Dépouillements

Why We Need to Study Assisted Methods to Teach Typing to Nonspeaking Autistic People / Vikram K. JASWAL in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70176 Titre : Why We Need to Study Assisted Methods to Teach Typing to Nonspeaking Autistic People Type de document : texte imprimé Auteurs : Vikram K. JASWAL, Auteur ; Barry M. PRIZANT, Auteur ; Morgan D. BARENSE, Auteur ; Kristie PATTEN, Auteur ; Gary STOBBE, Auteur Article en page(s) : p.e70176 Langues : Anglais (eng) Mots-clés : assisted typing  autism  communication  nonspeaking Index. décimale : PER Périodiques Résumé : ABSTRACT At least one third of autistic people have limited or no speech. Most nonspeaking autistic people are never provided alternatives that would enable the full range of expression that speech allows, significantly limiting their access to educational, social, and employment opportunities. In this commentary, we argue that assisted methods to teach nonspeaking autistic people to type?long dismissed because the assistant could influence the text they produce during training?warrant fresh study. Although these teaching methods developed in practice rather than research, the practice (including the range of support the assistant provides in the motor, sensory, and attentional domains) is aligned with contemporary research about nonspeaking autistic people's strengths and challenges. We suggest that past research showing that influence can occur during training has been over-interpreted to mean that influence always occurs and that nonspeaking autistic people instructed using assisted methods never learn to type independently. In fact, other research shows that influence does not always occur, and there are independent typers who attribute their skill to the range of assistance they received during training. We believe it is time to revisit assisted methods to teach typing in order to understand their potential, as well as their limits, including how successful learners became independent and for whom these methods would be a good match. These efforts have the potential to result in greater access to effective communication and better quality of life for more nonspeaking autistic people. En ligne : https://doi.org/10.1002/aur.70176 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Why We Need to Study Assisted Methods to Teach Typing to Nonspeaking Autistic People [texte imprimé] / Vikram K. JASWAL, Auteur ; Barry M. PRIZANT, Auteur ; Morgan D. BARENSE, Auteur ; Kristie PATTEN, Auteur ; Gary STOBBE, Auteur . - p.e70176. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70176 Mots-clés : assisted typing  autism  communication  nonspeaking Index. décimale : PER Périodiques Résumé : ABSTRACT At least one third of autistic people have limited or no speech. Most nonspeaking autistic people are never provided alternatives that would enable the full range of expression that speech allows, significantly limiting their access to educational, social, and employment opportunities. In this commentary, we argue that assisted methods to teach nonspeaking autistic people to type?long dismissed because the assistant could influence the text they produce during training?warrant fresh study. Although these teaching methods developed in practice rather than research, the practice (including the range of support the assistant provides in the motor, sensory, and attentional domains) is aligned with contemporary research about nonspeaking autistic people's strengths and challenges. We suggest that past research showing that influence can occur during training has been over-interpreted to mean that influence always occurs and that nonspeaking autistic people instructed using assisted methods never learn to type independently. In fact, other research shows that influence does not always occur, and there are independent typers who attribute their skill to the range of assistance they received during training. We believe it is time to revisit assisted methods to teach typing in order to understand their potential, as well as their limits, including how successful learners became independent and for whom these methods would be a good match. These efforts have the potential to result in greater access to effective communication and better quality of life for more nonspeaking autistic people. En ligne : https://doi.org/10.1002/aur.70176 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Labor Epidural Analgesia and Autism Spectrum Disorder in Offspring: A Population-Based Case–Control Study / Taniqua T. INGOL in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70210 Titre : Labor Epidural Analgesia and Autism Spectrum Disorder in Offspring: A Population-Based Case–Control Study Type de document : texte imprimé Auteurs : Taniqua T. INGOL, Auteur ; Jessie K. EDWARDS, Auteur ; Mollie E. WOOD, Auteur ; Chantel L. MARTIN, Auteur ; Gabriel S. DICHTER, Auteur ; Keith FELDMAN, Auteur ; Alan C. KINLAW, Auteur ; Julie L. DANIELS, Auteur Article en page(s) : p.e70210 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  epidemiology  labor and delivery  labor epidural analgesia  pregnancy risk factors Index. décimale : PER Périodiques Résumé : ABSTRACT While the immediate benefits of labor epidural analgesia (LEA) are well established, recent studies have raised concerns about possible associations with autism spectrum disorder (ASD). Therefore, we examined the association between LEA and ASD in offspring. We analyzed data from mother?child dyads enrolled in the Study to Explore Early Development (2007?2020), a US multisite case?control study. Receipt of LEA during childbirth and other covariate information was ascertained from a combination of maternal self-report, medical record abstraction, and the birth certificate. ASD classification was determined by trained psychologists using the Autism Diagnostic Observation Schedule and Autism Diagnostic Interview-Revised. We used logistic regression to estimate the odds ratio (OR) for the association between LEA and ASD in offspring. Models were adjusted for demographic and pregnancy factors. Sensitivity analyses restricted to term deliveries, singleton pregnancies, and vaginal births were conducted. Our sample included 2039 ASD cases and 3171 controls. The prevalence of LEA use was similar among cases and controls (66% and 67%, respectively). The crude OR for the association between LEA and ASD was 0.97 (95% CI: 0.85, 1.10), and the adjusted OR was 1.02 (95% CI: 0.89, 1.17). Findings from sensitivity analyses were generally consistent with the primary results. Subtle associations emerged when the analysis was restricted to vaginal deliveries; however, they attenuated after additional adjustment for fetal distress, induced or augmented labor, and prolonged labor. Our findings do not support an association between LEA and ASD in offspring. En ligne : https://doi.org/10.1002/aur.70210 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Labor Epidural Analgesia and Autism Spectrum Disorder in Offspring: A Population-Based Case–Control Study [texte imprimé] / Taniqua T. INGOL, Auteur ; Jessie K. EDWARDS, Auteur ; Mollie E. WOOD, Auteur ; Chantel L. MARTIN, Auteur ; Gabriel S. DICHTER, Auteur ; Keith FELDMAN, Auteur ; Alan C. KINLAW, Auteur ; Julie L. DANIELS, Auteur . - p.e70210. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70210 Mots-clés : autism spectrum disorder  epidemiology  labor and delivery  labor epidural analgesia  pregnancy risk factors Index. décimale : PER Périodiques Résumé : ABSTRACT While the immediate benefits of labor epidural analgesia (LEA) are well established, recent studies have raised concerns about possible associations with autism spectrum disorder (ASD). Therefore, we examined the association between LEA and ASD in offspring. We analyzed data from mother?child dyads enrolled in the Study to Explore Early Development (2007?2020), a US multisite case?control study. Receipt of LEA during childbirth and other covariate information was ascertained from a combination of maternal self-report, medical record abstraction, and the birth certificate. ASD classification was determined by trained psychologists using the Autism Diagnostic Observation Schedule and Autism Diagnostic Interview-Revised. We used logistic regression to estimate the odds ratio (OR) for the association between LEA and ASD in offspring. Models were adjusted for demographic and pregnancy factors. Sensitivity analyses restricted to term deliveries, singleton pregnancies, and vaginal births were conducted. Our sample included 2039 ASD cases and 3171 controls. The prevalence of LEA use was similar among cases and controls (66% and 67%, respectively). The crude OR for the association between LEA and ASD was 0.97 (95% CI: 0.85, 1.10), and the adjusted OR was 1.02 (95% CI: 0.89, 1.17). Findings from sensitivity analyses were generally consistent with the primary results. Subtle associations emerged when the analysis was restricted to vaginal deliveries; however, they attenuated after additional adjustment for fetal distress, induced or augmented labor, and prolonged labor. Our findings do not support an association between LEA and ASD in offspring. En ligne : https://doi.org/10.1002/aur.70210 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Compulsion Profile Differences Indicate Distinct Functional Mechanisms in Autistic and Non-Autistic University Students / Gil ZUKERMAN in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70215 Titre : Compulsion Profile Differences Indicate Distinct Functional Mechanisms in Autistic and Non-Autistic University Students Type de document : texte imprimé Auteurs : Gil ZUKERMAN, Auteur ; Ester BEN–ITZCHAK, Auteur Article en page(s) : p.e70215 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : ABSTRACT Autistic individuals often exhibit high rates of obsessive-compulsive symptoms (OCS), yet traditional cognitive-behavioral therapy (CBT), especially exposure and response prevention (ERP), tends to be less effective for them. This may be due to differences in the function of compulsive behaviors: while OCD-related compulsions are typically ego-dystonic and aimed at reducing anxiety, autistic compulsions may be ego-syntonic, serving regulatory or sensory modulation purposes. This study investigated whether compulsions in autism are more aligned with regulation and sensory modulation than with anxiety reduction. Participants included 39 autistic university students, 25 non-autistic students with high OCS, and 25 non-autistic students with low OCS. A factor analysis of seven binary items from the Yale?Brown Obsessive-Compulsive Scale (Y-BOCS-I) revealed two factors explaining 58% of the variance. The first factor showed high loadings for Repetition, Counting, and Hoarding compulsions, reflecting regulatory and sensory modulation processes. The second factor showed high loadings for checking and organizing compulsions that were previously associated with anxiety reduction. Chi-square analyses showed autistic students reported significantly more regulatory/sensory compulsions than low-OCS individuals. For anxiety-reduction compulsions, autistic students reported significantly fewer positive responses than both non-autistic groups. Trait and state anxiety correlated with OCS levels in non-autistic participants, but not in autistic individuals. These findings indicate that compulsions in autism may reflect distinct functional mechanisms compared to those in classical OCD. Specifically, the weaker association with anxiety or threat reduction suggests that ERP-based CBT, which targets anxiety-driven compulsions, may be less effective for autistic individuals. Broader implications for both diagnosis and therapeutic approaches are discussed. En ligne : https://doi.org/10.1002/aur.70215 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Compulsion Profile Differences Indicate Distinct Functional Mechanisms in Autistic and Non-Autistic University Students [texte imprimé] / Gil ZUKERMAN, Auteur ; Ester BEN–ITZCHAK, Auteur . - p.e70215. