Dépouillements

Probiotic intervention in young children with autism spectrum disorder in Taiwan: A randomized, double-blinded, placebo-controlled trial / Jia-En WANG ; Fang-Ju SUN ; Yu-Hsin HUANG ; Hui-Ju CHEN in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102256 Titre : Probiotic intervention in young children with autism spectrum disorder in Taiwan: A randomized, double-blinded, placebo-controlled trial Type de document : Texte imprimé et/ou numérique Auteurs : Jia-En WANG, Auteur ; Fang-Ju SUN, Auteur ; Yu-Hsin HUANG, Auteur ; Hui-Ju CHEN, Auteur Article en page(s) : 102256 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder (ASD)  Preschool  Probiotic  Psychobiotic  Anxious/depressed Index. décimale : PER Périodiques Résumé : Background The impact of psychobiotics on ASD is unclear. Method In this double-blinded, randomized, placebo-controlled trial, 86 children (aged 2.5-7 years) with ASD were recruited and assigned randomly to either the probiotic or placebo group to explore the effects of the probiotic Lactobacillus plantarum PS128 (PS128). During the first 2 months of the study, the children received either the probiotic or placebo. After that, all of the children received PS128 for 2 more months. We categorized individuals who took PS128 for the entire 4-month duration as the "PS128 early use group" (E group), while those who initially received the placebo for 2 months and then took PS128 for the subsequent 2 months were classified as the "PS128 late use group" (L group). Results After adjusting for possible confounders, the results showed that the anxious/depressed subscale score of the Achenbach System of Empirically Based Assessment significantly improved in the E group after the first 2-month intervention (P = 0.044) when compared to the L group. In the subsequent 2 months, the L group showed a significant improvement in this subscale (P = 0.017). While the improvement observed during the first two months was not sustained on average in the E group from V2 to V3, this variability can be attributed to the influence of an outlier. Upon analyzing the hyperactivity subscale of the Attention-Deficit/Hyperactivity Disorder Test, no significant differences were found across multiple time points. Conclusions The results support that PS128 has beneficial effects on behavioral and emotional problems in young children with ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102256 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517 [article] Probiotic intervention in young children with autism spectrum disorder in Taiwan: A randomized, double-blinded, placebo-controlled trial [Texte imprimé et/ou numérique] / Jia-En WANG, Auteur ; Fang-Ju SUN, Auteur ; Yu-Hsin HUANG, Auteur ; Hui-Ju CHEN, Auteur . - 102256. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102256 Mots-clés : Autism spectrum disorder (ASD)  Preschool  Probiotic  Psychobiotic  Anxious/depressed Index. décimale : PER Périodiques Résumé : Background The impact of psychobiotics on ASD is unclear. Method In this double-blinded, randomized, placebo-controlled trial, 86 children (aged 2.5-7 years) with ASD were recruited and assigned randomly to either the probiotic or placebo group to explore the effects of the probiotic Lactobacillus plantarum PS128 (PS128). During the first 2 months of the study, the children received either the probiotic or placebo. After that, all of the children received PS128 for 2 more months. We categorized individuals who took PS128 for the entire 4-month duration as the "PS128 early use group" (E group), while those who initially received the placebo for 2 months and then took PS128 for the subsequent 2 months were classified as the "PS128 late use group" (L group). Results After adjusting for possible confounders, the results showed that the anxious/depressed subscale score of the Achenbach System of Empirically Based Assessment significantly improved in the E group after the first 2-month intervention (P = 0.044) when compared to the L group. In the subsequent 2 months, the L group showed a significant improvement in this subscale (P = 0.017). While the improvement observed during the first two months was not sustained on average in the E group from V2 to V3, this variability can be attributed to the influence of an outlier. Upon analyzing the hyperactivity subscale of the Attention-Deficit/Hyperactivity Disorder Test, no significant differences were found across multiple time points. Conclusions The results support that PS128 has beneficial effects on behavioral and emotional problems in young children with ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102256 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517

Autism spectrum disorder detection using variable frequency complex demodulation of the electroretinogram / Sultan Mohammad MANJUR ; Md Billal HOSSAIN ; Fernando MARMOLEJO-RAMOS ; Irene O. LEE ; David H. SKUSE ; Dorothy A. THOMPSON ; Paul A. CONSTABLE in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102258 Titre : Autism spectrum disorder detection using variable frequency complex demodulation of the electroretinogram Type de document : Texte imprimé et/ou numérique Auteurs : Sultan Mohammad MANJUR, Auteur ; Md Billal HOSSAIN, Auteur ; Fernando MARMOLEJO-RAMOS, Auteur ; Irene O. LEE, Auteur ; David H. SKUSE, Auteur ; Dorothy A. THOMPSON, Auteur ; Paul A. CONSTABLE, Auteur Article en page(s) : 102258 Langues : Anglais (eng) Mots-clés : Electroretinogram  Signal analysis  Autism spectrum disorder  Machine learning Index. décimale : PER Périodiques Résumé : The early diagnosis of neurodevelopmental conditions such as autism spectrum disorder (ASD), is an unmet need. One difficulty is the identification of a biological signal that relates to the ASD phenotype. The electroretinogram (ERG) waveform has been identified as a possible signal that could categorize neurological conditions such as ASD. The ERG waveform is derived from the electrical activity of photoreceptors and retinal neurons in response to a brief flash of light and provides an indirect 'window' into the central nervous system. Traditionally, the waveform is analyzed in the time-domain, but more recently time-frequency spectrum (TFS) analysis of ERG has been successfully carried out using discrete wavelet transformation (DWT) to characterize the morphological features of the signal. In this study, we propose the use of a high resolution TFS technique, namely variable frequency complex demodulation (VFCDM), to decompose the ERG waveform based on two signal flash strengths to build machine learning (ML) models to categorize ASD. ERG waveforms from N = 217 subjects (71 ASD, 146 control), at two different flash strengths, 446 and 113 Troland seconds (Td.s), from both right and left eyes were included. We analyzed the raw ERG waveforms using DWT and VFCDM. We computed features from the TFSs and trained ML models such as Random Forest, Gradient Boosting, Support Vector Machine to classify ASD from controls. ML models were validated using a subject independent validation strategy, and we found that the ML models with VFCDM features outperformed models using the DWT, achieving an area under the receiver operating characteristics curve of 0.90 (accuracy = 0.81, sensitivity = 0.85, specificity = 0.78). We found that the higher frequency range (80-300 Hz) included more relevant information for classifying ASD compared to the lower frequencies. We also found that the stronger flash strength of 446 Td.s in the right eye provided the best classification result which supports VFCDM analysis of the ERG waveform as a potential tool to aid in the identification of the ASD phenotype. En ligne : https://doi.org/10.1016/j.rasd.2023.102258 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517 [article] Autism spectrum disorder detection using variable frequency complex demodulation of the electroretinogram [Texte imprimé et/ou numérique] / Sultan Mohammad MANJUR, Auteur ; Md Billal HOSSAIN, Auteur ; Fernando MARMOLEJO-RAMOS, Auteur ; Irene O. LEE, Auteur ; David H. SKUSE, Auteur ; Dorothy A. THOMPSON, Auteur ; Paul A. CONSTABLE, Auteur . - 102258. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102258 Mots-clés : Electroretinogram  Signal analysis  Autism spectrum disorder  Machine learning Index. décimale : PER Périodiques Résumé : The early diagnosis of neurodevelopmental conditions such as autism spectrum disorder (ASD), is an unmet need. One difficulty is the identification of a biological signal that relates to the ASD phenotype. The electroretinogram (ERG) waveform has been identified as a possible signal that could categorize neurological conditions such as ASD. The ERG waveform is derived from the electrical activity of photoreceptors and retinal neurons in response to a brief flash of light and provides an indirect 'window' into the central nervous system. Traditionally, the waveform is analyzed in the time-domain, but more recently time-frequency spectrum (TFS) analysis of ERG has been successfully carried out using discrete wavelet transformation (DWT) to characterize the morphological features of the signal. In this study, we propose the use of a high resolution TFS technique, namely variable frequency complex demodulation (VFCDM), to decompose the ERG waveform based on two signal flash strengths to build machine learning (ML) models to categorize ASD. ERG waveforms from N = 217 subjects (71 ASD, 146 control), at two different flash strengths, 446 and 113 Troland seconds (Td.s), from both right and left eyes were included. We analyzed the raw ERG waveforms using DWT and VFCDM. We computed features from the TFSs and trained ML models such as Random Forest, Gradient Boosting, Support Vector Machine to classify ASD from controls. ML models were validated using a subject independent validation strategy, and we found that the ML models with VFCDM features outperformed models using the DWT, achieving an area under the receiver operating characteristics curve of 0.90 (accuracy = 0.81, sensitivity = 0.85, specificity = 0.78). We found that the higher frequency range (80-300 Hz) included more relevant information for classifying ASD compared to the lower frequencies. We also found that the stronger flash strength of 446 Td.s in the right eye provided the best classification result which supports VFCDM analysis of the ERG waveform as a potential tool to aid in the identification of the ASD phenotype. En ligne : https://doi.org/10.1016/j.rasd.2023.102258 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517

