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Auteur Tony CHARMAN |
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Adaptive behavior in autism: Minimal clinically important differences on the Vineland?II / Christopher H. CHATHAM in Autism Research, 11-2 (February 2018)
[article]
Titre : Adaptive behavior in autism: Minimal clinically important differences on the Vineland?II Type de document : Texte imprimé et/ou numérique Auteurs : Christopher H. CHATHAM, Auteur ; K. I. TAYLOR, Auteur ; Tony CHARMAN, Auteur ; X. Liogier D'ARDHUY, Auteur ; E. EULE, Auteur ; A. FEDELE, Auteur ; A. Y. HARDAN, Auteur ; E. LOTH, Auteur ; L. MURTAGH, Auteur ; M. del Valle RUBIDO, Auteur ; Antonia SAN JOSE CACERES, Auteur ; J. SEVIGNY, Auteur ; L. SIKICH, Auteur ; L. SNYDER, Auteur ; J. E. TILLMANN, Auteur ; Pamela VENTOLA, Auteur ; Karen WALTON-BOWEN, Auteur ; P. P. WANG, Auteur ; T. WILLGOSS, Auteur ; Federico BOLOGNANI, Auteur Année de publication : 2018 Article en page(s) : p.270-283 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autism Spectrum Disorder (ASD) is associated with persistent impairments in adaptive abilities across multiple domains. These social, personal, and communicative impairments become increasingly pronounced with development, and are present regardless of IQ. The Vineland Adaptive Behavior Scales, Second Edition (Vineland?II) is the most commonly used instrument for quantifying these impairments, but minimal clinically important differences (MCIDs) on Vineland?II scores have not been rigorously established in ASD. We pooled data from several consortia/registries (EU?AIMS LEAP study, ABIDE?I, ABIDE?II, INFOR, Simons Simplex Collection and Autism Treatment Network [ATN]) and clinical investigations and trials (Stanford, Yale, Roche) resulting in a data set of over 9,000 individuals with ASD. Two approaches were used to estimate MCIDs: distribution?based methods and anchor?based methods. Distribution?based MCID [d?MCID] estimates included the standard error of the measurement, as well as one?fifth and one?half of the covariate?adjusted standard deviation (both cross?sectionally and longitudinally). Anchor?based MCID [a?MCID] estimates include the slope of linear regression of clinician ratings of severity on the Vineland?II score, the slope of linear regression of clinician ratings of longitudinal improvement category on Vineland?II change, the Vineland?II change score maximally differentiating clinical impressions of minimal versus no improvement, and equipercentile equating. Across strata, the Vineland?II Adaptive Behavior Composite standardized score MCID estimates range from 2.01 to 3.2 for distribution?based methods, and from 2.42 to 3.75 for sample?size?weighted anchor?based methods. Lower Vineland?II standardized score MCID estimates were observed for younger and more cognitively impaired populations. These MCID estimates enable users of Vineland?II to assess both the statistical and clinical significance of any observed change. Autism Res 2018, 11: 270–283. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. Lay Summary The Vineland Adaptive Behavior Scales (2nd edition; Vineland?II) is the most widely used scale for assessing day?to?day “adaptive” skills. Yet, it is unknown how much Vineland?II scores must change for those changes to be regarded as clinically significant. We pooled data from over 9,000 individuals with ASD to show that changes of 2–3.75 points on the Vineland?II Composite score represent the “minimal clinically?important difference.” These estimates will help evaluate the benefits of potential new treatments for ASD. En ligne : https://doi.org/10.1002/aur.1874 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=334
in Autism Research > 11-2 (February 2018) . - p.270-283[article] Adaptive behavior in autism: Minimal clinically important differences on the Vineland?II [Texte imprimé et/ou numérique] / Christopher H. CHATHAM, Auteur ; K. I. TAYLOR, Auteur ; Tony CHARMAN, Auteur ; X. Liogier D'ARDHUY, Auteur ; E. EULE, Auteur ; A. FEDELE, Auteur ; A. Y. HARDAN, Auteur ; E. LOTH, Auteur ; L. MURTAGH, Auteur ; M. del Valle RUBIDO, Auteur ; Antonia SAN JOSE CACERES, Auteur ; J. SEVIGNY, Auteur ; L. SIKICH, Auteur ; L. SNYDER, Auteur ; J. E. TILLMANN, Auteur ; Pamela VENTOLA, Auteur ; Karen WALTON-BOWEN, Auteur ; P. P. WANG, Auteur ; T. WILLGOSS, Auteur ; Federico BOLOGNANI, Auteur . - 2018 . - p.270-283.
