Dépouillements

Incorporating self-advocacy and empowerment into small group therapy for adults on the autism spectrum: A pilot study / Grace M. DIGIOVANNI ; Elizabeth S. MCKEOWN ; Chandni K. SHAH ; Edward S. BRODKIN in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102425 Titre : Incorporating self-advocacy and empowerment into small group therapy for adults on the autism spectrum: A pilot study Type de document : Texte imprimé et/ou numérique Auteurs : Grace M. DIGIOVANNI, Auteur ; Elizabeth S. MCKEOWN, Auteur ; Chandni K. SHAH, Auteur ; Edward S. BRODKIN, Auteur Article en page(s) : p.102425 Langues : Anglais (eng) Mots-clés : Autism  Empowerment  Advocacy  Group therapy  Adults Index. décimale : PER Périodiques Résumé : Purpose Few programs exist which address the needs of autistic adults. Training to Understand and Navigate Emotions and Interactions (TUNE In), a 17-week cognitive-behavioral treatment program, was developed to support autistic adults by addressing social anxiety and motivation, social skills and cognition, and generalization of skills. The most recent iteration of TUNE In included a 4-session self-advocacy component which provided an opportunity to apply the skills learned from earlier parts of TUNE In. Methods As part of a novel program, Training to Understand and Navigate Emotions and Interactions (TUNE In), participants advocated for themselves and described their experiences to an audience of health care practitioners, researchers, and therapists who work with people on the autism spectrum. Of 18 participants who completed the TUNE In program, 15 participated in a qualitative interview, using a phenomenological approach, about their understanding of and receptivity to TUNE In, as well as its usefulness and utility in their daily lives. Results The majority of participants found benefit from the self-advocacy project component, with most participants indicating they felt empowered by the experience. Participants reported enjoyment and empowerment in presenting to the audiences, as the participants could express their interests, engage others in conversation, hear other autistic perspectives, and engage in dialogues about how psychological and medical treatments should change. Participants felt they were able to apply skills learned from earlier sessions of TUNE In throughout the advocacy presentations. Conclusion This study highlights that advocacy can be incorporated into treatment without sacrificing the goals of the treatment itself. Based on participant feedback, suggestions for program refinement, implications for social skills programs, and application of advocacy and empowerment to adult group therapies are discussed. En ligne : https://doi.org/10.1016/j.rasd.2024.102425 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] Incorporating self-advocacy and empowerment into small group therapy for adults on the autism spectrum: A pilot study [Texte imprimé et/ou numérique] / Grace M. DIGIOVANNI, Auteur ; Elizabeth S. MCKEOWN, Auteur ; Chandni K. SHAH, Auteur ; Edward S. BRODKIN, Auteur . - p.102425. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102425 Mots-clés : Autism  Empowerment  Advocacy  Group therapy  Adults Index. décimale : PER Périodiques Résumé : Purpose Few programs exist which address the needs of autistic adults. Training to Understand and Navigate Emotions and Interactions (TUNE In), a 17-week cognitive-behavioral treatment program, was developed to support autistic adults by addressing social anxiety and motivation, social skills and cognition, and generalization of skills. The most recent iteration of TUNE In included a 4-session self-advocacy component which provided an opportunity to apply the skills learned from earlier parts of TUNE In. Methods As part of a novel program, Training to Understand and Navigate Emotions and Interactions (TUNE In), participants advocated for themselves and described their experiences to an audience of health care practitioners, researchers, and therapists who work with people on the autism spectrum. Of 18 participants who completed the TUNE In program, 15 participated in a qualitative interview, using a phenomenological approach, about their understanding of and receptivity to TUNE In, as well as its usefulness and utility in their daily lives. Results The majority of participants found benefit from the self-advocacy project component, with most participants indicating they felt empowered by the experience. Participants reported enjoyment and empowerment in presenting to the audiences, as the participants could express their interests, engage others in conversation, hear other autistic perspectives, and engage in dialogues about how psychological and medical treatments should change. Participants felt they were able to apply skills learned from earlier sessions of TUNE In throughout the advocacy presentations. Conclusion This study highlights that advocacy can be incorporated into treatment without sacrificing the goals of the treatment itself. Based on participant feedback, suggestions for program refinement, implications for social skills programs, and application of advocacy and empowerment to adult group therapies are discussed. En ligne : https://doi.org/10.1016/j.rasd.2024.102425 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

The relationships between restrictive/repetitive behaviours, intolerance of uncertainty, and anxiety in autism: A systematic review and meta-analysis / Lucy Anne Elizabeth MOID ; Christopher A. JONES ; Andrew D. R. SURTEES in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102428 Titre : The relationships between restrictive/repetitive behaviours, intolerance of uncertainty, and anxiety in autism: A systematic review and meta-analysis Type de document : Texte imprimé et/ou numérique Auteurs : Lucy Anne Elizabeth MOID, Auteur ; Christopher A. JONES, Auteur ; Andrew D. R. SURTEES, Auteur Article en page(s) : p.102428 Langues : Anglais (eng) Mots-clés : Autism  ASD  Anxiety  Uncertainty  Repetitive Behaviour  Meta-analysis Index. décimale : PER Périodiques Résumé : Autistic people are more likely to experience anxiety than their non-autistic peers. Understanding mechanisms underpinning anxiety in autism is a vital aspect of developing effective interventions. Intolerance of uncertainty (IU) and restrictive/repetitive behaviours (RRBs) are proposed to contribute to anxiety for autistic people. This paper includes the first meta-analysis to investigate the associations between all three of these variables. A systematic search identified 33 papers that measured anxiety, IU and RRBs in 8347 autistic participants. Evidence was found for positive correlations between all three variables. Analysis of average participant age demonstrated that the relationship between anxiety and IU was stronger in younger participants. No significant differences were found between the associations in studies that included participants with intellectual disabilities and those that did not. A quality assessment framework identified methodological threats to validity. Most studies had good methods of recruitment; however, many anxiety and IU measurement tools were unvalidated in autistic populations. Results suggest that IU and RRBs should be considered when designing anxiety interventions for autistic people, however, the role of RRBs in particular needs to be investigated further to prevent interventions from taking away important coping strategies due to misunderstanding of causal relationships. En ligne : https://doi.org/10.1016/j.rasd.2024.102428 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] The relationships between restrictive/repetitive behaviours, intolerance of uncertainty, and anxiety in autism: A systematic review and meta-analysis [Texte imprimé et/ou numérique] / Lucy Anne Elizabeth MOID, Auteur ; Christopher A. JONES, Auteur ; Andrew D. R. SURTEES, Auteur . - p.102428. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102428 Mots-clés : Autism  ASD  Anxiety  Uncertainty  Repetitive Behaviour  Meta-analysis Index. décimale : PER Périodiques Résumé : Autistic people are more likely to experience anxiety than their non-autistic peers. Understanding mechanisms underpinning anxiety in autism is a vital aspect of developing effective interventions. Intolerance of uncertainty (IU) and restrictive/repetitive behaviours (RRBs) are proposed to contribute to anxiety for autistic people. This paper includes the first meta-analysis to investigate the associations between all three of these variables. A systematic search identified 33 papers that measured anxiety, IU and RRBs in 8347 autistic participants. Evidence was found for positive correlations between all three variables. Analysis of average participant age demonstrated that the relationship between anxiety and IU was stronger in younger participants. No significant differences were found between the associations in studies that included participants with intellectual disabilities and those that did not. A quality assessment framework identified methodological threats to validity. Most studies had good methods of recruitment; however, many anxiety and IU measurement tools were unvalidated in autistic populations. Results suggest that IU and RRBs should be considered when designing anxiety interventions for autistic people, however, the role of RRBs in particular needs to be investigated further to prevent interventions from taking away important coping strategies due to misunderstanding of causal relationships. En ligne : https://doi.org/10.1016/j.rasd.2024.102428 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

Perspectives of autistic students and their teachers on self-determination and peer support / Karrie A. SHOGREN ; LaRon SCOTT ; Delia KAN ; Barbara BOSSEN ; Kara HUME in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102438 Titre : Perspectives of autistic students and their teachers on self-determination and peer support Type de document : Texte imprimé et/ou numérique Auteurs : Karrie A. SHOGREN, Auteur ; LaRon SCOTT, Auteur ; Delia KAN, Auteur ; Barbara BOSSEN, Auteur ; Kara HUME, Auteur Article en page(s) : p.102438 Langues : Anglais (eng) Mots-clés : Self-determination  Peer support  Evidence-based interventions  Students with disabilities  Self-Determined Learning Model of Instruction  Autism  Social validity Index. décimale : PER Périodiques Résumé : Autistic students may need individualized supports to meet their academic, social, and self-determination needs in inclusive classrooms. However, few evidence-based interventions have been developed to provide these supports for autistic adolescents, and little is known about the perceptions of autistic youth about these interventions in use in high schools. This study aimed to explore the perspectives of autistic students and their teachers on self-determination and peer support, as well as their thoughts about two evidence-based interventions used in their classroom settings: the Self-Determined Learning Model of Instruction and Peer Supports. An overall theme of empowerment was identified from student and teacher data collected across the interventions, which highlighted the importance of enabling students to access these interventions in inclusive environments. Autistic students experienced growth in understanding their identity and role as students, peers, and learners, and many felt empowered to set and achieve goals important to their future success. Teachers noted increased self-confidence and assertiveness in students pursuing their goals, highlighting the need for inclusive interventions that address positive in-school and post-school outcomes for secondary autistic students. En ligne : https://doi.org/10.1016/j.rasd.2024.102438 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] Perspectives of autistic students and their teachers on self-determination and peer support [Texte imprimé et/ou numérique] / Karrie A. SHOGREN, Auteur ; LaRon SCOTT, Auteur ; Delia KAN, Auteur ; Barbara BOSSEN, Auteur ; Kara HUME, Auteur . - p.102438. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102438 Mots-clés : Self-determination  Peer support  Evidence-based interventions  Students with disabilities  Self-Determined Learning Model of Instruction  Autism  Social validity Index. décimale : PER Périodiques Résumé : Autistic students may need individualized supports to meet their academic, social, and self-determination needs in inclusive classrooms. However, few evidence-based interventions have been developed to provide these supports for autistic adolescents, and little is known about the perceptions of autistic youth about these interventions in use in high schools. This study aimed to explore the perspectives of autistic students and their teachers on self-determination and peer support, as well as their thoughts about two evidence-based interventions used in their classroom settings: the Self-Determined Learning Model of Instruction and Peer Supports. An overall theme of empowerment was identified from student and teacher data collected across the interventions, which highlighted the importance of enabling students to access these interventions in inclusive environments. Autistic students experienced growth in understanding their identity and role as students, peers, and learners, and many felt empowered to set and achieve goals important to their future success. Teachers noted increased self-confidence and assertiveness in students pursuing their goals, highlighting the need for inclusive interventions that address positive in-school and post-school outcomes for secondary autistic students. En ligne : https://doi.org/10.1016/j.rasd.2024.102438 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

