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Primary Care Provider and Child Characteristics Associated with Age of Diagnosis of Autism Spectrum Disorder: A Population-Based Cohort Study / Ayesha SIDDIQUA in Journal of Autism and Developmental Disorders, 52-7 (July 2022)
[article]
Titre : Primary Care Provider and Child Characteristics Associated with Age of Diagnosis of Autism Spectrum Disorder: A Population-Based Cohort Study Type de document : Texte imprimé et/ou numérique Auteurs : Ayesha SIDDIQUA, Auteur ; Magdalena JANUS, Auteur ; Ronit MESTERMAN, Auteur ; Eric DUKU, Auteur ; Kathy GEORGIADES, Auteur ; Farah SAXENA, Auteur ; Haoyu ZHAO, Auteur ; Natasha R. SAUNDERS, Auteur Article en page(s) : p.2896-2910 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis/epidemiology Child Cohort Studies Family Humans Ontario/epidemiology Primary Health Care Autism spectrum disorder Developmental disabilities Diagnosis Early development instrument Kindergarten Paediatricians Primary care Index. décimale : PER Périodiques Résumé : In a cohort of kindergarten children in Ontario, Canada with Autism Spectrum Disorder (ASD) (n=1522), we tested the association of age at ASD diagnosis and characteristics of (1) the child's primary care provider and, (2) the child using health administrative databases. We tested the association of primary care practice model and time from developmental delay identification to age at ASD diagnosis. Older age of diagnosis was associated with provider foreign training (vs. domestic) (adjusted Hazard Ratio [aHR] 1.17, 95% CI 1.03, 1.33) but not sex, care model, and years of practice. After developmental delay identification, children with paediatricians had longer time to diagnosis than children with providers in care models (aHR 0.68, 95% CI 0.54, 0.86). Findings can be used to inform primary care provider ASD training. En ligne : http://dx.doi.org/10.1007/s10803-021-05165-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477
in Journal of Autism and Developmental Disorders > 52-7 (July 2022) . - p.2896-2910[article] Primary Care Provider and Child Characteristics Associated with Age of Diagnosis of Autism Spectrum Disorder: A Population-Based Cohort Study [Texte imprimé et/ou numérique] / Ayesha SIDDIQUA, Auteur ; Magdalena JANUS, Auteur ; Ronit MESTERMAN, Auteur ; Eric DUKU, Auteur ; Kathy GEORGIADES, Auteur ; Farah SAXENA, Auteur ; Haoyu ZHAO, Auteur ; Natasha R. SAUNDERS, Auteur . - p.2896-2910.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 52-7 (July 2022) . - p.2896-2910
Mots-clés : Autism Spectrum Disorder/diagnosis/epidemiology Child Cohort Studies Family Humans Ontario/epidemiology Primary Health Care Autism spectrum disorder Developmental disabilities Diagnosis Early development instrument Kindergarten Paediatricians Primary care Index. décimale : PER Périodiques Résumé : In a cohort of kindergarten children in Ontario, Canada with Autism Spectrum Disorder (ASD) (n=1522), we tested the association of age at ASD diagnosis and characteristics of (1) the child's primary care provider and, (2) the child using health administrative databases. We tested the association of primary care practice model and time from developmental delay identification to age at ASD diagnosis. Older age of diagnosis was associated with provider foreign training (vs. domestic) (adjusted Hazard Ratio [aHR] 1.17, 95% CI 1.03, 1.33) but not sex, care model, and years of practice. After developmental delay identification, children with paediatricians had longer time to diagnosis than children with providers in care models (aHR 0.68, 95% CI 0.54, 0.86). Findings can be used to inform primary care provider ASD training. En ligne : http://dx.doi.org/10.1007/s10803-021-05165-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477 Sex differences in age of diagnosis of autism spectrum disorder: Preliminary evidence from Uganda / E. BONNEY in Autism Research, 15-1 (January 2022)
[article]
Titre : Sex differences in age of diagnosis of autism spectrum disorder: Preliminary evidence from Uganda Type de document : Texte imprimé et/ou numérique Auteurs : E. BONNEY, Auteur ; C. ABBO, Auteur ; C. OGARA, Auteur ; M. E. VILLALOBOS, Auteur ; J. T. ELISON, Auteur Article en page(s) : p.183-191 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis/epidemiology Blacks Child Child, Preschool Female Humans Male Retrospective Studies Sex Characteristics Uganda/epidemiology Africa Uganda age of diagnosis autism spectrum disorder sex differences Index. décimale : PER Périodiques Résumé : This study was performed to determine (a) the age at which autism spectrum disorder (ASD) is first diagnosed in Ugandan children receiving mental health services, (b) whether age at diagnosis varies by sex and clinical presentation, and (c) the average age of ASD diagnosis in children manifesting comorbid conditions. A retrospective chart review was performed and demographic as well as clinical data were collected from children with ASD diagnoses who attended two mental health clinics in Uganda between 2014 and 2019. Descriptive statistics such as percentages, means, and standard deviations were used to summarize the data. Independent t-test was also performed to determine differences in the mean age of diagnosis between males and females. Two hundred and thirty-seven (156 males, 81 females) children with ASD were identified. The average age of ASD diagnosis was (6.9?