Peripheral markers of nitrosative stress in children with autism spectrum disorder and bipolar disorder comorbidity during euthymic phase / Ali KARAYAGMURLU ; Canan KUCUKGERGIN ; Ilknur BINGUL ; Murat COSKUN in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102259 Titre : Peripheral markers of nitrosative stress in children with autism spectrum disorder and bipolar disorder comorbidity during euthymic phase Type de document : Texte imprimé et/ou numérique Auteurs : Ali KARAYAGMURLU, Auteur ; Canan KUCUKGERGIN, Auteur ; Ilknur BINGUL, Auteur ; Murat COSKUN, Auteur Article en page(s) : 102259 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Bipolar disorder  Biomarker  Nitrosative stress  Nitric oxide  3-nitrotyrosine  Nitric oxide synthetase Index. décimale : PER Périodiques Résumé : Background Bipolar Disorder (BD) is often comorbid with Autism Spectrum Disorder (ASD) (Skokauskas & Frodl, 2015). However, to our knowledge, the etiological pathways of BD comorbidity in individuals with ASD was not given a particular focus in the literature. The present study aims to investigate the link between BD comorbidity and nitrosative stress in children and adolescents with ASD. Method The case group consisted of 41 participants with comorbid ASD and BD, while the control group consisted of 39 participants with ASD who did not have any past or present mood disorders. As indicators of nitrosative stress, serum levels of NO (Nitric Oxide), NO2/NO3 (Nitrite/Nitrate), 3-NT (3-Nitrotyrosine) and NOS-I (Nitric Oxide Synthetase-I) were compared between groups. Results Serum levels of NO and 3-NT were significantly higher in the case group. As the phenomenological findings of BD, the age of onset was 10.5, mixed attack rate was 70%, seasonality rate was 63.8%, and sub-threshold symptoms were seen in 36.6% of the cases. Conclusion The present study indicated a relationship between BD comorbidity and nitrosative stress cascade among children and adolescents with ASD. Further studies with larger samples are needed to better understand the etiology of BD comorbidity in patients with ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102259 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517 [article] Peripheral markers of nitrosative stress in children with autism spectrum disorder and bipolar disorder comorbidity during euthymic phase [Texte imprimé et/ou numérique] / Ali KARAYAGMURLU, Auteur ; Canan KUCUKGERGIN, Auteur ; Ilknur BINGUL, Auteur ; Murat COSKUN, Auteur . - 102259. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102259 Mots-clés : Autism spectrum disorder  Bipolar disorder  Biomarker  Nitrosative stress  Nitric oxide  3-nitrotyrosine  Nitric oxide synthetase Index. décimale : PER Périodiques Résumé : Background Bipolar Disorder (BD) is often comorbid with Autism Spectrum Disorder (ASD) (Skokauskas & Frodl, 2015). However, to our knowledge, the etiological pathways of BD comorbidity in individuals with ASD was not given a particular focus in the literature. The present study aims to investigate the link between BD comorbidity and nitrosative stress in children and adolescents with ASD. Method The case group consisted of 41 participants with comorbid ASD and BD, while the control group consisted of 39 participants with ASD who did not have any past or present mood disorders. As indicators of nitrosative stress, serum levels of NO (Nitric Oxide), NO2/NO3 (Nitrite/Nitrate), 3-NT (3-Nitrotyrosine) and NOS-I (Nitric Oxide Synthetase-I) were compared between groups. Results Serum levels of NO and 3-NT were significantly higher in the case group. As the phenomenological findings of BD, the age of onset was 10.5, mixed attack rate was 70%, seasonality rate was 63.8%, and sub-threshold symptoms were seen in 36.6% of the cases. Conclusion The present study indicated a relationship between BD comorbidity and nitrosative stress cascade among children and adolescents with ASD. Further studies with larger samples are needed to better understand the etiology of BD comorbidity in patients with ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102259 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517

Barriers and facilitators to supporting Canadian autistic postsecondary students: Experiences of accessible learning staff and administrators / Jonathan VINCENT ; Carly A. MCMORRIS ; Megan E. AMES in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102260 Titre : Barriers and facilitators to supporting Canadian autistic postsecondary students: Experiences of accessible learning staff and administrators Type de document : Texte imprimé et/ou numérique Auteurs : Jonathan VINCENT, Auteur ; Carly A. MCMORRIS, Auteur ; Megan E. AMES, Auteur Article en page(s) : 102260 Langues : Anglais (eng) Mots-clés : Autism  Higher education  Postsecondary education  Supports  Academic staff Index. décimale : PER Périodiques Résumé : Background Specific supports like social skills training, support groups, and mentorship programs can improve autistic postsecondary students' chances of success. To improve inclusion practices, it is vital to understand the experiences of key staff and administrators who support autistic students during their postsecondary education. This mixed-methods study provides insight into the scope, strengths, and weaknesses of autism-specific services among Canadian universities from the perspective of university staff and administrators associated with accessibility services. Method Thirty-six staff and administrators (N = 36) from publicly-funded Canadian universities responded to an online survey, and eight participated in a follow-up semi-structured interview. Descriptive statistics and reflexive thematic analysis were conducted. Results Half of the participants endorsed having support for autistic students; the most common being for transition to university. Main obstacles to providing autism-specific supports included a need for more funding, knowledgeable staff, and institutional support. In the interviews, participants reported a strong desire to support autistic students; however, noted several barriers, including under-resourced challenges faced by staff and limitations to funding. Conclusions Findings highlight financial and practical challenges to supporting autistic students on postsecondary campuses. We advocate for the implementation and evaluation of wrap-around services for autistic students to enhance their success and promote social inclusion. Achieving this will require changes at all levels of the university system, including leadership and policy decisions involving autistic advocates' perspectives. En ligne : https://doi.org/10.1016/j.rasd.2023.102260 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517 [article] Barriers and facilitators to supporting Canadian autistic postsecondary students: Experiences of accessible learning staff and administrators [Texte imprimé et/ou numérique] / Jonathan VINCENT, Auteur ; Carly A. MCMORRIS, Auteur ; Megan E. AMES, Auteur . - 102260. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102260 Mots-clés : Autism  Higher education  Postsecondary education  Supports  Academic staff Index. décimale : PER Périodiques Résumé : Background Specific supports like social skills training, support groups, and mentorship programs can improve autistic postsecondary students' chances of success. To improve inclusion practices, it is vital to understand the experiences of key staff and administrators who support autistic students during their postsecondary education. This mixed-methods study provides insight into the scope, strengths, and weaknesses of autism-specific services among Canadian universities from the perspective of university staff and administrators associated with accessibility services. Method Thirty-six staff and administrators (N = 36) from publicly-funded Canadian universities responded to an online survey, and eight participated in a follow-up semi-structured interview. Descriptive statistics and reflexive thematic analysis were conducted. Results Half of the participants endorsed having support for autistic students; the most common being for transition to university. Main obstacles to providing autism-specific supports included a need for more funding, knowledgeable staff, and institutional support. In the interviews, participants reported a strong desire to support autistic students; however, noted several barriers, including under-resourced challenges faced by staff and limitations to funding. Conclusions Findings highlight financial and practical challenges to supporting autistic students on postsecondary campuses. We advocate for the implementation and evaluation of wrap-around services for autistic students to enhance their success and promote social inclusion. Achieving this will require changes at all levels of the university system, including leadership and policy decisions involving autistic advocates' perspectives. En ligne : https://doi.org/10.1016/j.rasd.2023.102260 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517

A comprehensive bioinformatics analysis of circRNA expression in the brain of distinct mouse models of Autism Spectrum Disorder / Guilherme Cordenonsi DA FONSECA ; Carmem GOTTFRIED in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102261 Titre : A comprehensive bioinformatics analysis of circRNA expression in the brain of distinct mouse models of Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Guilherme Cordenonsi DA FONSECA, Auteur ; Carmem GOTTFRIED, Auteur Article en page(s) : 102261 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Animal models  Circular RNA  Bioinformatics  NcRNAs Index. décimale : PER Périodiques Résumé : Background Autism Spectrum Disorder (ASD) is a neurodevelopmental condition estimated to affect 1% of individuals worldwide. Its etiology is still not fully understood, but several molecular alterations in ASD are related to noncoding RNAs (ncRNAs). Recently, gene expression of circular RNAs (circRNAs) has been shown to be altered in the brains of autistic individuals and two animal models of ASD. Here we use bioinformatics methods to analyze the gene expression of circRNAs in the brain of six distinct animal models of ASD and identify possible alterations shared between models and between models and humans. Method: six publicly available RNA-Seq data sets were used. CircRNAs were identified by a combination of algorithms using CirComPara2 software. Differentially expressed circRNAs (DECs) were evaluatedwith the Limma Voom method, and the functional profile was evaluated with clusterProfiler. Databases of risk genes and circRNAs altered in ASD were used for translational comparison. Results: We have identified over 130,000 unique circRNAs. DECs per se are shared by a few animal models. However, functional analysis revealed that the DECs from distinct models share a similar profile of changes, mostly related to synaptic structure and function. Regarding translational alterations, around 2% of DECs in mice are orthologous to DECs in autistic individuals. Conclusions: We provide an overview of the expression of circRNAs in mouse models of ASD. The analyses indicate that synaptic circRNAs may be central to the alterations found. We hope the broad identification of circRNAs can help researchers further explore their selected mouse models. En ligne : https://doi.org/10.1016/j.rasd.2023.102261 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517 [article] A comprehensive bioinformatics analysis of circRNA expression in the brain of distinct mouse models of Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Guilherme Cordenonsi DA FONSECA, Auteur ; Carmem GOTTFRIED, Auteur . - 102261. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102261 Mots-clés : Autism spectrum disorder  Animal models  Circular RNA  Bioinformatics  NcRNAs Index. décimale : PER Périodiques Résumé : Background Autism Spectrum Disorder (ASD) is a neurodevelopmental condition estimated to affect 1% of individuals worldwide. Its etiology is still not fully understood, but several molecular alterations in ASD are related to noncoding RNAs (ncRNAs). Recently, gene expression of circular RNAs (circRNAs) has been shown to be altered in the brains of autistic individuals and two animal models of ASD. Here we use bioinformatics methods to analyze the gene expression of circRNAs in the brain of six distinct animal models of ASD and identify possible alterations shared between models and between models and humans. Method: six publicly available RNA-Seq data sets were used. CircRNAs were identified by a combination of algorithms using CirComPara2 software. Differentially expressed circRNAs (DECs) were evaluatedwith the Limma Voom method, and the functional profile was evaluated with clusterProfiler. Databases of risk genes and circRNAs altered in ASD were used for translational comparison. Results: We have identified over 130,000 unique circRNAs. DECs per se are shared by a few animal models. However, functional analysis revealed that the DECs from distinct models share a similar profile of changes, mostly related to synaptic structure and function. Regarding translational alterations, around 2% of DECs in mice are orthologous to DECs in autistic individuals. Conclusions: We provide an overview of the expression of circRNAs in mouse models of ASD. The analyses indicate that synaptic circRNAs may be central to the alterations found. We hope the broad identification of circRNAs can help researchers further explore their selected mouse models. En ligne : https://doi.org/10.1016/j.rasd.2023.102261 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517

