Dépouillements

A brief telehealth parent training for children with autism spectrum disorder and sleep disturbances: A pilot study / Imanol SETIEN-RAMOS ; Teresa ALONZO-CASTILLO ; Aina GARCÍA-MARTÍNEZ ; María José JURADO-LUQUE ; Odile Romero SANTO-TOMÁS ; María MARTÍNEZ-RAMÍREZ ; Josep Antoni RAMOS-QUIROGA ; Laura GISBERT-GUSTEMPS in Research in Autism, 125 (July 2025)  

Public ISBD [article]  inResearch in Autism > 125 (July 2025) . - p.202601 Titre : A brief telehealth parent training for children with autism spectrum disorder and sleep disturbances: A pilot study Type de document : Texte imprimé et/ou numérique Auteurs : Imanol SETIEN-RAMOS, Auteur ; Teresa ALONZO-CASTILLO, Auteur ; Aina GARCÍA-MARTÍNEZ, Auteur ; María José JURADO-LUQUE, Auteur ; Odile Romero SANTO-TOMÁS, Auteur ; María MARTÍNEZ-RAMÍREZ, Auteur ; Josep Antoni RAMOS-QUIROGA, Auteur ; Laura GISBERT-GUSTEMPS, Auteur Article en page(s) : p.202601 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Sleep  Pre-school children  School-age children  Interventions - psychosocial/behavioral  Telehealth Index. décimale : PER Périodiques Résumé : Background Parent-mediated telehealth interventions have demonstrated effectiveness in managing sleep disturbances in children with Autism Spectrum Disorder (ASD). Objectives This study aims to evaluate the preliminary feasibility, acceptability, and efficacy of a brief telehealth parent training program designed for children with ASD experiencing sleep disturbances. Methods This open-label trial involved 50 children aged 3 to 12 years with ASD and sleep issues. Participants underwent a four-session group telehealth parent training program targeting sleep disturbances, chronotype regulation, behavioral difficulties, and parent quality of life. A follow-up phone session was conducted one month after the intervention. Results Post-intervention analysis revealed a significant improvement in the parent-reported sleep questionnaire for children with ASD (Cohen's d = 0.64). Sleep logs indicated a statistically significant enhancement in sleep efficiency (Cohen's d = ?0.52). The parent-reported chronotype questionnaire showed significant changes at the one-month follow-up (Cohen's d = 0.48). No significant differences were observed regarding behavioral difficulties. Improvements in parent-reported health-related quality of life were noted (Cohen's d = ?0.79 post-intervention; Cohen's d = ?1.15 at one-month follow-up). Treatment fidelity was high, and participant satisfaction was elevated, reflecting perceived effectiveness and favorable cost-benefit ratio. Conclusions The brief telehealth parent training intervention demonstrates potential in improving sleep issues and regulating chronotype in children with ASD, with promising results in terms of feasibility, acceptability, and preliminary efficacy. En ligne : https://doi.org/10.1016/j.reia.2025.202601 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] A brief telehealth parent training for children with autism spectrum disorder and sleep disturbances: A pilot study [Texte imprimé et/ou numérique] / Imanol SETIEN-RAMOS, Auteur ; Teresa ALONZO-CASTILLO, Auteur ; Aina GARCÍA-MARTÍNEZ, Auteur ; María José JURADO-LUQUE, Auteur ; Odile Romero SANTO-TOMÁS, Auteur ; María MARTÍNEZ-RAMÍREZ, Auteur ; Josep Antoni RAMOS-QUIROGA, Auteur ; Laura GISBERT-GUSTEMPS, Auteur . - p.202601. Langues : Anglais (eng) in Research in Autism > 125 (July 2025) . - p.202601 Mots-clés : Autism spectrum disorder  Sleep  Pre-school children  School-age children  Interventions - psychosocial/behavioral  Telehealth Index. décimale : PER Périodiques Résumé : Background Parent-mediated telehealth interventions have demonstrated effectiveness in managing sleep disturbances in children with Autism Spectrum Disorder (ASD). Objectives This study aims to evaluate the preliminary feasibility, acceptability, and efficacy of a brief telehealth parent training program designed for children with ASD experiencing sleep disturbances. Methods This open-label trial involved 50 children aged 3 to 12 years with ASD and sleep issues. Participants underwent a four-session group telehealth parent training program targeting sleep disturbances, chronotype regulation, behavioral difficulties, and parent quality of life. A follow-up phone session was conducted one month after the intervention. Results Post-intervention analysis revealed a significant improvement in the parent-reported sleep questionnaire for children with ASD (Cohen's d = 0.64). Sleep logs indicated a statistically significant enhancement in sleep efficiency (Cohen's d = ?0.52). The parent-reported chronotype questionnaire showed significant changes at the one-month follow-up (Cohen's d = 0.48). No significant differences were observed regarding behavioral difficulties. Improvements in parent-reported health-related quality of life were noted (Cohen's d = ?0.79 post-intervention; Cohen's d = ?1.15 at one-month follow-up). Treatment fidelity was high, and participant satisfaction was elevated, reflecting perceived effectiveness and favorable cost-benefit ratio. Conclusions The brief telehealth parent training intervention demonstrates potential in improving sleep issues and regulating chronotype in children with ASD, with promising results in terms of feasibility, acceptability, and preliminary efficacy. En ligne : https://doi.org/10.1016/j.reia.2025.202601 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559

Dual-task interference pattern in autistic children: A case-control study / Rihab BORJI ; Mohamed Achraf HARRABI ; Malek BELAIBA ; Haithem REBAI ; Sonia SAHLI in Research in Autism, 125 (July 2025)  

Public ISBD [article]  inResearch in Autism > 125 (July 2025) . - p.202602 Titre : Dual-task interference pattern in autistic children: A case-control study Type de document : Texte imprimé et/ou numérique Auteurs : Rihab BORJI, Auteur ; Mohamed Achraf HARRABI, Auteur ; Malek BELAIBA, Auteur ; Haithem REBAI, Auteur ; Sonia SAHLI, Auteur Article en page(s) : p.202602 Langues : Anglais (eng) Mots-clés : Dual task interference  Children  Autism spectrum disorders Index. décimale : PER Périodiques Résumé : This study aimed to investigate the dual task (DT) effects on postural balance during various cognitive and postural tasks in children with autism spectrum disorders (ASD) aged 6-9 years. Eleven children with ASD and eleven with neurotypical development (NTD) participated in this study. Postural and cognitive performances for the word memorization (WM) and the semantic verbal fluency (SVF) tests were recorded during single task (ST) and DT conditions. Postural balance was evaluated in three postural conditions: Firm eyes open (Firm-EO), Firm eyes closed (Firm-EC) and Foam-EO. Motor and cognitive DT costs (DTC) were analyzed across these different cognitive and postural conditions. Results showed that, in both ASD and NTD children postural performance was significantly altered during all DT conditions, compared to the ST situation. In ASD children, the motor DTC was significantly (p < 0.001) higher while performing the SVF task than the WM in all postural conditions. Nevertheless, in the NTD group, the motor DTC was significantly (p < 0.001) higher in the SVF cognitive task only for the Foam-EO condition. When performing the WM task, the ASD group presented significantly greater DTC compared to the NTD group in the Foam-EO (p = 0.004) condition whereas there was no difference (p = 1) in the Firm-EO or the Firm-EC conditions. However, regarding the SVF task, the ASD group had higher motor DTC in all postural conditions (p < 0.001 for the Firm-EO and the Foam-EO and p = 0.008 for the Firm-EC). In conclusion, both ASD and NTD children aged 6-9 years present a mutual interference when performing concurrently postural and cognitive tasks. Based on DTCs findings, these DT effects were more pronounced in children with ASD compared to controls; and were modulated according to the postural and cognitive tasks load. En ligne : https://doi.org/10.1016/j.reia.2025.202602 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] Dual-task interference pattern in autistic children: A case-control study [Texte imprimé et/ou numérique] / Rihab BORJI, Auteur ; Mohamed Achraf HARRABI, Auteur ; Malek BELAIBA, Auteur ; Haithem REBAI, Auteur ; Sonia SAHLI, Auteur . - p.202602. Langues : Anglais (eng) in Research in Autism > 125 (July 2025) . - p.202602 Mots-clés : Dual task interference  Children  Autism spectrum disorders Index. décimale : PER Périodiques Résumé : This study aimed to investigate the dual task (DT) effects on postural balance during various cognitive and postural tasks in children with autism spectrum disorders (ASD) aged 6-9 years. Eleven children with ASD and eleven with neurotypical development (NTD) participated in this study. Postural and cognitive performances for the word memorization (WM) and the semantic verbal fluency (SVF) tests were recorded during single task (ST) and DT conditions. Postural balance was evaluated in three postural conditions: Firm eyes open (Firm-EO), Firm eyes closed (Firm-EC) and Foam-EO. Motor and cognitive DT costs (DTC) were analyzed across these different cognitive and postural conditions. Results showed that, in both ASD and NTD children postural performance was significantly altered during all DT conditions, compared to the ST situation. In ASD children, the motor DTC was significantly (p < 0.001) higher while performing the SVF task than the WM in all postural conditions. Nevertheless, in the NTD group, the motor DTC was significantly (p < 0.001) higher in the SVF cognitive task only for the Foam-EO condition. When performing the WM task, the ASD group presented significantly greater DTC compared to the NTD group in the Foam-EO (p = 0.004) condition whereas there was no difference (p = 1) in the Firm-EO or the Firm-EC conditions. However, regarding the SVF task, the ASD group had higher motor DTC in all postural conditions (p < 0.001 for the Firm-EO and the Foam-EO and p = 0.008 for the Firm-EC). In conclusion, both ASD and NTD children aged 6-9 years present a mutual interference when performing concurrently postural and cognitive tasks. Based on DTCs findings, these DT effects were more pronounced in children with ASD compared to controls; and were modulated according to the postural and cognitive tasks load. En ligne : https://doi.org/10.1016/j.reia.2025.202602 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559