Unique and enriched microbes and their potential "allies and foes" in the human gut microbiomes of ASD patients / Lianwei LI ; Hongju CHEN in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102440 Titre : Unique and enriched microbes and their potential "allies and foes" in the human gut microbiomes of ASD patients Type de document : Texte imprimé et/ou numérique Auteurs : Lianwei LI, Auteur ; Hongju CHEN, Auteur Article en page(s) : p.102440 Langues : Anglais (eng) Mots-clés : ASD (autism spectrum disorder)  Brain-gut-microbiome axis (BGM)  Unique species (US) associated with ASD  Enriched species (ES) associated with ASD  Species specificity (SS)  Specificity diversity (SD) Index. décimale : PER Périodiques Résumé : Studies with animal models and humans show that alternations in the composition and activity of the gut microbiome can contribute to the etiopathogenesis of core symptoms in the ASD (autism spectrum disorder) patients. The role has been investigated by extending classic brain-gut axis to brain-gut-microbiome (BGM) axis. Nevertheless, there is not yet a consensus regarding the compositional changes associated with ASD. Here we fill a gap by computationally detecting and compiling the lists of US (unique species) and ES (enriched species) associated with ASD from big datasets on ASD-microbiome studies. The gap is that different existing studies generated conflicting evidence regarding the ES/US status, and the existing ES/US lists often lack rigorous statistical quantifications, which is likely responsible for the inconsistencies. To fill the gap, we apply and extend a recent computational advance for virome comparison (VC) that statistical rigorously determines the US/ES status and their holistic differences between the diseased treatments and healthy controls. We further extend the VC approach by building the first-order (nearest neighbor) network (FON) of US/ES taxa to deepen our understanding of the microbes associated with ASD, including their allies and foes. We obtained the US/ES lists from 8 individual datasets separately and their pooled datasets with statistical rigor and computed their union/intersection sets to make recommendations for practical applications of US/ES catalogues. We also built the FON and revealed possibly general species occurrence patterns of US/ES in ASD patients, analyzed the extreme complexity in gut microbiome alternations associated with ASD. En ligne : https://doi.org/10.1016/j.rasd.2024.102440 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] Unique and enriched microbes and their potential "allies and foes" in the human gut microbiomes of ASD patients [Texte imprimé et/ou numérique] / Lianwei LI, Auteur ; Hongju CHEN, Auteur . - p.102440. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102440 Mots-clés : ASD (autism spectrum disorder)  Brain-gut-microbiome axis (BGM)  Unique species (US) associated with ASD  Enriched species (ES) associated with ASD  Species specificity (SS)  Specificity diversity (SD) Index. décimale : PER Périodiques Résumé : Studies with animal models and humans show that alternations in the composition and activity of the gut microbiome can contribute to the etiopathogenesis of core symptoms in the ASD (autism spectrum disorder) patients. The role has been investigated by extending classic brain-gut axis to brain-gut-microbiome (BGM) axis. Nevertheless, there is not yet a consensus regarding the compositional changes associated with ASD. Here we fill a gap by computationally detecting and compiling the lists of US (unique species) and ES (enriched species) associated with ASD from big datasets on ASD-microbiome studies. The gap is that different existing studies generated conflicting evidence regarding the ES/US status, and the existing ES/US lists often lack rigorous statistical quantifications, which is likely responsible for the inconsistencies. To fill the gap, we apply and extend a recent computational advance for virome comparison (VC) that statistical rigorously determines the US/ES status and their holistic differences between the diseased treatments and healthy controls. We further extend the VC approach by building the first-order (nearest neighbor) network (FON) of US/ES taxa to deepen our understanding of the microbes associated with ASD, including their allies and foes. We obtained the US/ES lists from 8 individual datasets separately and their pooled datasets with statistical rigor and computed their union/intersection sets to make recommendations for practical applications of US/ES catalogues. We also built the FON and revealed possibly general species occurrence patterns of US/ES in ASD patients, analyzed the extreme complexity in gut microbiome alternations associated with ASD. En ligne : https://doi.org/10.1016/j.rasd.2024.102440 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

"Education would be step number one": Community mental health clinicians'training and support needs to treat anxiety in autistic youth / Grace Lee SIMMONS ; Julia HEINLY ; Daylin DELGADO ; Whitney S. SHEPHERD ; Lauren BROOKMAN-FRAZEE ; Eric A. STORCH ; Brenna B. MADDOX in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102450 Titre : "Education would be step number one": Community mental health clinicians'training and support needs to treat anxiety in autistic youth Type de document : Texte imprimé et/ou numérique Auteurs : Grace Lee SIMMONS, Auteur ; Julia HEINLY, Auteur ; Daylin DELGADO, Auteur ; Whitney S. SHEPHERD, Auteur ; Lauren BROOKMAN-FRAZEE, Auteur ; Eric A. STORCH, Auteur ; Brenna B. MADDOX, Auteur Article en page(s) : p.102450 Langues : Anglais (eng) Mots-clés : Mental health  Community  Training  Autism  Anxiety Index. décimale : PER Périodiques Résumé : Background Autistic youth experience high rates of anxiety, which has been treated with modified cognitive-behavioral therapy (CBT), often integrating exposure therapy. Such anxiety treatments are effective for this population; however, there remains a gap between these evidence-based mental health interventions and their implementation in community mental health (CMH) services where autistic youth receive care. Method This qualitative study conducted semi-structured interviews with four types of community members in the United States: 15 autistic youth with anxiety, 15 caregivers of autistic youth with anxiety, 11 CMH clinicians, and 8 CMH clinic leaders. Participants identified the training needs of CMH clinicians to support the delivery of CBT for autistic youth with anxiety. Results Through inductive thematic analysis, three themes were found: presentation of autism and anxiety, intervention delivery, and training format. Participants highlighted the need for clinician education to understand the varying presentations of autism and co-occurring anxiety and how to effectively deliver a personalized mental health intervention for autistic youth. Clinicians also desired a clinician training program that includes engaging components and offers individualized, ongoing support while the intervention is delivered. Conclusions Findings from this study will inform the development of a clinician training program to deliver CBT modified for autistic youth with anxiety in CMH contexts. En ligne : https://doi.org/10.1016/j.rasd.2024.102450 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] "Education would be step number one": Community mental health clinicians'training and support needs to treat anxiety in autistic youth [Texte imprimé et/ou numérique] / Grace Lee SIMMONS, Auteur ; Julia HEINLY, Auteur ; Daylin DELGADO, Auteur ; Whitney S. SHEPHERD, Auteur ; Lauren BROOKMAN-FRAZEE, Auteur ; Eric A. STORCH, Auteur ; Brenna B. MADDOX, Auteur . - p.102450. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102450 Mots-clés : Mental health  Community  Training  Autism  Anxiety Index. décimale : PER Périodiques Résumé : Background Autistic youth experience high rates of anxiety, which has been treated with modified cognitive-behavioral therapy (CBT), often integrating exposure therapy. Such anxiety treatments are effective for this population; however, there remains a gap between these evidence-based mental health interventions and their implementation in community mental health (CMH) services where autistic youth receive care. Method This qualitative study conducted semi-structured interviews with four types of community members in the United States: 15 autistic youth with anxiety, 15 caregivers of autistic youth with anxiety, 11 CMH clinicians, and 8 CMH clinic leaders. Participants identified the training needs of CMH clinicians to support the delivery of CBT for autistic youth with anxiety. Results Through inductive thematic analysis, three themes were found: presentation of autism and anxiety, intervention delivery, and training format. Participants highlighted the need for clinician education to understand the varying presentations of autism and co-occurring anxiety and how to effectively deliver a personalized mental health intervention for autistic youth. Clinicians also desired a clinician training program that includes engaging components and offers individualized, ongoing support while the intervention is delivered. Conclusions Findings from this study will inform the development of a clinician training program to deliver CBT modified for autistic youth with anxiety in CMH contexts. En ligne : https://doi.org/10.1016/j.rasd.2024.102450 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