Langues : Anglais (eng)
in Autism Research > 11-2 (February 2018) . - p.270-283
Index. décimale : PER Périodiques Résumé : Autism Spectrum Disorder (ASD) is associated with persistent impairments in adaptive abilities across multiple domains. These social, personal, and communicative impairments become increasingly pronounced with development, and are present regardless of IQ. The Vineland Adaptive Behavior Scales, Second Edition (Vineland?II) is the most commonly used instrument for quantifying these impairments, but minimal clinically important differences (MCIDs) on Vineland?II scores have not been rigorously established in ASD. We pooled data from several consortia/registries (EU?AIMS LEAP study, ABIDE?I, ABIDE?II, INFOR, Simons Simplex Collection and Autism Treatment Network [ATN]) and clinical investigations and trials (Stanford, Yale, Roche) resulting in a data set of over 9,000 individuals with ASD. Two approaches were used to estimate MCIDs: distribution?based methods and anchor?based methods. Distribution?based MCID [d?MCID] estimates included the standard error of the measurement, as well as one?fifth and one?half of the covariate?adjusted standard deviation (both cross?sectionally and longitudinally). Anchor?based MCID [a?MCID] estimates include the slope of linear regression of clinician ratings of severity on the Vineland?II score, the slope of linear regression of clinician ratings of longitudinal improvement category on Vineland?II change, the Vineland?II change score maximally differentiating clinical impressions of minimal versus no improvement, and equipercentile equating. Across strata, the Vineland?II Adaptive Behavior Composite standardized score MCID estimates range from 2.01 to 3.2 for distribution?based methods, and from 2.42 to 3.75 for sample?size?weighted anchor?based methods. Lower Vineland?II standardized score MCID estimates were observed for younger and more cognitively impaired populations. These MCID estimates enable users of Vineland?II to assess both the statistical and clinical significance of any observed change. Autism Res 2018, 11: 270–283. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. Lay Summary The Vineland Adaptive Behavior Scales (2nd edition; Vineland?II) is the most widely used scale for assessing day?to?day “adaptive” skills. Yet, it is unknown how much Vineland?II scores must change for those changes to be regarded as clinically significant. We pooled data from over 9,000 individuals with ASD to show that changes of 2–3.75 points on the Vineland?II Composite score represent the “minimal clinically?important difference.” These estimates will help evaluate the benefits of potential new treatments for ASD. En ligne : https://doi.org/10.1002/aur.1874 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=334 Adaptive Behaviour and Cognitive Skills: Stability and Change from 7 Months to 7 Years in Siblings at High Familial Risk of Autism Spectrum Disorder / E. SALOMONE in Journal of Autism and Developmental Disorders, 48-9 (September 2018)
[article]
Titre : Adaptive Behaviour and Cognitive Skills: Stability and Change from 7 Months to 7 Years in Siblings at High Familial Risk of Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : E. SALOMONE, Auteur ; E. SHEPHARD, Auteur ; B. MILOSAVLJEVIC, Auteur ; M. H. JOHNSON, Auteur ; Tony CHARMAN, Auteur Article en page(s) : p.2901-2911 Langues : Anglais (eng) Mots-clés : Adaptive behaviour Cognitive ability High familial risk Prospective study Index. décimale : PER Périodiques Résumé : Cognitive and adaptive behaviour abilities early in life provide important clinical prognostic information. We examined stability of such skills in children at high familial risk for ASD who either met diagnostic criteria for ASD at age 7 years (HR-ASD, n = 15) or did not (HR-non-ASD, n = 24) and low-risk control children (LR, n = 37), prospectively studied from infancy. For both HR groups, cognitive skills were consistently lower across time than those of LR children. HR-ASD children showed increasing difficulties in adaptive behaviour over time compared to LR children, while the HR-non-ASD children showed no such difficulties. This pattern of change may inform our understanding of developmental profiles of HR siblings beyond core ASD symptoms. En ligne : http://dx.doi.org/10.1007/s10803-018-3554-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=367
in Journal of Autism and Developmental Disorders > 48-9 (September 2018) . - p.2901-2911[article] Adaptive Behaviour and Cognitive Skills: Stability and Change from 7 Months to 7 Years in Siblings at High Familial Risk of Autism Spectrum Disorder [Texte imprimé et/ou numérique] / E. SALOMONE, Auteur ; E. SHEPHARD, Auteur ; B. MILOSAVLJEVIC, Auteur ; M. H. JOHNSON, Auteur ; Tony CHARMAN, Auteur . - p.2901-2911.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 48-9 (September 2018) . - p.2901-2911
Mots-clés : Adaptive behaviour Cognitive ability High familial risk Prospective study Index. décimale : PER Périodiques Résumé : Cognitive and adaptive behaviour abilities early in life provide important clinical prognostic information. We examined stability of such skills in children at high familial risk for ASD who either met diagnostic criteria for ASD at age 7 years (HR-ASD, n = 15) or did not (HR-non-ASD, n = 24) and low-risk control children (LR, n = 37), prospectively studied from infancy. For both HR groups, cognitive skills were consistently lower across time than those of LR children. HR-ASD children showed increasing difficulties in adaptive behaviour over time compared to LR children, while the HR-non-ASD children showed no such difficulties. This pattern of change may inform our understanding of developmental profiles of HR siblings beyond core ASD symptoms. En ligne : http://dx.doi.org/10.1007/s10803-018-3554-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=367 Alexithymia in Adolescents with Autism Spectrum Disorder: Its Relationship to Internalising Difficulties, Sensory Modulation and Social Cognition / Bosiljka MILOSAVLJEVIC in Journal of Autism and Developmental Disorders, 46-4 (April 2016)
[article]