Controlled randomized crossover of essential oils for quality of life in children with autism spectrum disorder (ASD): A pilot and feasibility study / Xueliang PAN ; Taylor WONG ; Craig WILLIAMS ; Cheryl JAMES ; L. Eugene ARNOLD in Research in Autism, 125 (July 2025)  

Public ISBD [article]  inResearch in Autism > 125 (July 2025) . - p.202603 Titre : Controlled randomized crossover of essential oils for quality of life in children with autism spectrum disorder (ASD): A pilot and feasibility study Type de document : Texte imprimé et/ou numérique Auteurs : Xueliang PAN, Auteur ; Taylor WONG, Auteur ; Craig WILLIAMS, Auteur ; Cheryl JAMES, Auteur ; L. Eugene ARNOLD, Auteur Article en page(s) : p.202603 Langues : Anglais (eng) Mots-clés : Essential oils  Autism spectrum disorder  Feasibility study  Quality of life  Sleep  Anxiety  Proinflammatory cytokines Index. décimale : PER Périodiques Résumé : Introduction Essential oils have been touted to benefit children with autism spectrum disorder (ASD) in a multitude of ways. However, the lack of empirical evidence makes it difficult to accept this claim. We tested the feasibility of conducting a large randomized clinical crossover trial of an essential oils blend in children with ASD and evaluated its safety and efficacy for improving quality of life. Methods Children ages 3-9 with ASD were randomized to a crossover study of Reconnect?, an essential oils blend, versus a control. Outcomes were the Pediatric Quality of Life Inventory, Parent-Rated Anxiety Scale for ASD, Children?s Sleep Habits Questionnaire, and laboratory safety tests. Inflammatory cytokines and other labs were explored. Mixed-effects analyses were applied. Results Twenty-six participants evaluated as intent-to-treat population. Seventeen completed both conditions (61 %). Outcomes improved, but between-treatment differences in the crossover were nonsignificant (p = .33-.16). At first treatment endpoint, anxiety decreased significantly more with active than control (p = .015, d=1.01). Adverse events and hematological/hepatic/renal tests revealed no significant differences. C-reactive protein and interleukin-6 (IL-6) revealed no inflammation. Conclusion Recruitment was feasible, adherence was high, first-condition retention was high (92.7 %). Retention in second condition was low (65.4 %). A large crossover is not feasible. Anxiety results suggest further study in a randomized controlled trial with a parallel-groups design. Reconnect? appears safe. En ligne : https://doi.org/10.1016/j.reia.2025.202603 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] Controlled randomized crossover of essential oils for quality of life in children with autism spectrum disorder (ASD): A pilot and feasibility study [Texte imprimé et/ou numérique] / Xueliang PAN, Auteur ; Taylor WONG, Auteur ; Craig WILLIAMS, Auteur ; Cheryl JAMES, Auteur ; L. Eugene ARNOLD, Auteur . - p.202603. Langues : Anglais (eng) in Research in Autism > 125 (July 2025) . - p.202603 Mots-clés : Essential oils  Autism spectrum disorder  Feasibility study  Quality of life  Sleep  Anxiety  Proinflammatory cytokines Index. décimale : PER Périodiques Résumé : Introduction Essential oils have been touted to benefit children with autism spectrum disorder (ASD) in a multitude of ways. However, the lack of empirical evidence makes it difficult to accept this claim. We tested the feasibility of conducting a large randomized clinical crossover trial of an essential oils blend in children with ASD and evaluated its safety and efficacy for improving quality of life. Methods Children ages 3-9 with ASD were randomized to a crossover study of Reconnect?, an essential oils blend, versus a control. Outcomes were the Pediatric Quality of Life Inventory, Parent-Rated Anxiety Scale for ASD, Children?s Sleep Habits Questionnaire, and laboratory safety tests. Inflammatory cytokines and other labs were explored. Mixed-effects analyses were applied. Results Twenty-six participants evaluated as intent-to-treat population. Seventeen completed both conditions (61 %). Outcomes improved, but between-treatment differences in the crossover were nonsignificant (p = .33-.16). At first treatment endpoint, anxiety decreased significantly more with active than control (p = .015, d=1.01). Adverse events and hematological/hepatic/renal tests revealed no significant differences. C-reactive protein and interleukin-6 (IL-6) revealed no inflammation. Conclusion Recruitment was feasible, adherence was high, first-condition retention was high (92.7 %). Retention in second condition was low (65.4 %). A large crossover is not feasible. Anxiety results suggest further study in a randomized controlled trial with a parallel-groups design. Reconnect? appears safe. En ligne : https://doi.org/10.1016/j.reia.2025.202603 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559

Assessment of cardiac outcomes of children and adolescents with autism spectrum disorder and developmental coordination disorder: A systematic review / Ricele da Silva BRITO ; Lucinete Sena de Oliveira SILVA ; Antonio Roberto ZAMUNÉR in Research in Autism, 125 (July 2025)  

Public ISBD [article]  inResearch in Autism > 125 (July 2025) . - p.202604 Titre : Assessment of cardiac outcomes of children and adolescents with autism spectrum disorder and developmental coordination disorder: A systematic review Type de document : Texte imprimé et/ou numérique Auteurs : Ricele da Silva BRITO, Auteur ; Lucinete Sena de Oliveira SILVA, Auteur ; Antonio Roberto ZAMUNÉR, Auteur Article en page(s) : p.202604 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Developmental coordination disorder  Heart rate variability  Cardiac autonomic control Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder (ASD) and Developmental coordination disorder (DCD) are neurodevelopmental disorders that have a worldwide prevalence between 1 % and 5 % in school-aged children. In addition to the primary symptoms of each disorder, cardiac alterations appear to be superior to those seen in typically developing children. Therefore, the aim of this study was to summarize evidence regarding cardiac outcomes of children and adolescents with ASD and DCD compared to typically developing controls. Method This is a systematic review study, registered with PROSPERO, number CRD42021268196. Studies were searched on PubMed, Scopus, PEDro database, Web of Science, and PsycohINFO. We included original case-control and cross-sectional articles conducted with children aged between 6-12 years and/or adolescents between 13-18 years with a diagnosis of ASD and/or DCD, evaluating cardiac outcomes, such as Heart Rate Variability (HRV) and Heart Rate (HR). The risk of bias was evaluated through the Newcastle - Ottawa Scale (NOS). Results Out of the 2118 studies retrieved in the initial databases searches, ten were included in this systematic review and classified as having moderate to high methodological quality. Children and adolescents with ASD and DCD showed significantly alterations on their cardiac outcomes, particularly in the modulation of the cardiac autonomic control, assessed through HRV compared to those typically developing. Conclusion This systematic review uncovered that children/adolescents with ASD and DCD have cardiac alterations, characterized by higher sympathetic and lower parasympathetic modulation during resting and in response to distress. HRV assessment in this population is important for early detection of cardiac dysfunctions. More studies are recommended to expansion of the literature in this field. En ligne : https://doi.org/10.1016/j.reia.2025.202604 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] Assessment of cardiac outcomes of children and adolescents with autism spectrum disorder and developmental coordination disorder: A systematic review [Texte imprimé et/ou numérique] / Ricele da Silva BRITO, Auteur ; Lucinete Sena de Oliveira SILVA, Auteur ; Antonio Roberto ZAMUNÉR, Auteur . - p.202604. Langues : Anglais (eng) in Research in Autism > 125 (July 2025) . - p.202604 Mots-clés : Autism spectrum disorder  Developmental coordination disorder  Heart rate variability  Cardiac autonomic control Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder (ASD) and Developmental coordination disorder (DCD) are neurodevelopmental disorders that have a worldwide prevalence between 1 % and 5 % in school-aged children. In addition to the primary symptoms of each disorder, cardiac alterations appear to be superior to those seen in typically developing children. Therefore, the aim of this study was to summarize evidence regarding cardiac outcomes of children and adolescents with ASD and DCD compared to typically developing controls. Method This is a systematic review study, registered with PROSPERO, number CRD42021268196. Studies were searched on PubMed, Scopus, PEDro database, Web of Science, and PsycohINFO. We included original case-control and cross-sectional articles conducted with children aged between 6-12 years and/or adolescents between 13-18 years with a diagnosis of ASD and/or DCD, evaluating cardiac outcomes, such as Heart Rate Variability (HRV) and Heart Rate (HR). The risk of bias was evaluated through the Newcastle - Ottawa Scale (NOS). Results Out of the 2118 studies retrieved in the initial databases searches, ten were included in this systematic review and classified as having moderate to high methodological quality. Children and adolescents with ASD and DCD showed significantly alterations on their cardiac outcomes, particularly in the modulation of the cardiac autonomic control, assessed through HRV compared to those typically developing. Conclusion This systematic review uncovered that children/adolescents with ASD and DCD have cardiac alterations, characterized by higher sympathetic and lower parasympathetic modulation during resting and in response to distress. HRV assessment in this population is important for early detection of cardiac dysfunctions. More studies are recommended to expansion of the literature in this field. En ligne : https://doi.org/10.1016/j.reia.2025.202604 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559

Connection between autistic traits, self-esteem, and interpersonal trust: A distinct separation of implicit and explicit components / Zhen CAO ; Xuehua XU ; Xintong LI ; Aijia XU ; Wendian SHI in Research in Autism, 125 (July 2025)  

