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Centre Hospitalier le Vinatier
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15-10 - October 2022 [Texte imprimé et/ou numérique] . - 2022. Langues : Anglais (eng)
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Exemplaires (1)
Code-barres | Cote | Support | Localisation | Section | Disponibilité |
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PER0002025 | PER ARE | Périodique | Centre d'Information et de Documentation du CRA Rhône-Alpes | PER - Périodiques | Exclu du prêt |
Dépouillements


[article]
Titre : Autism 101 Commentaries Type de document : Texte imprimé et/ou numérique Article en page(s) : p.1786 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.2807 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=487
in Autism Research > 15-10 (October 2022) . - p.1786[article] Autism 101 Commentaries [Texte imprimé et/ou numérique] . - p.1786.
Langues : Anglais (eng)
in Autism Research > 15-10 (October 2022) . - p.1786
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.2807 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=487 What does it mean for an autism intervention to be evidence-based? / Giacomo VIVANTI in Autism Research, 15-10 (October 2022)
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[article]
Titre : What does it mean for an autism intervention to be evidence-based? Type de document : Texte imprimé et/ou numérique Auteurs : Giacomo VIVANTI, Auteur Article en page(s) : p.1787-1793 Langues : Anglais (eng) Mots-clés : autism behavioral intervention early intervention evidence-based practices intervention neurodiversity social skills intervention Index. décimale : PER Périodiques Résumé : Although there is consensus in the field that individuals on the autism spectrum should receive interventions that are evidence-based, the concept of "evidence-based" is multifaceted and subject to ongoing development and debate. In this commentary, we review historical developments, methodological approaches, as well as areas of controversies and research directions in the establishment of an evidence base for autism intervention. LAY SUMMARY: What does it mean for an autism intervention to be evidence-based? In this commentary, we address this complex issue by examining historical developments, methodological approaches, as well as areas of ongoing debate in the establishment of evidence-based interventions for autism. En ligne : http://dx.doi.org/10.1002/aur.2792 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism Research > 15-10 (October 2022) . - p.1787-1793[article] What does it mean for an autism intervention to be evidence-based? [Texte imprimé et/ou numérique] / Giacomo VIVANTI, Auteur . - p.1787-1793.
Langues : Anglais (eng)
in Autism Research > 15-10 (October 2022) . - p.1787-1793
Mots-clés : autism behavioral intervention early intervention evidence-based practices intervention neurodiversity social skills intervention Index. décimale : PER Périodiques Résumé : Although there is consensus in the field that individuals on the autism spectrum should receive interventions that are evidence-based, the concept of "evidence-based" is multifaceted and subject to ongoing development and debate. In this commentary, we review historical developments, methodological approaches, as well as areas of controversies and research directions in the establishment of an evidence base for autism intervention. LAY SUMMARY: What does it mean for an autism intervention to be evidence-based? In this commentary, we address this complex issue by examining historical developments, methodological approaches, as well as areas of ongoing debate in the establishment of evidence-based interventions for autism. En ligne : http://dx.doi.org/10.1002/aur.2792 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 Motor abilities as a possible specifier of autism: A response to Bhat (2021) / Alessandro CRIPPA in Autism Research, 15-10 (October 2022)
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[article]
Titre : Motor abilities as a possible specifier of autism: A response to Bhat (2021) Type de document : Texte imprimé et/ou numérique Auteurs : Alessandro CRIPPA, Auteur Article en page(s) : p.1794-1795 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.2805 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism Research > 15-10 (October 2022) . - p.1794-1795[article] Motor abilities as a possible specifier of autism: A response to Bhat (2021) [Texte imprimé et/ou numérique] / Alessandro CRIPPA, Auteur . - p.1794-1795.
Langues : Anglais (eng)
in Autism Research > 15-10 (October 2022) . - p.1794-1795
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.2805 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 Supporting the need for the motor domain to be included in the definition of autism spectrum disorder: A response to Bishop et al.'s critique of Bhat (2021) / Leah R. KETCHESON in Autism Research, 15-10 (October 2022)
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[article]
Titre : Supporting the need for the motor domain to be included in the definition of autism spectrum disorder: A response to Bishop et al.'s critique of Bhat (2021) Type de document : Texte imprimé et/ou numérique Auteurs : Leah R. KETCHESON, Auteur ; E. Andrew PITCHFORD, Auteur ; Kerri L. STAPLES, Auteur ; Megan MACDONALD, Auteur ; Dale A. ULRICH, Auteur Article en page(s) : p.1796-1798 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.2811 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism Research > 15-10 (October 2022) . - p.1796-1798[article] Supporting the need for the motor domain to be included in the definition of autism spectrum disorder: A response to Bishop et al.'s critique of Bhat (2021) [Texte imprimé et/ou numérique] / Leah R. KETCHESON, Auteur ; E. Andrew PITCHFORD, Auteur ; Kerri L. STAPLES, Auteur ; Megan MACDONALD, Auteur ; Dale A. ULRICH, Auteur . - p.1796-1798.
Langues : Anglais (eng)
in Autism Research > 15-10 (October 2022) . - p.1796-1798
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.2811 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 Revisiting the simplification of adult language input in the context of naturalistic developmental behavioral interventions: A commentary / Kyle M. FROST in Autism Research, 15-10 (October 2022)
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[article]
Titre : Revisiting the simplification of adult language input in the context of naturalistic developmental behavioral interventions: A commentary Type de document : Texte imprimé et/ou numérique Auteurs : Kyle M. FROST, Auteur ; Brooke R. INGERSOLL, Auteur ; Courtney E. VENKER, Auteur Article en page(s) : p.1799-1809 Langues : Anglais (eng) Mots-clés : autism spectrum disorder children communication early intervention language modeling naturalistic developmental behavioral interventions Index. décimale : PER Périodiques Résumé : Naturalistic developmental behavioral interventions (NDBI) are an evidence-based class of early interventions for improving language and social communication skills in autistic children. However, relatively little is known about how individual elements of NDBI support child development. This commentary focuses on one common element across NDBI models: the simplification of adult language input. Advances in developmental science focusing on the length and complexity of adult spoken utterances suggests that natural, grammatical utterances facilitate comprehension and expressive language development in autistic and nonautistic children. Yet, NDBI tend to recommend shorter and simpler adult utterances. We close by describing directions for future research which would inform recommendations around adult language input in NDBI to optimally support child language and communication development. En ligne : http://dx.doi.org/10.1002/aur.2796 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism Research > 15-10 (October 2022) . - p.1799-1809[article] Revisiting the simplification of adult language input in the context of naturalistic developmental behavioral interventions: A commentary [Texte imprimé et/ou numérique] / Kyle M. FROST, Auteur ; Brooke R. INGERSOLL, Auteur ; Courtney E. VENKER, Auteur . - p.1799-1809.
Langues : Anglais (eng)
in Autism Research > 15-10 (October 2022) . - p.1799-1809
Mots-clés : autism spectrum disorder children communication early intervention language modeling naturalistic developmental behavioral interventions Index. décimale : PER Périodiques Résumé : Naturalistic developmental behavioral interventions (NDBI) are an evidence-based class of early interventions for improving language and social communication skills in autistic children. However, relatively little is known about how individual elements of NDBI support child development. This commentary focuses on one common element across NDBI models: the simplification of adult language input. Advances in developmental science focusing on the length and complexity of adult spoken utterances suggests that natural, grammatical utterances facilitate comprehension and expressive language development in autistic and nonautistic children. Yet, NDBI tend to recommend shorter and simpler adult utterances. We close by describing directions for future research which would inform recommendations around adult language input in NDBI to optimally support child language and communication development. En ligne : http://dx.doi.org/10.1002/aur.2796 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 Effects of age on the hippocampus and verbal memory in adults with autism spectrum disorder: Longitudinal versus cross-sectional findings / Broc A. PAGNI in Autism Research, 15-10 (October 2022)
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[article]
Titre : Effects of age on the hippocampus and verbal memory in adults with autism spectrum disorder: Longitudinal versus cross-sectional findings Type de document : Texte imprimé et/ou numérique Auteurs : Broc A. PAGNI, Auteur ; Melissa J. M. WALSH, Auteur ; Edward OFORI, Auteur ; Kewei CHEN, Auteur ; Georgia SULLIVAN, Auteur ; Jocelyn ALVAR, Auteur ; Leanna MONAHAN, Auteur ; Nicolas GUERITHAULT, Auteur ; Shanna DELANEY, Auteur ; B. Blair BRADEN, Auteur Article en page(s) : p.1810-1823 Langues : Anglais (eng) Mots-clés : aging/ASD in adults executive functioning hippocampus longitudinal data analysis magnetic resonance imaging - structural memory neuroimaging Index. décimale : PER Périodiques Résumé : Research studying aging in adults with autism spectrum disorder (ASD) is growing, but longitudinal work is needed. Autistic adults have increased risk of dementia, altered hippocampal volumes and fornix integrity, and verbal memory difficulties compared with neurotypical (NT) adults. This study examined longitudinal aging in middle-age adults with ASD versus a matched NT group, and compared findings with cross-sectional age effects across a broad adult age range. Participants were 194 adults with (n = 106; 74 male) and without (n = 88; 52 male) ASD, ages 18-71. Participants (n = 45; 40-70 age range) with two visits (2-3 years apart) were included in a longitudinal analysis. Hippocampal volume, fornix fractional anisotropy (FA), and verbal memory were measured via T1-weighted MRI, diffusion tensor imaging, and the Rey Auditory Verbal Learning Test, respectively. Longitudinal mixed models were used for hippocampal system variables and reliable change index categories were used for Auditory Verbal Learning Test analyses. Multivariate regression was used for cross-sectional analyses. Middle-age adults with ASD had greater longitudinal hippocampal volume loss and were more likely to show clinically meaningful decline in short-term memory, compared with NT. In contrast, cross-sectional associations between increasing age and worsening short-term memory were identified in NT, but not autistic adults. Reduced fornix FA and long-term memory in ASD were found across the broad cross-sectional age range. These preliminary longitudinal findings suggest accelerated hippocampal volume loss in ASD and slightly higher rates of clinically-meaningful decline in verbal short-term memory. Contradictory cross-sectional and longitudinal results underscore the importance of longitudinal aging research in autistic adults. LAY SUMMARY: Autistic adults have increased risk of dementia, differences in brain memory structures, and difficulty with memory compared with neurotypical (NT) adults. However, there are no publications that follow the same middle-age autistic adults over time to see how their brain and memory change. Our preliminary findings in a small middle-age autism sample suggest a key memory brain structure, the hippocampus, may shrink faster over 2-3 years compared with NT, and short-term memory may become more challenging for some. Across a broad adult range, autistic adults also had reduced integrity of connections to the hippocampus and greater challenges with long-term memory. In our larger sample across a broad age range, the results did not hint at this aforementioned pattern of accelerated aging. This underscores the importance of more aging research in autism, and especially research where people are followed over time. En ligne : http://dx.doi.org/10.1002/aur.2797 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism Research > 15-10 (October 2022) . - p.1810-1823[article] Effects of age on the hippocampus and verbal memory in adults with autism spectrum disorder: Longitudinal versus cross-sectional findings [Texte imprimé et/ou numérique] / Broc A. PAGNI, Auteur ; Melissa J. M. WALSH, Auteur ; Edward OFORI, Auteur ; Kewei CHEN, Auteur ; Georgia SULLIVAN, Auteur ; Jocelyn ALVAR, Auteur ; Leanna MONAHAN, Auteur ; Nicolas GUERITHAULT, Auteur ; Shanna DELANEY, Auteur ; B. Blair BRADEN, Auteur . - p.1810-1823.
