An elevated anxiety level among prepubertal autistic boys with non-treatment-seeking functional gastrointestinal disorders: A case-control study / O. W. H. WONG in Autism Research, 14-10 (October 2021)  

Public ISBD [article]  inAutism Research > 14-10 (October 2021) . - p.2131-2142 Titre : An elevated anxiety level among prepubertal autistic boys with non-treatment-seeking functional gastrointestinal disorders: A case-control study Type de document : Texte imprimé et/ou numérique Auteurs : O. W. H. WONG, Auteur ; A. M. W. LAM, Auteur ; Kelly Y. C. LAI, Auteur ; S. L. MA, Auteur ; S. F. HUNG, Auteur ; S. CHAN, Auteur ; S. WONG, Auteur ; P. W. L. LEUNG, Auteur Article en page(s) : p.2131-2142 Langues : Anglais (eng) Mots-clés : Anxiety/complications  Autism Spectrum Disorder/complications/epidemiology  Autistic Disorder/complications/epidemiology  Case-Control Studies  Child  Child, Preschool  Gastrointestinal Diseases/complications/epidemiology  Humans  Male  abdominal pain  anxiety  autism  constipation  functional gastrointestinal disorder  gut-brain axis  nausea Index. décimale : PER Périodiques Résumé : Children with autism commonly suffer from comorbid functional gastrointestinal disorders (FGID) and anxiety. The raised prevalence of both conditions in autism suggests complex reciprocal relationships, which are seldom explored in non-treatment-seeking FGID. The relationships between subtypes of FGID and anxiety are also unclear. This study recruited boys with autism and age-matched typically developing (TD) boys, aged 4-11?years, who were not actively seeking help for gastrointestinal problems. Their parents completed the Rome IV Diagnostic Questionnaires for Pediatric FGID. Four groups of children with and without autism/FGID were identified and compared on their anxiety level using the Spence children's anxiety scale. In 69 boys with autism and 69 age-matched TD boys, FGID were identified in 22 and 16 boys, respectively. ANCOVA demonstrated a significant interaction effect of autism and FGID on anxiety (F[1, 129] = 5.43, p = 0.021), while conditional logistic regression identified an interaction effect of autism and anxiety on the odds of FGID (OR 1.038, 95% CI 1.002-1.075, p = 0.038). Explorative post hoc analysis showed higher anxiety in functional nausea and vomiting disorder (p = 0.033) and functional abdominal pain disorder (p = 0.029) among boys with autism than TD boys with the same respective subtypes of FGID. In summary, among prepubertal boys with autism, the presence of FGID that are non-treatment-seeking in nature, has a significantly stronger association with higher levels of anxiety than TD boys. The strength of association may be more prominent in subtypes of FGID. Possible pathomechanisms including the underlying microbiota spectra and inflammatory paths should be explored in future studies. LAY SUMMARY: Anxiety and gastrointestinal problems are common symptoms in autism. Given that gut health could be linked to emotions, their association in young boys with autism was studied. The presence of nausea vomiting, or abdominal pain were associated with raised anxiety among boys with autism, yet this was not observed in typically developing boys. This suggests that anxiety among autistic children could be partly explained by the presence of FGID. En ligne : http://dx.doi.org/10.1002/aur.2555 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 [article] An elevated anxiety level among prepubertal autistic boys with non-treatment-seeking functional gastrointestinal disorders: A case-control study [Texte imprimé et/ou numérique] / O. W. H. WONG, Auteur ; A. M. W. LAM, Auteur ; Kelly Y. C. LAI, Auteur ; S. L. MA, Auteur ; S. F. HUNG, Auteur ; S. CHAN, Auteur ; S. WONG, Auteur ; P. W. L. LEUNG, Auteur . - p.2131-2142. Langues : Anglais (eng) in Autism Research > 14-10 (October 2021) . - p.2131-2142 Mots-clés : Anxiety/complications  Autism Spectrum Disorder/complications/epidemiology  Autistic Disorder/complications/epidemiology  Case-Control Studies  Child  Child, Preschool  Gastrointestinal Diseases/complications/epidemiology  Humans  Male  abdominal pain  anxiety  autism  constipation  functional gastrointestinal disorder  gut-brain axis  nausea Index. décimale : PER Périodiques Résumé : Children with autism commonly suffer from comorbid functional gastrointestinal disorders (FGID) and anxiety. The