Public ISBD [article]  inResearch in Autism > 125 (July 2025) . - p.202605 Titre : Connection between autistic traits, self-esteem, and interpersonal trust: A distinct separation of implicit and explicit components Type de document : Texte imprimé et/ou numérique Auteurs : Zhen CAO, Auteur ; Xuehua XU, Auteur ; Xintong LI, Auteur ; Aijia XU, Auteur ; Wendian SHI, Auteur Article en page(s) : p.202605 Langues : Anglais (eng) Mots-clés : Autistic traits  Autism spectrum condition  Self-esteem  Dual-processing mode  Trust Index. décimale : PER Périodiques Résumé : Interpersonal trust is the foundation for initiating and maintaining social interactions. Knowing the association between autistic traits (ATs) and trust, along with the mediating mechanisms, aids in better understanding the social interaction profile related to the autism spectrum. Using the dual-processing model of social cognition, the present study investigates the links between ATs and explicit and implicit trust, as well as the potential mediating role of explicit and implicit self-esteem in these relationships. In total, 291 neurotypical participants completed questionnaires assessing ATs, explicit self-esteem, and explicit trust. They also underwent the Implicit Association Test evaluating implicit self-esteem and implicit trust. The correlation test, independent sample t-tests, and mediation analyses were also conducted. ATs exhibited a significant negative correlation with explicit trust and explicit self-esteem but no significant relationship with implicit trust and implicit self-esteem. Explicit self-esteem mediated the relationship between ATs and explicit trust. The findings suggest that, on the explicit pathway, ATs influence trust through self-esteem mechanisms. Importantly, the study revealed a clear distinction between implicit and explicit pathways in the relationship between ATs, trust, and self-esteem, offering valuable insights into the AT-associated social cognitive characteristics. En ligne : https://doi.org/10.1016/j.reia.2025.202605 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] Connection between autistic traits, self-esteem, and interpersonal trust: A distinct separation of implicit and explicit components [Texte imprimé et/ou numérique] / Zhen CAO, Auteur ; Xuehua XU, Auteur ; Xintong LI, Auteur ; Aijia XU, Auteur ; Wendian SHI, Auteur . - p.202605. Langues : Anglais (eng) in Research in Autism > 125 (July 2025) . - p.202605 Mots-clés : Autistic traits  Autism spectrum condition  Self-esteem  Dual-processing mode  Trust Index. décimale : PER Périodiques Résumé : Interpersonal trust is the foundation for initiating and maintaining social interactions. Knowing the association between autistic traits (ATs) and trust, along with the mediating mechanisms, aids in better understanding the social interaction profile related to the autism spectrum. Using the dual-processing model of social cognition, the present study investigates the links between ATs and explicit and implicit trust, as well as the potential mediating role of explicit and implicit self-esteem in these relationships. In total, 291 neurotypical participants completed questionnaires assessing ATs, explicit self-esteem, and explicit trust. They also underwent the Implicit Association Test evaluating implicit self-esteem and implicit trust. The correlation test, independent sample t-tests, and mediation analyses were also conducted. ATs exhibited a significant negative correlation with explicit trust and explicit self-esteem but no significant relationship with implicit trust and implicit self-esteem. Explicit self-esteem mediated the relationship between ATs and explicit trust. The findings suggest that, on the explicit pathway, ATs influence trust through self-esteem mechanisms. Importantly, the study revealed a clear distinction between implicit and explicit pathways in the relationship between ATs, trust, and self-esteem, offering valuable insights into the AT-associated social cognitive characteristics. En ligne : https://doi.org/10.1016/j.reia.2025.202605 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559

Impact of conversational context on gaze patterns of autistic and non-autistic adolescents / Amelia REES ; Julia MERTENS ; Emily ZANE in Research in Autism, 125 (July 2025)  

Public ISBD [article]  inResearch in Autism > 125 (July 2025) . - p.202606 Titre : Impact of conversational context on gaze patterns of autistic and non-autistic adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Amelia REES, Auteur ; Julia MERTENS, Auteur ; Emily ZANE, Auteur Article en page(s) : p.202606 Langues : Anglais (eng) Mots-clés : Autism  Conversation  Eye gaze  Cognition Index. décimale : PER Périodiques Résumé : Purpose Few studies of social gaze by autistic individuals have focused on live interactions and those studies have been limited to conversations with a single partner. The purpose of this study was to investigate the impact of conversational variations in cognitive load on social gaze of autistic and non-autistic adolescents while engaging with two conversation partners. Methods Participants engaged in a conversation where two research assistants (RAs) and the participant each shared personal memories and engaged with each other through question asking and commenting. We used eye-tracking glasses to record and analyze participants" gaze in response to two questions: One question was open-ended and referenced an unusual topic (high cognitive demand), while the other question required a simple yes or no response about a common topic (low cognitive demand). Results Non-autistic adolescents gazed more at the faces of either RA than their autistic peers. Both participant groups gazed more at the face of the RA who had just asked a question. Post-hoc pairwise comparisons revealed that non-autistic participants gazed significantly more at the RA asking the yes/no question than the RA asking the open-ended question condition, but autistic participants showed no such gaze difference across question type. Conclusion These findings indicate a pattern of interactional gaze that is influenced not only by neurotype, but also by conversational features, such as the difficulty of the question and the overall social demands of interacting with more than one person. En ligne : https://doi.org/10.1016/j.reia.2025.202606 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] Impact of conversational context on gaze patterns of autistic and non-autistic adolescents [Texte imprimé et/ou numérique] / Amelia REES, Auteur ; Julia MERTENS, Auteur ; Emily ZANE, Auteur . - p.202606. Langues : Anglais (eng) in Research in Autism > 125 (July 2025) . - p.202606 Mots-clés : Autism  Conversation  Eye gaze  Cognition Index. décimale : PER Périodiques Résumé : Purpose Few studies of social gaze by autistic individuals have focused on live interactions and those studies have been limited to conversations with a single partner. The purpose of this study was to investigate the impact of conversational variations in cognitive load on social gaze of autistic and non-autistic adolescents while engaging with two conversation partners. Methods Participants engaged in a conversation where two research assistants (RAs) and the participant each shared personal memories and engaged with each other through question asking and commenting. We used eye-tracking glasses to record and analyze participants" gaze in response to two questions: One question was open-ended and referenced an unusual topic (high cognitive demand), while the other question required a simple yes or no response about a common topic (low cognitive demand). Results Non-autistic adolescents gazed more at the faces of either RA than their autistic peers. Both participant groups gazed more at the face of the RA who had just asked a question. Post-hoc pairwise comparisons revealed that non-autistic participants gazed significantly more at the RA asking the yes/no question than the RA asking the open-ended question condition, but autistic participants showed no such gaze difference across question type. Conclusion These findings indicate a pattern of interactional gaze that is influenced not only by neurotype, but also by conversational features, such as the difficulty of the question and the overall social demands of interacting with more than one person. En ligne : https://doi.org/10.1016/j.reia.2025.202606 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559

The effect of a 12-week ball combination training program on physical fitness and motor disorders in children with autism spectrum disorders: An experimental study / Haiyong MAO ; Yufei LIU ; Kelong CAI ; Aiguo CHEN in Research in Autism, 125 (July 2025)  

Public ISBD [article]  inResearch in Autism > 125 (July 2025) . - p.202607 Titre : The effect of a 12-week ball combination training program on physical fitness and motor disorders in children with autism spectrum disorders: An experimental study Type de document : Texte imprimé et/ou numérique Auteurs : Haiyong MAO, Auteur ; Yufei LIU, Auteur ; Kelong CAI, Auteur ; Aiguo CHEN, Auteur Article en page(s) : p.202607 Langues : Anglais (eng) Mots-clés : Ball  Physical fitness  Motor disorder  Children  Autism spectrum disorder (ASD) Index. décimale : PER Périodiques Résumé : This investigation examined the effects of a 12-week ball combination training program (BCTP) on physical fitness and motor disorders in children with autism spectrum disorder (ASD). The study employed a 2 * 2 mixed experimental design, 55 children with ASD who received their conventional rehabilitation program (ABA) were assigned to either a BCTP group (n = 28) or a control group (n = 27). The BCTP group was asked to engage in an additional 12-week BCTP (five days per week, one session per day, and forty-five minutes per session), while the control group was instructed to maintain their daily activities. The physical fitness test and the Movement Assessment Battery for Children - Second Edition (MABC-2) test were performed before and after the intervention. Results indicate that the 12-week BCTP facilitated improvement in the physical fitness test, particularly in tennis ball throw(p < 0.05). Additionally, in terms of motor disorders, children in the BCTP group demonstrated improvement in aiming & catching(p < 0.05), whereas no such changes were found in the control group. These findings suggest that the 12-week BCTP could improve upper limb of throwing ability and aiming & catching in children with ASD. While both the experimental and control groups showed increases in post-test scores for other aspects of physical fitness and motor disorders, no significant differences were found between the groups. Therefore, the use of BCTP could be selected as an effective intervention according to the actual situation of children with ASD. En ligne : https://doi.org/10.1016/j.reia.2025.202607 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] The effect of a 12-week ball combination training program on physical fitness and motor disorders in children with autism spectrum disorders: An experimental study [Texte imprimé et/ou numérique] / Haiyong MAO, Auteur ; Yufei LIU, Auteur ; Kelong CAI, Auteur ; Aiguo CHEN, Auteur . - p.202607. Langues : Anglais (eng) in Research in Autism > 125 (July 2025) . - p.202607 Mots-clés : Ball  Physical fitness  Motor disorder  Children  Autism spectrum disorder (ASD) Index. décimale : PER Périodiques Résumé : This investigation examined the effects of a 12-week ball combination training program (BCTP) on physical fitness and motor disorders in children with autism spectrum disorder (ASD). The study employed a 2 * 2 mixed experimental design, 55 children with ASD who received their conventional rehabilitation program (ABA) were assigned to either a BCTP group (n = 28) or a control group (n = 27). The BCTP group was asked to engage in an additional 12-week BCTP (five days per week, one session per day, and forty-five minutes per session), while the control group was instructed to maintain their daily activities. The physical fitness test and the Movement Assessment Battery for Children - Second Edition (MABC-2) test were performed before and after the intervention. Results indicate that the 12-week BCTP facilitated improvement in the physical fitness test, particularly in tennis ball throw(p < 0.05). Additionally, in terms of motor disorders, children in the BCTP group demonstrated improvement in aiming & catching(p < 0.05), whereas no such changes were found in the control group. These findings suggest that the 12-week BCTP could improve upper limb of throwing ability and aiming & catching in children with ASD. While both the experimental and control groups showed increases in post-test scores for other aspects of physical fitness and motor disorders, no significant differences were found between the groups. Therefore, the use of BCTP could be selected as an effective intervention according to the actual situation of children with ASD. En ligne : https://doi.org/10.1016/j.reia.2025.202607 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559

Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in patients with autism and attention deficit hyperactivity disorder / Raziyeh GHORBANZADEH ; Brandon LUCKE-WOLD ; Rebecca ZELMANOVICH ; Arshin GHAEDI ; Sahar SANJARIAN ; Peyman MOKARIAN ; Shokoufeh KHANZADEH in Research in Autism, 125 (July 2025)  

Public ISBD [article]  inResearch in Autism > 125 (July 2025) . - p.202608 Titre : Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in patients with autism and attention deficit hyperactivity disorder Type de document : Texte imprimé et/ou numérique Auteurs : Raziyeh GHORBANZADEH, Auteur ; Brandon LUCKE-WOLD, Auteur ; Rebecca ZELMANOVICH, Auteur ; Arshin GHAEDI, Auteur ; Sahar SANJARIAN, Auteur ; Peyman MOKARIAN, Auteur ; Shokoufeh KHANZADEH, Auteur Article en page(s) : p.202608 Langues : Anglais (eng) Mots-clés : Neutrophil to lymphocyte ratio  NLR  PLR  Autism  Attention deficit hyperactivity disorder  Meta-analysis Index. décimale : PER Périodiques Résumé : Background We conducted a systematic review and meta-analysis according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines to determine the association of neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR), as the indicators of inflammatory stress response, with Autism Spectrum Disorder (ASD) and attention deficit hyperactivity disorder (ADHD). Methods Two investigators searched the relevant articles of PubMed, Scopus, and Web of Science from the establishment of the database to September 7, 2024. The quality of the included literature was evaluated according to the Newcastle-Ottawa scale (NOS). The results are reflected in the form of standard mean difference (SMD) and 95 % confidence interval (CI). Results Finally, 17 articles were included in our study. The results showed that the level of NLR in peripheral blood of patients was significantly higher than that of the healthy group in either ADHD group (SMD=0.48, 95 % CI=0.17-0.79) or ASD group (SMD=0.39, 95 % CI=?0.04-0.74). Also, the PLR level in patients was significantly higher than that of healthy controls in ADHD group (SMD=0.41, 95 % CI=0.15-0.67), but not in ASD group (SMD=0.21, 95 % CI=?0.14-0.56). Conclusion Our findings suggest NLR and PLR be the potential markers of disease while also implicating a role for inflammation in the underlying pathophysiology. En ligne : https://doi.org/10.1016/j.reia.2025.202608 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in patients with autism and attention deficit hyperactivity disorder [Texte imprimé et/ou numérique] / Raziyeh GHORBANZADEH, Auteur ; Brandon LUCKE-WOLD, Auteur ; Rebecca ZELMANOVICH, Auteur ; Arshin GHAEDI, Auteur ; Sahar SANJARIAN, Auteur ; Peyman MOKARIAN, Auteur ; Shokoufeh KHANZADEH, Auteur . - p.202608. Langues : Anglais (eng) in Research in Autism > 125 (July 2025) . - p.202608 Mots-clés : Neutrophil to lymphocyte ratio  NLR  PLR  Autism  Attention deficit hyperactivity disorder  Meta-analysis Index. décimale : PER Périodiques Résumé : Background We conducted a systematic review and meta-analysis according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines to determine the association of neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR), as the indicators of inflammatory stress response, with Autism Spectrum Disorder (ASD) and attention deficit hyperactivity disorder (ADHD). Methods Two investigators searched the relevant articles of PubMed, Scopus, and Web of Science from the establishment of the database to September 7, 2024. The quality of the included literature was evaluated according to the Newcastle-Ottawa scale (NOS). The results are reflected in the form of standard mean difference (SMD) and 95 % confidence interval (CI). Results Finally, 17 articles were included in our study. The results showed that the level of NLR in peripheral blood of patients was significantly higher than that of the healthy group in either ADHD group (SMD=0.48, 95 % CI=0.17-0.79) or ASD group (SMD=0.39, 95 % CI=?0.04-0.74). Also, the PLR level in patients was significantly higher than that of healthy controls in ADHD group (SMD=0.41, 95 % CI=0.15-0.67), but not in ASD group (SMD=0.21, 95 % CI=?0.14-0.56). Conclusion Our findings suggest NLR and PLR be the potential markers of disease while also implicating a role for inflammation in the underlying pathophysiology. En ligne : https://doi.org/10.1016/j.reia.2025.202608 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559

Association between urinary toxic and essential metals exposure and autism in children / Josefa CANALS-SANS ; Paula MORALES-HIDALGO ; Victoria ARIJA in Research in Autism, 125 (July 2025)  

Public ISBD [article]  inResearch in Autism > 125 (July 2025) . - p.202616 Titre : Association between urinary toxic and essential metals exposure and autism in children Type de document : Texte imprimé et/ou numérique Auteurs : Josefa CANALS-SANS, Auteur ; Paula MORALES-HIDALGO, Auteur ; Victoria ARIJA, Auteur Article en page(s) : p.202616 Langues : Anglais (eng) Mots-clés : Heavy metals  Autism  Neurodevelopment conditions  Children Index. décimale : PER Périodiques Résumé : Autism has a multifactorial origin, with genetic factors playing a significant role, while various environmental factors, including early exposure to toxic or essential metals, have been associated with an increased likelihood in children. The current study analysed the association between 15 different essential and heavy metals and autism among Spanish school children. Urine samples from a total of 108 children (autism group: N = 42; non-autism group: N = 66) between the ages of 5-16 years were analysed. Logistic regressions, adjusted for sex, age, BMI, SES, and diet quality, were performed using a categorical comparison of metal concentrations in quartiles, with the first quartile as a reference. Significant associations were found in the fourth quartile for copper (Cu) (aOR 9.45; CI: 1.89-48.02), third quartile for lead (Pb) (aOR 5.59; CI 1.36-22.94) and in the 75th percentile for manganese (Mn) (aOR 12.50; CI 3.27-47.72). Furthermore, Mn exposure was associated with more pronounced differences in social cognition, as measured by the Social Responsiveness Scale-2nd edition (? = 22.04, p = .038). However, no significant associations were found with other essential or heavy metals. This study provides significant insights into the association between metal exposure and autism in school-aged children, emphasising the need for further research to better understand and mitigate the impact of environmental influences on children?s health and development. En ligne : https://doi.org/10.1016/j.reia.2025.202616 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] Association between urinary toxic and essential metals exposure and autism in children [Texte imprimé et/ou numérique] / Josefa CANALS-SANS, Auteur ; Paula MORALES-HIDALGO, Auteur ; Victoria ARIJA, Auteur . - p.202616. Langues : Anglais (eng) in Research in Autism > 125 (July 2025) . - p.202616 Mots-clés : Heavy metals  Autism  Neurodevelopment conditions  Children Index. décimale : PER Périodiques Résumé : Autism has a multifactorial origin, with genetic factors playing a significant role, while various environmental factors, including early exposure to toxic or essential metals, have been associated with an increased likelihood in children. The current study analysed the association between 15 different essential and heavy metals and autism among Spanish school children. Urine samples from a total of 108 children (autism group: N = 42; non-autism group: N = 66) between the ages of 5-16 years were analysed. Logistic regressions, adjusted for sex, age, BMI, SES, and diet quality, were performed using a categorical comparison of metal concentrations in quartiles, with the first quartile as a reference. Significant associations were found in the fourth quartile for copper (Cu) (aOR 9.45; CI: 1.89-48.02), third quartile for lead (Pb) (aOR 5.59; CI 1.36-22.94) and in the 75th percentile for manganese (Mn) (aOR 12.50; CI 3.27-47.72). Furthermore, Mn exposure was associated with more pronounced differences in social cognition, as measured by the Social Responsiveness Scale-2nd edition (? = 22.04, p = .038). However, no significant associations were found with other essential or heavy metals. This study provides significant insights into the association between metal exposure and autism in school-aged children, emphasising the need for further research to better understand and mitigate the impact of environmental influences on children?s health and development. En ligne : https://doi.org/10.1016/j.reia.2025.202616 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559

Is there an optimal self-report measure to investigate autism-related sex differences? / Lucy A. LIVINGSTON ; Punit SHAH in Research in Autism, 125 (July 2025)  