Langues : Anglais (eng)
in Autism Research > 15-10 (October 2022) . - p.1810-1823
Mots-clés : aging/ASD in adults executive functioning hippocampus longitudinal data analysis magnetic resonance imaging - structural memory neuroimaging Index. décimale : PER Périodiques Résumé : Research studying aging in adults with autism spectrum disorder (ASD) is growing, but longitudinal work is needed. Autistic adults have increased risk of dementia, altered hippocampal volumes and fornix integrity, and verbal memory difficulties compared with neurotypical (NT) adults. This study examined longitudinal aging in middle-age adults with ASD versus a matched NT group, and compared findings with cross-sectional age effects across a broad adult age range. Participants were 194 adults with (n = 106; 74 male) and without (n = 88; 52 male) ASD, ages 18-71. Participants (n = 45; 40-70 age range) with two visits (2-3 years apart) were included in a longitudinal analysis. Hippocampal volume, fornix fractional anisotropy (FA), and verbal memory were measured via T1-weighted MRI, diffusion tensor imaging, and the Rey Auditory Verbal Learning Test, respectively. Longitudinal mixed models were used for hippocampal system variables and reliable change index categories were used for Auditory Verbal Learning Test analyses. Multivariate regression was used for cross-sectional analyses. Middle-age adults with ASD had greater longitudinal hippocampal volume loss and were more likely to show clinically meaningful decline in short-term memory, compared with NT. In contrast, cross-sectional associations between increasing age and worsening short-term memory were identified in NT, but not autistic adults. Reduced fornix FA and long-term memory in ASD were found across the broad cross-sectional age range. These preliminary longitudinal findings suggest accelerated hippocampal volume loss in ASD and slightly higher rates of clinically-meaningful decline in verbal short-term memory. Contradictory cross-sectional and longitudinal results underscore the importance of longitudinal aging research in autistic adults. LAY SUMMARY: Autistic adults have increased risk of dementia, differences in brain memory structures, and difficulty with memory compared with neurotypical (NT) adults. However, there are no publications that follow the same middle-age autistic adults over time to see how their brain and memory change. Our preliminary findings in a small middle-age autism sample suggest a key memory brain structure, the hippocampus, may shrink faster over 2-3 years compared with NT, and short-term memory may become more challenging for some. Across a broad adult range, autistic adults also had reduced integrity of connections to the hippocampus and greater challenges with long-term memory. In our larger sample across a broad age range, the results did not hint at this aforementioned pattern of accelerated aging. This underscores the importance of more aging research in autism, and especially research where people are followed over time. En ligne : http://dx.doi.org/10.1002/aur.2797 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 Dietary intake in children on the autism spectrum is altered and linked to differences in autistic traits and sensory processing styles / Nisha E. MATHEW in Autism Research, 15-10 (October 2022)
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[article]
Titre : Dietary intake in children on the autism spectrum is altered and linked to differences in autistic traits and sensory processing styles Type de document : Texte imprimé et/ou numérique Auteurs : Nisha E. MATHEW, Auteur ; Kylie-Ann MALLITT, Auteur ; Anne MASI, Auteur ; Tamarah KATZ, Auteur ; Adam K. WALKER, Auteur ; Margaret J. MORRIS, Auteur ; Chee Y. OOI, Auteur Article en page(s) : p.1824-1839 Langues : Anglais (eng) Mots-clés : adolescents autism children diet intake diet quality eating sensory processing Index. décimale : PER Périodiques Résumé : Diets of children and adolescents on the autism spectrum often differ when compared to their non-autistic peers. Most dietary studies have been limited by small sample sizes and rarely assess the heterogeneity of autism. Addressing this gap, this study compared the anthropometrics, dietary composition, dietary quality, and food variety of 154 Australian children and adolescents on the spectrum and 213 non-autistic children (71 siblings and 142 unrelated controls). Beyond the case-control approach, within-group comparisons assessed the influence of autism clinical presentations and sensory processing styles on body mass index (BMI) and measures of dietary intake among those on the spectrum. In this word first study of diet that included between-group comparisons with non-autistic peers (siblings and an unrelated comparison group) and within-autism group comparisons, we found that children on the spectrum consumed limited variety and lower quality of food and non-autistic siblings also ate comparably higher levels of energy-dense, nutrient poor food, and less diary. This may be due to autistic traits influencing family's diets or shared sensory sensitivities driving dietary intake. Within the autism group, higher autistic traits were associated with lower BMIs and a specific dietary pattern higher in simple carbohydrates and lower in unprocessed protein. Contrastingly, greater sensitivity to sensory stimuli was associated with a healthier diet. Increased age was linked to more varied diets but also diets higher in saturated fats and energy-dense, nutrient poor foods. Overall, this research highlights that potential mediators of dietary intake, such as familial influences, autistic traits, sensory processing styles, age and sex, need to be considered when assessing diet in the autistic population. LAY SUMMARY: In this study of dietary differences linked to autism, children, and teenagers on the spectrum ate fewer different foods and were less likely to eat recommended amounts of fruits and vegetables when compared to non-autistic siblings and unrelated children and teenagers. There were also family differences, in that those on the spectrum and their siblings ate more unhealthy foods and less dairy. Among those on the spectrum, dietary differences were linked to age, sex, autistic traits and sensory processing styles. En ligne : http://dx.doi.org/10.1002/aur.2798 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism Research > 15-10 (October 2022) . - p.1824-1839[article] Dietary intake in children on the autism spectrum is altered and linked to differences in autistic traits and sensory processing styles [Texte imprimé et/ou numérique] / Nisha E. MATHEW, Auteur ; Kylie-Ann MALLITT, Auteur ; Anne MASI, Auteur ; Tamarah KATZ, Auteur ; Adam K. WALKER, Auteur ; Margaret J. MORRIS, Auteur ; Chee Y. OOI, Auteur . - p.1824-1839.
Langues : Anglais (eng)
in Autism Research > 15-10 (October 2022) . - p.1824-1839
Mots-clés : adolescents autism children diet intake diet quality eating sensory processing Index. décimale : PER Périodiques Résumé : Diets of children and adolescents on the autism spectrum often differ when compared to their non-autistic peers. Most dietary studies have been limited by small sample sizes and rarely assess the heterogeneity of autism. Addressing this gap, this study compared the anthropometrics, dietary composition, dietary quality, and food variety of 154 Australian children and adolescents on the spectrum and 213 non-autistic children (71 siblings and 142 unrelated controls). Beyond the case-control approach, within-group comparisons assessed the influence of autism clinical presentations and sensory processing styles on body mass index (BMI) and measures of dietary intake among those on the spectrum. In this word first study of diet that included between-group comparisons with non-autistic peers (siblings and an unrelated comparison group) and within-autism group comparisons, we found that children on the spectrum consumed limited variety and lower quality of food and non-autistic siblings also ate comparably higher levels of energy-dense, nutrient poor food, and less diary. This may be due to autistic traits influencing family's diets or shared sensory sensitivities driving dietary intake. Within the autism group, higher autistic traits were associated with lower BMIs and a specific dietary pattern higher in simple carbohydrates and lower in unprocessed protein. Contrastingly, greater sensitivity to sensory stimuli was associated with a healthier diet. Increased age was linked to more varied diets but also diets higher in saturated fats and energy-dense, nutrient poor foods. Overall, this research highlights that potential mediators of dietary intake, such as familial influences, autistic traits, sensory processing styles, age and sex, need to be considered when assessing diet in the autistic population. LAY SUMMARY: In this study of dietary differences linked to autism, children, and teenagers on the spectrum ate fewer different foods and were less likely to eat recommended amounts of fruits and vegetables when compared to non-autistic siblings and unrelated children and teenagers. There were also family differences, in that those on the spectrum and their siblings ate more unhealthy foods and less dairy. Among those on the spectrum, dietary differences were linked to age, sex, autistic traits and sensory processing styles. En ligne : http://dx.doi.org/10.1002/aur.2798 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 Patterns of sensory modulation by age and sex in young people on the autism spectrum / Alison E. LANE in Autism Research, 15-10 (October 2022)
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[article]
Titre : Patterns of sensory modulation by age and sex in young people on the autism spectrum Type de document : Texte imprimé et/ou numérique Auteurs : Alison E. LANE, Auteur ; Kate SIMPSON, Auteur ; Anne MASI, Auteur ; Rachel GROVE, Auteur ; Mohammad Ali MONI, Auteur ; Alicia MONTGOMERY, Auteur ; Jacqui ROBERTS, Auteur ; Natalie SILOVE, Auteur ; Olivia WHALEN, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; Valsamma EAPEN, Auteur Article en page(s) : p.1840-1854 Langues : Anglais (eng) Mots-clés : age autism spectrum cluster analysis sensory sensory modulation sex subtypes young people Index. décimale : PER Périodiques Résumé : Sensory modulation symptoms form a diagnostic criterion for autism spectrum disorder and are associated with significant daily functional limitations. Utilizing caregiver report on Short Sensory Profile-2 (SSP-2) for 919 autistic children (3-14.11 years), we examined the expression of sensory modulation symptoms by age and sex and investigated the existence of specific sensory modulation subtypes. Sensory modulation symptoms appeared to peak in frequency during middle childhood, particularly in sensory sensitivity and avoidance. Symptoms associated with sensory hypo-reactivity and seeking tended not differ between age cohorts. Males and females demonstrated similar overall sensory modulation profiles, however, females showed elevated symptoms relating to sensory sensitivity. Model-based cluster analysis revealed five interpretable sensory modulation subtypes which related to symptom severity (low, mid-range, high). Subtypes demonstrating mid-range symptom severity differed in focus on sensory hyper-reactivity or seeking symptoms. The findings of this study report for the first time that age-related differences in sensory modulation symptoms may be associated with sensory hyper-reactivity only. The subtyping results also suggest that sensory modulation symptom severity is a reliable means of classifying variance within autistic children, however, consideration of differences in the behavioral strategies employed by individuals to manage sensory modulation symptoms may inform tailored supportive strategies. LAY SUMMARY: We studied sensory symptoms such as over-responding, under-responding and sensation seeking behaviors in 919 autistic children and adolescents. We found that 6-12-year-olds and females displayed the most sensory over-responding symptoms. Autistic children could be grouped into mild, moderate, and severe levels of sensory symptoms, however, children differed in the type of strategies used to cope with their sensory symptoms meaning that they may require different intervention approaches. En ligne : http://dx.doi.org/10.1002/aur.2762 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism Research > 15-10 (October 2022) . - p.1840-1854[article] Patterns of sensory modulation by age and sex in young people on the autism spectrum [Texte imprimé et/ou numérique] / Alison E. LANE, Auteur ; Kate SIMPSON, Auteur ; Anne MASI, Auteur ; Rachel GROVE, Auteur ; Mohammad Ali MONI, Auteur ; Alicia MONTGOMERY, Auteur ; Jacqui ROBERTS, Auteur ; Natalie SILOVE, Auteur ; Olivia WHALEN, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; Valsamma EAPEN, Auteur . - p.1840-1854.