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70215 Index. décimale : PER Périodiques Résumé : ABSTRACT Autistic individuals often exhibit high rates of obsessive-compulsive symptoms (OCS), yet traditional cognitive-behavioral therapy (CBT), especially exposure and response prevention (ERP), tends to be less effective for them. This may be due to differences in the function of compulsive behaviors: while OCD-related compulsions are typically ego-dystonic and aimed at reducing anxiety, autistic compulsions may be ego-syntonic, serving regulatory or sensory modulation purposes. This study investigated whether compulsions in autism are more aligned with regulation and sensory modulation than with anxiety reduction. Participants included 39 autistic university students, 25 non-autistic students with high OCS, and 25 non-autistic students with low OCS. A factor analysis of seven binary items from the Yale?Brown Obsessive-Compulsive Scale (Y-BOCS-I) revealed two factors explaining 58% of the variance. The first factor showed high loadings for Repetition, Counting, and Hoarding compulsions, reflecting regulatory and sensory modulation processes. The second factor showed high loadings for checking and organizing compulsions that were previously associated with anxiety reduction. Chi-square analyses showed autistic students reported significantly more regulatory/sensory compulsions than low-OCS individuals. For anxiety-reduction compulsions, autistic students reported significantly fewer positive responses than both non-autistic groups. Trait and state anxiety correlated with OCS levels in non-autistic participants, but not in autistic individuals. These findings indicate that compulsions in autism may reflect distinct functional mechanisms compared to those in classical OCD. Specifically, the weaker association with anxiety or threat reduction suggests that ERP-based CBT, which targets anxiety-driven compulsions, may be less effective for autistic individuals. Broader implications for both diagnosis and therapeutic approaches are discussed. En ligne : https://doi.org/10.1002/aur.70215 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Vocabulary of Autistic Preschool Children With Limited Language: Alignment With Early Word Inventories / Eunji KONG in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70216 Titre : Vocabulary of Autistic Preschool Children With Limited Language: Alignment With Early Word Inventories Type de document : texte imprimé Auteurs : Eunji KONG, Auteur ; Yitong JIANG, Auteur ; Marina CRAIN, Auteur ; Wenjing BAO, Auteur ; Lynne LEVATO, Auteur ; Wendy SHIH, Auteur ; Connie KASARI, Auteur ; Stephanie SHIRE, Auteur Article en page(s) : p.e70216 Langues : Anglais (eng) Mots-clés : autism  child  language development  preschool  speech  vocabulary Index. décimale : PER Périodiques Résumé : ABSTRACT There is a critical need to understand the early vocabulary of young children with autism who have limited language, defined in this study as producing fewer than 20 different spontaneous and functional spoken or augmented words, to better inform educational targets and vocabulary selection for spoken as well as augmentative and alternative communication (AAC) interventions, particularly given the lack of evaluation tools designed for children with limited language. The spontaneous words and gestures produced by 66 preschoolers with autism (ages 3.5?5) during a natural language sample are compared with words in two early vocabulary tools including the MacArthur Communicative Development Inventories (MCDI) and a list of core words compiled from research studies of early AAC vocabulary. Participants' expressive words and gestures were coded from the transcripts of 20-min natural language samples. Forty-nine children (74.24%) used spoken words, gestures, or a combination of both, with six children (9.09%) communicating using a speech-generating device (SGD). Spoken words were primarily used for commenting, while gestures, especially pointing, were used for requesting. Although more than half of the unique words expressed by the children during the natural language sample overlapped with those in the MCDI, only 32% of unique words expressed by the children overlapped with Laubscher's and Light's core word lists, suggesting that young children with autism who have limited language may use more fringe words related to their personal interests or experiences. The study's limitations as well as implications for vocabulary selection for AAC systems and intervention goals are discussed. En ligne : https://doi.org/10.1002/aur.70216 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Vocabulary of Autistic Preschool Children With Limited Language: Alignment With Early Word Inventories [texte imprimé] / Eunji KONG, Auteur ; Yitong JIANG, Auteur ; Marina CRAIN, Auteur ; Wenjing BAO, Auteur ; Lynne LEVATO, Auteur ; Wendy SHIH, Auteur ; Connie KASARI, Auteur ; Stephanie SHIRE, Auteur . - p.e70216. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70216 Mots-clés : autism  child  language development  preschool  speech  vocabulary Index. décimale : PER Périodiques Résumé : ABSTRACT There is a critical need to understand the early vocabulary of young children with autism who have limited language, defined in this study as producing fewer than 20 different spontaneous and functional spoken or augmented words, to better inform educational targets and vocabulary selection for spoken as well as augmentative and alternative communication (AAC) interventions, particularly given the lack of evaluation tools designed for children with limited language. The spontaneous words and gestures produced by 66 preschoolers with autism (ages 3.5?5) during a natural language sample are compared with words in two early vocabulary tools including the MacArthur Communicative Development Inventories (MCDI) and a list of core words compiled from research studies of early AAC vocabulary. Participants' expressive words and gestures were coded from the transcripts of 20-min natural language samples. Forty-nine children (74.24%) used spoken words, gestures, or a combination of both, with six children (9.09%) communicating using a speech-generating device (SGD). Spoken words were primarily used for commenting, while gestures, especially pointing, were used for requesting. Although more than half of the unique words expressed by the children during the natural language sample overlapped with those in the MCDI, only 32% of unique words expressed by the children overlapped with Laubscher's and Light's core word lists, suggesting that young children with autism who have limited language may use more fringe words related to their personal interests or experiences. The study's limitations as well as implications for vocabulary selection for AAC systems and intervention goals are discussed. En ligne : https://doi.org/10.1002/aur.70216 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Parenting Stress and Stressful Life Events Among Caregivers of Toddler Siblings of Autistic and Non-Autistic Children / Jennifer E. MAGNUSON in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70217 Titre : Parenting Stress and Stressful Life Events Among Caregivers of Toddler Siblings of Autistic and Non-Autistic Children Type de document : texte imprimé Auteurs : Jennifer E. MAGNUSON, Auteur ; Lucy S. KING, Auteur ; Jacob I. FELDMAN, Auteur ; S. Madison CLARK, Auteur ; Grace PULLIAM, Auteur ; Kacie DUNHAM-CARR, Auteur ; Alexandra GOLDEN, Auteur ; Bahar Keçeli KAYSıLı, Auteur ; Kathryn L. HUMPHREYS, Auteur ; Tiffany G. WOYNAROSKI, Auteur Article en page(s) : p.e70217 Langues : Anglais (eng) Mots-clés : autism  caregiving  infant siblings  measurement  parent mental health  stress Index. décimale : PER Périodiques Résumé : ABSTRACT This study measured experiences of parenting stress and stressful life events in caregivers of families with a toddler who has either an autistic or non-autistic older sibling(s). Caregivers of toddlers (12?18?months old) with older autistic siblings (Sibs-autism; n?=?58) and toddlers with older non-autistic siblings (Sibs-NA; n?=?46) completed questionnaires assessing stress related to parenting their toddler and their exposure to stressful life events since their toddler's birth. We compared levels of parenting stress and stressful life events between caregivers of Sibs-autism and Sibs-NA and examined the association between these measures. Caregivers of Sibs-autism reported significantly higher levels of parenting stress and stressful life events relative to caregivers of Sibs-NA, with small to moderate effects. Parenting stress and stressful life events were moderately correlated. Across these groups of caregivers, parenting stress and stressful life events appear to be related, but partially distinct aspects of caregiver stress. These findings highlight the importance of assessing multiple aspects of stress to better understand how stress may influence both caregiver wellbeing and the development of children with autistic siblings. En ligne : https://doi.org/10.1002/aur.70217 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Parenting Stress and Stressful Life Events Among Caregivers of Toddler Siblings of Autistic and Non-Autistic Children [texte imprimé] / Jennifer E. MAGNUSON, Auteur ; Lucy S. KING, Auteur ; Jacob I. FELDMAN, Auteur ; S. Madison CLARK, Auteur ; Grace PULLIAM, Auteur ; Kacie DUNHAM-CARR, Auteur ; Alexandra GOLDEN, Auteur ; Bahar Keçeli KAYSıLı, Auteur ; Kathryn L. HUMPHREYS, Auteur ; Tiffany G. WOYNAROSKI, Auteur . - p.e70217. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70217 Mots-clés : autism  caregiving  infant siblings  measurement  parent mental health  stress Index. décimale : PER Périodiques Résumé : ABSTRACT This study measured experiences of parenting stress and stressful life events in caregivers of families with a toddler who has either an autistic or non-autistic older sibling(s). Caregivers of toddlers (12?18?months old) with older autistic siblings (Sibs-autism; n?=?58) and toddlers with older non-autistic siblings (Sibs-NA; n?=?46) completed questionnaires assessing stress related to parenting their toddler and their exposure to stressful life events since their toddler's birth. We compared levels of parenting stress and stressful life events between caregivers of Sibs-autism and Sibs-NA and examined the association between these measures. Caregivers of Sibs-autism reported significantly higher levels of parenting stress and stressful life events relative to caregivers of Sibs-NA, with small to moderate effects. Parenting stress and stressful life events were moderately correlated. Across these groups of caregivers, parenting stress and stressful life events appear to be related, but partially distinct aspects of caregiver stress. These findings highlight the importance of assessing multiple aspects of stress to better understand how stress may influence both caregiver wellbeing and the development of children with autistic siblings. En ligne : https://doi.org/10.1002/aur.70217 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Trajectories of Autism Symptoms and Overlapping Patterns in a Chinese Cohort From 18 to 36 Months / Feixia ZHANG in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70219 Titre : Trajectories of Autism Symptoms and Overlapping Patterns in a Chinese Cohort From 18 to 36 Months Type de document : texte imprimé Auteurs : Feixia ZHANG, Auteur ; YanTing XU, Auteur ; Linru LIU, Auteur ; Yu XING, Auteur ; Cong YOU, Auteur ; ShaoLi LV, Auteur ; Huishi HUANG, Auteur ; YuanYuan ZOU, Auteur ; Fengjing LIANG, Auteur ; QianYing YE, Auteur ; Yijie LI, Auteur ; ShiHuan WANG, Auteur ; Kaiyun CHEN, Auteur ; Hongzhu DENG, Auteur Article en page(s) : p.e70219 Langues : Anglais (eng) Mots-clés : autism  autism symptoms  broader autism phenotype  early life  overlap Index. décimale : PER Périodiques Résumé : ABSTRACT Several studies have examined trajectories of autism symptoms in autistic children and their siblings. However, less is known about developmental patterns across different neurodevelopmental conditions, as well as the clinical characteristics and early predictors among children with distinct diagnoses but overlapping trajectories. This study investigated trajectories of autism symptoms [ADOS-2 Calibrated Severity Score; Total CSS, social affect (SA) CSS, and restricted and repetitive behaviors (RRB) CSS] and their overlap across symptom domains in a Chinese cohort of 163 children aged 18?36?months, including autism, broader autism phenotype (BAP), developmental delay (DD), and typical development (TD). Latent class growth modeling identified three trajectories for Total CSS and SA CSS, and two for RRB CSS. Cross-domain analyses revealed overlapping CSS trajectories between 51 autistic children (Overlap-Autism) and 36 children with BAP (Overlap-BAP). Clinical comparisons between these two groups revealed distinct temporal profiles in CSS and ADI-R scores. Hierarchical logistic regression analyses indicated that female sex was a protective factor for Overlap-Autism (OR?=?0.20, p?=?0.009) relative to the Overlap-BAP group, whereas higher SA CSS at 18?months independently predicted Overlap-Autism (OR?=?1.61, p?