Public ISBD [article]  inResearch in Autism > 125 (July 2025) . - p.202617 Titre : Is there an optimal self-report measure to investigate autism-related sex differences? Type de document : Texte imprimé et/ou numérique Auteurs : Lucy A. LIVINGSTON, Auteur ; Punit SHAH, Auteur Article en page(s) : p.202617 Langues : Anglais (eng) Mots-clés : Autism  Autistic Traits  Gender  Sex Index. décimale : PER Périodiques Résumé : There is growing research interest in autism-related sex differences. Many behavioural and cognitive sex differences have been identified, with implications for research and clinical practice. Much of this research has relied on self-report autism measures, which are assumed to measure autistic traits equally in males and females. However, robust evidence for this assumption is lacking. Previous findings have not been replicated and no study has directly compared sex differences across multiple self-report autism measures in the same sample. To address this gap in research, a large sample of adults (N = 1000, 500 female) completed a series of self-report autism measures (AQ-50, ?28, ?26, ?20, ?10, ?9, BAPQ, CATI). Following pre-registered measurement invariance analyses, only the AQ-9, AQ-28, and CATI showed good-to-acceptable invariance to sex when specifying a multi-factor structure, and all 8 measures showed non-invariance to sex when capturing a general autism construct. We discuss the implications of these findings for investigating autism-related sex differences in future research. En ligne : https://doi.org/10.1016/j.reia.2025.202617 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] Is there an optimal self-report measure to investigate autism-related sex differences? [Texte imprimé et/ou numérique] / Lucy A. LIVINGSTON, Auteur ; Punit SHAH, Auteur . - p.202617. Langues : Anglais (eng) in Research in Autism > 125 (July 2025) . - p.202617 Mots-clés : Autism  Autistic Traits  Gender  Sex Index. décimale : PER Périodiques Résumé : There is growing research interest in autism-related sex differences. Many behavioural and cognitive sex differences have been identified, with implications for research and clinical practice. Much of this research has relied on self-report autism measures, which are assumed to measure autistic traits equally in males and females. However, robust evidence for this assumption is lacking. Previous findings have not been replicated and no study has directly compared sex differences across multiple self-report autism measures in the same sample. To address this gap in research, a large sample of adults (N = 1000, 500 female) completed a series of self-report autism measures (AQ-50, ?28, ?26, ?20, ?10, ?9, BAPQ, CATI). Following pre-registered measurement invariance analyses, only the AQ-9, AQ-28, and CATI showed good-to-acceptable invariance to sex when specifying a multi-factor structure, and all 8 measures showed non-invariance to sex when capturing a general autism construct. We discuss the implications of these findings for investigating autism-related sex differences in future research. En ligne : https://doi.org/10.1016/j.reia.2025.202617 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559

Behavioral and neural interrelationships of sensory difficulties, intolerance of uncertainty, and anxiety in autistic children / Kelsey TINDALL ; Don ROJAS in Research in Autism, 125 (July 2025)  

Public ISBD [article]  inResearch in Autism > 125 (July 2025) . - p.202618 Titre : Behavioral and neural interrelationships of sensory difficulties, intolerance of uncertainty, and anxiety in autistic children Type de document : Texte imprimé et/ou numérique Auteurs : Kelsey TINDALL, Auteur ; Don ROJAS, Auteur Article en page(s) : p.202618 Langues : Anglais (eng) Mots-clés : Autism  Anxiety  Sensory processing  Intolerance of uncertainty  Prediction  Cerebellum  Sensory cortex  Amygdala Index. décimale : PER Périodiques Résumé : Purpose Autistic children often experience higher levels of sensory difficulties and anxiety, compared to their non-autistic counterparts. Available evidence suggests that intolerance of uncertainty (IU) mediates the relationship between these factors. We aimed to further the examination of the interrelationship between these phenomena, as well as their underlying neural mechanisms, in children. Methods 30 autistic children (ages 6-11 years) and 26 age-matched neurotypical (NT) peers participated in resting-state fMRI, as well as various behavioral assessments of sensory processing, anxiety, and IU. Results Between-groups comparisons of behavioral scores showed higher levels of sensory processing differences, anxiety, and IU in autistic children. Mediation analysis also revealed that IU was a significant mediator between sensory difficulties and anxiety in this group. Network connectivity findings showed that connectivity between sensory cortices and cerebellar, higher order sensory, and limbic regions (esp. amygdala) were significantly correlated with sensory processing, anxiety, and IU. Conclusion We report novel behavioral and neurophysiologic findings concerning important interrelationships in autism. Our findings may be related to predictive coding accounts of autism. Our results have the potential to inform future clinical practice, in that addressing sensory and IU difficulties has the potential to lead to improvements in anxiety in autistic children. En ligne : https://doi.org/10.1016/j.reia.2025.202618 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] Behavioral and neural interrelationships of sensory difficulties, intolerance of uncertainty, and anxiety in autistic children [Texte imprimé et/ou numérique] / Kelsey TINDALL, Auteur ; Don ROJAS, Auteur . - p.202618. Langues : Anglais (eng) in Research in Autism > 125 (July 2025) . - p.202618 Mots-clés : Autism  Anxiety  Sensory processing  Intolerance of uncertainty  Prediction  Cerebellum  Sensory cortex  Amygdala Index. décimale : PER Périodiques Résumé : Purpose Autistic children often experience higher levels of sensory difficulties and anxiety, compared to their non-autistic counterparts. Available evidence suggests that intolerance of uncertainty (IU) mediates the relationship between these factors. We aimed to further the examination of the interrelationship between these phenomena, as well as their underlying neural mechanisms, in children. Methods 30 autistic children (ages 6-11 years) and 26 age-matched neurotypical (NT) peers participated in resting-state fMRI, as well as various behavioral assessments of sensory processing, anxiety, and IU. Results Between-groups comparisons of behavioral scores showed higher levels of sensory processing differences, anxiety, and IU in autistic children. Mediation analysis also revealed that IU was a significant mediator between sensory difficulties and anxiety in this group. Network connectivity findings showed that connectivity between sensory cortices and cerebellar, higher order sensory, and limbic regions (esp. amygdala) were significantly correlated with sensory processing, anxiety, and IU. Conclusion We report novel behavioral and neurophysiologic findings concerning important interrelationships in autism. Our findings may be related to predictive coding accounts of autism. Our results have the potential to inform future clinical practice, in that addressing sensory and IU difficulties has the potential to lead to improvements in anxiety in autistic children. En ligne : https://doi.org/10.1016/j.reia.2025.202618 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559

Brief report: Fraudulent data responses as a major threat to validity in online autism research - Case studies from four independent research teams / Patrick DWYER ; Elizabeth A. KAPLAN-KAHN ; Kaitlin PROCTOR ; Ava GURBA ; Hannah E. MORTON in Research in Autism, 125 (July 2025)  

Public ISBD [article]  inResearch in Autism > 125 (July 2025) . - p.202619 Titre : Brief report: Fraudulent data responses as a major threat to validity in online autism research - Case studies from four independent research teams Type de document : Texte imprimé et/ou numérique Auteurs : Patrick DWYER, Auteur ; Elizabeth A. KAPLAN-KAHN, Auteur ; Kaitlin PROCTOR, Auteur ; Ava GURBA, Auteur ; Hannah E. MORTON, Auteur Article en page(s) : p.202619 Langues : Anglais (eng) Mots-clés : Online methods  Fraudulent responses  Data integrity  Case studies  Bots  Scammers  Autism research Index. décimale : PER Périodiques Résumé : Purpose The growing popularity of online research increases risks of fraudulent data that threaten the validity of findings. Autism research is particularly susceptible, as digital methods are frequently used to enhance inclusivity and accessibility. Methods Here we examine this vulnerability to bot-generated data and impersonation by scammers, which can jeopardize the integrity of study results. Results Four case studies are presented from independent research teams who encountered fraudulent participation. Each team used a variety of strategies to detect, address, and prevent these issues. Conclusion Our discussion emphasizes the importance of balancing the need for ethical inclusivity, particularly for autistic people who may benefit from online participation options, with necessary data integrity protections.We emphasize the role of proactive and adaptable safeguards in mitigating threats posed by fraudulent responses without inadvertently limiting access for legitimate participants. Finally, we offer practical recommendations for autism researchers to mitigate validity threats. En ligne : https://doi.org/10.1016/j.reia.2025.202619 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] Brief report: Fraudulent data responses as a major threat to validity in online autism research - Case studies from four independent research teams [Texte imprimé et/ou numérique] / Patrick DWYER, Auteur ; Elizabeth A. KAPLAN-KAHN, Auteur ; Kaitlin PROCTOR, Auteur ; Ava GURBA, Auteur ; Hannah E. MORTON, Auteur . - p.202619. Langues : Anglais (eng) in Research in Autism > 125 (July 2025) . - p.202619 Mots-clés : Online methods  Fraudulent responses  Data integrity  Case studies  Bots  Scammers  Autism research Index. décimale : PER Périodiques Résumé : Purpose The growing popularity of online research increases risks of fraudulent data that threaten the validity of findings. Autism research is particularly susceptible, as digital methods are frequently used to enhance inclusivity and accessibility. Methods Here we examine this vulnerability to bot-generated data and impersonation by scammers, which can jeopardize the integrity of study results. Results Four case studies are presented from independent research teams who encountered fraudulent participation. Each team used a variety of strategies to detect, address, and prevent these issues. Conclusion Our discussion emphasizes the importance of balancing the need for ethical inclusivity, particularly for autistic people who may benefit from online participation options, with necessary data integrity protections.We emphasize the role of proactive and adaptable safeguards in mitigating threats posed by fraudulent responses without inadvertently limiting access for legitimate participants. Finally, we offer practical recommendations for autism researchers to mitigate validity threats. En ligne : https://doi.org/10.1016/j.reia.2025.202619 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559

Visual-motor integration and visual perception in preschool children with autism spectrum disorder / I. Jou CHI ; Yu-Ru JIN ; Shin Ying CHU ; Ling-Yi LIN in Research in Autism, 125 (July 2025)  

