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Genetic contributions to continuity and change in attachment security: a prospective, longitudinal investigation from infancy to young adulthood / K. LEE RABY in Journal of Child Psychology and Psychiatry, 54-11 (November 2013)
[article]
Titre : Genetic contributions to continuity and change in attachment security: a prospective, longitudinal investigation from infancy to young adulthood Type de document : Texte imprimé et/ou numérique Auteurs : K. LEE RABY, Auteur ; Dante CICCHETTI, Auteur ; Elizabeth A. CARLSON, Auteur ; Byron EGELAND, Auteur ; Andrew W. COLLINS, Auteur Article en page(s) : p.1223-1230 Langues : Anglais (eng) Mots-clés : Attachment continuity development genetics Index. décimale : PER Périodiques Résumé : Background Longitudinal research has demonstrated that individual differences in attachment security show only modest continuity from infancy to adulthood. Recent findings based on retrospective reports suggest that individuals' genetic variation may moderate the developmental associations between early attachment–relevant relationship experiences and adult attachment security. The purpose of this study was to use a prospective, longitudinal design to investigate genetic contributions to continuity and changes in attachment security from infancy to young adulthood in a higher risk sample. Methods Infant attachment security was assessed using the Strange Situation Procedure at 12 and 18 months. Adults' general attachment representations were assessed using the Adult Attachment Interview at ages 19 and 26. Romantic attachment representations were assessed with the Current Relationship Interview (CRI) at ages 20–21 and ages 26–28. Individuals were genotyped for variants within the oxytocin receptor (OXTR), dopamine D4 receptor (DRD4), and serotonin transporter linked polymorphic region (5-HTTLPR) . Results The continuity of attachment security from infancy into young adulthood was consistently moderated by OXTR genetic variation. Infant attachment security predicted the security of adults' general and romantic attachment representations only for individuals with the OXTR G/G genotype. This interaction was significant when predicting adult attachment security as measured by the Adult Attachment Interview at ages 19 and 26 and the CRI at ages 26–28. Dopamine D4 receptor and 5-HTTLPR genetic variation did not consistently moderate the longitudinal associations between attachment security during infancy and adulthood. Conclusions This study provides initial longitudinal evidence for genetic contributions to continuity and change in attachment security from infancy to young adulthood. Genetic variation related to the oxytocin system may moderate the stability of attachment security across development. En ligne : http://dx.doi.org/10.1111/jcpp.12093 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=217
in Journal of Child Psychology and Psychiatry > 54-11 (November 2013) . - p.1223-1230[article] Genetic contributions to continuity and change in attachment security: a prospective, longitudinal investigation from infancy to young adulthood [Texte imprimé et/ou numérique] / K. LEE RABY, Auteur ; Dante CICCHETTI, Auteur ; Elizabeth A. CARLSON, Auteur ; Byron EGELAND, Auteur ; Andrew W. COLLINS, Auteur . - p.1223-1230.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 54-11 (November 2013) . - p.1223-1230
Mots-clés : Attachment continuity development genetics Index. décimale : PER Périodiques Résumé : Background Longitudinal research has demonstrated that individual differences in attachment security show only modest continuity from infancy to adulthood. Recent findings based on retrospective reports suggest that individuals' genetic variation may moderate the developmental associations between early attachment–relevant relationship experiences and adult attachment security. The purpose of this study was to use a prospective, longitudinal design to investigate genetic contributions to continuity and changes in attachment security from infancy to young adulthood in a higher risk sample. Methods Infant attachment security was assessed using the Strange Situation Procedure at 12 and 18 months. Adults' general attachment representations were assessed using the Adult Attachment Interview at ages 19 and 26. Romantic attachment representations were assessed with the Current Relationship Interview (CRI) at ages 20–21 and ages 26–28. Individuals were genotyped for variants within the oxytocin receptor (OXTR), dopamine D4 receptor (DRD4), and serotonin transporter linked polymorphic region (5-HTTLPR) . Results The continuity of attachment security from infancy