Environmental interventions supporting autistic transition-age youth employability: A scoping review / Mehmet KARAKUS ; Filiz POLAT in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102262 Titre : Environmental interventions supporting autistic transition-age youth employability: A scoping review Type de document : Texte imprimé et/ou numérique Auteurs : Mehmet KARAKUS, Auteur ; Filiz POLAT, Auteur Article en page(s) : 102262 Langues : Anglais (eng) Mots-clés : Autism  Environment  Transition-age youth  Employment  Vocational outcomes Index. décimale : PER Périodiques Résumé : Background Navigating the transition from school to work presents a challenge to many young people, and for autistic youth the challenge can be such that they never make it into employment. A greater understanding of interventions that support this important transition is needed. Method We conducted a scoping review of existing literature focusing on environmental interventions to support transition age youth preparing for employment. We categorized and analyzed the corpus of articles against the "environmental factors' aspect of the International Classification of Functioning, Disability and Health (ICF) published by the World Health Organization. Results The five domains of environmental factors including the physical, social, and attitudinal environment in which people live offer an a priori framework to identify interventions that have been used globally to address autistic individuals' needs. We provide an overview of existing practices, specific interventions, strategies, processes, and resources used in schools, further and higher education institutions, and by employers that can account for improved vocational outcomes and/or successful transitions. Conclusions The employment potential of autistic students can be supported by a wide range of interventions many of which are not costly or difficult to implement. They fall into three broad types: remedial interventions that seek to change the autistic individual and how they [inter]act with their environment, adaptions that promote a more inclusive physical environment, and training and awareness raising interventions for others that promote change and support for autistic individuals in the social environment. We speculate on the insights to identify areas for further research. En ligne : https://doi.org/10.1016/j.rasd.2023.102262 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517 [article] Environmental interventions supporting autistic transition-age youth employability: A scoping review [Texte imprimé et/ou numérique] / Mehmet KARAKUS, Auteur ; Filiz POLAT, Auteur . - 102262. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102262 Mots-clés : Autism  Environment  Transition-age youth  Employment  Vocational outcomes Index. décimale : PER Périodiques Résumé : Background Navigating the transition from school to work presents a challenge to many young people, and for autistic youth the challenge can be such that they never make it into employment. A greater understanding of interventions that support this important transition is needed. Method We conducted a scoping review of existing literature focusing on environmental interventions to support transition age youth preparing for employment. We categorized and analyzed the corpus of articles against the "environmental factors' aspect of the International Classification of Functioning, Disability and Health (ICF) published by the World Health Organization. Results The five domains of environmental factors including the physical, social, and attitudinal environment in which people live offer an a priori framework to identify interventions that have been used globally to address autistic individuals' needs. We provide an overview of existing practices, specific interventions, strategies, processes, and resources used in schools, further and higher education institutions, and by employers that can account for improved vocational outcomes and/or successful transitions. Conclusions The employment potential of autistic students can be supported by a wide range of interventions many of which are not costly or difficult to implement. They fall into three broad types: remedial interventions that seek to change the autistic individual and how they [inter]act with their environment, adaptions that promote a more inclusive physical environment, and training and awareness raising interventions for others that promote change and support for autistic individuals in the social environment. We speculate on the insights to identify areas for further research. En ligne : https://doi.org/10.1016/j.rasd.2023.102262 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517

Similar overall expression, but different profiles, of autistic traits, sensory processing, and mental health between young adult males and females / Miranda MCQUARRIE ; Savanah CALTON ; Terisa P. GABRIELSEN in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102263 Titre : Similar overall expression, but different profiles, of autistic traits, sensory processing, and mental health between young adult males and females Type de document : Texte imprimé et/ou numérique Auteurs : Miranda MCQUARRIE, Auteur ; Savanah CALTON, Auteur ; Terisa P. GABRIELSEN, Auteur Article en page(s) : 102263 Langues : Anglais (eng) Mots-clés : Autism  Autistic traits  Sensory processing  Camouflaging  Intolerance of uncertainty  Anxiety  Female  Dimensional Index. décimale : PER Périodiques Résumé : Recent trends suggest that autism is more common in females than traditionally held. Additionally, some argue that females express autistic traits differently than males. Dimensional views of autism could shed light on these issues, especially with regards to understudied behavioral areas, such as sensory processing. We examined autistic traits, sensory processing, anxiety, and related behaviors in a large sample of neurotypical young adult males and females (n = 1122; 556 female; ages 19-26). Participants completed an online survey containing questionnaires related to the above. Between groups statistical analyses, as well as within groups correlations and mediation analyses containing these constructs were then computed. We also carried out a cluster analysis to establish groups with behavioral similarities and estimate within-cluster male/female ratios. Results showed modest differences in the overall expression of autistic traits and sensory processing, if any, between males and females. Conversely, more detailed examination of survey subtests and mediation analyses revealed differing profiles between these groups. Cluster analysis uncovered a group comprised of both males (69.8%) and females (30.2%) who exhibited elevated degrees of autism-related behaviors, suggesting a higher proportion of females than would be predicted by traditional ratios. Taken together, these findings suggest that males and females may not differ as much as previously thought in their general levels of autistic traits or sensory processing, but may present with distinct profiles of such behaviors. These novel results add to our understanding of autistic traits in females and have the potential to positively influence diagnostic and support practices. En ligne : https://doi.org/10.1016/j.rasd.2023.102263 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517 [article] Similar overall expression, but different profiles, of autistic traits, sensory processing, and mental health between young adult males and females [Texte imprimé et/ou numérique] / Miranda MCQUARRIE, Auteur ; Savanah CALTON, Auteur ; Terisa P. GABRIELSEN, Auteur . - 102263. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102263 Mots-clés : Autism  Autistic traits  Sensory processing  Camouflaging  Intolerance of uncertainty  Anxiety  Female  Dimensional Index. décimale : PER Périodiques Résumé : Recent trends suggest that autism is more common in females than traditionally held. Additionally, some argue that females express autistic traits differently than males. Dimensional views of autism could shed light on these issues, especially with regards to understudied behavioral areas, such as sensory processing. We examined autistic traits, sensory processing, anxiety, and related behaviors in a large sample of neurotypical young adult males and females (n = 1122; 556 female; ages 19-26). Participants completed an online survey containing questionnaires related to the above. Between groups statistical analyses, as well as within groups correlations and mediation analyses containing these constructs were then computed. We also carried out a cluster analysis to establish groups with behavioral similarities and estimate within-cluster male/female ratios. Results showed modest differences in the overall expression of autistic traits and sensory processing, if any, between males and females. Conversely, more detailed examination of survey subtests and mediation analyses revealed differing profiles between these groups. Cluster analysis uncovered a group comprised of both males (69.8%) and females (30.2%) who exhibited elevated degrees of autism-related behaviors, suggesting a higher proportion of females than would be predicted by traditional ratios. Taken together, these findings suggest that males and females may not differ as much as previously thought in their general levels of autistic traits or sensory processing, but may present with distinct profiles of such behaviors. These novel results add to our understanding of autistic traits in females and have the potential to positively influence diagnostic and support practices. En ligne : https://doi.org/10.1016/j.rasd.2023.102263 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517