Development of a standardized set of outcomes for autism spectrum disorder: The International Consortium for Health Outcomes Measurement (ICHOM) / Ivy CHONG ; Zofia DAS-GUPTA ; Claudia Bandeira DE LIMA ; Dennis DIXON ; Svyatoslav DOVBNYA ; Ellen FITTRO ; Peter GERHARDT ; Weihe HUANG ; Braden JOSEPHSON ; DAN LI ; Neil MARTIN ; Shaneel MUKERJI ; Kristine RODRIGUEZ ; Hanna RUE ; Kim STRUNK ; Jonathan TARBOX ; Yagnesh VADGAMA ; Amber VALENTINO ; Javier VIRUES-ORTEGA ; Sandra WILLIS in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102451 Titre : Development of a standardized set of outcomes for autism spectrum disorder: The International Consortium for Health Outcomes Measurement (ICHOM) Type de document : Texte imprimé et/ou numérique Auteurs : Ivy CHONG, Auteur ; Zofia DAS-GUPTA, Auteur ; Claudia Bandeira DE LIMA, Auteur ; Dennis DIXON, Auteur ; Svyatoslav DOVBNYA, Auteur ; Ellen FITTRO, Auteur ; Peter GERHARDT, Auteur ; Weihe HUANG, Auteur ; Braden JOSEPHSON, Auteur ; DAN LI, Auteur ; Neil MARTIN, Auteur ; Shaneel MUKERJI, Auteur ; Kristine RODRIGUEZ, Auteur ; Hanna RUE, Auteur ; Kim STRUNK, Auteur ; Jonathan TARBOX, Auteur ; Yagnesh VADGAMA, Auteur ; Amber VALENTINO, Auteur ; Javier VIRUES-ORTEGA, Auteur ; Sandra WILLIS, Auteur Article en page(s) : p.102451 Langues : Anglais (eng) Mots-clés : ASD  Outcomes  Social communication  Repetitive behaviors Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder (ASD) is characterized by persistent deficits in reciprocal social interaction, communication, and restricted, repetitive, behaviour, that are atypical or excessive for the individual?s age and sociocultural context (Diagnostic and Statistical Manual 5th ed TR.; 2022). The rate of ASD continues to increase and remains a concern due to inequitable access to diagnosis and quality services. A lack of standardization in assessment and treatment presents further difficulty in benchmarking and improving care. Method The International Consortium for Health Outcomes Measurement (ICHOM) recruited a Working Group (WG) of 20 subject matter experts, including researchers, clinicians, policy makers, and lived-experience experts to identify a minimum set of measurable outcomes along with case mix variables (i.e., risk adjustment factors). A proposed set of Patient Centered Outcome Measures (henceforth known as the ASD Set) was identified and endorsed using a modified Delphi process to reach consensus. Results The WG took into consideration variation in global health, social care and educational systems were considered to ensure implementation of the ASD Set is feasible. The Set includes a core set of measurable outcomes (i.e., domains) that include core symptoms, daily functioning, accessibility, and support. Conclusions The ICHOM ASD Set is a scientifically-sound, internationally vetted tool that will enable assessment of care for individuals with ASD that can facilitate targeted, person-centered clinical and social inclusion strategies. Large scale implementation and use should generate standardized data describing the individual's health and wellbeing that can inform decision-making, quality improvement and best-practices insights. En ligne : https://doi.org/10.1016/j.rasd.2024.102451 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] Development of a standardized set of outcomes for autism spectrum disorder: The International Consortium for Health Outcomes Measurement (ICHOM) [Texte imprimé et/ou numérique] / Ivy CHONG, Auteur ; Zofia DAS-GUPTA, Auteur ; Claudia Bandeira DE LIMA, Auteur ; Dennis DIXON, Auteur ; Svyatoslav DOVBNYA, Auteur ; Ellen FITTRO, Auteur ; Peter GERHARDT, Auteur ; Weihe HUANG, Auteur ; Braden JOSEPHSON, Auteur ; DAN LI, Auteur ; Neil MARTIN, Auteur ; Shaneel MUKERJI, Auteur ; Kristine RODRIGUEZ, Auteur ; Hanna RUE, Auteur ; Kim STRUNK, Auteur ; Jonathan TARBOX, Auteur ; Yagnesh VADGAMA, Auteur ; Amber VALENTINO, Auteur ; Javier VIRUES-ORTEGA, Auteur ; Sandra WILLIS, Auteur . - p.102451. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102451 Mots-clés : ASD  Outcomes  Social communication  Repetitive behaviors Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder (ASD) is characterized by persistent deficits in reciprocal social interaction, communication, and restricted, repetitive, behaviour, that are atypical or excessive for the individual?s age and sociocultural context (Diagnostic and Statistical Manual 5th ed TR.; 2022). The rate of ASD continues to increase and remains a concern due to inequitable access to diagnosis and quality services. A lack of standardization in assessment and treatment presents further difficulty in benchmarking and improving care. Method The International Consortium for Health Outcomes Measurement (ICHOM) recruited a Working Group (WG) of 20 subject matter experts, including researchers, clinicians, policy makers, and lived-experience experts to identify a minimum set of measurable outcomes along with case mix variables (i.e., risk adjustment factors). A proposed set of Patient Centered Outcome Measures (henceforth known as the ASD Set) was identified and endorsed using a modified Delphi process to reach consensus. Results The WG took into consideration variation in global health, social care and educational systems were considered to ensure implementation of the ASD Set is feasible. The Set includes a core set of measurable outcomes (i.e., domains) that include core symptoms, daily functioning, accessibility, and support. Conclusions The ICHOM ASD Set is a scientifically-sound, internationally vetted tool that will enable assessment of care for individuals with ASD that can facilitate targeted, person-centered clinical and social inclusion strategies. Large scale implementation and use should generate standardized data describing the individual's health and wellbeing that can inform decision-making, quality improvement and best-practices insights. En ligne : https://doi.org/10.1016/j.rasd.2024.102451 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

Joint attention and maternal attention across varying dyadic interactions for autistic children / Laudan B. JAHROMI ; Marla R. BRASSARD ; Douglas GREER in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102452 Titre : Joint attention and maternal attention across varying dyadic interactions for autistic children Type de document : Texte imprimé et/ou numérique Auteurs : Laudan B. JAHROMI, Auteur ; Marla R. BRASSARD, Auteur ; Douglas GREER, Auteur Article en page(s) : p.102452 Langues : Anglais (eng) Mots-clés : Autism  ASD  Engagement  Joint attention  Social attention  Social communication Index. décimale : PER Périodiques Résumé : Background Joint attention (JA) is an area of delay associated with autism. Individual differences in JA are shown to relate to language development. The present study examined JA initiations (IJA) and responses to JA (RJA) of autistic children in structured and unstructured contexts with their mothers to examine the relation between mother attention and JA. Method Forty-two autistic children (ages 2.5 to 5.5 years) and their mothers engaged in 15 m interactions in three social contexts (competing demands, teaching, free play). Children were categorized by language level into limited language (N = 20) and verbal (N = 21) groups based on ADOS-2 module to assess group and contextual differences. Contingency analyses assessed bi-directional temporal relations between observed child JA and mother attention in lagged intervals. Results Rate of children?s IJA and maternal attention differed depending on the context of their interaction. Child IJA and mother attention showed a bi-directional temporally contingent association such that child IJA predicted subsequent maternal attention, and maternal attention predicted subsequent child IJA. RJA was unrelated to maternal attention in contingency analyses. Post-hoc analyses indicated a language level group by receptive communication, and group by expressive communication interaction on the contingency between child IJA and subsequent mother attention such that a stronger contingency emerged for dyads wherein children had limited language. Conclusions The present study illustrates the important role that children?s social communication behaviors may have within mother-child social interactions, and how children?s verbal ability, as well as the context of the social interaction may influence bi-directional social attention. En ligne : https://doi.org/10.1016/j.rasd.2024.102452 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] Joint attention and maternal attention across varying dyadic interactions for autistic children [Texte imprimé et/ou numérique] / Laudan B. JAHROMI, Auteur ; Marla R. BRASSARD, Auteur ; Douglas GREER, Auteur . - p.102452. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102452 Mots-clés : Autism  ASD  Engagement  Joint attention  Social attention  Social communication Index. décimale : PER Périodiques Résumé : Background Joint attention (JA) is an area of delay associated with autism. Individual differences in JA are shown to relate to language development. The present study examined JA initiations (IJA) and responses to JA (RJA) of autistic children in structured and unstructured contexts with their mothers to examine the relation between mother attention and JA. Method Forty-two autistic children (ages 2.5 to 5.5 years) and their mothers engaged in 15 m interactions in three social contexts (competing demands, teaching, free play). Children were categorized by language level into limited language (N = 20) and verbal (N = 21) groups based on ADOS-2 module to assess group and contextual differences. Contingency analyses assessed bi-directional temporal relations between observed child JA and mother attention in lagged intervals. Results Rate of children?s IJA and maternal attention differed depending on the context of their interaction. Child IJA and mother attention showed a bi-directional temporally contingent association such that child IJA predicted subsequent maternal attention, and maternal attention predicted subsequent child IJA. RJA was unrelated to maternal attention in contingency analyses. Post-hoc analyses indicated a language level group by receptive communication, and group by expressive communication interaction on the contingency between child IJA and subsequent mother attention such that a stronger contingency emerged for dyads wherein children had limited language. Conclusions The present study illustrates the important role that children?s social communication behaviors may have within mother-child social interactions, and how children?s verbal ability, as well as the context of the social interaction may influence bi-directional social attention. En ligne : https://doi.org/10.1016/j.rasd.2024.102452 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

CAVE automatic virtual environment technology to enhance social participation of autistic people: A classification and literature review / Vitor MATIAS ; William DE PAULA FERREIRA in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102453 Titre : CAVE automatic virtual environment technology to enhance social participation of autistic people: A classification and literature review Type de document : Texte imprimé et/ou numérique Auteurs : Vitor MATIAS, Auteur ; William DE PAULA FERREIRA, Auteur Article en page(s) : p.102453 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder  CAVE Automatic Virtual Environment  Blue room  Magic room  Immersive room  Virtual Reality  Social skills  Social participation  Immersive inclusive leisure Index. décimale : PER Périodiques Résumé : CAVE technology enables multi-participant experiences without head-mounted displays, accommodating the sensory sensitivities of autistic people and helping to enhance their social participation in the community. To date, recent studies have primarily identified therapeutic uses, without focusing on the technology?s recreational applications. To address this gap in the literature, our study aims to explore how CAVE technology can support the social participation of autistic people. This study was developed following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA 2020) protocol to ensure a robust and rigorous SLR. Results show 1) That there are different types of CAVE technology with numerous potential benefits for autistic people multi-participant engagement, sensory comfort, and customizable learning; 2) That CAVE technologies can enable the development of different social skills distinguishing personal emotions or understanding the intentions of others and adapting to the context. 3) Cost, technical complexity, space requirement, mobility, and learning curve are some of the barriers preventing this technology from being widely used in community or school organizations. In conclusion, this study suggests that CAVE technology can enhance social skills in autistic people and holds promise for innovative and inclusive leisure pursuits tailored for autism inclusion. En ligne : https://doi.org/10.1016/j.rasd.2024.102453 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] CAVE automatic virtual environment technology to enhance social participation of autistic people: A classification and literature review [Texte imprimé et/ou numérique] / Vitor MATIAS, Auteur ; William DE PAULA FERREIRA, Auteur . - p.102453. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102453 Mots-clés : Autism Spectrum Disorder  CAVE Automatic Virtual Environment  Blue room  Magic room  Immersive room  Virtual Reality  Social skills  Social participation  Immersive inclusive leisure Index. décimale : PER Périodiques Résumé : CAVE technology enables multi-participant experiences without head-mounted displays, accommodating the sensory sensitivities of autistic people and helping to enhance their social participation in the community. To date, recent studies have primarily identified therapeutic uses, without focusing on the technology?s recreational applications. To address this gap in the literature, our study aims to explore how CAVE technology can support the social participation of autistic people. This study was developed following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA 2020) protocol to ensure a robust and rigorous SLR. Results show 1) That there are different types of CAVE technology with numerous potential benefits for autistic people multi-participant engagement, sensory comfort, and customizable learning; 2) That CAVE technologies can enable the development of different social skills distinguishing personal emotions or understanding the intentions of others and adapting to the context. 3) Cost, technical complexity, space requirement, mobility, and learning curve are some of the barriers preventing this technology from being widely used in community or school organizations. In conclusion, this study suggests that CAVE technology can enhance social skills in autistic people and holds promise for innovative and inclusive leisure pursuits tailored for autism inclusion. En ligne : https://doi.org/10.1016/j.rasd.2024.102453 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