Titre : Alexithymia in Adolescents with Autism Spectrum Disorder: Its Relationship to Internalising Difficulties, Sensory Modulation and Social Cognition Type de document : Texte imprimé et/ou numérique Auteurs : Bosiljka MILOSAVLJEVIC, Auteur ; Virginia CARTER LENO, Auteur ; Emily SIMONOFF, Auteur ; Gillian BAIRD, Auteur ; Andrew PICKLES, Auteur ; Catherine R. G. JONES, Auteur ; Catherine ERSKINE, Auteur ; Tony CHARMAN, Auteur ; Francesca HAPPE, Auteur Article en page(s) : p.1354-1367 Langues : Anglais (eng) Mots-clés : Alexithymia Autism spectrum disorder Emotion recognition Theory of mind Anxiety Sensory processing Index. décimale : PER Périodiques Résumé : Alexithymia is a personality trait frequently found in adults with autism spectrum disorder (ASD), and has been linked to impairments in emotion recognition and empathy. The presentation of alexithymia within ASD at younger ages remains unexplored, and was examined in the present study. Alexithymia rates were significantly elevated in ASD (55 %; 31/56 scoring above cut-off) versus non-ASD adolescents (16 %; 5/32 scoring above cut-off). Within individuals with ASD, alexithymia was associated with increased self-reported anxiety, parent-reported emotional difficulties, self-reported sensory processing atypicalities, and poorer emotion recognition, but was not associated with theory of mind ability. Overall, our results suggest that alexithymia is highly prevalent, and has selective cognitive correlates in young people with ASD. En ligne : http://dx.doi.org/10.1007/s10803-015-2670-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=284
in Journal of Autism and Developmental Disorders > 46-4 (April 2016) . - p.1354-1367[article] Alexithymia in Adolescents with Autism Spectrum Disorder: Its Relationship to Internalising Difficulties, Sensory Modulation and Social Cognition [Texte imprimé et/ou numérique] / Bosiljka MILOSAVLJEVIC, Auteur ; Virginia CARTER LENO, Auteur ; Emily SIMONOFF, Auteur ; Gillian BAIRD, Auteur ; Andrew PICKLES, Auteur ; Catherine R. G. JONES, Auteur ; Catherine ERSKINE, Auteur ; Tony CHARMAN, Auteur ; Francesca HAPPE, Auteur . - p.1354-1367.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 46-4 (April 2016) . - p.1354-1367
Mots-clés : Alexithymia Autism spectrum disorder Emotion recognition Theory of mind Anxiety Sensory processing Index. décimale : PER Périodiques Résumé : Alexithymia is a personality trait frequently found in adults with autism spectrum disorder (ASD), and has been linked to impairments in emotion recognition and empathy. The presentation of alexithymia within ASD at younger ages remains unexplored, and was examined in the present study. Alexithymia rates were significantly elevated in ASD (55 %; 31/56 scoring above cut-off) versus non-ASD adolescents (16 %; 5/32 scoring above cut-off). Within individuals with ASD, alexithymia was associated with increased self-reported anxiety, parent-reported emotional difficulties, self-reported sensory processing atypicalities, and poorer emotion recognition, but was not associated with theory of mind ability. Overall, our results suggest that alexithymia is highly prevalent, and has selective cognitive correlates in young people with ASD. En ligne : http://dx.doi.org/10.1007/s10803-015-2670-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=284 Alterations in electrophysiological indices of perceptual processing and discrimination are associated with co-occurring emotional and behavioural problems in adolescents with autism spectrum disorder / Virginia CARTER LENO in Molecular Autism, 9 (2018)
[article]
Titre : Alterations in electrophysiological indices of perceptual processing and discrimination are associated with co-occurring emotional and behavioural problems in adolescents with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Virginia CARTER LENO, Auteur ; S. CHANDLER, Auteur ; P. WHITE, Auteur ; I. YORKE, Auteur ; Tony CHARMAN, Auteur ; A. PICKLES, Auteur ; E. SIMONOFF, Auteur Article en page(s) : 50p. Langues : Anglais (eng) Mots-clés : asd Comorbidity eeg erp IAMHealth Perceptual processing Psychopathology Sensory approved by Camden and King's Cross Ethics Sub-Committee (14/LO/2098).Not applicable.AP receives royalties from the Social Communication Questionnaire. The other authors declare that they have no competing interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Index. décimale : PER Périodiques Résumé : Background: Many young people with autism spectrum disorder (ASD) experience emotional and behavioural problems. However, the causes of these co-occurring difficulties are not well understood. Perceptual processing atypicalities are also often reported in individuals with ASD, but how these relate to co-occurring emotional and behavioural problems remains unclear, and few studies have used objective measurement of perceptual processing. Methods: Event-related potentials (ERPs) were recorded in response to both standard and deviant stimuli (which varied in pitch) in an auditory oddball paradigm in adolescents (mean age of 13.56 years, SD = 1.12, range = 11.40-15.70) with ASD (n = 43) with a wide range of IQ (mean IQ of 84.14, SD = 24.24, range 27-129). Response to deviant as compared to standard stimuli (as indexed by the mismatch negativity (MMN)) and response to repeated presentations of standard stimuli (habituation) were measured. Multivariate regression tested the association between neural indices of perceptual processing and co-occurring emotional and behavioural problems. Results: Greater sensitivity to changes in pitch in incoming auditory information (discrimination), as indexed by increased MMN amplitude, was associated with higher levels of parent-rated behaviour problems. MMN amplitude also showed a trend positive correlation with parent-rated sensory hyper-sensitivity. Conversely, greater habituation at the later N2 component was associated with higher levels of emotional problems. Upon more detailed analyses, this appeared to be driven by a selectively greater ERP response to the first (but not the second or third) standard stimuli that followed deviant stimuli. A similar pattern of association was found with other measures of anxiety. All results remained in covariation analyses controlling for age, sex and IQ, although the association between MMN amplitude and behaviour problems became non-significant when controlling for ASD severity. Conclusions: Findings suggest that alterations in mechanisms of perceptual processing and discrimination may be important for understanding co-occurring emotional and behavioural problems in young people with ASD. En ligne : https://dx.doi.org/10.1186/s13229-018-0236-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=371
in Molecular Autism > 9 (2018) . - 50p.[article] Alterations in electrophysiological indices of perceptual processing and discrimination are associated with co-occurring emotional and behavioural problems in adolescents with autism spectrum disorder [Texte imprimé et/ou numérique] / Virginia CARTER LENO, Auteur ; S. CHANDLER, Auteur ; P. WHITE, Auteur ; I. YORKE, Auteur ; Tony CHARMAN, Auteur ; A. PICKLES, Auteur ; E. SIMONOFF, Auteur . - 50p.