±?4.0)?years. A statistically significant difference in age of ASD diagnosis was found between males and females (t = -2.106, p = 0.036), such that on average females received a diagnosis at least 1?year later than males. Of the 237 participants, 53.6% were identified with ASD only, 16.0% had ASD and ADHD, 10.5% were diagnosed with ASD and epilepsy, and 7.2% had a diagnosis of complex ASD. The results confirm delays in access to ASD diagnosis and suggest that females are more likely to receive a ASD diagnosis later than males within the Ugandan context. ASD awareness should be intensified to improve public or professional knowledge about ASD to enhance early identification in Uganda. En ligne : http://dx.doi.org/10.1002/aur.2645 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450
in Autism Research > 15-1 (January 2022) . - p.183-191[article] Sex differences in age of diagnosis of autism spectrum disorder: Preliminary evidence from Uganda [Texte imprimé et/ou numérique] / E. BONNEY, Auteur ; C. ABBO, Auteur ; C. OGARA, Auteur ; M. E. VILLALOBOS, Auteur ; J. T. ELISON, Auteur . - p.183-191.
Langues : Anglais (eng)
in Autism Research > 15-1 (January 2022) . - p.183-191
Mots-clés : Autism Spectrum Disorder/diagnosis/epidemiology Blacks Child Child, Preschool Female Humans Male Retrospective Studies Sex Characteristics Uganda/epidemiology Africa Uganda age of diagnosis autism spectrum disorder sex differences Index. décimale : PER Périodiques Résumé : This study was performed to determine (a) the age at which autism spectrum disorder (ASD) is first diagnosed in Ugandan children receiving mental health services, (b) whether age at diagnosis varies by sex and clinical presentation, and (c) the average age of ASD diagnosis in children manifesting comorbid conditions. A retrospective chart review was performed and demographic as well as clinical data were collected from children with ASD diagnoses who attended two mental health clinics in Uganda between 2014 and 2019. Descriptive statistics such as percentages, means, and standard deviations were used to summarize the data. Independent t-test was also performed to determine differences in the mean age of diagnosis between males and females. Two hundred and thirty-seven (156 males, 81 females) children with ASD were identified. The average age of ASD diagnosis was (6.9?±?4.0)?years. A statistically significant difference in age of ASD diagnosis was found between males and females (t = -2.106, p = 0.036), such that on average females received a diagnosis at least 1?year later than males. Of the 237 participants, 53.6% were identified with ASD only, 16.0% had ASD and ADHD, 10.5% were diagnosed with ASD and epilepsy, and 7.2% had a diagnosis of complex ASD. The results confirm delays in access to ASD diagnosis and suggest that females are more likely to receive a ASD diagnosis later than males within the Ugandan context. ASD awareness should be intensified to improve public or professional knowledge about ASD to enhance early identification in Uganda. En ligne : http://dx.doi.org/10.1002/aur.2645 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 2D:4D Ratio and Autism Spectrum Disorder in Brunei Darussalam / S. H. F. LEE in Journal of Autism and Developmental Disorders, 51-12 (December 2021)
[article]
Titre : 2D:4D Ratio and Autism Spectrum Disorder in Brunei Darussalam Type de document : Texte imprimé et/ou numérique Auteurs : S. H. F. LEE, Auteur ; S. A. AZIZ, Auteur ; M. HAMID, Auteur ; Y. C. LIM, Auteur ; D. KOH, Auteur ; L. L. CHAW, Auteur Article en page(s) : p.4577-4586 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis/epidemiology Brunei Case-Control Studies Child Child, Preschool Female Fingers Hand Humans Male Sex Characteristics 2D:4D ratio 2D:4D ratio symmetry Androgens Autism spectrum disorders (ASD) Brunei Darussalam Digit ratio Extreme male brain (EMB) Hormones Testosterone this manuscript. Index. décimale : PER Périodiques Résumé : BACKGROUND: Despite the global increase in the prevalence of autism spectrum disorders (ASD), relevant research studies are lacking in Brunei Darussalam. Various studies have shown a significant association between a lowered 2D:4D ratio (ratio of second digit/index finger to the fourth digit/ring finger) and ASD, making it one of the potential phenotypic biomarkers for early detection of autism, which is important for early intervention and management. OBJECTIVE: The objective of this study is to explore the association between 2D:4D ratio and ASD in Brunei Darussalam, as a potential tool to complement early ASD diagnosis. METHODS: We conducted a case-control study comprising 28 ASD and 62 typically developing (TD) children in the case and control group, respectively (age range: 3-11 years old; median age: 6 years old). Median 2D:4D ratios were measured, compared and analysed between the two groups. Logistic regression models were used to explore potential associations between the median 2D:4D ratio and ASD in respective gender, for both left and right hands, independently. RESULTS: Our study shows that the median 2D:4D ratio of left hand in ASD males is significantly lower than those in TD males, after adjusting for ethnicity and age [Odds Ratio (OR)?=?0.57 (95% Confidence Interval (CI): 0.31-0.96); p?=?0.044]. For females, there is no association of ASD with the median left hand 2D:4D ratio [OR?=?3.09 (95% CI: 0.98-19.86); p?=?0.144] or the median right hand 2D:4D ratio [OR?=?1.23 (95% CI: 0.42-3.88); p?=?0.702]. Our study also shows a significant positive correlation and/or a reduced asymmetry between the average 2D:4D ratio of left hands and right hands in ASD males (Pearson's correlation (r)?=?0.48; 95% CI: 0.076-0.75, p?=?0.023). CONCLUSIONS: There is significant association between a lowered median 2D:4D ratio of the left hand (in males only) and ASD diagnosis. Once validated in a larger sample size, a lowered median 2D:4D ratio on the left hand may be a potential tool to complement ASD diagnosis for males in our study population. There is no association between the median 2D:4D ratio (left or right hands) and ASD in females, which could be due to the small female sample size and/or the possibility of different aetiology for ASD in females. Reduced asymmetry between the average 2D:4D ratio of left and right hands observed in ASD males only (not in ASD females) also suggests the importance of considering gender-specific biomarkers for ASD diagnosis. En ligne : http://dx.doi.org/10.1007/s10803-021-04899-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454
in Journal of Autism and Developmental Disorders > 51-12 (December 2021) . - p.4577-4586[article] 2D:4D Ratio and Autism Spectrum Disorder in Brunei Darussalam [Texte imprimé et/ou numérique] / S. H. F. LEE, Auteur ; S. A. AZIZ, Auteur ; M. HAMID, Auteur ; Y. C. LIM, Auteur ; D. KOH, Auteur ; L. L. CHAW, Auteur . - p.4577-4586.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 51-12 (December 2021) . - p.4577-4586
Mots-clés : Autism Spectrum Disorder/diagnosis/epidemiology Brunei Case-Control Studies Child Child, Preschool Female Fingers Hand Humans Male Sex Characteristics 2D:4D ratio 2D:4D ratio symmetry Androgens Autism spectrum disorders (ASD) Brunei Darussalam Digit ratio Extreme male brain (EMB) Hormones Testosterone this manuscript. Index. décimale : PER Périodiques Résumé : BACKGROUND: Despite the global increase in the prevalence of autism spectrum disorders (ASD), relevant research studies are lacking in Brunei Darussalam. Various studies have shown a significant association between a lowered 2D:4D ratio (ratio of second digit/index finger to the fourth digit/ring finger) and ASD, making it one of the potential phenotypic biomarkers for early detection of autism, which is important for early intervention and management. OBJECTIVE: The objective of this study is to explore the association between 2D:4D ratio and ASD in Brunei Darussalam, as a potential tool to complement early ASD diagnosis. METHODS: We conducted a case-control study comprising 28 ASD and 62 typically developing (TD) children in the case and control group, respectively (age range: 3-11 years old; median age: 6 years old). Median 2D:4D ratios were measured, compared and analysed between the two groups. Logistic regression models were used to explore potential associations between the median 2D:4D ratio and ASD in respective gender, for both left and right hands, independently. RESULTS: Our study shows that the median 2D:4D ratio of left hand in ASD males is significantly lower than those in TD males, after adjusting for ethnicity and age [Odds Ratio (OR)?=?0.57 (95% Confidence Interval (CI): 0.31-0.96); p?=?0.044]. For females, there is no association of ASD with the median left hand 2D:4D ratio [OR?=?3.09 (95% CI: 0.98-19.86); p?