Langues : Anglais (eng)
in Autism Research > 15-10 (October 2022) . - p.1840-1854
Mots-clés : age autism spectrum cluster analysis sensory sensory modulation sex subtypes young people Index. décimale : PER Périodiques Résumé : Sensory modulation symptoms form a diagnostic criterion for autism spectrum disorder and are associated with significant daily functional limitations. Utilizing caregiver report on Short Sensory Profile-2 (SSP-2) for 919 autistic children (3-14.11 years), we examined the expression of sensory modulation symptoms by age and sex and investigated the existence of specific sensory modulation subtypes. Sensory modulation symptoms appeared to peak in frequency during middle childhood, particularly in sensory sensitivity and avoidance. Symptoms associated with sensory hypo-reactivity and seeking tended not differ between age cohorts. Males and females demonstrated similar overall sensory modulation profiles, however, females showed elevated symptoms relating to sensory sensitivity. Model-based cluster analysis revealed five interpretable sensory modulation subtypes which related to symptom severity (low, mid-range, high). Subtypes demonstrating mid-range symptom severity differed in focus on sensory hyper-reactivity or seeking symptoms. The findings of this study report for the first time that age-related differences in sensory modulation symptoms may be associated with sensory hyper-reactivity only. The subtyping results also suggest that sensory modulation symptom severity is a reliable means of classifying variance within autistic children, however, consideration of differences in the behavioral strategies employed by individuals to manage sensory modulation symptoms may inform tailored supportive strategies. LAY SUMMARY: We studied sensory symptoms such as over-responding, under-responding and sensation seeking behaviors in 919 autistic children and adolescents. We found that 6-12-year-olds and females displayed the most sensory over-responding symptoms. Autistic children could be grouped into mild, moderate, and severe levels of sensory symptoms, however, children differed in the type of strategies used to cope with their sensory symptoms meaning that they may require different intervention approaches. En ligne : http://dx.doi.org/10.1002/aur.2762 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 Mapping the time course of overt emotion dysregulation, self-injurious behavior, and aggression in psychiatrically hospitalized autistic youth: A naturalistic study / Jessie B. NORTHRUP in Autism Research, 15-10 (October 2022)
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[article]
Titre : Mapping the time course of overt emotion dysregulation, self-injurious behavior, and aggression in psychiatrically hospitalized autistic youth: A naturalistic study Type de document : Texte imprimé et/ou numérique Auteurs : Jessie B. NORTHRUP, Auteur ; Matthew S. GOODWIN, Auteur ; Christine B. PEURA, Auteur ; Qi CHEN, Auteur ; Briana J. TAYLOR, Auteur ; Matthew S. SIEGEL, Auteur ; Carla A. MAZEFSKY, Auteur Article en page(s) : p.1855-1867 Langues : Anglais (eng) Mots-clés : aggressive behavior autism inpatient collection autism spectrum disorder emotion dysregulation self-injurious behavior Index. décimale : PER Périodiques Résumé : Challenges with emotion dysregulation, self-injurious behavior (SIB), and aggression are common in autistic individuals. Prior research on the relationships between these behaviors is limited mainly to cross-sectional correlations of parent-report data. Understanding how emotion dysregulation, SIB, and aggression present and relate to one another in real-time could add to our understanding of the context and function of these behaviors. The present study examined the real-time occurrence and temporal relationships between these behaviors in 53 psychiatrically hospitalized autistic youth. Over 500 hours of behavioral observation occurred during everyday activities in the hospital. Start and stop times for instances of overt emotion dysregulation, SIB, and aggression were coded live using a custom mobile phone app. Results indicated large individual variability in the frequency and duration of these behaviors and their co-occurrence. Both SIB and aggression co-occurred with overt emotion dysregulation at above-chance levels, suggesting a role for emotional distress in the occurrence of these behaviors. However, there was substantial variability within and between individuals in co-occurrence, and SIB and aggression often (and for some individuals, almost always) occurred without overt emotion dysregulation. Relatedly, cross-recurrence quantitative analysis revealed that SIB and aggression preceded emotion dysregulation more often than emotion dysregulation preceded SIB and aggression. Future research, perhaps using ambulatory psychophysiological measures, is needed to understand whether emotion dysregulation may sometimes be present but not easily observed during SIB and aggression. LAY SUMMARY: This study provides insight into how overt emotion dysregulation (i.e., visible distress), aggression, and self-injury unfold in real-time for autistic individuals. Participants were 53 autistic youth staying in a psychiatric hospital. Research staff observed participants in everyday activities on the hospital unit and noted instances of aggression, self-injurious behavior, and emotion dysregulation. Results suggest that aggression and self-injury sometimes occur with visible signs of distress but also often occur without visible distress. In addition, observable distress was more common in the moments after these behaviors than in the moments before. En ligne : http://dx.doi.org/10.1002/aur.2773 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism Research > 15-10 (October 2022) . - p.1855-1867[article] Mapping the time course of overt emotion dysregulation, self-injurious behavior, and aggression in psychiatrically hospitalized autistic youth: A naturalistic study [Texte imprimé et/ou numérique] / Jessie B. NORTHRUP, Auteur ; Matthew S. GOODWIN, Auteur ; Christine B. PEURA, Auteur ; Qi CHEN, Auteur ; Briana J. TAYLOR, Auteur ; Matthew S. SIEGEL, Auteur ; Carla A. MAZEFSKY, Auteur . - p.1855-1867.
Langues : Anglais (eng)
in Autism Research > 15-10 (October 2022) . - p.1855-1867
Mots-clés : aggressive behavior autism inpatient collection autism spectrum disorder emotion dysregulation self-injurious behavior Index. décimale : PER Périodiques Résumé : Challenges with emotion dysregulation, self-injurious behavior (SIB), and aggression are common in autistic individuals. Prior research on the relationships between these behaviors is limited mainly to cross-sectional correlations of parent-report data. Understanding how emotion dysregulation, SIB, and aggression present and relate to one another in real-time could add to our understanding of the context and function of these behaviors. The present study examined the real-time occurrence and temporal relationships between these behaviors in 53 psychiatrically hospitalized autistic youth. Over 500 hours of behavioral observation occurred during everyday activities in the hospital. Start and stop times for instances of overt emotion dysregulation, SIB, and aggression were coded live using a custom mobile phone app. Results indicated large individual variability in the frequency and duration of these behaviors and their co-occurrence. Both SIB and aggression co-occurred with overt emotion dysregulation at above-chance levels, suggesting a role for emotional distress in the occurrence of these behaviors. However, there was substantial variability within and between individuals in co-occurrence, and SIB and aggression often (and for some individuals, almost always) occurred without overt emotion dysregulation. Relatedly, cross-recurrence quantitative analysis revealed that SIB and aggression preceded emotion dysregulation more often than emotion dysregulation preceded SIB and aggression. Future research, perhaps using ambulatory psychophysiological measures, is needed to understand whether emotion dysregulation may sometimes be present but not easily observed during SIB and aggression. LAY SUMMARY: This study provides insight into how overt emotion dysregulation (i.e., visible distress), aggression, and self-injury unfold in real-time for autistic individuals. Participants were 53 autistic youth staying in a psychiatric hospital. Research staff observed participants in everyday activities on the hospital unit and noted instances of aggression, self-injurious behavior, and emotion dysregulation. Results suggest that aggression and self-injury sometimes occur with visible signs of distress but also often occur without visible distress. In addition, observable distress was more common in the moments after these behaviors than in the moments before. En ligne : http://dx.doi.org/10.1002/aur.2773 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 Is traditional back translation enough? Comparison of translation methodology for an ASD screening tool / Michaela DUBAY in Autism Research, 15-10 (October 2022)
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[article]
Titre : Is traditional back translation enough? Comparison of translation methodology for an ASD screening tool Type de document : Texte imprimé et/ou numérique Auteurs : Michaela DUBAY, Auteur ; John SIDERIS, Auteur ; Erica ROUCH, Auteur Article en page(s) : p.1868-1882 Langues : Anglais (eng) Mots-clés : autism spectrum disorder culture hispanic or latino language parents psychometrics surveys and questionnaires Index. décimale : PER Périodiques Résumé : Early identification of autism spectrum disorders (ASD) in non-English speaking children often relies on translation of English ASD screening measures. Most measures employ a forward-back translation approach, despite data suggesting that this method may result in poor psychometric properties. Some studies in non-ASD fields have suggested that a rigorous method of translation with cultural adaptation may yield better psychometric properties, but no studies in the ASD field have compared the two approaches directly. This investigation compares these two translation methodologies to determine if they produce psychometrically similar or dissimilar measures. Three hundred and eighty US-based Spanish-speaking caregivers of children 8-16 months old were randomly assigned to complete either a forward-back Spanish translation or a rigorous translation with cultural adaptation of a parent-report ASD screening tool. Measurement invariance analyses determined that the two translations were psychometrically dissimilar. Additional qualitative explanatory methods using cognitive interviews examined textual differences and participant preferences between non-invariant items. LAY SUMMARY: Autism screening questionnaires created in English need to be translated into other languages so non-English speaking parents can fill them out accurately. Traditionally, researchers have not considered cultural differences when they translate these questionnaires. When we compared a direct translation to a translation with cultural adaptations, the two questionnaires were statistically different. Parents interpreted and responded to the same questions differently, depending on which version they filled out. En ligne : http://dx.doi.org/10.1002/aur.2783 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism Research > 15-10 (October 2022) . - p.1868-1882[article] Is traditional back translation enough? Comparison of translation methodology for an ASD screening tool [Texte imprimé et/ou numérique] / Michaela DUBAY, Auteur ; John SIDERIS, Auteur ; Erica ROUCH, Auteur . - p.1868-1882.