=?0.003). These findings highlight the challenges of early diagnostic differentiation among children with autism-related traits and underscore the importance of comprehensive and longitudinal assessment. En ligne : https://doi.org/10.1002/aur.70219 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Trajectories of Autism Symptoms and Overlapping Patterns in a Chinese Cohort From 18 to 36 Months [texte imprimé] / Feixia ZHANG, Auteur ; YanTing XU, Auteur ; Linru LIU, Auteur ; Yu XING, Auteur ; Cong YOU, Auteur ; ShaoLi LV, Auteur ; Huishi HUANG, Auteur ; YuanYuan ZOU, Auteur ; Fengjing LIANG, Auteur ; QianYing YE, Auteur ; Yijie LI, Auteur ; ShiHuan WANG, Auteur ; Kaiyun CHEN, Auteur ; Hongzhu DENG, Auteur . - p.e70219. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70219 Mots-clés : autism  autism symptoms  broader autism phenotype  early life  overlap Index. décimale : PER Périodiques Résumé : ABSTRACT Several studies have examined trajectories of autism symptoms in autistic children and their siblings. However, less is known about developmental patterns across different neurodevelopmental conditions, as well as the clinical characteristics and early predictors among children with distinct diagnoses but overlapping trajectories. This study investigated trajectories of autism symptoms [ADOS-2 Calibrated Severity Score; Total CSS, social affect (SA) CSS, and restricted and repetitive behaviors (RRB) CSS] and their overlap across symptom domains in a Chinese cohort of 163 children aged 18?36?months, including autism, broader autism phenotype (BAP), developmental delay (DD), and typical development (TD). Latent class growth modeling identified three trajectories for Total CSS and SA CSS, and two for RRB CSS. Cross-domain analyses revealed overlapping CSS trajectories between 51 autistic children (Overlap-Autism) and 36 children with BAP (Overlap-BAP). Clinical comparisons between these two groups revealed distinct temporal profiles in CSS and ADI-R scores. Hierarchical logistic regression analyses indicated that female sex was a protective factor for Overlap-Autism (OR?=?0.20, p?=?0.009) relative to the Overlap-BAP group, whereas higher SA CSS at 18?months independently predicted Overlap-Autism (OR?=?1.61, p?=?0.003). These findings highlight the challenges of early diagnostic differentiation among children with autism-related traits and underscore the importance of comprehensive and longitudinal assessment. En ligne : https://doi.org/10.1002/aur.70219 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Adverse Childhood Experiences in Autistic and Neurotypical Girls / Jon EBERT in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70221 Titre : Adverse Childhood Experiences in Autistic and Neurotypical Girls Type de document : texte imprimé Auteurs : Jon EBERT, Auteur ; Rachael A. MUSCATELLO, Auteur ; Trey MCGONIGLE, Auteur ; Simon VANDEKAR, Auteur ; Blythe A. CORBETT, Auteur Article en page(s) : p.e70221 Langues : Anglais (eng) Mots-clés : ACE  adolescence  adverse childhood  autism  puberty  trauma Index. décimale : PER Périodiques Résumé : ABSTRACT Adverse childhood experiences (ACEs) are potentially traumatic, life-altering events that occur in childhood with long-term negative physical and/or mental health outcomes. Previous research, while limited and largely focused on males, suggests children with autism spectrum disorder (ASD) are at higher risk of experiencing ACEs than typically developing (TD) peers. The study aimed to enhance our understanding of ACEs by focusing on female participants comparing diagnostic (ASD, TD), developmental (age, puberty), and mental health (anxiety, depression) factors. Participants included 212 female children with ASD (N?=?112) or TD (N?=?100) between 6:0 to 12:11?years. Following diagnostic testing, the 10-item ACEs questionnaire was administered. Statistical analyses included Wilcoxon rank-sum tests, negative-binomial models, linear regression, and Spearman correlations. There was a significant group difference in the total number of ACEs such that autistic children had more parent-reported total adverse events (p?=?0.024). There were no significant diagnosis by age or puberty stage interactions (p?>?0.05). Depressive symptoms were significantly positively associated with autism diagnosis (p? En ligne : https://doi.org/10.1002/aur.70221 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Adverse Childhood Experiences in Autistic and Neurotypical Girls [texte imprimé] / Jon EBERT, Auteur ; Rachael A. MUSCATELLO, Auteur ; Trey MCGONIGLE, Auteur ; Simon VANDEKAR, Auteur ; Blythe A. CORBETT, Auteur . - p.e70221. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70221 Mots-clés : ACE  adolescence  adverse childhood  autism  puberty  trauma Index. décimale : PER Périodiques Résumé : ABSTRACT Adverse childhood experiences (ACEs) are potentially traumatic, life-altering events that occur in childhood with long-term negative physical and/or mental health outcomes. Previous research, while limited and largely focused on males, suggests children with autism spectrum disorder (ASD) are at higher risk of experiencing ACEs than typically developing (TD) peers. The study aimed to enhance our understanding of ACEs by focusing on female participants comparing diagnostic (ASD, TD), developmental (age, puberty), and mental health (anxiety, depression) factors. Participants included 212 female children with ASD (N?=?112) or TD (N?=?100) between 6:0 to 12:11?years. Following diagnostic testing, the 10-item ACEs questionnaire was administered. Statistical analyses included Wilcoxon rank-sum tests, negative-binomial models, linear regression, and Spearman correlations. There was a significant group difference in the total number of ACEs such that autistic children had more parent-reported total adverse events (p?=?0.024). There were no significant diagnosis by age or puberty stage interactions (p?>?0.05). Depressive symptoms were significantly positively associated with autism diagnosis (p? En ligne : https://doi.org/10.1002/aur.70221 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

REM Sleep Abnormalities in Children With Autism Spectrum Disorder / Jiasen MA in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70222 Titre : REM Sleep Abnormalities in Children With Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Jiasen MA, Auteur ; Junjun QIN, Auteur ; Hongfang JIANG, Auteur ; Yueping CHE, Auteur ; Haifeng LI, Auteur ; Daqing MA, Auteur ; Jinpiao ZHU, Auteur Article en page(s) : p.e70222 Langues : Anglais (eng) Mots-clés : autism spectrum disorder (ASD)  machine learning  rapid eye movement sleep (REM)  SHapley additive explanation (SHAP) Index. décimale : PER Périodiques Résumé : ABSTRACT Sleep disturbances are common in children with autism spectrum disorder (ASD). However, the sleep pattern changes including rapid eye movement (REM) sleep for ASD in pediatric populations remain unknown. Using polysomnography (PSG) data from the National Children's Hospital (NCH) Sleep Databank, we identified 193 children with ASD and matched them with 193 Non-ASD controls. We found children with ASD showed reduced REM sleep proportion (17.8%?±?6.4% vs. 19.1%?±?7.0%; p?=?0.049) and duration (71.5 [49.5?91.0] min vs. 81.5 [52.5?98.0] min; p?=?0.036), prolonged REM latency (134.5 [94.0?181.5] min vs. 116.0 [82.0?157.0] min; p?=?0.009), and increased 1st REM duration (13.0 [7.0?19.0] min vs. 10.5 [6.0?16.5] min; p?=?0.024) compared with Non-ASD peers. They also showed higher 1st REM proportion (18.8 [11.0?31.3] vs. 15.7 [8.3?25.4]; p?=?0.003), particularly in children aged 3?5?years and 6?8?years. Using these REM features, the XGBoost machine learning model was achieved to be the best predictive performance. SHAP analysis further showed that decreased REM sleep duration, increased 1st REM proportion or duration, and prolonged REM latency were discriminative features for children with ASD. These findings suggest that REM sleep abnormalities are common in young patients with ASD but its contribution to the disease's severity and/or development needs to be explored further. En ligne : https://doi.org/10.1002/aur.70222 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] REM Sleep Abnormalities in Children With Autism Spectrum Disorder [texte imprimé] / Jiasen MA, Auteur ; Junjun QIN, Auteur ; Hongfang JIANG, Auteur ; Yueping CHE, Auteur ; Haifeng LI, Auteur ; Daqing MA, Auteur ; Jinpiao ZHU, Auteur . - p.e70222. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70222 Mots-clés : autism spectrum disorder (ASD)  machine learning  rapid eye movement sleep (REM)  SHapley additive explanation (SHAP) Index. décimale : PER Périodiques Résumé : ABSTRACT Sleep disturbances are common in children with autism spectrum disorder (ASD). However, the sleep pattern changes including rapid eye movement (REM) sleep for ASD in pediatric populations remain unknown. Using polysomnography (PSG) data from the National Children's Hospital (NCH) Sleep Databank, we identified 193 children with ASD and matched them with 193 Non-ASD controls. We found children with ASD showed reduced REM sleep proportion (17.8%?±?6.4% vs. 19.1%?±?7.0%; p?=?0.049) and duration (71.5 [49.5?91.0] min vs. 81.5 [52.5?98.0] min; p?=?0.036), prolonged REM latency (134.5 [94.0?181.5] min vs. 116.0 [82.0?157.0] min; p?=?0.009), and increased 1st REM duration (13.0 [7.0?19.0] min vs. 10.5 [6.0?16.5] min; p?=?0.024) compared with Non-ASD peers. They also showed higher 1st REM proportion (18.8 [11.0?31.3] vs. 15.7 [8.3?25.4]; p?=?0.003), particularly in children aged 3?5?years and 6?8?years. Using these REM features, the XGBoost machine learning model was achieved to be the best predictive performance. SHAP analysis further showed that decreased REM sleep duration, increased 1st REM proportion or duration, and prolonged REM latency were discriminative features for children with ASD. These findings suggest that REM sleep abnormalities are common in young patients with ASD but its contribution to the disease's severity and/or development needs to be explored further. En ligne : https://doi.org/10.1002/aur.70222 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Content Analysis of Responses From an INSAR Special Interest Group (SIG): Indigenous Perspectives on Autism / Grant BRUNO in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70224 Titre : Content Analysis of Responses From an INSAR Special Interest Group (SIG): Indigenous Perspectives on Autism Type de document : texte imprimé Auteurs : Grant BRUNO, Auteur ; Annie TANG, Auteur ; Troy Q. BOUCHER, Auteur ; Emily COOMBS, Auteur ; T. C. WAISMAN, Auteur ; Anne LINDBLOM, Auteur Article en page(s) : p.e70224 Langues : Anglais (eng) Mots-clés : autism  cultural supports  health outcomes  Indigenous  INSAR SIG  Special Interest Group Index. décimale : PER Périodiques Résumé : ABSTRACT Autism remains understudied and under-detected in Indigenous communities across the globe. This content analysis investigates key themes and future directions for Indigenous autism research, as discussed during a Special Interest Group at the 2025 International Society for Autism Research meeting in Seattle, United States. Discussions and perspectives were explored with shared knowledge from international participants who were service providers, Autistic self-advocates, academics, and other autism-related stakeholders. The emergent themes emphasized the need for autism research in Indigenous communities to utilize approaches that are decolonized, culturally informed, and strengths-based. The results highlighted the need for researchers to focus on building trust, fostering relationship-building, and encouraging collaborative research partnerships with communities, while addressing systemic limiting factors and integrating knowledge systems from Indigenous and Western models. There is also a desire for more Indigenous-led initiatives that allow non-Indigenous researchers to provide support. Overall, there is a clear interest in further Indigenous autism research initiatives, but further shifts are needed to ensure that efforts are community-led and strengths-based. En ligne : https://doi.org/10.1002/aur.70224 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Content Analysis of Responses From an INSAR Special Interest Group (SIG): Indigenous Perspectives on Autism [texte imprimé] / Grant BRUNO, Auteur ; Annie TANG, Auteur ; Troy Q. BOUCHER, Auteur ; Emily COOMBS, Auteur ; T. C. WAISMAN, Auteur ; Anne LINDBLOM, Auteur . - p.e70224. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70224 Mots-clés : autism  cultural supports  health outcomes  Indigenous  INSAR SIG  Special Interest Group Index. décimale : PER Périodiques Résumé : ABSTRACT Autism remains understudied and under-detected in Indigenous communities across the globe. This content analysis investigates key themes and future directions for Indigenous autism research, as discussed during a Special Interest Group at the 2025 International Society for Autism Research meeting in Seattle, United States. Discussions and perspectives were explored with shared knowledge from international participants who were service providers, Autistic self-advocates, academics, and other autism-related stakeholders. The emergent themes emphasized the need for autism research in Indigenous communities to utilize approaches that are decolonized, culturally informed, and strengths-based. The results highlighted the need for researchers to focus on building trust, fostering relationship-building, and encouraging collaborative research partnerships with communities, while addressing systemic limiting factors and integrating knowledge systems from Indigenous and Western models. There is also a desire for more Indigenous-led initiatives that allow non-Indigenous researchers to provide support. Overall, there is a clear interest in further Indigenous autism research initiatives, but further shifts are needed to ensure that efforts are community-led and strengths-based. En ligne : https://doi.org/10.1002/aur.70224 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Emotion Dysregulation Predicts Impairments in Peer Interaction and Adaptive Functioning in Autistic Kindergartners / Yeseul SHIN in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70225 Titre : Emotion Dysregulation Predicts Impairments in Peer Interaction and Adaptive Functioning in Autistic Kindergartners Type de document : texte imprimé Auteurs : Yeseul SHIN, Auteur ; Deanna SWAIN, Auteur ; Jeongjin KIM, Auteur ; Seok-Jun HONG, Auteur ; Catherine LORD, Auteur ; So Hyun KIM, Auteur Article en page(s) : p.e70225 Langues : Anglais (eng) Mots-clés : adaptive functioning  autism  emotion dysregulation  longitudinal effect  peer interaction Index. décimale : PER Périodiques Résumé : ABSTRACT Emotion Dysregulation (ED) refers to difficulties in using adaptive strategies to modulate and express emotional arousal in socially appropriate ways. While ED contributes to developmental trajectories including peer engagement, academic achievement, and mental health in neurotypical children, its impact on autistic children is unclear. This study examines whether ED emerging during school transition can affect peer and adaptive functioning in autistic kindergartners. Participants included 64 autistic children at kindergarten-entry (Mage?=?63.06?months) with the majority of children (n?=?53) followed at kindergarten-exit. ED was measured based on the Child Behavioral Checklist-Dysregulation Profile (CBCL-DP scores and severity levels) and the CBCL-Emotion Dysregulation Index scores (CBCL-EDI). Children's peer engagement was examined with the Penn Interactive Peer Play Scale (PIPPS) and adaptive functioning with the Vineland Adaptive Behavior Scales, Third Edition (VABS-3). Hierarchical linear regressions were conducted to examine whether ED at kindergarten-entry predicts peer interaction and adaptive functioning concurrently and longitudinally at kindergarten-exit while controlling for age, gender, nonverbal IQ, and autism symptom severity. One-way ANOVAs were analyzed to compare significant mean differences in peer interactions and adaptive functioning domains across three CBCL-DP severity levels. Higher ED at kindergarten-entry was a strong predictor of impairments in peer and adaptive skills at both kindergarten-entry and -exit. Significant mean differences in peer interaction and adaptive social outcomes were found at both times across CBCL-DP severity levels categorized at kindergarten-entry. Targeted intervention for enhancing ED during the preschool years may optimally support peer engagement and adaptive functioning. En ligne : https://doi.org/10.1002/aur.70225 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Emotion Dysregulation Predicts Impairments in Peer Interaction and Adaptive Functioning in Autistic Kindergartners [texte imprimé] / Yeseul SHIN, Auteur ; Deanna SWAIN, Auteur ; Jeongjin KIM, Auteur ; Seok-Jun HONG, Auteur ; Catherine LORD, Auteur ; So Hyun KIM, Auteur . - p.e70225. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70225 Mots-clés : adaptive functioning  autism  emotion dysregulation  longitudinal effect  peer interaction Index. décimale : PER Périodiques Résumé : ABSTRACT Emotion Dysregulation (ED) refers to difficulties in using adaptive strategies to modulate and express emotional arousal in socially appropriate ways. While ED contributes to developmental trajectories including peer engagement, academic achievement, and mental health in neurotypical children, its impact on autistic children is unclear. This study examines whether ED emerging during school transition can affect peer and adaptive functioning in autistic kindergartners. Participants included 64 autistic children at kindergarten-entry (Mage?=?63.06?months) with the majority of children (n?=?53) followed at kindergarten-exit. ED was measured based on the Child Behavioral Checklist-Dysregulation Profile (CBCL-DP scores and severity levels) and the CBCL-Emotion Dysregulation Index scores (CBCL-EDI). Children's peer engagement was examined with the Penn Interactive Peer Play Scale (PIPPS) and adaptive functioning with the Vineland Adaptive Behavior Scales, Third Edition (VABS-3). Hierarchical linear regressions were conducted to examine whether ED at kindergarten-entry predicts peer interaction and adaptive functioning concurrently and longitudinally at kindergarten-exit while controlling for age, gender, nonverbal IQ, and autism symptom severity. One-way ANOVAs were analyzed to compare significant mean differences in peer interactions and adaptive functioning domains across three CBCL-DP severity levels. Higher ED at kindergarten-entry was a strong predictor of impairments in peer and adaptive skills at both kindergarten-entry and -exit. Significant mean differences in peer interaction and adaptive social outcomes were found at both times across CBCL-DP severity levels categorized at kindergarten-entry. Targeted intervention for enhancing ED during the preschool years may optimally support peer engagement and adaptive functioning. En ligne : https://doi.org/10.1002/aur.70225 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Interval Timing Is Altered in Male Nrxn1+/− Mice: A Model of Autism Spectrum Disorder / Kyle M. RODDICK in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70226 Titre : Interval Timing Is Altered in Male Nrxn1+/− Mice: A Model of Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Kyle M. RODDICK, Auteur ; Elias B. HABIB, Auteur ; Richard E. BROWN, Auteur ; Fuat BALCı, Auteur Article en page(s) : p.e70226 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  genetic murine models  interval timing  mice  neurexin Index. décimale : PER Périodiques Résumé : ABSTRACT Autism spectrum disorder (ASD) is characterized by impaired social interactions and communication, and increased repetitive and stereotypical behavior. Neuroimaging shows functional abnormalities in brain areas involved in temporal processing in autistic individuals, and they also show deficits in interval timing. Neurexin (NRXN) mutations have been identified in a wide variety of neuropsychiatric disorders, including ASD, and Nrxn1+/? mice possess a mutation that disrupts the α, ?, and ? isoforms of Nrxn1, a gene involved in synapse structure. We investigated the interval timing abilities of the Nrxn1+/? mouse model of ASD in the peak interval procedure using a 15-s target interval and compared their performance with that of Nrxn1+/+ and Nrxn1?S5/? rescue mice. Two-month-old male Nrxn1+/+ (C57BL/6?J), Nrxn1+/?, and Nrxn1?S5/? mice were trained to obtain sucrose liquid rewards 15?s after the onset of a discriminative stimulus (discrete fixed-interval training), and their timing responses were tested in non-reinforced probe trials. Our analysis of responses across individual trials revealed that Nrxn1+/? mice had earlier timing responses overall. This difference was manifested as earlier termination of responding in terms of the response curves. These findings are consistent with leftward shifts observed with experimental animal models of ASD. In conclusion, we believe these results indicate a bias in long-term memory in the Nrxn1+/? mouse model of ASD and may capture the timing deficit observed in autistic individuals. En ligne : https://doi.org/10.1002/aur.70226 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Interval Timing Is Altered in Male Nrxn1+/− Mice: A Model of Autism Spectrum Disorder [texte imprimé] / Kyle M. RODDICK, Auteur ; Elias B. HABIB, Auteur ; Richard E. BROWN, Auteur ; Fuat BALCı, Auteur . - p.e70226. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70226 Mots-clés : autism spectrum disorder  genetic murine models  interval timing  mice  neurexin Index. décimale : PER Périodiques Résumé : ABSTRACT Autism spectrum disorder (ASD) is characterized by impaired social interactions and communication, and increased repetitive and stereotypical behavior. Neuroimaging shows functional abnormalities in brain areas involved in temporal processing in autistic individuals, and they also show deficits in interval timing. Neurexin (NRXN) mutations have been identified in a wide variety of neuropsychiatric disorders, including ASD, and Nrxn1+/? mice possess a mutation that disrupts the α, ?, and ? isoforms of Nrxn1, a gene involved in synapse structure. We investigated the interval timing abilities of the Nrxn1+/? mouse model of ASD in the peak interval procedure using a 15-s target interval and compared their performance with that of Nrxn1+/+ and Nrxn1?S5/? rescue mice. Two-month-old male Nrxn1+/+ (C57BL/6?J), Nrxn1+/?, and Nrxn1?S5/? mice were trained to obtain sucrose liquid rewards 15?s after the onset of a discriminative stimulus (discrete fixed-interval training), and their timing responses were tested in non-reinforced probe trials. Our analysis of responses across individual trials revealed that Nrxn1+/? mice had earlier timing responses overall. This difference was manifested as earlier termination of responding in terms of the response curves. These findings are consistent with leftward shifts observed with experimental animal models of ASD. In conclusion, we believe these results indicate a bias in long-term memory in the Nrxn1+/? mouse model of ASD and may capture the timing deficit observed in autistic individuals. En ligne : https://doi.org/10.1002/aur.70226 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Bullying Trajectories From Childhood to Adolescence: The Relationship With Mental Health Outcomes for Autistic and Neurotypical Youth / Emre DENIZ in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70227 Titre : Bullying Trajectories From Childhood to Adolescence: The Relationship With Mental Health Outcomes for Autistic and Neurotypical Youth Type de document : texte imprimé Auteurs : Emre DENIZ, Auteur ; Nathalie NORET, Auteur ; Athena R.W. CHOW, Auteur ; Jessie R. BALDWIN, Auteur ; Umar TOSEEB, Auteur Article en page(s) : p.e70227 Langues : Anglais (eng) Mots-clés : autism  bullying  longitudinal  mental health  social support Index. décimale : PER Périodiques Résumé : ABSTRACT Autistic youth are more likely to be involved in bullying, have poorer mental health, and experience friendships and social support differently compared to neurotypical youth. What remains unclear is whether the relationship between bullying and mental health is different for autistic and neurotypical youth and whether friendships and social support moderate this relationship. In this United Kingdom-based population-based study, we investigated the relationship between bullying involvement, victimization, and perpetration, from early childhood (age 5?years) through to mid-adolescence (age 14?years) with mental health outcomes in later adolescence (age 17?years) for autistic (n?=?576) and neurotypical youth (n?=?14,963). We used parent-, teacher-, and self-reports of bullying at ages 5, 7, 11, and 14?years to identify five bullying trajectory groups (uninvolved, adolescent victim, early childhood victim, early childhood bully, and bully-victims). Autistic youth were more likely than their neurotypical peers to be in one of the bullying trajectory groups compared to being in the uninvolved group. Specifically, 74% of autistic youth experienced bullying either as victims, bullies, or bully-victims between early childhood and adolescence compared to 38% of neurotypical youth. Both autistic and neurotypical youth who were involved in bullying, whether as a perpetrator or victim, experienced poorer subsequent mental health later in adolescence. Higher perceived social support buffered the effects of bullying involvement for neurotypical and, to a lesser extent, autistic youth. These findings highlight the need for further research focusing on possible targets for intervention to mitigate the possible impacts of bullying on subsequent mental health for autistic youth. En ligne : https://doi.org/10.1002/aur.70227 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Bullying Trajectories From Childhood to Adolescence: The Relationship With Mental Health Outcomes for Autistic and Neurotypical Youth [texte imprimé] / Emre DENIZ, Auteur ; Nathalie NORET, Auteur ; Athena R.W. CHOW, Auteur ; Jessie R. BALDWIN, Auteur ; Umar TOSEEB, Auteur . - p.e70227. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70227 Mots-clés : autism  bullying  longitudinal  mental health  social support Index. décimale : PER Périodiques Résumé : ABSTRACT Autistic youth are more likely to be involved in bullying, have poorer mental health, and experience friendships and social support differently compared to neurotypical youth. What remains unclear is whether the relationship between bullying and mental health is different for autistic and neurotypical youth and whether friendships and social support moderate this relationship. In this United Kingdom-based population-based study, we investigated the relationship between bullying involvement, victimization, and perpetration, from early childhood (age 5?years) through to mid-adolescence (age 14?years) with mental health outcomes in later adolescence (age 17?years) for autistic (n?=?576) and neurotypical youth (n?=?14,963). We used parent-, teacher-, and self-reports of bullying at ages 5, 7, 11, and 14?years to identify five bullying trajectory groups (uninvolved, adolescent victim, early childhood victim, early childhood bully, and bully-victims). Autistic youth were more likely than their neurotypical peers to be in one of the bullying trajectory groups compared to being in the uninvolved group. Specifically, 74% of autistic youth experienced bullying either as victims, bullies, or bully-victims between early childhood and adolescence compared to 38% of neurotypical youth. Both autistic and neurotypical youth who were involved in bullying, whether as a perpetrator or victim, experienced poorer subsequent mental health later in adolescence. Higher perceived social support buffered the effects of bullying involvement for neurotypical and, to a lesser extent, autistic youth. These findings highlight the need for further research focusing on possible targets for intervention to mitigate the possible impacts of bullying on subsequent mental health for autistic youth. En ligne : https://doi.org/10.1002/aur.70227 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

The 3-Hit Metabolic Signaling Model for Autism Spectrum Disorder: A Summary / Robert K. NAVIAUX in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70228 Titre : The 3-Hit Metabolic Signaling Model for Autism Spectrum Disorder: A Summary Type de document : texte imprimé Auteurs : Robert K. NAVIAUX, Auteur Article en page(s) : p.e70228 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  CDR stacking  cell danger response  exposomics  metabolic signaling  metabolomics  mitochondria  network analysis  salugenesis Index. décimale : PER Périodiques Résumé : ABSTRACT Autism spectrum disorder (ASD) is a highly heritable yet environmentally sensitive neurodevelopmental condition whose biological heterogeneity has resisted a unifying causal explanation for over 100?years. The 3-hit metabolic signaling model proposes that ASD arises from abnormal persistence of an evolutionarily conserved stress-response program?the cell danger response (CDR)?during critical windows of neurodevelopment. In this framework, ASD emerges from the sequential interaction of: (1) inherited genetic or epigenetic variants that sensitize mitochondrial metabolism, intracellular calcium handling, and purinergic signaling to environmental change; (2) early prenatal or postnatal activation of the CDR by infection, immune dysregulation, metabolic disturbance, or environmental toxicant exposure; and (3) prolonged or recurrent exposure to CDR-activating triggers for 3?6?months from the late 1st trimester to 18?36?months of age. The CDR is initiated by extracellular ATP (eATP)-associated purinergic signaling and mitochondrial changes that are resource- and energy-intensive. Persistent or recurrent activation of the CDR during the critical neurodevelopmental window is proposed to sensitize developing cells to eATP-related signaling, leading to false alarms and a mixture of chemical, immune, and neurosensory under- and over-responsivity. More frequent cycles of CDR activation and recovery are proposed to cause cellular competition for key bioenergetic, mitochondrial, and metabolic resources needed to support the normal trajectory of child development. Phenylketonuria (PKU) provides a proof-of-principle example. Untreated PKU historically caused intellectual disability and autistic features, while universal newborn screening and early treatment interrupt this sequence and prevent or decrease these outcomes despite strong genetic predisposition. En ligne : https://doi.org/10.1002/aur.70228 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] The 3-Hit Metabolic Signaling Model for Autism Spectrum Disorder: A Summary [texte imprimé] / Robert K. NAVIAUX, Auteur . - p.e70228. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70228 Mots-clés : autism spectrum disorder  CDR stacking  cell danger response  exposomics  metabolic signaling  metabolomics  mitochondria  network analysis  salugenesis Index. décimale : PER Périodiques Résumé : ABSTRACT Autism spectrum disorder (ASD) is a highly heritable yet environmentally sensitive neurodevelopmental condition whose biological heterogeneity has resisted a unifying causal explanation for over 100?years. The 3-hit metabolic signaling model proposes that ASD arises from abnormal persistence of an evolutionarily conserved stress-response program?the cell danger response (CDR)?during critical windows of neurodevelopment. In this framework, ASD emerges from the sequential interaction of: (1) inherited genetic or epigenetic variants that sensitize mitochondrial metabolism, intracellular calcium handling, and purinergic signaling to environmental change; (2) early prenatal or postnatal activation of the CDR by infection, immune dysregulation, metabolic disturbance, or environmental toxicant exposure; and (3) prolonged or recurrent exposure to CDR-activating triggers for 3?6?months from the late 1st trimester to 18?36?months of age. The CDR is initiated by extracellular ATP (eATP)-associated purinergic signaling and mitochondrial changes that are resource- and energy-intensive. Persistent or recurrent activation of the CDR during the critical neurodevelopmental window is proposed to sensitize developing cells to eATP-related signaling, leading to false alarms and a mixture of chemical, immune, and neurosensory under- and over-responsivity. More frequent cycles of CDR activation and recovery are proposed to cause cellular competition for key bioenergetic, mitochondrial, and metabolic resources needed to support the normal trajectory of child development. Phenylketonuria (PKU) provides a proof-of-principle example. Untreated PKU historically caused intellectual disability and autistic features, while universal newborn screening and early treatment interrupt this sequence and prevent or decrease these outcomes despite strong genetic predisposition. En ligne : https://doi.org/10.1002/aur.70228 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

The E3 Ubiquitin Ligase UBE3B Regulates Synaptic Development and Cortical Network Activity / Shayal VASHISTH in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70229 Titre : The E3 Ubiquitin Ligase UBE3B Regulates Synaptic Development and Cortical Network Activity Type de document : texte imprimé Auteurs : Shayal VASHISTH, Auteur ; Aleya SHEDD, Auteur ; Ariel AIKEN, Auteur ; Solmi CHEON, Auteur ; Josh BANDOPADHAY, Auteur ; Kiran KAUR, Auteur ; Kimberly M. HUBER, Auteur ; Maria H. CHAHROUR, Auteur Article en page(s) : p.e70229 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired communication, abnormal social interactions, and restricted, repetitive behaviors. Pathogenic mutations in UBE3B result in neurodevelopmental disease, including intellectual disability, lack of speech, and ASD. UBE3B is an E3 ubiquitin ligase that tags substrate proteins with ubiquitin, marking them for proteasomal degradation. The ubiquitin-proteasome system (UPS) regulates several signaling pathways critical for neurodevelopment, including neurogenesis and synaptogenesis, and mutations in various UPS genes have been identified in ASD and related neurodevelopmental disorders. To investigate the function of UBE3B in the brain and how its disruption gives rise to neurodevelopmental abnormalities, we generated a central nervous system-specific conditional Ube3b knockout (cKO) mouse model and evaluated the resulting neurobehavioral phenotypes. We found that Ube3b cKO mice exhibit severe deficits in vocalization, social behavior, learning and memory, and motor skills. Assessment of in vivo neuronal phenotypes revealed defects in dendritic morphogenesis, reduced excitatory synapse density, diminished spontaneous cortical circuit activity, decreased AMPA receptor surface expression, and hyperexcitability of excitatory cortical neurons. Using quantitative proteomics, we profiled the proteome and ubiquitome of neural stem cells and identified 116 proteins that exhibited increased protein levels and reduced ubiquitination following loss of UBE3B. These proteins were highly enriched for ones involved in synaptic processes, and we confirmed interaction of UBE3B with several key synaptic proteins, including ATP1A1, DOCK7, NLGN2, and STX12. Collectively, our findings identify a role for UBE3B in regulating social, cognitive, and motor functions, and neuronal morphogenesis and activity by fine-tuning the synaptic proteome. En ligne : https://doi.org/10.1002/aur.70229 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] The E3 Ubiquitin Ligase UBE3B Regulates Synaptic Development and Cortical Network Activity [texte imprimé] / Shayal VASHISTH, Auteur ; Aleya SHEDD, Auteur ; Ariel AIKEN, Auteur ; Solmi CHEON, Auteur ; Josh BANDOPADHAY, Auteur ; Kiran KAUR, Auteur ; Kimberly M. HUBER, Auteur ; Maria H. CHAHROUR, Auteur . - p.e70229. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70229 Index. décimale : PER Périodiques Résumé : ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired communication, abnormal social interactions, and restricted, repetitive behaviors. Pathogenic mutations in UBE3B result in neurodevelopmental disease, including intellectual disability, lack of speech, and ASD. UBE3B is an E3 ubiquitin ligase that tags substrate proteins with ubiquitin, marking them for proteasomal degradation. The ubiquitin-proteasome system (UPS) regulates several signaling pathways critical for neurodevelopment, including neurogenesis and synaptogenesis, and mutations in various UPS genes have been identified in ASD and related neurodevelopmental disorders. To investigate the function of UBE3B in the brain and how its disruption gives rise to neurodevelopmental abnormalities, we generated a central nervous system-specific conditional Ube3b knockout (cKO) mouse model and evaluated the resulting neurobehavioral phenotypes. We found that Ube3b cKO mice exhibit severe deficits in vocalization, social behavior, learning and memory, and motor skills. Assessment of in vivo neuronal phenotypes revealed defects in dendritic morphogenesis, reduced excitatory synapse density, diminished spontaneous cortical circuit activity, decreased AMPA receptor surface expression, and hyperexcitability of excitatory cortical neurons. Using quantitative proteomics, we profiled the proteome and ubiquitome of neural stem cells and identified 116 proteins that exhibited increased protein levels and reduced ubiquitination following loss of UBE3B. These proteins were highly enriched for ones involved in synaptic processes, and we confirmed interaction of UBE3B with several key synaptic proteins, including ATP1A1, DOCK7, NLGN2, and STX12. Collectively, our findings identify a role for UBE3B in regulating social, cognitive, and motor functions, and neuronal morphogenesis and activity by fine-tuning the synaptic proteome. En ligne : https://doi.org/10.1002/aur.70229 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Auditory P100m and Language Difficulties in Children With ASD: Effects of Vowel-Like Acoustic Structure / Kirill A. FADEEV in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70232 Titre : Auditory P100m and Language Difficulties in Children With ASD: Effects