The feasibility and acceptability of AllPlay Dance for autistic children: A pilot randomised controlled trial / Olivia MILLARD ; Nicole PAPADOPOULOS ; Bethany D. DEVENISH ; Susannah BELLOWS ; Ana MANTILLA ; Jane MCGILLIVRAY ; Nicole J. RINEHART in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102271 Titre : The feasibility and acceptability of AllPlay Dance for autistic children: A pilot randomised controlled trial Type de document : Texte imprimé et/ou numérique Auteurs : Olivia MILLARD, Auteur ; Nicole PAPADOPOULOS, Auteur ; Bethany D. DEVENISH, Auteur ; Susannah BELLOWS, Auteur ; Ana MANTILLA, Auteur ; Jane MCGILLIVRAY, Auteur ; Nicole J. RINEHART, Auteur Article en page(s) : 102271 Langues : Anglais (eng) Mots-clés : Autism  Dance  Community intervention  Motor skills Index. décimale : PER Périodiques Résumé : Purpose Few studies have explored the potential for community dance programs to act as a feasible and acceptable avenue for improving the physical, social, and mental health outcomes of autistic children. This randomised waitlist-controlled pilot trial examined the feasibility, acceptability and preliminary efficacy of the classical/contemporary AllPlay Dance program for autistic children. Methods Twenty-seven autistic children aged 7-12 were randomised to either the intervention group or waitlist control group. Primary outcomes were the acceptability and feasibility of the program, as measured by general study metrics (e.g., enrolment rate, drop out, session attendance) and the participants' subjective ratings of their experiences (e.g., enjoyment, willingness to do more sessions/recommend the program, etc.). Secondary outcomes included changes in children?s motor proficiency, quality of life, and social, emotional and behavioural functioning. Results The AllPlay Dance program was feasible to conduct and acceptable to young autistic dancers, their parents, and the elite dancers/buddies whose role was to support their participation. There were also promising trends towards improvement in aspects of motor functioning (i.e., aiming and catching). Conclusion Overall, the findings support the need to conduct a full-scale randomised-controlled trial to confirm the potential gains that this inclusive and creative community-based activity can offer autistic children. En ligne : https://doi.org/10.1016/j.rasd.2023.102271 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517 [article] The feasibility and acceptability of AllPlay Dance for autistic children: A pilot randomised controlled trial [Texte imprimé et/ou numérique] / Olivia MILLARD, Auteur ; Nicole PAPADOPOULOS, Auteur ; Bethany D. DEVENISH, Auteur ; Susannah BELLOWS, Auteur ; Ana MANTILLA, Auteur ; Jane MCGILLIVRAY, Auteur ; Nicole J. RINEHART, Auteur . - 102271. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102271 Mots-clés : Autism  Dance  Community intervention  Motor skills Index. décimale : PER Périodiques Résumé : Purpose Few studies have explored the potential for community dance programs to act as a feasible and acceptable avenue for improving the physical, social, and mental health outcomes of autistic children. This randomised waitlist-controlled pilot trial examined the feasibility, acceptability and preliminary efficacy of the classical/contemporary AllPlay Dance program for autistic children. Methods Twenty-seven autistic children aged 7-12 were randomised to either the intervention group or waitlist control group. Primary outcomes were the acceptability and feasibility of the program, as measured by general study metrics (e.g., enrolment rate, drop out, session attendance) and the participants' subjective ratings of their experiences (e.g., enjoyment, willingness to do more sessions/recommend the program, etc.). Secondary outcomes included changes in children?s motor proficiency, quality of life, and social, emotional and behavioural functioning. Results The AllPlay Dance program was feasible to conduct and acceptable to young autistic dancers, their parents, and the elite dancers/buddies whose role was to support their participation. There were also promising trends towards improvement in aspects of motor functioning (i.e., aiming and catching). Conclusion Overall, the findings support the need to conduct a full-scale randomised-controlled trial to confirm the potential gains that this inclusive and creative community-based activity can offer autistic children. En ligne : https://doi.org/10.1016/j.rasd.2023.102271 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517

The experience of anxiety for autistic children and young people: A thematic synthesis review / Caroline BOND in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102274 Titre : The experience of anxiety for autistic children and young people: A thematic synthesis review Type de document : Texte imprimé et/ou numérique Auteurs : Caroline BOND, Auteur Article en page(s) : 102274 Langues : Anglais (eng) Mots-clés : Autism  Neurodiversity  Anxiety  Perspectives  Children and young people  Thematic synthesis literature review Index. décimale : PER Périodiques Résumé : Background Anxiety is a commonly co-occurring mental health condition for autistic children and young people. Literature indicates a fractured conceptualisation of the construct of anxiety and measurement tools may be insensitive to unique autistic presentations. The neurodiversity paradigm calls for a shift towards qualitative research methodologies situated within everyday realities. The purpose of this review is to synthesise experiences of anxiety for autistic children and young people from their perspective and the viewpoint of parents. Method Informed by PRISMA guidelines, this systematic review searched for empirical studies published between January 2012 and January 2022 reporting on the experience of anxiety for autistic children and young people aged between 3 and 18. Of the 473 studies screened for inclusion, 10 studies fulfilled inclusion and quality appraisal criteria. Data were analysed using thematic synthesis. Findings Findings highlighted differences in the ways children and young people and their parents conceptualise anxiety in autism. Parents tended to report behavioural presentations of children and young people's anxiety while young people provided insight into their cognitive processes and emotions. Lived experiences provided unique insights into the role of neurotypical environments in state anxiety and how differences in perception of time can also mediate young people?s experiences of anxiety. Conclusions Implications for policy and practice include the priority for authentically eliciting the views of cognitively-able and less-able autistic children and young people with cooccurring anxiety across contexts in assessment and research. This review highlights the need for significant investment in social environments that seek to minimise anxiety in neurodiverse children and young people. En ligne : https://doi.org/10.1016/j.rasd.2023.102274 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517 [article] The experience of anxiety for autistic children and young people: A thematic synthesis review [Texte imprimé et/ou numérique] / Caroline BOND, Auteur . - 102274. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102274 Mots-clés : Autism  Neurodiversity  Anxiety  Perspectives  Children and young people  Thematic synthesis literature review Index. décimale : PER Périodiques Résumé : Background Anxiety is a commonly co-occurring mental health condition for autistic children and young people. Literature indicates a fractured conceptualisation of the construct of anxiety and measurement tools may be insensitive to unique autistic presentations. The neurodiversity paradigm calls for a shift towards qualitative research methodologies situated within everyday realities. The purpose of this review is to synthesise experiences of anxiety for autistic children and young people from their perspective and the viewpoint of parents. Method Informed by PRISMA guidelines, this systematic review searched for empirical studies published between January 2012 and January 2022 reporting on the experience of anxiety for autistic children and young people aged between 3 and 18. Of the 473 studies screened for inclusion, 10 studies fulfilled inclusion and quality appraisal criteria. Data were analysed using thematic synthesis. Findings Findings highlighted differences in the ways children and young people and their parents conceptualise anxiety in autism. Parents tended to report behavioural presentations of children and young people's anxiety while young people provided insight into their cognitive processes and emotions. Lived experiences provided unique insights into the role of neurotypical environments in state anxiety and how differences in perception of time can also mediate young people?s experiences of anxiety. Conclusions Implications for policy and practice include the priority for authentically eliciting the views of cognitively-able and less-able autistic children and young people with cooccurring anxiety across contexts in assessment and research. This review highlights the need for significant investment in social environments that seek to minimise anxiety in neurodiverse children and young people. En ligne : https://doi.org/10.1016/j.rasd.2023.102274 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517

Barriers to an autistic identity: How RRBs may contribute to the underdiagnosis of females / Aparajita RAO ; Erin Stephanie Misato MATSUBA ; Natalie RUSSO in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102275 Titre : Barriers to an autistic identity: How RRBs may contribute to the underdiagnosis of females Type de document : Texte imprimé et/ou numérique Auteurs : Aparajita RAO, Auteur ; Erin Stephanie Misato MATSUBA, Auteur ; Natalie RUSSO, Auteur Article en page(s) : 102275 Langues : Anglais (eng) Mots-clés : Autistic identity, females, RRBs  Sensory  Diagnosis Index. décimale : PER Périodiques Résumé : Background Autistic females are frequently underdiagnosed, misdiagnosed, and/or diagnosed later in life. Restricted and Repetitive Behaviors (RRBs) are increasingly critical for diagnosis and yet are commonly rated lower in females. Whether this reflects genuinely lower levels of these traits, or if female-typical RRBs have a different phenotypic presentation that may not register on current quantitative measurement tools is unclear. Methods Twenty-one autistic females and 21 autistic males matched on chronological age and FSIQ completed the AQ, ADOS-2, and ADI-R. Items from the ADOS-2 and ADI-R were selected that were relevant to the four area s of restricted and repetitive behavior in the DSM-5 diagnostic criteria of autism. Using a mixed-methods analytical approach, scores and comments on these measures were compared between sexes to better characterize RRBs in autistic females. Results There were no sex differences on the AQ, which broadly assesses autistic traits. When analyzed by the four DSM-5 RRB criteria, there were no sex differences on the ADI-R when using traditional algorithm scoring that narrows questions down to those that are more sensitive and specific in capturing autism in research samples with a high proportion of males. When incorporating additional items relevant to the DSM-5 to identify sex differences in a broader pool of items, females scored higher on stereotyped movements and speech. Females also engaged in more sensory behaviors during the ADOS-2. Qualitative analyses indicated that females were more likely to engage in stereotyped body rocking and spinning, stereotyped behaviors when anxious, to show major reactions to changes, repetitive language including listing and counting, and sensory behaviors, especially in the tactile domain. Conclusion Exploratory findings highlight sex differences in RRBs that may help enhance diagnostic clarity for females. Higher tactile sensory behaviors in females suggests there may be increased diagnostic sensitivity for females with the updated DSM-5 that now includes sensory components as part of the diagnostic criteria. En ligne : https://doi.org/10.1016/j.rasd.2023.102275 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517 [article] Barriers to an autistic identity: How RRBs may contribute to the underdiagnosis of females [Texte imprimé et/ou numérique] / Aparajita RAO, Auteur ; Erin Stephanie Misato MATSUBA, Auteur ; Natalie RUSSO, Auteur . - 102275. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102275 Mots-clés : Autistic identity, females, RRBs  Sensory  Diagnosis Index. décimale : PER Périodiques Résumé : Background Autistic females are frequently underdiagnosed, misdiagnosed, and/or diagnosed later in life. Restricted and Repetitive Behaviors (RRBs) are increasingly critical for diagnosis and yet are commonly rated lower in females. Whether this reflects genuinely lower levels of these traits, or if female-typical RRBs have a different phenotypic presentation that may not register on current quantitative measurement tools is unclear. Methods Twenty-one autistic females and 21 autistic males matched on chronological age and FSIQ completed the AQ, ADOS-2, and ADI-R. Items from the ADOS-2 and ADI-R were selected that were relevant to the four area s of restricted and repetitive behavior in the DSM-5 diagnostic criteria of autism. Using a mixed-methods analytical approach, scores and comments on these measures were compared between sexes to better characterize RRBs in autistic females. Results There were no sex differences on the AQ, which broadly assesses autistic traits. When analyzed by the four DSM-5 RRB criteria, there were no sex differences on the ADI-R when using traditional algorithm scoring that narrows questions down to those that are more sensitive and specific in capturing autism in research samples with a high proportion of males. When incorporating additional items relevant to the DSM-5 to identify sex differences in a broader pool of items, females scored higher on stereotyped movements and speech. Females also engaged in more sensory behaviors during the ADOS-2. Qualitative analyses indicated that females were more likely to engage in stereotyped body rocking and spinning, stereotyped behaviors when anxious, to show major reactions to changes, repetitive language including listing and counting, and sensory behaviors, especially in the tactile domain. Conclusion Exploratory findings highlight sex differences in RRBs that may help enhance diagnostic clarity for females. Higher tactile sensory behaviors in females suggests there may be increased diagnostic sensitivity for females with the updated DSM-5 that now includes sensory components as part of the diagnostic criteria. En ligne : https://doi.org/10.1016/j.rasd.2023.102275 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517