Langues : Anglais (eng)
in Autism Research > 15-10 (October 2022) . - p.1868-1882
Mots-clés : autism spectrum disorder culture hispanic or latino language parents psychometrics surveys and questionnaires Index. décimale : PER Périodiques Résumé : Early identification of autism spectrum disorders (ASD) in non-English speaking children often relies on translation of English ASD screening measures. Most measures employ a forward-back translation approach, despite data suggesting that this method may result in poor psychometric properties. Some studies in non-ASD fields have suggested that a rigorous method of translation with cultural adaptation may yield better psychometric properties, but no studies in the ASD field have compared the two approaches directly. This investigation compares these two translation methodologies to determine if they produce psychometrically similar or dissimilar measures. Three hundred and eighty US-based Spanish-speaking caregivers of children 8-16 months old were randomly assigned to complete either a forward-back Spanish translation or a rigorous translation with cultural adaptation of a parent-report ASD screening tool. Measurement invariance analyses determined that the two translations were psychometrically dissimilar. Additional qualitative explanatory methods using cognitive interviews examined textual differences and participant preferences between non-invariant items. LAY SUMMARY: Autism screening questionnaires created in English need to be translated into other languages so non-English speaking parents can fill them out accurately. Traditionally, researchers have not considered cultural differences when they translate these questionnaires. When we compared a direct translation to a translation with cultural adaptations, the two questionnaires were statistically different. Parents interpreted and responded to the same questions differently, depending on which version they filled out. En ligne : http://dx.doi.org/10.1002/aur.2783 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 Pathways to adaptive functioning in autism from early childhood to adolescence / Susie CHANDLER in Autism Research, 15-10 (October 2022)
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[article]
Titre : Pathways to adaptive functioning in autism from early childhood to adolescence Type de document : Texte imprimé et/ou numérique Auteurs : Susie CHANDLER, Auteur ; Virginia CARTER LENO, Auteur ; Phillipa WHITE, Auteur ; Isabel YORKE, Auteur ; Matthew J. HOLLOCKS, Auteur ; Gillian BAIRD, Auteur ; Andrew PICKLES, Auteur ; Emily SIMONOFF, Auteur ; Tony CHARMAN, Auteur Article en page(s) : p.1883-1893 Langues : Anglais (eng) Mots-clés : Adhd adaptive function autism behavioral problems emotional problems Index. décimale : PER Périodiques Résumé : Adaptive functioning is lower in many autistic individuals to a greater extent than would be expected based on IQ. However, the clinical features associated with these difficulties are less well understood. This study examines longitudinal and contemporaneous associations of adaptive functioning in autistic youth across a wide ability range. Parent-reported autism symptoms, co-occurring emotional, behavioral and attention deficit hyperactivity disorder (ADHD) symptoms, and IQ were assessed in early childhood (M age 7 years; T1) and 6 years later in adolescence (M age 13 years; T2) in 179 autistic youth. Adaptive functioning was assessed at T2. Structural equation modeling estimated pathways to adaptive functioning from autism, and psychiatric symptoms at T1 and T2, testing whether associations were driven by continuity of behaviors from T1 to T2 or their contemporaneous effect at T2, or both, controlling for T1 IQ. Lower adaptive functioning at T2 was associated with higher T1 and T2 ADHD symptoms (Î2 = -0.14, andÎ2 = -0.21) but not behavioral nor emotional symptoms at either timepoint. Lower adaptive functioning at T2 was also associated with lower T1 IQ (Î2 = 0.43) and higher social communication symptoms (Î2 = -0.37) at T2 but not T1, but the relationship with ADHD symptoms remained. Paths were not moderated by sex or IQ. Increased symptoms of ADHD, both in early childhood and contemporaneously, were associated with reduced adaptive functioning in adolescence. Co-occurring ADHD may be a modifiable risk factor for adaptive function impairments and should be routinely assessed and when present evidence-based treatments initiated which may benefit adaptive functioning outcomes. LAY SUMMARY: Adaptive functioning is lower in many autistic individuals to a greater extent than would be expected based on IQ. However, the clinical features associated with these difficulties are less well understood. In a community sample higher attention deficit/hyperactivity disorder (ADHD) symptoms, but not emotional or behavioral symptoms, in both early childhood and contemporaneously were associated with lower adaptive functioning in autistic adolescents. Co-occurring ADHD may be a modifiable risk factor for adaptive function difficulties in autism. En ligne : http://dx.doi.org/10.1002/aur.2785 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism Research > 15-10 (October 2022) . - p.1883-1893[article] Pathways to adaptive functioning in autism from early childhood to adolescence [Texte imprimé et/ou numérique] / Susie CHANDLER, Auteur ; Virginia CARTER LENO, Auteur ; Phillipa WHITE, Auteur ; Isabel YORKE, Auteur ; Matthew J. HOLLOCKS, Auteur ; Gillian BAIRD, Auteur ; Andrew PICKLES, Auteur ; Emily SIMONOFF, Auteur ; Tony CHARMAN, Auteur . - p.1883-1893.
Langues : Anglais (eng)
in Autism Research > 15-10 (October 2022) . - p.1883-1893
Mots-clés : Adhd adaptive function autism behavioral problems emotional problems Index. décimale : PER Périodiques Résumé : Adaptive functioning is lower in many autistic individuals to a greater extent than would be expected based on IQ. However, the clinical features associated with these difficulties are less well understood. This study examines longitudinal and contemporaneous associations of adaptive functioning in autistic youth across a wide ability range. Parent-reported autism symptoms, co-occurring emotional, behavioral and attention deficit hyperactivity disorder (ADHD) symptoms, and IQ were assessed in early childhood (M age 7 years; T1) and 6 years later in adolescence (M age 13 years; T2) in 179 autistic youth. Adaptive functioning was assessed at T2. Structural equation modeling estimated pathways to adaptive functioning from autism, and psychiatric symptoms at T1 and T2, testing whether associations were driven by continuity of behaviors from T1 to T2 or their contemporaneous effect at T2, or both, controlling for T1 IQ. Lower adaptive functioning at T2 was associated with higher T1 and T2 ADHD symptoms (Î2 = -0.14, andÎ2 = -0.21) but not behavioral nor emotional symptoms at either timepoint. Lower adaptive functioning at T2 was also associated with lower T1 IQ (Î2 = 0.43) and higher social communication symptoms (Î2 = -0.37) at T2 but not T1, but the relationship with ADHD symptoms remained. Paths were not moderated by sex or IQ. Increased symptoms of ADHD, both in early childhood and contemporaneously, were associated with reduced adaptive functioning in adolescence. Co-occurring ADHD may be a modifiable risk factor for adaptive function impairments and should be routinely assessed and when present evidence-based treatments initiated which may benefit adaptive functioning outcomes. LAY SUMMARY: Adaptive functioning is lower in many autistic individuals to a greater extent than would be expected based on IQ. However, the clinical features associated with these difficulties are less well understood. In a community sample higher attention deficit/hyperactivity disorder (ADHD) symptoms, but not emotional or behavioral symptoms, in both early childhood and contemporaneously were associated with lower adaptive functioning in autistic adolescents. Co-occurring ADHD may be a modifiable risk factor for adaptive function difficulties in autism. En ligne : http://dx.doi.org/10.1002/aur.2785 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 Examination of pubertal timing and tempo in females and males with autism spectrum disorder compared to typically developing youth / Blythe A. CORBETT in Autism Research, 15-10 (October 2022)
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[article]
Titre : Examination of pubertal timing and tempo in females and males with autism spectrum disorder compared to typically developing youth Type de document : Texte imprimé et/ou numérique Auteurs : Blythe A. CORBETT, Auteur ; Rachael A. MUSCATELLO, Auteur ; Ahra KIM, Auteur ; Simon VANDEKAR, Auteur ; Sara DUFFUS, Auteur ; Sloane SPARKS, Auteur ; Yasas TANGUTURI, Auteur Article en page(s) : p.1894-1908 Langues : Anglais (eng) Mots-clés : adolescence autism development female puberty Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is characterized by impaired social communication and poor adaptation to change; thus, pubertal development may be precarious. Pubertal timing and tempo were measured in 244 youth (7.9% Black, 83.3% White, and 8.7% multiracial) with ASD (N = 140) and typical development (N = 104). Pubertal development was measured using Tanner staging of Genital (G, males), Breast (B, females), and pubic hair (PH) in both sexes at Year 1 (10-13 years), Year 2 (11-14 years), and Year 3 (12-15 years). Nonlinear mixed effects models analyzed interindividual differences in timing and tempo. For both sexes, ASD and higher body mass index were associated with earlier pubertal timing. Males generally exhibited faster tempo than females. Linear regression models did not show associations between pubertal timing and internalizing symptoms at time three. Findings showing advanced pubertal maturation in ASD youth suggest greater risk of psychological, social, and physiological challenges. LAY SUMMARY: Youth with ASD have difficulty in social communication and adaption to change, thus puberty may be a challenging transition. The study examined onset (timing) and progression (tempo) of puberty over three years, using physical exam, in 244 adolescents with and without ASD, enrolled at ages 10-13. ASD youth started puberty earlier, while males generally progressed at a faster pace. Further examination of puberty in ASD should identify impact on social, behavioral, and mental health outcomes. En ligne : http://dx.doi.org/10.1002/aur.2786 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism Research > 15-10 (October 2022) . - p.1894-1908[article] Examination of pubertal timing and tempo in females and males with autism spectrum disorder compared to typically developing youth [Texte imprimé et/ou numérique] / Blythe A. CORBETT, Auteur ; Rachael A. MUSCATELLO, Auteur ; Ahra KIM, Auteur ; Simon VANDEKAR, Auteur ; Sara DUFFUS, Auteur ; Sloane SPARKS, Auteur ; Yasas TANGUTURI, Auteur . - p.1894-1908.