=?0.144] or the median right hand 2D:4D ratio [OR?=?1.23 (95% CI: 0.42-3.88); p?=?0.702]. Our study also shows a significant positive correlation and/or a reduced asymmetry between the average 2D:4D ratio of left hands and right hands in ASD males (Pearson's correlation (r)?=?0.48; 95% CI: 0.076-0.75, p?=?0.023). CONCLUSIONS: There is significant association between a lowered median 2D:4D ratio of the left hand (in males only) and ASD diagnosis. Once validated in a larger sample size, a lowered median 2D:4D ratio on the left hand may be a potential tool to complement ASD diagnosis for males in our study population. There is no association between the median 2D:4D ratio (left or right hands) and ASD in females, which could be due to the small female sample size and/or the possibility of different aetiology for ASD in females. Reduced asymmetry between the average 2D:4D ratio of left and right hands observed in ASD males only (not in ASD females) also suggests the importance of considering gender-specific biomarkers for ASD diagnosis. En ligne : http://dx.doi.org/10.1007/s10803-021-04899-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454 Autism Spectrum Disorder and Clinical High Risk for Psychosis: A Systematic Review and Meta-analysis / Julio VAQUERIZO-SERRANO in Journal of Autism and Developmental Disorders, 52-4 (April 2022)
[article]
Titre : Autism Spectrum Disorder and Clinical High Risk for Psychosis: A Systematic Review and Meta-analysis Type de document : Texte imprimé et/ou numérique Auteurs : Julio VAQUERIZO-SERRANO, Auteur ; Gonzalo SALAZAR DE PABLO, Auteur ; Jatinder SINGH, Auteur ; Paramala SANTOSH, Auteur Article en page(s) : p.1568-1586 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis/epidemiology Child Humans Psychotic Disorders/diagnosis Syndrome Autism spectrum disorders Clinical high-risk for psychosis Meta-analysis Prodromal psychosis Psychosis Systematic review Index. décimale : PER Périodiques Résumé : Psychotic experiences can occur in autism spectrum disorders (ASD). Some of the ASD individuals with these experiences may fulfil Clinical High-Risk for Psychosis (CHR-P) criteria. A systematic literature search was performed to review the information on ASD and CHR-P. A meta-analysis of the proportion of CHR-P in ASD was conducted. The systematic review included 13 studies. The mean age of ASD individuals across the included studies was 11.09 years. The Attenuated Psychosis Syndrome subgroup was the most frequently reported. Four studies were meta-analysed, showing that 11.6% of CHR-P individuals have an ASD diagnosis. Symptoms of prodromal psychosis may be present in individuals with ASD. The transition from CHR-P to psychosis is not affected by ASD. En ligne : http://dx.doi.org/10.1007/s10803-021-05046-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475
in Journal of Autism and Developmental Disorders > 52-4 (April 2022) . - p.1568-1586[article] Autism Spectrum Disorder and Clinical High Risk for Psychosis: A Systematic Review and Meta-analysis [Texte imprimé et/ou numérique] / Julio VAQUERIZO-SERRANO, Auteur ; Gonzalo SALAZAR DE PABLO, Auteur ; Jatinder SINGH, Auteur ; Paramala SANTOSH, Auteur . - p.1568-1586.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 52-4 (April 2022) . - p.1568-1586
Mots-clés : Autism Spectrum Disorder/diagnosis/epidemiology Child Humans Psychotic Disorders/diagnosis Syndrome Autism spectrum disorders Clinical high-risk for psychosis Meta-analysis Prodromal psychosis Psychosis Systematic review Index. décimale : PER Périodiques Résumé : Psychotic experiences can occur in autism spectrum disorders (ASD). Some of the ASD individuals with these experiences may fulfil Clinical High-Risk for Psychosis (CHR-P) criteria. A systematic literature search was performed to review the information on ASD and CHR-P. A meta-analysis of the proportion of CHR-P in ASD was conducted. The systematic review included 13 studies. The mean age of ASD individuals across the included studies was 11.09 years. The Attenuated Psychosis Syndrome subgroup was the most frequently reported. Four studies were meta-analysed, showing that 11.6% of CHR-P individuals have an ASD diagnosis. Symptoms of prodromal psychosis may be present in individuals with ASD. The transition from CHR-P to psychosis is not affected by ASD. En ligne : http://dx.doi.org/10.1007/s10803-021-05046-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475 Characterizing Available Tools for Synchronous Virtual Assessment of Toddlers with Suspected Autism Spectrum Disorder: A Brief Report / Natalie I. BERGER in Journal of Autism and Developmental Disorders, 52-1 (January 2022)
[article]