Evaluating Autism diagnosis agreement between primary care physicians/practitioners and experts through ECHO Autism STAT / Rachel BROWN ; Valeria NANCLARES-NOGUÉS ; Melinda ODUM ; Amanda BARRETT ; Micah O. MAZUREK ; Kristin SOHL in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102276 Titre : Evaluating Autism diagnosis agreement between primary care physicians/practitioners and experts through ECHO Autism STAT Type de document : Texte imprimé et/ou numérique Auteurs : Rachel BROWN, Auteur ; Valeria NANCLARES-NOGUÉS, Auteur ; Melinda ODUM, Auteur ; Amanda BARRETT, Auteur ; Micah O. MAZUREK, Auteur ; Kristin SOHL, Auteur Article en page(s) : 102276 Langues : Anglais (eng) Mots-clés : Autism  Autism spectrum disorder  Primary care provider  Diagnosis  ECHO Autism Index. décimale : PER Périodiques Résumé : Background Even though early intervention leads to improved outcomes for children with autism spectrum disorder (ASD), delays in diagnosis can have an impact on both children and families. ASD diagnostic practices have significantly evolved over time, in part, because of the lack of specialists to meet the demand. ECHO Autism STAT is one innovative model that increased the capacity of community primary care providers (PCPs) to reliably diagnose ASD within their own practices via hands-on training and virtual guidance and support from ASD specialists. The current study evaluated PCPs agreement with ECHO Autism experts in making independent clinical decisions related to ASD diagnosis in unambiguous cases. Method After obtaining reliability on the STAT and attending 6 mo of ECHO Autism sessions, PCPs agreement with expert impressions was evaluated for (a) diagnosing unambiguous ASD and (b) identifying symptoms that met DSM-5 criteria. Results The proportion of cases that achieved the highest PCP agreement score with ASD experts for overall ASD diagnostic impressions was 90% across all cases, 94% across unambiguous cases, and 84% across more complex cases. PCP agreement for DSM-5 symptom impressions was 79%, 87%, and 66% across all, unambiguous, and more complex cases, respectively. Results were significant for unambiguous cases when compared to more complex cases. Conclusions PCPs can develop clinical expertise in the evaluation and diagnosis of young children with unambiguous ASD that is accurate and reliable. Development of this expertise can expand access for community-based diagnosis that is critical for early detection of ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102276 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517 [article] Evaluating Autism diagnosis agreement between primary care physicians/practitioners and experts through ECHO Autism STAT [Texte imprimé et/ou numérique] / Rachel BROWN, Auteur ; Valeria NANCLARES-NOGUÉS, Auteur ; Melinda ODUM, Auteur ; Amanda BARRETT, Auteur ; Micah O. MAZUREK, Auteur ; Kristin SOHL, Auteur . - 102276. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102276 Mots-clés : Autism  Autism spectrum disorder  Primary care provider  Diagnosis  ECHO Autism Index. décimale : PER Périodiques Résumé : Background Even though early intervention leads to improved outcomes for children with autism spectrum disorder (ASD), delays in diagnosis can have an impact on both children and families. ASD diagnostic practices have significantly evolved over time, in part, because of the lack of specialists to meet the demand. ECHO Autism STAT is one innovative model that increased the capacity of community primary care providers (PCPs) to reliably diagnose ASD within their own practices via hands-on training and virtual guidance and support from ASD specialists. The current study evaluated PCPs agreement with ECHO Autism experts in making independent clinical decisions related to ASD diagnosis in unambiguous cases. Method After obtaining reliability on the STAT and attending 6 mo of ECHO Autism sessions, PCPs agreement with expert impressions was evaluated for (a) diagnosing unambiguous ASD and (b) identifying symptoms that met DSM-5 criteria. Results The proportion of cases that achieved the highest PCP agreement score with ASD experts for overall ASD diagnostic impressions was 90% across all cases, 94% across unambiguous cases, and 84% across more complex cases. PCP agreement for DSM-5 symptom impressions was 79%, 87%, and 66% across all, unambiguous, and more complex cases, respectively. Results were significant for unambiguous cases when compared to more complex cases. Conclusions PCPs can develop clinical expertise in the evaluation and diagnosis of young children with unambiguous ASD that is accurate and reliable. Development of this expertise can expand access for community-based diagnosis that is critical for early detection of ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102276 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517

Self-reported memory of autistic young adults and associated real-world outcomes / Goldie A. MCQUAID ; Gregory L. WALLACE ; Nancy Raitano LEE in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102277 Titre : Self-reported memory of autistic young adults and associated real-world outcomes Type de document : Texte imprimé et/ou numérique Auteurs : Goldie A. MCQUAID, Auteur ; Gregory L. WALLACE, Auteur ; Nancy Raitano LEE, Auteur Article en page(s) : 102277 Langues : Anglais (eng) Mots-clés : Autism  Prospective memory  Retrospective memory  Activities of daily living  Vocational outcomes Index. décimale : PER Périodiques Résumé : Purpose Although autistic adults have demonstrated weaker memory performance on lab-based measures in comparison to neurotypical peers, research on self-reported memory abilities in this group is scarce. Shedding light on memory abilities of autistic adults is important, as memory difficulties may impact daily living outcomes, an area of difficulty for autistic individuals. Thus, the current study aimed to characterize the self-reported memory complaints of a large sample of autistic adults in comparison to neurotypical adults. Methods This study included data from 396 autistic young adults and 396 neurotypical young adults between the ages of 18 and 39 years and with similar background characteristics. Autistic adults were recruited from the Simons Powering Autism Research (SPARK) participant registry, and data from neurotypical adults were obtained from a large-scale internet study. The responses to the Prospective and Retrospective Memory Questionnaire were compared by diagnostic group, and within the autistic group, relations between memory complaints and real-world outcomes (activities of daily living [ADLs] and postsecondary employment and educational activities) were examined. Results The results indicated that young autistic adults reported greater memory problems than their neurotypical peers, regardless of memory type, and autistic adults reported a comparable pattern of complaints to their neurotypical peers (i.e., greater prospective memory complaints in comparison to retrospective memory complaints). Additionally, we found a negative association between memory complaints and outcomes (i.e., greater memory complaints were associated with less independence in ADLs and less favorable postsecondary outcomes). Conclusion The significant association between subjective memory complaints and real-world outcomes suggests that memory abilities are an important contributor to daily living skills and post-secondary outcomes among autistic adults and could represent a target for future intervention development. En ligne : https://doi.org/10.1016/j.rasd.2023.102277 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517 [article] Self-reported memory of autistic young adults and associated real-world outcomes [Texte imprimé et/ou numérique] / Goldie A. MCQUAID, Auteur ; Gregory L. WALLACE, Auteur ; Nancy Raitano LEE, Auteur . - 102277. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102277 Mots-clés : Autism  Prospective memory  Retrospective memory  Activities of daily living  Vocational outcomes Index. décimale : PER Périodiques Résumé : Purpose Although autistic adults have demonstrated weaker memory performance on lab-based measures in comparison to neurotypical peers, research on self-reported memory abilities in this group is scarce. Shedding light on memory abilities of autistic adults is important, as memory difficulties may impact daily living outcomes, an area of difficulty for autistic individuals. Thus, the current study aimed to characterize the self-reported memory complaints of a large sample of autistic adults in comparison to neurotypical adults. Methods This study included data from 396 autistic young adults and 396 neurotypical young adults between the ages of 18 and 39 years and with similar background characteristics. Autistic adults were recruited from the Simons Powering Autism Research (SPARK) participant registry, and data from neurotypical adults were obtained from a large-scale internet study. The responses to the Prospective and Retrospective Memory Questionnaire were compared by diagnostic group, and within the autistic group, relations between memory complaints and real-world outcomes (activities of daily living [ADLs] and postsecondary employment and educational activities) were examined. Results The results indicated that young autistic adults reported greater memory problems than their neurotypical peers, regardless of memory type, and autistic adults reported a comparable pattern of complaints to their neurotypical peers (i.e., greater prospective memory complaints in comparison to retrospective memory complaints). Additionally, we found a negative association between memory complaints and outcomes (i.e., greater memory complaints were associated with less independence in ADLs and less favorable postsecondary outcomes). Conclusion The significant association between subjective memory complaints and real-world outcomes suggests that memory abilities are an important contributor to daily living skills and post-secondary outcomes among autistic adults and could represent a target for future intervention development. En ligne : https://doi.org/10.1016/j.rasd.2023.102277 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517