raised prevalence of both conditions in autism suggests complex reciprocal relationships, which are seldom explored in non-treatment-seeking FGID. The relationships between subtypes of FGID and anxiety are also unclear. This study recruited boys with autism and age-matched typically developing (TD) boys, aged 4-11?years, who were not actively seeking help for gastrointestinal problems. Their parents completed the Rome IV Diagnostic Questionnaires for Pediatric FGID. Four groups of children with and without autism/FGID were identified and compared on their anxiety level using the Spence children's anxiety scale. In 69 boys with autism and 69 age-matched TD boys, FGID were identified in 22 and 16 boys, respectively. ANCOVA demonstrated a significant interaction effect of autism and FGID on anxiety (F[1, 129] = 5.43, p = 0.021), while conditional logistic regression identified an interaction effect of autism and anxiety on the odds of FGID (OR 1.038, 95% CI 1.002-1.075, p = 0.038). Explorative post hoc analysis showed higher anxiety in functional nausea and vomiting disorder (p = 0.033) and functional abdominal pain disorder (p = 0.029) among boys with autism than TD boys with the same respective subtypes of FGID. In summary, among prepubertal boys with autism, the presence of FGID that are non-treatment-seeking in nature, has a significantly stronger association with higher levels of anxiety than TD boys. The strength of association may be more prominent in subtypes of FGID. Possible pathomechanisms including the underlying microbiota spectra and inflammatory paths should be explored in future studies. LAY SUMMARY: Anxiety and gastrointestinal problems are common symptoms in autism. Given that gut health could be linked to emotions, their association in young boys with autism was studied. The presence of nausea vomiting, or abdominal pain were associated with raised anxiety among boys with autism, yet this was not observed in typically developing boys. This suggests that anxiety among autistic children could be partly explained by the presence of FGID. En ligne : http://dx.doi.org/10.1002/aur.2555 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450

Autism Diagnostic Interview-Revised Within DSM-5 Framework: Test of Reliability and Validity in Chinese Children / Kelly Y. C. LAI in Journal of Autism and Developmental Disorders, 52-4 (April 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-4 (April 2022) . - p.1807-1820 Titre : Autism Diagnostic Interview-Revised Within DSM-5 Framework: Test of Reliability and Validity in Chinese Children Type de document : Texte imprimé et/ou numérique Auteurs : Kelly Y. C. LAI, Auteur ; Emily C. W. YUEN, Auteur ; Se Fong HUNG, Auteur ; Patrick W. L. LEUNG, Auteur Article en page(s) : p.1807-1820 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis  Autistic Disorder/diagnosis  Child  China  Diagnostic and Statistical Manual of Mental Disorders  Humans  Reproducibility of Results  Adhd  Adi-r  Chinese  Dsm-5  Validity Index. décimale : PER Périodiques Résumé : This study examines the psychometric properties of the Autism Diagnostic Interview-Revised (ADI-R) in the context of DSM-5 in a sample of Chinese children. Using re-mapped ADI-R items and algorithms matched to DSM-5 criteria, and administering to children with autism spectrum disorder (ASD) with and without intellectual disability, attention-deficit hyperactivity disorder, and typically developing, it evidenced high sensitivity and specificity. However, similar to DSM-IV algorithm, the DSM-5 algorithms were better at classifying ASD among children with intellectual disability than among those without intellectual disability. With the DSM-5's recognition of the spectrum nature of ASD, the performance of the ADI-R can be improved by having finer gradations in the ADI-R scoring and adding more items on the restricted and repetitve behavior domain. En ligne : http://dx.doi.org/10.1007/s10803-021-05079-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=476 [article] Autism Diagnostic Interview-Revised Within DSM-5 Framework: Test of Reliability and Validity in Chinese Children [Texte imprimé et/ou numérique] / Kelly Y. C. LAI, Auteur ; Emily C. W. YUEN, Auteur ; Se Fong HUNG, Auteur ; Patrick W. L. LEUNG, Auteur . - p.1807-1820. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-4 (April 2022) . - p.1807-1820 Mots-clés : Autism Spectrum Disorder/diagnosis  Autistic Disorder/diagnosis  Child  China  Diagnostic and Statistical Manual of Mental Disorders  Humans  Reproducibility of Results  Adhd  Adi-r  Chinese  Dsm-5  Validity Index. décimale : PER Périodiques Résumé : This study examines the psychometric properties of the Autism Diagnostic Interview-Revised (ADI-R) in the context of DSM-5 in a sample of Chinese children. Using re-mapped ADI-R items and algorithms matched to DSM-5 criteria, and administering to children with autism spectrum disorder (ASD) with and without intellectual disability, attention-deficit hyperactivity disorder, and typically developing, it evidenced high sensitivity and specificity. However, similar to DSM-IV algorithm, the DSM-5 algorithms were better at classifying ASD among children with intellectual disability than among those without intellectual disability. With the DSM-5's recognition of the spectrum nature of ASD, the performance of the ADI-R can be improved by having finer gradations in the ADI-R scoring and adding more items on the restricted and repetitve behavior domain. En ligne : http://dx.doi.org/10.1007/s10803-021-05079-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=476

Brief Report: Mindfulness Training for Chinese Adolescents with Autism Spectrum Disorder and Their Parents in Hong Kong / R. Y. F. HO in Journal of Autism and Developmental Disorders, 51-11 (November 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-11 (November 2021) . - p.4147-4159 Titre : Brief Report: Mindfulness Training for Chinese Adolescents with Autism Spectrum Disorder and Their Parents in Hong Kong Type de document : Texte imprimé et/ou numérique Auteurs : R. Y. F. HO, Auteur ; D. ZHANG, Auteur ; S. K. C. CHAN, Auteur ; T. T. GAO, Auteur ; E. K. P. LEE, Auteur ; H. H. M. LO, Auteur ; P. AU YEUNG, Auteur ; Kelly Y. C. LAI, Auteur ; Susan M. BOGELS, Auteur ; E. I. DE BRUIN, Auteur ; S. Y. S. WONG, Auteur Article en page(s) : p.4147-4159 Langues : Anglais (eng) Mots-clés : Adolescent  Autism Spectrum Disorder/therapy  China  Hong Kong  Humans  Mindfulness  Parenting  Parents  Autism spectrum disorder  Effectiveness  Feasibility  MYmind Index. décimale : PER Périodiques Résumé : This study investigated the feasibility and preliminary effectiveness of a concurrent mindfulness program (MYmind) on Chinese adolescents with autism spectrum disorder and their parents in Hong Kong, China using a randomized controlled trial with a waitlist control group. Results showed the study had 80% compliance rate, 0% dropout rate, and 89% response rate. Between-group comparisons showed mindfulness had trend effects on parent's rumination (g?=?1.16), mindful parenting (d?=?0.6), parenting style (d?=?0.59), and parenting stress (d?=?0.5). The study demonstrated the feasibility of the MYmind program in the Chinese context. A larger trial with longer follow-up period is suggested to better examine the effect of mindfulness on adolescents with ASD and their parents. En ligne : http://dx.doi.org/10.1007/s10803-020-04729-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454 [article] Brief Report: Mindfulness Training for Chinese Adolescents with Autism Spectrum Disorder and Their Parents in Hong Kong [Texte imprimé et/ou numérique] / R. Y. F. HO, Auteur ; D. ZHANG, Auteur ; S. K. C. CHAN, Auteur ; T. T. GAO, Auteur ; E. K. P. LEE, Auteur ; H. H. M. LO, Auteur ; P. AU YEUNG, Auteur ; Kelly Y. C. LAI, Auteur ; Susan M. BOGELS, Auteur ; E. I. DE BRUIN, Auteur ; S. Y. S. WONG, Auteur . - p.4147-4159. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-11 (November 2021) . - p.4147-4159 Mots-clés : Adolescent  Autism Spectrum Disorder/therapy  China  Hong Kong  Humans  Mindfulness  Parenting  Parents  Autism spectrum disorder  Effectiveness  Feasibility  MYmind Index. décimale : PER Périodiques Résumé : This study investigated the feasibility and preliminary effectiveness of a concurrent mindfulness program (MYmind) on Chinese adolescents with autism spectrum disorder and their parents in Hong Kong, China using a randomized controlled trial with a waitlist control group. Results showed the study had 80% compliance rate, 0% dropout rate, and 89% response rate. Between-group comparisons showed mindfulness had trend effects on parent's rumination (g?=?1.16), mindful parenting (d?=?0.6), parenting style (d?=?0.59), and parenting stress (d?=?0.5). The study demonstrated the feasibility of the MYmind program in the Chinese context. A larger trial with longer follow-up period is suggested to better examine the effect of mindfulness on adolescents with ASD and their parents. En ligne : http://dx.doi.org/10.1007/s10803-020-04729-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454

