Dépouillements

Editorial: Supporting families in the first 1,000 days of life – a balancing act / Maartje P. C. M. LUIJK in Journal of Child Psychology and Psychiatry, 66-10 (October 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1445-1448 Titre : Editorial: Supporting families in the first 1,000 days of life – a balancing act Type de document : texte imprimé Auteurs : Maartje P. C. M. LUIJK, Auteur ; Tessa J. ROSEBOOM, Auteur Article en page(s) : p.1445-1448 Langues : Anglais (eng) Mots-clés : Early-life experiences  parenting  infancy  social policy  child development Index. décimale : PER Périodiques Résumé : From the moment of fertilization, human development takes a phenomenal pace. In no other period of life are more biological and developmental milestones met than in the first 1,000 days after conception. All organs and systems are formed, and children start to discover the world, learn whom to trust and where to find comfort in times of distress. Evidence from biological, psychological, social and economic research shows that the environment in the first 1,000 days significantly impacts a person's ability to reach their full potential. Children who grow up in unpredictable and unsafe environments often struggle with the consequences for the rest of their lives. Investments in this critical period of human development have proven to be the most cost-effective way to improve lifelong health and well-being. Therefore, this period has gained interest both in political debate and society at large. In this contribution, we demonstrate that while the focus on the first 1,000 days is scientifically sound and historically grounded, it is time to reflect on its societal impact. We focus on its unintended negative consequences for parental well-being. Evidence for the importance of the first 1,000 days should drive collective action rather than reinforce individual blame. Parenting is not just a private matter; governments have a duty to provide parents with the resources to give their children the best start in life. En ligne : https://doi.org/10.1111/jcpp.70041 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] Editorial: Supporting families in the first 1,000 days of life – a balancing act [texte imprimé] / Maartje P. C. M. LUIJK, Auteur ; Tessa J. ROSEBOOM, Auteur . - p.1445-1448. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1445-1448 Mots-clés : Early-life experiences  parenting  infancy  social policy  child development Index. décimale : PER Périodiques Résumé : From the moment of fertilization, human development takes a phenomenal pace. In no other period of life are more biological and developmental milestones met than in the first 1,000 days after conception. All organs and systems are formed, and children start to discover the world, learn whom to trust and where to find comfort in times of distress. Evidence from biological, psychological, social and economic research shows that the environment in the first 1,000 days significantly impacts a person's ability to reach their full potential. Children who grow up in unpredictable and unsafe environments often struggle with the consequences for the rest of their lives. Investments in this critical period of human development have proven to be the most cost-effective way to improve lifelong health and well-being. Therefore, this period has gained interest both in political debate and society at large. In this contribution, we demonstrate that while the focus on the first 1,000 days is scientifically sound and historically grounded, it is time to reflect on its societal impact. We focus on its unintended negative consequences for parental well-being. Evidence for the importance of the first 1,000 days should drive collective action rather than reinforce individual blame. Parenting is not just a private matter; governments have a duty to provide parents with the resources to give their children the best start in life. En ligne : https://doi.org/10.1111/jcpp.70041 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568

Trajectories of parent criticism across treatment for youth self-harm / Madison AITKEN in Journal of Child Psychology and Psychiatry, 66-10 (October 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1449-1460 Titre : Trajectories of parent criticism across treatment for youth self-harm Type de document : texte imprimé Auteurs : Madison AITKEN, Auteur ; Florence PERQUIER, Auteur ; Bomi PARK, Auteur ; Daniela CARVALHO, Auteur ; Alexandra WRIGHT-HUGHES, Auteur ; David COTTRELL, Auteur ; Peter SZATMARI, Auteur Article en page(s) : p.1449-1460 Langues : Anglais (eng) Mots-clés : Parent–child relationships  adolescence  self-harm  psychotherapy  expressed emotion Index. décimale : PER Périodiques Résumé : Background Criticism from parents is a risk factor for poor youth mental health, including self-harm and limited response to psychosocial interventions. We identified trajectories of change in parent criticism across treatment for youth self-harm (suicide attempts and non-suicidal self-injury) and compared these trajectories on treatment outcomes. Methods This is a preregistered secondary analysis of data from the Self-harm Intervention: Family Therapy trial. Participants (N 831, 11 17 years; 89% girls, 11% boys; 84% White) were clinically referred for self-harm and randomly assigned to family therapy or usual care. A growth mixture model identified trajectories of parent self-reported criticism across baseline, 3, and 6 months. Trajectories were compared on youth self-harm, suicidal ideation, depression, and hopelessness, and parent mental distress (baseline, and change from baseline to 12 and 12 18 months). Results Four trajectories of parent criticism were identified: High and remaining elevated despite a small decrease (51.6%); sharply decreasing (7.6%); low/stable (37.2%); and increasing (3.6%). Youth with parents in the high with small decrease class had more severe baseline suicidal behavior. Treatment type was not related to criticism trajectory. Parent mental distress increased in the increasing criticism class. Youth with parents in the increasing class showed less improvement in suicidal ideation at 12-month follow-up compared to the high with small decrease and sharply decreasing classes. Conclusions Current treatments for youth self-harm may not reduce parent criticism to subclinical levels. Increasing parent criticism may forecast poorer response to a range of treatments for youth self-harm and be indicative of increases in parent mental distress. En ligne : https://doi.org/10.1111/jcpp.14144 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] Trajectories of parent criticism across treatment for youth self-harm [texte imprimé] / Madison AITKEN, Auteur ; Florence PERQUIER, Auteur ; Bomi PARK, Auteur ; Daniela CARVALHO, Auteur ; Alexandra WRIGHT-HUGHES, Auteur ; David COTTRELL, Auteur ; Peter SZATMARI, Auteur . - p.1449-1460. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1449-1460 Mots-clés : Parent–child relationships  adolescence  self-harm  psychotherapy  expressed emotion Index. décimale : PER Périodiques Résumé : Background Criticism from parents is a risk factor for poor youth mental health, including self-harm and limited response to psychosocial interventions. We identified trajectories of change in parent criticism across treatment for youth self-harm (suicide attempts and non-suicidal self-injury) and compared these trajectories on treatment outcomes. Methods This is a preregistered secondary analysis of data from the Self-harm Intervention: Family Therapy trial. Participants (N 831, 11 17 years; 89% girls, 11% boys; 84% White) were clinically referred for self-harm and randomly assigned to family therapy or usual care. A growth mixture model identified trajectories of parent self-reported criticism across baseline, 3, and 6 months. Trajectories were compared on youth self-harm, suicidal ideation, depression, and hopelessness, and parent mental distress (baseline, and change from baseline to 12 and 12 18 months). Results Four trajectories of parent criticism were identified: High and remaining elevated despite a small decrease (51.6%); sharply decreasing (7.6%); low/stable (37.2%); and increasing (3.6%). Youth with parents in the high with small decrease class had more severe baseline suicidal behavior. Treatment type was not related to criticism trajectory. Parent mental distress increased in the increasing criticism class. Youth with parents in the increasing class showed less improvement in suicidal ideation at 12-month follow-up compared to the high with small decrease and sharply decreasing classes. Conclusions Current treatments for youth self-harm may not reduce parent criticism to subclinical levels. Increasing parent criticism may forecast poorer response to a range of treatments for youth self-harm and be indicative of increases in parent mental distress. En ligne : https://doi.org/10.1111/jcpp.14144 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568