into young adulthood was consistently moderated by OXTR genetic variation. Infant attachment security predicted the security of adults' general and romantic attachment representations only for individuals with the OXTR G/G genotype. This interaction was significant when predicting adult attachment security as measured by the Adult Attachment Interview at ages 19 and 26 and the CRI at ages 26–28. Dopamine D4 receptor and 5-HTTLPR genetic variation did not consistently moderate the longitudinal associations between attachment security during infancy and adulthood. Conclusions This study provides initial longitudinal evidence for genetic contributions to continuity and change in attachment security from infancy to young adulthood. Genetic variation related to the oxytocin system may moderate the stability of attachment security across development. En ligne : http://dx.doi.org/10.1111/jcpp.12093 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=217 Homotypic and heterotypic continuity of symptoms of psychiatric disorders from age 4 to 10 years: a dynamic panel model / Lars WICHSTRØM in Journal of Child Psychology and Psychiatry, 58-11 (November 2017)
[article]
Titre : Homotypic and heterotypic continuity of symptoms of psychiatric disorders from age 4 to 10 years: a dynamic panel model Type de document : Texte imprimé et/ou numérique Auteurs : Lars WICHSTRØM, Auteur ; Jay BELSKY, Auteur ; Silje STEINSBEKK, Auteur Article en page(s) : p.1239-1247 Langues : Anglais (eng) Mots-clés : Attention-deficit/hyperactivity disorder anxiety conduct disorder continuity depression fixed effects heterotypic homotypic longitudinal life-events oppositional defiant disorder prospective psychiatric disorder symptoms Index. décimale : PER Périodiques Résumé : Background Childhood psychiatric disorders and their symptoms evince both within-disorder (homotypic) and between-disorder (heterotypic) continuities. These continuities may be due to earlier symptoms causing later symptoms or, alternatively, that the same (unknown) causes (e.g., genetics) are operating across time. Applying a novel data analytic approach, we disentangle these two explanations. Methods Participants in a Norwegian community study were assessed biennially from 4 to 10 years of age with clinical interviews (n = 1,042). Prospective reciprocal relations between symptoms of disorders were analyzed with a dynamic panel model within a structural equation framework, adjusting for all unmeasured time-invariant confounders and time-varying negative life-events. Results Homotypic continuities in symptoms characterized all disorders; strongest for attention-deficit/hyperactivity disorder (ADHD) (r = .32–.62), moderate for behavioral disorders (r = .31–.48) and for anxiety and depression (r = .15–.40), and stronger between 8 and 10 than between 4 and 6 years. Heterotypic continuity also characterized all disorders. A dynamic panel model showed that most continuities were due to unmeasured time-invariant factors rather than effects of earlier symptoms on later symptoms, although symptoms of behavioral disorders, which evinced two-year homotypic continuity (B = .14, 95% CI: .04, .25), did influence later symptoms of ADHD (B = .13, CI: .03, .23), and earlier ADHD symptoms influenced later anxiety disorder symptoms (B = .07, CI: .01, .12). Conclusions Homotypic and heterotypic continuities of symptoms of childhood psychiatric disorders are mostly due to unobserved time-invariant factors. Nonetheless, symptoms of earlier behavioral disorders may affect later symptoms of such disorders and of ADHD, and ADHD may increase the risk of later anxiety. Thus, even if interventions do not alter basic etiological factors, symptom reduction may itself cause later symptom reduction. En ligne : http://dx.doi.org/10.1111/jcpp.12754 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=326
in Journal of Child Psychology and Psychiatry > 58-11 (November 2017) . - p.1239-1247[article] Homotypic and heterotypic continuity of symptoms of psychiatric disorders from age 4 to 10 years: a dynamic panel model [Texte imprimé et/ou numérique] / Lars WICHSTRØM, Auteur ; Jay BELSKY, Auteur ; Silje STEINSBEKK, Auteur . - p.1239-1247.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 58-11 (November 2017) . - p.1239-1247