Langues : Anglais (eng)
in Autism Research > 15-10 (October 2022) . - p.1894-1908
Mots-clés : adolescence autism development female puberty Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is characterized by impaired social communication and poor adaptation to change; thus, pubertal development may be precarious. Pubertal timing and tempo were measured in 244 youth (7.9% Black, 83.3% White, and 8.7% multiracial) with ASD (N = 140) and typical development (N = 104). Pubertal development was measured using Tanner staging of Genital (G, males), Breast (B, females), and pubic hair (PH) in both sexes at Year 1 (10-13 years), Year 2 (11-14 years), and Year 3 (12-15 years). Nonlinear mixed effects models analyzed interindividual differences in timing and tempo. For both sexes, ASD and higher body mass index were associated with earlier pubertal timing. Males generally exhibited faster tempo than females. Linear regression models did not show associations between pubertal timing and internalizing symptoms at time three. Findings showing advanced pubertal maturation in ASD youth suggest greater risk of psychological, social, and physiological challenges. LAY SUMMARY: Youth with ASD have difficulty in social communication and adaption to change, thus puberty may be a challenging transition. The study examined onset (timing) and progression (tempo) of puberty over three years, using physical exam, in 244 adolescents with and without ASD, enrolled at ages 10-13. ASD youth started puberty earlier, while males generally progressed at a faster pace. Further examination of puberty in ASD should identify impact on social, behavioral, and mental health outcomes. En ligne : http://dx.doi.org/10.1002/aur.2786 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 Online administration of the ADOS for research with adolescents and adults in response to the pandemic / Inge-Marie EIGSTI in Autism Research, 15-10 (October 2022)
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[article]
Titre : Online administration of the ADOS for research with adolescents and adults in response to the pandemic Type de document : Texte imprimé et/ou numérique Auteurs : Inge-Marie EIGSTI, Auteur ; Rebecca P. THOMAS, Auteur ; Mackenzie STABILE, Auteur ; Anusha MOHAN, Auteur ; Mary F. S. DIECKHAUS, Auteur ; Jason CRUTCHER, Auteur ; Elise TAVERNA, Auteur ; Deborah A. FEIN, Auteur Article en page(s) : p.1909-1916 Langues : Anglais (eng) Mots-clés : Covid autism diagnosis online videoconference Index. décimale : PER Périodiques Résumé : This study evaluates an online ADOS-2 Module 4 administration. Adolescents and adults with (n = 24; 7 females) and without (n = 13; 5 females) a history of autism spectrum disorder (ASD) completed the ADOS-2 Module 4 via videoconference. Parents or caregivers completed the Parent/Caregiver Form of the Vineland Adaptive Behavior Scales and the Achenbach Adult Behavior Checklist. The ADOS-2 was reviewed and scored by five trained clinicians and supervised by a senior clinician with established research reliability. The autistic group's scores differed on ADOS total (Calibrated Severity Score, WPS instrument) and domain scores, KSADS domain scores, and Achenbach T-scores. Inter-rater reliability was "moderate" (κ = 0.732), and percentage item-wise agreement was r = 0.69. The online ADOS-2 showed significant convergence with parent-reported assessments of ASD-relevant symptoms and characteristics, suggesting it was a valid assessment. While any online assessments must be used with caution, results suggest that the approach described here could have sufficient validity and reliability to fill the urgent need to assess and evaluate ASD symptomatology, as one component of a thorough clinical evaluation of ASD-related behaviors. LAY SUMMARY: In this exploratory study, we asked whether it was possible to give the ADOS-2 to adolescents and adults in a completely online way. Results showed that expert clinicians agreed on 69% of ADOS-2 items; also, participants with autism had higher scores on all parts of the ADOS-2. The online ADOS-2 scores had strong and significant relationships with parents' reports of friendship and social skills. While we need more research that tests this method, this way of doing the ADOS-2 online may be useful for clinicians and researchers who have an urgent need to evaluate autism during the pandemic. En ligne : http://dx.doi.org/10.1002/aur.2791 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism Research > 15-10 (October 2022) . - p.1909-1916[article] Online administration of the ADOS for research with adolescents and adults in response to the pandemic [Texte imprimé et/ou numérique] / Inge-Marie EIGSTI, Auteur ; Rebecca P. THOMAS, Auteur ; Mackenzie STABILE, Auteur ; Anusha MOHAN, Auteur ; Mary F. S. DIECKHAUS, Auteur ; Jason CRUTCHER, Auteur ; Elise TAVERNA, Auteur ; Deborah A. FEIN, Auteur . - p.1909-1916.
Langues : Anglais (eng)
in Autism Research > 15-10 (October 2022) . - p.1909-1916
Mots-clés : Covid autism diagnosis online videoconference Index. décimale : PER Périodiques Résumé : This study evaluates an online ADOS-2 Module 4 administration. Adolescents and adults with (n = 24; 7 females) and without (n = 13; 5 females) a history of autism spectrum disorder (ASD) completed the ADOS-2 Module 4 via videoconference. Parents or caregivers completed the Parent/Caregiver Form of the Vineland Adaptive Behavior Scales and the Achenbach Adult Behavior Checklist. The ADOS-2 was reviewed and scored by five trained clinicians and supervised by a senior clinician with established research reliability. The autistic group's scores differed on ADOS total (Calibrated Severity Score, WPS instrument) and domain scores, KSADS domain scores, and Achenbach T-scores. Inter-rater reliability was "moderate" (κ = 0.732), and percentage item-wise agreement was r = 0.69. The online ADOS-2 showed significant convergence with parent-reported assessments of ASD-relevant symptoms and characteristics, suggesting it was a valid assessment. While any online assessments must be used with caution, results suggest that the approach described here could have sufficient validity and reliability to fill the urgent need to assess and evaluate ASD symptomatology, as one component of a thorough clinical evaluation of ASD-related behaviors. LAY SUMMARY: In this exploratory study, we asked whether it was possible to give the ADOS-2 to adolescents and adults in a completely online way. Results showed that expert clinicians agreed on 69% of ADOS-2 items; also, participants with autism had higher scores on all parts of the ADOS-2. The online ADOS-2 scores had strong and significant relationships with parents' reports of friendship and social skills. While we need more research that tests this method, this way of doing the ADOS-2 online may be useful for clinicians and researchers who have an urgent need to evaluate autism during the pandemic. En ligne : http://dx.doi.org/10.1002/aur.2791 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 Reexamining empathy in autism: Empathic disequilibrium as a novel predictor of autism diagnosis and autistic traits / Ido SHALEV in Autism Research, 15-10 (October 2022)
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[article]
Titre : Reexamining empathy in autism: Empathic disequilibrium as a novel predictor of autism diagnosis and autistic traits Type de document : Texte imprimé et/ou numérique Auteurs : Ido SHALEV, Auteur ; Varun WARRIER, Auteur ; David M. GREENBERG, Auteur ; Paula SMITH, Auteur ; Carrie ALLISON, Auteur ; Simon BARON-COHEN, Auteur ; Alal ERAN, Auteur ; Florina UZEFOVSKY, Auteur Article en page(s) : p.1917-1928 Langues : Anglais (eng) Mots-clés : autism cognitive emotional empathy empathy response surface analysis Index. décimale : PER Périodiques Résumé : A large body of research showed that autistic people have intact emotional (affective) empathy alongside reduced cognitive empathy. However, there are mixed findings and these call for a more subtle understanding of empathy in autism. Empathic disequilibrium refers to the imbalance between emotional and cognitive empathy and is associated with a higher number of autistic traits in the typical population. Here we examined whether empathic disequilibrium predicts both the number of autistic traits and autism diagnosis. In a large sample of autistic (N = 1905) and typical individuals (N = 3009), we examined empathic disequilibrium and empathy as predictors of autistic traits and autism diagnosis, using a polynomial regression with response surface analysis. Empathy and autistic traits were measured using validated self-report questionnaires. Both empathic disequilibrium and empathy predicted linearly and non-linearly autism diagnosis and autistic traits. Specifically, a tendency towards higher emotional than cognitive empathy (empathic disequilibrium towards emotional empathy) predicted both autism diagnosis and the social domain of autistic traits, while higher cognitive than emotional empathy was associated with the non-social domain of autism. Empathic disequilibrium was also more prominent in autistic females. This study provides evidence that beyond empathy as was measured thus far, empathic disequilibrium offers a novel analytical approach for examining the role of empathy. Empathic disequilibrium allows for a more nuanced understanding of the links between empathy and autism. LAY SUMMARY: Many autistic individuals report feelings of excessive empathy, yet their experience is not reflected by most of the current literature, typically suggesting that autism is characterized by intact emotional and reduced cognitive empathy. To fill this gap, we looked at both ends of the imbalance between these components, termed empathic disequilibrium. We show that, like empathy, empathic disequilibrium is related to autism diagnosis and traits, and thus may provide a more nuanced understanding of empathy and its link with autism. En ligne : http://dx.doi.org/10.1002/aur.2794 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism Research > 15-10 (October 2022) . - p.1917-1928[article] Reexamining empathy in autism: Empathic disequilibrium as a novel predictor of autism diagnosis and autistic traits [Texte imprimé et/ou numérique] / Ido SHALEV, Auteur ; Varun WARRIER, Auteur ; David M. GREENBERG, Auteur ; Paula SMITH, Auteur ; Carrie ALLISON, Auteur ; Simon BARON-COHEN, Auteur ; Alal ERAN, Auteur ; Florina UZEFOVSKY, Auteur . - p.1917-1928.