Sex differences and implications in outcome in children and adolescents at clinical high risk for psychosis / Jordina TOR in Journal of Child Psychology and Psychiatry, 66-10 (October 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1461-1472 Titre : Sex differences and implications in outcome in children and adolescents at clinical high risk for psychosis Type de document : texte imprimé Auteurs : Jordina TOR, Auteur ; Inmaculada BAEZA, Auteur ; Xavier ALVAREZ-SUBIELA, Auteur ; Marta RODRIGUEZ-PASCUAL, Auteur ; Daniel MUÑOZ-SAMONS, Auteur ; Anna SINTES-ESTEVEZ, Auteur ; Elena DE LA SERNA, Auteur ; Olga PUIG, Auteur ; Gisela SUGRANYES, Auteur ; Daniel ILZARBE, Auteur ; Josep Maria HARO, Auteur ; Montserrat DOLZ, Auteur Article en page(s) : p.1461-1472 Langues : Anglais (eng) Mots-clés : Sex differences  clinical high risk for psychosis  children and adolescents  psychosis  outcome Index. décimale : PER Périodiques Résumé : Background Sex differences have been identified in young adults along the psychosis continuum, but studies in children and adolescents are scarce. This study aimed to evaluate possible sex differences in clinical characteristics and outcomes in children and adolescents with clinical high risk for psychosis (CHR). Methods A naturalistic longitudinal cohort study assessed sociodemographics, CHR symptoms, functioning, and mood at baseline and at 18 months' follow-up in 221 CHR participants (154 females and 67 males) and 159 controls (93 females and 66 males). Regression analyses were performed to test baseline differences, and multinominal regression was used to test the implication of sex in outcome. Results Despite initial pairwise differences in attenuated positive symptoms, regression analyses failed to show sex differences in CHR symptoms when control group was added to the analyses. The interaction between sex and group significantly predicted depressive symptoms (B 2.907, p .040, 95% CI: [ 5.681, 0.133]) and caffeine use lifetime (OR 0.36, 95% CI: [0.138, 0.924], p .034). A significant interaction between age and sex showed that the older the age in females, the greater the probability of non-remission of CHR at follow-up, as compared to males (B 0.338, IC 95%: [0.123, 0.933], p .036), but no relevant associations with sex were found in psychosis outcome. Conclusions No sex-related differences in CHR symptoms were observed in a CHR children and adolescent population. Outcomes related to non-remission of CHR state in older females could reflect the greater prevalence of psychosis-like experiences in adolescent females. These results invite us to reconsider the usefulness of the current CHR criteria in young populations, especially if we do not take into account a gender perspective and how age might affect it. En ligne : https://doi.org/10.1111/jcpp.14148 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] Sex differences and implications in outcome in children and adolescents at clinical high risk for psychosis [texte imprimé] / Jordina TOR, Auteur ; Inmaculada BAEZA, Auteur ; Xavier ALVAREZ-SUBIELA, Auteur ; Marta RODRIGUEZ-PASCUAL, Auteur ; Daniel MUÑOZ-SAMONS, Auteur ; Anna SINTES-ESTEVEZ, Auteur ; Elena DE LA SERNA, Auteur ; Olga PUIG, Auteur ; Gisela SUGRANYES, Auteur ; Daniel ILZARBE, Auteur ; Josep Maria HARO, Auteur ; Montserrat DOLZ, Auteur . - p.1461-1472. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1461-1472 Mots-clés : Sex differences  clinical high risk for psychosis  children and adolescents  psychosis  outcome Index. décimale : PER Périodiques Résumé : Background Sex differences have been identified in young adults along the psychosis continuum, but studies in children and adolescents are scarce. This study aimed to evaluate possible sex differences in clinical characteristics and outcomes in children and adolescents with clinical high risk for psychosis (CHR). Methods A naturalistic longitudinal cohort study assessed sociodemographics, CHR symptoms, functioning, and mood at baseline and at 18 months' follow-up in 221 CHR participants (154 females and 67 males) and 159 controls (93 females and 66 males). Regression analyses were performed to test baseline differences, and multinominal regression was used to test the implication of sex in outcome. Results Despite initial pairwise differences in attenuated positive symptoms, regression analyses failed to show sex differences in CHR symptoms when control group was added to the analyses. The interaction between sex and group significantly predicted depressive symptoms (B 2.907, p .040, 95% CI: [ 5.681, 0.133]) and caffeine use lifetime (OR 0.36, 95% CI: [0.138, 0.924], p .034). A significant interaction between age and sex showed that the older the age in females, the greater the probability of non-remission of CHR at follow-up, as compared to males (B 0.338, IC 95%: [0.123, 0.933], p .036), but no relevant associations with sex were found in psychosis outcome. Conclusions No sex-related differences in CHR symptoms were observed in a CHR children and adolescent population. Outcomes related to non-remission of CHR state in older females could reflect the greater prevalence of psychosis-like experiences in adolescent females. These results invite us to reconsider the usefulness of the current CHR criteria in young populations, especially if we do not take into account a gender perspective and how age might affect it. En ligne : https://doi.org/10.1111/jcpp.14148 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568

Sexual and gender minority identity, peer victimization, and suicidality in adolescents: A mediation study using the ABCD Study / Sen LIU in Journal of Child Psychology and Psychiatry, 66-10 (October 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1473-1483 Titre : Sexual and gender minority identity, peer victimization, and suicidality in adolescents: A mediation study using the ABCD Study Type de document : texte imprimé Auteurs : Sen LIU, Auteur ; Devin ENGLISH, Auteur ; Yunyu XIAO, Auteur ; Yan LI, Auteur ; Li NIU, Auteur Article en page(s) : p.1473-1483 Langues : Anglais (eng) Mots-clés : Sexual and gender minority  suicidality  peer victimization  cyberbullying Index. décimale : PER Périodiques Résumé : Background Sexual and gender minority (SGM) youth are more susceptible to suicidal ideation and attempts compared to their heterosexual and cisgender peers. Yet, it is unclear how interpersonal and online victimization experiences account for the elevated suicide risks in this population. This study investigates the extent of peer and cyber victimization among SGM youth and its contribution to their higher risks of suicidal ideation and attempts longitudinally. Methods Data were from the first three waves of the Adolescent Brain Cognitive Development (ABCD) Study (5,596 9 10-year-old youth; 2,640 [47.2%] female; 3,107 [55.5%] non-Hispanic White). Youth reported sexual and gender identities and experiences of peer (overt, relational, reputational) and cyber victimization. Suicidal ideation and attempts were assessed using youth reports of Kiddie Schedule for Affective Disorders and Schizophrenia for DSM-5. We used mixed-effects logistic regression to quantify the association between SGM identity reported at waves 1 2 (9 11 years) and suicidal ideation and attempts at wave 3 (11 12 years) and longitudinal mediation analysis to determine whether peer and cyber victimization accounted for these associations. Results SGM youth were at greater risk for lifetime suicidal ideation (odds ratio [OR] 4.75, 95% CI 3.74 6.03), lifetime suicide attempts (OR 5.87, 95% CI 3.72 9.28), and current suicidal ideation or attempts (OR 4.94, 95% CI 3.19 7.68) compared to non-SGM youth. SGM youth experienced elevated peer (overt: ? 0.40, 95% CI 0.31 0.49; relational: ? 0.43, 95% CI 0.34 0.53; reputational: ? 0.51, 95% CI 0.42 0.60) and cyber victimization (OR 2.35, 95% CI 1.77 3.11). Around 22% 28% of the disparities in current suicidal ideation or attempts were mediated by peer or cyber victimization. Conclusions SGM youth are disproportionately affected by both interpersonal and online victimization, which are subsequently associated with their elevated suicide risks. Our findings underscore the urgent need for targeted interventions to foster safer school and online environments to reduce suicide among SGM youth. En ligne : https://doi.org/10.1111/jcpp.14155 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] Sexual and gender minority identity, peer victimization, and suicidality in adolescents: A mediation study using the ABCD Study [texte imprimé] / Sen LIU, Auteur ; Devin ENGLISH, Auteur ; Yunyu XIAO, Auteur ; Yan LI, Auteur ; Li NIU, Auteur . - p.1473-1483. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1473-1483 Mots-clés : Sexual and gender minority  suicidality  peer victimization  cyberbullying Index. décimale : PER Périodiques Résumé : Background Sexual and gender minority (SGM) youth are more susceptible to suicidal ideation and attempts compared to their heterosexual and cisgender peers. Yet, it is unclear how interpersonal and online victimization experiences account for the elevated suicide risks in this population. This study investigates the extent of peer and cyber victimization among SGM youth and its contribution to their higher risks of suicidal ideation and attempts longitudinally. Methods Data were from the first three waves of the Adolescent Brain Cognitive Development (ABCD) Study (5,596 9 10-year-old youth; 2,640 [47.2%] female; 3,107 [55.5%] non-Hispanic White). Youth reported sexual and gender identities and experiences of peer (overt, relational, reputational) and cyber victimization. Suicidal ideation and attempts were assessed using youth reports of Kiddie Schedule for Affective Disorders and Schizophrenia for DSM-5. We used mixed-effects logistic regression to quantify the association between SGM identity reported at waves 1 2 (9 11 years) and suicidal ideation and attempts at wave 3 (11 12 years) and longitudinal mediation analysis to determine whether peer and cyber victimization accounted for these associations. Results SGM youth were at greater risk for lifetime suicidal ideation (odds ratio [OR] 4.75, 95% CI 3.74 6.03), lifetime suicide attempts (OR 5.87, 95% CI 3.72 9.28), and current suicidal ideation or attempts (OR 4.94, 95% CI 3.19 7.68) compared to non-SGM youth. SGM youth experienced elevated peer (overt: ? 0.40, 95% CI 0.31 0.49; relational: ? 0.43, 95% CI 0.34 0.53; reputational: ? 0.51, 95% CI 0.42 0.60) and cyber victimization (OR 2.35, 95% CI 1.77 3.11). Around 22% 28% of the disparities in current suicidal ideation or attempts were mediated by peer or cyber victimization. Conclusions SGM youth are disproportionately affected by both interpersonal and online victimization, which are subsequently associated with their elevated suicide risks. Our findings underscore the urgent need for targeted interventions to foster safer school and online environments to reduce suicide among SGM youth. En ligne : https://doi.org/10.1111/jcpp.14155 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568