Exploring the relationship between COVID-19 and autistic adults' community participation: Findings from a two-timepoint longitudinal study / Mark S. SALZER ; Alec BECKER ; David J. VANNESS ; Brian K. LEE ; Dylan COOPER ; Jonas VENTIMIGLIA ; Lindsay L. SHEA in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102278 Titre : Exploring the relationship between COVID-19 and autistic adults' community participation: Findings from a two-timepoint longitudinal study Type de document : Texte imprimé et/ou numérique Auteurs : Mark S. SALZER, Auteur ; Alec BECKER, Auteur ; David J. VANNESS, Auteur ; Brian K. LEE, Auteur ; Dylan COOPER, Auteur ; Jonas VENTIMIGLIA, Auteur ; Lindsay L. SHEA, Auteur Article en page(s) : 102278 Langues : Anglais (eng) Mots-clés : Autism  COVID-19  Community participation  Autistic adults Index. décimale : PER Périodiques Résumé : Background The COVID-19 pandemic has resulted in a continuum of changes in communities that have impacted the lives and health of millions of autistic people. Method To identify community participation changes during COVID-19, we conducted a two-timepoint (2018 and 2022) longitudinal quantitative study involving 116 autistic adults in Pennsylvania to investigate the impact of the pandemic on their community participation. Community participation was measured by the Temple University Community Participation Measure, and the impact of the pandemic was measured by a series of factors related to the COVID-19 pandemic (e.g., healthcare access, transportation, safety, etc.). Results Results of paired sample t-tests did not show changes in participants' total days of participation over the last 30 days, the total number of activities, or percentages of all activities participants considered important and participated in (i.e., breadth ratio) between the timepoints. However, the percentage of activities that were important to participants and in which they reported engaging as much as they wanted to (i.e., sufficiency ratio) reduced significantly. When examining participation outcomes and COVID-19 impact, we found that multiple participation outcomes (i.e., number of activities, breadth ratio, and sufficiency ratio) were negatively associated with the COVID-19 impact. Conclusion Results suggest that the COVID-19 impacts on autistic adults are variable, with those reporting a more significant impact also reporting a significantly lower level of participation. These findings emphasize the importance of individualized planning to support autistic adults to maintain or regain participation in their preferred activities during the pandemic and beyond. En ligne : https://doi.org/10.1016/j.rasd.2023.102278 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517 [article] Exploring the relationship between COVID-19 and autistic adults' community participation: Findings from a two-timepoint longitudinal study [Texte imprimé et/ou numérique] / Mark S. SALZER, Auteur ; Alec BECKER, Auteur ; David J. VANNESS, Auteur ; Brian K. LEE, Auteur ; Dylan COOPER, Auteur ; Jonas VENTIMIGLIA, Auteur ; Lindsay L. SHEA, Auteur . - 102278. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102278 Mots-clés : Autism  COVID-19  Community participation  Autistic adults Index. décimale : PER Périodiques Résumé : Background The COVID-19 pandemic has resulted in a continuum of changes in communities that have impacted the lives and health of millions of autistic people. Method To identify community participation changes during COVID-19, we conducted a two-timepoint (2018 and 2022) longitudinal quantitative study involving 116 autistic adults in Pennsylvania to investigate the impact of the pandemic on their community participation. Community participation was measured by the Temple University Community Participation Measure, and the impact of the pandemic was measured by a series of factors related to the COVID-19 pandemic (e.g., healthcare access, transportation, safety, etc.). Results Results of paired sample t-tests did not show changes in participants' total days of participation over the last 30 days, the total number of activities, or percentages of all activities participants considered important and participated in (i.e., breadth ratio) between the timepoints. However, the percentage of activities that were important to participants and in which they reported engaging as much as they wanted to (i.e., sufficiency ratio) reduced significantly. When examining participation outcomes and COVID-19 impact, we found that multiple participation outcomes (i.e., number of activities, breadth ratio, and sufficiency ratio) were negatively associated with the COVID-19 impact. Conclusion Results suggest that the COVID-19 impacts on autistic adults are variable, with those reporting a more significant impact also reporting a significantly lower level of participation. These findings emphasize the importance of individualized planning to support autistic adults to maintain or regain participation in their preferred activities during the pandemic and beyond. En ligne : https://doi.org/10.1016/j.rasd.2023.102278 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517

Examining the feasibility and effectiveness of PEERS for adolescents via telehealth during the COVID-19 pandemic / Connor PETRICEK ; Morgan HAGA ; Samantha SMALLEY ; Katherine PELLETIER ; Nimco ESSA ; Rebekah L. HUDOCK in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102279 Titre : Examining the feasibility and effectiveness of PEERS for adolescents via telehealth during the COVID-19 pandemic Type de document : Texte imprimé et/ou numérique Auteurs : Connor PETRICEK, Auteur ; Morgan HAGA, Auteur ; Samantha SMALLEY, Auteur ; Katherine PELLETIER, Auteur ; Nimco ESSA, Auteur ; Rebekah L. HUDOCK, Auteur Article en page(s) : 102279 Langues : Anglais (eng) Mots-clés : Social skills group  Telehealth  PEERS  Feasibility  Outcome Index. décimale : PER Périodiques Résumé : Background The PEERS program is an evidence-based social skills intervention focusing on skills related to making and keeping friends as well as managing conflict and rejections. Because of the COVID-19 pandemic, social skills interventions have been moving to virtual settings, including PEERS; however, limited research on the feasibility and efficacy of telehealth group therapy has been done. Method Thirty-four families were referred through an autism specialty clinic to complete the online PEERS program, and fourteen families completed measures of social skills, emotional and behavioral symptoms, and executive functioning before and after participating in the program. Results The outcomes revealed significant improvements in participants' social skills knowledge, social communication, social motivation, and aspects of executive functioning. Participants also reported being satisfied with the online format, further supporting the hypothesis that the modified PEERS program, held virtually, is feasible and effective. Conclusion Our results support that the telehealth PEERS program offers a good alternative to the in-person modality and other social skills programs, especially for families who have difficulty accessing evidence-based programming for autistic adolescents due to geographical or transportation limitations as well as for families who prefer the convenience of participating in this program virtually. En ligne : https://doi.org/10.1016/j.rasd.2023.102279 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517 [article] Examining the feasibility and effectiveness of PEERS for adolescents via telehealth during the COVID-19 pandemic [Texte imprimé et/ou numérique] / Connor PETRICEK, Auteur ; Morgan HAGA, Auteur ; Samantha SMALLEY, Auteur ; Katherine PELLETIER, Auteur ; Nimco ESSA, Auteur ; Rebekah L. HUDOCK, Auteur . - 102279. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102279 Mots-clés : Social skills group  Telehealth  PEERS  Feasibility  Outcome Index. décimale : PER Périodiques Résumé : Background The PEERS program is an evidence-based social skills intervention focusing on skills related to making and keeping friends as well as managing conflict and rejections. Because of the COVID-19 pandemic, social skills interventions have been moving to virtual settings, including PEERS; however, limited research on the feasibility and efficacy of telehealth group therapy has been done. Method Thirty-four families were referred through an autism specialty clinic to complete the online PEERS program, and fourteen families completed measures of social skills, emotional and behavioral symptoms, and executive functioning before and after participating in the program. Results The outcomes revealed significant improvements in participants' social skills knowledge, social communication, social motivation, and aspects of executive functioning. Participants also reported being satisfied with the online format, further supporting the hypothesis that the modified PEERS program, held virtually, is feasible and effective. Conclusion Our results support that the telehealth PEERS program offers a good alternative to the in-person modality and other social skills programs, especially for families who have difficulty accessing evidence-based programming for autistic adolescents due to geographical or transportation limitations as well as for families who prefer the convenience of participating in this program virtually. En ligne : https://doi.org/10.1016/j.rasd.2023.102279 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517

Siblings and social interaction development of individuals with ASD: A systematic review / Moon Young Savana BAK ; LeAnne D. JOHNSON ; Lalinne S. BELL ; Natalie G. DUMAS in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102280 Titre : Siblings and social interaction development of individuals with ASD: A systematic review Type de document : Texte imprimé et/ou numérique Auteurs : Moon Young Savana BAK, Auteur ; LeAnne D. JOHNSON, Auteur ; Lalinne S. BELL, Auteur ; Natalie G. DUMAS, Auteur Article en page(s) : 102280 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Siblings  Social interaction Index. décimale : PER Périodiques Résumé : Sibling relationships may play a unique role in the social development of individuals with autism spectrum disorder (ASD). Research suggests that the involvement of siblings within focused intervention contexts can be beneficial for the social skills improvement of individuals with ASD. However, compared to research focusing on the impact of individuals with ASD on their siblings, there is relatively little research about the influence of siblings on the social interaction development of individuals with ASD. As an important exploratory step, this systematic review aims to summarize existing literature that investigated siblings relative to the development of social interactions of individuals with ASD. A total of 105 studies were included in this review regarding social interaction development of siblings and individuals with ASD, and a subset of 24 studies that focused on the influence of siblings on individuals with ASD were further analyzed. The results suggested that the majority of included studies (77.14%) focused on the social interaction outcomes of the siblings rather than individuals with ASD with variability regarding studies' variables of interest. Implications and future directions are also discussed. En ligne : https://doi.org/10.1016/j.rasd.2023.102280 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=518 [article] Siblings and social interaction development of individuals with ASD: A systematic review [Texte imprimé et/ou numérique] / Moon Young Savana BAK, Auteur ; LeAnne D. JOHNSON, Auteur ; Lalinne S. BELL, Auteur ; Natalie G. DUMAS, Auteur . - 102280. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102280 Mots-clés : Autism spectrum disorder  Siblings  Social interaction Index. décimale : PER Périodiques Résumé : Sibling relationships may play a unique role in the social development of individuals with autism spectrum disorder (ASD). Research suggests that the involvement of siblings within focused intervention contexts can be beneficial for the social skills improvement of individuals with ASD. However, compared to research focusing on the impact of individuals with ASD on their siblings, there is relatively little research about the influence of siblings on the social interaction development of individuals with ASD. As an important exploratory step, this systematic review aims to summarize existing literature that investigated siblings relative to the development of social interactions of individuals with ASD. A total of 105 studies were included in this review regarding social interaction development of siblings and individuals with ASD, and a subset of 24 studies that focused on the influence of siblings on individuals with ASD were further analyzed. The results suggested that the majority of included studies (77.14%) focused on the social interaction outcomes of the siblings rather than individuals with ASD with variability regarding studies' variables of interest. Implications and future directions are also discussed. En ligne : https://doi.org/10.1016/j.rasd.2023.102280 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=518