Reliability and validity of the Polish version of Communication and Symbolic Behaviour Scales-Developmental Profile - Infant-Toddler Checklist / Sylwia WRONA ; Maria FLAKUS ; Kamila PIERCHA?A ; Aleksandra SOBIESKA ; Katarzyna PODGÓRSKA ; Anna WO?OWICZ ; Ma?gorzata SEKU?OWICZ ; Maria Magdalena BUJNOWSKA-FEDAK in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102454 Titre : Reliability and validity of the Polish version of Communication and Symbolic Behaviour Scales-Developmental Profile - Infant-Toddler Checklist Type de document : Texte imprimé et/ou numérique Auteurs : Sylwia WRONA, Auteur ; Maria FLAKUS, Auteur ; Kamila PIERCHA?A, Auteur ; Aleksandra SOBIESKA, Auteur ; Katarzyna PODGÓRSKA, Auteur ; Anna WO?OWICZ, Auteur ; Ma?gorzata SEKU?OWICZ, Auteur ; Maria Magdalena BUJNOWSKA-FEDAK, Auteur Article en page(s) : p.102454 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Diagnostic screening programs  Primary health care  Validation study  Early diagnosis Index. décimale : PER Périodiques Résumé : Background Early diagnosis of autism spectrum disorders allows to start a therapy tailored to the child - the earlier it happens, the better the results. This study marked a preliminary attempt to prepare culturally and linguistically adapted Polish version of the Communication and Symbolic Behavior Scales-Developmental Profile - Infant-Toddler Checklist (CSBS-DP ITC). Method The study was conducted among 1471 Polish parents of children from the general population aged 6 to 24 months, 490 of them participated in the follow-up. An additional 122 pairs of parents completed the questionnaire to determine reliability using the inter-rater method. The collected data were statistically processed to calculate the reliability and validity of the Polish version of the CSBS-DP ITC questionnaire. Results The results indicated a very good fit of the one-factor and three-factor models in confirmatory factor analysis. Both one-factor and three-factor model showed satisfactory fit in both sex subsamples. The total score of CSBS-DP ITC demonstrated satisfactory internal consistency, Cronbach's ? = .92 and McDonald?s ? = .92. In test-retest all the correlation coefficients between the first and second measurements were above.70, proving a satisfactory level of stability. Conclusions The Polish version of the CSBS-DP-ITC is a reliable tool for the early screening of autism spectrum disorder, but further studies on sensitivity and specificity are essential. En ligne : https://doi.org/10.1016/j.rasd.2024.102454 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] Reliability and validity of the Polish version of Communication and Symbolic Behaviour Scales-Developmental Profile - Infant-Toddler Checklist [Texte imprimé et/ou numérique] / Sylwia WRONA, Auteur ; Maria FLAKUS, Auteur ; Kamila PIERCHA?A, Auteur ; Aleksandra SOBIESKA, Auteur ; Katarzyna PODGÓRSKA, Auteur ; Anna WO?OWICZ, Auteur ; Ma?gorzata SEKU?OWICZ, Auteur ; Maria Magdalena BUJNOWSKA-FEDAK, Auteur . - p.102454. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102454 Mots-clés : Autism spectrum disorder  Diagnostic screening programs  Primary health care  Validation study  Early diagnosis Index. décimale : PER Périodiques Résumé : Background Early diagnosis of autism spectrum disorders allows to start a therapy tailored to the child - the earlier it happens, the better the results. This study marked a preliminary attempt to prepare culturally and linguistically adapted Polish version of the Communication and Symbolic Behavior Scales-Developmental Profile - Infant-Toddler Checklist (CSBS-DP ITC). Method The study was conducted among 1471 Polish parents of children from the general population aged 6 to 24 months, 490 of them participated in the follow-up. An additional 122 pairs of parents completed the questionnaire to determine reliability using the inter-rater method. The collected data were statistically processed to calculate the reliability and validity of the Polish version of the CSBS-DP ITC questionnaire. Results The results indicated a very good fit of the one-factor and three-factor models in confirmatory factor analysis. Both one-factor and three-factor model showed satisfactory fit in both sex subsamples. The total score of CSBS-DP ITC demonstrated satisfactory internal consistency, Cronbach's ? = .92 and McDonald?s ? = .92. In test-retest all the correlation coefficients between the first and second measurements were above.70, proving a satisfactory level of stability. Conclusions The Polish version of the CSBS-DP-ITC is a reliable tool for the early screening of autism spectrum disorder, but further studies on sensitivity and specificity are essential. En ligne : https://doi.org/10.1016/j.rasd.2024.102454 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

Negotiating good motherhood: Lived experiences of mothers of children with autism spectrum disorder in China / Jialiang CUI in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102455 Titre : Negotiating good motherhood: Lived experiences of mothers of children with autism spectrum disorder in China Type de document : Texte imprimé et/ou numérique Auteurs : Jialiang CUI, Auteur Article en page(s) : p.102455 Langues : Anglais (eng) Mots-clés : Good motherhood  Mothering experience  Agency  China Index. décimale : PER Périodiques Résumé : Background Understanding how mothers negotiate the expectations of good motherhood ideology is vital for supporting mothers of children with ASD. This paper explored how Chinese mothers of children with ASD constructed the concept of good motherhood, and how this construct was formed, resisted and negotiated in the reality of caregiving. Method In-depth interviews were conducted with 21 mothers, revealing three major themes: (1) negotiating the role expectation of a super mother; (2) negotiating the emotional expectation of a rational mother; and (3) negotiating the moral expectation of a selfless mother. Results Findings indicate that when caring for children with ASD, mothers were expected to assume multiple roles responsibilities, perform emotion work and sacrifice their own needs to become good mothers. Instead of simply conforming to the good motherhood ideology, mothers employed various strategies to reflect on and even resist these expectations. Through these efforts, mothers actively constructed their own perceptions of good mothering based on their individual experiences, contributing to diverse knowledge of motherhood. Conclusions The findings underscore the importance of future support services to acknowledge the agency of mothers of children with ASD and utilize empowering approaches to accommodate their comprehensive needs. En ligne : https://doi.org/10.1016/j.rasd.2024.102455 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] Negotiating good motherhood: Lived experiences of mothers of children with autism spectrum disorder in China [Texte imprimé et/ou numérique] / Jialiang CUI, Auteur . - p.102455. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102455 Mots-clés : Good motherhood  Mothering experience  Agency  China Index. décimale : PER Périodiques Résumé : Background Understanding how mothers negotiate the expectations of good motherhood ideology is vital for supporting mothers of children with ASD. This paper explored how Chinese mothers of children with ASD constructed the concept of good motherhood, and how this construct was formed, resisted and negotiated in the reality of caregiving. Method In-depth interviews were conducted with 21 mothers, revealing three major themes: (1) negotiating the role expectation of a super mother; (2) negotiating the emotional expectation of a rational mother; and (3) negotiating the moral expectation of a selfless mother. Results Findings indicate that when caring for children with ASD, mothers were expected to assume multiple roles responsibilities, perform emotion work and sacrifice their own needs to become good mothers. Instead of simply conforming to the good motherhood ideology, mothers employed various strategies to reflect on and even resist these expectations. Through these efforts, mothers actively constructed their own perceptions of good mothering based on their individual experiences, contributing to diverse knowledge of motherhood. Conclusions The findings underscore the importance of future support services to acknowledge the agency of mothers of children with ASD and utilize empowering approaches to accommodate their comprehensive needs. En ligne : https://doi.org/10.1016/j.rasd.2024.102455 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

Telehealth-delivered behavioral sleep interventions for Autistic children: An evaluation of an enhanced stepped-care approach / Laurie MCLAY ; Karyn FRANCE ; Neville BLAMPIED in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102456 Titre : Telehealth-delivered behavioral sleep interventions for Autistic children: An evaluation of an enhanced stepped-care approach Type de document : Texte imprimé et/ou numérique Auteurs : Laurie MCLAY, Auteur ; Karyn FRANCE, Auteur ; Neville BLAMPIED, Auteur Article en page(s) : p.102456 Langues : Anglais (eng) Mots-clés : Telemedicine  Telehealth  Child  Autism  Sleep initiation and maintenance problems  Intervention Index. décimale : PER Périodiques Résumé : Background Sleep problems are common among Autistic children and can have adverse effects on their development, well-being and quality of life. Telehealth offers a cost-effective and accessible model of delivering evidence-based sleep support. This study used a single-case design to evaluate the efficacy of telehealth-delivered behavioral sleep intervention (TDBSI), with intervention phases designed based according to a stepped-care approach. Method Fourteen Autistic children (3-17 years) and their parents participated in a 12-week program consisting of three sequential intervention phases: 1) self-directed online parent education supplemented with individualized intervention tip sheets, 2) group parent coaching via video conferencing, and 3) individualized parent coaching via video conferencing. The appropriateness of parent strategy selection and implementation fidelity was rated throughout. Sleep problem severity (SPS) scores are reported for each child as a measure of effect across intervention phases. The Children's Sleep Habits Questionnaire (CSHQ) and CSHQ-Autism are reported as measures of change from baseline to post-intervention. Results Online parent education and tip sheets facilitated early success in parent strategy selection and implementation fidelity. SPS scores demonstrated large and statistically significant improvements in child sleep following the self-directed phase. Parent implementation fidelity and child sleep outcomes were further improved with group and individualized coaching. Post-intervention, the CSHQ and CSHQ-Autism revealed large and statistically significant improvements across subscales and participants compared to baseline. Conclusions Online parent education supplemented with individualized tip sheets demonstrates potential for addressing sleep problems in Autistic children. Therapist-led group and individualized parent coaching via videoconferencing show promise as higher intensity support for parents who do not achieve satisfactory results initially. En ligne : https://doi.org/10.1016/j.rasd.2024.102456 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] Telehealth-delivered behavioral sleep interventions for Autistic children: An evaluation of an enhanced stepped-care approach [Texte imprimé et/ou numérique] / Laurie MCLAY, Auteur ; Karyn FRANCE, Auteur ; Neville BLAMPIED, Auteur . - p.102456. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102456 Mots-clés : Telemedicine  Telehealth  Child  Autism  Sleep initiation and maintenance problems  Intervention Index. décimale : PER Périodiques Résumé : Background Sleep problems are common among Autistic children and can have adverse effects on their development, well-being and quality of life. Telehealth offers a cost-effective and accessible model of delivering evidence-based sleep support. This study used a single-case design to evaluate the efficacy of telehealth-delivered behavioral sleep intervention (TDBSI), with intervention phases designed based according to a stepped-care approach. Method Fourteen Autistic children (3-17 years) and their parents participated in a 12-week program consisting of three sequential intervention phases: 1) self-directed online parent education supplemented with individualized intervention tip sheets, 2) group parent coaching via video conferencing, and 3) individualized parent coaching via video conferencing. The appropriateness of parent strategy selection and implementation fidelity was rated throughout. Sleep problem severity (SPS) scores are reported for each child as a measure of effect across intervention phases. The Children's Sleep Habits Questionnaire (CSHQ) and CSHQ-Autism are reported as measures of change from baseline to post-intervention. Results Online parent education and tip sheets facilitated early success in parent strategy selection and implementation fidelity. SPS scores demonstrated large and statistically significant improvements in child sleep following the self-directed phase. Parent implementation fidelity and child sleep outcomes were further improved with group and individualized coaching. Post-intervention, the CSHQ and CSHQ-Autism revealed large and statistically significant improvements across subscales and participants compared to baseline. Conclusions Online parent education supplemented with individualized tip sheets demonstrates potential for addressing sleep problems in Autistic children. Therapist-led group and individualized parent coaching via videoconferencing show promise as higher intensity support for parents who do not achieve satisfactory results initially. En ligne : https://doi.org/10.1016/j.rasd.2024.102456 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

