 (December 2008)
- Evidence that the pattern of visuomotor sequence learning is altered in children with autism / Jennifer C. GIDLEY-LARSON in Autism Research, 1-6 (December 2008)
- Assessing autistic traits: cross-cultural validation of the social responsiveness scale (SRS) / Sven BÖLTE in Autism Research, 1-6 (December 2008)
- Examination of association to autism of common genetic variationin genes related to dopamine / B.M. ANDERSON in Autism Research, 1-6 (December 2008)
- Literature Review: Overlapping genetic association in developmental language disorder and autism; Grey matter in high functioning autism and Asperger's syndrome; Brain activation in self-other face discrimination / Edwin H. Jr COOK in Autism Research, 1-6 (December 2008)
- Lay abstracts in Autism Research, 1-6 (December 2008)
- The International Meeting for Autism Research in Autism Research, 1-6 (December 2008)
- International Society for Autism Research News in Autism Research, 1-6 (December 2008)
Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité PER0000406 PER ARI Périodique Centre d'Information et de Documentation du CRA Rhône-Alpes PER - Périodiques Exclu du prêt 1 groupe, 2 jours, 3 enfants : en avant la musique! / Sophie BEGUET in Rééducation Orthophonique, 249 (Mars 2012)
Titre : 1 groupe, 2 jours, 3 enfants : en avant la musique! Type de document : Texte imprimé et/ou numérique Auteurs : Sophie BEGUET, Auteur ; Karine MAHE-BUISSON, Auteur Année de publication : 2012 Article en page(s) : p.129-138 Langues : Français (fre) Mots-clés : TED enfant musique groupe communication. Index. décimale : PER Périodiques Résumé : Les enfants porteurs de TED ont des altérations marquées de la communication verbale et non verbale et, de plus, ils montrent parfois une appétence particulière pour le monde sonore. Après avoir réfléchi sur l’intérêt de cette médiation et l’élaboration en CMP d’un groupe thérapeutique utilisant la musique, deux soignantes (orthophoniste et infirmière) ont mis en place un groupe pour trois enfants de petite section de maternelle et présentant un important retard de développement global. Le groupe médiation sonore a eu une mise en place laborieuse et les difficultés de ces enfants sont tellement lourdes que le temps d’accordage est long. Au fil du temps, les enfants se saisissant de cette médiation et de ce temps relationnel ont évolué dans le sens de l’ouverture vers autrui et du plaisir à jouer. Globalement, le bilan paraît positif et chaque enfant montre des signes évidents de progression Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=164
in Rééducation Orthophonique > 249 (Mars 2012) . - p.129-138[article] 1 groupe, 2 jours, 3 enfants : en avant la musique! [Texte imprimé et/ou numérique] / Sophie BEGUET, Auteur ; Karine MAHE-BUISSON, Auteur . - 2012 . - p.129-138.
Langues : Français (fre)
in Rééducation Orthophonique > 249 (Mars 2012) . - p.129-138
Mots-clés : TED enfant musique groupe communication. Index. décimale : PER Périodiques Résumé : Les enfants porteurs de TED ont des altérations marquées de la communication verbale et non verbale et, de plus, ils montrent parfois une appétence particulière pour le monde sonore. Après avoir réfléchi sur l’intérêt de cette médiation et l’élaboration en CMP d’un groupe thérapeutique utilisant la musique, deux soignantes (orthophoniste et infirmière) ont mis en place un groupe pour trois enfants de petite section de maternelle et présentant un important retard de développement global. Le groupe médiation sonore a eu une mise en place laborieuse et les difficultés de ces enfants sont tellement lourdes que le temps d’accordage est long. Au fil du temps, les enfants se saisissant de cette médiation et de ce temps relationnel ont évolué dans le sens de l’ouverture vers autrui et du plaisir à jouer. Globalement, le bilan paraît positif et chaque enfant montre des signes évidents de progression Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=164
Titre : (1)H-NMR-based metabolomics reveals metabolic alterations in early development of a mouse model of Angelman syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Pooja Kri GUPTA, Auteur ; Sharon BARAK, Auteur ; Yonatan FEUERMANN, Auteur ; Gil GOOBES, Auteur ; Hanoch KAPHZAN, Auteur Article en page(s) : 31p. Langues : Anglais (eng) Mots-clés : Animals Angelman Syndrome/metabolism/genetics Metabolomics Disease Models, Animal Brain/metabolism/diagnostic imaging Mice Proton Magnetic Resonance Spectroscopy Metabolome Ubiquitin-Protein Ligases/metabolism/genetics Female Acetate Angelman syndrome Developmental disorders Glycolysis Lactate Metabolite Mitochondria Pyruvate metabolism Reactive oxygen species Succinate Index. décimale : PER Périodiques Résumé : BACKGROUND: Angelman syndrome (AS) is a rare neurodevelopmental genetic disorder caused by the loss of function of the ubiquitin ligase E3A (UBE3A) gene, affecting approximately 1:15,000 live births. We have recently shown that mitochondrial function in AS is altered during mid to late embryonic brain development leading to increased oxidative stress and enhanced apoptosis of neural precursor cells. However, the overall alterations of metabolic processes are still unknown. Hence, as a follow-up, we aim to investigate the metabolic profiles of wild-type (WT) and AS littermates and to identify which metabolic processes are aberrant in the brain of AS model mice during embryonic development. METHODS: We collected brain tissue samples from mice embryos at E16.5 and performed metabolomic analyses using proton nuclear magnetic resonance ((1)H-NMR) spectroscopy. Multivariate and Univariate analyses were performed to determine the significantly altered metabolites in AS mice. Pathways associated with the altered metabolites were identified using metabolite set enrichment analysis. RESULTS: Our analysis showed that overall, the metabolomic fingerprint of AS embryonic brains differed from those of their WT littermates. Moreover, we revealed a significant elevation of distinct metabolites, such as acetate, lactate, and succinate in the AS samples compared to the WT samples. The elevated metabolites were significantly associated with the pyruvate metabolism and glycolytic pathways. LIMITATIONS: Only 14 metabolites were successfully identified and investigated in the present study. The effect of unidentified metabolites and their unresolved peaks was not determined. Additionally, we conducted the metabolomic study on whole brain tissue samples. Employing high-resolution NMR studies on different brain regions could further expand our knowledge regarding metabolic alterations in the AS brain. Furthermore, increasing the sample size could reveal the involvement of more significantly altered metabolites in the pathophysiology of the AS brain. CONCLUSIONS: Ube3a loss of function alters bioenergy-related metabolism in the AS brain during embryonic development. Furthermore, these neurochemical changes could be linked to the mitochondrial reactive oxygen species and oxidative stress that occurs during the AS embryonic development. En ligne : https://dx.doi.org/10.1186/s13229-024-00608-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=538
in Molecular Autism > 15 (2024) . - 31p.[article] (1)H-NMR-based metabolomics reveals metabolic alterations in early development of a mouse model of Angelman syndrome [Texte imprimé et/ou numérique] / Pooja Kri GUPTA, Auteur ; Sharon BARAK, Auteur ; Yonatan FEUERMANN, Auteur ; Gil GOOBES, Auteur ; Hanoch KAPHZAN, Auteur . - 31p.
