Dépouillements

Exploring social cognition and romantic self-efficacy in autistic young adults: Better social awareness is associated with lower confidence / Isabella SCHICHTER in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102466 Titre : Exploring social cognition and romantic self-efficacy in autistic young adults: Better social awareness is associated with lower confidence Type de document : Texte imprimé et/ou numérique Auteurs : Isabella SCHICHTER, Auteur ; Nicole NADWODNY, Auteur ; Brooke H. KOHN, Auteur ; Dhruval THAKKAR, Auteur ; David W. PANTALONE, Auteur ; Susan FAJA, Auteur Article en page(s) : 102466 Langues : Anglais (eng) Mots-clés : Autism  Social Cognition  Self-efficacy  Perceived knowledge  Dating  Romantic Relationships Index. décimale : PER Périodiques Résumé : Background Despite misconceptions, autistic young adults are interested in romantic relationships (Fernandes et al., 2016, Hancock, Stokes, & Mesibov, 2019, Mehzabin and Stokes, 2011). Research is needed to better understand how the social characteristics of autism impact romantic relationship experiences, knowledge of sexual health, and confidence in one?s own abilities. Social cognition skills are linked to functioning in interpersonal relationships and are important for understanding the mental states of others. The present research aims to explore the intersections among social cognition skills, romantic self-efficacy, perceived knowledge, and dating outcomes. We hypothesize that social cognition level, self-efficacy, perceived knowledge, and romantic relationship outcomes will be positively related. Method Verbal autistic young adults (N = 31) aged 18-26 years participated in a study aimed at investigating the romantic experiences of young autistic adults. Participants completed questionnaires on self-efficacy and perceived knowledge, as well as a battery of social cognition tasks, including assessments of spontaneous and non-spontaneous social cognition. Results Spontaneous social cognition was negatively correlated with both relationship self-efficacy and perceived knowledge. Perceived knowledge, actual knowledge, and self-efficacy were positively correlated with each other. Conclusion This exploratory study was the first of which we are aware to demonstrate that autistic adults with stronger spontaneous social awareness are less confident of their sexual knowledge and abilities in romantic relationships than autistic adults with weaker spontaneous awareness. These findings suggest social cognitive tasks could be useful in assessing the specific sexual and romantic health-education needs of young autistic adults. En ligne : https://doi.org/10.1016/j.rasd.2024.102466 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=539 [article] Exploring social cognition and romantic self-efficacy in autistic young adults: Better social awareness is associated with lower confidence [Texte imprimé et/ou numérique] / Isabella SCHICHTER, Auteur ; Nicole NADWODNY, Auteur ; Brooke H. KOHN, Auteur ; Dhruval THAKKAR, Auteur ; David W. PANTALONE, Auteur ; Susan FAJA, Auteur . - 102466. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102466 Mots-clés : Autism  Social Cognition  Self-efficacy  Perceived knowledge  Dating  Romantic Relationships Index. décimale : PER Périodiques Résumé : Background Despite misconceptions, autistic young adults are interested in romantic relationships (Fernandes et al., 2016, Hancock, Stokes, & Mesibov, 2019, Mehzabin and Stokes, 2011). Research is needed to better understand how the social characteristics of autism impact romantic relationship experiences, knowledge of sexual health, and confidence in one?s own abilities. Social cognition skills are linked to functioning in interpersonal relationships and are important for understanding the mental states of others. The present research aims to explore the intersections among social cognition skills, romantic self-efficacy, perceived knowledge, and dating outcomes. We hypothesize that social cognition level, self-efficacy, perceived knowledge, and romantic relationship outcomes will be positively related. Method Verbal autistic young adults (N = 31) aged 18-26 years participated in a study aimed at investigating the romantic experiences of young autistic adults. Participants completed questionnaires on self-efficacy and perceived knowledge, as well as a battery of social cognition tasks, including assessments of spontaneous and non-spontaneous social cognition. Results Spontaneous social cognition was negatively correlated with both relationship self-efficacy and perceived knowledge. Perceived knowledge, actual knowledge, and self-efficacy were positively correlated with each other. Conclusion This exploratory study was the first of which we are aware to demonstrate that autistic adults with stronger spontaneous social awareness are less confident of their sexual knowledge and abilities in romantic relationships than autistic adults with weaker spontaneous awareness. These findings suggest social cognitive tasks could be useful in assessing the specific sexual and romantic health-education needs of young autistic adults. En ligne : https://doi.org/10.1016/j.rasd.2024.102466 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=539

Potential brain biomarkers in patients with Autism spectrum syndrome / Davood GHAVI in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102467 Titre : Potential brain biomarkers in patients with Autism spectrum syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Davood GHAVI, Auteur ; Amir EBRAHIMI, Auteur ; Zahra FOROUZANDEH, Auteur ; Mahmoud SHEKARI KHANIANI, Auteur ; Sima MANSOORI DERAKHSHAN, Auteur Article en page(s) : 102467 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Differentially expressed genes  Microarray  Biomarker Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is referred as a cluster of neurodevelopmental disorders with relatively high incidence. ASD is believed to be a multifactorial condition, and genetics is one of the most important factors in its formation. Therefore, profiling gene expression in ASD patients can lead to the identification of new molecular insights. To evaluate gene expression patterns, we have utilized NCBI GEO microarray data. The dataset of ASD patients (GSE28475, GSE28521, GSE38322 and GSE113834) were defined as two meta-data, Total brain meta-data and Lobe specified meta-data. Meta-analysis and batch effect removal was conducted by the SVA package. Microarray data analysis was performed using the LIMMA package under R 4.2.1 software. Total Meta-Analysis (TMA) identified 525 significantly differentially expressed genes (DEGs) in ASD patient?s brain. The temporal and frontal lobes of ASD patients showed 96 and 23 DEGs respectively. Among the mentioned DEGs, there were 11 common DEGs between the temporal and frontal lobes that were also dysregulated in TMA except for UTP4 which was only dysregulated in the temporal and frontal lobes. However, the occipital and cerebellum lobes did not show any significant DEGs. Enrichment analysis pointed out the vital roles of identified DEGs in transmembrane transportation, ATP production, and cellular respiration. According to our findings, gene expression profile in the temporal and frontal lobes of ASD patients are significantly different than a control group. This aberrant gene expression potentially leads to crucial complications in nerve signal transmission and defects energy production in neurons. Therefore, potential therapeutic targets may be suggested based on these findings. En ligne : https://doi.org/10.1016/j.rasd.2024.102467 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Potential brain biomarkers in patients with Autism spectrum syndrome [Texte imprimé et/ou numérique] / Davood GHAVI, Auteur ; Amir EBRAHIMI, Auteur ; Zahra FOROUZANDEH, Auteur ; Mahmoud SHEKARI KHANIANI, Auteur ; Sima MANSOORI DERAKHSHAN, Auteur . - 102467. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102467 Mots-clés : Autism spectrum disorders  Differentially expressed genes  Microarray  Biomarker Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is referred as a cluster of neurodevelopmental disorders with relatively high incidence. ASD is believed to be a multifactorial condition, and genetics is one of the most important factors in its formation. Therefore, profiling gene expression in ASD patients can lead to the identification of new molecular insights. To evaluate gene expression patterns, we have utilized NCBI GEO microarray data. The dataset of ASD patients (GSE28475, GSE28521, GSE38322 and GSE113834) were defined as two meta-data, Total brain meta-data and Lobe specified meta-data. Meta-analysis and batch effect removal was conducted by the SVA package. Microarray data analysis was performed using the LIMMA package under R 4.2.1 software. Total Meta-Analysis (TMA) identified 525 significantly differentially expressed genes (DEGs) in ASD patient?s brain. The temporal and frontal lobes of ASD patients showed 96 and 23 DEGs respectively. Among the mentioned DEGs, there were 11 common DEGs between the temporal and frontal lobes that were also dysregulated in TMA except for UTP4 which was only dysregulated in the temporal and frontal lobes. However, the occipital and cerebellum lobes did not show any significant DEGs. Enrichment analysis pointed out the vital roles of identified DEGs in transmembrane transportation, ATP production, and cellular respiration. According to our findings, gene expression profile in the temporal and frontal lobes of ASD patients are significantly different than a control group. This aberrant gene expression potentially leads to crucial complications in nerve signal transmission and defects energy production in neurons. Therefore, potential therapeutic targets may be suggested based on these findings. En ligne : https://doi.org/10.1016/j.rasd.2024.102467 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Predicting longitudinal trajectories of adaptive couple processes in families of autistic children: Applying the Vulnerability Stress Adaptation model / Hillary K. SCHILTZ in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102468 Titre : Predicting longitudinal trajectories of adaptive couple processes in families of autistic children: Applying the Vulnerability Stress Adaptation model Type de document : Texte imprimé et/ou numérique Auteurs : Hillary K. SCHILTZ, Auteur ; Amy Vaughan VAN HECKE, Auteur ; Jennifer M. Putney, Auteur ; Sigan L. HARTLEY, Auteur Article en page(s) : 102468 Langues : Anglais (eng) Mots-clés : Adaptive processes  Vulnerability Stress Adaptation model  Autism  Parenting stress  Problem-solving  Couple relationships Index. décimale : PER Périodiques Résumé : Background Many couples raising an autistic child report long-standing and thriving couple relationships, even within the context of elevated parenting stress. Little is known however, about the factors that promote or hinder adaptive couple processes or how these processes may shift over time. Drawing on the Vulnerability Stress Adaptation (VSA) model, the present study examined adaptive couple problem-solving processes across three years and the extent to which these processes were predicted by parent broader autism phenotype (BAP) and level of parenting stress in couples raising an autistic child. Method In total, 189 couples (378 parents) raising an autistic child (aged 5-12 years) completed questionnaires assessing parent BAP and level of parenting stress. Couples also engaged in observed problem-solving interactions at four time points spanning three years. Results The use of adaptive couple problem-solving behaviors (Solution Focused Reciprocity and Positive Teamwork) declined linearly across time. Father BAP predicted greater decline in these adaptive processes (Solution Focused Reciprocity and Positive Teamwork), particularly when mother-reported parenting stress was low. No main effects of parenting stress on change in adaptive couple problem-solving behaviors emerged. Conclusions Findings highlight the utility of the VSA Model for understanding the short-term longitudinal course of problem-solving behaviors in couples raising an autistic school-aged child. This study can inform efforts to promote healthy and long-lasting couple relationships in this population. En ligne : https://doi.org/10.1016/j.rasd.2024.102468 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Predicting longitudinal trajectories of adaptive couple processes in families of autistic children: Applying the Vulnerability Stress Adaptation model [Texte imprimé et/ou numérique] / Hillary K. SCHILTZ, Auteur ; Amy Vaughan VAN HECKE, Auteur ; Jennifer M. Putney, Auteur ; Sigan L. HARTLEY, Auteur . - 102468. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102468 Mots-clés : Adaptive processes  Vulnerability Stress Adaptation model  Autism  Parenting stress  Problem-solving  Couple relationships Index. décimale : PER Périodiques Résumé : Background Many couples raising an autistic child report long-standing and thriving couple relationships, even within the context of elevated parenting stress. Little is known however, about the factors that promote or hinder adaptive couple processes or how these processes may shift over time. Drawing on the Vulnerability Stress Adaptation (VSA) model, the present study examined adaptive couple problem-solving processes across three years and the extent to which these processes were predicted by parent broader autism phenotype (BAP) and level of parenting stress in couples raising an autistic child. Method In total, 189 couples (378 parents) raising an autistic child (aged 5-12 years) completed questionnaires assessing parent BAP and level of parenting stress. Couples also engaged in observed problem-solving interactions at four time points spanning three years. Results The use of adaptive couple problem-solving behaviors (Solution Focused Reciprocity and Positive Teamwork) declined linearly across time. Father BAP predicted greater decline in these adaptive processes (Solution Focused Reciprocity and Positive Teamwork), particularly when mother-reported parenting stress was low. No main effects of parenting stress on change in adaptive couple problem-solving behaviors emerged. Conclusions Findings highlight the utility of the VSA Model for understanding the short-term longitudinal course of problem-solving behaviors in couples raising an autistic school-aged child. This study can inform efforts to promote healthy and long-lasting couple relationships in this population. En ligne : https://doi.org/10.1016/j.rasd.2024.102468 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Factor analysis of the feeding and eating in AutiSm Together Assessment / Karla K. AUSDERAU in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102469 Titre : Factor analysis of the feeding and eating in AutiSm Together Assessment Type de document : Texte imprimé et/ou numérique Auteurs : Karla K. AUSDERAU, Auteur ; Brittany M. St JOHN, Auteur ; Muhammad O. AL-HEIZAN, Auteur ; Caitlin DAMMANN, Auteur ; Sarah CHAUDOIR, Auteur ; John SIDERIS, Auteur Article en page(s) : 102469 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Feeding  Factor analysis  Assessment  Sensory  Oral motor  Gastrointestinal  Behavior Index. décimale : PER Périodiques Résumé : Background Autistic children experience high rates of feeding challenges, negatively affecting their.health, eating patterns, and social eating experiences. The Feeding and Eating in AutiSm Together; FEAST, a caregiver-report questionnaire, was developed to characterize feeding challenges in autistic children ages 2 to 12 years. The purpose of this study is to determine the construct validity of the FEAST assessment using a large national sample of autistic children. Method A large national sample (N = 396) of caregivers completed the online survey. An ordinal confirmatory factor model using a robust weighted least squares approach validated the four predicted groupings of feeding challenges (sensory processing; behavior; oral.motor skills; and gastrointestinal) with generally strong loadings onto the four distinct.factors. Results Model fit statistics indicated good model fit (Robust Root Mean Square Error of.Approximation=.080, Robust Comparative Fit Index =.909, Robust Tucker-Lewis.Index=.901) Findings provide preliminary confirmation of the construct validity of the.FEAST assessment to characterize feeding difficulties for autistic children ages 2-12. Small to medium correlations between all factors indicate items successfully targeted.four unique areas of feeding challenge. For all factors, the largest correlation was with.behavior. Conclusion Assessments developed to address the complex feeding and mealtime challenges for.autistic children are essential to identify and integrate the most appropriate intervention.approaches. FEAST offers researchers and clinicians with a comprehensive and psychometrically sound assessment tool to address autistic children?s unique feeding.challenges. En ligne : https://doi.org/10.1016/j.rasd.2024.102469 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Factor analysis of the feeding and eating in AutiSm Together Assessment [Texte imprimé et/ou numérique] / Karla K. AUSDERAU, Auteur ; Brittany M. St JOHN, Auteur ; Muhammad O. AL-HEIZAN, Auteur ; Caitlin DAMMANN, Auteur ; Sarah CHAUDOIR, Auteur ; John SIDERIS, Auteur . - 102469. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102469 Mots-clés : Autism spectrum disorder  Feeding  Factor analysis  Assessment  Sensory  Oral motor  Gastrointestinal  Behavior Index. décimale : PER Périodiques Résumé : Background Autistic children experience high rates of feeding challenges, negatively affecting their.health, eating patterns, and social eating experiences. The Feeding and Eating in AutiSm Together; FEAST, a caregiver-report questionnaire, was developed to characterize feeding challenges in autistic children ages 2 to 12 years. The purpose of this study is to determine the construct validity of the FEAST assessment using a large national sample of autistic children. Method A large national sample (N = 396) of caregivers completed the online survey. An ordinal confirmatory factor model using a robust weighted least squares approach validated the four predicted groupings of feeding challenges (sensory processing; behavior; oral.motor skills; and gastrointestinal) with generally strong loadings onto the four distinct.factors. Results Model fit statistics indicated good model fit (Robust Root Mean Square Error of.Approximation=.080, Robust Comparative Fit Index =.909, Robust Tucker-Lewis.Index=.901) Findings provide preliminary confirmation of the construct validity of the.FEAST assessment to characterize feeding difficulties for autistic children ages 2-12. Small to medium correlations between all factors indicate items successfully targeted.four unique areas of feeding challenge. For all factors, the largest correlation was with.behavior. Conclusion Assessments developed to address the complex feeding and mealtime challenges for.autistic children are essential to identify and integrate the most appropriate intervention.approaches. FEAST offers researchers and clinicians with a comprehensive and psychometrically sound assessment tool to address autistic children?s unique feeding.challenges. En ligne : https://doi.org/10.1016/j.rasd.2024.102469 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Sensory responsivity and its relation to alexithymia, social processing and restricted interests and repetitive behaviour in autistic children / Madeleine DIEPMAN in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102470 Titre : Sensory responsivity and its relation to alexithymia, social processing and restricted interests and repetitive behaviour in autistic children Type de document : Texte imprimé et/ou numérique Auteurs : Madeleine DIEPMAN, Auteur ; Nuala BRADY, Auteur Article en page(s) : 102470 Langues : Anglais (eng) Mots-clés : Autism  Alexithymia  Sensory responsivity  Hyper-responsivity  Emotions  Predictive coding Index. décimale : PER Périodiques Résumé : Background Although noted in the earliest descriptions of autism, differences in sensory processing, including hyper-responsivity, hypo-responsivity and sensory seeking, have only been included as a diagnostic criterion more recently. Understanding how these unique features of sensory processing are related to the emotional and social aspects of autism is an ongoing question. Here we ask whether differences in sensory processing are associated with alexithymia, a trait characterised by an inability to identify and describe one?s feelings, which has a high incidence in autism. Method Parents of autistic children (n = 38) and parents of non-autistic children (n = 35) completed four standardized scales, the Short Sensory Profile-2, Social Responsiveness Scale-2, Social Communication Questionnaire, and the Children?s Alexithymia Measure. Results Across all four scales the autistic children showed higher scores than the non-autistic children, with large effect sizes. Using the subscales of the SSP-2 we show that, for the autistic children but not for the non-autistic children, sensory hyper-responsivity is predictive of alexithymia, of core social features of autism and of restricted interests and repetitive behaviour (RIRB), after controlling for hypo-responsivity and sensory seeking. Conclusions These results add to a small but growing literature on the relationship between sensory processing and social and emotional behaviours in autistic children, and are discussed with reference to predictive coding and 'sensory first' accounts of autism. As sensory differences in autism impact children?s daily functioning and educational opportunities, understanding how these differences relate to social and emotional behaviour is important. En ligne : https://doi.org/10.1016/j.rasd.2024.102470 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Sensory responsivity and its relation to alexithymia, social processing and restricted interests and repetitive behaviour in autistic children [Texte imprimé et/ou numérique] / Madeleine DIEPMAN, Auteur ; Nuala BRADY, Auteur . - 102470. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102470 Mots-clés : Autism  Alexithymia  Sensory responsivity  Hyper-responsivity  Emotions  Predictive coding Index. décimale : PER Périodiques Résumé : Background Although noted in the earliest descriptions of autism, differences in sensory processing, including hyper-responsivity, hypo-responsivity and sensory seeking, have only been included as a diagnostic criterion more recently. Understanding how these unique features of sensory processing are related to the emotional and social aspects of autism is an ongoing question. Here we ask whether differences in sensory processing are associated with alexithymia, a trait characterised by an inability to identify and describe one?s feelings, which has a high incidence in autism. Method Parents of autistic children (n = 38) and parents of non-autistic children (n = 35) completed four standardized scales, the Short Sensory Profile-2, Social Responsiveness Scale-2, Social Communication Questionnaire, and the Children?s Alexithymia Measure. Results Across all four scales the autistic children showed higher scores than the non-autistic children, with large effect sizes. Using the subscales of the SSP-2 we show that, for the autistic children but not for the non-autistic children, sensory hyper-responsivity is predictive of alexithymia, of core social features of autism and of restricted interests and repetitive behaviour (RIRB), after controlling for hypo-responsivity and sensory seeking. Conclusions These results add to a small but growing literature on the relationship between sensory processing and social and emotional behaviours in autistic children, and are discussed with reference to predictive coding and 'sensory first' accounts of autism. As sensory differences in autism impact children?s daily functioning and educational opportunities, understanding how these differences relate to social and emotional behaviour is important. En ligne : https://doi.org/10.1016/j.rasd.2024.102470 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Biological determinants of the origin and development of the opposite psychological and behavioral traits associated with autism spectrum disorders and Williams syndrome / Klara VERNEROVA in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102479 Titre : Biological determinants of the origin and development of the opposite psychological and behavioral traits associated with autism spectrum disorders and Williams syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Klara VERNEROVA, Auteur ; Roman SOLC, Auteur Article en page(s) : 102479 Langues : Anglais (eng) Mots-clés : Williams syndrome  Autism spectrum disorders  Duplication 7q11.23 syndrome  TFII-I genetic family  Hyperserotonemia  Timothy syndrome Index. décimale : PER Périodiques Résumé : Williams syndrome is a genetical disorder caused by microdeletion on chromosome 7, specifically of 7q11.23 region. Its phenotype is characterized by typical facial features, mild mental retardation, cardiovascular problems (patients often suffer from supravalvular aortic stenosis), gastrointestinal problems and endocrine abnormalities. However, Williams syndrome is best known for its unique behavioural-cognitive profile which leads to friendly, hypersocial and talkative personality. This specific neuropsychological profile is repeatedly considered to be the right opposite of the psychological profile, which is characteristic for people with autism spectrum disorder. Individuals with autism spectrum disorder often have severe impairments in social interaction, communication and they suffer from social anxieties. This contrasting cognitive-behavioural phenotype inspired many studies to examine possible biological causes, which might determine given personality features. Several results from these studies suggest that small genetical TFII-I family, which lies in the critical Williams syndrome region, could have a significant impact on the extent of personality qualities such as sociality and communication. En ligne : https://doi.org/10.1016/j.rasd.2024.102479 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Biological determinants of the origin and development of the opposite psychological and behavioral traits associated with autism spectrum disorders and Williams syndrome [Texte imprimé et/ou numérique] / Klara VERNEROVA, Auteur ; Roman SOLC, Auteur . - 102479. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102479 Mots-clés : Williams syndrome  Autism spectrum disorders  Duplication 7q11.23 syndrome  TFII-I genetic family  Hyperserotonemia  Timothy syndrome Index. décimale : PER Périodiques Résumé : Williams syndrome is a genetical disorder caused by microdeletion on chromosome 7, specifically of 7q11.23 region. Its phenotype is characterized by typical facial features, mild mental retardation, cardiovascular problems (patients often suffer from supravalvular aortic stenosis), gastrointestinal problems and endocrine abnormalities. However, Williams syndrome is best known for its unique behavioural-cognitive profile which leads to friendly, hypersocial and talkative personality. This specific neuropsychological profile is repeatedly considered to be the right opposite of the psychological profile, which is characteristic for people with autism spectrum disorder. Individuals with autism spectrum disorder often have severe impairments in social interaction, communication and they suffer from social anxieties. This contrasting cognitive-behavioural phenotype inspired many studies to examine possible biological causes, which might determine given personality features. Several results from these studies suggest that small genetical TFII-I family, which lies in the critical Williams syndrome region, could have a significant impact on the extent of personality qualities such as sociality and communication. En ligne : https://doi.org/10.1016/j.rasd.2024.102479 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Comparison of the oral microbiota of children with autism spectrum disorder in primary dentition with neurotypical controls / Gülsevim ODA in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102480 Titre : Comparison of the oral microbiota of children with autism spectrum disorder in primary dentition with neurotypical controls Type de document : Texte imprimé et/ou numérique Auteurs : Gülsevim ODA, Auteur ; Deniz Ece KAYA, Auteur ; Tuba Bilbay KAYNAR, Auteur ; Emine Nursen TOPCUO?LU, Auteur ; Murat CO?KUN, Auteur ; Gamze AREN, Auteur Article en page(s) : 102480 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Microbiota analysis  Saliva Index. décimale : PER Périodiques Résumé : Background The number of studies suggesting differences in oral microbiota in autism spectrum disorders (ASDs) is increasing. However, the relationship between oral microbiota and ASD has not been determined. Therefore, this study aimed to examine the oral microbiota of children with ASD compared with neurotypical controls. Method Nine boys with a diagnosis of ASD according to the Diagnostic and Statistical Manual of the American Psychiatric Association, Fifth Edition who were aged 36 to 60 months (44 + 6.34), and nine neurotypical age-matched boys were included in the study. After detailed clinical examinations, saliva samples were collected. DNA from the samples was investigated by high-throughput sequencing of the 16S rRNA gene. The Childhood Autism Rating Scale was used to assess the severity of ASD in the case group. Results An analysis of alpha and beta diversity indexes and principal coordinate analysis revealed no significant differences between ASD and neurotypical controls nor were there significant differences in the relative abundance of the phyla and genera between the two groups. However, the distribution of operational taxonomic units (with a relative abundance> 1 %) for Bacillales, Granulicatella elegans, Micrococcaceae, Micrococcales, Neisseria zalophi, S. anginosus SK52 = DSM 2563, S. cristatus AS 1.389, S. mitis, S. oralis subsp. dentisani and S. pneumoniae were significantly higher in the ASD group (p < 0.05). Conclusions Differences in the relative abundance of some taxa in the saliva of children with ASD compared with neurotypical controls were found. Further studies are needed to understand the relationship between oral microbiota and ASD. En ligne : https://doi.org/10.1016/j.rasd.2024.102480 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Comparison of the oral microbiota of children with autism spectrum disorder in primary dentition with neurotypical controls [Texte imprimé et/ou numérique] / Gülsevim ODA, Auteur ; Deniz Ece KAYA, Auteur ; Tuba Bilbay KAYNAR, Auteur ; Emine Nursen TOPCUO?LU, Auteur ; Murat CO?KUN, Auteur ; Gamze AREN, Auteur . - 102480. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102480 Mots-clés : Autism spectrum disorder  Microbiota analysis  Saliva Index. décimale : PER Périodiques Résumé : Background The number of studies suggesting differences in oral microbiota in autism spectrum disorders (ASDs) is increasing. However, the relationship between oral microbiota and ASD has not been determined. Therefore, this study aimed to examine the oral microbiota of children with ASD compared with neurotypical controls. Method Nine boys with a diagnosis of ASD according to the Diagnostic and Statistical Manual of the American Psychiatric Association, Fifth Edition who were aged 36 to 60 months (44 + 6.34), and nine neurotypical age-matched boys were included in the study. After detailed clinical examinations, saliva samples were collected. DNA from the samples was investigated by high-throughput sequencing of the 16S rRNA gene. The Childhood Autism Rating Scale was used to assess the severity of ASD in the case group. Results An analysis of alpha and beta diversity indexes and principal coordinate analysis revealed no significant differences between ASD and neurotypical controls nor were there significant differences in the relative abundance of the phyla and genera between the two groups. However, the distribution of operational taxonomic units (with a relative abundance> 1 %) for Bacillales, Granulicatella elegans, Micrococcaceae, Micrococcales, Neisseria zalophi, S. anginosus SK52 = DSM 2563, S. cristatus AS 1.389, S. mitis, S. oralis subsp. dentisani and S. pneumoniae were significantly higher in the ASD group (p < 0.05). Conclusions Differences in the relative abundance of some taxa in the saliva of children with ASD compared with neurotypical controls were found. Further studies are needed to understand the relationship between oral microbiota and ASD. En ligne : https://doi.org/10.1016/j.rasd.2024.102480 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Atypical dynamic trust learning in individuals with high autistic traits in a multi-round trust game with multiple trustworthiness cues / Xudong ZHAO in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102481 Titre : Atypical dynamic trust learning in individuals with high autistic traits in a multi-round trust game with multiple trustworthiness cues Type de document : Texte imprimé et/ou numérique Auteurs : Xudong ZHAO, Auteur ; Wenrui LI, Auteur ; Aijia XU, Auteur ; Xintong LI, Auteur ; Wendian SHI, Auteur Article en page(s) : 102481 Langues : Anglais (eng) Mots-clés : Advice  Autism traits  Reciprocity  Reputation  Trust formation  Trust game Index. décimale : PER Périodiques Résumé : Background Understanding the trust-building process, especially in contexts requiring the integration of multiple trustworthiness cues, is a fundamental aspect of social interactions among individuals with high autistic traits (ATs). It can offer valuable insights into the social functioning of these individuals. Method Participants with high and low ATs (N = 120; 30 in each group for two experiments) completed a 10-round trust game that embedded various trustworthiness cues, including reputation, advice (Experiment 1 = direct advice; Experiment 2 = social-emotional advice), and reciprocity. Linear mixed-effects models with investment rates as the dependent variable were used to analyze the data. Results Methodologically, the experimental results elucidated the fundamental characteristics of dynamic trust formation within the context of multidimensional trust information. Furthermore, High-AT individuals showed assigned less weight to reciprocity but relied heavily on reputation, and exhibited maladaptive advice-taking. Unlike low-AT individuals, high-AT individuals did not adaptively reduce reputational effect over rounds. Conclusions Our findings highlight the unique challenges faced by individuals with high ATs when navigating complex social interactions. En ligne : https://doi.org/10.1016/j.rasd.2024.102481 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Atypical dynamic trust learning in individuals with high autistic traits in a multi-round trust game with multiple trustworthiness cues [Texte imprimé et/ou numérique] / Xudong ZHAO, Auteur ; Wenrui LI, Auteur ; Aijia XU, Auteur ; Xintong LI, Auteur ; Wendian SHI, Auteur . - 102481. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102481 Mots-clés : Advice  Autism traits  Reciprocity  Reputation  Trust formation  Trust game Index. décimale : PER Périodiques Résumé : Background Understanding the trust-building process, especially in contexts requiring the integration of multiple trustworthiness cues, is a fundamental aspect of social interactions among individuals with high autistic traits (ATs). It can offer valuable insights into the social functioning of these individuals. Method Participants with high and low ATs (N = 120; 30 in each group for two experiments) completed a 10-round trust game that embedded various trustworthiness cues, including reputation, advice (Experiment 1 = direct advice; Experiment 2 = social-emotional advice), and reciprocity. Linear mixed-effects models with investment rates as the dependent variable were used to analyze the data. Results Methodologically, the experimental results elucidated the fundamental characteristics of dynamic trust formation within the context of multidimensional trust information. Furthermore, High-AT individuals showed assigned less weight to reciprocity but relied heavily on reputation, and exhibited maladaptive advice-taking. Unlike low-AT individuals, high-AT individuals did not adaptively reduce reputational effect over rounds. Conclusions Our findings highlight the unique challenges faced by individuals with high ATs when navigating complex social interactions. En ligne : https://doi.org/10.1016/j.rasd.2024.102481 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

"Everyone should at least get a Kia": Policymaker perspectives on equity of Medicaid among transition age autistic youth / Kaitlin H. KOFFER MILLER in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102482 Titre : "Everyone should at least get a Kia": Policymaker perspectives on equity of Medicaid among transition age autistic youth Type de document : Texte imprimé et/ou numérique Auteurs : Kaitlin H. KOFFER MILLER, Auteur ; Dylan S. COOPER, Auteur ; Sha TAO, Auteur ; David S. MANDELL, Auteur ; Robert I. FIELD, Auteur ; Lindsay L. SHEA, Auteur Article en page(s) : 102482 Langues : Anglais (eng) Mots-clés : Mixed-methods  Disability  Health care financing  Health policy  Medicaid  Autism  Transition Index. décimale : PER Périodiques Résumé : Background This study examined the challenges faced by transition age autistic youth in accessing Medicaid services, considering the historical focus on children in autism research and services. The study aimed to explore Medicaid enrollment and support for this population. Method The study involved Medicaid and Protection & Advocacy (P&A) representatives from states with varying performance levels in eligibility, access, and service use. Discussions with experts focused on waivers, Early, Periodic, Screening, Detection, and Treatment (EPSDT), and barriers to service access. Results The findings highlighted the need to improve service access for transition age autistic youth. States identified the importance of maximizing EPDST utilization before aging out of childhood systems and pursuing waiver enrollment. These insights emphasized the significance of addressing service gaps during the transition to adulthood. Conclusions The study's implications for practice are substantial. Policymakers and service providers must acknowledge the limitedservice access for autistic individuals as they transition from child systems. The study emphasized the value of strategies like maximizing EPDST utilization and pursuing waivers to ensure ongoing support for autistic youth during their transition to adulthood. By addressing these challenges, practitioners can better meet the needs of transition age autistic individuals and facilitate their access to essential services. En ligne : https://doi.org/10.1016/j.rasd.2024.102482 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] "Everyone should at least get a Kia": Policymaker perspectives on equity of Medicaid among transition age autistic youth [Texte imprimé et/ou numérique] / Kaitlin H. KOFFER MILLER, Auteur ; Dylan S. COOPER, Auteur ; Sha TAO, Auteur ; David S. MANDELL, Auteur ; Robert I. FIELD, Auteur ; Lindsay L. SHEA, Auteur . - 102482. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102482 Mots-clés : Mixed-methods  Disability  Health care financing  Health policy  Medicaid  Autism  Transition Index. décimale : PER Périodiques Résumé : Background This study examined the challenges faced by transition age autistic youth in accessing Medicaid services, considering the historical focus on children in autism research and services. The study aimed to explore Medicaid enrollment and support for this population. Method The study involved Medicaid and Protection & Advocacy (P&A) representatives from states with varying performance levels in eligibility, access, and service use. Discussions with experts focused on waivers, Early, Periodic, Screening, Detection, and Treatment (EPSDT), and barriers to service access. Results The findings highlighted the need to improve service access for transition age autistic youth. States identified the importance of maximizing EPDST utilization before aging out of childhood systems and pursuing waiver enrollment. These insights emphasized the significance of addressing service gaps during the transition to adulthood. Conclusions The study's implications for practice are substantial. Policymakers and service providers must acknowledge the limitedservice access for autistic individuals as they transition from child systems. The study emphasized the value of strategies like maximizing EPDST utilization and pursuing waivers to ensure ongoing support for autistic youth during their transition to adulthood. By addressing these challenges, practitioners can better meet the needs of transition age autistic individuals and facilitate their access to essential services. En ligne : https://doi.org/10.1016/j.rasd.2024.102482 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Have information and communication technologies research for neurodevelopmental disorders improved overtime? A systematic meta-review / Carlotta BETTENCOURT in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102483 Titre : Have information and communication technologies research for neurodevelopmental disorders improved overtime? A systematic meta-review Type de document : Texte imprimé et/ou numérique Auteurs : Carlotta BETTENCOURT, Auteur ; Salvatore ANZALONE, Auteur ; Mohamed CHETOUANI, Auteur ; David COHEN, Auteur ; Charline GROSSARD, Auteur Article en page(s) : 102483 Langues : Anglais (eng) Mots-clés : Metareview  ICT  Neurodevelopmental disorders  Design  Methodology Index. décimale : PER Périodiques Résumé : Background The significant increase of Information Communication Technologies (ICTs) use for individuals with Neurodevelopmental Disorders (NDD) has created an urgent need to examine the implications of both the design and the research methodologies used to study them. Methods We searched four databases (PubMed, IEEXplore, Scopus, and ACM Digital Library) to find relevant reviews on clinical applications of ICTs with individuals with NDD. We extracted all studies (n = 1879) from 301 reviews, and classified them into categories: robots, serious games (SG), video modeling (VM), Augmentative and Alternative Communication (AAC). We randomly assessed 182 studies (45 per ICT category) stratified by years of publication using the Connolly methodology scale and design ICT inventory (DICTI). We also described the best papers per ICT (most cited or highest impact factor journals). Results Our assessments have indicated that the overall research methodology quality of ICT studies is poor. Serious Games (SG) studies have the best research methodology and ICT design quality scores. Studies on robots, Augmentative and Alternative Communication (AAC), and video modeling (VM) have shown improved research methodology over the years, though only SG design shown improvement consistently. Autism is the most prevalent NDD in terms of clinical focus in ICT therapeutic and educational interventions. Currently, no ICT has been approved as a prescription treatment in NDD, with the notable exception of EndeavorRx?, a SG for Attention Deficit Hyperactivity Disorder (ADHD). The literature also emphasizes that meeting the main research methodology criteria is essential for evidence-based medicine, Personalization, adaptability, positive feedback, human interaction and affordability are among the most important features to take into consideration in ICT design for NDD. Conclusion The review highlights the need for higher-quality studies, user-friendly technologies, personalization, positive feedback, and accessibility. ICTs are not detrimental to learning and demonstrate potential benefits for individuals with NDD. However, more evidence-based studies are needed to reach treatment prescription recommendation. En ligne : https://doi.org/10.1016/j.rasd.2024.102483 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Have information and communication technologies research for neurodevelopmental disorders improved overtime? A systematic meta-review [Texte imprimé et/ou numérique] / Carlotta BETTENCOURT, Auteur ; Salvatore ANZALONE, Auteur ; Mohamed CHETOUANI, Auteur ; David COHEN, Auteur ; Charline GROSSARD, Auteur . - 102483. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102483 Mots-clés : Metareview  ICT  Neurodevelopmental disorders  Design  Methodology Index. décimale : PER Périodiques Résumé : Background The significant increase of Information Communication Technologies (ICTs) use for individuals with Neurodevelopmental Disorders (NDD) has created an urgent need to examine the implications of both the design and the research methodologies used to study them. Methods We searched four databases (PubMed, IEEXplore, Scopus, and ACM Digital Library) to find relevant reviews on clinical applications of ICTs with individuals with NDD. We extracted all studies (n = 1879) from 301 reviews, and classified them into categories: robots, serious games (SG), video modeling (VM), Augmentative and Alternative Communication (AAC). We randomly assessed 182 studies (45 per ICT category) stratified by years of publication using the Connolly methodology scale and design ICT inventory (DICTI). We also described the best papers per ICT (most cited or highest impact factor journals). Results Our assessments have indicated that the overall research methodology quality of ICT studies is poor. Serious Games (SG) studies have the best research methodology and ICT design quality scores. Studies on robots, Augmentative and Alternative Communication (AAC), and video modeling (VM) have shown improved research methodology over the years, though only SG design shown improvement consistently. Autism is the most prevalent NDD in terms of clinical focus in ICT therapeutic and educational interventions. Currently, no ICT has been approved as a prescription treatment in NDD, with the notable exception of EndeavorRx?, a SG for Attention Deficit Hyperactivity Disorder (ADHD). The literature also emphasizes that meeting the main research methodology criteria is essential for evidence-based medicine, Personalization, adaptability, positive feedback, human interaction and affordability are among the most important features to take into consideration in ICT design for NDD. Conclusion The review highlights the need for higher-quality studies, user-friendly technologies, personalization, positive feedback, and accessibility. ICTs are not detrimental to learning and demonstrate potential benefits for individuals with NDD. However, more evidence-based studies are needed to reach treatment prescription recommendation. En ligne : https://doi.org/10.1016/j.rasd.2024.102483 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Genetic networks suggest Asperger?s syndrome as a distinct subtype of autism spectrum disorders / Sadiq NAVEED in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102484 Titre : Genetic networks suggest Asperger?s syndrome as a distinct subtype of autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Sadiq NAVEED, Auteur ; Adam A. DMYTRIW, Auteur ; Sherief GHOZY, Auteur ; Sara MORSY, Auteur Article en page(s) : 102484 Langues : Anglais (eng) Mots-clés : Asperger syndrome  Autism spectrum condition  DSM-V  WGCNA  Weighted gene correlation networks Index. décimale : PER Périodiques Résumé : Background The Diagnostic and Statistical Manual of Mental Disorders (DSM-V) issued new diagnostic criteria for autism spectrum disorders (ASD) which resulted in missing the diagnosis of some cases of Asperger?s syndrome (AS). This negatively affected the support received by those affected. In this study, we explored if AS could be biologically stratified from the broader spectrum through a gene co-expression network preservation analysis. Methods We analysed the GEO microarray data of 24 individuals with Asperger?s syndrome and 72 individuals with autism. Then, we used a weighted gene co-expression network (WGCNA) pipeline to construct gene co-expression networks. We explored whether these modules share the same co-expression patterns between autism and Asperger?s syndrome using network preservation analysis. Results Our results showed that all co-expression modules of autism are preserved into the Asperger?s syndrome. However, three modules of Asperger?s syndrome out of 30 modules were not preserved in autism. Gene enrichment analysis revealed that these modules were involved in chromatin remodelling, immune and neuroinflammatory response, synaptic and neuronal development. Brain enrichment analysis showed significant downregulation of neurodevelopment genes in different brain regions associated with impaired social recognition in Asperger?s syndrome. Conclusions The identified genetic and molecular profiles suggest that Asperger?s syndrome, despite sharing numerous similarities with autism, possesses a distinct genetic profile that makes it a distinct subtype of autism. This distinction could have significant implications for the management and treatment strategies tailored to individuals with Asperger?s syndrome. En ligne : https://doi.org/10.1016/j.rasd.2024.102484 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Genetic networks suggest Asperger?s syndrome as a distinct subtype of autism spectrum disorders [Texte imprimé et/ou numérique] / Sadiq NAVEED, Auteur ; Adam A. DMYTRIW, Auteur ; Sherief GHOZY, Auteur ; Sara MORSY, Auteur . - 102484. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102484 Mots-clés : Asperger syndrome  Autism spectrum condition  DSM-V  WGCNA  Weighted gene correlation networks Index. décimale : PER Périodiques Résumé : Background The Diagnostic and Statistical Manual of Mental Disorders (DSM-V) issued new diagnostic criteria for autism spectrum disorders (ASD) which resulted in missing the diagnosis of some cases of Asperger?s syndrome (AS). This negatively affected the support received by those affected. In this study, we explored if AS could be biologically stratified from the broader spectrum through a gene co-expression network preservation analysis. Methods We analysed the GEO microarray data of 24 individuals with Asperger?s syndrome and 72 individuals with autism. Then, we used a weighted gene co-expression network (WGCNA) pipeline to construct gene co-expression networks. We explored whether these modules share the same co-expression patterns between autism and Asperger?s syndrome using network preservation analysis. Results Our results showed that all co-expression modules of autism are preserved into the Asperger?s syndrome. However, three modules of Asperger?s syndrome out of 30 modules were not preserved in autism. Gene enrichment analysis revealed that these modules were involved in chromatin remodelling, immune and neuroinflammatory response, synaptic and neuronal development. Brain enrichment analysis showed significant downregulation of neurodevelopment genes in different brain regions associated with impaired social recognition in Asperger?s syndrome. Conclusions The identified genetic and molecular profiles suggest that Asperger?s syndrome, despite sharing numerous similarities with autism, possesses a distinct genetic profile that makes it a distinct subtype of autism. This distinction could have significant implications for the management and treatment strategies tailored to individuals with Asperger?s syndrome. En ligne : https://doi.org/10.1016/j.rasd.2024.102484 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

The impact of face masks on autistic and non-autistic adults' face processing abilities / Natasha BAXTER in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102485 Titre : The impact of face masks on autistic and non-autistic adults' face processing abilities Type de document : Texte imprimé et/ou numérique Auteurs : Natasha BAXTER, Auteur ; Lucy HARLOW, Auteur ; Ebony HARRISON, Auteur ; Caitlin SMITH, Auteur ; Hannah HOBSON, Auteur Article en page(s) : 102485 Langues : Anglais (eng) Mots-clés : Face processing  Emotion recognition  Alexithymia  Facemasks  COVID-19 Index. décimale : PER Périodiques Résumé : Atypical emotion recognition is argued to be characteristic of autism spectrum conditions (ASC), underpinned in part by atypical eye gaze, with less eye contact and more gaze direction towards the mouth. Given the widespread adoption of face masks due to the Covid-19 pandemic, exploring the effect of face masks on face processing in autism, as they occlude the mouth region, is of interest. This study investigated the impact of face masks on emotion and identity recognition, with a non-autistic (N = 50) and autistic (N = 27) sample. Participants also completed the Toronto Alexithymia Scale, and the abridged Autism Quotient, to investigate the roles of alexithymia and autistic traits in any impacts of face masks on face processing abilities. Masks were detrimental to performance for both autistic and non-autistic groups, and masks affected participants' performance on the emotion recognition task more than the identity recognition task. Autistic participants' performance was more negatively affected by the presence of masks, affecting emotion recognition precision in particular. The impact of face masks was not predicted by alexithymia or autistic traits, after gender and age were taken into account. Overall, the results suggest that masks negatively affect face processing for both non-autistic and autistic groups, particularly emotion recognition, however the impact of masks is amplified for autistic people. These results supplement autistic people?s reports that masks interfere with social interactions. En ligne : https://doi.org/10.1016/j.rasd.2024.102485 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] The impact of face masks on autistic and non-autistic adults' face processing abilities [Texte imprimé et/ou numérique] / Natasha BAXTER, Auteur ; Lucy HARLOW, Auteur ; Ebony HARRISON, Auteur ; Caitlin SMITH, Auteur ; Hannah HOBSON, Auteur . - 102485. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102485 Mots-clés : Face processing  Emotion recognition  Alexithymia  Facemasks  COVID-19 Index. décimale : PER Périodiques Résumé : Atypical emotion recognition is argued to be characteristic of autism spectrum conditions (ASC), underpinned in part by atypical eye gaze, with less eye contact and more gaze direction towards the mouth. Given the widespread adoption of face masks due to the Covid-19 pandemic, exploring the effect of face masks on face processing in autism, as they occlude the mouth region, is of interest. This study investigated the impact of face masks on emotion and identity recognition, with a non-autistic (N = 50) and autistic (N = 27) sample. Participants also completed the Toronto Alexithymia Scale, and the abridged Autism Quotient, to investigate the roles of alexithymia and autistic traits in any impacts of face masks on face processing abilities. Masks were detrimental to performance for both autistic and non-autistic groups, and masks affected participants' performance on the emotion recognition task more than the identity recognition task. Autistic participants' performance was more negatively affected by the presence of masks, affecting emotion recognition precision in particular. The impact of face masks was not predicted by alexithymia or autistic traits, after gender and age were taken into account. Overall, the results suggest that masks negatively affect face processing for both non-autistic and autistic groups, particularly emotion recognition, however the impact of masks is amplified for autistic people. These results supplement autistic people?s reports that masks interfere with social interactions. En ligne : https://doi.org/10.1016/j.rasd.2024.102485 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Cognitive and emotional empathy in neurotypical individuals with high autistic traits: The role of emotional valence / Yixin JIANG in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102486 Titre : Cognitive and emotional empathy in neurotypical individuals with high autistic traits: The role of emotional valence Type de document : Texte imprimé et/ou numérique Auteurs : Yixin JIANG, Auteur ; Shuo LIU, Auteur ; Qi CHENG, Auteur ; Yongning SONG, Auteur Article en page(s) : 102486 Langues : Anglais (eng) Mots-clés : Autistic traits  Emotional empathy  Cognitive empathy  Emotional valence Index. décimale : PER Périodiques Résumé : Background Empathy is an important ability in social interactions, and previous findings regarding empathy of high autistic traits (AT) have been mixed. Method The current study sought to investigate cognitive empathy (CE) and emotional empathy (EE) in neurotypical individuals with high AT, examining their responses to both positive and negative emotions in comparison to a matched control group within a sizable sample. Participants were 908 young Chinese adults in the neurotypical range who self-reported their AT using the Autism Quotient and Broad Autism Phenotype Questionnaire and then completed the Multifaceted Empathy Test. Results The results showed that the high AT group exhibited less CE, lower EE for positive emotions (EE-P), and intact EE for negative emotions (EE-N) compared to the low AT group. Except for EE-N, other empathic components were positively correlated with AT. The CE-P (i.e., cognitive empathy for positive emotions), CE-N (i.e., cognitive empathy for negative emotions), and EE-P showed a significantly moderate discriminatory effect in predicting AT in neurotypical adults. Conclusions Together, these results underscore that the performance on empathy of neurotypical individuals with high AT was moderated by emotional valence of stimuli. Specifically, neurotypical adults with high AT showed a general reduction in CE and a selective decrease in EE. Their EE-P was lower but EE-N was intact. En ligne : https://doi.org/10.1016/j.rasd.2024.102486 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Cognitive and emotional empathy in neurotypical individuals with high autistic traits: The role of emotional valence [Texte imprimé et/ou numérique] / Yixin JIANG, Auteur ; Shuo LIU, Auteur ; Qi CHENG, Auteur ; Yongning SONG, Auteur . - 102486. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102486 Mots-clés : Autistic traits  Emotional empathy  Cognitive empathy  Emotional valence Index. décimale : PER Périodiques Résumé : Background Empathy is an important ability in social interactions, and previous findings regarding empathy of high autistic traits (AT) have been mixed. Method The current study sought to investigate cognitive empathy (CE) and emotional empathy (EE) in neurotypical individuals with high AT, examining their responses to both positive and negative emotions in comparison to a matched control group within a sizable sample. Participants were 908 young Chinese adults in the neurotypical range who self-reported their AT using the Autism Quotient and Broad Autism Phenotype Questionnaire and then completed the Multifaceted Empathy Test. Results The results showed that the high AT group exhibited less CE, lower EE for positive emotions (EE-P), and intact EE for negative emotions (EE-N) compared to the low AT group. Except for EE-N, other empathic components were positively correlated with AT. The CE-P (i.e., cognitive empathy for positive emotions), CE-N (i.e., cognitive empathy for negative emotions), and EE-P showed a significantly moderate discriminatory effect in predicting AT in neurotypical adults. Conclusions Together, these results underscore that the performance on empathy of neurotypical individuals with high AT was moderated by emotional valence of stimuli. Specifically, neurotypical adults with high AT showed a general reduction in CE and a selective decrease in EE. Their EE-P was lower but EE-N was intact. En ligne : https://doi.org/10.1016/j.rasd.2024.102486 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Brief report: A confirmatory factor analysis of the Child Behavior Checklist in a large sample of autistic youth / Laura DE LA ROCHE in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102487 Titre : Brief report: A confirmatory factor analysis of the Child Behavior Checklist in a large sample of autistic youth Type de document : Texte imprimé et/ou numérique Auteurs : Laura DE LA ROCHE, Auteur ; Brianne DERBY, Auteur ; Molly PASCOE, Auteur ; Melissa SUSKO, Auteur ; Sabrina LUTCHMEAH, Auteur ; Jessica JONES, Auteur ; Stelios GEORGIADES, Auteur ; Rob NICOLSON, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Elizabeth KELLEY, Auteur Article en page(s) : 102487 Langues : Anglais (eng) Mots-clés : Autism  Child Behavior Checklist  Factor structure  Co-occurring conditions Index. décimale : PER Périodiques Résumé : Background Autistic youth often experience co-occurring psychiatric conditions. Checklist measures such as the Child Behavior Checklist (CBCL) can assist clinicians and researchers in assessing the symptom profiles of such conditions. Symptom profiles often overlap between autism and cooccurring psychiatric conditions (e.g., depression) in which the same symptoms occur in both. Previous research investigating the validity of the CBCL in autistic populations using factor structure has been mixed. Method Seven-hundred-and-fourteen autistic youth (293 females) aged 6-18 years (M = 11.25, SD = 3.29) participated. A confirmatory factor analysis of the 8-factor CBCL-6-18 was completed. Results Results suggest a poor model fit in autistic samples of the widely used eight-scale factor structure. Conclusions This model may not fit this sample due to the overlap of symptomatology autism has with other psychiatric condition profiles (e.g., communication and behaviors). Future research and implications, including an exploratory factor analysis on the CBCL/6-18 for autistic populations, are discussed. En ligne : https://doi.org/10.1016/j.rasd.2024.102487 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Brief report: A confirmatory factor analysis of the Child Behavior Checklist in a large sample of autistic youth [Texte imprimé et/ou numérique] / Laura DE LA ROCHE, Auteur ; Brianne DERBY, Auteur ; Molly PASCOE, Auteur ; Melissa SUSKO, Auteur ; Sabrina LUTCHMEAH, Auteur ; Jessica JONES, Auteur ; Stelios GEORGIADES, Auteur ; Rob NICOLSON, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Elizabeth KELLEY, Auteur . - 102487. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102487 Mots-clés : Autism  Child Behavior Checklist  Factor structure  Co-occurring conditions Index. décimale : PER Périodiques Résumé : Background Autistic youth often experience co-occurring psychiatric conditions. Checklist measures such as the Child Behavior Checklist (CBCL) can assist clinicians and researchers in assessing the symptom profiles of such conditions. Symptom profiles often overlap between autism and cooccurring psychiatric conditions (e.g., depression) in which the same symptoms occur in both. Previous research investigating the validity of the CBCL in autistic populations using factor structure has been mixed. Method Seven-hundred-and-fourteen autistic youth (293 females) aged 6-18 years (M = 11.25, SD = 3.29) participated. A confirmatory factor analysis of the 8-factor CBCL-6-18 was completed. Results Results suggest a poor model fit in autistic samples of the widely used eight-scale factor structure. Conclusions This model may not fit this sample due to the overlap of symptomatology autism has with other psychiatric condition profiles (e.g., communication and behaviors). Future research and implications, including an exploratory factor analysis on the CBCL/6-18 for autistic populations, are discussed. En ligne : https://doi.org/10.1016/j.rasd.2024.102487 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Parental descriptions of sensory processing in Autism / Sandra BROUCHE in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102488 Titre : Parental descriptions of sensory processing in Autism Type de document : Texte imprimé et/ou numérique Auteurs : Sandra BROUCHE, Auteur ; Natalie RIGAL, Auteur ; Fabienne CAZALIS, Auteur Article en page(s) : 102488 Langues : Anglais (eng) Mots-clés : Autism  Sensory processing  Parental descriptions  Sensory modulation  Behavioral consequences  Thematic analysis Index. décimale : PER Périodiques Résumé : Background The processing of sensory information in autistic people has a major impact on their daily lives. Current research faces challenges in fully capturing the heterogeneity of sensory profiles in autism, but caregiver perspectives could offer valuable insights, deepening our understanding of these differences in sensory experiences. The present study aimed to explore this sensory processing characterization based on the testimonies from caregivers of children and adults with autism to contribute to the knowledge obtained from answers to questionnaires. Methods Caregivers of 15 participants with autism, aged between 4 and 34 years, participated in focus group sessions. Each session was conducted using open-ended questions on sensory processing, and their responses were analyzed by means of semantic analysis using NVivo software. Results A thematic analysis of the data corpus highlighted three themes of behavioral responsivity to sensory input as reported by parents: (1) sensory input, (2) sensory modulation, and (3) impact on daily life. Sensory input encompassed seven sub-themes related to sensory channels. Sensory modulation allowed for the identification of sub-themes such as sensory overload, emotional regulation, and regulation strategies. Finally, the theme of the impact on daily life highlighted sub-themes of reactions to change, feeding problems, and risk-taking behaviors. Conclusions These findings suggest that some identified aspects, such as stimming and sensory-seeking, sensory overload and regulation strategies could potentially be added to sensory evaluations. En ligne : https://doi.org/10.1016/j.rasd.2024.102488 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Parental descriptions of sensory processing in Autism [Texte imprimé et/ou numérique] / Sandra BROUCHE, Auteur ; Natalie RIGAL, Auteur ; Fabienne CAZALIS, Auteur . - 102488. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102488 Mots-clés : Autism  Sensory processing  Parental descriptions  Sensory modulation  Behavioral consequences  Thematic analysis Index. décimale : PER Périodiques Résumé : Background The processing of sensory information in autistic people has a major impact on their daily lives. Current research faces challenges in fully capturing the heterogeneity of sensory profiles in autism, but caregiver perspectives could offer valuable insights, deepening our understanding of these differences in sensory experiences. The present study aimed to explore this sensory processing characterization based on the testimonies from caregivers of children and adults with autism to contribute to the knowledge obtained from answers to questionnaires. Methods Caregivers of 15 participants with autism, aged between 4 and 34 years, participated in focus group sessions. Each session was conducted using open-ended questions on sensory processing, and their responses were analyzed by means of semantic analysis using NVivo software. Results A thematic analysis of the data corpus highlighted three themes of behavioral responsivity to sensory input as reported by parents: (1) sensory input, (2) sensory modulation, and (3) impact on daily life. Sensory input encompassed seven sub-themes related to sensory channels. Sensory modulation allowed for the identification of sub-themes such as sensory overload, emotional regulation, and regulation strategies. Finally, the theme of the impact on daily life highlighted sub-themes of reactions to change, feeding problems, and risk-taking behaviors. Conclusions These findings suggest that some identified aspects, such as stimming and sensory-seeking, sensory overload and regulation strategies could potentially be added to sensory evaluations. En ligne : https://doi.org/10.1016/j.rasd.2024.102488 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Functional upper-extremity movements in autism: A narrative literature review / Shanan SUN in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102489 Titre : Functional upper-extremity movements in autism: A narrative literature review Type de document : Texte imprimé et/ou numérique Auteurs : Shanan SUN, Auteur ; Nicholas E. FEARS, Auteur ; Haylie L. MILLER, Auteur Article en page(s) : 102489 Langues : Anglais (eng) Mots-clés : Autism  Upper extremity  Movement  Autistic  Pointing  Handwriting  Reaching  Grasping Index. décimale : PER Périodiques Résumé : Background Many autistic individuals exhibit clinically-significant motor difficulties. Previous reviews focused on overall motor ability or coordination, but with little attention paid to quantifying differences in upper extremity skills, which are critical to many activities of daily living. Our objective was to identify and evaluate the published literature on upper extremity motor skills of autistic people. Method We conducted a literature search in PubMed, Scopus, and PsycInfo for empirical research articles reporting functional upper extremity movement performance in autism. We included articles reporting results of primary data collection from autistic people published before July 10, 2024. Articles were identified and data were extracted and evaluated using EndNote and Microsoft Excel by a team of three authors. Results Our search strategy yielded 1181 unique articles. After screening these articles, the final sample included 43 empirical research articles focused on functional upper extremity movements, including pointing (n = 13), reaching to grasp (n = 18), and handwriting (n = 12) in autism. Across these skills, autistic people exhibited slower, more variable movements than their non-autistic counterparts. Conclusions Upper extremity movement differences in autism are likely the result of differences in motor planning and increased online monitoring of movement execution. Limitations and potential bias exist in the racial, ethnic, age, and gender diversity of available data, and in the variability of methods used to assess performance. However, the current body of literature suggests significant differences between autistic and non-autistic upper extremity movements. Slower, more variable upper extremity movements likely affect many functional difficulties experienced in autistic people?s daily lives. En ligne : https://doi.org/10.1016/j.rasd.2024.102489 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Functional upper-extremity movements in autism: A narrative literature review [Texte imprimé et/ou numérique] / Shanan SUN, Auteur ; Nicholas E. FEARS, Auteur ; Haylie L. MILLER, Auteur . - 102489. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102489 Mots-clés : Autism  Upper extremity  Movement  Autistic  Pointing  Handwriting  Reaching  Grasping Index. décimale : PER Périodiques Résumé : Background Many autistic individuals exhibit clinically-significant motor difficulties. Previous reviews focused on overall motor ability or coordination, but with little attention paid to quantifying differences in upper extremity skills, which are critical to many activities of daily living. Our objective was to identify and evaluate the published literature on upper extremity motor skills of autistic people. Method We conducted a literature search in PubMed, Scopus, and PsycInfo for empirical research articles reporting functional upper extremity movement performance in autism. We included articles reporting results of primary data collection from autistic people published before July 10, 2024. Articles were identified and data were extracted and evaluated using EndNote and Microsoft Excel by a team of three authors. Results Our search strategy yielded 1181 unique articles. After screening these articles, the final sample included 43 empirical research articles focused on functional upper extremity movements, including pointing (n = 13), reaching to grasp (n = 18), and handwriting (n = 12) in autism. Across these skills, autistic people exhibited slower, more variable movements than their non-autistic counterparts. Conclusions Upper extremity movement differences in autism are likely the result of differences in motor planning and increased online monitoring of movement execution. Limitations and potential bias exist in the racial, ethnic, age, and gender diversity of available data, and in the variability of methods used to assess performance. However, the current body of literature suggests significant differences between autistic and non-autistic upper extremity movements. Slower, more variable upper extremity movements likely affect many functional difficulties experienced in autistic people?s daily lives. En ligne : https://doi.org/10.1016/j.rasd.2024.102489 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Clinical and functional characteristics of co-occurring cerebral palsy and autism spectrum disorder among children and young adults / Myriam CASSEUS in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102490 Titre : Clinical and functional characteristics of co-occurring cerebral palsy and autism spectrum disorder among children and young adults Type de document : Texte imprimé et/ou numérique Auteurs : Myriam CASSEUS, Auteur ; Hannah A. SHOVAL, Auteur ; Abby J. ERASMUS, Auteur ; JenFu CHENG, Auteur Article en page(s) : 102490 Langues : Anglais (eng) Mots-clés : Cerebral palsy  Autism spectrum disorder  Co-occurring CP+ASD  Neurodevelopmental disorders  Pediatric CP Index. décimale : PER Périodiques Résumé : Background To examine clinical and functional factors associated with co-occurring cerebral palsy (CP) and autism spectrum disorder (ASD). Methods Data were collected from the electronic health records of 994 patients with CP aged 3 to 26 years (59 % males) who received services from a U.S. hospital system between January 1, 2016 and July 1, 2021. CP, ASD, and other co-occurring conditions were abstracted using International Classification of Diseases - 10th Revision (ICD-10) codes, diagnostic summaries, and clinical descriptions. Bivariate and adjusted multivariable analyses examined the association between ASD, CP type, Gross Motor Function Classification System (GMFCS) level, speech or language disorders, and mental or behavioral problems. Results Prevalence of ASD was 8.2 % among patients with CP. Patients with GMFCS levels III-V were less likely to have a diagnosis of ASD (adjusted odds ratio [AOR] = 0.21; 95 % confidence interval [CI], 0.11-0.41). However, speech or language disorders (AOR = 6.00; 95 % CI, 2.14-16.81) and mental or behavioral problems (AOR =8.79; 95 % CI, 4.99-15.49) were associated with significantly higher odds of ASD. Conclusions Children and young adults with co-occurring CP and ASD have higher prevalence of clinical and functional impairments compared with counterparts with CP without co-occurring ASD. Screening for both conditions is necessary because of the high prevalence of ASD in this population. It is also necessary to implement specialized assessment procedures to decrease the risk of misclassifying or overlooking ASD among children and young adults with CP. En ligne : https://doi.org/10.1016/j.rasd.2024.102490 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Clinical and functional characteristics of co-occurring cerebral palsy and autism spectrum disorder among children and young adults [Texte imprimé et/ou numérique] / Myriam CASSEUS, Auteur ; Hannah A. SHOVAL, Auteur ; Abby J. ERASMUS, Auteur ; JenFu CHENG, Auteur . - 102490. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102490 Mots-clés : Cerebral palsy  Autism spectrum disorder  Co-occurring CP+ASD  Neurodevelopmental disorders  Pediatric CP Index. décimale : PER Périodiques Résumé : Background To examine clinical and functional factors associated with co-occurring cerebral palsy (CP) and autism spectrum disorder (ASD). Methods Data were collected from the electronic health records of 994 patients with CP aged 3 to 26 years (59 % males) who received services from a U.S. hospital system between January 1, 2016 and July 1, 2021. CP, ASD, and other co-occurring conditions were abstracted using International Classification of Diseases - 10th Revision (ICD-10) codes, diagnostic summaries, and clinical descriptions. Bivariate and adjusted multivariable analyses examined the association between ASD, CP type, Gross Motor Function Classification System (GMFCS) level, speech or language disorders, and mental or behavioral problems. Results Prevalence of ASD was 8.2 % among patients with CP. Patients with GMFCS levels III-V were less likely to have a diagnosis of ASD (adjusted odds ratio [AOR] = 0.21; 95 % confidence interval [CI], 0.11-0.41). However, speech or language disorders (AOR = 6.00; 95 % CI, 2.14-16.81) and mental or behavioral problems (AOR =8.79; 95 % CI, 4.99-15.49) were associated with significantly higher odds of ASD. Conclusions Children and young adults with co-occurring CP and ASD have higher prevalence of clinical and functional impairments compared with counterparts with CP without co-occurring ASD. Screening for both conditions is necessary because of the high prevalence of ASD in this population. It is also necessary to implement specialized assessment procedures to decrease the risk of misclassifying or overlooking ASD among children and young adults with CP. En ligne : https://doi.org/10.1016/j.rasd.2024.102490 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Brief report: Sensory atypicality in mothers and fathers of individuals on the autism spectrum and its relationship with emotional distress / Carmen NIETO in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102491 Titre : Brief report: Sensory atypicality in mothers and fathers of individuals on the autism spectrum and its relationship with emotional distress Type de document : Texte imprimé et/ou numérique Auteurs : Carmen NIETO, Auteur ; Helena GANDÍA-ABELLÁN, Auteur ; Ruth CAMPOS, Auteur ; Pastora MARTÍNEZ-CASTILLA, Auteur ; Beatriz CAVERO-OLIVERA, Auteur ; Margarita QUESADA-ZELJKOVIC, Auteur ; María VERDE-CAGIAO, Auteur Article en page(s) : 102491 Langues : Anglais (eng) Mots-clés : Sensory atypicality  Parents  Autism  Parental distress  Anxiety  Depression Index. décimale : PER Périodiques Résumé : Background This study investigated the prevalence of sensory atypicalities of mothers and fathers of individuals with Autism and explored the relationship between levels of emotional distress (parental distress, anxiety, and depression) and sensory processing patterns. There is limited evidence connecting these variables, and research in this area remains scarce. Method 251 parents participated in the study. 170 parents of individuals with Autism completed questionnaires on sensory experiences, parental distress, anxiety, and depression. A control group of 81 parents of individuals with typical development completed the sensory questionnaire. The relationship between sensory atypicality and emotional distress was examined only in the Autism group. Results Mothers and fathers of individuals with Autism showed a higher prevalence of sensory atypicality, especially in hyposensitive patterns. Relationships were found between specific sensory patterns and the levels of emotional distress. The hypo-reactive and hyposensitive quadrant, 'Low Registration', displayed significant predictive capacity for both anxiety and depression, while 'Sensory Sensitivity' was predominantly related to parental distress. Conclusions Awareness of specific sensory patterns could facilitate the identification of those potentially vulnerable to experiencing anxiety, depression, or parental distress. En ligne : https://doi.org/10.1016/j.rasd.2024.102491 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Brief report: Sensory atypicality in mothers and fathers of individuals on the autism spectrum and its relationship with emotional distress [Texte imprimé et/ou numérique] / Carmen NIETO, Auteur ; Helena GANDÍA-ABELLÁN, Auteur ; Ruth CAMPOS, Auteur ; Pastora MARTÍNEZ-CASTILLA, Auteur ; Beatriz CAVERO-OLIVERA, Auteur ; Margarita QUESADA-ZELJKOVIC, Auteur ; María VERDE-CAGIAO, Auteur . - 102491. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102491 Mots-clés : Sensory atypicality  Parents  Autism  Parental distress  Anxiety  Depression Index. décimale : PER Périodiques Résumé : Background This study investigated the prevalence of sensory atypicalities of mothers and fathers of individuals with Autism and explored the relationship between levels of emotional distress (parental distress, anxiety, and depression) and sensory processing patterns. There is limited evidence connecting these variables, and research in this area remains scarce. Method 251 parents participated in the study. 170 parents of individuals with Autism completed questionnaires on sensory experiences, parental distress, anxiety, and depression. A control group of 81 parents of individuals with typical development completed the sensory questionnaire. The relationship between sensory atypicality and emotional distress was examined only in the Autism group. Results Mothers and fathers of individuals with Autism showed a higher prevalence of sensory atypicality, especially in hyposensitive patterns. Relationships were found between specific sensory patterns and the levels of emotional distress. The hypo-reactive and hyposensitive quadrant, 'Low Registration', displayed significant predictive capacity for both anxiety and depression, while 'Sensory Sensitivity' was predominantly related to parental distress. Conclusions Awareness of specific sensory patterns could facilitate the identification of those potentially vulnerable to experiencing anxiety, depression, or parental distress. En ligne : https://doi.org/10.1016/j.rasd.2024.102491 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

A systematic review and meta-analysis of mental health outcomes associated with camouflaging in autistic people / Valeria KHUDIAKOVA in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102492 Titre : A systematic review and meta-analysis of mental health outcomes associated with camouflaging in autistic people Type de document : Texte imprimé et/ou numérique Auteurs : Valeria KHUDIAKOVA, Auteur ; Emmeline RUSSELL, Auteur ; Sophie SOWDEN-CARVALHO, Auteur ; Andrew D. R. SURTEES, Auteur Article en page(s) : 102492 Langues : Anglais (eng) Mots-clés : Autism  Camouflaging  Mental health  Anxiety  Depression  Wellbeing Index. décimale : PER Périodiques Résumé : Background This systematic review and meta-analysis aimed to assess the strength and quality of the evidence for the relationship between camouflaging and its potential outcomes in autistic people. With the worryingly high proportions of autistic people experiencing mental illness and suicidality, it is important to understand whether camouflaging is a risk factor in that population. Methods Searches of five databases (Web of Science, MEDLINE, PsycINFO, Embase, ProQuest Dissertations & Theses) yielded 16 studies eligible for a meta-analysis using correlations and six additional studies eligible for a narrative review, with 5897 autistic participants in total. Risk of bias was assessed for all studies using a bespoke tool. Based on the 16 studies eligible for the meta-analysis, we computed meta-correlations between camouflaging and anxiety, depression, social anxiety, and psychological wellbeing, using a random-effects model. Meta-regressions examined if study effect sizes were moderated by study quality, participants' mean age, and proportions of female and clinically diagnosed participants. Results We found significant moderate positive relationships between camouflaging and anxiety/generalised anxiety, depression, and social anxiety and a significant small negative relationship between camouflaging and mental wellbeing. There was no significant moderating effect of the aforementioned variables on study effect sizes. Discussion All of the studies were underpowered to detect small effects, and many used insufficiently validated measures. The established link between camouflaging and mental health difficulties is discussed with reference to future research and clinical practice. Longitudinal studies should also aim to establish causality. Other There was no funding associated with this review. The researchers have no conflicts of interest to disclose. The review was preregistered on PROSPERO (registration number: CRD42023473077). En ligne : https://doi.org/10.1016/j.rasd.2024.102492 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] A systematic review and meta-analysis of mental health outcomes associated with camouflaging in autistic people [Texte imprimé et/ou numérique] / Valeria KHUDIAKOVA, Auteur ; Emmeline RUSSELL, Auteur ; Sophie SOWDEN-CARVALHO, Auteur ; Andrew D. R. SURTEES, Auteur . - 102492. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102492 Mots-clés : Autism  Camouflaging  Mental health  Anxiety  Depression  Wellbeing Index. décimale : PER Périodiques Résumé : Background This systematic review and meta-analysis aimed to assess the strength and quality of the evidence for the relationship between camouflaging and its potential outcomes in autistic people. With the worryingly high proportions of autistic people experiencing mental illness and suicidality, it is important to understand whether camouflaging is a risk factor in that population. Methods Searches of five databases (Web of Science, MEDLINE, PsycINFO, Embase, ProQuest Dissertations & Theses) yielded 16 studies eligible for a meta-analysis using correlations and six additional studies eligible for a narrative review, with 5897 autistic participants in total. Risk of bias was assessed for all studies using a bespoke tool. Based on the 16 studies eligible for the meta-analysis, we computed meta-correlations between camouflaging and anxiety, depression, social anxiety, and psychological wellbeing, using a random-effects model. Meta-regressions examined if study effect sizes were moderated by study quality, participants' mean age, and proportions of female and clinically diagnosed participants. Results We found significant moderate positive relationships between camouflaging and anxiety/generalised anxiety, depression, and social anxiety and a significant small negative relationship between camouflaging and mental wellbeing. There was no significant moderating effect of the aforementioned variables on study effect sizes. Discussion All of the studies were underpowered to detect small effects, and many used insufficiently validated measures. The established link between camouflaging and mental health difficulties is discussed with reference to future research and clinical practice. Longitudinal studies should also aim to establish causality. Other There was no funding associated with this review. The researchers have no conflicts of interest to disclose. The review was preregistered on PROSPERO (registration number: CRD42023473077). En ligne : https://doi.org/10.1016/j.rasd.2024.102492 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Contrasting two types of auditory distraction in autistic and neurotypical individuals: A preregistered study / Lejla ALIKADIC in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102493 Titre : Contrasting two types of auditory distraction in autistic and neurotypical individuals: A preregistered study Type de document : Texte imprimé et/ou numérique Auteurs : Lejla ALIKADIC, Auteur ; Jan Philipp RÖER, Auteur Article en page(s) : 102493 Langues : Anglais (eng) Mots-clés : Irrelevant Sound Effect  Auditory Distraction  ASD  Autism  Working Memory  Habituation Index. décimale : PER Périodiques Résumé : Attentional control (AC) allows us to concentrate on relevant information and ignore irrelevant information. The processing of irrelevant auditory information cannot be completely suppressed, however, because of the openness of the auditory system. As a result, auditory distractors have a negative effect on a variety of different cognitive tasks. Auditory distraction in individuals with autism spectrum disorder (ASD) is of particular importance, because of differences in AC compared to neurotypical individuals. However, a systematic, adequately powered investigation has not yet been conducted. The current pre-registered study was designed to close this empirical gap using a classic and robust empirical approach. We contrasted two types of auditory distraction in adult autistic participants with at least medium intellectual and language abilities and neurotypical participants, (1) the disruptive effect of changing distractors compared to repeated distractors (i.e., the changing-state effect), and (2) the disruptive effect of a single distractor that deviates from the previous stimulus pattern (i.e., the auditory deviant effect). The weak central coherence account predicts a more pronounced changing-state effect in autistic individuals due to superior local low-level information processing, and no differences for the auditory deviant effect. The hypothesis of predictive impairment in autism predicts no differences in the changing-state effect, and a reduced auditory deviant effect due to deficits in the formation of predictions in ASD. Our results are partly consistent and partly inconsistent with these predictions. Overall, we found that autistic and neurotypical individuals are largely similar in their susceptibility to auditory distraction. En ligne : https://doi.org/10.1016/j.rasd.2024.102493 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Contrasting two types of auditory distraction in autistic and neurotypical individuals: A preregistered study [Texte imprimé et/ou numérique] / Lejla ALIKADIC, Auteur ; Jan Philipp RÖER, Auteur . - 102493. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102493 Mots-clés : Irrelevant Sound Effect  Auditory Distraction  ASD  Autism  Working Memory  Habituation Index. décimale : PER Périodiques Résumé : Attentional control (AC) allows us to concentrate on relevant information and ignore irrelevant information. The processing of irrelevant auditory information cannot be completely suppressed, however, because of the openness of the auditory system. As a result, auditory distractors have a negative effect on a variety of different cognitive tasks. Auditory distraction in individuals with autism spectrum disorder (ASD) is of particular importance, because of differences in AC compared to neurotypical individuals. However, a systematic, adequately powered investigation has not yet been conducted. The current pre-registered study was designed to close this empirical gap using a classic and robust empirical approach. We contrasted two types of auditory distraction in adult autistic participants with at least medium intellectual and language abilities and neurotypical participants, (1) the disruptive effect of changing distractors compared to repeated distractors (i.e., the changing-state effect), and (2) the disruptive effect of a single distractor that deviates from the previous stimulus pattern (i.e., the auditory deviant effect). The weak central coherence account predicts a more pronounced changing-state effect in autistic individuals due to superior local low-level information processing, and no differences for the auditory deviant effect. The hypothesis of predictive impairment in autism predicts no differences in the changing-state effect, and a reduced auditory deviant effect due to deficits in the formation of predictions in ASD. Our results are partly consistent and partly inconsistent with these predictions. Overall, we found that autistic and neurotypical individuals are largely similar in their susceptibility to auditory distraction. En ligne : https://doi.org/10.1016/j.rasd.2024.102493 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Virtual reality interview with feedback framework for situational practice of gaze among autistic adults / Saygin ARTIRAN in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102494 Titre : Virtual reality interview with feedback framework for situational practice of gaze among autistic adults Type de document : Texte imprimé et/ou numérique Auteurs : Saygin ARTIRAN, Auteur ; Shana COHEN, Auteur ; Pamela COSMAN, Auteur Article en page(s) : 102494 Langues : Anglais (eng) Mots-clés : Gaze behavior  Job interview practice  Social interaction practice  Autism spectrum  Virtual reality  Social modulation Index. décimale : PER Périodiques Résumé : Background Autistic individuals commonly seek employment; however, only a small fraction are in the workforce. In part, this might be due to mismatches between their social patterns of attention and gaze, and society?s normative expectations during interviews. Method To help mitigate such disadvantages through a solo situational practice tool, we present a framework that consists of a virtual reality (VR) based job interview simulation and a coaching component. Employing data visualization, video modeling, and VR role-play of the targeted behavior, the coaching support could be done in a self-deliverable practice manner. A participatory design session with two autistic design partners was important in the co-creation of the feedback methods, making them easier to understand, and including positive reinforcement. Results Fourteen autistic individuals used the VR job interview simulation tool. Eleven received the gaze analysis and support stage and participated in a second VR simulation session. Preliminary results were positive, in that participant scores on average eye contact duration, average time without eye contact, and percentage of eye contact while listening and while speaking generally approached the corresponding medians of the non-autistic reference dataset. Participants were surveyed about the utility of the tool after the second feedback session and two months later. All survey respondents perceived the tool to be useful and the provided feedback to be helpful in daily social interactions. Conclusions This study provides insights towards the development of a VR job interview simulation and feedback framework that can enable solo situational practice of gaze and common interview questions. En ligne : https://doi.org/10.1016/j.rasd.2024.102494 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Virtual reality interview with feedback framework for situational practice of gaze among autistic adults [Texte imprimé et/ou numérique] / Saygin ARTIRAN, Auteur ; Shana COHEN, Auteur ; Pamela COSMAN, Auteur . - 102494. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102494 Mots-clés : Gaze behavior  Job interview practice  Social interaction practice  Autism spectrum  Virtual reality  Social modulation Index. décimale : PER Périodiques Résumé : Background Autistic individuals commonly seek employment; however, only a small fraction are in the workforce. In part, this might be due to mismatches between their social patterns of attention and gaze, and society?s normative expectations during interviews. Method To help mitigate such disadvantages through a solo situational practice tool, we present a framework that consists of a virtual reality (VR) based job interview simulation and a coaching component. Employing data visualization, video modeling, and VR role-play of the targeted behavior, the coaching support could be done in a self-deliverable practice manner. A participatory design session with two autistic design partners was important in the co-creation of the feedback methods, making them easier to understand, and including positive reinforcement. Results Fourteen autistic individuals used the VR job interview simulation tool. Eleven received the gaze analysis and support stage and participated in a second VR simulation session. Preliminary results were positive, in that participant scores on average eye contact duration, average time without eye contact, and percentage of eye contact while listening and while speaking generally approached the corresponding medians of the non-autistic reference dataset. Participants were surveyed about the utility of the tool after the second feedback session and two months later. All survey respondents perceived the tool to be useful and the provided feedback to be helpful in daily social interactions. Conclusions This study provides insights towards the development of a VR job interview simulation and feedback framework that can enable solo situational practice of gaze and common interview questions. En ligne : https://doi.org/10.1016/j.rasd.2024.102494 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

An acceptability and feasibility investigation of a community-based motor program for autistic children with moderate and high support needs / Lee SVENSSON in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102495 Titre : An acceptability and feasibility investigation of a community-based motor program for autistic children with moderate and high support needs Type de document : Texte imprimé et/ou numérique Auteurs : Lee SVENSSON, Auteur ; Michalis STYLIANOU, Auteur ; Jessica HILL, Auteur ; Stewart G. TROST, Auteur ; John CAIRNEY, Auteur Article en page(s) : 102495 Langues : Anglais (eng) Mots-clés : Fundamental movement skills  Therapy  Autism  Exploratory Index. décimale : PER Périodiques Résumé : Background General motor impairments are ubiquitous in Autism and are positively correlated with autism symptom severity. This study assessed the feasibility and acceptability of a 13-week community-based motor program for autistic children with moderate and high support needs (MHS). Method In this exploratory single arm within-subject study, 10 autistic children with MHS, ages 4-10 years, completed a community-based motor program delivered in a one-on-one format by therapists. Feasibility was determined through recruitment, retention, attendance, enjoyment, engagement and useability of motor, physical activity (PA), and behavioural assessment tools. Thematic analysis evaluated post-intervention semi-structured parent interviews. Results High program attendance and retention were demonstrated, and therapists reported child engagement and enjoyment were high. Identified themes revealed parents perceived unexpected substantial positive impacts including improvements in social, motor, and behavioural outcomes. They highly valued both the program and the therapeutic relationships fostered within it. Although parents of the children with the higher support needs reported the most substantial improvements, these children were unable to score on motor assessments due to difficulties following instructions and off-task behaviours. Additionally, only four participants wore an accelerometer-based PA monitor. Conclusions This community-based motor program was considered feasible and acceptable by the children?s parents, and qualitative findings provided valuable insights into clinical practice for children with MHS. However, recruitment challenges and assessment tools being unfeasible for children with higher support needs led to low participant numbers. Future evaluations should explore alternative assessment measures and study designs, given the challenges associated with studying such a heterogenous and complex group. En ligne : https://doi.org/10.1016/j.rasd.2024.102495 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] An acceptability and feasibility investigation of a community-based motor program for autistic children with moderate and high support needs [Texte imprimé et/ou numérique] / Lee SVENSSON, Auteur ; Michalis STYLIANOU, Auteur ; Jessica HILL, Auteur ; Stewart G. TROST, Auteur ; John CAIRNEY, Auteur . - 102495. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102495 Mots-clés : Fundamental movement skills  Therapy  Autism  Exploratory Index. décimale : PER Périodiques Résumé : Background General motor impairments are ubiquitous in Autism and are positively correlated with autism symptom severity. This study assessed the feasibility and acceptability of a 13-week community-based motor program for autistic children with moderate and high support needs (MHS). Method In this exploratory single arm within-subject study, 10 autistic children with MHS, ages 4-10 years, completed a community-based motor program delivered in a one-on-one format by therapists. Feasibility was determined through recruitment, retention, attendance, enjoyment, engagement and useability of motor, physical activity (PA), and behavioural assessment tools. Thematic analysis evaluated post-intervention semi-structured parent interviews. Results High program attendance and retention were demonstrated, and therapists reported child engagement and enjoyment were high. Identified themes revealed parents perceived unexpected substantial positive impacts including improvements in social, motor, and behavioural outcomes. They highly valued both the program and the therapeutic relationships fostered within it. Although parents of the children with the higher support needs reported the most substantial improvements, these children were unable to score on motor assessments due to difficulties following instructions and off-task behaviours. Additionally, only four participants wore an accelerometer-based PA monitor. Conclusions This community-based motor program was considered feasible and acceptable by the children?s parents, and qualitative findings provided valuable insights into clinical practice for children with MHS. However, recruitment challenges and assessment tools being unfeasible for children with higher support needs led to low participant numbers. Future evaluations should explore alternative assessment measures and study designs, given the challenges associated with studying such a heterogenous and complex group. En ligne : https://doi.org/10.1016/j.rasd.2024.102495 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Mapping the global research on feeding and eating disorders and autism spectrum disorder (2014-2023): A bibliometric and network analysis / Fabio Batista MOTA in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102497 Titre : Mapping the global research on feeding and eating disorders and autism spectrum disorder (2014-2023): A bibliometric and network analysis Type de document : Texte imprimé et/ou numérique Auteurs : Fabio Batista MOTA, Auteur ; Anatália Leal JATOBÁ NETA, Auteur ; Bernardo Pereira CABRAL, Auteur Article en page(s) : 102497 Langues : Anglais (eng) Mots-clés : Feeding and eating disorders  Autism spectrum disorder  Scientific publications  PRISMA  Bibliometrics  Network analysis Index. décimale : PER Périodiques Résumé : Objective This study maps the global research landscape on feeding and eating disorders (FEDs) and autism spectrum disorder (ASD). Method We used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), bibliometrics, and network analyses to assess 199 peer-reviewed articles from the Web of Science Core Collection, published between 2014 and 2023. Results The results show an annual publication increase, especially in the last three years. The Journal of Autism and Developmental Disorders and the European Eating Disorders Review were the main publishers. Anorexia Nervosa, Avoidant Restrictive Food Intake Disorder, food selectivity, mealtime behaviors, parents, children, and females are among the most cited keywords. The main Research Areas were Psychology and Psychiatry, and Pediatrics and Psychology were the most central nodes of the network. The United Kingdom and the United States of America lead in publications and are the most central nodes in the network. King?s College London (KCL) and South London & Maudsley NHS Foundation Trust lead the ranking of organizations, with KCL as the most central node in the network. Conclusions Our study indicates a growing interest in research related to FEDs and ASD. The global landscape of research produced over the last ten years offers insights for future studies and interinstitutional collaborations. En ligne : https://doi.org/10.1016/j.rasd.2024.102497 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Mapping the global research on feeding and eating disorders and autism spectrum disorder (2014-2023): A bibliometric and network analysis [Texte imprimé et/ou numérique] / Fabio Batista MOTA, Auteur ; Anatália Leal JATOBÁ NETA, Auteur ; Bernardo Pereira CABRAL, Auteur . - 102497. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102497 Mots-clés : Feeding and eating disorders  Autism spectrum disorder  Scientific publications  PRISMA  Bibliometrics  Network analysis Index. décimale : PER Périodiques Résumé : Objective This study maps the global research landscape on feeding and eating disorders (FEDs) and autism spectrum disorder (ASD). Method We used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), bibliometrics, and network analyses to assess 199 peer-reviewed articles from the Web of Science Core Collection, published between 2014 and 2023. Results The results show an annual publication increase, especially in the last three years. The Journal of Autism and Developmental Disorders and the European Eating Disorders Review were the main publishers. Anorexia Nervosa, Avoidant Restrictive Food Intake Disorder, food selectivity, mealtime behaviors, parents, children, and females are among the most cited keywords. The main Research Areas were Psychology and Psychiatry, and Pediatrics and Psychology were the most central nodes of the network. The United Kingdom and the United States of America lead in publications and are the most central nodes in the network. King?s College London (KCL) and South London & Maudsley NHS Foundation Trust lead the ranking of organizations, with KCL as the most central node in the network. Conclusions Our study indicates a growing interest in research related to FEDs and ASD. The global landscape of research produced over the last ten years offers insights for future studies and interinstitutional collaborations. En ligne : https://doi.org/10.1016/j.rasd.2024.102497 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Event-, time- and activity-based prospective memory in children with higher autistic traits / Xiao-min SU in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102498 Titre : Event-, time- and activity-based prospective memory in children with higher autistic traits Type de document : Texte imprimé et/ou numérique Auteurs : Xiao-min SU, Auteur ; Tian-Xiao YANG, Auteur ; Sascha ZUBER, Auteur ; Shuai-biao LI, Auteur ; Rong-Man YUAN, Auteur ; Chen-wei YUAN, Auteur ; Han-Xue YANG, Auteur ; Ya WANG, Auteur ; Raymond C. K. CHAN, Auteur Article en page(s) : 102498 Langues : Anglais (eng) Mots-clés : Prospective memory  Autistic traits  Working memory  Inhibition Index. décimale : PER Périodiques Résumé : Background School-age children rely on prospective memory (PM) to complete various tasks in the future. Previous research suggests children with autism spectrum disorders exhibit PM impairment, but whether PM impairment extends to children with higher autistic traits remains unclear. In the present study, we aimed to compare PM performance in children with higher and lower autistic traits and to examine potentially differential associations to executive functions. Method Forty pairs of children with higher and lower autistic traits between age 6- to 12-years old completed event-, time-, and activity-based PM tasks, and two executive function tasks (i.e., inhibition and working memory). We also collected parents-rated PM abilities using the Prospective and Retrospective Memory Questionnaire for Children. Results The two groups showed similar performance in both executive function tasks, the 3?PM tasks and parents-reported PM in daily life. In children with lower autistic traits, performance of the time-based PM task was correlated with working memory whereas it was correlated with inhibition function in children with higher autistic traits. Moreover, children with higher autistic traits exhibited a continuous reduction of time monitoring behavior across trials, leading to worse performance in the last PM trial compared with children with lower autistic traits. Conclusion Children with higher autistic traits showed intact executive functioning and similar PM performance as children with lower autistic traits, but they relied on different types of executive functions to complete time-based PM tasks. Moreover, children with higher autistic traits showed reduced time monitoring behavior and unstable PM performance across time. En ligne : https://doi.org/10.1016/j.rasd.2024.102498 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Event-, time- and activity-based prospective memory in children with higher autistic traits [Texte imprimé et/ou numérique] / Xiao-min SU, Auteur ; Tian-Xiao YANG, Auteur ; Sascha ZUBER, Auteur ; Shuai-biao LI, Auteur ; Rong-Man YUAN, Auteur ; Chen-wei YUAN, Auteur ; Han-Xue YANG, Auteur ; Ya WANG, Auteur ; Raymond C. K. CHAN, Auteur . - 102498. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102498 Mots-clés : Prospective memory  Autistic traits  Working memory  Inhibition Index. décimale : PER Périodiques Résumé : Background School-age children rely on prospective memory (PM) to complete various tasks in the future. Previous research suggests children with autism spectrum disorders exhibit PM impairment, but whether PM impairment extends to children with higher autistic traits remains unclear. In the present study, we aimed to compare PM performance in children with higher and lower autistic traits and to examine potentially differential associations to executive functions. Method Forty pairs of children with higher and lower autistic traits between age 6- to 12-years old completed event-, time-, and activity-based PM tasks, and two executive function tasks (i.e., inhibition and working memory). We also collected parents-rated PM abilities using the Prospective and Retrospective Memory Questionnaire for Children. Results The two groups showed similar performance in both executive function tasks, the 3?PM tasks and parents-reported PM in daily life. In children with lower autistic traits, performance of the time-based PM task was correlated with working memory whereas it was correlated with inhibition function in children with higher autistic traits. Moreover, children with higher autistic traits exhibited a continuous reduction of time monitoring behavior across trials, leading to worse performance in the last PM trial compared with children with lower autistic traits. Conclusion Children with higher autistic traits showed intact executive functioning and similar PM performance as children with lower autistic traits, but they relied on different types of executive functions to complete time-based PM tasks. Moreover, children with higher autistic traits showed reduced time monitoring behavior and unstable PM performance across time. En ligne : https://doi.org/10.1016/j.rasd.2024.102498 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Chronic administration of low dose aspirin alleviates ASD-like behaviors and activates AMPK in valproic acid-exposed rats / Yueting ZHANG in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102499 Titre : Chronic administration of low dose aspirin alleviates ASD-like behaviors and activates AMPK in valproic acid-exposed rats Type de document : Texte imprimé et/ou numérique Auteurs : Yueting ZHANG, Auteur ; Liyan QIN, Auteur ; Xufang DAI, Auteur Article en page(s) : 102499 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Aspirin  Valproic acid  AMPK Index. décimale : PER Périodiques Résumé : Background Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder distinguished by deficits in social communication and the presence of restricted/repetitive behaviors. There has been a global increase in the prevalence of ASD, yet the underlying causes of ASD remain inadequately understood, and there is currently no pharmacological intervention for the core symptoms of ASD. However, recent studies have suggested that aspirin may have the potential for use in the treatment of ASD. Method Pregnant rats were administered either VPA or normal saline on gestational day 12.5. The male pups were administered a low dose of aspirin (1?mg/kg) or a vehicle control daily from postnatal day 23 to day 52. ASD-like behaviors were assessed by social interaction, spontaneous grooming test, open field test and light-dark transitions. The activity of AMP-activated protein kinase (AMPK) was quantified by measuring the level of p-AMPK using an immunoblotting assay. Results Chronic administration of low dose aspirin resulted in significant improvements in social approach deficits, a reduction in repetitive grooming, and the alleviation of anxiety-like behavior in ASD rats. Furthermore, aspirin administration also led to the activation of AMPK in the hippocampus of rats exposed to VPA. Conclusions These results raise the question of the need for further investigation of agents with mechanisms related to aspirin in ASD. En ligne : https://doi.org/10.1016/j.rasd.2024.102499 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Chronic administration of low dose aspirin alleviates ASD-like behaviors and activates AMPK in valproic acid-exposed rats [Texte imprimé et/ou numérique] / Yueting ZHANG, Auteur ; Liyan QIN, Auteur ; Xufang DAI, Auteur . - 102499. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102499 Mots-clés : Autism spectrum disorder  Aspirin  Valproic acid  AMPK Index. décimale : PER Périodiques Résumé : Background Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder distinguished by deficits in social communication and the presence of restricted/repetitive behaviors. There has been a global increase in the prevalence of ASD, yet the underlying causes of ASD remain inadequately understood, and there is currently no pharmacological intervention for the core symptoms of ASD. However, recent studies have suggested that aspirin may have the potential for use in the treatment of ASD. Method Pregnant rats were administered either VPA or normal saline on gestational day 12.5. The male pups were administered a low dose of aspirin (1?mg/kg) or a vehicle control daily from postnatal day 23 to day 52. ASD-like behaviors were assessed by social interaction, spontaneous grooming test, open field test and light-dark transitions. The activity of AMP-activated protein kinase (AMPK) was quantified by measuring the level of p-AMPK using an immunoblotting assay. Results Chronic administration of low dose aspirin resulted in significant improvements in social approach deficits, a reduction in repetitive grooming, and the alleviation of anxiety-like behavior in ASD rats. Furthermore, aspirin administration also led to the activation of AMPK in the hippocampus of rats exposed to VPA. Conclusions These results raise the question of the need for further investigation of agents with mechanisms related to aspirin in ASD. En ligne : https://doi.org/10.1016/j.rasd.2024.102499 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540