Toe walking in children and adolescents with Autism Spectrum Disorder: Relationship with sensory and motor functions,language, cognition, and autism severity / Roberto SACCO ; Maria BONCODDO ; Fabiana BELLOMO ; Francesca CUCINOTTA ; Arianna RICCIARDELLO ; Laura TURRIZIANI ; Pasquale TOMAIUOLO ; Riccardo Cuoghi COSTANTINI ; Roberto D'AMICO ; Antonio M. PERSICO in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102457 Titre : Toe walking in children and adolescents with Autism Spectrum Disorder: Relationship with sensory and motor functions,language, cognition, and autism severity Type de document : Texte imprimé et/ou numérique Auteurs : Roberto SACCO, Auteur ; Maria BONCODDO, Auteur ; Fabiana BELLOMO, Auteur ; Francesca CUCINOTTA, Auteur ; Arianna RICCIARDELLO, Auteur ; Laura TURRIZIANI, Auteur ; Pasquale TOMAIUOLO, Auteur ; Riccardo Cuoghi COSTANTINI, Auteur ; Roberto D'AMICO, Auteur ; Antonio M. PERSICO, Auteur Article en page(s) : p.102457 Langues : Anglais (eng) Mots-clés : Autism  Autism Spectrum Disorder  Intellectual Disability  Primitive reflex  Sensory profile  Toe walking Index. décimale : PER Périodiques Résumé : Background Children and adolescents with Autism Spectrum Disorder (ASD) often present motor signs and symptoms, including toe walking (TW). The pathophysiology of TW in ASD is not fully understood. In particular, it is debated whether it may represent a persistent primitive walking pattern or the result of abnormal processing of sensory input from the lower limbs and feet. The present study is aimed at assessing the association between TW and cognitive, sensory, motor and language functions, as well as autism severity. Method We enrolled 112 children and adolescents with ASD, 61 with TW and 51 without TW. A complete psychodiagnostic assessment was performed, including ADOS-2, ADI-R, PEP-3, IQ testing or Griffiths Mental Developmental Scales, and Short Sensory Profile. Results Children and adolescents with TW have significantly lower cognitive level, greater language and motor impairment, as well as greater autism severity. Instead, no difference in severity of sensory abnormalities or in sensory profile emerges between cases with and without TW. Conclusions the present data are most compatible with a model interpreting TW as a behavioral pattern resulting from the persistence of a primitive walking pattern (i.e. lack of heel strike, prior to the acquisition of plantar walking) or possibly of archaic tonic reflexes, rather than as a consequence primarily of abnormal sensory processing. Health practitioners should monitor the gait of autistic children and plan appropriate interventions, aimed at promoting the adoption of more mature plantar walking patterns. En ligne : https://doi.org/10.1016/j.rasd.2024.102457 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] Toe walking in children and adolescents with Autism Spectrum Disorder: Relationship with sensory and motor functions,language, cognition, and autism severity [Texte imprimé et/ou numérique] / Roberto SACCO, Auteur ; Maria BONCODDO, Auteur ; Fabiana BELLOMO, Auteur ; Francesca CUCINOTTA, Auteur ; Arianna RICCIARDELLO, Auteur ; Laura TURRIZIANI, Auteur ; Pasquale TOMAIUOLO, Auteur ; Riccardo Cuoghi COSTANTINI, Auteur ; Roberto D'AMICO, Auteur ; Antonio M. PERSICO, Auteur . - p.102457. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102457 Mots-clés : Autism  Autism Spectrum Disorder  Intellectual Disability  Primitive reflex  Sensory profile  Toe walking Index. décimale : PER Périodiques Résumé : Background Children and adolescents with Autism Spectrum Disorder (ASD) often present motor signs and symptoms, including toe walking (TW). The pathophysiology of TW in ASD is not fully understood. In particular, it is debated whether it may represent a persistent primitive walking pattern or the result of abnormal processing of sensory input from the lower limbs and feet. The present study is aimed at assessing the association between TW and cognitive, sensory, motor and language functions, as well as autism severity. Method We enrolled 112 children and adolescents with ASD, 61 with TW and 51 without TW. A complete psychodiagnostic assessment was performed, including ADOS-2, ADI-R, PEP-3, IQ testing or Griffiths Mental Developmental Scales, and Short Sensory Profile. Results Children and adolescents with TW have significantly lower cognitive level, greater language and motor impairment, as well as greater autism severity. Instead, no difference in severity of sensory abnormalities or in sensory profile emerges between cases with and without TW. Conclusions the present data are most compatible with a model interpreting TW as a behavioral pattern resulting from the persistence of a primitive walking pattern (i.e. lack of heel strike, prior to the acquisition of plantar walking) or possibly of archaic tonic reflexes, rather than as a consequence primarily of abnormal sensory processing. Health practitioners should monitor the gait of autistic children and plan appropriate interventions, aimed at promoting the adoption of more mature plantar walking patterns. En ligne : https://doi.org/10.1016/j.rasd.2024.102457 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

Identifying the functions of restricted and repetitive behaviours and interests in Autism: A scoping review / Ève PICARD ; Isabelle SOULIERES ; Armando BERTONE in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102458 Titre : Identifying the functions of restricted and repetitive behaviours and interests in Autism: A scoping review Type de document : Texte imprimé et/ou numérique Auteurs : Ève PICARD, Auteur ; Isabelle SOULIERES, Auteur ; Armando BERTONE, Auteur Article en page(s) : p.102458 Langues : Anglais (eng) Mots-clés : Restricted and repetitive behaviours and interests  RRBIs  Autism  Functions Index. décimale : PER Périodiques Résumé : Restricted and repetitive behaviours and interests (RRBIs) are common and integral to the everyday living of autistic persons. While RRBIs are often seen as negative behaviours to be subdued, they may serve regulatory roles that are central to an autistic way of being. Moreover, RRBIs are often present in early childhood and are associated with developmental benefits. Therefore, the continued presence of RRBIs among autistic persons beyond early childhood suggests that RRBIs may serve adaptive functions. To inform and improve clinical decision-making and gain a deeper understanding of the adaptive roles of RRBIs, a scoping review methodology was used to identify the key functions of RRBIs in autism. Our results resulted in 21 studies from the PsycINFO and Medline databases among the 3162 studies on RRBIs published between 2010 and 2023 retrieved. Four themes of functions were identified and mapped onto the subdomains of RRBIs. Specifically, results indicated that RRBIs (i) help autistic persons regulate sensory experiences, (ii) cope with feelings of anxiety, (iii) introduce certainty to their environment, and (iv) make sense of their world. This paper highlights the constructive characteristics of RRBIs and presents an alternative perspective to understand them and help inform decisions about whether and how RRBIs should be managed. Future research should focus on gathering qualitative insights into RRBIs from the perspectives of autistic persons and developing nuanced approaches to managing RRBIs by considering their functions. En ligne : https://doi.org/10.1016/j.rasd.2024.102458 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] Identifying the functions of restricted and repetitive behaviours and interests in Autism: A scoping review [Texte imprimé et/ou numérique] / Ève PICARD, Auteur ; Isabelle SOULIERES, Auteur ; Armando BERTONE, Auteur . - p.102458. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102458 Mots-clés : Restricted and repetitive behaviours and interests  RRBIs  Autism  Functions Index. décimale : PER Périodiques Résumé : Restricted and repetitive behaviours and interests (RRBIs) are common and integral to the everyday living of autistic persons. While RRBIs are often seen as negative behaviours to be subdued, they may serve regulatory roles that are central to an autistic way of being. Moreover, RRBIs are often present in early childhood and are associated with developmental benefits. Therefore, the continued presence of RRBIs among autistic persons beyond early childhood suggests that RRBIs may serve adaptive functions. To inform and improve clinical decision-making and gain a deeper understanding of the adaptive roles of RRBIs, a scoping review methodology was used to identify the key functions of RRBIs in autism. Our results resulted in 21 studies from the PsycINFO and Medline databases among the 3162 studies on RRBIs published between 2010 and 2023 retrieved. Four themes of functions were identified and mapped onto the subdomains of RRBIs. Specifically, results indicated that RRBIs (i) help autistic persons regulate sensory experiences, (ii) cope with feelings of anxiety, (iii) introduce certainty to their environment, and (iv) make sense of their world. This paper highlights the constructive characteristics of RRBIs and presents an alternative perspective to understand them and help inform decisions about whether and how RRBIs should be managed. Future research should focus on gathering qualitative insights into RRBIs from the perspectives of autistic persons and developing nuanced approaches to managing RRBIs by considering their functions. En ligne : https://doi.org/10.1016/j.rasd.2024.102458 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