of Vowel-Like Acoustic Structure Type de document : texte imprimé Auteurs : Kirill A. FADEEV, Auteur ; Ilacai V. ROMERO REYES, Auteur ; Dzerassa E. GOIAEVA, Auteur ; Tatiana M. OVSIANNIKOVA, Auteur ; Andrey O. PROKOFYEV, Auteur ; Anna M. RYTIKOVA, Auteur ; Artem Y. NOVIKOV, Auteur ; Tatiana A. STROGANOVA, Auteur ; Elena V. OREKHOVA, Auteur Article en page(s) : p.e70232 Langues : Anglais (eng) Mots-clés : auditory evoked fields  autism spectrum disorders (ASD)  language  magnetoencephalography (MEG)  P100m/M50/P100/  sustained negativity Index. décimale : PER Périodiques Résumé : ABSTRACT The P100/P100m component of auditory event-related potentials/fields is considered a potential biomarker of atypical arousal and language difficulties in children with ASD. When elicited by complex speech-like sounds with regular temporal or frequency structure, P100/P100m may be influenced by sustained negativity (SN), which can reduce its amplitude due to opposing current polarity and contribute to ASD-related differences. Using magnetoencephalography (MEG), we examined P100m responses to acoustic regularities in the left and right auditory cortices in 35 ASD and 39 TD boys (7?12?years). Stimuli included (1) temporally and spectrally regular sounds (periodic vowels), (2) temporally regular sounds (periodic non-vowels), (3) spectrally regular sounds (non-periodic vowels), as well as (4) non-regular control stimuli (non-periodic, non-vowels). P100m was estimated using distributed source localization. Both groups showed decreased P100m amplitude and latency with acoustic regularities, accompanied by proportional SN increases, suggesting P100m modulation primarily reflects early SN enhancement. No group differences were observed in P100m latency or amplitude, and their modulation by stimulus type was also normal in ASD, indicating spared processing of acoustic regularities in the P100m time range. However, P100m latencies variability was increased in boys with ASD, and their left P100m amplitudes to both non-regular and regular sounds were negatively associated with cumulative language and intellectual abilities. These findings suggest that while most children with ASD show typical P100m responses, individual variations in P100m amplitude may reflect neurodevelopmental differences in cortical maturation and/or sensory habituation processes that contribute to the heterogeneity of cognitive and language abilities in ASD. En ligne : https://doi.org/10.1002/aur.70232 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Auditory P100m and Language Difficulties in Children With ASD: Effects of Vowel-Like Acoustic Structure [texte imprimé] / Kirill A. FADEEV, Auteur ; Ilacai V. ROMERO REYES, Auteur ; Dzerassa E. GOIAEVA, Auteur ; Tatiana M. OVSIANNIKOVA, Auteur ; Andrey O. PROKOFYEV, Auteur ; Anna M. RYTIKOVA, Auteur ; Artem Y. NOVIKOV, Auteur ; Tatiana A. STROGANOVA, Auteur ; Elena V. OREKHOVA, Auteur . - p.e70232. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70232 Mots-clés : auditory evoked fields  autism spectrum disorders (ASD)  language  magnetoencephalography (MEG)  P100m/M50/P100/  sustained negativity Index. décimale : PER Périodiques Résumé : ABSTRACT The P100/P100m component of auditory event-related potentials/fields is considered a potential biomarker of atypical arousal and language difficulties in children with ASD. When elicited by complex speech-like sounds with regular temporal or frequency structure, P100/P100m may be influenced by sustained negativity (SN), which can reduce its amplitude due to opposing current polarity and contribute to ASD-related differences. Using magnetoencephalography (MEG), we examined P100m responses to acoustic regularities in the left and right auditory cortices in 35 ASD and 39 TD boys (7?12?years). Stimuli included (1) temporally and spectrally regular sounds (periodic vowels), (2) temporally regular sounds (periodic non-vowels), (3) spectrally regular sounds (non-periodic vowels), as well as (4) non-regular control stimuli (non-periodic, non-vowels). P100m was estimated using distributed source localization. Both groups showed decreased P100m amplitude and latency with acoustic regularities, accompanied by proportional SN increases, suggesting P100m modulation primarily reflects early SN enhancement. No group differences were observed in P100m latency or amplitude, and their modulation by stimulus type was also normal in ASD, indicating spared processing of acoustic regularities in the P100m time range. However, P100m latencies variability was increased in boys with ASD, and their left P100m amplitudes to both non-regular and regular sounds were negatively associated with cumulative language and intellectual abilities. These findings suggest that while most children with ASD show typical P100m responses, individual variations in P100m amplitude may reflect neurodevelopmental differences in cortical maturation and/or sensory habituation processes that contribute to the heterogeneity of cognitive and language abilities in ASD. En ligne : https://doi.org/10.1002/aur.70232 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Optimizing Accuracy of Autism Diagnostic Observation Schedule-2 in Very Young Children With Modifying the Effect of Global Developmental Delay / Jacqueline LIU in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70233 Titre : Optimizing Accuracy of Autism Diagnostic Observation Schedule-2 in Very Young Children With Modifying the Effect of Global Developmental Delay Type de document : texte imprimé Auteurs : Jacqueline LIU, Auteur ; Qing LU, Auteur ; Vini SINGH, Auteur ; Stephanie CHOI, Auteur ; Elizabeth A. CROSS, Auteur ; Ji Su HONG, Auteur Article en page(s) : p.e70233 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : ABSTRACT The current study investigated 1144 toddlers and preschoolers (ASD?+?GDD n?=?592; ASD only n?=?249; GDD only n?=?89; no ASD or GDD n?=?214) with the toddler module (38.6%), Module 1 (57.5%), and Module 2 (3.9%) as well as Mullen Scales of Early Learning. The calibrated severity score (CSS) was used to compare severity across modules. The study sample was stratified by GDD (Visual Reception Developmental Quotient? En ligne : https://doi.org/10.1002/aur.70233 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Optimizing Accuracy of Autism Diagnostic Observation Schedule-2 in Very Young Children With Modifying the Effect of Global Developmental Delay [texte imprimé] / Jacqueline LIU, Auteur ; Qing LU, Auteur ; Vini SINGH, Auteur ; Stephanie CHOI, Auteur ; Elizabeth A. CROSS, Auteur ; Ji Su HONG, Auteur . - p.e70233. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70233 Index. décimale : PER Périodiques Résumé : ABSTRACT The current study investigated 1144 toddlers and preschoolers (ASD?+?GDD n?=?592; ASD only n?=?249; GDD only n?=?89; no ASD or GDD n?=?214) with the toddler module (38.6%), Module 1 (57.5%), and Module 2 (3.9%) as well as Mullen Scales of Early Learning. The calibrated severity score (CSS) was used to compare severity across modules. The study sample was stratified by GDD (Visual Reception Developmental Quotient? En ligne : https://doi.org/10.1002/aur.70233 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Autism Spectrum Disorder Among Gender-Diverse Children and Adolescents: A National Cohort Study / Erez TOPAZ in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70235 Titre : Autism Spectrum Disorder Among Gender-Diverse Children and Adolescents: A National Cohort Study Type de document : texte imprimé Auteurs : Erez TOPAZ, Auteur ; Tamar SHEPPES, Auteur ; Anat SEGEV-BECKER, Auteur ; Galit ISRAELI, Auteur ; Asaf OREN, Auteur ; Yael LEBENTHAL, Auteur ; Tomer SHECHNER, Auteur ; Liat PERL, Auteur Article en page(s) : p.e70235 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  gender identity  gender-affirming care  health services accessibility  mental health  pediatrics  transgender persons Index. décimale : PER Périodiques Résumé : ABSTRACT Autism spectrum disorder (ASD) is more prevalent in transgender and gender-diverse (TGD) individuals than in the general population, yet the specific developmental pathways within and clinical outcomes of this intersection are insufficiently understood. This study examined how ASD and sex assigned at birth (SAAB) are associated with gender-related milestones, access to gender-affirming consultation and care (GACC), and psychiatric outcomes. We reviewed electronic medical records for 786 TGD children and adolescents (aged 4?19?years) presenting to a national referral clinic between 2013 and 2025. Demographic, developmental, and psychiatric variables were analyzed across four ASD-by-SAAB groups using generalized linear models and logistic regressions, with Bonferroni-adjusted post hoc comparisons (α?=?0.0083). ASD was documented in 9.7% of the cohort, with referrals of autistic TGD patients increasing significantly over time. Autistic patients presented with a distinct profile, characterized by higher socioeconomic position (SEP), intellectual giftedness, non-binary gender identity, and an earlier stage of pubertal development at presentation. Crucially, while ages at gender-related milestones were largely comparable between neurotypes, autistic assigned female at birth (AFAB) adolescents were significantly less likely to initiate puberty suppression or gender-affirming hormones than their non-autistic peers. Furthermore, higher SEP was associated with earlier clinical presentation only for non-autistic youth. Autistic TGD patients exhibited a higher psychiatric burden, with an ASD diagnosis uniquely associated with elevated rates of anxiety, ADHD, and psychotropic medication use. These findings reveal a disparity between developmental synchrony and clinical access, underscoring the need for autism-informed protocols to support equitable gender-affirming care. En ligne : https://doi.org/10.1002/aur.70235 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Autism Spectrum Disorder Among Gender-Diverse Children and Adolescents: A National Cohort Study [texte imprimé] / Erez TOPAZ, Auteur ; Tamar SHEPPES, Auteur ; Anat SEGEV-BECKER, Auteur ; Galit ISRAELI, Auteur ; Asaf OREN, Auteur ; Yael LEBENTHAL, Auteur ; Tomer SHECHNER, Auteur ; Liat PERL, Auteur . - p.e70235. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70235 Mots-clés : autism spectrum disorder  gender identity  gender-affirming care  health services accessibility  mental health  pediatrics  transgender persons Index. décimale : PER Périodiques Résumé : ABSTRACT Autism spectrum disorder (ASD) is more prevalent in transgender and gender-diverse (TGD) individuals than in the general population, yet the specific developmental pathways within and clinical outcomes of this intersection are insufficiently understood. This study examined how ASD and sex assigned at birth (SAAB) are associated with gender-related milestones, access to gender-affirming consultation and care (GACC), and psychiatric outcomes. We reviewed electronic medical records for 786 TGD children and adolescents (aged 4?19?years) presenting to a national referral clinic between 2013 and 2025. Demographic, developmental, and psychiatric variables were analyzed across four ASD-by-SAAB groups using generalized linear models and logistic regressions, with Bonferroni-adjusted post hoc comparisons (α?