Dépouillements

Editorial: Considering Transient Instantiators / Jed T. ELISON in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1173-1174 Titre : Editorial: Considering Transient Instantiators Type de document : Texte imprimé et/ou numérique Auteurs : Jed T. ELISON, Auteur Article en page(s) : p.1173-1174 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1017/s0954579420001807 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Editorial: Considering Transient Instantiators [Texte imprimé et/ou numérique] / Jed T. ELISON, Auteur . - p.1173-1174. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1173-1174 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1017/s0954579420001807 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Affording autism an early brain development re-definition / Ami KLIN in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1175-1189 Titre : Affording autism an early brain development re-definition Type de document : Texte imprimé et/ou numérique Auteurs : Ami KLIN, Auteur ; Megan MICHELETTI, Auteur ; Cheryl KLAIMAN, Auteur ; Sarah SHULTZ, Auteur ; John N. CONSTANTINO, Auteur ; Warren JONES, Auteur Article en page(s) : p.1175-1189 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  brain development  definition  early diagnosis  early intervention Index. décimale : PER Périodiques Résumé : The national priority to advance early detection and intervention for children with autism spectrum disorder (ASD) has not reduced the late age of ASD diagnosis in the US over several consecutive Centers for Disease Control and Prevention (CDC) surveillance cohorts, with traditionally under-served populations accessing diagnosis later still. In this review, we explore a potential perceptual barrier to this enterprise which views ASD in terms that are contradicted by current science, and which may have its origins in the current definition of the condition and in its historical associations. To address this perceptual barrier, we propose a re-definition of ASD in early brain development terms, with a view to revisit the world of opportunities afforded by current science to optimize children's outcomes despite the risks that they are born with. This view is presented here to counter outdated notions that potentially devastating disability is determined the moment a child is born, and that these burdens are inevitable, with opportunities for improvement being constrained to only alleviation of symptoms or limited improvements in adaptive skills. The impetus for this piece is the concern that such views of complex neurodevelopmental conditions, such as ASD, can become self-fulfilling science and policy, in ways that are diametrically opposed to what we currently know, and are learning every day, of how genetic risk becomes, or not, instantiated as lifetime disabilities. En ligne : http://dx.doi.org/10.1017/s0954579420000802 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Affording autism an early brain development re-definition [Texte imprimé et/ou numérique] / Ami KLIN, Auteur ; Megan MICHELETTI, Auteur ; Cheryl KLAIMAN, Auteur ; Sarah SHULTZ, Auteur ; John N. CONSTANTINO, Auteur ; Warren JONES, Auteur . - p.1175-1189. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1175-1189 Mots-clés : autism spectrum disorder  brain development  definition  early diagnosis  early intervention Index. décimale : PER Périodiques Résumé : The national priority to advance early detection and intervention for children with autism spectrum disorder (ASD) has not reduced the late age of ASD diagnosis in the US over several consecutive Centers for Disease Control and Prevention (CDC) surveillance cohorts, with traditionally under-served populations accessing diagnosis later still. In this review, we explore a potential perceptual barrier to this enterprise which views ASD in terms that are contradicted by current science, and which may have its origins in the current definition of the condition and in its historical associations. To address this perceptual barrier, we propose a re-definition of ASD in early brain development terms, with a view to revisit the world of opportunities afforded by current science to optimize children's outcomes despite the risks that they are born with. This view is presented here to counter outdated notions that potentially devastating disability is determined the moment a child is born, and that these burdens are inevitable, with opportunities for improvement being constrained to only alleviation of symptoms or limited improvements in adaptive skills. The impetus for this piece is the concern that such views of complex neurodevelopmental conditions, such as ASD, can become self-fulfilling science and policy, in ways that are diametrically opposed to what we currently know, and are learning every day, of how genetic risk