Public ISBD [article]  inResearch in Autism > 125 (July 2025) . - p.202620 Titre : Visual-motor integration and visual perception in preschool children with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : I. Jou CHI, Auteur ; Yu-Ru JIN, Auteur ; Shin Ying CHU, Auteur ; Ling-Yi LIN, Auteur Article en page(s) : p.202620 Langues : Anglais (eng) Mots-clés : Autism  Visual-motor integration  Eye-hand coordination  Copying  Visual perception Index. décimale : PER Périodiques Résumé : A substantial number of children and adolescents with autism spectrum disorder (ASD) experience difficulties in performing visual-motor integration (VMI) related tasks and visual perception skills. Given the documented challenges in VMI and visual perception among children with ASD, limited research on VMI and visual perception in young children with ASD underscores the need for further investigation. We aimed to investigate the differences in performance on VMI and visual perception and their relationships between preschool children with ASD and typical development (TD). We recruited a total of 110 preschool children, including 60 with ASD and 50 TD children, with an average age of 60.7 months. Results revealed that children with ASD consistently showed lower performance in both visual-motor integration and visual perception compared to TD children. Notably, four-year-old autistic children showed an apparent difference in the spatial relationship scores from TD peers. However, four-year-old children with ASD had similar performance in VMI and visual perception tests compared to TD children. For five-year-olds with ASD, performance in VMI and VP was significantly lower than that of TD peers, except in the visual closure test. For children with ASD, VMI was significantly correlated with sequencing and complex processes in visual perception (e.g., sequential memory and visual closure), in addition to basic processes such as visual discrimination, visual memory, and spatial relationships. These findings highlight the need for occupational therapy interventions aimed at improving the VMI and visual perception abilities of preschool children with ASD. En ligne : https://doi.org/10.1016/j.reia.2025.202620 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] Visual-motor integration and visual perception in preschool children with autism spectrum disorder [Texte imprimé et/ou numérique] / I. Jou CHI, Auteur ; Yu-Ru JIN, Auteur ; Shin Ying CHU, Auteur ; Ling-Yi LIN, Auteur . - p.202620. Langues : Anglais (eng) in Research in Autism > 125 (July 2025) . - p.202620 Mots-clés : Autism  Visual-motor integration  Eye-hand coordination  Copying  Visual perception Index. décimale : PER Périodiques Résumé : A substantial number of children and adolescents with autism spectrum disorder (ASD) experience difficulties in performing visual-motor integration (VMI) related tasks and visual perception skills. Given the documented challenges in VMI and visual perception among children with ASD, limited research on VMI and visual perception in young children with ASD underscores the need for further investigation. We aimed to investigate the differences in performance on VMI and visual perception and their relationships between preschool children with ASD and typical development (TD). We recruited a total of 110 preschool children, including 60 with ASD and 50 TD children, with an average age of 60.7 months. Results revealed that children with ASD consistently showed lower performance in both visual-motor integration and visual perception compared to TD children. Notably, four-year-old autistic children showed an apparent difference in the spatial relationship scores from TD peers. However, four-year-old children with ASD had similar performance in VMI and visual perception tests compared to TD children. For five-year-olds with ASD, performance in VMI and VP was significantly lower than that of TD peers, except in the visual closure test. For children with ASD, VMI was significantly correlated with sequencing and complex processes in visual perception (e.g., sequential memory and visual closure), in addition to basic processes such as visual discrimination, visual memory, and spatial relationships. These findings highlight the need for occupational therapy interventions aimed at improving the VMI and visual perception abilities of preschool children with ASD. En ligne : https://doi.org/10.1016/j.reia.2025.202620 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559

Association between joint attention and autism traits in young adults: A gaze-contingent eye-tracking study / Hedda MEADAN ; Yan XIA ; Frederick SHIC in Research in Autism, 125 (July 2025)  

Public ISBD [article]  inResearch in Autism > 125 (July 2025) . - p.202622 Titre : Association between joint attention and autism traits in young adults: A gaze-contingent eye-tracking study Type de document : Texte imprimé et/ou numérique Auteurs : Hedda MEADAN, Auteur ; Yan XIA, Auteur ; Frederick SHIC, Auteur Article en page(s) : p.202622 Langues : Anglais (eng) Mots-clés : Adulthood  Autism  Eye tracking  Gaze contingency  Joint attention Index. décimale : PER Périodiques Résumé : Background The Interactive Eye Tracking for Joint Attention (IET-JA), a child-focused battery consisting of video-format gaze-contingent eye-tracking tasks featuring a human communication partner, was developed to address gaps in eye-tracking research on JA in autistic children. Although JA research has often concentrated on younger populations due to its early developmental significance, studies indicate that JA difficulties associated with autism persist into adulthood, highlighting the value of examining these traits later in life. Thus, this study adapted the IET-JA for adolescents and adults (IET-JA-A) by incorporating additional attentional demands to introduce controlled attentional variations and explore whether these interactive eye-tracking measures of JA associate with autism traits in adulthood. Methods A total of 81 young adults (Mage = 19.32 years, range = 18-24 years), with a broad range of autism traits, completed the IET-JA-A. Generalized and linear mixed modeling were employed to address the aim. Results The IET-JA-A measures of responding to joint attention and initiating joint attention to comment/reference (protodeclarative) were associated with autism traits, while the IET-JA-A measures of initiating joint attention to request (protoimperative) were not associated with autism traits. Conclusions Findings advance our understanding of JA linked with autism traits in adulthood and showcase the feasibility of interactive eye-tracking methodologies in JA research. Limitations and implications for research are discussed. En ligne : https://doi.org/10.1016/j.reia.2025.202622 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] Association between joint attention and autism traits in young adults: A gaze-contingent eye-tracking study [Texte imprimé et/ou numérique] / Hedda MEADAN, Auteur ; Yan XIA, Auteur ; Frederick SHIC, Auteur . - p.202622. Langues : Anglais (eng) in Research in Autism > 125 (July 2025) . - p.202622 Mots-clés : Adulthood  Autism  Eye tracking  Gaze contingency  Joint attention Index. décimale : PER Périodiques Résumé : Background The Interactive Eye Tracking for Joint Attention (IET-JA), a child-focused battery consisting of video-format gaze-contingent eye-tracking tasks featuring a human communication partner, was developed to address gaps in eye-tracking research on JA in autistic children. Although JA research has often concentrated on younger populations due to its early developmental significance, studies indicate that JA difficulties associated with autism persist into adulthood, highlighting the value of examining these traits later in life. Thus, this study adapted the IET-JA for adolescents and adults (IET-JA-A) by incorporating additional attentional demands to introduce controlled attentional variations and explore whether these interactive eye-tracking measures of JA associate with autism traits in adulthood. Methods A total of 81 young adults (Mage = 19.32 years, range = 18-24 years), with a broad range of autism traits, completed the IET-JA-A. Generalized and linear mixed modeling were employed to address the aim. Results The IET-JA-A measures of responding to joint attention and initiating joint attention to comment/reference (protodeclarative) were associated with autism traits, while the IET-JA-A measures of initiating joint attention to request (protoimperative) were not associated with autism traits. Conclusions Findings advance our understanding of JA linked with autism traits in adulthood and showcase the feasibility of interactive eye-tracking methodologies in JA research. Limitations and implications for research are discussed. En ligne : https://doi.org/10.1016/j.reia.2025.202622 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559

Predictors of synchronized verbalizations in mothers of children at elevated likelihood of autism / Ines BRYS ; Lotte VAN ESCH ; Melinda MADAREVIC ; Floor MOERMAN ; Lyssa DE VRIES ; Petra WARREYN ; Jean STEYAERT ; Herbert ROEYERS ; Ilse NOENS in Research in Autism, 125 (July 2025)  

Public ISBD [article]  inResearch in Autism > 125 (July 2025) . - p.202623 Titre : Predictors of synchronized verbalizations in mothers of children at elevated likelihood of autism Type de document : Texte imprimé et/ou numérique Auteurs : Ines BRYS, Auteur ; Lotte VAN ESCH, Auteur ; Melinda MADAREVIC, Auteur ; Floor MOERMAN, Auteur ; Lyssa DE VRIES, Auteur ; Petra WARREYN, Auteur ; Jean STEYAERT, Auteur ; Herbert ROEYERS, Auteur ; Ilse NOENS, Auteur Article en page(s) : p.202623 Langues : Anglais (eng) Mots-clés : Parent behaviors  Parent-child interactions  Language development  Autism  Elevated likelihood  Siblings  Preterms Index. décimale : PER Périodiques Résumé : Background Multiple studies indicated that parents stimulate their children?s language, development by synchronizing verbal input to their children?s focus of attention.Interactions between parents and children are assumed to be transactional, meaning, that both parent and child influence each other?s behaviors. Yet, the relationship, between parents" synchronized verbalizations and child development is almost. exclusively studied in a one-directional manner. We therefore investigated the, predictive value of child development (i.e. language and cognitive abilities and autism, research diagnosis) on parents" synchronized verbalizations. Methods We observed, 93 mother-child dyads containing children at elevated likelihood of autism (i.e. siblings, and preterms). Child language and cognitive abilities were assessed around 10, months, parenting behaviors around 14 months, and best estimate research diagnoses, were given around 36 months. We ran hierarchical linear regression models to predict, (a) all synchronized verbalizations and (b) synchronized verbalizations which were, posed in a non-directive manner. Results Early language abilities, but not cognitive, abilities or autism research diagnosis predicted mothers" synchronized verbalizations. Results were similar for both operationalizations of synchronized verbalizations (i.e. all and non-directive). Our findings indicate that the current uni-directional view might need to be expanded to a more transactional model. En ligne : https://doi.org/10.1016/j.reia.2025.202623 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] Predictors of synchronized verbalizations in mothers of children at elevated likelihood of autism [Texte imprimé et/ou numérique] / Ines BRYS, Auteur ; Lotte VAN ESCH, Auteur ; Melinda MADAREVIC, Auteur ; Floor MOERMAN, Auteur ; Lyssa DE VRIES, Auteur ; Petra WARREYN, Auteur ; Jean STEYAERT, Auteur ; Herbert ROEYERS, Auteur ; Ilse NOENS, Auteur . - p.202623. Langues : Anglais (eng) in Research in Autism > 125 (July 2025) . - p.202623 Mots-clés : Parent behaviors  Parent-child interactions  Language development  Autism  Elevated likelihood  Siblings  Preterms Index. décimale : PER Périodiques Résumé : Background Multiple studies indicated that parents stimulate their children?s language, development by synchronizing verbal input to their children?s focus of attention.Interactions between parents and children are assumed to be transactional, meaning, that both parent and child influence each other?s behaviors. Yet, the relationship, between parents" synchronized verbalizations and child development is almost. exclusively studied in a one-directional manner. We therefore investigated the, predictive value of child development (i.e. language and cognitive abilities and autism, research diagnosis) on parents" synchronized verbalizations. Methods We observed, 93 mother-child dyads containing children at elevated likelihood of autism (i.e. siblings, and preterms). Child language and cognitive abilities were assessed around 10, months, parenting behaviors around 14 months, and best estimate research diagnoses, were given around 36 months. We ran hierarchical linear regression models to predict, (a) all synchronized verbalizations and (b) synchronized verbalizations which were, posed in a non-directive manner. Results Early language abilities, but not cognitive, abilities or autism research diagnosis predicted mothers" synchronized verbalizations. Results were similar for both operationalizations of synchronized verbalizations (i.e. all and non-directive). Our findings indicate that the current uni-directional view might need to be expanded to a more transactional model. En ligne : https://doi.org/10.1016/j.reia.2025.202623 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559