A systematic review of cardiac autonomic reactivity to face-to-face social stressor stimuli in children and adolescents with autism spectrum disorder / Samantha BURNS ; Selena CHEN ; Earl WOODRUFF in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102459 Titre : A systematic review of cardiac autonomic reactivity to face-to-face social stressor stimuli in children and adolescents with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Samantha BURNS, Auteur ; Selena CHEN, Auteur ; Earl WOODRUFF, Auteur Article en page(s) : p.102459 Langues : Anglais (eng) Mots-clés : Social stressor  Systematic review  Children  Adolescents  Autism spectrum disorder  Cardiac autonomic reactivity Index. décimale : PER Périodiques Résumé : Background Research suggests that individuals with autism spectrum disorder (ASD) exhibit heightened responses to social stressors, putting them at higher risk to psychopathology. However, the findings are inconsistent. Considering the unavoidable social interactions in daily life, synthesizing the literature on physiological reactivity to social stressor stimuli in individuals with ASD is crucial. Aims To investigate the cardiac autonomic reactivity to face-to-face social stressor stimuli in children and adolescents with ASD. Methods Literature was identified from four databases and grey literature. The inclusion criteria were children and youth with ASD aged 18 or below, social stimuli that occurred face-to-face, and physiological measures of cardiac autonomic reactivity. Results Twenty studies were included, with a sample size of 1064 (548 ASD samples). Five unique measures were reported. A preliminary pattern of blunted respiratory sinus arrhythmia (RSA) reactivity was found in ASD compared to the typically developing (TD) individuals. Interestingly, a pattern of higher or no significant differences in heart rate (HR) responses in ASD compared to TD was noted when a familiar person was used, but blunted when a novel person was used. Conclusions Atypical cardiac autonomic reactivity in ASD was demonstrated with contrasting responses depending on familiarity. Implications for interventions are discussed. En ligne : https://doi.org/10.1016/j.rasd.2024.102459 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] A systematic review of cardiac autonomic reactivity to face-to-face social stressor stimuli in children and adolescents with autism spectrum disorder [Texte imprimé et/ou numérique] / Samantha BURNS, Auteur ; Selena CHEN, Auteur ; Earl WOODRUFF, Auteur . - p.102459. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102459 Mots-clés : Social stressor  Systematic review  Children  Adolescents  Autism spectrum disorder  Cardiac autonomic reactivity Index. décimale : PER Périodiques Résumé : Background Research suggests that individuals with autism spectrum disorder (ASD) exhibit heightened responses to social stressors, putting them at higher risk to psychopathology. However, the findings are inconsistent. Considering the unavoidable social interactions in daily life, synthesizing the literature on physiological reactivity to social stressor stimuli in individuals with ASD is crucial. Aims To investigate the cardiac autonomic reactivity to face-to-face social stressor stimuli in children and adolescents with ASD. Methods Literature was identified from four databases and grey literature. The inclusion criteria were children and youth with ASD aged 18 or below, social stimuli that occurred face-to-face, and physiological measures of cardiac autonomic reactivity. Results Twenty studies were included, with a sample size of 1064 (548 ASD samples). Five unique measures were reported. A preliminary pattern of blunted respiratory sinus arrhythmia (RSA) reactivity was found in ASD compared to the typically developing (TD) individuals. Interestingly, a pattern of higher or no significant differences in heart rate (HR) responses in ASD compared to TD was noted when a familiar person was used, but blunted when a novel person was used. Conclusions Atypical cardiac autonomic reactivity in ASD was demonstrated with contrasting responses depending on familiarity. Implications for interventions are discussed. En ligne : https://doi.org/10.1016/j.rasd.2024.102459 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

Exploring the effects of age and sex on sensory sensitivities in middle and older aged autistic adults / Goldie A. MCQUAID ; Gregory L. WALLACE in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102460 Titre : Exploring the effects of age and sex on sensory sensitivities in middle and older aged autistic adults Type de document : Texte imprimé et/ou numérique Auteurs : Goldie A. MCQUAID, Auteur ; Gregory L. WALLACE, Auteur Article en page(s) : p.102460 Langues : Anglais (eng) Mots-clés : Adulthood  Ageing  Autism  Sensory acuity  Sensory sensitivities  Sex differences Index. décimale : PER Périodiques Résumé : Purpose Although sensory sensitivities are common among autistic people, few studies have explored how they may be impacted by ageing. Little is known about the experiences of autistic people across adulthood or about the experiences of people assigned female-at-birth. Some results suggest that autistic people assigned female-at-birth report more sensory sensitivities, but little is known about experiences in middle-aged and older autistic people assigned female-at-birth. Methods This study explored self-reported sensory sensitivities and sensory acuity in 210 autistic people aged 42-80 years old. Associations between age and sensory sensitivities were examined using correlational and regression analyses, and t-tests explored differences based on sex-assigned-at-birth. Results No significant correlation was observed between age and sensory sensitivities, although older age was associated with poorer sensory acuity. Poorer acuity in vision and hearing was associated with more sensory sensitivities. People assigned female-at-birth reported higher scores for overall sensory sensitivities and low temperature/pain tolerance. Sex-assigned-at-birth, sensory acuity and an age-x-sensory acuity interaction term contributed significantly to a regression model explaining overall sensory sensitivity, but age did not contribute significantly. Conclusion This cross-sectional study suggests that sensory sensitivities are stable across middle-age and older adulthood. Results contrast with previous studies in young adults which have suggested reduction in sensory sensitivities with age. In keeping with studies of younger people, middle-age and older autistic adults assigned female-at-birth report higher rates of sensory sensitivities than comparably aged autistic adults assigned male-at-birth. If further studies examining individual change in sensory sensitives replicate these results, then they may contribute to understanding care needs of autistic older people. En ligne : https://doi.org/10.1016/j.rasd.2024.102460 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] Exploring the effects of age and sex on sensory sensitivities in middle and older aged autistic adults [Texte imprimé et/ou numérique] / Goldie A. MCQUAID, Auteur ; Gregory L. WALLACE, Auteur . - p.102460. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102460 Mots-clés : Adulthood  Ageing  Autism  Sensory acuity  Sensory sensitivities  Sex differences Index. décimale : PER Périodiques Résumé : Purpose Although sensory sensitivities are common among autistic people, few studies have explored how they may be impacted by ageing. Little is known about the experiences of autistic people across adulthood or about the experiences of people assigned female-at-birth. Some results suggest that autistic people assigned female-at-birth report more sensory sensitivities, but little is known about experiences in middle-aged and older autistic people assigned female-at-birth. Methods This study explored self-reported sensory sensitivities and sensory acuity in 210 autistic people aged 42-80 years old. Associations between age and sensory sensitivities were examined using correlational and regression analyses, and t-tests explored differences based on sex-assigned-at-birth. Results No significant correlation was observed between age and sensory sensitivities, although older age was associated with poorer sensory acuity. Poorer acuity in vision and hearing was associated with more sensory sensitivities. People assigned female-at-birth reported higher scores for overall sensory sensitivities and low temperature/pain tolerance. Sex-assigned-at-birth, sensory acuity and an age-x-sensory acuity interaction term contributed significantly to a regression model explaining overall sensory sensitivity, but age did not contribute significantly. Conclusion This cross-sectional study suggests that sensory sensitivities are stable across middle-age and older adulthood. Results contrast with previous studies in young adults which have suggested reduction in sensory sensitivities with age. In keeping with studies of younger people, middle-age and older autistic adults assigned female-at-birth report higher rates of sensory sensitivities than comparably aged autistic adults assigned male-at-birth. If further studies examining individual change in sensory sensitives replicate these results, then they may contribute to understanding care needs of autistic older people. En ligne : https://doi.org/10.1016/j.rasd.2024.102460 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

A cross-linguistic examination of language measures in autism: A comparison between Dutch and English / Yanru CHEN ; Ellen DEMURIE ; Maide ERDOGAN ; Sarah SCHAUBROECK ; Helen TAGER-FLUSBERG ; Herbert ROEYERS in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102461 Titre : A cross-linguistic examination of language measures in autism: A comparison between Dutch and English Type de document : Texte imprimé et/ou numérique Auteurs : Yanru CHEN, Auteur ; Ellen DEMURIE, Auteur ; Maide ERDOGAN, Auteur ; Sarah SCHAUBROECK, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Herbert ROEYERS, Auteur Article en page(s) : p.102461 Langues : Anglais (eng) Mots-clés : Autism  Language  Development  Assessment modality  Cross-linguistic Index. décimale : PER Périodiques Résumé : Background Language abilities are highly heterogeneous in autism. While a multimodal assessment approach is recommended to capture the language variability, this is not always possible. Therefore, it is important to gain contextual information about different language assessments to determine which assessment is most appropriate for different research questions. As most current work is based on English-speaking populations, this paper compares three language assessment modalities (standardized assessment, parent survey, and a natural language sample) between English-speaking and Dutch-speaking autistic and neurotypical children. Method The Mullen Scales of Early Learning, the Vineland Adaptive Behavior Scales and a naturalistic language sample were employed to measure language in 100 preschool-aged participants. Correlation analyses and mixed-effect regressions were conducted, and Bland-Altman plots were created to examine the similarity between measures. Results English-speaking and Dutch-speaking parents rated their children?s expressive language higher than their receptive language. The best agreement between measures was for standardized language and parent report. Agreement was higher for children with low language scores. Primary language (English vs. Dutch) did not significantly affect the results, but age, nonverbal cognitive abilities and biological sex were shown to predict expressive and receptive language outcome. Conclusions For autistic children with low language levels, parent-reported and standardized language measures provide researchers with similar information. Depending on the available time and resources, researchers may choose to use one of these methods. However, for autistic children with (above) average language abilities, multiple modalities should be considered to gain a comprehensive understanding of their language abilities across different settings. A natural language sample is of most added value next to a standardized assessment or parent report. En ligne : https://doi.org/10.1016/j.rasd.2024.102461 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] A cross-linguistic examination of language measures in autism: A comparison between Dutch and English [Texte imprimé et/ou numérique] / Yanru CHEN, Auteur ; Ellen DEMURIE, Auteur ; Maide ERDOGAN, Auteur ; Sarah SCHAUBROECK, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Herbert ROEYERS, Auteur . - p.102461. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102461 Mots-clés : Autism  Language  Development  Assessment modality  Cross-linguistic Index. décimale : PER Périodiques Résumé : Background Language abilities are highly heterogeneous in autism. While a multimodal assessment approach is recommended to capture the language variability, this is not always possible. Therefore, it is important to gain contextual information about different language assessments to determine which assessment is most appropriate for different research questions. As most current work is based on English-speaking populations, this paper compares three language assessment modalities (standardized assessment, parent survey, and a natural language sample) between English-speaking and Dutch-speaking autistic and neurotypical children. Method The Mullen Scales of Early Learning, the Vineland Adaptive Behavior Scales and a naturalistic language sample were employed to measure language in 100 preschool-aged participants. Correlation analyses and mixed-effect regressions were conducted, and Bland-Altman plots were created to examine the similarity between measures. Results English-speaking and Dutch-speaking parents rated their children?s expressive language higher than their receptive language. The best agreement between measures was for standardized language and parent report. Agreement was higher for children with low language scores. Primary language (English vs. Dutch) did not significantly affect the results, but age, nonverbal cognitive abilities and biological sex were shown to predict expressive and receptive language outcome. Conclusions For autistic children with low language levels, parent-reported and standardized language measures provide researchers with similar information. Depending on the available time and resources, researchers may choose to use one of these methods. However, for autistic children with (above) average language abilities, multiple modalities should be considered to gain a comprehensive understanding of their language abilities across different settings. A natural language sample is of most added value next to a standardized assessment or parent report. En ligne : https://doi.org/10.1016/j.rasd.2024.102461 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