becomes, or not, instantiated as lifetime disabilities. En ligne : http://dx.doi.org/10.1017/s0954579420000802 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Genetic architecture of reciprocal social behavior in toddlers: Implications for heterogeneity in the early origins of autism spectrum disorder / Natasha MARRUS in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1190-1205 Titre : Genetic architecture of reciprocal social behavior in toddlers: Implications for heterogeneity in the early origins of autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Natasha MARRUS, Auteur ; Julia D. GRANT, Auteur ; Brooke HARRIS-OLENAK, Auteur ; Jordan ALBRIGHT, Auteur ; Drew BOLSTER, Auteur ; Jon Randolph HABER, Auteur ; Theodore JACOB, Auteur ; Yi ZHANG, Auteur ; Andrew C. HEATH, Auteur ; Arpana AGRAWAL, Auteur ; John N. CONSTANTINO, Auteur ; Jed T. ELISON, Auteur ; Anne L. GLOWINSKI, Auteur Article en page(s) : p.1190-1205 Langues : Anglais (eng) Mots-clés : quantitative autistic traits  reciprocal social behavior  toddlers  twins  vrRSB Index. décimale : PER Périodiques Résumé : Impairment in reciprocal social behavior (RSB), an essential component of early social competence, clinically defines autism spectrum disorder (ASD). However, the behavioral and genetic architecture of RSB in toddlerhood, when ASD first emerges, has not been fully characterized. We analyzed data from a quantitative video-referenced rating of RSB (vrRSB) in two toddler samples: a community-based volunteer research registry (n = 1,563) and an ethnically diverse, longitudinal twin sample ascertained from two state birth registries (n = 714). Variation in RSB was continuously distributed, temporally stable, significantly associated with ASD risk at age 18 months, and only modestly explained by sociodemographic and medical factors (r2 = 9.4%). Five latent RSB factors were identified and corresponded to aspects of social communication or restricted repetitive behaviors, the two core ASD symptom domains. Quantitative genetic analyses indicated substantial heritability for all factors at age 24 months (h2 ? .61). Genetic influences strongly overlapped across all factors, with a social motivation factor showing evidence of newly-emerging genetic influences between the ages of 18 and 24 months. RSB constitutes a heritable, trait-like competency whose factorial and genetic structure is generalized across diverse populations, demonstrating its role as an early, enduring dimension of inherited variation in human social behavior. Substantially overlapping RSB domains, measurable when core ASD features arise and consolidate, may serve as markers of specific pathways to autism and anchors to inform determinants of autism's heterogeneity. En ligne : http://dx.doi.org/10.1017/s0954579420000723 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Genetic architecture of reciprocal social behavior in toddlers: Implications for heterogeneity in the early origins of autism spectrum disorder [Texte imprimé et/ou numérique] / Natasha MARRUS, Auteur ; Julia D. GRANT, Auteur ; Brooke HARRIS-OLENAK, Auteur ; Jordan ALBRIGHT, Auteur ; Drew BOLSTER, Auteur ; Jon Randolph HABER, Auteur ; Theodore JACOB, Auteur ; Yi ZHANG, Auteur ; Andrew C. HEATH, Auteur ; Arpana AGRAWAL, Auteur ; John N. CONSTANTINO, Auteur ; Jed T. ELISON, Auteur ; Anne L. GLOWINSKI, Auteur . - p.1190-1205. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1190-1205 Mots-clés : quantitative autistic traits  reciprocal social behavior  toddlers  twins  vrRSB Index. décimale : PER Périodiques Résumé : Impairment in reciprocal social behavior (RSB), an essential component of early social competence, clinically defines autism spectrum disorder (ASD). However, the behavioral and genetic architecture of RSB in toddlerhood, when ASD first emerges, has not been fully characterized. We analyzed data from a quantitative video-referenced rating of RSB (vrRSB) in two toddler samples: a community-based volunteer research registry (n = 1,563) and an ethnically diverse, longitudinal twin sample ascertained from two state birth registries (n = 714). Variation in RSB was continuously distributed, temporally stable, significantly associated with ASD risk at age 18 months, and only modestly explained by sociodemographic and medical factors (r2 = 9.4%). Five latent RSB factors were identified and corresponded to aspects of social communication or restricted repetitive behaviors, the two core ASD symptom domains. Quantitative genetic analyses indicated substantial heritability for all factors at age 24 months (h2 ? .61). Genetic influences strongly overlapped across all factors, with a social motivation factor showing evidence of newly-emerging genetic influences between the ages of 18 and 24 months. RSB constitutes a heritable, trait-like competency whose factorial and genetic structure is generalized across diverse populations, demonstrating its role as an early, enduring dimension of inherited variation in human social behavior. Substantially overlapping RSB domains, measurable when core ASD features arise and consolidate, may serve as markers of specific pathways to autism and anchors to inform determinants of autism's heterogeneity. En ligne : http://dx.doi.org/10.1017/s0954579420000723 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