Mots-clés : Attention-deficit/hyperactivity disorder anxiety conduct disorder continuity depression fixed effects heterotypic homotypic longitudinal life-events oppositional defiant disorder prospective psychiatric disorder symptoms Index. décimale : PER Périodiques Résumé : Background Childhood psychiatric disorders and their symptoms evince both within-disorder (homotypic) and between-disorder (heterotypic) continuities. These continuities may be due to earlier symptoms causing later symptoms or, alternatively, that the same (unknown) causes (e.g., genetics) are operating across time. Applying a novel data analytic approach, we disentangle these two explanations. Methods Participants in a Norwegian community study were assessed biennially from 4 to 10 years of age with clinical interviews (n = 1,042). Prospective reciprocal relations between symptoms of disorders were analyzed with a dynamic panel model within a structural equation framework, adjusting for all unmeasured time-invariant confounders and time-varying negative life-events. Results Homotypic continuities in symptoms characterized all disorders; strongest for attention-deficit/hyperactivity disorder (ADHD) (r = .32–.62), moderate for behavioral disorders (r = .31–.48) and for anxiety and depression (r = .15–.40), and stronger between 8 and 10 than between 4 and 6 years. Heterotypic continuity also characterized all disorders. A dynamic panel model showed that most continuities were due to unmeasured time-invariant factors rather than effects of earlier symptoms on later symptoms, although symptoms of behavioral disorders, which evinced two-year homotypic continuity (B = .14, 95% CI: .04, .25), did influence later symptoms of ADHD (B = .13, CI: .03, .23), and earlier ADHD symptoms influenced later anxiety disorder symptoms (B = .07, CI: .01, .12). Conclusions Homotypic and heterotypic continuities of symptoms of childhood psychiatric disorders are mostly due to unobserved time-invariant factors. Nonetheless, symptoms of earlier behavioral disorders may affect later symptoms of such disorders and of ADHD, and ADHD may increase the risk of later anxiety. Thus, even if interventions do not alter basic etiological factors, symptom reduction may itself cause later symptom reduction. En ligne : http://dx.doi.org/10.1111/jcpp.12754 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=326 Developmental stability of general and specific factors of psychopathology from early childhood to adolescence: dynamic mutualism or p-differentiation? / E. MCELROY in Journal of Child Psychology and Psychiatry, 59-6 (June 2018)
[article]
Titre : Developmental stability of general and specific factors of psychopathology from early childhood to adolescence: dynamic mutualism or p-differentiation? Type de document : Texte imprimé et/ou numérique Auteurs : E. MCELROY, Auteur ; J. BELSKY, Auteur ; Natacha CARRAGHER, Auteur ; P. FEARON, Auteur ; Praveetha PATALAY, Auteur Article en page(s) : p.667-675 Langues : Anglais (eng) Mots-clés : Comorbidity continuity developmental psychopathology externalizing disorder internalizing disorder Index. décimale : PER Périodiques Résumé : BACKGROUND: Recent research indicates that the best-fitting structural model of psychopathology includes a general factor capturing comorbidity (p) and several more specific, orthogonal factors. Little is known about the stability of these factors, although two opposing developmental processes have been proposed: dynamic mutualism suggests that symptom-level interaction and reinforcement may lead to a strengthening of comorbidity (p) over time, whereas p-differentiation suggests a general vulnerability to psychopathology that gives way to increasingly distinct patterns of symptoms over time. In order to test both processes, we examine two forms of developmental stability from ages 2 to 14 years: strength (i.e., consistency in the amount of variance explained by general and specific factors) and phenotypic stability (i.e., homotypic and heterotypic continuity). METHODS: Data are from the NICHD Study of Early Child Care and Youth Development. Psychopathology symptoms were assessed nine times between ages 2 and 14 years (n = 1,253) using the Child Behavior Checklist completed by mothers. Confirmatory bifactor modeling was used to test structural models of psychopathology at each age. Consistency in strength was examined by calculating the Explained Common Variance (ECV) and phenotypic stability was investigated with cross-lagged modeling of the general and specific factors. RESULTS: Bifactor models fit the data well across this developmental period. ECV values were reasonably consistent across development, with the general factor accounting for the majority of shared variance (61%-71%). Evidence of both homotypic and heterotypic continuity emerged, with most heterotypic continuity involving the general factor, as it both predicted and was predicted by specific factors. CONCLUSIONS: A bifactor model effectively captures psychopathological comorbidity from early childhood through adolescence. The longitudinal associations between the general and specific factors provide evidence for both the hypothesized processes (dynamic mutualism and p-differentiation) occurring through development. En ligne : http://dx.doi.org/10.1111/jcpp.12849 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=363