Langues : Anglais (eng)
in Molecular Autism > 9 (2018) . - 50p.
Mots-clés : asd Comorbidity eeg erp IAMHealth Perceptual processing Psychopathology Sensory approved by Camden and King's Cross Ethics Sub-Committee (14/LO/2098).Not applicable.AP receives royalties from the Social Communication Questionnaire. The other authors declare that they have no competing interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Index. décimale : PER Périodiques Résumé : Background: Many young people with autism spectrum disorder (ASD) experience emotional and behavioural problems. However, the causes of these co-occurring difficulties are not well understood. Perceptual processing atypicalities are also often reported in individuals with ASD, but how these relate to co-occurring emotional and behavioural problems remains unclear, and few studies have used objective measurement of perceptual processing. Methods: Event-related potentials (ERPs) were recorded in response to both standard and deviant stimuli (which varied in pitch) in an auditory oddball paradigm in adolescents (mean age of 13.56 years, SD = 1.12, range = 11.40-15.70) with ASD (n = 43) with a wide range of IQ (mean IQ of 84.14, SD = 24.24, range 27-129). Response to deviant as compared to standard stimuli (as indexed by the mismatch negativity (MMN)) and response to repeated presentations of standard stimuli (habituation) were measured. Multivariate regression tested the association between neural indices of perceptual processing and co-occurring emotional and behavioural problems. Results: Greater sensitivity to changes in pitch in incoming auditory information (discrimination), as indexed by increased MMN amplitude, was associated with higher levels of parent-rated behaviour problems. MMN amplitude also showed a trend positive correlation with parent-rated sensory hyper-sensitivity. Conversely, greater habituation at the later N2 component was associated with higher levels of emotional problems. Upon more detailed analyses, this appeared to be driven by a selectively greater ERP response to the first (but not the second or third) standard stimuli that followed deviant stimuli. A similar pattern of association was found with other measures of anxiety. All results remained in covariation analyses controlling for age, sex and IQ, although the association between MMN amplitude and behaviour problems became non-significant when controlling for ASD severity. Conclusions: Findings suggest that alterations in mechanisms of perceptual processing and discrimination may be important for understanding co-occurring emotional and behavioural problems in young people with ASD. En ligne : https://dx.doi.org/10.1186/s13229-018-0236-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=371 Altered theta-beta ratio in infancy associates with family history of ADHD and later ADHD-relevant temperamental traits / Jannath BEGUM-ALI in Journal of Child Psychology and Psychiatry, 63-9 (September 2022)
[article]
Titre : Altered theta-beta ratio in infancy associates with family history of ADHD and later ADHD-relevant temperamental traits Type de document : Texte imprimé et/ou numérique Auteurs : Jannath BEGUM-ALI, Auteur ; Amy GOODWIN, Auteur ; Luke MASON, Auteur ; Greg PASCO, Auteur ; Tony CHARMAN, Auteur ; Mark H. JOHNSON, Auteur ; Emily J. H. JONES, Auteur Article en page(s) : p.1057-1067 Langues : Anglais (eng) Mots-clés : Adult Attention Deficit Disorder with Hyperactivity/diagnosis Autism Spectrum Disorder Child Electroencephalography Female Humans Infant Male Prospective Studies Theta Rhythm Attention deficit hyperactivity disorder autism spectrum disorder infancy theta-beta ratio Index. décimale : PER Périodiques Résumé : BACKGROUND: Uncovering the neural mechanisms that underlie symptoms of attention deficit hyperactivity disorder (ADHD) requires studying brain development prior to the emergence of behavioural difficulties. One new approach to this is prospective studies of infants with an elevated likelihood of developing ADHD. METHODS: We used a prospective design to examine an oscillatory electroencephalography profile that has been widely studied in both children and adults with ADHD - the balance between lower and higher frequencies operationalised as the theta-beta ratio (TBR). In the present study, we examined TBR in 136 10-month-old infants (72 male and 64 female) with/without an elevated likelihood of developing ADHD and/or a comparison disorder (Autism Spectrum Disorder; ASD). RESULTS: Infants with a first-degree relative with ADHD demonstrated lower TBR than infants without a first-degree relative with ADHD. Further, lower TBR at 10months was positively associated with temperament dimensions conceptually related to ADHD at 2years. TBR was not altered in infants with a family history of ASD. CONCLUSIONS: This is the first demonstration that alterations in TBR are present prior to behavioural symptoms of ADHD. However, these alterations manifest differently than those sometimes observed in older children with an ADHD diagnosis. Importantly, altered TBR was not seen in infants at elevated likelihood of developing ASD, suggesting a degree of specificity to ADHD. Taken together, these findings demonstrate that there are brain changes associated with a family history of ADHD observable in the first year of life. En ligne : http://dx.doi.org/10.1111/jcpp.13563 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486