Langues : Anglais (eng)
in Molecular Autism > 15 (2024) . - 31p.
Mots-clés : Animals Angelman Syndrome/metabolism/genetics Metabolomics Disease Models, Animal Brain/metabolism/diagnostic imaging Mice Proton Magnetic Resonance Spectroscopy Metabolome Ubiquitin-Protein Ligases/metabolism/genetics Female Acetate Angelman syndrome Developmental disorders Glycolysis Lactate Metabolite Mitochondria Pyruvate metabolism Reactive oxygen species Succinate Index. décimale : PER Périodiques Résumé : BACKGROUND: Angelman syndrome (AS) is a rare neurodevelopmental genetic disorder caused by the loss of function of the ubiquitin ligase E3A (UBE3A) gene, affecting approximately 1:15,000 live births. We have recently shown that mitochondrial function in AS is altered during mid to late embryonic brain development leading to increased oxidative stress and enhanced apoptosis of neural precursor cells. However, the overall alterations of metabolic processes are still unknown. Hence, as a follow-up, we aim to investigate the metabolic profiles of wild-type (WT) and AS littermates and to identify which metabolic processes are aberrant in the brain of AS model mice during embryonic development. METHODS: We collected brain tissue samples from mice embryos at E16.5 and performed metabolomic analyses using proton nuclear magnetic resonance ((1)H-NMR) spectroscopy. Multivariate and Univariate analyses were performed to determine the significantly altered metabolites in AS mice. Pathways associated with the altered metabolites were identified using metabolite set enrichment analysis. RESULTS: Our analysis showed that overall, the metabolomic fingerprint of AS embryonic brains differed from those of their WT littermates. Moreover, we revealed a significant elevation of distinct metabolites, such as acetate, lactate, and succinate in the AS samples compared to the WT samples. The elevated metabolites were significantly associated with the pyruvate metabolism and glycolytic pathways. LIMITATIONS: Only 14 metabolites were successfully identified and investigated in the present study. The effect of unidentified metabolites and their unresolved peaks was not determined. Additionally, we conducted the metabolomic study on whole brain tissue samples. Employing high-resolution NMR studies on different brain regions could further expand our knowledge regarding metabolic alterations in the AS brain. Furthermore, increasing the sample size could reveal the involvement of more significantly altered metabolites in the pathophysiology of the AS brain. CONCLUSIONS: Ube3a loss of function alters bioenergy-related metabolism in the AS brain during embryonic development. Furthermore, these neurochemical changes could be linked to the mitochondrial reactive oxygen species and oxidative stress that occurs during the AS embryonic development. En ligne : https://dx.doi.org/10.1186/s13229-024-00608-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=538
Titre : 1 - January-December 2016 Type de document : Texte imprimé et/ou numérique Année de publication : 2016 Langues : Anglais (eng) Index. décimale : PER Périodiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=bulletin_display&id=2 [n° ou bulletin] 1 - January-December 2016 [Texte imprimé et/ou numérique] . - 2016.
Langues : Anglais (eng)
Index. décimale : PER Périodiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=bulletin_display&id=2 Contient
- Language impairments in childhood – A range of profiles, a variety of reasons / Nicola BOTTING in Autism & Developmental Language Impairments, 1 (January-December 2016)
- Body movement imitation and early language as predictors of later social communication and language outcomes: A longitudinal study / Andrea DOHMEN in Autism & Developmental Language Impairments, 1 (January-December 2016)
- Declarative capacity does not trade-off with procedural capacity in children with specific language impairment / Sengottuvel KUPPURAJ in Autism & Developmental Language Impairments, 1 (January-December 2016)
- Conduct problems co-occur with hyperactivity in children with language impairment: A longitudinal study from childhood to adolescence / Andrew PICKLES in Autism & Developmental Language Impairments, 1 (January-December 2016)
Exemplaires
Code-barres Cote Support Localisation Section Disponibilité aucun exemplaire
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
Permalink