in Journal of Child Psychology and Psychiatry > 59-6 (June 2018) . - p.667-675[article] Developmental stability of general and specific factors of psychopathology from early childhood to adolescence: dynamic mutualism or p-differentiation? [Texte imprimé et/ou numérique] / E. MCELROY, Auteur ; J. BELSKY, Auteur ; Natacha CARRAGHER, Auteur ; P. FEARON, Auteur ; Praveetha PATALAY, Auteur . - p.667-675.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 59-6 (June 2018) . - p.667-675
Mots-clés : Comorbidity continuity developmental psychopathology externalizing disorder internalizing disorder Index. décimale : PER Périodiques Résumé : BACKGROUND: Recent research indicates that the best-fitting structural model of psychopathology includes a general factor capturing comorbidity (p) and several more specific, orthogonal factors. Little is known about the stability of these factors, although two opposing developmental processes have been proposed: dynamic mutualism suggests that symptom-level interaction and reinforcement may lead to a strengthening of comorbidity (p) over time, whereas p-differentiation suggests a general vulnerability to psychopathology that gives way to increasingly distinct patterns of symptoms over time. In order to test both processes, we examine two forms of developmental stability from ages 2 to 14 years: strength (i.e., consistency in the amount of variance explained by general and specific factors) and phenotypic stability (i.e., homotypic and heterotypic continuity). METHODS: Data are from the NICHD Study of Early Child Care and Youth Development. Psychopathology symptoms were assessed nine times between ages 2 and 14 years (n = 1,253) using the Child Behavior Checklist completed by mothers. Confirmatory bifactor modeling was used to test structural models of psychopathology at each age. Consistency in strength was examined by calculating the Explained Common Variance (ECV) and phenotypic stability was investigated with cross-lagged modeling of the general and specific factors. RESULTS: Bifactor models fit the data well across this developmental period. ECV values were reasonably consistent across development, with the general factor accounting for the majority of shared variance (61%-71%). Evidence of both homotypic and heterotypic continuity emerged, with most heterotypic continuity involving the general factor, as it both predicted and was predicted by specific factors. CONCLUSIONS: A bifactor model effectively captures psychopathological comorbidity from early childhood through adolescence. The longitudinal associations between the general and specific factors provide evidence for both the hypothesized processes (dynamic mutualism and p-differentiation) occurring through development. En ligne : http://dx.doi.org/10.1111/jcpp.12849 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=363 Prevalence and course of anxiety disorders and symptoms from preschool to adolescence: a 6-wave community study / Silje STEINSBEKK in Journal of Child Psychology and Psychiatry, 63-5 (May 2022)
[article]
Titre : Prevalence and course of anxiety disorders and symptoms from preschool to adolescence: a 6-wave community study Type de document : Texte imprimé et/ou numérique Auteurs : Silje STEINSBEKK, Auteur ; Bror RANUM, Auteur ; Lars WICHSTRØM, Auteur Article en page(s) : p.527-534 Langues : Anglais (eng) Mots-clés : Adolescent Anxiety/epidemiology Anxiety Disorders/epidemiology Child Child, Preschool Humans Phobic Disorders/epidemiology Prevalence Anxiety continuity development longitudinal studies stability Index. décimale : PER Périodiques Résumé : BACKGROUND: The rate of various anxiety disorders in early childhood and whether they continue into middle childhood or adolescence is not known. We therefore report on the prevalence and stability of DSM-5-defined anxiety disorders and their symptoms, capturing the period from preschool to adolescence. METHODS: By means of interviewer-based clinical interviews, anxiety was measured in a sample of Norwegian children at six measurement points from age 4 to 14 (n=1,041). To adjust for time-invariant factors, we applied random intercept cross-lagged panel models (RI-CLPMs) capturing within-person changes. RESULTS: Nearly 10% (95% CI=7.29, 12.63) had an anxiety disorder at some timepoint. Specific phobia was the most prevalent disorder in early and middle childhood, whereas