Titre : Characterizing Available Tools for Synchronous Virtual Assessment of Toddlers with Suspected Autism Spectrum Disorder: A Brief Report Type de document : Texte imprimé et/ou numérique Auteurs : Natalie I. BERGER, Auteur ; Allison L. WAINER, Auteur ; J. KUHN, Auteur ; Karen E. BEARSS, Auteur ; S. ATTAR, Auteur ; Alice S. CARTER, Auteur ; L. V. IBANEZ, Auteur ; Brooke R. INGERSOLL, Auteur ; H. NEIDERMAN, Auteur ; S. SCOTT, Auteur ; W. L. STONE, Auteur Article en page(s) : p.423-434 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis/epidemiology Covid-19 Caregivers Child, Preschool Humans Pandemics SARS-CoV-2 Assessment Autism Autism spectrum disorder (ASD) Diagnosis Remote assessment Telehealth Toddlers Virtual Index. décimale : PER Périodiques Résumé : The COVID-19 pandemic, and associated social distancing mandates, has placed significant limitations on in-person health services, requiring creative solutions for supporting clinicians engaged in the diagnosis of autism spectrum disorder (ASD). This report describes the five virtual instruments available at the time of manuscript development for use by experienced clinicians making diagnostic determinations of ASD for toddlers across the 12- to 36-months age range. We focus on synchronous virtual assessments in which clinicians guide the child's caregiver through a range of assessment activities and observe spontaneous and elicited behaviors. Assessments are compared on dimensions of targeted behavioral domains, specific activities and presses employed, scoring approaches, and other key logistical considerations to guide instrument selection for use in varied clinical and research contexts. En ligne : http://dx.doi.org/10.1007/s10803-021-04911-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455
in Journal of Autism and Developmental Disorders > 52-1 (January 2022) . - p.423-434[article] Characterizing Available Tools for Synchronous Virtual Assessment of Toddlers with Suspected Autism Spectrum Disorder: A Brief Report [Texte imprimé et/ou numérique] / Natalie I. BERGER, Auteur ; Allison L. WAINER, Auteur ; J. KUHN, Auteur ; Karen E. BEARSS, Auteur ; S. ATTAR, Auteur ; Alice S. CARTER, Auteur ; L. V. IBANEZ, Auteur ; Brooke R. INGERSOLL, Auteur ; H. NEIDERMAN, Auteur ; S. SCOTT, Auteur ; W. L. STONE, Auteur . - p.423-434.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 52-1 (January 2022) . - p.423-434
Mots-clés : Autism Spectrum Disorder/diagnosis/epidemiology Covid-19 Caregivers Child, Preschool Humans Pandemics SARS-CoV-2 Assessment Autism Autism spectrum disorder (ASD) Diagnosis Remote assessment Telehealth Toddlers Virtual Index. décimale : PER Périodiques Résumé : The COVID-19 pandemic, and associated social distancing mandates, has placed significant limitations on in-person health services, requiring creative solutions for supporting clinicians engaged in the diagnosis of autism spectrum disorder (ASD). This report describes the five virtual instruments available at the time of manuscript development for use by experienced clinicians making diagnostic determinations of ASD for toddlers across the 12- to 36-months age range. We focus on synchronous virtual assessments in which clinicians guide the child's caregiver through a range of assessment activities and observe spontaneous and elicited behaviors. Assessments are compared on dimensions of targeted behavioral domains, specific activities and presses employed, scoring approaches, and other key logistical considerations to guide instrument selection for use in varied clinical and research contexts. En ligne : http://dx.doi.org/10.1007/s10803-021-04911-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455 Clinician Perspectives on Telehealth Assessment of Autism Spectrum Disorder During the COVID-19 Pandemic / Elizabeth M. KRYSZAK in Journal of Autism and Developmental Disorders, 52-12 (December 2022)
PermalinkA Distinct Three-Factor Structure of Restricted and Repetitive Behaviors in an Epidemiologically Sound Sample of Preschool-Age Children with Autism Spectrum Disorder / L. HIRUMA in Journal of Autism and Developmental Disorders, 51-10 (October 2021)
PermalinkIdentifying Patient Characteristics to Understand Which Children May Receive Diagnostic Clarity in a Virtual Autism Spectrum Disorder Evaluation / Randi A. PHELPS in Journal of Autism and Developmental Disorders, 52-12 (December 2022)
PermalinkPerinatal and Obstetric Predictors for Autism Spectrum Disorder / A. PERALES-MARÍN in Journal of Autism and Developmental Disorders, 51-11 (November 2021)
PermalinkReferral, Assessment and Use of Screening Measures Related to Autism Spectrum Disorder at a Tertiary Hospital Setting / C. BERNIE in Journal of Autism and Developmental Disorders, 51-8 (August 2021)
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