Preliminary efficacy of a transition training program for autistic adolescents / Andrea VALDEZ in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102281 Titre : Preliminary efficacy of a transition training program for autistic adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Andrea VALDEZ, Auteur Article en page(s) : 102281 Langues : Anglais (eng) Mots-clés : Adolescents  Transition outcomes  Autism  Pre employment skills  Sensory processing Index. décimale : PER Périodiques Résumé : Purpose Young autistic adults experience poor transition outcomes in the area of employment. With reduced opportunities to develop work skills, there are also reduced opportunities for socialization, independence and experiences of success. Thus, there is a need for transition planning programs for autistic adolescents and youth. Method This pilot study employed two complementary methodologies. A non-concurrent multiple baseline study using a visual analog scale (VAS) as the repeated measure was employed. Pre post measures were also collected from the parent participant and student participants' perspective using two standardized measures. The thirteen student participants, age 12-18 years all had a diagnosis of autism. Seven parent and 6 adolescents completed the pretest and posttest measures. The Project FUSE, Fostering Unlimited Success and Empowerment intervention program was a collaboration between two organizations, designed to build skills in the workplace, while also addressing sensory processing, arousal regulation and establishing productive relationships. Visual analog Results The three VAS questions most sensitive to change were related to prideful behavior, developing work skills and safety in tool use. There was no significant change in the Transition Behavior Scale: Third Edition. The Culture Free Self Esteem Inventories, Third Edition showed significant, meaningful change in the Global Self Esteem Quotient, and Academic Self -Esteem. Conclusion Project FUSE was found to be a potentially efficacious method for developing pre-employment skills in autistic youth. The data suggest that the programming had a positive influence on developing work skills, tool safety, and self-esteem. En ligne : https://doi.org/10.1016/j.rasd.2023.102281 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=518 [article] Preliminary efficacy of a transition training program for autistic adolescents [Texte imprimé et/ou numérique] / Andrea VALDEZ, Auteur . - 102281. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102281 Mots-clés : Adolescents  Transition outcomes  Autism  Pre employment skills  Sensory processing Index. décimale : PER Périodiques Résumé : Purpose Young autistic adults experience poor transition outcomes in the area of employment. With reduced opportunities to develop work skills, there are also reduced opportunities for socialization, independence and experiences of success. Thus, there is a need for transition planning programs for autistic adolescents and youth. Method This pilot study employed two complementary methodologies. A non-concurrent multiple baseline study using a visual analog scale (VAS) as the repeated measure was employed. Pre post measures were also collected from the parent participant and student participants' perspective using two standardized measures. The thirteen student participants, age 12-18 years all had a diagnosis of autism. Seven parent and 6 adolescents completed the pretest and posttest measures. The Project FUSE, Fostering Unlimited Success and Empowerment intervention program was a collaboration between two organizations, designed to build skills in the workplace, while also addressing sensory processing, arousal regulation and establishing productive relationships. Visual analog Results The three VAS questions most sensitive to change were related to prideful behavior, developing work skills and safety in tool use. There was no significant change in the Transition Behavior Scale: Third Edition. The Culture Free Self Esteem Inventories, Third Edition showed significant, meaningful change in the Global Self Esteem Quotient, and Academic Self -Esteem. Conclusion Project FUSE was found to be a potentially efficacious method for developing pre-employment skills in autistic youth. The data suggest that the programming had a positive influence on developing work skills, tool safety, and self-esteem. En ligne : https://doi.org/10.1016/j.rasd.2023.102281 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=518

Preliminary analysis of a clinical trial of children with autism spectrum disorder treated with DHA-rich marine Schizochytrium sp. oil and multi-vitamin/mineral complex / Maria Aparecida Baptista de OLIVEIRA ; Fernando Augusto Lima MARSON ; Juliana Mozer SCIANI in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102282 Titre : Preliminary analysis of a clinical trial of children with autism spectrum disorder treated with DHA-rich marine Schizochytrium sp. oil and multi-vitamin/mineral complex Type de document : Texte imprimé et/ou numérique Auteurs : Maria Aparecida Baptista de OLIVEIRA, Auteur ; Fernando Augusto Lima MARSON, Auteur ; Juliana Mozer SCIANI, Auteur Article en page(s) : 102282 Langues : Anglais (eng) Mots-clés : Autism  Children  Docosahexaenoic acid  Multi-vitamin & mineral complex  Clinical trial Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder (ASD) is a syndrome characterized by alterations in social interaction and communication, frequently associated with stereotyped patterns, such as repetitive behavior. Inflammation and oxidative stress are frequently observed in patients, and natural products that control these aspects can be an alternative for ASD treatment. Method: In this prospective case series study, we administered in 2-12 years-old children (n = 12) with severe ASD a commercial extract of marine Schizochytrium sp. oil, composed by 200 mg DHA and 2 mg eicosapentaenoic acid, associated to a multi-vitamin/mineral complex, daily for 12 weeks. Patients were evaluated by Childhood Autism Rating Scale (CARS) and Adaptive Behavior Assessment System Third Edition (ABAS-3) scales before and after the treatment, and had the urine analyzed. Results: Values obtained from CARS, general adaptive composite and social domains from ABAS-3 were statistically different after treatment. Although not statistically significant, conceptual and practical domains from ABAS-3 had the score increased in several patients after the intervention. Among these domains, communication and visual contact improved in all patients, and vocabulary, interaction, feeding, and food selectivity were enhanced in some of them. The total antioxidant capacity in urine increased after treatment, as well as some metabolites, like amino acids, which were exclusive in all patient?s urine after the administration of the product. Conclusions: These preliminary data show that the continuous use of marine Schizochytrium sp. oil and multi-vitamin/mineral complex can help control characteristic symptoms of ASD in children. En ligne : https://doi.org/10.1016/j.rasd.2023.102282 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=518 [article] Preliminary analysis of a clinical trial of children with autism spectrum disorder treated with DHA-rich marine Schizochytrium sp. oil and multi-vitamin/mineral complex [Texte imprimé et/ou numérique] / Maria Aparecida Baptista de OLIVEIRA, Auteur ; Fernando Augusto Lima MARSON, Auteur ; Juliana Mozer SCIANI, Auteur . - 102282. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102282 Mots-clés : Autism  Children  Docosahexaenoic acid  Multi-vitamin & mineral complex  Clinical trial Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder (ASD) is a syndrome characterized by alterations in social interaction and communication, frequently associated with stereotyped patterns, such as repetitive behavior. Inflammation and oxidative stress are frequently observed in patients, and natural products that control these aspects can be an alternative for ASD treatment. Method: In this prospective case series study, we administered in 2-12 years-old children (n = 12) with severe ASD a commercial extract of marine Schizochytrium sp. oil, composed by 200 mg DHA and 2 mg eicosapentaenoic acid, associated to a multi-vitamin/mineral complex, daily for 12 weeks. Patients were evaluated by Childhood Autism Rating Scale (CARS) and Adaptive Behavior Assessment System Third Edition (ABAS-3) scales before and after the treatment, and had the urine analyzed. Results: Values obtained from CARS, general adaptive composite and social domains from ABAS-3 were statistically different after treatment. Although not statistically significant, conceptual and practical domains from ABAS-3 had the score increased in several patients after the intervention. Among these domains, communication and visual contact improved in all patients, and vocabulary, interaction, feeding, and food selectivity were enhanced in some of them. The total antioxidant capacity in urine increased after treatment, as well as some metabolites, like amino acids, which were exclusive in all patient?s urine after the administration of the product. Conclusions: These preliminary data show that the continuous use of marine Schizochytrium sp. oil and multi-vitamin/mineral complex can help control characteristic symptoms of ASD in children. En ligne : https://doi.org/10.1016/j.rasd.2023.102282 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=518