An examination of sleep problems and parental well-being, comparing families with and without autistic children / Sally WHELAN ; Geraldine LEADER in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102462 Titre : An examination of sleep problems and parental well-being, comparing families with and without autistic children Type de document : Texte imprimé et/ou numérique Auteurs : Sally WHELAN, Auteur ; Geraldine LEADER, Auteur Article en page(s) : p.102462 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Sleep quality  Parental stress  Actigraphy  Maternal well-being  Maternal quality of life  Family medical history  Autoimmune disease Index. décimale : PER Périodiques Résumé : Background Sleep problems are a common comorbidity in autistic children and adolescents. Little is known about the role of sleep problems in parental well-being in the context of autism. Method The current study utilised actigraphy and questionnaire-based measures in mothers of autistic children and adolescents (n = 11), and mothers of typically developing (TD) children and adolescents (n = 11). Actigraphy is an objective, non-intrusive method for examining sleep. It involves wearing a wristwatch-like microcomputer that records motion. Measures included the Pittsburgh Sleep Quality Index, Autoimmune Disease in Family Members Questionnaire, Parenting Stress Index-Short Form, World Health Organization Quality of Life Abbreviated Version (WHOQOL-BREF), Hospital Anxiety and Depression Scale, and the Multidimensional Scale of Perceived Social Support. Results Mothers of autistic children had significantly greater difficulties with subjective sleep quality, sleep duration, sleep efficiency, and daytime dysfunction, than mothers of TD children. In mothers of autistic children, parental use of sleep medication on the PSQI was positively associated with objective sleep onset latency using actigraphy, with a large effect size. Families with an autistic child had significantly more family members with osteoarthritis and rheumatoid arthritis than did families of TD children. Families of autistic children had significantly more autistic family members than did families of TD children. Conclusions Mothers of autistic children had significantly higher levels of stress, anxiety, depression, and lower levels of quality of life and perceived social support, than parents of TD children. Sleep problems identified via actigraphy were associated with parental stress, anxiety and depression, and quality of life. En ligne : https://doi.org/10.1016/j.rasd.2024.102462 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] An examination of sleep problems and parental well-being, comparing families with and without autistic children [Texte imprimé et/ou numérique] / Sally WHELAN, Auteur ; Geraldine LEADER, Auteur . - p.102462. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102462 Mots-clés : Autism spectrum disorder  Sleep quality  Parental stress  Actigraphy  Maternal well-being  Maternal quality of life  Family medical history  Autoimmune disease Index. décimale : PER Périodiques Résumé : Background Sleep problems are a common comorbidity in autistic children and adolescents. Little is known about the role of sleep problems in parental well-being in the context of autism. Method The current study utilised actigraphy and questionnaire-based measures in mothers of autistic children and adolescents (n = 11), and mothers of typically developing (TD) children and adolescents (n = 11). Actigraphy is an objective, non-intrusive method for examining sleep. It involves wearing a wristwatch-like microcomputer that records motion. Measures included the Pittsburgh Sleep Quality Index, Autoimmune Disease in Family Members Questionnaire, Parenting Stress Index-Short Form, World Health Organization Quality of Life Abbreviated Version (WHOQOL-BREF), Hospital Anxiety and Depression Scale, and the Multidimensional Scale of Perceived Social Support. Results Mothers of autistic children had significantly greater difficulties with subjective sleep quality, sleep duration, sleep efficiency, and daytime dysfunction, than mothers of TD children. In mothers of autistic children, parental use of sleep medication on the PSQI was positively associated with objective sleep onset latency using actigraphy, with a large effect size. Families with an autistic child had significantly more family members with osteoarthritis and rheumatoid arthritis than did families of TD children. Families of autistic children had significantly more autistic family members than did families of TD children. Conclusions Mothers of autistic children had significantly higher levels of stress, anxiety, depression, and lower levels of quality of life and perceived social support, than parents of TD children. Sleep problems identified via actigraphy were associated with parental stress, anxiety and depression, and quality of life. En ligne : https://doi.org/10.1016/j.rasd.2024.102462 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

Facing Your Fears in autistic youth with co-occurring psychiatric conditions: Reductions in symptoms of anxiety and depression / K. TURNER ; K. JOHNSTON ; C. A. CLARK ; S. J. HOWE ; M. MCCONNELL ; K. MCFEE in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102463 Titre : Facing Your Fears in autistic youth with co-occurring psychiatric conditions: Reductions in symptoms of anxiety and depression Type de document : Texte imprimé et/ou numérique Auteurs : K. TURNER, Auteur ; K. JOHNSTON, Auteur ; C. A. CLARK, Auteur ; S. J. HOWE, Auteur ; M. MCCONNELL, Auteur ; K. MCFEE, Auteur Article en page(s) : p.102463 Langues : Anglais (eng) Mots-clés : Autism  Anxiety  Depression  Cognitive behaviour therapy  Psychiatric complexity Index. décimale : PER Périodiques Résumé : Autistic youth often experience psychiatric complexity, with up to 70 % of youth experiencing at least one mental health issue, and as many as 41 % experiencing two or more issues simultaneously, or complex psychiatric comorbidity. Adapted cognitive behaviour therapy (CBT) for anxiety is effective in reducing anxiety symptoms in autistic youth who have multiple anxiety conditions, as well as other psychiatric conditions (e.g., attention deficit hyperactivity disorder; ADHD). However, few studies have examined the secondary impact of CBT for anxiety on depressive symptoms, despite the high prevalence of depression in autistic youth. Additionally, it is unknown how psychiatric complexity may impact, or moderate, autistic youth?s response to treatment. Fifty-one autistic youth (8-13 years old) participated in an adapted CBT intervention for anxiety (Facing Your Fears). Participants were categorized into one of three groups of increasing psychiatric complexity (Anxiety only; Anxiety + ADHD; and Anxiety + other mental health conditions). Paired sample t-tests and linear mixed models highlighted that autistic youth generally benefitted from CBT for anxiety, as seen in reductions of anxiety and depressive symptoms. Caregivers of youth in all diagnostic groups reported a significant reduction in anxiety symptoms and depression at post-treatment; however, only youth in the Anxiety only group, or those with less psychiatric complexity, reported a reduction in anxiety. Autistic youth did not report any changes in depressive symptoms, regardless of psychiatric complexity. Further study is needed to determine if symptom reductions continue overtime, and whether participating in adapted CBT for anxiety is associated with reductions in other mental health symptoms. En ligne : https://doi.org/10.1016/j.rasd.2024.102463 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] Facing Your Fears in autistic youth with co-occurring psychiatric conditions: Reductions in symptoms of anxiety and depression [Texte imprimé et/ou numérique] / K. TURNER, Auteur ; K. JOHNSTON, Auteur ; C. A. CLARK, Auteur ; S. J. HOWE, Auteur ; M. MCCONNELL, Auteur ; K. MCFEE, Auteur . - p.102463. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102463 Mots-clés : Autism  Anxiety  Depression  Cognitive behaviour therapy  Psychiatric complexity Index. décimale : PER Périodiques Résumé : Autistic youth often experience psychiatric complexity, with up to 70 % of youth experiencing at least one mental health issue, and as many as 41 % experiencing two or more issues simultaneously, or complex psychiatric comorbidity. Adapted cognitive behaviour therapy (CBT) for anxiety is effective in reducing anxiety symptoms in autistic youth who have multiple anxiety conditions, as well as other psychiatric conditions (e.g., attention deficit hyperactivity disorder; ADHD). However, few studies have examined the secondary impact of CBT for anxiety on depressive symptoms, despite the high prevalence of depression in autistic youth. Additionally, it is unknown how psychiatric complexity may impact, or moderate, autistic youth?s response to treatment. Fifty-one autistic youth (8-13 years old) participated in an adapted CBT intervention for anxiety (Facing Your Fears). Participants were categorized into one of three groups of increasing psychiatric complexity (Anxiety only; Anxiety + ADHD; and Anxiety + other mental health conditions). Paired sample t-tests and linear mixed models highlighted that autistic youth generally benefitted from CBT for anxiety, as seen in reductions of anxiety and depressive symptoms. Caregivers of youth in all diagnostic groups reported a significant reduction in anxiety symptoms and depression at post-treatment; however, only youth in the Anxiety only group, or those with less psychiatric complexity, reported a reduction in anxiety. Autistic youth did not report any changes in depressive symptoms, regardless of psychiatric complexity. Further study is needed to determine if symptom reductions continue overtime, and whether participating in adapted CBT for anxiety is associated with reductions in other mental health symptoms. En ligne : https://doi.org/10.1016/j.rasd.2024.102463 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