The association between social emotional development and symptom presentation in autism spectrum disorder / Kyle B. REID in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1206-1216 Titre : The association between social emotional development and symptom presentation in autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Kyle B. REID, Auteur ; Lori-Ann R. SACREY, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Sarah RAZA, Auteur ; Jessica BRIAN, Auteur ; Isabel M SMITH, Auteur ; Susan E. BRYSON, Auteur ; Vickie ARMSTRONG, Auteur ; Wendy ROBERTS, Auteur ; Peter SZATMARI, Auteur ; Tracy VAILLANCOURT, Auteur ; Caroline RONCADIN, Auteur Article en page(s) : p.1206-1216 Langues : Anglais (eng) Mots-clés : Bitsea  Itsea  autism spectrum disorder  high-risk cohort  infant sibling Index. décimale : PER Périodiques Résumé : Understanding differences in social-emotional behavior can help identify atypical development. This study examined the differences in social-emotional development in children at increased risk of an autism spectrum disorder (ASD) diagnosis (infant siblings of children diagnosed with the disorder). Parents completed the Brief Infant-Toddler Social-Emotional Assessment (BITSEA) to determine its ability to flag children with later-diagnosed ASD in a high-risk (HR) sibling population. Parents of HR (n = 311) and low-risk (LR; no family history of ASD; n = 127) children completed the BITSEA when their children were 18 months old and all children underwent a diagnostic assessment for ASD at age 3 years. All six subscales of the BITSEA (Problems, Competence, ASD Problems, ASD Competence, Total ASD Score, and Red Flags) distinguished between those in the HR group who were diagnosed with ASD (n = 84) compared to non-ASD-diagnosed children (both HR-N and LR). One subscale (BITSEA Competence) differentiated between the HR children not diagnosed with ASD and the LR group. The results suggest that tracking early social-emotional development may have implications for all HR children, as they are at increased risk of ASD but also other developmental or mental health conditions. En ligne : http://dx.doi.org/10.1017/s0954579420000711 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] The association between social emotional development and symptom presentation in autism spectrum disorder [Texte imprimé et/ou numérique] / Kyle B. REID, Auteur ; Lori-Ann R. SACREY, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Sarah RAZA, Auteur ; Jessica BRIAN, Auteur ; Isabel M SMITH, Auteur ; Susan E. BRYSON, Auteur ; Vickie ARMSTRONG, Auteur ; Wendy ROBERTS, Auteur ; Peter SZATMARI, Auteur ; Tracy VAILLANCOURT, Auteur ; Caroline RONCADIN, Auteur . - p.1206-1216. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1206-1216 Mots-clés : Bitsea  Itsea  autism spectrum disorder  high-risk cohort  infant sibling Index. décimale : PER Périodiques Résumé : Understanding differences in social-emotional behavior can help identify atypical development. This study examined the differences in social-emotional development in children at increased risk of an autism spectrum disorder (ASD) diagnosis (infant siblings of children diagnosed with the disorder). Parents completed the Brief Infant-Toddler Social-Emotional Assessment (BITSEA) to determine its ability to flag children with later-diagnosed ASD in a high-risk (HR) sibling population. Parents of HR (n = 311) and low-risk (LR; no family history of ASD; n = 127) children completed the BITSEA when their children were 18 months old and all children underwent a diagnostic assessment for ASD at age 3 years. All six subscales of the BITSEA (Problems, Competence, ASD Problems, ASD Competence, Total ASD Score, and Red Flags) distinguished between those in the HR group who were diagnosed with ASD (n = 84) compared to non-ASD-diagnosed children (both HR-N and LR). One subscale (BITSEA Competence) differentiated between the HR children not diagnosed with ASD and the LR group. The results suggest that tracking early social-emotional development may have implications for all HR children, as they are at increased risk of ASD but also other developmental or mental health conditions. En ligne : http://dx.doi.org/10.1017/s0954579420000711 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Early behavioral profiles elucidating vulnerability and resiliency to later ASD