generalized anxiety disorder (GAD) increased in prevalence and became the most common anxiety disorder at age 14 (4.51%, 95% CI=2.78, 6.23). When time-invariant confounding was adjusted for, homotypic continuity in anxiety symptoms typically first emerged in late middle childhood or adolescence. Even so, such within-person analyses revealed a heterotypic path from increased number of early childhood symptoms of specific phobia to increased number of GAD symptoms in middle childhood (B=.41, 95% CI=.06, .75). Increased separation anxiety in middle childhood predicted increased symptoms of GAD in adolescence (B=.38, 95% CI=.14, .62), and vice versa (B=.05, 95% CI=.00, .09). Only minor gender differences were revealed. CONCLUSIONS: Anxiety disorders are prevalent in childhood. In early childhood, anxiety symptoms generally do not predict later anxiety symptoms. In middle childhood, however, such symptoms are less likely to vanish, indicating this developmental period to be particularly important for preventive and treatment efforts. En ligne : http://dx.doi.org/10.1111/jcpp.13487 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=476
in Journal of Child Psychology and Psychiatry > 63-5 (May 2022) . - p.527-534[article] Prevalence and course of anxiety disorders and symptoms from preschool to adolescence: a 6-wave community study [Texte imprimé et/ou numérique] / Silje STEINSBEKK, Auteur ; Bror RANUM, Auteur ; Lars WICHSTRØM, Auteur . - p.527-534.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 63-5 (May 2022) . - p.527-534
Mots-clés : Adolescent Anxiety/epidemiology Anxiety Disorders/epidemiology Child Child, Preschool Humans Phobic Disorders/epidemiology Prevalence Anxiety continuity development longitudinal studies stability Index. décimale : PER Périodiques Résumé : BACKGROUND: The rate of various anxiety disorders in early childhood and whether they continue into middle childhood or adolescence is not known. We therefore report on the prevalence and stability of DSM-5-defined anxiety disorders and their symptoms, capturing the period from preschool to adolescence. METHODS: By means of interviewer-based clinical interviews, anxiety was measured in a sample of Norwegian children at six measurement points from age 4 to 14 (n=1,041). To adjust for time-invariant factors, we applied random intercept cross-lagged panel models (RI-CLPMs) capturing within-person changes. RESULTS: Nearly 10% (95% CI=7.29, 12.63) had an anxiety disorder at some timepoint. Specific phobia was the most prevalent disorder in early and middle childhood, whereas generalized anxiety disorder (GAD) increased in prevalence and became the most common anxiety disorder at age 14 (4.51%, 95% CI=2.78, 6.23). When time-invariant confounding was adjusted for, homotypic continuity in anxiety symptoms typically first emerged in late middle childhood or adolescence. Even so, such within-person analyses revealed a heterotypic path from increased number of early childhood symptoms of specific phobia to increased number of GAD symptoms in middle childhood (B=.41, 95% CI=.06, .75). Increased separation anxiety in middle childhood predicted increased symptoms of GAD in adolescence (B=.38, 95% CI=.14, .62), and vice versa (B=.05, 95% CI=.00, .09). Only minor gender differences were revealed. CONCLUSIONS: Anxiety disorders are prevalent in childhood. In early childhood, anxiety symptoms generally do not predict later anxiety symptoms. In middle childhood, however, such symptoms are less likely to vanish, indicating this developmental period to be particularly important for preventive and treatment efforts. En ligne : http://dx.doi.org/10.1111/jcpp.13487 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=476 Depression from preschool to adolescence - five faces of stability / I. S. MORKEN in Journal of Child Psychology and Psychiatry, 62-8 (August 2021)
[article]
Titre : Depression from preschool to adolescence - five faces of stability Type de document : Texte imprimé et/ou numérique Auteurs : I. S. MORKEN, Auteur ; K. R. VIDDAL, Auteur ; B. RANUM, Auteur ; L. WICHSTRØM, Auteur Article en page(s) : p.1000-1009 Langues : Anglais (eng) Mots-clés : Adolescent Child Child, Preschool Depression Depressive Disorder, Major/epidemiology Family Humans Longitudinal Studies Parents Schools continuity developmental psychopathology etiology longitudinal Index. décimale : PER Périodiques Résumé : BACKGROUND: The term 'stability' has different meanings, and its implications for the etiology, prevention, and treatment of depression vary accordingly. Here, we identify five types of stability in childhood depression, many undetermined due to a lack of research or inconsistent