Autism spectrum disorder (ASD) diagnosis: A biochemical investigation into the diagnostic utility of S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH) levels and the SAM/SAH ratio / Zafer YÖNDEN ; Amin DAEMI ; Yusuf DÖ?Ü? ; Hülya BINOKAY ; Perihan Çam RAY ; Ça?lar Charles Daniel JAICKS in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102464 Titre : Autism spectrum disorder (ASD) diagnosis: A biochemical investigation into the diagnostic utility of S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH) levels and the SAM/SAH ratio Type de document : Texte imprimé et/ou numérique Auteurs : Zafer YÖNDEN, Auteur ; Amin DAEMI, Auteur ; Yusuf DÖ?Ü?, Auteur ; Hülya BINOKAY, Auteur ; Perihan Çam RAY, Auteur ; Ça?lar Charles Daniel JAICKS, Auteur Article en page(s) : p.102464 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder (ASD)  S-Adenosyl Methionine (SAM)  S-adenosyl homocysteine (SAH)  SAM/SAH Ratio  Glycine N-methyltransferase (GNMT)  Methylation Cycle Index. décimale : PER Périodiques Résumé : Background The balance between SAM and SAH ratios is critical for cellular methylation capacity such that a decrease in this ratio signals decrease the methylation potential, impacting cellular functions. In Autism Spectrum Disorder (ASD), impaired methylation processes are prominent, disrupting essential methyl group transfers crucial for DNA methylation, neurotransmitter synthesis, and detoxification. This disturbance affects gene expression and neural function, contributing to ASD development. This paper aims to explore ASD's pathogenesis by investigating biochemical parameters linked to the methylation cycle. For this purpose, some laboratory parameters are employed to aid in the understanding of potential laboratory abnormalities in ASD in children aged 2 to 8 years. Materials and Methods This study included a cohort of 43 children aged 2 to 8 years diagnosed ASD, alongside a control group of 43 age-and gender-matched healthy subjects. The serum of blood samples taken was used to measure biochemical factors. Specimens were processed using ELISA instrumentation and hemogram auto analyzers. The study conducted a statistical comparison between the ASD-diagnosed subjects and healthy controls, focusing on levels of S-adenosyl methionine (SAM), S-adenosyl homocysteine (SAH), Glycine N-methyltransferase (GNMT), and platelet counts. RESULTS The levels of SAH and platelets were significantly higher in the case group compared to the control group. Conversely, levels of SAM, as well as the SAM/SAH ratio, were found to be significantly lower in the case group than in the control group (p < 0.05). No statistically significant difference was observed in the levels of GNMT when compared (p > 0.05). Receiver Operating Characteristic (ROC) analysis revealed that the diagnostic performance for SAM had an area under the curve (AUC) of 0.876, with a cut-off point determined at 286.9 ng/mL, yielding a sensitivity of 85 % and a specificity of 75 %. For SAH, the AUC was calculated to be 0.671, with a cut-off point set at 0.49 ng/mL, resulting in a sensitivity and specificity of 64 %. The SAM/SAH ratio demonstrated an AUC of 0.806, with the cut-off point established at 576.3, leading to a sensitivity and specificity of 72 %. A significant negative correlation was detected between the scores of the Modified Checklist for Autism in Toddlers (M-CHAT) and both SAM levels and the SAM/SAH ratio. The analysis indicated that an increase of one unit (1 ng/mL) in SAM levels is associated with a decreased autism risk by a factor of 1/0.914 = 1.1 %, whereas an increase of one unit (1 * 103/uL) in platelet count is associated with an increased autism risk by a factor of 1.019 %. Regarding glycine N-methyltransferase, no significant difference was observed between the two groups. Conclusion Follow-up studies with larger samples will be needed to better understand the potential for SAM, SAH, and SAM/SAH as a potential biomarker, at least for a subset of those with ASD. The correlation between these markers and the total score on the M-Chat raises further interest in this possibility. The correlation between these markers and the total score on the M-Chat further supports their utility as clinical biochemical laboratory parameters that could aid in the diagnosis of ASD. En ligne : https://doi.org/10.1016/j.rasd.2024.102464 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] Autism spectrum disorder (ASD) diagnosis: A biochemical investigation into the diagnostic utility of S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH) levels and the SAM/SAH ratio [Texte imprimé et/ou numérique] / Zafer YÖNDEN, Auteur ; Amin DAEMI, Auteur ; Yusuf DÖ?Ü?, Auteur ; Hülya BINOKAY, Auteur ; Perihan Çam RAY, Auteur ; Ça?lar Charles Daniel JAICKS, Auteur . - p.102464. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102464 Mots-clés : Autism spectrum disorder (ASD)  S-Adenosyl Methionine (SAM)  S-adenosyl homocysteine (SAH)  SAM/SAH Ratio  Glycine N-methyltransferase (GNMT)  Methylation Cycle Index. décimale : PER Périodiques Résumé : Background The balance between SAM and SAH ratios is critical for cellular methylation capacity such that a decrease in this ratio signals decrease the methylation potential, impacting cellular functions. In Autism Spectrum Disorder (ASD), impaired methylation processes are prominent, disrupting essential methyl group transfers crucial for DNA methylation, neurotransmitter synthesis, and detoxification. This disturbance affects gene expression and neural function, contributing to ASD development. This paper aims to explore ASD's pathogenesis by investigating biochemical parameters linked to the methylation cycle. For this purpose, some laboratory parameters are employed to aid in the understanding of potential laboratory abnormalities in ASD in children aged 2 to 8 years. Materials and Methods This study included a cohort of 43 children aged 2 to 8 years diagnosed ASD, alongside a control group of 43 age-and gender-matched healthy subjects. The serum of blood samples taken was used to measure biochemical factors. Specimens were processed using ELISA instrumentation and hemogram auto analyzers. The study conducted a statistical comparison between the ASD-diagnosed subjects and healthy controls, focusing on levels of S-adenosyl methionine (SAM), S-adenosyl homocysteine (SAH), Glycine N-methyltransferase (GNMT), and platelet counts. RESULTS The levels of SAH and platelets were significantly higher in the case group compared to the control group. Conversely, levels of SAM, as well as the SAM/SAH ratio, were found to be significantly lower in the case group than in the control group (p < 0.05). No statistically significant difference was observed in the levels of GNMT when compared (p > 0.05). Receiver Operating Characteristic (ROC) analysis revealed that the diagnostic performance for SAM had an area under the curve (AUC) of 0.876, with a cut-off point determined at 286.9 ng/mL, yielding a sensitivity of 85 % and a specificity of 75 %. For SAH, the AUC was calculated to be 0.671, with a cut-off point set at 0.49 ng/mL, resulting in a sensitivity and specificity of 64 %. The SAM/SAH ratio demonstrated an AUC of 0.806, with the cut-off point established at 576.3, leading to a sensitivity and specificity of 72 %. A significant negative correlation was detected between the scores of the Modified Checklist for Autism in Toddlers (M-CHAT) and both SAM levels and the SAM/SAH ratio. The analysis indicated that an increase of one unit (1 ng/mL) in SAM levels is associated with a decreased autism risk by a factor of 1/0.914 = 1.1 %, whereas an increase of one unit (1 * 103/uL) in platelet count is associated with an increased autism risk by a factor of 1.019 %. Regarding glycine N-methyltransferase, no significant difference was observed between the two groups. Conclusion Follow-up studies with larger samples will be needed to better understand the potential for SAM, SAH, and SAM/SAH as a potential biomarker, at least for a subset of those with ASD. The correlation between these markers and the total score on the M-Chat raises further interest in this possibility. The correlation between these markers and the total score on the M-Chat further supports their utility as clinical biochemical laboratory parameters that could aid in the diagnosis of ASD. En ligne : https://doi.org/10.1016/j.rasd.2024.102464 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

The effects of the COVID-19 pandemic on mental health in mothers of autistic children and mothers of children with fragile X syndrome / Laura FRIEDMAN ; Katherine BANGERT ; Alexandra HICKEY ; Jennifer SUN ; Jessica KLUSEK in Research in Autism Spectrum Disorders, 117 (September 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 117 (September 2024) . - p.102465 Titre : The effects of the COVID-19 pandemic on mental health in mothers of autistic children and mothers of children with fragile X syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Laura FRIEDMAN, Auteur ; Katherine BANGERT, Auteur ; Alexandra HICKEY, Auteur ; Jennifer SUN, Auteur ; Jessica KLUSEK, Auteur Article en page(s) : p.102465 Langues : Anglais (eng) Mots-clés : Psychological well-being  Anxiety  Depression  Caregiver burden  Social support Index. décimale : PER Périodiques Résumé : Background The COVID-19 pandemic adversely affected the mental health of American mothers and mothers of children with disabilities may have been disproportionately impacted. The present study characterized psychological well-being, social support, and caregiving responsibilities during the pandemic across mothers of children with autism, fragile X syndrome (FXS), and neurotypical children. Methods Participants were 54 mothers of children with FXS, 46 mothers of autistic children, and a control group of 80 mothers of neurotypical children. Mothers completed questionnaires on depressive and anxiety symptoms, perceived decline in psychological well-being due to the pandemic, pandemic-related changes in caregiving responsibilities, and levels of social support. Results Over half of the mothers of children with autism and over one-third of the mothers of children with FXS reported clinically significant symptoms of depression and anxiety, with rates significantly higher than the control mothers. Though all mothers reported a surge in caregiving responsibilities, mothers of children with FXS experienced greater increases in caregiving responsibilities and social support was lower in both disability groups. Caregiving responsibilities and social support were associated with psychological well-being due to the pandemic across all groups. Conclusions Findings highlight the harsh impact of the pandemic on the mental health of mothers of children with FXS and autism. The staggering rate of clinical depressive and anxiety symptoms reported by these groups underscores the urgent need for improved access to psychological services and family-centered supports, with increased caregiving responsibilities and inadequate social support representing important risk factors for mental health problems. En ligne : https://doi.org/10.1016/j.rasd.2024.102465 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] The effects of the COVID-19 pandemic on mental health in mothers of autistic children and mothers of children with fragile X syndrome [Texte imprimé et/ou numérique] / Laura FRIEDMAN, Auteur ; Katherine BANGERT, Auteur ; Alexandra HICKEY, Auteur ; Jennifer SUN, Auteur ; Jessica KLUSEK, Auteur . - p.102465. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 117 (September 2024) . - p.102465 Mots-clés : Psychological well-being  Anxiety  Depression  Caregiver burden  Social support Index. décimale : PER Périodiques Résumé : Background The COVID-19 pandemic adversely affected the mental health of American mothers and mothers of children with disabilities may have been disproportionately impacted. The present study characterized psychological well-being, social support, and caregiving responsibilities during the pandemic across mothers of children with autism, fragile X syndrome (FXS), and neurotypical children. Methods Participants were 54 mothers of children with FXS, 46 mothers of autistic children, and a control group of 80 mothers of neurotypical children. Mothers completed questionnaires on depressive and anxiety symptoms, perceived decline in psychological well-being due to the pandemic, pandemic-related changes in caregiving responsibilities, and levels of social support. Results Over half of the mothers of children with autism and over one-third of the mothers of children with FXS reported clinically significant symptoms of depression and anxiety, with rates significantly higher than the control mothers. Though all mothers reported a surge in caregiving responsibilities, mothers of children with FXS experienced greater increases in caregiving responsibilities and social support was lower in both disability groups. Caregiving responsibilities and social support were associated with psychological well-being due to the pandemic across all groups. Conclusions Findings highlight the harsh impact of the pandemic on the mental health of mothers of children with FXS and autism. The staggering rate of clinical depressive and anxiety symptoms reported by these groups underscores the urgent need for improved access to psychological services and family-centered supports, with increased caregiving responsibilities and inadequate social support representing important risk factors for mental health problems. En ligne : https://doi.org/10.1016/j.rasd.2024.102465 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534