Effects of music listening therapy on reducing cortisol levels and DNA damage in children and adolescents with autism spectrum disorder: A non-pharmacological pilot study / Patrícia MOLZ ; Diene DA SILVA SCHLICKMANN ; Caroline DOS SANTOS ; Daniel PRÁ ; Sâmara Bittencourt BERGER ; Jane Dagmar Pollo RENNER ; Silvia Isabel Rech FRANKE in Research in Autism, 125 (July 2025)  

Public ISBD [article]  inResearch in Autism > 125 (July 2025) . - p.202624 Titre : Effects of music listening therapy on reducing cortisol levels and DNA damage in children and adolescents with autism spectrum disorder: A non-pharmacological pilot study Type de document : Texte imprimé et/ou numérique Auteurs : Patrícia MOLZ, Auteur ; Diene DA SILVA SCHLICKMANN, Auteur ; Caroline DOS SANTOS, Auteur ; Daniel PRÁ, Auteur ; Sâmara Bittencourt BERGER, Auteur ; Jane Dagmar Pollo RENNER, Auteur ; Silvia Isabel Rech FRANKE, Auteur Article en page(s) : p.202624 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Child  Adolescents  Music therapy  Stress  DNA damage Index. décimale : PER Périodiques Résumé : Background Music listening therapy may be a promising non-pharmacological strategy for reducing emotional stress in individuals with Autism Spectrum Disorder (ASD). However, its effects on DNA damage are not well understood. This pilot study investigated the effects of music listening therapy on cortisol levels and DNA damage in children and adolescents with ASD. Methods Participants listened to a selection of classical music daily for 30 days. Cortisol levels and DNA damage (measured by micronucleus frequency and nuclear buds) were assessed before and after the intervention. Results After one month, the pilot study did not find a significant reduction in cortisol levels. However, music listening therapy was associated with a reduction in DNA damage, as evidenced by a decrease in micronucleus frequency. Conclusions Our findings suggest that music listening therapy could be a promising non-pharmacological intervention for children and adolescents with ASD. En ligne : https://doi.org/10.1016/j.reia.2025.202624 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] Effects of music listening therapy on reducing cortisol levels and DNA damage in children and adolescents with autism spectrum disorder: A non-pharmacological pilot study [Texte imprimé et/ou numérique] / Patrícia MOLZ, Auteur ; Diene DA SILVA SCHLICKMANN, Auteur ; Caroline DOS SANTOS, Auteur ; Daniel PRÁ, Auteur ; Sâmara Bittencourt BERGER, Auteur ; Jane Dagmar Pollo RENNER, Auteur ; Silvia Isabel Rech FRANKE, Auteur . - p.202624. Langues : Anglais (eng) in Research in Autism > 125 (July 2025) . - p.202624 Mots-clés : Autism spectrum disorder  Child  Adolescents  Music therapy  Stress  DNA damage Index. décimale : PER Périodiques Résumé : Background Music listening therapy may be a promising non-pharmacological strategy for reducing emotional stress in individuals with Autism Spectrum Disorder (ASD). However, its effects on DNA damage are not well understood. This pilot study investigated the effects of music listening therapy on cortisol levels and DNA damage in children and adolescents with ASD. Methods Participants listened to a selection of classical music daily for 30 days. Cortisol levels and DNA damage (measured by micronucleus frequency and nuclear buds) were assessed before and after the intervention. Results After one month, the pilot study did not find a significant reduction in cortisol levels. However, music listening therapy was associated with a reduction in DNA damage, as evidenced by a decrease in micronucleus frequency. Conclusions Our findings suggest that music listening therapy could be a promising non-pharmacological intervention for children and adolescents with ASD. En ligne : https://doi.org/10.1016/j.reia.2025.202624 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559

Digital interventions for enhancing communication and collaboration in children with autism spectrum disorder: An integrative review / Moomin Ahmad RATHER in Research in Autism, 125 (July 2025)  

Public ISBD [article]  inResearch in Autism > 125 (July 2025) . - p.202625 Titre : Digital interventions for enhancing communication and collaboration in children with autism spectrum disorder: An integrative review Type de document : Texte imprimé et/ou numérique Auteurs : Moomin Ahmad RATHER, Auteur Article en page(s) : p.202625 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder  Digital interventions  Communication  Collaboration Mobile apps  Virtual reality  Robot-assisted therapy Index. décimale : PER Périodiques Résumé : Background Children with Autism Spectrum Disorder (ASD) often experience significant challenges in communication and collaboration. Traditional interventions, though beneficial, may require substantial resources and may not always accommodate the diverse sensory and cognitive needs of children with ASD. Digital interventions, including mobile applications, virtual reality (VR), and robot-assisted therapy, provide flexible and engaging alternatives by utilizing structured, interactive, and visually enriched environments tailored to the strengths of children with ASD. Method This integrative review, conducted following PRISMA guidelines, analyzed studies published between 2011 and 2022 to explore how various digital interventions support communication and collaboration skills in children with ASD. Eleven studies that met the inclusion criteria were selected from databases such as Google Scholar, ERIC, and PsycINFO. A qualitative synthesis of findings was performed, considering study methodologies, target skills, and reported outcomes. Results Findings suggest that mobile applications, particularly those incorporating speech-generating devices, facilitate verbal communication in younger children. Robot-assisted therapy has shown potential in enhancing nonverbal communication, such as eye contact and gestures, while VR and game-based learning promote collaborative behaviors like turn-taking and joint problem-solving. Although some studies reported effect sizes (e.g., Cohen?s d = 0.32 [0.12-0.51]), the heterogeneity in study designs and intervention types limits direct comparisons. Instead, trends across studies indicate promising advancements in digital support for social and communication development in children with ASD. Conclusion Digital interventions offer valuable opportunities for enhancing social and communication skills in children with ASD. While these tools complement traditional therapeutic approaches, variability in intervention designs and sample sizes suggests the need for further research to refine their implementation in educational and clinical settings. En ligne : https://doi.org/10.1016/j.reia.2025.202625 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] Digital interventions for enhancing communication and collaboration in children with autism spectrum disorder: An integrative review [Texte imprimé et/ou numérique] / Moomin Ahmad RATHER, Auteur . - p.202625. Langues : Anglais (eng) in Research in Autism > 125 (July 2025) . - p.202625 Mots-clés : Autism Spectrum Disorder  Digital interventions  Communication  Collaboration Mobile apps  Virtual reality  Robot-assisted therapy Index. décimale : PER Périodiques Résumé : Background Children with Autism Spectrum Disorder (ASD) often experience significant challenges in communication and collaboration. Traditional interventions, though beneficial, may require substantial resources and may not always accommodate the diverse sensory and cognitive needs of children with ASD. Digital interventions, including mobile applications, virtual reality (VR), and robot-assisted therapy, provide flexible and engaging alternatives by utilizing structured, interactive, and visually enriched environments tailored to the strengths of children with ASD. Method This integrative review, conducted following PRISMA guidelines, analyzed studies published between 2011 and 2022 to explore how various digital interventions support communication and collaboration skills in children with ASD. Eleven studies that met the inclusion criteria were selected from databases such as Google Scholar, ERIC, and PsycINFO. A qualitative synthesis of findings was performed, considering study methodologies, target skills, and reported outcomes. Results Findings suggest that mobile applications, particularly those incorporating speech-generating devices, facilitate verbal communication in younger children. Robot-assisted therapy has shown potential in enhancing nonverbal communication, such as eye contact and gestures, while VR and game-based learning promote collaborative behaviors like turn-taking and joint problem-solving. Although some studies reported effect sizes (e.g., Cohen?s d = 0.32 [0.12-0.51]), the heterogeneity in study designs and intervention types limits direct comparisons. Instead, trends across studies indicate promising advancements in digital support for social and communication development in children with ASD. Conclusion Digital interventions offer valuable opportunities for enhancing social and communication skills in children with ASD. While these tools complement traditional therapeutic approaches, variability in intervention designs and sample sizes suggests the need for further research to refine their implementation in educational and clinical settings. En ligne : https://doi.org/10.1016/j.reia.2025.202625 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559