Executive function in children and adolescents with posttraumatic stress disorder 4 and 12 months after the Sichuan earthquake in China / Rui YANG in Journal of Child Psychology and Psychiatry, 55-1 (January 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-1 (January 2014) . - p.31-38 Titre : Executive function in children and adolescents with posttraumatic stress disorder 4 and 12 months after the Sichuan earthquake in China Type de document : Texte imprimé et/ou numérique Auteurs : Rui YANG, Auteur ; Yu-Tao XIANG, Auteur ; Lan SHUAI, Auteur ; Ying QIAN, Auteur ; Kelly Y. C. LAI, Auteur ; Gabor S. UNGVARI, Auteur ; Helen F. K. CHIU, Auteur ; Yu-Feng WANG, Auteur Article en page(s) : p.31-38 Langues : Anglais (eng) Mots-clés : Posttraumatic stress disorder  children and adolescents  executive function  earthquake Index. décimale : PER Périodiques Résumé : Background While several studies have found executive function deficits in adults and maltreated children with posttraumatic stress disorder (PTSD), there are few data on executive function in children and adolescents with PTSD related to natural disasters. The objective of this study was to test executive function changes over time in children and adolescents with PTSD after a magnitude 8.0 earthquake in Sichuan, China. Method A sample of 34 children and adolescents with diagnosed PTSD following the Sichuan earthquake and 66 matched controls exposed to the same earthquake but without PTSD participated in the study. Executive function was assessed using a battery of interviewer-rated neuropsychological tests and the guardian-rated Behavior Rating Scale of Executive Function (BRIEF) at 4- and 12-month after the earthquake. Results Children and adolescents with PTSD performed similar to controls in executive function at 4-months after the earthquake. Both groups improved significantly in similar domains of cognition during the following 8 months. The PTSD group exhibited daily deficits in emotional control compared with the controls at the 4-month assessment, but the differences disappeared during the following 8 months. Conclusions Children and adolescents with PTSD related to a natural disaster have deficits only in the emotional control domain of executive function compared with controls exposed to the same disaster, but even these deficits did not persist. En ligne : http://dx.doi.org/10.1111/jcpp.12089 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=220 [article] Executive function in children and adolescents with posttraumatic stress disorder 4 and 12 months after the Sichuan earthquake in China [Texte imprimé et/ou numérique] / Rui YANG, Auteur ; Yu-Tao XIANG, Auteur ; Lan SHUAI, Auteur ; Ying QIAN, Auteur ; Kelly Y. C. LAI, Auteur ; Gabor S. UNGVARI, Auteur ; Helen F. K. CHIU, Auteur ; Yu-Feng WANG, Auteur . - p.31-38. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-1 (January 2014) . - p.31-38 Mots-clés : Posttraumatic stress disorder  children and adolescents  executive function  earthquake Index. décimale : PER Périodiques Résumé : Background While several studies have found executive function deficits in adults and maltreated children with posttraumatic stress disorder (PTSD), there are few data on executive function in children and adolescents with PTSD related to natural disasters. The objective of this study was to test executive function changes over time in children and adolescents with PTSD after a magnitude 8.0 earthquake in Sichuan, China. Method A sample of 34 children and adolescents with diagnosed PTSD following the Sichuan earthquake and 66 matched controls exposed to the same earthquake but without PTSD participated in the study. Executive function was assessed using a battery of interviewer-rated neuropsychological tests and the guardian-rated Behavior Rating Scale of Executive Function (BRIEF) at 4- and 12-month after the earthquake. Results Children and adolescents with PTSD performed similar to controls in executive function at 4-months after the earthquake. Both groups improved significantly in similar domains of cognition during the following 8 months. The PTSD group exhibited daily deficits in emotional control compared with the controls at the 4-month assessment, but the differences disappeared during the following 8 months. Conclusions Children and adolescents with PTSD related to a natural disaster have deficits only in the emotional control domain of executive function compared with controls exposed to the same disaster, but even these deficits did not persist. En ligne : http://dx.doi.org/10.1111/jcpp.12089 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=220