outcomes / Rebecca J. LANDA in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1217-1229 Titre : Early behavioral profiles elucidating vulnerability and resiliency to later ASD outcomes Type de document : Texte imprimé et/ou numérique Auteurs : Rebecca J. LANDA, Auteur ; Rachel REETZKE, Auteur ; Madiha TAHSEEN, Auteur ; Christine Reiner HESS, Auteur Article en page(s) : p.1217-1229 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  high-risk siblings  resilience  symptomology  vulnerability Index. décimale : PER Périodiques Résumé : Infant siblings of children with autism spectrum disorder (ASD) exhibit greater heterogeneity in behavioral presentation and outcomes relative to infants at low familial risk (LR), yet there is limited understanding of the diverse developmental profiles that characterize these infants. We applied a hierarchical agglomerative cluster analysis approach to parse developmental heterogeneity in 420 toddlers with heightened (HR) and low (LR) familial risk for ASD using measures of four dimensions of development: language, social, play, and restricted and repetitive behaviors (RRB). Results revealed a two-cluster solution. Comparisons of clusters revealed significantly lower language, social, and play performance, and higher levels of restricted and repetitive behaviors in Cluster 1 relative to Cluster 2. In Cluster 1, 25% of children were later diagnosed with ASD compared to 8% in Cluster 2. Comparisons within Cluster 1 between subgroups of toddlers having ASD+ versus ASD- 36-month outcomes revealed significantly lower functioning in the ASD+ subgroup across cognitive, motor, social, language, symbolic, and speech dimensions. Findings suggest profiles of early development associated with resiliency and vulnerability to later ASD diagnosis, with multidimensional developmental lags signaling vulnerability to ASD diagnosis. En ligne : http://dx.doi.org/10.1017/s0954579420000814 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Early behavioral profiles elucidating vulnerability and resiliency to later ASD outcomes [Texte imprimé et/ou numérique] / Rebecca J. LANDA, Auteur ; Rachel REETZKE, Auteur ; Madiha TAHSEEN, Auteur ; Christine Reiner HESS, Auteur . - p.1217-1229. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1217-1229 Mots-clés : autism spectrum disorder  high-risk siblings  resilience  symptomology  vulnerability Index. décimale : PER Périodiques Résumé : Infant siblings of children with autism spectrum disorder (ASD) exhibit greater heterogeneity in behavioral presentation and outcomes relative to infants at low familial risk (LR), yet there is limited understanding of the diverse developmental profiles that characterize these infants. We applied a hierarchical agglomerative cluster analysis approach to parse developmental heterogeneity in 420 toddlers with heightened (HR) and low (LR) familial risk for ASD using measures of four dimensions of development: language, social, play, and restricted and repetitive behaviors (RRB). Results revealed a two-cluster solution. Comparisons of clusters revealed significantly lower language, social, and play performance, and higher levels of restricted and repetitive behaviors in Cluster 1 relative to Cluster 2. In Cluster 1, 25% of children were later diagnosed with ASD compared to 8% in Cluster 2. Comparisons within Cluster 1 between subgroups of toddlers having ASD+ versus ASD- 36-month outcomes revealed significantly lower functioning in the ASD+ subgroup across cognitive, motor, social, language, symbolic, and speech dimensions. Findings suggest profiles of early development associated with resiliency and vulnerability to later ASD diagnosis, with multidimensional developmental lags signaling vulnerability to ASD diagnosis. En ligne : http://dx.doi.org/10.1017/s0954579420000814 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

The role of caregiver speech in supporting language development in infants and toddlers with autism spectrum disorder / Meghan R. SWANSON in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1230-1239 Titre : The role of caregiver speech in supporting language development in infants and toddlers with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Meghan R. SWANSON, Auteur Article en page(s) : p.1230-1239 Langues : Anglais (eng) Mots-clés : Asd  autism spectrum disorder  caregiver speech  high familial risk  home language environment  language Index. décimale : PER Périodiques Résumé : Parents play an essential role in supporting child development by providing a safe home, proper nutrition, and rich educational opportunities. In this article we focus on the role of caregiver speech in supporting development of young children with autism spectrum disorder (ASD). We review studies from typically developing children and children with autism showing that