Langues : Anglais (eng)
in Autism Research > 15-10 (October 2022) . - p.1917-1928
Mots-clés : autism cognitive emotional empathy empathy response surface analysis Index. décimale : PER Périodiques Résumé : A large body of research showed that autistic people have intact emotional (affective) empathy alongside reduced cognitive empathy. However, there are mixed findings and these call for a more subtle understanding of empathy in autism. Empathic disequilibrium refers to the imbalance between emotional and cognitive empathy and is associated with a higher number of autistic traits in the typical population. Here we examined whether empathic disequilibrium predicts both the number of autistic traits and autism diagnosis. In a large sample of autistic (N = 1905) and typical individuals (N = 3009), we examined empathic disequilibrium and empathy as predictors of autistic traits and autism diagnosis, using a polynomial regression with response surface analysis. Empathy and autistic traits were measured using validated self-report questionnaires. Both empathic disequilibrium and empathy predicted linearly and non-linearly autism diagnosis and autistic traits. Specifically, a tendency towards higher emotional than cognitive empathy (empathic disequilibrium towards emotional empathy) predicted both autism diagnosis and the social domain of autistic traits, while higher cognitive than emotional empathy was associated with the non-social domain of autism. Empathic disequilibrium was also more prominent in autistic females. This study provides evidence that beyond empathy as was measured thus far, empathic disequilibrium offers a novel analytical approach for examining the role of empathy. Empathic disequilibrium allows for a more nuanced understanding of the links between empathy and autism. LAY SUMMARY: Many autistic individuals report feelings of excessive empathy, yet their experience is not reflected by most of the current literature, typically suggesting that autism is characterized by intact emotional and reduced cognitive empathy. To fill this gap, we looked at both ends of the imbalance between these components, termed empathic disequilibrium. We show that, like empathy, empathic disequilibrium is related to autism diagnosis and traits, and thus may provide a more nuanced understanding of empathy and its link with autism. En ligne : http://dx.doi.org/10.1002/aur.2794 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 Exclusion of females in autism research: Empirical evidence for a "leaky" recruitment-to-research pipeline / Anila M. D'MELLO in Autism Research, 15-10 (October 2022)
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Titre : Exclusion of females in autism research: Empirical evidence for a "leaky" recruitment-to-research pipeline Type de document : Texte imprimé et/ou numérique Auteurs : Anila M. D'MELLO, Auteur ; Isabelle R. FROSCH, Auteur ; Cindy E. LI, Auteur ; Annie L. CARDINAUX, Auteur ; John D. E. GABRIELI, Auteur Article en page(s) : p.1929-1940 Langues : Anglais (eng) Mots-clés : Abide Ados Autism Physical Health Survey Channel 4 Images LifeLines Musicial Universe Spark autism spectrum disorder diagnosis exclusion criteria females inclusion criteria recruitment sex differences Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is characterized by challenges in social communication and the presence of repetitive behaviors or restricted interests. Notably, males are four times as likely as females to be diagnosed with autism. Despite efforts to increase representation and characterization of autistic females, research studies consistently enroll small samples of females, or exclude females altogether. Importantly, researchers often rely on standardized measures to confirm diagnosis prior to enrollment in research studies. We retrospectively analyzed the effects of one such measure (Autism Diagnostic Observation Schedule, ADOS) on research inclusion/exclusion rates by sex in autistic adults, all of whom had a preexisting community diagnosis of autism (n = 145, 95 male, 50 female). Using the ADOS as a confirmatory diagnostic measure resulted in the exclusion of autistic females at a rate over 2.5 times higher than that of autistic males. We compared sex ratios in our sample to those in other large, publically available datasets that rely either on community diagnosis (6 datasets, total n = 42,209) or standardized assessments (2 datasets, total n = 214) to determine eligibility of participants for research. Reliance on community diagnosis rather than confirmatory diagnostic assessments resulted in significantly more equal sex ratios. These results provide evidence for a "leaky" recruitment-to-research pipeline for females in autism research. LAY SUMMARY: Despite efforts to increase the representation of autistic females in research, studies consistently enroll small samples of females or exclude females altogether. We find that despite making up almost 50% of the initially recruited sample based upon self-report of community diagnosis, autistic females are disproportonately excluded from research participation as a result of commonly used autism diagnostic measures. In our sample, and several other publically available datasets, reliance on community diagnosis resulted in significantly more equal sex ratios. En ligne : http://dx.doi.org/10.1002/aur.2795 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism Research > 15-10 (October 2022) . - p.1929-1940[article] Exclusion of females in autism research: Empirical evidence for a "leaky" recruitment-to-research pipeline [Texte imprimé et/ou numérique] / Anila M. D'MELLO, Auteur ; Isabelle R. FROSCH, Auteur ; Cindy E. LI, Auteur ; Annie L. CARDINAUX, Auteur ; John D. E. GABRIELI, Auteur . - p.1929-1940.
Langues : Anglais (eng)
in Autism Research > 15-10 (October 2022) . - p.1929-1940
Mots-clés : Abide Ados Autism Physical Health Survey Channel 4 Images LifeLines Musicial Universe Spark autism spectrum disorder diagnosis exclusion criteria females inclusion criteria recruitment sex differences Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is characterized by challenges in social communication and the presence of repetitive behaviors or restricted interests. Notably, males are four times as likely as females to be diagnosed with autism. Despite efforts to increase representation and characterization of autistic females, research studies consistently enroll small samples of females, or exclude females altogether. Importantly, researchers often rely on standardized measures to confirm diagnosis prior to enrollment in research studies. We retrospectively analyzed the effects of one such measure (Autism Diagnostic Observation Schedule, ADOS) on research inclusion/exclusion rates by sex in autistic adults, all of whom had a preexisting community diagnosis of autism (n = 145, 95 male, 50 female). Using the ADOS as a confirmatory diagnostic measure resulted in the exclusion of autistic females at a rate over 2.5 times higher than that of autistic males. We compared sex ratios in our sample to those in other large, publically available datasets that rely either on community diagnosis (6 datasets, total n = 42,209) or standardized assessments (2 datasets, total n = 214) to determine eligibility of participants for research. Reliance on community diagnosis rather than confirmatory diagnostic assessments resulted in significantly more equal sex ratios. These results provide evidence for a "leaky" recruitment-to-research pipeline for females in autism research. LAY SUMMARY: Despite efforts to increase the representation of autistic females in research, studies consistently enroll small samples of females or exclude females altogether. We find that despite making up almost 50% of the initially recruited sample based upon self-report of community diagnosis, autistic females are disproportonately excluded from research participation as a result of commonly used autism diagnostic measures. In our sample, and several other publically available datasets, reliance on community diagnosis resulted in significantly more equal sex ratios. En ligne : http://dx.doi.org/10.1002/aur.2795 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 Association of urinary polycyclic aromatic hydrocarbon metabolites with symptoms among autistic children: A case-control study in Tianjin, China / Peiying LI in Autism Research, 15-10 (October 2022)
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[article]
Titre : Association of urinary polycyclic aromatic hydrocarbon metabolites with symptoms among autistic children: A case-control study in Tianjin, China Type de document : Texte imprimé et/ou numérique Auteurs : Peiying LI, Auteur ; Qiaoyun YANG, Auteur ; Yao LI, Auteur ; Yu HAN, Auteur ; Zhiyi QU, Auteur ; Lei GAO, Auteur ; Tingkai CUI, Auteur ; Wenjuan XIONG, Auteur ; Wei XI, Auteur ; Xin ZHANG, Auteur Article en page(s) : p.1941-1960 Langues : Anglais (eng) Mots-clés : autism spectrum disorder behavioral characteristics case-control study children internal exposure polycyclic aromatic hydrocarbon Index. décimale : PER Périodiques Résumé : Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous pollutants that are associated with altered neurodevelopment and various neurodevelopmental disorders. However, studies evaluating internal biomarkers of PAH exposure in reference to the severity of autism spectrum disorder (ASD) symptomology and autistic behaviors are scarce. Hence, we conducted a case-control study evaluating 12 urinary hydroxylated PAH metabolites (i.e., hydroxy-PAHs) in 101 children with autism and 101 neurotypical children, matching according to sex and age in a 1:1 ratio. In children with ASD, the severity of symptomology and autistic behaviors were assessed using the child autism rating scale (CARS) and the autism behavior checklist (ABC). We found that urinary levels of nine of the hydroxy-PAHs were statistically significantly higher in the ASD group, with the exception of 2-hydroxynaphthalene (2-OHNap) and 4-hydroxyphenanthrene (4-OHPhe). Moreover, urinary hydroxy-PAH levels were associated with ASD risk, with odds ratios ranging from 1.86 to 17.19. Exposures to 1-hydroxynaphthalene (1-OHNap,Î2 = 3.32), hydroxyphenanthrenes (1/2/3 + 9-OHPhes,Î2 = 3.41-5.12), 1-hydroxypyrene (1-OH-Pyr;Î2 = 3.91), 2-hydroxybenzofuran (2-OHDBF;Î2 = 3.93), and â‘OH-PAHs (Î2 = 4.67) were positively associated with CARS scores after adjusting for covariates (all p< 0.05). When applying the ABC scale, 1-OHPyr levels were positively associated with ABC total scores (Î2 = 18.54), with the strongest associations evidenced in regard to the social relatedness (Î2 = 6.51) and language domains (Î2 = 6.51) (all p< 0.05). Bayesian kernel machine regression (BKMR) showed consistent positive exposure responses for 1-OHNap, 1-OHPhe, and 3 + 9-OHPhe levels in regard to CARS scores, and for 1-OHPyr levels in regard to ABC total scores. Our findings suggest that children with ASD may have higher urinary levels of hydroxy-PAHs, and that these biomarker levels are associated with an increased odds of ASD, an increased severity of autism symptomology, and increased autistic behaviors in children with autism. LAY SUMMARY: We conducted an epidemiologic study evaluating the associations of urinary hydroxy-PAH levels with autism spectrum disorder (ASD), autism symptomology, and autistic behaviors. We found that urinary hydroxy-PAHs were statistically significantly associated with ASD. We note strong statistically significant associations between 1-OHNap, 1-OHPhe, and 3 + 9-OHPhe levels and increased severity of autism symptomology, as well as a strong statistically significant association between 1-OHPyr levels and behavioral characteristics within the social and linguistic domains. This work, if confirmed, will contribute to the future development of diagnostics for children with mild autism, as well as to environmental measures to promote the health and wellbeing of children with autism spectrum disorders. En ligne : http://dx.doi.org/10.1002/aur.2788 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism Research > 15-10 (October 2022) . - p.1941-1960[article] Association of urinary polycyclic aromatic hydrocarbon metabolites with symptoms among autistic children: A case-control study in Tianjin, China [Texte imprimé et/ou numérique] / Peiying LI, Auteur ; Qiaoyun YANG, Auteur ; Yao LI, Auteur ; Yu HAN, Auteur ; Zhiyi QU, Auteur ; Lei GAO, Auteur ; Tingkai CUI, Auteur ; Wenjuan XIONG, Auteur ; Wei XI, Auteur ; Xin ZHANG, Auteur . - p.1941-1960.