Scaling up home-visiting to promote early childhood development and prevent violence in Rwanda: a hybrid type-2 effectiveness-implementation trial / Candace J. BLACK in Journal of Child Psychology and Psychiatry, 66-10 (October 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1484-1499 Titre : Scaling up home-visiting to promote early childhood development and prevent violence in Rwanda: a hybrid type-2 effectiveness-implementation trial Type de document : texte imprimé Auteurs : Candace J. BLACK, Auteur ; Matias PLACENCIO-CASTRO, Auteur ; Gabriela PHEND, Auteur ; Jean Marie Vianney HAVUGIMANA, Auteur ; Grace UMULISA, Auteur ; Pacifique UWAMAHORO, Auteur ; Marie Gaudence NYIRAHABIMANA, Auteur ; Laura BOND, Auteur ; Kayla HERNANDEZ, Auteur ; Sarah K. G. JENSEN, Auteur ; Ursula KAJANI, Auteur ; Shauna M. MURRAY, Auteur ; Laura B. RAWLINGS, Auteur ; Vincent SEZIBERA, Auteur ; Theresa S. BETANCOURT, Auteur Article en page(s) : p.1484-1499 Langues : Anglais (eng) Mots-clés : Implementation science  implementation strategy  Hybrid Type-2 Trial  early child development  global health  violence prevention  father engagement  poverty  social protection  home-visiting Index. décimale : PER Périodiques Résumé : Background Children in impoverished families?especially those affected by violence?face risks to healthy development. In the years of strong economic recovery since the 1994 Genocide Against the Tutsi, the Rwandan Government has invested in early child development, social and child protection and violence prevention, but few strategies for scaling evidence-based interventions (EBIs) in these areas have been studied. Methods We present a Hybrid Type-2 Implementation-Effectiveness study of the PLAY Collaborative implementation strategy to engage government and other stakeholders in scaling Sugira Muryango (SM, ?Strong Family?) to families eligible for social protection in three rural districts. SM promotes nurturing care of children under three while reducing family violence. We assessed delivery quality (fidelity, competence) and perceptions of the PLAY Collaborative (e.g, feasibility, leadership, organisation, sustainability). An embedded trial of 538 households (778 caregivers, 555 children) tested SM effectiveness when delivered by child protection volunteers. Results Child protection volunteers delivered SM with high fidelity and competence that improved with time and routine supervision. The PLAY Collaborative was rated moderately to highly across implementation outcomes. The embedded trial revealed improvements in children's stimulation at home (d 0.20, 95% CI: 0.04 0.36) as caregivers involved them more in daily activities (d 0.37, 95% CI: 0.18 0.57) and provided more learning materials (d 0.37, 95% CI: 0.16 0.59). SM families increased stimulating care (e.g. singing, playing; d 0.26, 95% CI: 0.07 0.46); involved fathers more in caregiving (IRR 1.18, 95% CI: 1.03 1.37); reduced harsh discipline (OR 0.34, 95% CI: 0.14 0.82); and increased dietary diversity (d 0.25, 95% CI: 0.04 0.45). SM caregivers reported improved mental health (d 0.13, 95% CI: 0.26 to 0.01). SM households increased safe water storage (OR 3.14, 95% CI: 1.64 6.03) and water treatment (OR 3.56, 95% CI: 1.80 7.05) practices. Conclusions The PLAY Collaborative successfully overcame implementation barriers and maintained effectiveness across most outcomes while scaling delivery to N 8,745 families, highlighting the value of systematically investigating implementation strategies while scaling an EBI as integrated into existing social and child protection systems. En ligne : https://doi.org/10.1111/jcpp.14160 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] Scaling up home-visiting to promote early childhood development and prevent violence in Rwanda: a hybrid type-2 effectiveness-implementation trial [texte imprimé] / Candace J. BLACK, Auteur ; Matias PLACENCIO-CASTRO, Auteur ; Gabriela PHEND, Auteur ; Jean Marie Vianney HAVUGIMANA, Auteur ; Grace UMULISA, Auteur ; Pacifique UWAMAHORO, Auteur ; Marie Gaudence NYIRAHABIMANA, Auteur ; Laura BOND, Auteur ; Kayla HERNANDEZ, Auteur ; Sarah K. G. JENSEN, Auteur ; Ursula KAJANI, Auteur ; Shauna M. MURRAY, Auteur ; Laura B. RAWLINGS, Auteur ; Vincent SEZIBERA, Auteur ; Theresa S. BETANCOURT, Auteur . - p.1484-1499. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1484-1499 Mots-clés : Implementation science  implementation strategy  Hybrid Type-2 Trial  early child development  global health  violence prevention  father engagement  poverty  social protection  home-visiting Index. décimale : PER Périodiques Résumé : Background Children in impoverished families?especially those affected by violence?face risks to healthy development. In the years of strong economic recovery since the 1994 Genocide Against the Tutsi, the Rwandan Government has invested in early child development, social and child protection and violence prevention, but few strategies for scaling evidence-based interventions (EBIs) in these areas have been studied. Methods We present a Hybrid Type-2 Implementation-Effectiveness study of the PLAY Collaborative implementation strategy to engage government and other stakeholders in scaling Sugira Muryango (SM, ?Strong Family?) to families eligible for social protection in three rural districts. SM promotes nurturing care of children under three while reducing family violence. We assessed delivery quality (fidelity, competence) and perceptions of the PLAY Collaborative (e.g, feasibility, leadership, organisation, sustainability). An embedded trial of 538 households (778 caregivers, 555 children) tested SM effectiveness when delivered by child protection volunteers. Results Child protection volunteers delivered SM with high fidelity and competence that improved with time and routine supervision. The PLAY Collaborative was rated moderately to highly across implementation outcomes. The embedded trial revealed improvements in children's stimulation at home (d 0.20, 95% CI: 0.04 0.36) as caregivers involved them more in daily activities (d 0.37, 95% CI: 0.18 0.57) and provided more learning materials (d 0.37, 95% CI: 0.16 0.59). SM families increased stimulating care (e.g. singing, playing; d 0.26, 95% CI: 0.07 0.46); involved fathers more in caregiving (IRR 1.18, 95% CI: 1.03 1.37); reduced harsh discipline (OR 0.34, 95% CI: 0.14 0.82); and increased dietary diversity (d 0.25, 95% CI: 0.04 0.45). SM caregivers reported improved mental health (d 0.13, 95% CI: 0.26 to 0.01). SM households increased safe water storage (OR 3.14, 95% CI: 1.64 6.03) and water treatment (OR 3.56, 95% CI: 1.80 7.05) practices. Conclusions The PLAY Collaborative successfully overcame implementation barriers and maintained effectiveness across most outcomes while scaling delivery to N 8,745 families, highlighting the value of systematically investigating implementation strategies while scaling an EBI as integrated into existing social and child protection systems. En ligne : https://doi.org/10.1111/jcpp.14160 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568

Complex, low-intensity, individualised naturalistic developmental behavioural intervention in toddlers and pre-schoolers with autism spectrum disorder: The multicentre, observer-blind, parallel-group randomised-controlled A-FFIP trial / Christine M. FREITAG in Journal of Child Psychology and Psychiatry, 66-10 (October 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1500-1513 Titre : Complex, low-intensity, individualised naturalistic developmental behavioural intervention in toddlers and pre-schoolers with autism spectrum disorder: The multicentre, observer-blind, parallel-group randomised-controlled A-FFIP trial Type de document : texte imprimé Auteurs : Christine M. FREITAG, Auteur ; Marietta KIRCHNER, Auteur ; Lukas D. SAUER, Auteur ; Solvejg K. KLEBER, Auteur ; Leonie POLZER, Auteur ; Naisan RAJI, Auteur ; Christian LEMLER, Auteur ; Ulrike FRÖHLICH, Auteur ; Tomasz JARCZOK, Auteur ; Julia GEIßLER, Auteur ; Franziska RADTKE, Auteur ; Melanie RING, Auteur ; Veit ROESSNER, Auteur ; Regina TAURINES, Auteur ; Michelle NOTERDAEME, Auteur ; Karoline TEUFEL, Auteur ; Ziyon KIM, Auteur ; Janina KITZEROW-CLEVEN, Auteur Article en page(s) : p.1500-1513 Langues : Anglais (eng) Mots-clés : Naturalistic  developmental  behavioural  autism  social communication  repetitive behaviour  randomised-controlled Index. décimale : PER Périodiques Résumé : Background Naturalistic developmental behavioural interventions (NDBI) may improve social communication in toddlers/pre-school aged children with autism spectrum disorder (ASD). Here, we study efficacy of the low-intensity, complex NDBI ?Frankfurt Early Intervention Program for ASD? (A-FFIP) over 1 year by a confirmatory phase-III, prospective, randomised, controlled, parallel-group study with two treatment arms over four centres. Methods Main inclusion criteria: ASD (DSM-5), age 24 66 months, developmental quotient >30. Intervention: Manualised A-FFIP intervention. Control intervention: Early intervention as usual (EIAU). Primary outcome: Change in core ASD symptoms from baseline (T2) to immediate intervention endpoint at 12 months (T6) based on the blindly rated Brief Observation for Communication Change (BOSCC) total score. Statistical analysis: Mixed model for repeated measures with covariates baseline BOSCC-total, chronological age and centre. Results Between July 2018 and October 2021, N 134 children with ASD were randomly allocated to intervention (A-FFIP: n 68, EIAU: n 66). Groups did not differ at baseline, with a mean age of 49 (SD 10) months, a mean developmental age of 23.3 (SD 13.6) months and 26 (19.4%) females. The SARS-CoV-2 pandemic interfered severely with trial procedures. Intention-to-treat analysis in the primary analysis set, with at least one postbaseline BOSCC measure (A-FFIP n 64, EIAU n 60), did not find differences in the primary outcome by group (adjusted ES 0.06, 95% CI to 0.24 to 0.11). SARS-CoV2-related lockdown led to less improvement across groups. Secondary outcomes showed stronger improvements in parent-rated repetitive behaviour as well as parent- and teacher-rated executive functions for A-FFIP versus EIAU. Adverse events were comparable between groups. Conclusions The manualised NDBI program A-FFIP, which allows individually targeting six core basic abilities and five developmental domains related to longitudinal development in ASD, did not improve social communication, cognitive or behavioural outcomes beyond EIAU after 1 year, but may improve repetitive behaviour and executive function. En ligne : https://doi.org/10.1111/jcpp.14162 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] Complex, low-intensity, individualised naturalistic developmental behavioural intervention in toddlers and pre-schoolers with autism spectrum disorder: The multicentre, observer-blind, parallel-group randomised-controlled A-FFIP trial [texte imprimé] / Christine M. FREITAG, Auteur ; Marietta KIRCHNER, Auteur ; Lukas D. SAUER, Auteur ; Solvejg K. KLEBER, Auteur ; Leonie POLZER, Auteur ; Naisan RAJI, Auteur ; Christian LEMLER, Auteur ; Ulrike FRÖHLICH, Auteur ; Tomasz JARCZOK, Auteur ; Julia GEIßLER, Auteur ; Franziska RADTKE, Auteur ; Melanie RING, Auteur ; Veit ROESSNER, Auteur ; Regina TAURINES, Auteur ; Michelle NOTERDAEME, Auteur ; Karoline TEUFEL, Auteur ; Ziyon KIM, Auteur ; Janina KITZEROW-CLEVEN, Auteur . - p.1500-1513. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1500-1513 Mots-clés : Naturalistic  developmental  behavioural  autism  social communication  repetitive behaviour  randomised-controlled Index. décimale : PER Périodiques Résumé : Background Naturalistic developmental behavioural interventions (NDBI) may improve social communication in toddlers/pre-school aged children with autism spectrum disorder (ASD). Here, we study efficacy of the low-intensity, complex NDBI ?Frankfurt Early Intervention Program for ASD? (A-FFIP) over 1 year by a confirmatory phase-III, prospective, randomised, controlled, parallel-group study with two treatment arms over four centres. Methods Main inclusion criteria: ASD (DSM-5), age 24 66 months, developmental quotient >30. Intervention: Manualised A-FFIP intervention. Control intervention: Early intervention as usual (EIAU). Primary outcome: Change in core ASD symptoms from baseline (T2) to immediate intervention endpoint at 12 months (T6) based on the blindly rated Brief Observation for Communication Change (BOSCC) total score. Statistical analysis: Mixed model for repeated measures with covariates baseline BOSCC-total, chronological age and centre. Results Between July 2018 and October 2021, N 134 children with ASD were randomly allocated to intervention (A-FFIP: n 68, EIAU: n 66). Groups did not differ at baseline, with a mean age of 49 (SD 10) months, a mean developmental age of 23.3 (SD 13.6) months and 26 (19.4%) females. The SARS-CoV-2 pandemic interfered severely with trial procedures. Intention-to-treat analysis in the primary analysis set, with at least one postbaseline BOSCC measure (A-FFIP n 64, EIAU n 60), did not find differences in the primary outcome by group (adjusted ES 0.06, 95% CI to 0.24 to 0.11). SARS-CoV2-related lockdown led to less improvement across groups. Secondary outcomes showed stronger improvements in parent-rated repetitive behaviour as well as parent- and teacher-rated executive functions for A-FFIP versus EIAU. Adverse events were comparable between groups. Conclusions The manualised NDBI program A-FFIP, which allows individually targeting six core basic abilities and five developmental domains related to longitudinal development in ASD, did not improve social communication, cognitive or behavioural outcomes beyond EIAU after 1 year, but may improve repetitive behaviour and executive function. En ligne : https://doi.org/10.1111/jcpp.14162 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568

Autistic traits in childhood and post-traumatic stress disorder as young adults: a cohort study / Alice M. G. QUINTON in Journal of Child Psychology and Psychiatry, 66-10 (October 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1514-1525 Titre : Autistic traits in childhood and post-traumatic stress disorder as young adults: a cohort study Type de document : texte imprimé Auteurs : Alice M. G. QUINTON, Auteur ; Freya RUMBALL, Auteur ; Angelica RONALD, Auteur ; Helen L. FISHER, Auteur ; Louise ARSENEAULT, Auteur ; Francesca HAPPE, Auteur ; Andrea DANESE, Auteur Article en page(s) : p.1514-1525 Langues : Anglais (eng) Mots-clés : Autism  autism spectrum  trauma  PTSD  psychopathology Index. décimale : PER Périodiques Résumé : Background Despite the higher prevalence of childhood traumatic experiences and post-traumatic stress disorder (PTSD) in autistic adults, research on trauma-related psychopathology and autistic traits in young people is lacking. This study examined if high autistic traits in childhood predispose individuals to traumatic experiences, the development of PTSD and general psychopathology, and greater functional impairment by age 18, in both the general population and a subsample of trauma-exposed young people. Methods Data were utilised from the Environmental Risk (E-Risk) Longitudinal Twin Study, a nationally representative cohort of 2,232 same-sex twins born in 1994 1995 across England and Wales. Participants were a subset of children whose parents completed the Childhood Autism Spectrum Test (CAST), during assessments at ages 8, 9 and/or 12 years (N 1,504). We tested associations between autistic traits in childhood and age-18 reports of lifetime trauma exposure, lifetime PTSD diagnosis, general psychopathology (?p-factor?) and NEET status (?not in employment, education or training?). Analyses were conducted controlling for sex, family socioeconomic status (SES), intelligence quotient (IQ) and accounting for family clustering. Results Higher autistic traits in childhood were significantly associated with greater reports of lifetime trauma exposure (Odd Ratio [OR] 1.26, 95% Confidence Intervals [CI] 1.03; 1.54), lifetime PTSD diagnosis (OR 1.91, 95% CI 1.29; 2.82), general psychopathology (beta 3.22, 95% CI 1.84; 4.60) and NEET status (OR 1.48, 95% CI 1.05; 2.09) at age 18. Only the associations of autistic traits with PTSD and general psychopathology were robust to adjustment for potential confounders. Among trauma-exposed children, autistic traits were also significantly associated with lifetime PTSD diagnosis (OR 1.75, 95% CI 1.15; 2.68) and psychopathology (beta 3.36, 95% CI 0.68; 6.04) at age 18, but only the association with PTSD held when adjusted for confounders. Conclusions Our findings suggest a need to develop targeted assessments and evidence-based treatments for PTSD to meet the needs of children with high autistic traits. However, whether our findings extend to diagnosed autistic children requires further investigation. En ligne : https://doi.org/10.1111/jcpp.14163 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] Autistic traits in childhood and post-traumatic stress disorder as young adults: a cohort study [texte imprimé] / Alice M. G. QUINTON, Auteur ; Freya RUMBALL, Auteur ; Angelica RONALD, Auteur ; Helen L. FISHER, Auteur ; Louise ARSENEAULT, Auteur ; Francesca HAPPE, Auteur ; Andrea DANESE, Auteur . - p.1514-1525. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1514-1525 Mots-clés : Autism  autism spectrum  trauma  PTSD  psychopathology Index. décimale : PER Périodiques Résumé : Background Despite the higher prevalence of childhood traumatic experiences and post-traumatic stress disorder (PTSD) in autistic adults, research on trauma-related psychopathology and autistic traits in young people is lacking. This study examined if high autistic traits in childhood predispose individuals to traumatic experiences, the development of PTSD and general psychopathology, and greater functional impairment by age 18, in both the general population and a subsample of trauma-exposed young people. Methods Data were utilised from the Environmental Risk (E-Risk) Longitudinal Twin Study, a nationally representative cohort of 2,232 same-sex twins born in 1994 1995 across England and Wales. Participants were a subset of children whose parents completed the Childhood Autism Spectrum Test (CAST), during assessments at ages 8, 9 and/or 12 years (N 1,504). We tested associations between autistic traits in childhood and age-18 reports of lifetime trauma exposure, lifetime PTSD diagnosis, general psychopathology (?p-factor?) and NEET status (?not in employment, education or training?). Analyses were conducted controlling for sex, family socioeconomic status (SES), intelligence quotient (IQ) and accounting for family clustering. Results Higher autistic traits in childhood were significantly associated with greater reports of lifetime trauma exposure (Odd Ratio [OR] 1.26, 95% Confidence Intervals [CI] 1.03; 1.54), lifetime PTSD diagnosis (OR 1.91, 95% CI 1.29; 2.82), general psychopathology (beta 3.22, 95% CI 1.84; 4.60) and NEET status (OR 1.48, 95% CI 1.05; 2.09) at age 18. Only the associations of autistic traits with PTSD and general psychopathology were robust to adjustment for potential confounders. Among trauma-exposed children, autistic traits were also significantly associated with lifetime PTSD diagnosis (OR 1.75, 95% CI 1.15; 2.68) and psychopathology (beta 3.36, 95% CI 0.68; 6.04) at age 18, but only the association with PTSD held when adjusted for confounders. Conclusions Our findings suggest a need to develop targeted assessments and evidence-based treatments for PTSD to meet the needs of children with high autistic traits. However, whether our findings extend to diagnosed autistic children requires further investigation. En ligne : https://doi.org/10.1111/jcpp.14163 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568