in Journal of Child Psychology and Psychiatry > 63-9 (September 2022) . - p.1057-1067[article] Altered theta-beta ratio in infancy associates with family history of ADHD and later ADHD-relevant temperamental traits [Texte imprimé et/ou numérique] / Jannath BEGUM-ALI, Auteur ; Amy GOODWIN, Auteur ; Luke MASON, Auteur ; Greg PASCO, Auteur ; Tony CHARMAN, Auteur ; Mark H. JOHNSON, Auteur ; Emily J. H. JONES, Auteur . - p.1057-1067.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 63-9 (September 2022) . - p.1057-1067
Mots-clés : Adult Attention Deficit Disorder with Hyperactivity/diagnosis Autism Spectrum Disorder Child Electroencephalography Female Humans Infant Male Prospective Studies Theta Rhythm Attention deficit hyperactivity disorder autism spectrum disorder infancy theta-beta ratio Index. décimale : PER Périodiques Résumé : BACKGROUND: Uncovering the neural mechanisms that underlie symptoms of attention deficit hyperactivity disorder (ADHD) requires studying brain development prior to the emergence of behavioural difficulties. One new approach to this is prospective studies of infants with an elevated likelihood of developing ADHD. METHODS: We used a prospective design to examine an oscillatory electroencephalography profile that has been widely studied in both children and adults with ADHD - the balance between lower and higher frequencies operationalised as the theta-beta ratio (TBR). In the present study, we examined TBR in 136 10-month-old infants (72 male and 64 female) with/without an elevated likelihood of developing ADHD and/or a comparison disorder (Autism Spectrum Disorder; ASD). RESULTS: Infants with a first-degree relative with ADHD demonstrated lower TBR than infants without a first-degree relative with ADHD. Further, lower TBR at 10months was positively associated with temperament dimensions conceptually related to ADHD at 2years. TBR was not altered in infants with a family history of ASD. CONCLUSIONS: This is the first demonstration that alterations in TBR are present prior to behavioural symptoms of ADHD. However, these alterations manifest differently than those sometimes observed in older children with an ADHD diagnosis. Importantly, altered TBR was not seen in infants at elevated likelihood of developing ASD, suggesting a degree of specificity to ADHD. Taken together, these findings demonstrate that there are brain changes associated with a family history of ADHD observable in the first year of life. En ligne : http://dx.doi.org/10.1111/jcpp.13563 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 Annual Research Review: Anterior Modifiers in the Emergence of Neurodevelopmental Disorders (AMEND)-a systems neuroscience approach to common developmental disorders / Mark H. JOHNSON in Journal of Child Psychology and Psychiatry, 62-5 (May 2021)
PermalinkAnnual Research Review: Infant development, autism, and ADHD – early pathways to emerging disorders / Mark H. JOHNSON in Journal of Child Psychology and Psychiatry, 56-3 (March 2015)
PermalinkAnxiety and Attentional Bias to Threat in Children at Increased Familial Risk for Autism Spectrum Disorder / B. MILOSAVLJEVIC in Journal of Autism and Developmental Disorders, 47-12 (December 2017)
PermalinkAre child autism symptoms, developmental level and adaptive function associated with caregiver feelings of wellbeing and efficacy in the parenting role? / Lauren J. TAYLOR in Research in Autism Spectrum Disorders, 83 (May 2021)
PermalinkAssociations between early language, motor abilities, and later autism traits in infants with typical and elevated likelihood of autism / Greg PASCO ; Jannath Begum ALI ; Mark H. JOHNSON ; Emily J. H. JONES ; Tony CHARMAN in Autism Research, 16-11 (November 2023)
PermalinkAssociations between theory of mind and conduct problems in autistic and nonautistic youth / Virginia CARTER LENO in Autism Research, 14-2 (February 2021)
PermalinkAt What Age Can ASC Be Detected? / Tony CHARMAN
PermalinkAttitudes of the autism community to early autism research / Sue FLETCHER-WATSON in Autism, 21-1 (January 2017)
PermalinkAtypical Development of Attentional Control Associates with Later Adaptive Functioning, Autism and ADHD Traits / Alexandra HENDRY in Journal of Autism and Developmental Disorders, 50-11 (November 2020)
PermalinkAutism Diagnostic Interview-Revised (ADI-R) Algorithms for Toddlers and Young Preschoolers: Application in a Non-US Sample of 1,104 Children / Annelies A. DE BILDT in Journal of Autism and Developmental Disorders, 45-7 (July 2015)
PermalinkAutism Resources and Information on the Internet or World Wide Web / Tony CHARMAN in Autism, 3-1 (March 1999)
PermalinkAutism Spectrum Disorders at 20 and 42 Months of Age: Stability of Clinical and ADI-R Diagnosis / Antony COX in Journal of Child Psychology and Psychiatry, 40-5 (July 1999)
PermalinkAutistic symptomatology and language ability in autism spectrum disorder and specific language impairment / Tom LOUCAS in Journal of Child Psychology and Psychiatry, 49-11 (November 2008)