=?0.0083). ASD was documented in 9.7% of the cohort, with referrals of autistic TGD patients increasing significantly over time. Autistic patients presented with a distinct profile, characterized by higher socioeconomic position (SEP), intellectual giftedness, non-binary gender identity, and an earlier stage of pubertal development at presentation. Crucially, while ages at gender-related milestones were largely comparable between neurotypes, autistic assigned female at birth (AFAB) adolescents were significantly less likely to initiate puberty suppression or gender-affirming hormones than their non-autistic peers. Furthermore, higher SEP was associated with earlier clinical presentation only for non-autistic youth. Autistic TGD patients exhibited a higher psychiatric burden, with an ASD diagnosis uniquely associated with elevated rates of anxiety, ADHD, and psychotropic medication use. These findings reveal a disparity between developmental synchrony and clinical access, underscoring the need for autism-informed protocols to support equitable gender-affirming care. En ligne : https://doi.org/10.1002/aur.70235 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Language and Repetition Performance in Autism Spectrum Disorder Versus Developmental Language Disorder: Evidence From Turkish-Speaking Children / Dilber KAÇAR KÜTÜKÇÜ in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70236 Titre : Language and Repetition Performance in Autism Spectrum Disorder Versus Developmental Language Disorder: Evidence From Turkish-Speaking Children Type de document : texte imprimé Auteurs : Dilber KAÇAR KÜTÜKÇÜ, Auteur ; Fenise Selin KARALı, Auteur ; Nilgün ÇıNAR, Auteur Article en page(s) : p.e70236 Langues : Anglais (eng) Mots-clés : assessment  autism spectrum disorder  developmental language disorder  language  neurodevelopmental conditions Index. décimale : PER Périodiques Résumé : ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by persistent differences in social communication and interaction, as well as restricted and repetitive patterns of behavior, interests, or activities. Language difficulties are common in autism and can affect multiple domains, including phonology, morphology, syntax, semantics, and pragmatics. This study examined the language and repetition skills of Turkish-speaking autistic children (diagnosed with ASD), children with developmental language disorder (DLD), and typically developing (TD) peers. Ninety children aged 5?9?years participated: 30 autistic children, 30 children with DLD, and 30 TD children. Language abilities were assessed using the Turkish School Age Language Development Test (TOD?L), the LITMUS Turkish Sentence Repetition Test (LITMUS-TR), and the Turkish Nonword Repetition Test (TAST). The TD group scored significantly higher than both clinical groups across all measures. In direct comparisons between the clinical groups, autistic children had lower scores than children with DLD on several morphosyntactic and lexical?semantic measures. After Bonferroni correction, only morpheme completion (TOD?L BT) differed significantly between the groups; associated vocabulary (TOD?L IS) and word description (TOD?L SB) showed smaller differences that did not reach the Bonferroni-adjusted significance threshold. The two clinical groups showed similar performance on picture vocabulary (TOD?L RS), sentence comprehension (TOD?L CA), sentence repetition (TOD?L CT; LITMUS-TR), and nonword repetition (TAST). The findings indicate specific areas of relative difficulty in morphosyntactic and lexical?semantic processing among autistic children in this sample, alongside broadly similar performance to children with DLD on other sentence-level and repetition measures. These results suggest the potential value of tailored, evidence-based interventions that consider autistic children's individual language profiles, while also taking into account broader cognitive and executive functioning needs. En ligne : https://doi.org/10.1002/aur.70236 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Language and Repetition Performance in Autism Spectrum Disorder Versus Developmental Language Disorder: Evidence From Turkish-Speaking Children [texte imprimé] / Dilber KAÇAR KÜTÜKÇÜ, Auteur ; Fenise Selin KARALı, Auteur ; Nilgün ÇıNAR, Auteur . - p.e70236. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70236 Mots-clés : assessment  autism spectrum disorder  developmental language disorder  language  neurodevelopmental conditions Index. décimale : PER Périodiques Résumé : ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by persistent differences in social communication and interaction, as well as restricted and repetitive patterns of behavior, interests, or activities. Language difficulties are common in autism and can affect multiple domains, including phonology, morphology, syntax, semantics, and pragmatics. This study examined the language and repetition skills of Turkish-speaking autistic children (diagnosed with ASD), children with developmental language disorder (DLD), and typically developing (TD) peers. Ninety children aged 5?9?years participated: 30 autistic children, 30 children with DLD, and 30 TD children. Language abilities were assessed using the Turkish School Age Language Development Test (TOD?L), the LITMUS Turkish Sentence Repetition Test (LITMUS-TR), and the Turkish Nonword Repetition Test (TAST). The TD group scored significantly higher than both clinical groups across all measures. In direct comparisons between the clinical groups, autistic children had lower scores than children with DLD on several morphosyntactic and lexical?semantic measures. After Bonferroni correction, only morpheme completion (TOD?L BT) differed significantly between the groups; associated vocabulary (TOD?L IS) and word description (TOD?L SB) showed smaller differences that did not reach the Bonferroni-adjusted significance threshold. The two clinical groups showed similar performance on picture vocabulary (TOD?L RS), sentence comprehension (TOD?L CA), sentence repetition (TOD?L CT; LITMUS-TR), and nonword repetition (TAST). The findings indicate specific areas of relative difficulty in morphosyntactic and lexical?semantic processing among autistic children in this sample, alongside broadly similar performance to children with DLD on other sentence-level and repetition measures. These results suggest the potential value of tailored, evidence-based interventions that consider autistic children's individual language profiles, while also taking into account broader cognitive and executive functioning needs. En ligne : https://doi.org/10.1002/aur.70236 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

The Role of Microbiota Metabolites Propionic Acid, p-Cresol, and 4-Ethylphenyl Sulfate in Autism Susceptibility: A Systematic Review / Laura SANDONI in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70237 Titre : The Role of Microbiota Metabolites Propionic Acid, p-Cresol, and 4-Ethylphenyl Sulfate in Autism Susceptibility: A Systematic Review Type de document : texte imprimé Auteurs : Laura SANDONI, Auteur ; Lisa ASTA, Auteur ; Nicole GIOMPAOLO, Auteur ; Rinvil RENALDI, Auteur ; Alberto AMARETTI, Auteur ; Maddalena ROSSI, Auteur ; Antonio M. PERSICO, Auteur Article en page(s) : p.e70237 Langues : Anglais (eng) Mots-clés : 4-ethylphenyl sulfate  autism spectrum disorder  gut microbiota  gut-brain axis  propionic acid  p-cresol Index. décimale : PER Périodiques Résumé : ABSTRACT The etiopathogenesis of Autism Spectrum Disorder (ASD) encompasses complex interactions between genetic and environmental risk factors. The high prevalence of gastrointestinal disorders in autistic individuals has propelled a growing interest in the possible involvement of gut dysbiosis in ASD pathogenesis. Thousands of different bacterial strains are found in the human gut, which produce numerous metabolites that can enter the bloodstream and often pass the blood?brain barrier, potentially influencing neurodevelopment and brain function. This systematic review aims to provide a comprehensive outlook on the role of three metabolic compounds derived from gut bacteria, propionic acid (PPA), p-cresol, and 4-ethylphenyl sulfate (4-EPS), in modulating neuronal function and conferring susceptibility to ASD. To achieve this, we screened 411 records collected through a systematic search of current scientific literature in PubMed, Web of Science, and Scopus, ultimately reviewing a total of 90 records, which included data from ASD human cohorts as well as animal and cellular models of autism. Human studies provided compelling evidence of altered metabolic profiles in ASD individuals, especially for PPA and p-cresol, but also to a smaller extent, for 4-EPS. Furthermore, data obtained from the exposure of experimental models to each one of these three metabolic compounds identified several behavioral anomalies induced in treated animals and highlighted common neurobiological mechanisms. Overall, current literature supports the contribution of gut metabolites to ASD susceptibility and/or a significant modulatory role on the clinical expression of ASD, strongly encouraging further research in the field in order to improve autism diagnostics and management. En ligne : https://doi.org/10.1002/aur.70237 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] The Role of Microbiota Metabolites Propionic Acid, p-Cresol, and 4-Ethylphenyl Sulfate in Autism Susceptibility: A Systematic Review [texte imprimé] / Laura SANDONI, Auteur ; Lisa ASTA, Auteur ; Nicole GIOMPAOLO, Auteur ; Rinvil RENALDI, Auteur ; Alberto AMARETTI, Auteur ; Maddalena ROSSI, Auteur ; Antonio M. PERSICO, Auteur . - p.e70237. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70237 Mots-clés : 4-ethylphenyl sulfate  autism spectrum disorder  gut microbiota  gut-brain axis  propionic acid  p-cresol Index. décimale : PER Périodiques Résumé : ABSTRACT The etiopathogenesis of Autism Spectrum Disorder (ASD) encompasses complex interactions between genetic and environmental risk factors. The high prevalence of gastrointestinal disorders in autistic individuals has propelled a growing interest in the possible involvement of gut dysbiosis in ASD pathogenesis. Thousands of different bacterial strains are found in the human gut, which produce numerous metabolites that can enter the bloodstream and often pass the blood?brain barrier, potentially influencing neurodevelopment and brain function. This systematic review aims to provide a comprehensive outlook on the role of three metabolic compounds derived from gut bacteria, propionic acid (PPA), p-cresol, and 4-ethylphenyl sulfate (4-EPS), in modulating neuronal function and conferring susceptibility to ASD. To achieve this, we screened 411 records collected through a systematic search of current scientific literature in PubMed, Web of Science, and Scopus, ultimately reviewing a total of 90 records, which included data from ASD human cohorts as well as animal and cellular models of autism. Human studies provided compelling evidence of altered metabolic profiles in ASD individuals, especially for PPA and p-cresol, but also to a smaller extent, for 4-EPS. Furthermore, data obtained from the exposure of experimental models to each one of these three metabolic compounds identified several behavioral anomalies induced in treated animals and highlighted common neurobiological mechanisms. Overall, current literature supports the contribution of gut metabolites to ASD susceptibility and/or a significant modulatory role on the clinical expression of ASD, strongly encouraging further research in the field in order to improve autism diagnostics and management. En ligne : https://doi.org/10.1002/aur.70237 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Association Between Healthy Lifestyle Behaviors and Mental Health Symptoms in Children With Autism and ADHD: A Latent Profile Analysis / Matthew BOURKE in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70238 Titre : Association Between Healthy Lifestyle Behaviors and Mental Health Symptoms in Children With Autism and ADHD: A Latent Profile Analysis Type de document : texte imprimé Auteurs : Matthew BOURKE, Auteur ; Jacqueline L. WALKER, Auteur ; George THOMAS, Auteur ; Kathryn FORTNUM, Auteur ; Martin O'FLAHERTY, Auteur Article en page(s) : p.e70238 Langues : Anglais (eng) Mots-clés : children  diet  mental health  neurodevelopmental disorder  physical activity  screen time  sleep Index. décimale : PER Périodiques Résumé : ABSTRACT Healthy lifestyle behaviors, including physical activity, screen time, sleep, and diet quality, are important determinants of mental health, yet little is known about how these behaviors cluster among children with neurodevelopmental disorders. This study identified lifestyle profiles in children with autism and ADHD and examined associations with internalizing, externalizing, and irritability symptoms. Parents of children with a diagnosis of autism and ADHD (n?=?523, 7?12?years, 67% male) reported on lifestyle behaviors and mental health outcomes. Latent profile analysis supported a four-profile solution that balanced statistical fit, parsimony, and theoretical interpretability. Profile 1 (19%) was characterized by very high levels of physical activity, moderate sedentary screen time, relatively high sleep, and above average diet quality. Profile 2 (50%) represented a balanced lifestyle, with moderate activity and sedentary screen time, adequate sleep, and the highest diet quality. Profile 3 (20%) showed low activity, elevated sedentary screen time, adequate sleep, and poor diet quality, while Profile 4 (11%) was defined by extremely high sedentary screen time, low activity, adequate sleep, and poor diet. Children in less healthy profiles characterized by high screen time and poor diet quality reported significantly higher internalizing symptoms compared to the highly active group. However, externalizing symptoms were highest in the highly active profile, and irritability was lowest in the balanced profile relative to both high activity and high screen time groups. Findings suggest that while very high physical activity may protect against internalizing symptoms, a balanced lifestyle combining moderate activity, limited screen use, adequate sleep, and good diet quality may best mental health in children with autism and ADHD. En ligne : https://doi.org/10.1002/aur.70238 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Association Between Healthy Lifestyle Behaviors and Mental Health Symptoms in Children With Autism and ADHD: A Latent Profile Analysis [texte imprimé] / Matthew BOURKE, Auteur ; Jacqueline L. WALKER, Auteur ; George THOMAS, Auteur ; Kathryn FORTNUM, Auteur ; Martin O'FLAHERTY, Auteur . - p.e70238. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70238 Mots-clés : children  diet  mental health  neurodevelopmental disorder  physical activity  screen time  sleep Index. décimale : PER Périodiques Résumé : ABSTRACT Healthy lifestyle behaviors, including physical activity, screen time, sleep, and diet quality, are important determinants of mental health, yet little is known about how these behaviors cluster among children with neurodevelopmental disorders. This study identified lifestyle profiles in children with autism and ADHD and examined associations with internalizing, externalizing, and irritability symptoms. Parents of children with a diagnosis of autism and ADHD (n?=?523, 7?12?years, 67% male) reported on lifestyle behaviors and mental health outcomes. Latent profile analysis supported a four-profile solution that balanced statistical fit, parsimony, and theoretical interpretability. Profile 1 (19%) was characterized by very high levels of physical activity, moderate sedentary screen time, relatively high sleep, and above average diet quality. Profile 2 (50%) represented a balanced lifestyle, with moderate activity and sedentary screen time, adequate sleep, and the highest diet quality. Profile 3 (20%) showed low activity, elevated sedentary screen time, adequate sleep, and poor diet quality, while Profile 4 (11%) was defined by extremely high sedentary screen time, low activity, adequate sleep, and poor diet. Children in less healthy profiles characterized by high screen time and poor diet quality reported significantly higher internalizing symptoms compared to the highly active group. However, externalizing symptoms were highest in the highly active profile, and irritability was lowest in the balanced profile relative to both high activity and high screen time groups. Findings suggest that while very high physical activity may protect against internalizing symptoms, a balanced lifestyle combining moderate activity, limited screen use, adequate sleep, and good diet quality may best mental health in children with autism and ADHD. En ligne : https://doi.org/10.1002/aur.70238 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Language Abilities Associated With Household Income and Parental Education Level in Autistic Children During Early Childhood / Hosanna KIM in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70239 Titre : Language Abilities Associated With Household Income and Parental Education Level in Autistic Children During Early Childhood Type de document : texte imprimé Auteurs : Hosanna KIM, Auteur ; Andrew DAKOPOLOS, Auteur ; Danielle HARVEY, Auteur ; Olivia SURGENT, Auteur ; Brianna HEATH, Auteur ; David G. AMARAL, Auteur ; Sally J. ROGERS, Auteur ; Marjorie SOLOMON, Auteur ; Christine Wu NORDAHL, Auteur ; Derek Sayre ANDREWS, Auteur Article en page(s) : p.e70239 Langues : Anglais (eng) Mots-clés : autism  early childhood  household income  language  socioeconomic factors Index. décimale : PER Périodiques Résumé : ABSTRACT Socioeconomic factors, such as poverty, can significantly impact developmental outcomes. While well-studied in neurotypical children, limited research exists on the impact of these factors on autistic children's development, especially in early childhood. We examined the relationships between two socioeconomic factors, household income and parental education, with cognitive and behavioral profiles in a sample of 308 autistic children aged 2?3.5?years. We found that higher household income and parental education level were significantly associated with higher language abilities and lower externalizing behaviors. Moreover, autistic children from families with below-average income had lower language abilities compared to those from families with average or above-average income. The effects of household income and parental education level remained significant even after controlling for one another. Our findings suggest that lower parental education level and household income, particularly among families from the lowest economic backgrounds, significantly impact language abilities in young autistic children and may contribute to the development of externalizing behaviors, a pattern similar to that observed in non-autistic children. Given that early language abilities are predictive of adulthood outcomes in autism, these findings underscore the importance of supporting socioeconomic stability in the first two to three years of life for autistic children and providing appropriate early interventions to promote language development. En ligne : https://doi.org/10.1002/aur.70239 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Language Abilities Associated With Household Income and Parental Education Level in Autistic Children During Early Childhood [texte imprimé] / Hosanna KIM, Auteur ; Andrew DAKOPOLOS, Auteur ; Danielle HARVEY, Auteur ; Olivia SURGENT, Auteur ; Brianna HEATH, Auteur ; David G. AMARAL, Auteur ; Sally J. ROGERS, Auteur ; Marjorie SOLOMON, Auteur ; Christine Wu NORDAHL, Auteur ; Derek Sayre ANDREWS, Auteur . - p.e70239. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70239 Mots-clés : autism  early childhood  household income  language  socioeconomic factors Index. décimale : PER Périodiques Résumé : ABSTRACT Socioeconomic factors, such as poverty, can significantly impact developmental outcomes. While well-studied in neurotypical children, limited research exists on the impact of these factors on autistic children's development, especially in early childhood. We examined the relationships between two socioeconomic factors, household income and parental education, with cognitive and behavioral profiles in a sample of 308 autistic children aged 2?3.5?years. We found that higher household income and parental education level were significantly associated with higher language abilities and lower externalizing behaviors. Moreover, autistic children from families with below-average income had lower language abilities compared to those from families with average or above-average income. The effects of household income and parental education level remained significant even after controlling for one another. Our findings suggest that lower parental education level and household income, particularly among families from the lowest economic backgrounds, significantly impact language abilities in young autistic children and may contribute to the development of externalizing behaviors, a pattern similar to that observed in non-autistic children. Given that early language abilities are predictive of adulthood outcomes in autism, these findings underscore the importance of supporting socioeconomic stability in the first two to three years of life for autistic children and providing appropriate early interventions to promote language development. En ligne : https://doi.org/10.1002/aur.70239 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Assisted Communication Cannot Bypass Objective Research Investigation / Helen TAGER-FLUSBERG in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70257 Titre : Assisted Communication Cannot Bypass Objective Research Investigation Type de document : texte imprimé Auteurs : Helen TAGER-FLUSBERG, Auteur Article en page(s) : p.e70257 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.70257 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Assisted Communication Cannot Bypass Objective Research Investigation [texte imprimé] / Helen TAGER-FLUSBERG, Auteur . - p.e70257. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70257 Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.70257 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Inaccurate Claims in a Recent Commentary Supporting Facilitated Communication / Katharine BEALS in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70258 Titre : Inaccurate Claims in a Recent Commentary Supporting Facilitated Communication Type de document : texte imprimé Auteurs : Katharine BEALS, Auteur ; Bronwyn HEMSLEY, Auteur ; Russell LANG, Auteur ; Howard SHANE, Auteur Article en page(s) : p.e70258 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.70258 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Inaccurate Claims in a Recent Commentary Supporting Facilitated Communication [texte imprimé] / Katharine BEALS, Auteur ; Bronwyn HEMSLEY, Auteur ; Russell LANG, Auteur ; Howard SHANE, Auteur . - p.e70258. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70258 Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.70258 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Why I Invited a Commentary on “Why We Need to Study Assisted Methods to Teach Typing to Nonspeaking Autistic People” / David G. AMARAL in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70259 Titre : Why I Invited a Commentary on “Why We Need to Study Assisted Methods to Teach Typing to Nonspeaking Autistic People” Type de document : texte imprimé Auteurs : David G. AMARAL, Auteur Article en page(s) : p.e70259 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.70259 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Why I Invited a Commentary on “Why We Need to Study Assisted Methods to Teach Typing to Nonspeaking Autistic People” [texte imprimé] / David G. AMARAL, Auteur . - p.e70259. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70259 Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.70259 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Empirical Validation Must Be a Precondition to Future Research in Facilitated Communication / Amy LUTZ in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70262 Titre : Empirical Validation Must Be a Precondition to Future Research in Facilitated Communication Type de document : texte imprimé Auteurs : Amy LUTZ, Auteur ; Jill ESCHER, Auteur ; Alycia HALLADAY, Auteur ; Alison SINGER, Auteur Article en page(s) : p.e70262 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.70262 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Empirical Validation Must Be a Precondition to Future Research in Facilitated Communication [texte imprimé] / Amy LUTZ, Auteur ; Jill ESCHER, Auteur ; Alycia HALLADAY, Auteur ; Alison SINGER, Auteur . - p.e70262. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70262 Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.70262 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Hope Is Not Enough: Assisted Typing Must Meet Scientific Standards / Connie KASARI in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70266 Titre : Hope Is Not Enough: Assisted Typing Must Meet Scientific Standards Type de document : texte imprimé Auteurs : Connie KASARI, Auteur Article en page(s) : p.e70266 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.70266 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Hope Is Not Enough: Assisted Typing Must Meet Scientific Standards [texte imprimé] / Connie KASARI, Auteur . - p.e70266. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70266 Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.70266 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587

Independent Typers Exist: A Reply to Letters on Why We Need to Study Assisted Methods to Teach Typing / Vikram K. JASWAL in Autism Research, 19-5 (May 2026)  

Public ISBD [article]  inAutism Research > 19-5 (May 2026) . - p.e70278 Titre : Independent Typers Exist: A Reply to Letters on Why We Need to Study Assisted Methods to Teach Typing Type de document : texte imprimé Auteurs : Vikram K. JASWAL, Auteur ; Barry M. PRIZANT, Auteur ; Morgan D. BARENSE, Auteur ; Kristie PATTEN, Auteur ; Gary STOBBE, Auteur Article en page(s) : p.e70278 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.70278 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 [article] Independent Typers Exist: A Reply to Letters on Why We Need to Study Assisted Methods to Teach Typing [texte imprimé] / Vikram K. JASWAL, Auteur ; Barry M. PRIZANT, Auteur ; Morgan D. BARENSE, Auteur ; Kristie PATTEN, Auteur ; Gary STOBBE, Auteur . - p.e70278. Langues : Anglais (eng) in Autism Research > 19-5 (May 2026) . - p.e70278 Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.70278 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587