Langues : Anglais (eng)
in Autism Research > 15-10 (October 2022) . - p.1941-1960
Mots-clés : autism spectrum disorder behavioral characteristics case-control study children internal exposure polycyclic aromatic hydrocarbon Index. décimale : PER Périodiques Résumé : Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous pollutants that are associated with altered neurodevelopment and various neurodevelopmental disorders. However, studies evaluating internal biomarkers of PAH exposure in reference to the severity of autism spectrum disorder (ASD) symptomology and autistic behaviors are scarce. Hence, we conducted a case-control study evaluating 12 urinary hydroxylated PAH metabolites (i.e., hydroxy-PAHs) in 101 children with autism and 101 neurotypical children, matching according to sex and age in a 1:1 ratio. In children with ASD, the severity of symptomology and autistic behaviors were assessed using the child autism rating scale (CARS) and the autism behavior checklist (ABC). We found that urinary levels of nine of the hydroxy-PAHs were statistically significantly higher in the ASD group, with the exception of 2-hydroxynaphthalene (2-OHNap) and 4-hydroxyphenanthrene (4-OHPhe). Moreover, urinary hydroxy-PAH levels were associated with ASD risk, with odds ratios ranging from 1.86 to 17.19. Exposures to 1-hydroxynaphthalene (1-OHNap,Î2 = 3.32), hydroxyphenanthrenes (1/2/3 + 9-OHPhes,Î2 = 3.41-5.12), 1-hydroxypyrene (1-OH-Pyr;Î2 = 3.91), 2-hydroxybenzofuran (2-OHDBF;Î2 = 3.93), and â‘OH-PAHs (Î2 = 4.67) were positively associated with CARS scores after adjusting for covariates (all p< 0.05). When applying the ABC scale, 1-OHPyr levels were positively associated with ABC total scores (Î2 = 18.54), with the strongest associations evidenced in regard to the social relatedness (Î2 = 6.51) and language domains (Î2 = 6.51) (all p< 0.05). Bayesian kernel machine regression (BKMR) showed consistent positive exposure responses for 1-OHNap, 1-OHPhe, and 3 + 9-OHPhe levels in regard to CARS scores, and for 1-OHPyr levels in regard to ABC total scores. Our findings suggest that children with ASD may have higher urinary levels of hydroxy-PAHs, and that these biomarker levels are associated with an increased odds of ASD, an increased severity of autism symptomology, and increased autistic behaviors in children with autism. LAY SUMMARY: We conducted an epidemiologic study evaluating the associations of urinary hydroxy-PAH levels with autism spectrum disorder (ASD), autism symptomology, and autistic behaviors. We found that urinary hydroxy-PAHs were statistically significantly associated with ASD. We note strong statistically significant associations between 1-OHNap, 1-OHPhe, and 3 + 9-OHPhe levels and increased severity of autism symptomology, as well as a strong statistically significant association between 1-OHPyr levels and behavioral characteristics within the social and linguistic domains. This work, if confirmed, will contribute to the future development of diagnostics for children with mild autism, as well as to environmental measures to promote the health and wellbeing of children with autism spectrum disorders. En ligne : http://dx.doi.org/10.1002/aur.2788 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 A new model for recognition, referral, and follow-up of autism spectrum disorder: A nationwide program / Onur Burak DURSUN in Autism Research, 15-10 (October 2022)
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[article]
Titre : A new model for recognition, referral, and follow-up of autism spectrum disorder: A nationwide program Type de document : Texte imprimé et/ou numérique Auteurs : Onur Burak DURSUN, Auteur ; Bahadir TURAN, Auteur ; Hakan OGUTLU, Auteur ; Nagihan Cevher BINICI, Auteur ; Abdurrahman Cahid ORENGUL, Auteur ; Esra ALATAS, Auteur ; Rabia Madan OZDEMIR, Auteur ; Elif TASLIBEYAZ, Auteur ; Selçuk KARAMAN, Auteur ; Nahit M. MUKADDES, Auteur ; TURKISH AUTISM WORKGROUP, Auteur Article en page(s) : p.1961-1970 Index. décimale : PER Périodiques Résumé : Abstract Early diagnosis of autism certainly stands as one of the most important determinants to ensure a better prognosis of the disorder, it is common that the screening programs to ensure this, end up not being implemented in health systems of many countries. This may stem from the disadvantages of classically suggested scale-based screening (SBS) programs. This study presents a nationwide recognition and referral model for early diagnosis of autism spectrum disorders (ASD), in order to meet the obvious need for new methods. The model consists of interactive video-based training (IVBAT) of health care workers (HCW), a system where family physicians (FPs) record five probable indicators of autism in their family medicine information system; and is therefore, a practical referral system in which the FP may refer a child with any suggestive finding to a child psychiatrist and may well continue to monitor recently diagnosed cases. The autism teams consist of trained child psychiatrists and coordinators, who delivered trainings to 29,612 FPs and 23,511 nurses countrywide. Of 98.8% FPs were trained throughout the country. Total of 1,863,096 children were reported to have a brief examination of autism signs in Family Medicine Units by trained FPs and nurses. A total of 55,314 (2.96%) these children were deemed at risk for ASD and were referred to child psychiatrists. In the evaluation of 55,314 children by child psychiatrists, 10,087 cases were diagnosed with developmental disorders, while 3226 of children at risk were diagnosed with autism. The results of this study, which reached to the largest sample to date, suggest that some other alternative methods, in addition to SBS should also be tested in order to screen ASD. Lay Summary In this study, a nationwide recognition and referral model for early identification of autism spectrum disorders (ASD) is presented. Scale-based screening (SBS) is the most recommended model for autism, however, it is clear that most countries can not implement this model in their health system. The results of this study, which reached to the largest sample to date, suggest that SBS may not be the only me for screening ASD and that alternative methods should be tried, as there is an obvious need for exploratory approaches. En ligne : https://doi.org/10.1002/aur.2813 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism Research > 15-10 (October 2022) . - p.1961-1970[article] A new model for recognition, referral, and follow-up of autism spectrum disorder: A nationwide program [Texte imprimé et/ou numérique] / Onur Burak DURSUN, Auteur ; Bahadir TURAN, Auteur ; Hakan OGUTLU, Auteur ; Nagihan Cevher BINICI, Auteur ; Abdurrahman Cahid ORENGUL, Auteur ; Esra ALATAS, Auteur ; Rabia Madan OZDEMIR, Auteur ; Elif TASLIBEYAZ, Auteur ; Selçuk KARAMAN, Auteur ; Nahit M. MUKADDES, Auteur ; TURKISH AUTISM WORKGROUP, Auteur . - p.1961-1970.
in Autism Research > 15-10 (October 2022) . - p.1961-1970
Index. décimale : PER Périodiques Résumé : Abstract Early diagnosis of autism certainly stands as one of the most important determinants to ensure a better prognosis of the disorder, it is common that the screening programs to ensure this, end up not being implemented in health systems of many countries. This may stem from the disadvantages of classically suggested scale-based screening (SBS) programs. This study presents a nationwide recognition and referral model for early diagnosis of autism spectrum disorders (ASD), in order to meet the obvious need for new methods. The model consists of interactive video-based training (IVBAT) of health care workers (HCW), a system where family physicians (FPs) record five probable indicators of autism in their family medicine information system; and is therefore, a practical referral system in which the FP may refer a child with any suggestive finding to a child psychiatrist and may well continue to monitor recently diagnosed cases. The autism teams consist of trained child psychiatrists and coordinators, who delivered trainings to 29,612 FPs and 23,511 nurses countrywide. Of 98.8% FPs were trained throughout the country. Total of 1,863,096 children were reported to have a brief examination of autism signs in Family Medicine Units by trained FPs and nurses. A total of 55,314 (2.96%) these children were deemed at risk for ASD and were referred to child psychiatrists. In the evaluation of 55,314 children by child psychiatrists, 10,087 cases were diagnosed with developmental disorders, while 3226 of children at risk were diagnosed with autism. The results of this study, which reached to the largest sample to date, suggest that some other alternative methods, in addition to SBS should also be tested in order to screen ASD. Lay Summary In this study, a nationwide recognition and referral model for early identification of autism spectrum disorders (ASD) is presented. Scale-based screening (SBS) is the most recommended model for autism, however, it is clear that most countries can not implement this model in their health system. The results of this study, which reached to the largest sample to date, suggest that SBS may not be the only me for screening ASD and that alternative methods should be tried, as there is an obvious need for exploratory approaches. En ligne : https://doi.org/10.1002/aur.2813 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 The effectiveness of an attention-based intervention for school-aged autistic children with anger regulating problems: A randomized controlled trial / Pamela CLIFFORD in Autism Research, 15-10 (October 2022)
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[article]
Titre : The effectiveness of an attention-based intervention for school-aged autistic children with anger regulating problems: A randomized controlled trial Type de document : Texte imprimé et/ou numérique Auteurs : Pamela CLIFFORD, Auteur ; Carolien GEVERS, Auteur ; Kim M. JONKMAN, Auteur ; Frits BOER, Auteur ; Sander BEGEER, Auteur Article en page(s) : p.1971-1984 Langues : Anglais (eng) Mots-clés : Affect/emotion Behavioral intervention Children Clinical Trials Intervention Treatment research Index. décimale : PER Périodiques Résumé : Anger regulation is a challenge for children with autism spectrum disorders (ASD). We investigated if attention-based cognitive behavioral treatment, based on mindfulness cognitive therapy (MBCT) and dialectical behavior therapy (DBT), reduces aggressive behavior and improves anger coping in school-aged autistic children (n = 51). Children were randomized to an active-control or a treatment condition. The treatment included nine weekly sessions attention-based individual therapy. Parents in both conditions received three weekly psychoeducation group sessions to heighten awareness of expressed emotion (EE). For aggressive behavior, treatment reduced temper tantrums and arguing. No effect was found on destroying things and physical violence. For anger coping, treatment increased adaptive coping strategies of diffusion and social support seeking, but had no effect on assertion, rumination, and maladaptive coping direct anger out and avoidance. Treatment did not impact secondary outcome measures concerning children's quality of life (QoL) and parental stress-levels and psychological well-being. In conclusion, school-aged autistic children are able to acquire self-regulation skills reducing temper tantrums and arguing and increasing the use of adaptive anger coping strategies. The intervention shows potential to improve behavior and regulation, but little transfer to other domains. Limitations and future directions involving the child's social environment, including parents, siblings, and teachers are discussed. LAY SUMMARY: Children on the autism spectrum often show aggressive behavior. Treatment can train children to be more aware of their emotions. This study found that this can help reducing temper tantrums and arguing and increasing some coping skills, though no impact was found on several other domains of aggression and coping. En ligne : http://dx.doi.org/10.1002/aur.2800 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism Research > 15-10 (October 2022) . - p.1971-1984[article] The effectiveness of an attention-based intervention for school-aged autistic children with anger regulating problems: A randomized controlled trial [Texte imprimé et/ou numérique] / Pamela CLIFFORD, Auteur ; Carolien GEVERS, Auteur ; Kim M. JONKMAN, Auteur ; Frits BOER, Auteur ; Sander BEGEER, Auteur . - p.1971-1984.