Sudden gains in modular CBT for mental health disorders in children and young people with epilepsy / Alvin RICHARDS-BELLE in Journal of Child Psychology and Psychiatry, 66-10 (October 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1526-1538 Titre : Sudden gains in modular CBT for mental health disorders in children and young people with epilepsy Type de document : texte imprimé Auteurs : Alvin RICHARDS-BELLE, Auteur ; Daniela LINTON, Auteur ; J. Helen CROSS, Auteur ; Isobel HEYMAN, Auteur ; Emma DALRYMPLE, Auteur ; Bruce CHORPITA, Auteur ; Sophia VARADKAR, Auteur ; Mariam SHAH, Auteur ; Mice Study GROUP, Auteur ; Roz SHAFRAN, Auteur ; Sophie BENNETT, Auteur Article en page(s) : p.1526-1538 Langues : Anglais (eng) Mots-clés : Children and young people  epilepsy  long-term conditions  mental health disorders  CBT Index. décimale : PER Périodiques Résumé : Background Sudden gains (rapid, large, stable improvements in symptoms) are common in psychological therapy and are associated with favourable outcomes, but no studies have investigated sudden gains in children and young people (CYP) with a chronic physical condition. Methods Within-group study nested in the Mental Health Intervention for Children with Epilepsy (MICE) randomised trial of modular cognitive-behavioural therapy for CYP with epilepsy, utilising goal-based outcomes (GBOs) and standardised session-by-session measures (including the brief parental self-efficacy scale and Strengths and Difficulties Questionnaire [SDQ] session-by-session measure). The occurrence and potential predictors of sudden gains, and the association of sudden gains with outcomes at final session and follow-up were investigated using multivariable logistic and linear regression. Results Among 147 participants (mean age: 10.4 years, 49% female) and across nine measures, 39% experienced between two and four sudden gains, most frequently on the mean GBO (occurrence, 44.9%). Characteristics such as intellectual disability, pretreatment scores and the number of sessions received were associated with significantly greater odds of sudden gains in some measures, whereas nonwhite ethnicity and nonemployment of the primary caregiver were associated with reduced odds. Sudden gains were associated with favourable final-session scores for mean GBO (GBO, adjusted mean difference [aMD]: 0.9, 95% CI: 0.3 to 1.6, p = .004, D 0.63), parental self-efficacy (aMD: 1.2, 95% CI, 0.1 to 2.4, p .027, D 0.37) and the SDQ session-by-session measure (aMD: -1.7, 95% CI, 3.0 to 0.3, p .014, D -0.44), but not with 6-month adjusted SDQ total difficulties scores. Conclusions Sudden gains were common in this population, occurring most frequently on personalised measures, and were associated with favourable final-session scores. Personalised measures taken at each session with a focus on sudden gains may be a useful adjunct to treatment. Future research and clinical practice should investigate how to increase the occurrence of sudden gains in CYP with long-term conditions receiving psychological therapy. En ligne : https://doi.org/10.1111/jcpp.14164 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] Sudden gains in modular CBT for mental health disorders in children and young people with epilepsy [texte imprimé] / Alvin RICHARDS-BELLE, Auteur ; Daniela LINTON, Auteur ; J. Helen CROSS, Auteur ; Isobel HEYMAN, Auteur ; Emma DALRYMPLE, Auteur ; Bruce CHORPITA, Auteur ; Sophia VARADKAR, Auteur ; Mariam SHAH, Auteur ; Mice Study GROUP, Auteur ; Roz SHAFRAN, Auteur ; Sophie BENNETT, Auteur . - p.1526-1538. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1526-1538 Mots-clés : Children and young people  epilepsy  long-term conditions  mental health disorders  CBT Index. décimale : PER Périodiques Résumé : Background Sudden gains (rapid, large, stable improvements in symptoms) are common in psychological therapy and are associated with favourable outcomes, but no studies have investigated sudden gains in children and young people (CYP) with a chronic physical condition. Methods Within-group study nested in the Mental Health Intervention for Children with Epilepsy (MICE) randomised trial of modular cognitive-behavioural therapy for CYP with epilepsy, utilising goal-based outcomes (GBOs) and standardised session-by-session measures (including the brief parental self-efficacy scale and Strengths and Difficulties Questionnaire [SDQ] session-by-session measure). The occurrence and potential predictors of sudden gains, and the association of sudden gains with outcomes at final session and follow-up were investigated using multivariable logistic and linear regression. Results Among 147 participants (mean age: 10.4 years, 49% female) and across nine measures, 39% experienced between two and four sudden gains, most frequently on the mean GBO (occurrence, 44.9%). Characteristics such as intellectual disability, pretreatment scores and the number of sessions received were associated with significantly greater odds of sudden gains in some measures, whereas nonwhite ethnicity and nonemployment of the primary caregiver were associated with reduced odds. Sudden gains were associated with favourable final-session scores for mean GBO (GBO, adjusted mean difference [aMD]: 0.9, 95% CI: 0.3 to 1.6, p = .004, D 0.63), parental self-efficacy (aMD: 1.2, 95% CI, 0.1 to 2.4, p .027, D 0.37) and the SDQ session-by-session measure (aMD: -1.7, 95% CI, 3.0 to 0.3, p .014, D -0.44), but not with 6-month adjusted SDQ total difficulties scores. Conclusions Sudden gains were common in this population, occurring most frequently on personalised measures, and were associated with favourable final-session scores. Personalised measures taken at each session with a focus on sudden gains may be a useful adjunct to treatment. Future research and clinical practice should investigate how to increase the occurrence of sudden gains in CYP with long-term conditions receiving psychological therapy. En ligne : https://doi.org/10.1111/jcpp.14164 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568

Early social interactions and young school-aged children's behavioral problems: Converging evidence from theory- and data-driven approaches / Jiahao LIANG in Journal of Child Psychology and Psychiatry, 66-10 (October 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1539-1550 Titre : Early social interactions and young school-aged children's behavioral problems: Converging evidence from theory- and data-driven approaches Type de document : texte imprimé Auteurs : Jiahao LIANG, Auteur ; Yiji WANG, Auteur Article en page(s) : p.1539-1550 Langues : Anglais (eng) Mots-clés : Social interactions  internalizing problems  externalizing problems  machine learning  structural equation modeling Index. décimale : PER Périodiques Résumé : Background Although prior studies have established the relation between social interactions and behavioral adjustment, it remains unclear whether aspects of early social interactions are uniquely related to behavioral problems and the relative importance of each in predicting internalizing and externalizing problems. Using traditional theory-driven and novel data-driven perspectives, this longitudinal study simultaneously evaluated the role of preschool mother?child, teacher ?child, and peer interactions in predicting internalizing and externalizing problems in early grade school. Methods At 36 months, the quality of children's social interactions with mothers, teachers, and peers were observed and coded (N 1,028). Mothers later reported children's internalizing and externalizing problems in first grade. Theory-driven structural equation modeling (SEM) and data-driven machine learning models (i.e., random forests and support vector machines) were performed separately for data analysis. Results The results showed that machine learning models, particularly support vector machines, outperformed SEM in model performance. Regarding the relative importance of predictors, SEM suggested that indicators of early peer interactions uniquely predicted behavioral problems in early grade school when those of teacher?child and mother?child interactions were considered simultaneously. Machine learning models consistently demonstrated that indicators of early peer interactions had the highest feature importance and were among the highest ranking predictors of children's subsequent behavioral adjustment. Conclusions The findings contribute converging evidence from theory- and data-driven approaches to better understand the longitudinal associations between preschoolers' social interactions and later behavioral adjustments in early grade school. En ligne : https://doi.org/10.1111/jcpp.14166 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] Early social interactions and young school-aged children's behavioral problems: Converging evidence from theory- and data-driven approaches [texte imprimé] / Jiahao LIANG, Auteur ; Yiji WANG, Auteur . - p.1539-1550. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1539-1550 Mots-clés : Social interactions  internalizing problems  externalizing problems  machine learning  structural equation modeling Index. décimale : PER Périodiques Résumé : Background Although prior studies have established the relation between social interactions and behavioral adjustment, it remains unclear whether aspects of early social interactions are uniquely related to behavioral problems and the relative importance of each in predicting internalizing and externalizing problems. Using traditional theory-driven and novel data-driven perspectives, this longitudinal study simultaneously evaluated the role of preschool mother?child, teacher ?child, and peer interactions in predicting internalizing and externalizing problems in early grade school. Methods At 36 months, the quality of children's social interactions with mothers, teachers, and peers were observed and coded (N 1,028). Mothers later reported children's internalizing and externalizing problems in first grade. Theory-driven structural equation modeling (SEM) and data-driven machine learning models (i.e., random forests and support vector machines) were performed separately for data analysis. Results The results showed that machine learning models, particularly support vector machines, outperformed SEM in model performance. Regarding the relative importance of predictors, SEM suggested that indicators of early peer interactions uniquely predicted behavioral problems in early grade school when those of teacher?child and mother?child interactions were considered simultaneously. Machine learning models consistently demonstrated that indicators of early peer interactions had the highest feature importance and were among the highest ranking predictors of children's subsequent behavioral adjustment. Conclusions The findings contribute converging evidence from theory- and data-driven approaches to better understand the longitudinal associations between preschoolers' social interactions and later behavioral adjustments in early grade school. En ligne : https://doi.org/10.1111/jcpp.14166 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568

Combined effects of prenatal ozone exposure and school/neighborhood environments on youth brain, cognition, and psychotic-like experiences / Tianjiao KONG in Journal of Child Psychology and Psychiatry, 66-10 (October 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1551-1562 Titre : Combined effects of prenatal ozone exposure and school/neighborhood environments on youth brain, cognition, and psychotic-like experiences Type de document : texte imprimé Auteurs : Tianjiao KONG, Auteur ; Yumeng YANG, Auteur ; Feng JI, Auteur ; Jia LIU, Auteur ; Ran LIU, Auteur ; Liang LUO, Auteur Article en page(s) : p.1551-1562 Langues : Anglais (eng) Mots-clés : Prenatal ozone exposure  psychosocial environments  combined effects  limbic system development  cognition  psychotic-like experiences Index. décimale : PER Périodiques Résumé : Background Humans are inevitably exposed to multiple physical and social environmental risk factors, potentially contributing to psychiatric problems and cognitive deficits; however, the combined effects of prenatal air pollution and psychosocial environments on youth remain unclear. This longitudinal study aimed to examine how prenatal ozone exposure interacts with psychosocial environments at 9 10 years to affect adolescent limbic system development, cognition, and psychotic-like experiences (PLEs) at 11 13 years. Methods We analyzed data from 6,778 participants in the Adolescent Brain Cognitive Development (ABCD) Study? at two time points (baseline: 9 10 years and 2-year follow-up). Prenatal ozone exposure was calculated as a 9-month average of daily exposure estimates based on birth year and address. Social environmental factors included school environment and neighborhood safety at both time points. Structural MRI measures included bilateral amygdala and hippocampus volumes at both time points. Behavioral data consisted of cognition and PLEs scores at both time points. Moderation and moderated mediation models with cluster-robust standard errors were constructed to examine the effects, controlling for covariates. Results Children who were prenatally exposed to greater ozone and had a more unfavorable school environment exhibited a smaller increase in left hippocampal volume, leading to poorer cognition and more PLEs. Moreover, children who were prenatally exposed to greater ozone and lived in a more unsafe neighborhood had a larger increase in right amygdala volume. Conclusions This longitudinal study is the first to demonstrate the combined effects of prenatal ozone pollutant and adverse social environments in childhood on youth psychotic-like experiences and cognition, highlighting the limbic system as an important neural mechanism underlying the effects. En ligne : https://doi.org/10.1111/jcpp.14167 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] Combined effects of prenatal ozone exposure and school/neighborhood environments on youth brain, cognition, and psychotic-like experiences [texte imprimé] / Tianjiao KONG, Auteur ; Yumeng YANG, Auteur ; Feng JI, Auteur ; Jia LIU, Auteur ; Ran LIU, Auteur ; Liang LUO, Auteur . - p.1551-1562. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1551-1562 Mots-clés : Prenatal ozone exposure  psychosocial environments  combined effects  limbic system development  cognition  psychotic-like experiences Index. décimale : PER Périodiques Résumé : Background Humans are inevitably exposed to multiple physical and social environmental risk factors, potentially contributing to psychiatric problems and cognitive deficits; however, the combined effects of prenatal air pollution and psychosocial environments on youth remain unclear. This longitudinal study aimed to examine how prenatal ozone exposure interacts with psychosocial environments at 9 10 years to affect adolescent limbic system development, cognition, and psychotic-like experiences (PLEs) at 11 13 years. Methods We analyzed data from 6,778 participants in the Adolescent Brain Cognitive Development (ABCD) Study? at two time points (baseline: 9 10 years and 2-year follow-up). Prenatal ozone exposure was calculated as a 9-month average of daily exposure estimates based on birth year and address. Social environmental factors included school environment and neighborhood safety at both time points. Structural MRI measures included bilateral amygdala and hippocampus volumes at both time points. Behavioral data consisted of cognition and PLEs scores at both time points. Moderation and moderated mediation models with cluster-robust standard errors were constructed to examine the effects, controlling for covariates. Results Children who were prenatally exposed to greater ozone and had a more unfavorable school environment exhibited a smaller increase in left hippocampal volume, leading to poorer cognition and more PLEs. Moreover, children who were prenatally exposed to greater ozone and lived in a more unsafe neighborhood had a larger increase in right amygdala volume. Conclusions This longitudinal study is the first to demonstrate the combined effects of prenatal ozone pollutant and adverse social environments in childhood on youth psychotic-like experiences and cognition, highlighting the limbic system as an important neural mechanism underlying the effects. En ligne : https://doi.org/10.1111/jcpp.14167 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568

Psychoneuroendocrine stress response in female and male youth with major depressive disorder / Anka BERNHARD in Journal of Child Psychology and Psychiatry, 66-10 (October 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1563-1576 Titre : Psychoneuroendocrine stress response in female and male youth with major depressive disorder Type de document : texte imprimé Auteurs : Anka BERNHARD, Auteur ; Nikola FANN, Auteur ; Andreas G. CHIOCCHETTI, Auteur ; Katharina ACKERMANN, Auteur ; Anne MARTINELLI, Auteur ; Christine M. FREITAG, Auteur Article en page(s) : p.1563-1576 Langues : Anglais (eng) Mots-clés : Major depressive disorder  adolescence  stress response  cortisol  testosterone  oxytocin Index. décimale : PER Périodiques Résumé : Background Exposure to psychosocial stress is one of the strongest risk factors for major depressive disorder (MDD) in youth, but underlying neurobiological mechanisms are poorly understood. Previous studies on the neuroendocrine stress response in youth with MDD are scarce, limited to cortisol, and rarely considered sex differences. Due to puberty-associated neuroendocrine transitions increasing the risk for MDD onset in adolescence, this study aimed to investigate sex-specific stress responses of stress and sex hormones as well as of neuropeptides. Methods In 103 pubertal youths with MDD and 72 healthy controls (HCs; 62% females, 12 18 years), psychological stress as well as salivary cortisol, testosterone, and oxytocin reactivity to a standardized psychosocial stress test (Trier Social Stress Test, TSST) were assessed. Effects of group and sex, and their interactions were analyzed using hierarchical linear models, while controlling for potentially confounding factors (such as age and pubertal status). Results Females and males with MDD showed a stronger psychological stress response than HCs. In contrast, both female and male youth with MDD showed blunted cortisol, testosterone, and oxytocin stress responses compared to HCs. In addition, baseline testosterone was elevated in MDD compared to HCs. Conclusions Results indicate a discrepant stress reactivity in youth with MDD, with increased psychological, but decreased neuroendocrine responses to psychosocial stress. Blunted neuroendocrine stress responses in youth with MDD were found across different neuroendocrine systems and in both females and males with MDD. These novel findings point to a fundamentally changed stress response in youth with MDD irrespective of sex, which may influence successful stress regulation in the affected adolescents. En ligne : https://doi.org/10.1111/jcpp.14168 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] Psychoneuroendocrine stress response in female and male youth with major depressive disorder [texte imprimé] / Anka BERNHARD, Auteur ; Nikola FANN, Auteur ; Andreas G. CHIOCCHETTI, Auteur ; Katharina ACKERMANN, Auteur ; Anne MARTINELLI, Auteur ; Christine M. FREITAG, Auteur . - p.1563-1576. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1563-1576 Mots-clés : Major depressive disorder  adolescence  stress response  cortisol  testosterone  oxytocin Index. décimale : PER Périodiques Résumé : Background Exposure to psychosocial stress is one of the strongest risk factors for major depressive disorder (MDD) in youth, but underlying neurobiological mechanisms are poorly understood. Previous studies on the neuroendocrine stress response in youth with MDD are scarce, limited to cortisol, and rarely considered sex differences. Due to puberty-associated neuroendocrine transitions increasing the risk for MDD onset in adolescence, this study aimed to investigate sex-specific stress responses of stress and sex hormones as well as of neuropeptides. Methods In 103 pubertal youths with MDD and 72 healthy controls (HCs; 62% females, 12 18 years), psychological stress as well as salivary cortisol, testosterone, and oxytocin reactivity to a standardized psychosocial stress test (Trier Social Stress Test, TSST) were assessed. Effects of group and sex, and their interactions were analyzed using hierarchical linear models, while controlling for potentially confounding factors (such as age and pubertal status). Results Females and males with MDD showed a stronger psychological stress response than HCs. In contrast, both female and male youth with MDD showed blunted cortisol, testosterone, and oxytocin stress responses compared to HCs. In addition, baseline testosterone was elevated in MDD compared to HCs. Conclusions Results indicate a discrepant stress reactivity in youth with MDD, with increased psychological, but decreased neuroendocrine responses to psychosocial stress. Blunted neuroendocrine stress responses in youth with MDD were found across different neuroendocrine systems and in both females and males with MDD. These novel findings point to a fundamentally changed stress response in youth with MDD irrespective of sex, which may influence successful stress regulation in the affected adolescents. En ligne : https://doi.org/10.1111/jcpp.14168 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568

Emotional burden in school as a source of mental health problems associated with ADHD and/or autism: Development and validation of a new co-produced self-report measure / Steve LUKITO in Journal of Child Psychology and Psychiatry, 66-10 (October 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1577-1592 Titre : Emotional burden in school as a source of mental health problems associated with ADHD and/or autism: Development and validation of a new co-produced self-report measure Type de document : texte imprimé Auteurs : Steve LUKITO, Auteur ; Susie CHANDLER, Auteur ; Myrofora KAKOULIDOU, Auteur ; Kirsty GRIFFITHS, Auteur ; Anna WYATT, Auteur ; Eloise FUNNELL, Auteur ; Georgia PAVLOPOULOU, Auteur ; Sylvan BAKER, Auteur ; Daniel STAHL, Auteur ; Edmund SONUGA-BARKE, Auteur ; R. E. Star team THE, Auteur Article en page(s) : p.1577-1592 Langues : Anglais (eng) Mots-clés : Autism  attention-deficit/hyperactivity disorder  emotional burden  emotion dysregulation  psychometrics Index. décimale : PER Périodiques Résumé : Background Mental health problems are elevated in adolescents with ADHD and/or autism. Emotion regulation deficits (ERD) have been hypothesised as a key driver of such difficulties. The Regulating Emotions ? Strengthening Adolescent Resilience (RE-STAR) programme is examining an alternative pathway from neurodivergence to mental health problems, mediated by elevated emotional burden (EB) resulting from the interplay of increased exposure and an unusually intense emotional reaction to commonly upsetting events (CUEs). We present the development and application of the My Emotions in School Inventory (MESI), a self-report questionnaire co-produced with neurodivergent young people, focusing on EB in schools ? a setting thought to be of particular significance in this regard. Methods The MESI, containing 25 school-related CUEs rated on their frequency and the intensity of negative emotions they induce, was completed by secondary school students meeting symptom cut-offs on clinically validated scales of ADHD (n 100), autism (n 104), ADHD+autism (n 79) and neurotypical students (n 452). Psychometric properties were examined. The ability of the MESI to discriminate adolescents with ADHD and/or autism from neurotypical adolescents, and to predict depression and anxiety, independently of ERD, was explored. Results Adolescents in the ADHD and/or autism groups experienced higher CUE frequency and intensity of reaction than their neurotypical peers. Overall levels of EB, most robustly indexed by 24 MESI CUEs, were higher in the three neurodivergent groups, though they did not differ from each other. EB in the autism and ADHD groups was generated by distinctly different CUEs. EB and ERD each contributed independently to the prediction of higher depression or anxiety. Conclusions Our findings illustrate the potential value of the MESI as an instrument to measure the contribution of EB alongside ERD in relation to adolescent mental health risks in ADHD and/or autism. Future studies need to investigate its role longitudinally. En ligne : https://doi.org/10.1111/jcpp.70003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] Emotional burden in school as a source of mental health problems associated with ADHD and/or autism: Development and validation of a new co-produced self-report measure [texte imprimé] / Steve LUKITO, Auteur ; Susie CHANDLER, Auteur ; Myrofora KAKOULIDOU, Auteur ; Kirsty GRIFFITHS, Auteur ; Anna WYATT, Auteur ; Eloise FUNNELL, Auteur ; Georgia PAVLOPOULOU, Auteur ; Sylvan BAKER, Auteur ; Daniel STAHL, Auteur ; Edmund SONUGA-BARKE, Auteur ; R. E. Star team THE, Auteur . - p.1577-1592. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1577-1592 Mots-clés : Autism  attention-deficit/hyperactivity disorder  emotional burden  emotion dysregulation  psychometrics Index. décimale : PER Périodiques Résumé : Background Mental health problems are elevated in adolescents with ADHD and/or autism. Emotion regulation deficits (ERD) have been hypothesised as a key driver of such difficulties. The Regulating Emotions ? Strengthening Adolescent Resilience (RE-STAR) programme is examining an alternative pathway from neurodivergence to mental health problems, mediated by elevated emotional burden (EB) resulting from the interplay of increased exposure and an unusually intense emotional reaction to commonly upsetting events (CUEs). We present the development and application of the My Emotions in School Inventory (MESI), a self-report questionnaire co-produced with neurodivergent young people, focusing on EB in schools ? a setting thought to be of particular significance in this regard. Methods The MESI, containing 25 school-related CUEs rated on their frequency and the intensity of negative emotions they induce, was completed by secondary school students meeting symptom cut-offs on clinically validated scales of ADHD (n 100), autism (n 104), ADHD+autism (n 79) and neurotypical students (n 452). Psychometric properties were examined. The ability of the MESI to discriminate adolescents with ADHD and/or autism from neurotypical adolescents, and to predict depression and anxiety, independently of ERD, was explored. Results Adolescents in the ADHD and/or autism groups experienced higher CUE frequency and intensity of reaction than their neurotypical peers. Overall levels of EB, most robustly indexed by 24 MESI CUEs, were higher in the three neurodivergent groups, though they did not differ from each other. EB in the autism and ADHD groups was generated by distinctly different CUEs. EB and ERD each contributed independently to the prediction of higher depression or anxiety. Conclusions Our findings illustrate the potential value of the MESI as an instrument to measure the contribution of EB alongside ERD in relation to adolescent mental health risks in ADHD and/or autism. Future studies need to investigate its role longitudinally. En ligne : https://doi.org/10.1111/jcpp.70003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568

Research Review: Help-seeking intentions, behaviors, and barriers in college students – a systematic review and meta-analysis / Ruiying ZHAO in Journal of Child Psychology and Psychiatry, 66-10 (October 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1593-1605 Titre : Research Review: Help-seeking intentions, behaviors, and barriers in college students – a systematic review and meta-analysis Type de document : texte imprimé Auteurs : Ruiying ZHAO, Auteur ; Yagmur AMANVERMEZ, Auteur ; Julia PEI, Auteur ; Franchesca CASTRO-RAMIREZ, Auteur ; Charlene RAPSEY, Auteur ; Claudia GARCIA, Auteur ; David D. EBERT, Auteur ; Josep Maria HARO, Auteur ; Liviu A. FODOR, Auteur ; Oana A. DAVID, Auteur ; Osiris RANKIN, Auteur ; Sook Ning CHUA, Auteur ; Vania MARTÍNEZ, Auteur ; Ronny BRUFFAERTS, Auteur ; Ronald C. KESSLER, Auteur ; Pim CUIJPERS, Auteur Article en page(s) : p.1593-1605 Langues : Anglais (eng) Mots-clés : Help-seeking  college students  help-seeking behaviors  help-seeking intentions  mental health barriers Index. décimale : PER Périodiques Résumé : Background The prevalence of mental health problems among college students has increased over the past decade. Even when mental health services are available, many students still struggle to access these services. This systematic review and meta-analysis aimed to identify the rates at which students actively seek or consider using formal help and to determine the main reasons for not seeking help. Methods A comprehensive literature search was conducted on PubMed, PsycINFO, and Embase to identify studies