"That he won't experience life like he should": Exploring worries of family caregivers of transition-age autistic youth / Grazia DIPIERRO ; Caroline Duke CHAIKIN ; Rita OBEID ; Kristen A. BERG ; Karen J. ISHLER in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102283 Titre : "That he won't experience life like he should": Exploring worries of family caregivers of transition-age autistic youth Type de document : Texte imprimé et/ou numérique Auteurs : Grazia DIPIERRO, Auteur ; Caroline Duke CHAIKIN, Auteur ; Rita OBEID, Auteur ; Kristen A. BERG, Auteur ; Karen J. ISHLER, Auteur Article en page(s) : 102283 Langues : Anglais (eng) Mots-clés : Family caregivers  Caregiver burden  Worry  Transition to adulthood  Quantitative  Qualitative Index. décimale : PER Périodiques Résumé : Background Caregiver (CG) worry, a dimension of CG burden, has rarely been explored in CGs of transition-aged autistic youth. The present study investigated CG, youth, and service characteristics as potential predictors of CG worry and explored expressed concerns from CGs about their autistic youth and their care. Method Data were drawn from a study of 174 family CGs of transition-age autistic youth (age 16-30 years), living in a midwestern metropolitan area. Using a CG worries scale, CGs rated eight worries (e.g., worry about youth?s safety, etc.) experienced in the past six months. An OLS regression model of CG worry focused on predictors of CG characteristics (age, health, financial burden, involvement in youth?s care), youth characteristics (age, social engagement, adaptive functioning, problematic behavior) and service characteristics (access barriers and engagement in transition planning). CG responses to an open-ended question about their greatest worry regarding the youth and their care were analyzed thematically. Results CGs were mostly middle-aged mothers, caring for predominantly male (71.8%) ASD youth whose average age was 21. Regression models indicated that CG worry was predicted by problematic behaviors and barriers to accessing services. The expressed CG worries were grouped into four themes, including youth reliance on family CGs, possibilities for the youth?s future, youth relationships, and support for youth. Conclusions These findings support the need for improved access to services for transition-aged youth and raise awareness of the need for potential services and interventions to help families manage various worries during this time. En ligne : https://doi.org/10.1016/j.rasd.2023.102283 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=518 [article] "That he won't experience life like he should": Exploring worries of family caregivers of transition-age autistic youth [Texte imprimé et/ou numérique] / Grazia DIPIERRO, Auteur ; Caroline Duke CHAIKIN, Auteur ; Rita OBEID, Auteur ; Kristen A. BERG, Auteur ; Karen J. ISHLER, Auteur . - 102283. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102283 Mots-clés : Family caregivers  Caregiver burden  Worry  Transition to adulthood  Quantitative  Qualitative Index. décimale : PER Périodiques Résumé : Background Caregiver (CG) worry, a dimension of CG burden, has rarely been explored in CGs of transition-aged autistic youth. The present study investigated CG, youth, and service characteristics as potential predictors of CG worry and explored expressed concerns from CGs about their autistic youth and their care. Method Data were drawn from a study of 174 family CGs of transition-age autistic youth (age 16-30 years), living in a midwestern metropolitan area. Using a CG worries scale, CGs rated eight worries (e.g., worry about youth?s safety, etc.) experienced in the past six months. An OLS regression model of CG worry focused on predictors of CG characteristics (age, health, financial burden, involvement in youth?s care), youth characteristics (age, social engagement, adaptive functioning, problematic behavior) and service characteristics (access barriers and engagement in transition planning). CG responses to an open-ended question about their greatest worry regarding the youth and their care were analyzed thematically. Results CGs were mostly middle-aged mothers, caring for predominantly male (71.8%) ASD youth whose average age was 21. Regression models indicated that CG worry was predicted by problematic behaviors and barriers to accessing services. The expressed CG worries were grouped into four themes, including youth reliance on family CGs, possibilities for the youth?s future, youth relationships, and support for youth. Conclusions These findings support the need for improved access to services for transition-aged youth and raise awareness of the need for potential services and interventions to help families manage various worries during this time. En ligne : https://doi.org/10.1016/j.rasd.2023.102283 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=518

Remote vs. in-person schooling during the COVID-19 pandemic and internalizing symptoms among children on the autism spectrum / Chrystyna D. KOUROS ; Naomi V. EKAS ; Sam LEVY in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102284 Titre : Remote vs. in-person schooling during the COVID-19 pandemic and internalizing symptoms among children on the autism spectrum Type de document : Texte imprimé et/ou numérique Auteurs : Chrystyna D. KOUROS, Auteur ; Naomi V. EKAS, Auteur ; Sam LEVY, Auteur Article en page(s) : 102284 Langues : Anglais (eng) Mots-clés : Anxiety  Autism spectrum disorder  Depressive symptoms  COVID-19 pandemic  Remote schooling Index. décimale : PER Périodiques Résumé : Background Children on the autism spectrum encountered interruptions to their education due to the COVID-19 pandemic (White et al., 2021). This study examined the extent to which autistic children?s anxiety and depressive symptoms during the pandemic were associated with the school format they attended in October 2020 (remote, in-person/hybrid, homeschool), controlling for their pre-pandemic symptoms. Pre-pandemic peer victimization and autism symptom characteristics were tested as moderators. Method Participants were 81 verbally-fluent autistic children (Mage = 14.71 years, 77.8 % males), without an intellectual disability, and their mothers; families were part of an ongoing, longitudinal study that began before the pandemic. Results School format did not significantly predict children?s anxiety or depressive symptoms. Results indicated that the only significant predictors of children?s anxiety and depressive symptoms during the pandemic were their pre-pandemic symptom levels. Conclusions School format did not significantly contribute to variability in children?s anxiety and depressive symptoms during the pandemic, over and above their pre-pandemic symptoms. The results contribute quantitative findings to the growing body of research on pandemic-related effects on autistic children, and underscore the need to account for pre-pandemic child functioning when drawing conclusions about pandemic-level effects. En ligne : https://doi.org/10.1016/j.rasd.2023.102284 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=518 [article] Remote vs. in-person schooling during the COVID-19 pandemic and internalizing symptoms among children on the autism spectrum [Texte imprimé et/ou numérique] / Chrystyna D. KOUROS, Auteur ; Naomi V. EKAS, Auteur ; Sam LEVY, Auteur . - 102284. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102284 Mots-clés : Anxiety  Autism spectrum disorder  Depressive symptoms  COVID-19 pandemic  Remote schooling Index. décimale : PER Périodiques Résumé : Background Children on the autism spectrum encountered interruptions to their education due to the COVID-19 pandemic (White et al., 2021). This study examined the extent to which autistic children?s anxiety and depressive symptoms during the pandemic were associated with the school format they attended in October 2020 (remote, in-person/hybrid, homeschool), controlling for their pre-pandemic symptoms. Pre-pandemic peer victimization and autism symptom characteristics were tested as moderators. Method Participants were 81 verbally-fluent autistic children (Mage = 14.71 years, 77.8 % males), without an intellectual disability, and their mothers; families were part of an ongoing, longitudinal study that began before the pandemic. Results School format did not significantly predict children?s anxiety or depressive symptoms. Results indicated that the only significant predictors of children?s anxiety and depressive symptoms during the pandemic were their pre-pandemic symptom levels. Conclusions School format did not significantly contribute to variability in children?s anxiety and depressive symptoms during the pandemic, over and above their pre-pandemic symptoms. The results contribute quantitative findings to the growing body of research on pandemic-related effects on autistic children, and underscore the need to account for pre-pandemic child functioning when drawing conclusions about pandemic-level effects. En ligne : https://doi.org/10.1016/j.rasd.2023.102284 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=518

Omega 3 effects on sleep and body composition in children with autism spectrum disorder: A randomized placebo-controlled trial / Hamideh SALEHI ; Keivan KARIMI ; Kurosh DJAFARIAN in Research in Autism Spectrum Disorders, 109 (November 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 109 (November 2023) . - 102289 Titre : Omega 3 effects on sleep and body composition in children with autism spectrum disorder: A randomized placebo-controlled trial Type de document : Texte imprimé et/ou numérique Auteurs : Hamideh SALEHI, Auteur ; Keivan KARIMI, Auteur ; Kurosh DJAFARIAN, Auteur Article en page(s) : 102289 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Sleep quality  Body composition Index. décimale : PER Périodiques Résumé : Background Sleep disturbances and disruptions in body composition, encompassing factors like fat mass, and lean body mass are common challenges in individuals with autism spectrum disorder (ASD). Despite numerous studies in this field, research has not yet yielded clear and definitive results. Methods In this randomized clinical trial, we investigated the effects of omega-3 supplementation (360 mg DHA and 720 mg EPA) in comparison to placebo (edible paraffin) on sleep-related factors and body composition in a population of 59 boys aged 7-15 (Mean = 9.9, S.D.= 2.1) on autism spectrum disorder for 8 weeks. The diagnoses of ASD were established by an experienced psychiatrist using the criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Results Omega-3 supplementation led to a significant increase in the mean change in sleep duration on 5 non-holiday days by 9.13 min (P = .02; Z = ?2.2) and a corresponding decrease in the mean change in Protein percent of the omega-3 group by 1.7 % (p = .03; T = 2.14) compared with the placebo group after the intervention. However, no significant changes were observed in other factors related to sleep. Furthermore, the intervention group exhibited alterations in macronutrient intake in comparison to the placebo group, showing a 3.4 % increase in carbohydrate percentage (p = .07; [?.37 to 7.27]). Despite these changes, no significant differences in body composition measures were noted between the two groups following the intervention. Conclusion Omega-3 supplementation improves sleep duration in ASD. Future research should consider larger sample sizes and longer intervention periods to further explore the potential benefits of omega-3 supplementation in improving sleep and body composition outcomes in individuals with ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102289 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=518 [article] Omega 3 effects on sleep and body composition in children with autism spectrum disorder: A randomized placebo-controlled trial [Texte imprimé et/ou numérique] / Hamideh SALEHI, Auteur ; Keivan KARIMI, Auteur ; Kurosh DJAFARIAN, Auteur . - 102289. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 109 (November 2023) . - 102289 Mots-clés : Autism spectrum disorder  Sleep quality  Body composition Index. décimale : PER Périodiques Résumé : Background Sleep disturbances and disruptions in body composition, encompassing factors like fat mass, and lean body mass are common challenges in individuals with autism spectrum disorder (ASD). Despite numerous studies in this field, research has not yet yielded clear and definitive results. Methods In this randomized clinical trial, we investigated the effects of omega-3 supplementation (360 mg DHA and 720 mg EPA) in comparison to placebo (edible paraffin) on sleep-related factors and body composition in a population of 59 boys aged 7-15 (Mean = 9.9, S.D.= 2.1) on autism spectrum disorder for 8 weeks. The diagnoses of ASD were established by an experienced psychiatrist using the criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Results Omega-3 supplementation led to a significant increase in the mean change in sleep duration on 5 non-holiday days by 9.13 min (P = .02; Z = ?2.2) and a corresponding decrease in the mean change in Protein percent of the omega-3 group by 1.7 % (p = .03; T = 2.14) compared with the placebo group after the intervention. However, no significant changes were observed in other factors related to sleep. Furthermore, the intervention group exhibited alterations in macronutrient intake in comparison to the placebo group, showing a 3.4 % increase in carbohydrate percentage (p = .07; [?.37 to 7.27]). Despite these changes, no significant differences in body composition measures were noted between the two groups following the intervention. Conclusion Omega-3 supplementation improves sleep duration in ASD. Future research should consider larger sample sizes and longer intervention periods to further explore the potential benefits of omega-3 supplementation in improving sleep and body composition outcomes in individuals with ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102289 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=518