PermalinkBeyond intervention into daily life: A systematic review of generalisation following social communication interventions for young children with autism / Sophie CARRUTHERS in Autism Research, 13-4 (April 2020)
PermalinkPermalinkPermalinkPermalinkBrief Report: Associations Between Cognitive Control Processes and Traits of Autism Spectrum Disorder (ASD), attention-Deficit/Hyperactivity Disorder (ADHD) and Anxiety in Children at Elevated and Typical Familial Likelihood for ASD / P. B. G. GODOY in Journal of Autism and Developmental Disorders, 51-8 (August 2021)
PermalinkBrief Report: Associations Between Preverbal Social Communication Skills, Language and Symptom Severity in Children with Autism: An Investigation Using the Early Sociocognitive Battery / Lauren J. TAYLOR in Journal of Autism and Developmental Disorders, 50-4 (April 2020)
PermalinkBrief Report: Coherent Motion Processing in Autism: Is Dot Lifetime an Important Parameter? / Catherine MANNING in Journal of Autism and Developmental Disorders, 45-7 (July 2015)
PermalinkBrief Report: DSM-5 Sensory Behaviours in Children With and Without an Autism Spectrum Disorder / Dido GREEN in Journal of Autism and Developmental Disorders, 46-11 (November 2016)
PermalinkCallous-unemotional traits in youth with autism spectrum disorder (ASD): replication of prevalence estimates and associations with gaze patterns when viewing fearful faces / Virginia CARTER LENO in Development and Psychopathology, 33-4 (October 2021)
PermalinkChild and parent outcomes following parent interventions for child emotional and behavioral problems in autism spectrum disorders: A systematic review and meta-analysis / J. TARVER in Autism, 23-7 (October 2019)
PermalinkCommentary – bridging the research and practice gap in autism: The importance of creating research partnerships with schools / Sarah PARSONS in Autism, 17-3 (May 2013)
PermalinkCommentary: Glass half full or half empty? Testing social communication interventions for young children with autism – reflections on Landa, Holman, O’Neill, and Stuart (2011) / Tony CHARMAN in Journal of Child Psychology and Psychiatry, 52-1 (January 2011)
PermalinkCommentary: Not just genes – reclaiming a role for environmental influences on aetiology and outcome in autism. A commentary on Mandy and Lai (2016) / Tony CHARMAN in Journal of Child Psychology and Psychiatry, 57-3 (March 2016)
PermalinkCommentary: sex difference differences? A reply to Constantino / D. S. MESSINGER in Molecular Autism, 7 (2016)
PermalinkComparing service use and costs among adolescents with autism spectrum disorders, special needs and typical development / Barbara BARRETT in Autism, 19-5 (July 2015)
PermalinkComparison of Parent Questionnaires, Examiner-Led Assessment and Parents' Concerns at 14 Months of Age as Indicators of Later Diagnosis of Autism / Greg PASCO in Journal of Autism and Developmental Disorders, 51-3 (March 2021)
PermalinkConsiderations from the 2017 IMFAR Preconference on Measuring Meaningful Outcomes from School-Age to Adulthood / Vanessa H. BAL in Autism Research, 11-11 (November 2018)
PermalinkCorrection to: The Association Between Emotional and Behavioral Problems in Children with Autism Spectrum Disorder and Psychological Distress in Their Parents: A Systematic Review and Meta-analysis / I. YORKE in Journal of Autism and Developmental Disorders, 48-10 (October 2018)
PermalinkCross-cultural similarities and differences in reporting autistic symptoms in toddlers: A study synthesizing M-CHAT(-R) data from ten countries / Dejan STEVANOVIC in Research in Autism Spectrum Disorders, 95 (July 2022)
PermalinkDépistage des troubles du spectre autistique : les leçons de la recherche et de la pratique clinique / Tony CHARMAN in Enfance, 2009-1 (janvier-mars 2009)
PermalinkDevelopment and Autism: Messages From Developmental Psychopathology / Jacob A. BURACK
PermalinkDevelopment from Preschool through School Age / Tony CHARMAN
PermalinkDevelopment of the Observation Schedule for Children with Autism-Anxiety, Behaviour and Parenting (OSCA-ABP): A New Measure of Child and Parenting Behavior for Use with Young Autistic Children / Melanie PALMER in Journal of Autism and Developmental Disorders, 51-1 (January 2021)
PermalinkDevelopment of the pupillary light reflex from 9 to 24 months: association with common autism spectrum disorder (ASD) genetic liability and 3-year ASD diagnosis / L. A. FISH in Journal of Child Psychology and Psychiatry, 62-11 (November 2021)
PermalinkDevelopmental change in look durations predicts later effortful control in toddlers at familial risk for ASD / A. HENDRY in Journal of Neurodevelopmental Disorders, 10-1 (December 2018)
PermalinkDevelopmental Paths to Anxiety in an Autism-Enriched Infant Cohort: The Role of Temperamental Reactivity and Regulation / M. ERSOY in Journal of Autism and Developmental Disorders, 51-8 (August 2021)
PermalinkDiagnostic stability in young children at risk for autism spectrum disorder: a baby siblings research consortium study / Sally OZONOFF in Journal of Child Psychology and Psychiatry, 56-9 (September 2015)
PermalinkDissecting the phenotypic heterogeneity in sensory features in autism spectrum disorder: a factor mixture modelling approach / J. TILLMANN in Molecular Autism, 11 (2020)