Langues : Anglais (eng)
in Autism Research > 15-10 (October 2022) . - p.1971-1984
Mots-clés : Affect/emotion Behavioral intervention Children Clinical Trials Intervention Treatment research Index. décimale : PER Périodiques Résumé : Anger regulation is a challenge for children with autism spectrum disorders (ASD). We investigated if attention-based cognitive behavioral treatment, based on mindfulness cognitive therapy (MBCT) and dialectical behavior therapy (DBT), reduces aggressive behavior and improves anger coping in school-aged autistic children (n = 51). Children were randomized to an active-control or a treatment condition. The treatment included nine weekly sessions attention-based individual therapy. Parents in both conditions received three weekly psychoeducation group sessions to heighten awareness of expressed emotion (EE). For aggressive behavior, treatment reduced temper tantrums and arguing. No effect was found on destroying things and physical violence. For anger coping, treatment increased adaptive coping strategies of diffusion and social support seeking, but had no effect on assertion, rumination, and maladaptive coping direct anger out and avoidance. Treatment did not impact secondary outcome measures concerning children's quality of life (QoL) and parental stress-levels and psychological well-being. In conclusion, school-aged autistic children are able to acquire self-regulation skills reducing temper tantrums and arguing and increasing the use of adaptive anger coping strategies. The intervention shows potential to improve behavior and regulation, but little transfer to other domains. Limitations and future directions involving the child's social environment, including parents, siblings, and teachers are discussed. LAY SUMMARY: Children on the autism spectrum often show aggressive behavior. Treatment can train children to be more aware of their emotions. This study found that this can help reducing temper tantrums and arguing and increasing some coping skills, though no impact was found on several other domains of aggression and coping. En ligne : http://dx.doi.org/10.1002/aur.2800 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 The impact of prefrontal transcranial direct current stimulation (tDCS) on theory of mind, emotion regulation and emotional-behavioral functions in children with autism disorder: A randomized, sham-controlled, and parallel-group study / Mehdi ZEMESTANI in Autism Research, 15-10 (October 2022)
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[article]
Titre : The impact of prefrontal transcranial direct current stimulation (tDCS) on theory of mind, emotion regulation and emotional-behavioral functions in children with autism disorder: A randomized, sham-controlled, and parallel-group study Type de document : Texte imprimé et/ou numérique Auteurs : Mehdi ZEMESTANI, Auteur ; Omid HOSEINPANAHI, Auteur ; Mohammad Ali SALEHINEJAD, Auteur ; Michael A. NITSCHE, Auteur Article en page(s) : p.1985-2003 Langues : Anglais (eng) Mots-clés : autism spectrum disorder dorsolateral prefrontal cortex emotion regulation theory of mind transcranial direct current stimulation Index. décimale : PER Périodiques Résumé : Advances in our knowledge about the neuropsychological mechanisms underlying core deficits in autism spectrum disorder (ASD) have produced several novel treatment modalities. One of these approaches is modulation of activity of the brain regions involved in ASD symptoms. This study examined the effects of transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex (DLPFC) on autism symptom severity, theory of mind, emotion regulation strategies, and emotional-behavioral functions in children with ASD. Thirty-two children (M(age) = 10.16, SD = 1.93, range 7-12 years) diagnosed with ASD were randomly assigned to active (N = 17) or sham stimulation (N = 15) groups in a randomized, sham-controlled, parallel-group design. Participants underwent 10 sessions of active (1.5 mA, 15 min, bilateral left anodal/right cathodal DLPFC, 2 sessions per week) or sham tDCS. Autism symptom severity, theory of mind, emotion regulation strategies, and emotional-behavioral functioning of the patients were assessed at baseline, immediately after the intervention, and 1 month after the intervention. A significant improvement of autism symptom severity (i.e., communication), theory of mind (i.e., ToM 3), and emotion regulation strategies was observed for the active as compared to the sham stimulation group at the end of the intervention, and these effects were maintained at the one-month follow-up. The results suggest that repeated tDCS with anodal stimulation of left and cathodal stimulation of right DLPFC improves autism symptom severity as well as social cognition and emotion regulation in ASD. LAY SUMMARY: Previous research has suggested that targeting core mechanisms underlying cognitive-emotional and behavioral deficits of autistic children might improve symptoms of ASD. Deficient social and behavioral functioning, impaired theory of mind, and emotional regulation deficits have been identified as core treatment targets for this group. Specific subregions of the prefrontal cortex are involved in these deficits, including hypoactivity of the dorsolateral prefrontal cortex (DLPFC). Upregulation of this area with non-invasive brain stimulation, namely anodal transcranial direct current stimulation (tDCS), results in improved social and behavioral functioning in children with ASD. Very few studies have however examined the effects of this intervention on theory of mind, emotional regulation, and emotional-behavioral problems. We examined the effects of anodal tDCS over the left DLPFC (F3), combined with cathodal tDCS over the right DLPFC (F4) on autism symptom severity as well as theory of mind, emotional regulation, and emotional-behavioral problems of children with ASD. This intervention improved autism symptom severity, specific domains of theory of mind, and emotion regulation. These findings have clinical implications for the treatment of ASD and suggest that targeting core mechanisms underlying socio-cognitive-emotional deficits of autistic children using tDCS might improve symptoms of ASD. En ligne : http://dx.doi.org/10.1002/aur.2803 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism Research > 15-10 (October 2022) . - p.1985-2003[article] The impact of prefrontal transcranial direct current stimulation (tDCS) on theory of mind, emotion regulation and emotional-behavioral functions in children with autism disorder: A randomized, sham-controlled, and parallel-group study [Texte imprimé et/ou numérique] / Mehdi ZEMESTANI, Auteur ; Omid HOSEINPANAHI, Auteur ; Mohammad Ali SALEHINEJAD, Auteur ; Michael A. NITSCHE, Auteur . - p.1985-2003.
Langues : Anglais (eng)
in Autism Research > 15-10 (October 2022) . - p.1985-2003
Mots-clés : autism spectrum disorder dorsolateral prefrontal cortex emotion regulation theory of mind transcranial direct current stimulation Index. décimale : PER Périodiques Résumé : Advances in our knowledge about the neuropsychological mechanisms underlying core deficits in autism spectrum disorder (ASD) have produced several novel treatment modalities. One of these approaches is modulation of activity of the brain regions involved in ASD symptoms. This study examined the effects of transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex (DLPFC) on autism symptom severity, theory of mind, emotion regulation strategies, and emotional-behavioral functions in children with ASD. Thirty-two children (M(age) = 10.16, SD = 1.93, range 7-12 years) diagnosed with ASD were randomly assigned to active (N = 17) or sham stimulation (N = 15) groups in a randomized, sham-controlled, parallel-group design. Participants underwent 10 sessions of active (1.5 mA, 15 min, bilateral left anodal/right cathodal DLPFC, 2 sessions per week) or sham tDCS. Autism symptom severity, theory of mind, emotion regulation strategies, and emotional-behavioral functioning of the patients were assessed at baseline, immediately after the intervention, and 1 month after the intervention. A significant improvement of autism symptom severity (i.e., communication), theory of mind (i.e., ToM 3), and emotion regulation strategies was observed for the active as compared to the sham stimulation group at the end of the intervention, and these effects were maintained at the one-month follow-up. The results suggest that repeated tDCS with anodal stimulation of left and cathodal stimulation of right DLPFC improves autism symptom severity as well as social cognition and emotion regulation in ASD. LAY SUMMARY: Previous research has suggested that targeting core mechanisms underlying cognitive-emotional and behavioral deficits of autistic children might improve symptoms of ASD. Deficient social and behavioral functioning, impaired theory of mind, and emotional regulation deficits have been identified as core treatment targets for this group. Specific subregions of the prefrontal cortex are involved in these deficits, including hypoactivity of the dorsolateral prefrontal cortex (DLPFC). Upregulation of this area with non-invasive brain stimulation, namely anodal transcranial direct current stimulation (tDCS), results in improved social and behavioral functioning in children with ASD. Very few studies have however examined the effects of this intervention on theory of mind, emotional regulation, and emotional-behavioral problems. We examined the effects of anodal tDCS over the left DLPFC (F3), combined with cathodal tDCS over the right DLPFC (F4) on autism symptom severity as well as theory of mind, emotional regulation, and emotional-behavioral problems of children with ASD. This intervention improved autism symptom severity, specific domains of theory of mind, and emotion regulation. These findings have clinical implications for the treatment of ASD and suggest that targeting core mechanisms underlying socio-cognitive-emotional deficits of autistic children using tDCS might improve symptoms of ASD. En ligne : http://dx.doi.org/10.1002/aur.2803 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488