Decreased central corpus callosum volume in autistic children is associated with repetitive behaviours and motor skills / Denis PERUZZO ; Filippo ARRIGONI ; Silvia BUSTI CECCARELLI ; Laura VILLA ; Elisa MANI ; Eleonora MAGGIONI ; Paolo BRAMBILLA ; Maria NOBILE ; Massimo MOLTENI ; Alessandro CRIPPA in Research in Autism, 125 (July 2025)  

Public ISBD [article]  inResearch in Autism > 125 (July 2025) . - p.202626 Titre : Decreased central corpus callosum volume in autistic children is associated with repetitive behaviours and motor skills Type de document : Texte imprimé et/ou numérique Auteurs : Denis PERUZZO, Auteur ; Filippo ARRIGONI, Auteur ; Silvia BUSTI CECCARELLI, Auteur ; Laura VILLA, Auteur ; Elisa MANI, Auteur ; Eleonora MAGGIONI, Auteur ; Paolo BRAMBILLA, Auteur ; Maria NOBILE, Auteur ; Massimo MOLTENI, Auteur ; Alessandro CRIPPA, Auteur Article en page(s) : p.202626 Langues : Anglais (eng) Mots-clés : Autism  Corpus callosum  Magnetic resonance imaging  Restricted repetitive behaviours  Motor skills Index. décimale : PER Périodiques Résumé : Introduction Along with the core characteristics of the condition, autistic individuals commonly experience motor coordination difficulties, potentially related to a reduced cortical connectivity. Being the largest human commissure, the corpus callosum (CC) plays an essential role in interhemispheric connectivity and has been often involved among autistic atypicalities. This study aimed to investigate the volumes of corpus callosum subregions in a group of drug-naïve, autistic children and to explore its possible associations with both core features and motor coordination skills. Methods Thirty-five autistic children (2.5-12 years) were compared with a group of 35 closely IQ-matched, non-autistic peers. CC was identified and segmented into five subregions using Freesurfer. Callosal volumes were compared between the two groups and correlated with parental ratings of core autistic features as assessed by the Social Responsiveness Scale and with motor features as assessed by the Developmental Coordination Disorder Questionnaire. Associations between CC volume and Autism Diagnostic Observation Schedule scores were also explored in autistic participants. Results Autistic children showed a reduced volume of the central segment of the CC, in the context of a comparable CC total volume. This reduction appeared to be correlated with symptoms of restricted and repetitive behaviours in autistic children. An association between Central CC volume and parental ratings of autistic mannerisms and motor skills was also found across participants, mostly driven by the non-autistic group. Conclusion These findings expand the current knowledge about the neural mechanisms underlying autism, suggesting that the reduced connectivity through the CC might have implications for both core autistic features and motor skills. En ligne : https://doi.org/10.1016/j.reia.2025.202626 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] Decreased central corpus callosum volume in autistic children is associated with repetitive behaviours and motor skills [Texte imprimé et/ou numérique] / Denis PERUZZO, Auteur ; Filippo ARRIGONI, Auteur ; Silvia BUSTI CECCARELLI, Auteur ; Laura VILLA, Auteur ; Elisa MANI, Auteur ; Eleonora MAGGIONI, Auteur ; Paolo BRAMBILLA, Auteur ; Maria NOBILE, Auteur ; Massimo MOLTENI, Auteur ; Alessandro CRIPPA, Auteur . - p.202626. Langues : Anglais (eng) in Research in Autism > 125 (July 2025) . - p.202626 Mots-clés : Autism  Corpus callosum  Magnetic resonance imaging  Restricted repetitive behaviours  Motor skills Index. décimale : PER Périodiques Résumé : Introduction Along with the core characteristics of the condition, autistic individuals commonly experience motor coordination difficulties, potentially related to a reduced cortical connectivity. Being the largest human commissure, the corpus callosum (CC) plays an essential role in interhemispheric connectivity and has been often involved among autistic atypicalities. This study aimed to investigate the volumes of corpus callosum subregions in a group of drug-naïve, autistic children and to explore its possible associations with both core features and motor coordination skills. Methods Thirty-five autistic children (2.5-12 years) were compared with a group of 35 closely IQ-matched, non-autistic peers. CC was identified and segmented into five subregions using Freesurfer. Callosal volumes were compared between the two groups and correlated with parental ratings of core autistic features as assessed by the Social Responsiveness Scale and with motor features as assessed by the Developmental Coordination Disorder Questionnaire. Associations between CC volume and Autism Diagnostic Observation Schedule scores were also explored in autistic participants. Results Autistic children showed a reduced volume of the central segment of the CC, in the context of a comparable CC total volume. This reduction appeared to be correlated with symptoms of restricted and repetitive behaviours in autistic children. An association between Central CC volume and parental ratings of autistic mannerisms and motor skills was also found across participants, mostly driven by the non-autistic group. Conclusion These findings expand the current knowledge about the neural mechanisms underlying autism, suggesting that the reduced connectivity through the CC might have implications for both core autistic features and motor skills. En ligne : https://doi.org/10.1016/j.reia.2025.202626 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559

Understanding the link between parental stress and child autism spectrum disorder symptoms: Insights from Vietnam / Duong Thuy KHUU ; Thi Anh Nguyet NGUYEN ; Thi Phuong NGUYEN in Research in Autism, 125 (July 2025)  

Public ISBD [article]  inResearch in Autism > 125 (July 2025) . - p.202627 Titre : Understanding the link between parental stress and child autism spectrum disorder symptoms: Insights from Vietnam Type de document : Texte imprimé et/ou numérique Auteurs : Duong Thuy KHUU, Auteur ; Thi Anh Nguyet NGUYEN, Auteur ; Thi Phuong NGUYEN, Auteur Article en page(s) : p.202627 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder  Parental Stress  Child Characteristics  Social Interaction  Communication Problems  Behavioural Issues  Support Interventions  Mixed-Method Study Index. décimale : PER Périodiques Résumé : Background Parenting a child with autism spectrum disorder (ASD) is commonly linked with significant levels of stress. This study examines the prevalence of parental stress and its contributing factors, with a focus on the specific characteristics of autistic children in Vietnam, a country experiencing rapid economic development and social transformation. Methods This mixed-methods study involved 209 parents of autistic children in Hanoi, Vietnam. Quantitative data were gathered using self-reported questionnaires that assessed parental stress levels and child-specific features such as social interaction, communication, and behavioural difficulties. Additionally, qualitative data were collected through in-depth interviews with ten parents to provide a more nuanced understanding of their experiences and challenges. Results Over 50 % of parents reported feeling stress at a 'quite frequent' level or higher, with an average composite stress score of 2.60 out of 4, indicating significant stress. Physical symptoms (such as headaches and exhaustion) and cognitive stress indicators (such as worrisome thoughts and fears) were among the most common stress manifestations. There was a clear link discovered between parental stress and child-specific ASD-related issues, especially difficulties in social interaction and communication. Conclusion Parents of autistic children face substantial stress, which is closely linked to their children's specific social and communication challenges. Therefore, interventions to improve social skills, communication, and behavioural management in autistic children are essential. Additionally, providing parents with targeted support and resources for coping with such challenges can help minimise stress. Future research should aim to include more diverse populations and explore the long-term impacts of these stressors on parental well-being. En ligne : https://doi.org/10.1016/j.reia.2025.202627 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] Understanding the link between parental stress and child autism spectrum disorder symptoms: Insights from Vietnam [Texte imprimé et/ou numérique] / Duong Thuy KHUU, Auteur ; Thi Anh Nguyet NGUYEN, Auteur ; Thi Phuong NGUYEN, Auteur . - p.202627. Langues : Anglais (eng) in Research in Autism > 125 (July 2025) . - p.202627 Mots-clés : Autism Spectrum Disorder  Parental Stress  Child Characteristics  Social Interaction  Communication Problems  Behavioural Issues  Support Interventions  Mixed-Method Study Index. décimale : PER Périodiques Résumé : Background Parenting a child with autism spectrum disorder (ASD) is commonly linked with significant levels of stress. This study examines the prevalence of parental stress and its contributing factors, with a focus on the specific characteristics of autistic children in Vietnam, a country experiencing rapid economic development and social transformation. Methods This mixed-methods study involved 209 parents of autistic children in Hanoi, Vietnam. Quantitative data were gathered using self-reported questionnaires that assessed parental stress levels and child-specific features such as social interaction, communication, and behavioural difficulties. Additionally, qualitative data were collected through in-depth interviews with ten parents to provide a more nuanced understanding of their experiences and challenges. Results Over 50 % of parents reported feeling stress at a 'quite frequent' level or higher, with an average composite stress score of 2.60 out of 4, indicating significant stress. Physical symptoms (such as headaches and exhaustion) and cognitive stress indicators (such as worrisome thoughts and fears) were among the most common stress manifestations. There was a clear link discovered between parental stress and child-specific ASD-related issues, especially difficulties in social interaction and communication. Conclusion Parents of autistic children face substantial stress, which is closely linked to their children's specific social and communication challenges. Therefore, interventions to improve social skills, communication, and behavioural management in autistic children are essential. Additionally, providing parents with targeted support and resources for coping with such challenges can help minimise stress. Future research should aim to include more diverse populations and explore the long-term impacts of these stressors on parental well-being. En ligne : https://doi.org/10.1016/j.reia.2025.202627 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559