PermalinkEarly development of infants with neurofibromatosis type 1: a case series / A. M. KOLESNIK in Molecular Autism, 8 (2017)
PermalinkEarly developmental pathways to childhood symptoms of attention-deficit hyperactivity disorder, anxiety and autism spectrum disorder / E. SHEPHARD in Journal of Child Psychology and Psychiatry, 60-9 (September 2019)
PermalinkEarly Language Profiles in Infants at High-Risk for Autism Spectrum Disorders / Kristelle HUDRY in Journal of Autism and Developmental Disorders, 44-1 (January 2014)
PermalinkEarly Motor Differences in Infants at Elevated Likelihood of Autism Spectrum Disorder and/or Attention Deficit Hyperactivity Disorder / Jannath BEGUM ALI in Journal of Autism and Developmental Disorders, 50-12 (December 2020)
PermalinkEarly predictors of language skills at 3?years of age vary based on diagnostic outcome: A baby siblings research consortium study / Meredith PECUKONIS in Autism Research, 15-7 (July 2022)
PermalinkEarly sex differences are not autism-specific: A Baby Siblings Research Consortium (BSRC) study / Daniel S. MESSINGER in Molecular Autism, (June 2015)
PermalinkPermalinkEditorial: Envisioning the Future after 50 Years of Science and Discovery / Tony CHARMAN in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)
PermalinkEditorial: Neurobiological models of childhood depression and parenting models of childhood anxiety / Tony CHARMAN in Journal of Child Psychology and Psychiatry, 49-12 (December 2008)
PermalinkEditorial: Prevention in the community and treatment in the clinic – two different methodological approaches to determining the evidence-base for child mental health interventions / Tony CHARMAN in Journal of Child Psychology and Psychiatry, 49-5 (May 2008)
PermalinkEditorial: The value of longitudinal studies for understanding continuity and variability in development / Tony CHARMAN in Journal of Child Psychology and Psychiatry, 50-12 (December 2009)
PermalinkEditorial: Why a diversity of methods are required to understand childhood disorders / Tony CHARMAN in Journal of Child Psychology and Psychiatry, 48-11 (November 2007)
PermalinkEEG hyper-connectivity in high-risk infants is associated with later autism / Elena V. OREKHOVA in Journal of Neurodevelopmental Disorders, 6-1 (December 2014)
PermalinkElephants in Pyjamas: Testing the Weak Central Coherence Account of Autism Spectrum Disorders Using a Syntactic Disambiguation Task / N. G. RICHES in Journal of Autism and Developmental Disorders, 46-1 (January 2016)
PermalinkEmotional and behavioural problems in children and young people with autism spectrum disorder in specialist autism schools / Erica SALOMONE in Research in Autism Spectrum Disorders, 8-6 (June 2014)
PermalinkErratum to: Sex differences in the association between infant markers and later autistic traits / Rachael BEDFORD in Molecular Autism, 7 (2016)
PermalinkEthical dimensions of translational developmental neuroscience research in autism / A. MANZINI in Journal of Child Psychology and Psychiatry, 62-11 (November 2021)
PermalinkL'étude britannique sur les nourrissons frères et soeurs d'enfants avec autisme (BASIS, British Autism Study of Infant Siblings) / Tony CHARMAN in Bulletin Scientifique de l'arapi (Le), 34 (Décembre 2014)
PermalinkEvaluating Sex and Age Differences in ADI-R and ADOS Scores in a Large European Multi-site Sample of Individuals with Autism Spectrum Disorder / J. TILLMANN in Journal of Autism and Developmental Disorders, 48-7 (July 2018)
PermalinkEveryday Memory’ Impairments in Autism Spectrum Disorders / Catherine R. G. JONES in Journal of Autism and Developmental Disorders, 41-4 (April 2011)
PermalinkL'évolution du développement social, communicatif et des comportements ritualisés dans l'autisme infantile. Etude diagnostique clinique comparative et évaluation à l'aide de l'ADI-R à 20 mois et à 42 mois / Tony CHARMAN in Bulletin Scientifique de l'arapi (Le), 1 (juin 1998)
PermalinkExamining the relationship between cognitive inflexibility and internalizing and externalizing symptoms in autistic children and adolescents: A systematic review and meta-analysis / Jiedi LEI in Autism Research, 15-12 (December 2022)
PermalinkExploring the neurocognitive correlates of challenging behaviours in young people with autism spectrum disorder / Virginia CARTER LENO in Autism, 23-5 (July 2019)
PermalinkFacial expression recognition is linked to clinical and neurofunctional differences in autism / Hannah MEYER-LINDENBERG in Molecular Autism, 13 (2022)
PermalinkFactors associated with mental health symptoms among UK autistic children and young people and their parents during the COVID-19 pandemic / Melanie PALMER in Autism, 27-7 (October 2023)
PermalinkFamilial risk of autism alters subcortical and cerebellar brain anatomy in infants and predicts the emergence of repetitive behaviors in early childhood / I. POTE in Autism Research, 12-4 (April 2019)
PermalinkFeasibility study of the National Autistic Society EarlyBird parent support programme / M. PALMER in Autism, 24-1 (January 2020)
PermalinkGaps in Current Autism Research: The Thoughts of the Autism Research Editorial Board and Associate Editors / David G. AMARAL in Autism Research, 12-5 (May 2019)
PermalinkGray matter covariations and core symptoms of autism: the EU-AIMS Longitudinal European Autism Project / Ting MEI in Molecular Autism, 11 (2020)