Validation of the Developmental, Dimensional and Diagnostic Interview (3Di) Among Chinese Children in a Child Psychiatry Clinic in Hong Kong / Kelly Y. C. LAI in Journal of Autism and Developmental Disorders, 45-5 (May 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-5 (May 2015) . - p.1230-1237 Titre : Validation of the Developmental, Dimensional and Diagnostic Interview (3Di) Among Chinese Children in a Child Psychiatry Clinic in Hong Kong Type de document : Texte imprimé et/ou numérique Auteurs : Kelly Y. C. LAI, Auteur ; Patrick W. L. LEUNG, Auteur ; Flora Y. M. MO, Auteur ; Marshall M. C. LEE, Auteur ; Caroline K. S. SHEA, Auteur ; Grace F. C. CHAN, Auteur ; Kiti K. I. CHE, Auteur ; Ernest S. L. LUK, Auteur ; Arthur D. P. MAK, Auteur ; Richard WARRINGTON, Auteur ; David SKUSE, Auteur Article en page(s) : p.1230-1237 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  3Di  Chinese  Validation Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is a disorder with high levels of co-morbidities. The Developmental, Dimensional and Diagnostic Interview (3Di) is a relatively new instrument designed to provide dimensional as well as categorical assessment of autistic behaviours among children with normal intelligence. Its sound psychometric properties and relatively short administration time make it a versatile instrument. The 3Di was translated into Chinese (Cantonese) and its applicability among 194 clinic children was examined. Results found excellent reliability and validity, and achieved a sensitivity of 95 % and specificity of 77 %. It was able to capture the diagnosis of ASD among children presenting with attention deficit hyperactivity disorder. However, although the disorder of ASD is considered universal, the use of a western instrument in a Chinese context should also take note of cultural influences that may impact on the manifestation of its symptoms. En ligne : http://dx.doi.org/10.1007/s10803-014-2284-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259 [article] Validation of the Developmental, Dimensional and Diagnostic Interview (3Di) Among Chinese Children in a Child Psychiatry Clinic in Hong Kong [Texte imprimé et/ou numérique] / Kelly Y. C. LAI, Auteur ; Patrick W. L. LEUNG, Auteur ; Flora Y. M. MO, Auteur ; Marshall M. C. LEE, Auteur ; Caroline K. S. SHEA, Auteur ; Grace F. C. CHAN, Auteur ; Kiti K. I. CHE, Auteur ; Ernest S. L. LUK, Auteur ; Arthur D. P. MAK, Auteur ; Richard WARRINGTON, Auteur ; David SKUSE, Auteur . - p.1230-1237. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-5 (May 2015) . - p.1230-1237 Mots-clés : Autism spectrum disorder  3Di  Chinese  Validation Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is a disorder with high levels of co-morbidities. The Developmental, Dimensional and Diagnostic Interview (3Di) is a relatively new instrument designed to provide dimensional as well as categorical assessment of autistic behaviours among children with normal intelligence. Its sound psychometric properties and relatively short administration time make it a versatile instrument. The 3Di was translated into Chinese (Cantonese) and its applicability among 194 clinic children was examined. Results found excellent reliability and validity, and achieved a sensitivity of 95 % and specificity of 77 %. It was able to capture the diagnosis of ASD among children presenting with attention deficit hyperactivity disorder. However, although the disorder of ASD is considered universal, the use of a western instrument in a Chinese context should also take note of cultural influences that may impact on the manifestation of its symptoms. En ligne : http://dx.doi.org/10.1007/s10803-014-2284-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259

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