on help-seeking behaviors, intentions, and barriers to help-seeking among college students with mental health problems. Random effect models were used to calculate the pooled proportions. Results Of the 8,919 identified studies, 62 met the inclusion criteria and were included (n 53 on help-seeking behaviors, n 21 on help-seeking intentions, and n 14 on treatment barriers). The pooled prevalence of active help-seeking behaviors was 28% (179,915/435,768 individuals; 95% CI: 23% 33%, I2 99.6%), and the aggregated prevalence of help-seeking intentions was 41% (62,456/80161 individuals; 95% CI: 26% 58%, I2 99.8%). Common barriers reported by students included a preference to address issues on their own, time constraints, insufficient knowledge of accessible resources, and a perceived lack of need for professional help. Conclusions The findings highlight the gap between the mental health needs of the students and their actual help-seeking rates. Although personal barriers are common, systemic or contextual challenges also affect college students' help-seeking behaviors. En ligne : https://doi.org/10.1111/jcpp.14145 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] Research Review: Help-seeking intentions, behaviors, and barriers in college students – a systematic review and meta-analysis [texte imprimé] / Ruiying ZHAO, Auteur ; Yagmur AMANVERMEZ, Auteur ; Julia PEI, Auteur ; Franchesca CASTRO-RAMIREZ, Auteur ; Charlene RAPSEY, Auteur ; Claudia GARCIA, Auteur ; David D. EBERT, Auteur ; Josep Maria HARO, Auteur ; Liviu A. FODOR, Auteur ; Oana A. DAVID, Auteur ; Osiris RANKIN, Auteur ; Sook Ning CHUA, Auteur ; Vania MARTÍNEZ, Auteur ; Ronny BRUFFAERTS, Auteur ; Ronald C. KESSLER, Auteur ; Pim CUIJPERS, Auteur . - p.1593-1605. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1593-1605 Mots-clés : Help-seeking  college students  help-seeking behaviors  help-seeking intentions  mental health barriers Index. décimale : PER Périodiques Résumé : Background The prevalence of mental health problems among college students has increased over the past decade. Even when mental health services are available, many students still struggle to access these services. This systematic review and meta-analysis aimed to identify the rates at which students actively seek or consider using formal help and to determine the main reasons for not seeking help. Methods A comprehensive literature search was conducted on PubMed, PsycINFO, and Embase to identify studies on help-seeking behaviors, intentions, and barriers to help-seeking among college students with mental health problems. Random effect models were used to calculate the pooled proportions. Results Of the 8,919 identified studies, 62 met the inclusion criteria and were included (n 53 on help-seeking behaviors, n 21 on help-seeking intentions, and n 14 on treatment barriers). The pooled prevalence of active help-seeking behaviors was 28% (179,915/435,768 individuals; 95% CI: 23% 33%, I2 99.6%), and the aggregated prevalence of help-seeking intentions was 41% (62,456/80161 individuals; 95% CI: 26% 58%, I2 99.8%). Common barriers reported by students included a preference to address issues on their own, time constraints, insufficient knowledge of accessible resources, and a perceived lack of need for professional help. Conclusions The findings highlight the gap between the mental health needs of the students and their actual help-seeking rates. Although personal barriers are common, systemic or contextual challenges also affect college students' help-seeking behaviors. En ligne : https://doi.org/10.1111/jcpp.14145 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568

Examining the association between placental malperfusion assessed by histopathological examination and child and adolescent neurodevelopment: a systematic review / Noha IBRAHIM in Journal of Child Psychology and Psychiatry, 66-10 (October 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1606-1620 Titre : Examining the association between placental malperfusion assessed by histopathological examination and child and adolescent neurodevelopment: a systematic review Type de document : texte imprimé Auteurs : Noha IBRAHIM, Auteur ; Sydni A. WEISSGOLD, Auteur ; Lucy BRINK, Auteur ; Ibtihal MAHGOUB, Auteur ; Ben CARTER, Auteur ; Vaheshta SETHNA, Auteur ; Hein ODENDAAL, Auteur Article en page(s) : p.1606-1620 Langues : Anglais (eng) Mots-clés : Placental vascular malperfusion  placental vascular under-perfusion  placental histopathology  neurodevelopmental disorders  systematic review Index. décimale : PER Périodiques Résumé : Background Placental malperfusion, categorised into maternal vascular malperfusion (MVM) and foetal vascular malperfusion (FVM), is a main placental pathology known to affect placental functioning and offspring outcomes. The aim of this review is to evaluate the association between exposure to placental malperfusion and offspring neurodevelopment from birth to 18 years of age. Methods Following the registered protocol on Prospero, Medline, Cochrane, CINHAL, Embase and PsycINFO databases were searched systematically from inception to 01/11/2023. Included were publications examining exposure to placental malperfusion detected on histopathological examination and clinically measured neurodevelopmental outcomes. Publications on multi-pregnancies or animals, exposure to malformations, surgical or medical interventions, review and opinion articles, or those not translated to English, were excluded. Grey literature search and forward and backward citation chaining were performed. The Joanna Briggs Institute's checklists were used for quality assessment. Three studies were pooled using percentages of adjusted associations. Results Nine observational studies fulfilled the eligibility criteria. The included neurodevelopmental outcomes were assessed from 5 days to 8 years when age of assessment is reported. Four publications showed an association between exposure to MVM and poor neurodevelopment at 10 40 months and 8 years, however, no association was observed when examining preterm infants up to 24 months. Conversely, in the six studies examining exposure to FVM, FVM association with neurodevelopmental disorders was reported in two studies looking at preterm infants assessed at 24 months and 8 years and better neurodevelopmental scores in other two studies at 10 40 months. Conclusions The pattern of association between MVM and FVM with neurodevelopmental outcomes varied among the included studies. Clinical and methodological heterogeneities and poor reporting of relevant populations' characteristics hindered full understanding of the results. Methodologically rigorous research is required to help utilise histopathological findings of placental malperfusion in predicting offspring's neurodevelopmental outcomes. En ligne : https://doi.org/10.1111/jcpp.14152 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] Examining the association between placental malperfusion assessed by histopathological examination and child and adolescent neurodevelopment: a systematic review [texte imprimé] / Noha IBRAHIM, Auteur ; Sydni A. WEISSGOLD, Auteur ; Lucy BRINK, Auteur ; Ibtihal MAHGOUB, Auteur ; Ben CARTER, Auteur ; Vaheshta SETHNA, Auteur ; Hein ODENDAAL, Auteur . - p.1606-1620. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1606-1620 Mots-clés : Placental vascular malperfusion  placental vascular under-perfusion  placental histopathology  neurodevelopmental disorders  systematic review Index. décimale : PER Périodiques Résumé : Background Placental malperfusion, categorised into maternal vascular malperfusion (MVM) and foetal vascular malperfusion (FVM), is a main placental pathology known to affect placental functioning and offspring outcomes. The aim of this review is to evaluate the association between exposure to placental malperfusion and offspring neurodevelopment from birth to 18 years of age. Methods Following the registered protocol on Prospero, Medline, Cochrane, CINHAL, Embase and PsycINFO databases were searched systematically from inception to 01/11/2023. Included were publications examining exposure to placental malperfusion detected on histopathological examination and clinically measured neurodevelopmental outcomes. Publications on multi-pregnancies or animals, exposure to malformations, surgical or medical interventions, review and opinion articles, or those not translated to English, were excluded. Grey literature search and forward and backward citation chaining were performed. The Joanna Briggs Institute's checklists were used for quality assessment. Three studies were pooled using percentages of adjusted associations. Results Nine observational studies fulfilled the eligibility criteria. The included neurodevelopmental outcomes were assessed from 5 days to 8 years when age of assessment is reported. Four publications showed an association between exposure to MVM and poor neurodevelopment at 10 40 months and 8 years, however, no association was observed when examining preterm infants up to 24 months. Conversely, in the six studies examining exposure to FVM, FVM association with neurodevelopmental disorders was reported in two studies looking at preterm infants assessed at 24 months and 8 years and better neurodevelopmental scores in other two studies at 10 40 months. Conclusions The pattern of association between MVM and FVM with neurodevelopmental outcomes varied among the included studies. Clinical and methodological heterogeneities and poor reporting of relevant populations' characteristics hindered full understanding of the results. Methodologically rigorous research is required to help utilise histopathological findings of placental malperfusion in predicting offspring's neurodevelopmental outcomes. En ligne : https://doi.org/10.1111/jcpp.14152 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568