PermalinkPermalinkHealth-related quality of life in children with autism spectrum disorders and children with developmental language disorders / Catherine COALES in Autism & Developmental Language Impairments, 4 (January-December 2019)
PermalinkHealth-related quality of life in children with autism spectrum disorders and children with developmental language disorders / Catherine COALES in Autism & Developmental Language Impairments, 4 (January-December 2019)
PermalinkHeart rate mean and variability as a biomarker for phenotypic variation in preschoolers with autism spectrum disorder / T. BAZELMANS in Autism Research, 12-1 (January 2019)
PermalinkHow do autistic people fare in adult life and can we predict it from childhood? / Rachel KENT ; Tony CHARMAN ; Gillian BAIRD ; Andrew PICKLES ; Emily SIMONOFF in Autism Research, 16-2 (February 2023)
PermalinkHow do core autism traits and associated symptoms relate to quality of life? Findings from the Longitudinal European Autism Project / Bethany OAKLEY in Autism, 25-2 (February 2021)
PermalinkImitation and the Development of Language / Tony CHARMAN
PermalinkInfant excitation/inhibition balance interacts with executive attention to predict autistic traits in childhood / Virginia CARTER LENO in Molecular Autism, 13 (2022)
PermalinkInfant Neural Sensitivity to Dynamic Eye Gaze Relates to Quality of Parent–Infant Interaction at 7-Months in Infants at Risk for Autism / Mayada ELSABBAGH in Journal of Autism and Developmental Disorders, 45-2 (February 2015)
PermalinkInfant regulatory function acts as a protective factor for later traits of autism spectrum disorder and attention deficit/hyperactivity disorder but not callous unemotional traits / Rachael BEDFORD in Journal of Neurodevelopmental Disorders, 11-1 (December 2019)
PermalinkInfant sleep predicts trajectories of social attention and later autism traits / Jannath BEGUM-ALI in Journal of Child Psychology and Psychiatry, 64-8 (August 2023)
PermalinkIntervention for Infants at Risk of Developing Autism: A Case Series / Jonathan GREEN in Journal of Autism and Developmental Disorders, 43-11 (November 2013)
PermalinkIntervention Services for Autistic Adults: An ASDEU Study of Autistic Adults, Carers, and Professionals' Experiences / Martina MICAI in Journal of Autism and Developmental Disorders, 52-4 (April 2022)
PermalinkIntroducing 'Predictive Parenting': A Feasibility Study of a New Group Parenting Intervention Targeting Emotional and Behavioral Difficulties in Children with Autism Spectrum Disorder / Victoria HALLETT in Journal of Autism and Developmental Disorders, 51-1 (January 2021)
PermalinkInvestigating the cross-cultural validity of DSM-5 autism spectrum disorder: Evidence from Finnish and UK samples / William MANDY in Autism, 18-1 (January 2014)
PermalinkInvestigating the factors underlying adaptive functioning in autism in the EU-AIMS Longitudinal European Autism Project / J. TILLMANN in Autism Research, 12-4 (April 2019)
PermalinkLanguage growth in children with heterogeneous language disorders: a population study / Courtenay F. NORBURY in Journal of Child Psychology and Psychiatry, 58-10 (October 2017)
PermalinkLatent trajectories of adaptive behaviour in infants at high and low familial risk for autism spectrum disorder / G. BUSSU in Molecular Autism, 10 (2019)
PermalinkLateral glances toward moving stimuli among young children with autism: Early regulation of locally oriented perception? / Laurent MOTTRON in Development and Psychopathology, 19-1 (Winter 2007)
PermalinkLinking functional and structural brain organisation with behaviour in autism: a multimodal EU-AIMS Longitudinal European Autism Project (LEAP) study / Alberto LLERA ; Ting MEI ; Koen HAAK ; Christina ISAKOGLOU ; Dorothea L. FLORIS ; Sarah DURSTON ; Carolin MOESSNANG ; Tobias BANASCHEWSKI ; Simon BARON-COHEN ; Eva LOTH ; Flavio DELL'ACQUA ; Tony CHARMAN ; Declan G. M. MURPHY ; Christine ECKER ; Jan K. BUITELAAR ; Christian F. BECKMANN in Molecular Autism, 14 (2023)
PermalinkLook duration at the face as a developmental endophenotype: elucidating pathways to autism and ADHD / Anna GUI in Development and Psychopathology, 32-4 (October 2020)
PermalinkLoss of language in early development of autism and specific language impairment / Andrew PICKLES in Journal of Child Psychology and Psychiatry, 50-7 (July 2009)
PermalinkMaking the future together: Shaping autism research through meaningful participation / Sue FLETCHER-WATSON in Autism, 23-4 (May 2019)
PermalinkMeasurement of urine indolylacroylglycine is not useful in the diagnosis or dietary management of autism / Neil R. DALTON in Autism Research, 10-3 (March 2017)
PermalinkMediation of 6-year mid-childhood follow-up outcomes after pre-school social communication (PACT) therapy for autistic children: randomised controlled trial / Andrew PICKLES ; Tony CHARMAN ; Helen MCCONACHIE ; Ann LE COUTEUR ; Vicky SLONIMS ; Patricia HOWLIN ; Rachel COLLUM ; Erica SALOMONE ; Hannah TOBIN ; Isobel GAMMER ; Jessica MAXWELL ; Catherine ALDRED ; Jeremy PARR ; Kathy LEADBITTER ; Jonathan GREEN in Journal of Child Psychology and Psychiatry, 65-2 (February 2024)
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