findings. METHODS: Children and parents (n = 1,042) drawn from two birth cohorts in Trondheim, Norway, were followed biennially from ages 4-14 years. Symptoms of major depressive disorder (MDD) and dysthymia were assessed with the Preschool Age Psychiatric Assessment (only parents) and the Child and Adolescent Psychiatric Assessment (age 8 onwards). RESULTS: (a) Stability of form: Most symptoms increased in frequency. The symptoms' importance (according to factor loadings) was stable across childhood but increased from ages 12-14, indicating that MDD became more coherent. (b) Stability at the group level: The number of symptoms of dysthymia increased slightly until age 12, and the number of symptoms of MDD and dysthymia increased sharply between ages 12-14. (c) Stability relative to the group (i.e., 'rank-order') was modest to moderate and increased from ages 12-14. (d) Stability relative to oneself (i.e., intraclass correlations) was stronger than stability relative to the group and increased from age 12-14. (e) Stability of within-person changes: At all ages, decreases or increases in the number of symptoms forecasted similar changes two years later, but more strongly so between ages 12-14. CONCLUSIONS: Across childhood, while most symptoms of MDD and dysthymia become more frequent, they are equally important. The transition to adolescence is a particularly vulnerable period: The depression construct becomes more coherent, stability increases, the level of depression increases, and such an increase predicts further escalation. Even so, intervention at any time during childhood may have lasting effects on reducing child and adolescent depression. En ligne : http://dx.doi.org/10.1111/jcpp.13362 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456
in Journal of Child Psychology and Psychiatry > 62-8 (August 2021) . - p.1000-1009[article] Depression from preschool to adolescence - five faces of stability [Texte imprimé et/ou numérique] / I. S. MORKEN, Auteur ; K. R. VIDDAL, Auteur ; B. RANUM, Auteur ; L. WICHSTRØM, Auteur . - p.1000-1009.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 62-8 (August 2021) . - p.1000-1009
Mots-clés : Adolescent Child Child, Preschool Depression Depressive Disorder, Major/epidemiology Family Humans Longitudinal Studies Parents Schools continuity developmental psychopathology etiology longitudinal Index. décimale : PER Périodiques Résumé : BACKGROUND: The term 'stability' has different meanings, and its implications for the etiology, prevention, and treatment of depression vary accordingly. Here, we identify five types of stability in childhood depression, many undetermined due to a lack of research or inconsistent findings. METHODS: Children and parents (n = 1,042) drawn from two birth cohorts in Trondheim, Norway, were followed biennially from ages 4-14 years. Symptoms of major depressive disorder (MDD) and dysthymia were assessed with the Preschool Age Psychiatric Assessment (only parents) and the Child and Adolescent Psychiatric Assessment (age 8 onwards). RESULTS: (a) Stability of form: Most symptoms increased in frequency. The symptoms' importance (according to factor loadings) was stable across childhood but increased from ages 12-14, indicating that MDD became more coherent. (b) Stability at the group level: The number of symptoms of dysthymia increased slightly until age 12, and the number of symptoms of MDD and dysthymia increased sharply between ages 12-14. (c) Stability relative to the group (i.e., 'rank-order') was modest to moderate and increased from ages 12-14. (d) Stability relative to oneself (i.e., intraclass correlations) was stronger than stability relative to the group and increased from age 12-14. (e) Stability of within-person changes: At all ages, decreases or increases in the number of symptoms forecasted similar changes two years later, but more strongly so between ages 12-14. CONCLUSIONS: Across childhood, while most symptoms of MDD and dysthymia become more frequent, they are equally important. The transition to adolescence is a particularly vulnerable period: The depression construct becomes more coherent, stability increases, the level of depression increases, and such an increase predicts further escalation. Even so, intervention at any time during childhood may have lasting effects on reducing child and adolescent depression. En ligne : http://dx.doi.org/10.1111/jcpp.13362 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456 How much impairment is required for ADHD? No evidence of a discrete threshold / T. W. ARILDSKOV in Journal of Child Psychology and Psychiatry, 63-2 (February 2022)
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