rich and responsive caregiver speech supports language development. Autism intervention studies that target caregiver speech are reviewed as are recent scientific advances from studies of typical development. The strengths and weakness of different techniques for collecting language data from caregivers and children are reviewed, and natural language samples are recommended as best practice for language research in autism. We conclude that caregivers play a powerful role in shaping their children's development and encourage researchers to adapt parent-mediated intervention studies to acknowledge individual differences in parents by using a personalized medicine approach. En ligne : http://dx.doi.org/10.1017/s0954579420000838 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] The role of caregiver speech in supporting language development in infants and toddlers with autism spectrum disorder [Texte imprimé et/ou numérique] / Meghan R. SWANSON, Auteur . - p.1230-1239. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1230-1239 Mots-clés : Asd  autism spectrum disorder  caregiver speech  high familial risk  home language environment  language Index. décimale : PER Périodiques Résumé : Parents play an essential role in supporting child development by providing a safe home, proper nutrition, and rich educational opportunities. In this article we focus on the role of caregiver speech in supporting development of young children with autism spectrum disorder (ASD). We review studies from typically developing children and children with autism showing that rich and responsive caregiver speech supports language development. Autism intervention studies that target caregiver speech are reviewed as are recent scientific advances from studies of typical development. The strengths and weakness of different techniques for collecting language data from caregivers and children are reviewed, and natural language samples are recommended as best practice for language research in autism. We conclude that caregivers play a powerful role in shaping their children's development and encourage researchers to adapt parent-mediated intervention studies to acknowledge individual differences in parents by using a personalized medicine approach. En ligne : http://dx.doi.org/10.1017/s0954579420000838 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Atypical communication characteristics among clinic-referred youth with and without autism spectrum disorder: Stability and associations with clinical correlates / Erin KANG in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1240-1253 Titre : Atypical communication characteristics among clinic-referred youth with and without autism spectrum disorder: Stability and associations with clinical correlates Type de document : Texte imprimé et/ou numérique Auteurs : Erin KANG, Auteur ; Matthew D LERNER, Auteur ; Kenneth D GADOW, Auteur Article en page(s) : p.1240-1253 Langues : Anglais (eng) Mots-clés : atypical communication characteristics (ACC)  autism spectrum disorder (ASD)  comorbidity  latent class analysis Index. décimale : PER Périodiques Résumé : Atypical communication characteristics (ACCs), such as speech delay, odd pitch, and pragmatic difficulties, are common features of autism spectrum disorder (ASD) as are the symptoms of a wide range of psychiatric disorders. Using a simple retrospective method, this study aimed to better understand the relation and stability of ACCs with a broad range of psychiatric symptoms among large, well-characterized samples of clinic-referred children and adolescents with and without ASD. Youth with ASD had higher rates and a more variable pattern of developmental change in ACCs than the non-ASD diagnostic group. Latent class analysis yielded three ACC stability subgroups within ASD: Stable ACCs, Mostly Current-Only ACCs, and Little Professors. Subgroups exhibited differences in severity of ASD symptomatology, co-occurring psychiatric symptoms, and other correlates. Our findings provide support for the clinical utility of characterizing caregiver-perceived changes in ACCs in identifying children at risk for co-occurring psychopathology and other clinically relevant variables. En ligne : http://dx.doi.org/10.1017/s095457942000070x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Atypical communication characteristics among clinic-referred youth with and without autism spectrum disorder: Stability and associations with clinical correlates [Texte imprimé et/ou numérique] / Erin KANG, Auteur ; Matthew D LERNER, Auteur ; Kenneth D GADOW, Auteur . - p.1240-1253. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1240-1253 Mots-clés : atypical communication characteristics (ACC)  autism spectrum disorder (ASD)  comorbidity  latent class analysis Index. décimale : PER Périodiques Résumé : Atypical communication characteristics (ACCs), such as speech delay, odd pitch, and pragmatic difficulties, are common features of autism spectrum disorder (ASD) as are the symptoms of a wide range of psychiatric disorders. Using a simple retrospective method, this study aimed to better understand the relation and stability of ACCs with a broad range of psychiatric symptoms among large, well-characterized samples of clinic-referred children and adolescents with and without ASD. Youth with ASD had higher rates and a more variable pattern of developmental change in ACCs than the non-ASD diagnostic group. Latent class analysis yielded three ACC stability subgroups within ASD: Stable ACCs, Mostly Current-Only ACCs, and Little Professors. Subgroups exhibited differences in severity of ASD symptomatology, co-occurring psychiatric symptoms, and other correlates. Our findings provide support for the clinical utility of characterizing caregiver-perceived changes in ACCs in identifying children at risk for co-occurring psychopathology and other clinically relevant variables. En ligne : http://dx.doi.org/10.1017/s095457942000070x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

A conceptual model of risk and protective factors associated with internalizing symptoms in autism spectrum disorder: A scoping review, synthesis, and call for more research / Heather A. YARGER in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1254-1272 Titre : A conceptual model of risk and protective factors associated with internalizing symptoms in autism spectrum disorder: A scoping review, synthesis, and call for more research Type de document : Texte imprimé et/ou numérique Auteurs : Heather A. YARGER, Auteur ; Elizabeth REDCAY, Auteur Article en page(s) : p.1254-1272 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  child development  internalizing symptoms  protective factors  risk factors Index. décimale : PER Périodiques Résumé : This paper reviews and synthesizes key areas of research related to the etiology, development, and maintenance of internalizing symptoms in children, adolescents, and adults with autism spectrum disorder (ASD). In developing an integrated conceptual model, we draw from current conceptual models of internalizing symptoms in ASD and extend the model to include factors related to internalizing within other populations (e.g., children that have experienced early life stress, children with other neurodevelopmental conditions, typically developing children) that have not been systematically examined in ASD. Our review highlights the need for more research to understand the developmental course of internalizing symptoms, potential moderators, and the interplay between early risk and protective factors. Longitudinal studies incorporating multiple methods and both environmental and biological factors will be important in order to elucidate these mechanisms. En ligne : http://dx.doi.org/10.1017/s095457942000084x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] A conceptual model of risk and protective factors associated with internalizing symptoms in autism spectrum disorder: A scoping review, synthesis, and call for more research [Texte imprimé et/ou numérique] / Heather A. YARGER, Auteur ; Elizabeth REDCAY, Auteur . - p.1254-1272. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1254-1272 Mots-clés : autism spectrum disorder  child development  internalizing symptoms  protective factors  risk factors Index. décimale : PER Périodiques Résumé : This paper reviews and synthesizes key areas of research related to the etiology, development, and maintenance of internalizing symptoms in children, adolescents, and adults with autism spectrum disorder (ASD). In developing an integrated conceptual model, we draw from current conceptual models of internalizing symptoms in ASD and extend the model to include factors related to internalizing within other populations (e.g., children that have experienced early life stress, children with other neurodevelopmental conditions, typically developing children) that have not been systematically examined in ASD. Our review highlights the need for more research to understand the developmental course of internalizing symptoms, potential moderators, and the interplay between early risk and protective factors. Longitudinal studies incorporating multiple methods and both environmental and biological factors will be important in order to elucidate these mechanisms. En ligne : http://dx.doi.org/10.1017/s095457942000084x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Functional brain abnormalities associated with comorbid anxiety in autism spectrum disorder / James BARTOLOTTI in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1273-1286 Titre : Functional brain abnormalities associated with comorbid anxiety in autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : James BARTOLOTTI, Auteur ; John A. SWEENEY, Auteur ; Matthew W. MOSCONI, Auteur Article en page(s) : p.1273-1286 Langues : Anglais (eng) Mots-clés : amygdala  anxiety  autism  comorbid disorders  functional connectivity Index. décimale : PER Périodiques Résumé : Anxiety disorders are common in autism spectrum disorder (ASD) and associated with social-communication impairment and repetitive behavior symptoms. The neurobiology of anxiety in ASD is unknown, but amygdala dysfunction has been implicated in both ASD and anxiety disorders. Using resting-state functional magnetic resonance imaging, we compared amygdala-prefrontal and amygdala-striatal connections across three demographically matched groups studied in the Autism Brain Imaging Data Exchange (ABIDE): ASD with a comorbid anxiety disorder (N = 25; ASD + Anxiety), ASD without a comorbid disorder (N = 68; ASD-NoAnx), and typically developing controls (N = 139; TD). Relative to ASD-NoAnx and TD controls, ASD + Anxiety individuals had decreased connectivity between the amygdala and dorsal/rostral anterior cingulate cortex (dACC/rACC). The functional connectivity of these connections was not affected in ASD-NoAnx, and amygdala connectivity with ventral ACC/medial prefrontal cortex (mPFC) circuits was not different in ASD + Anxiety or ASD-NoAnx relative to TD. Decreased amygdala-dorsomedial prefrontal cortex (dmPFC)/rACC connectivity was associated with more severe social impairment in ASD + Anxiety; amygdala-striatal connectivity was associated with restricted, repetitive behavior (RRB) symptom severity in ASD-NoAnx individuals. These findings suggest comorbid anxiety in ASD is associated with disrupted emotion-monitoring processes supported by amygdala-dACC/mPFC pathways, whereas emotion regulation systems involving amygdala-ventromedial prefrontal cortex (vmPFC) are relatively spared. Our results highlight the importance of accounting for comorbid anxiety for parsing ASD neurobiological heterogeneity. En ligne : http://dx.doi.org/10.1017/s0954579420000772 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Functional brain abnormalities associated with comorbid anxiety in autism spectrum disorder [Texte imprimé et/ou numérique] / James BARTOLOTTI, Auteur ; John A. SWEENEY, Auteur ; Matthew W. MOSCONI, Auteur . - p.1273-1286. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1273-1286 Mots-clés : amygdala  anxiety  autism  comorbid disorders  functional connectivity Index. décimale : PER Périodiques Résumé : Anxiety disorders are common in autism spectrum disorder (ASD) and associated with social-communication impairment and repetitive behavior symptoms. The neurobiology of anxiety in ASD is unknown, but amygdala dysfunction has been implicated in both ASD and anxiety disorders. Using resting-state functional magnetic resonance imaging, we compared amygdala-prefrontal and amygdala-striatal connections across three demographically matched groups studied in the Autism Brain Imaging Data Exchange (ABIDE): ASD with a comorbid anxiety disorder (N = 25; ASD + Anxiety), ASD without a comorbid disorder (N = 68; ASD-NoAnx), and typically developing controls (N = 139; TD). Relative to ASD-NoAnx and TD controls, ASD + Anxiety individuals had decreased connectivity between the amygdala and dorsal/rostral anterior cingulate cortex (dACC/rACC). The functional connectivity of these connections was not affected in ASD-NoAnx, and amygdala connectivity with ventral ACC/medial prefrontal cortex (mPFC) circuits was not different in ASD + Anxiety or ASD-NoAnx relative to TD. Decreased amygdala-dorsomedial prefrontal cortex (dmPFC)/rACC connectivity was associated with more severe social impairment in ASD + Anxiety; amygdala-striatal connectivity was associated with restricted, repetitive behavior (RRB) symptom severity in ASD-NoAnx individuals. These findings suggest comorbid anxiety in ASD is associated with disrupted emotion-monitoring processes supported by amygdala-dACC/mPFC pathways, whereas emotion regulation systems involving amygdala-ventromedial prefrontal cortex (vmPFC) are relatively spared. Our results highlight the importance of accounting for comorbid anxiety for parsing ASD neurobiological heterogeneity. En ligne : http://dx.doi.org/10.1017/s0954579420000772 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Trajectories of co-occurring psychopathology symptoms in autism from late childhood to adulthood / James B. MCCAULEY in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1287-1302 Titre : Trajectories of co-occurring psychopathology symptoms in autism from late childhood to adulthood Type de document : Texte imprimé et/ou numérique Auteurs : James B. MCCAULEY, Auteur ; Rebecca ELIAS, Auteur ; Catherine LORD, Auteur Article en page(s) : p.1287-1302 Langues : Anglais (eng) Mots-clés : autism  co-occurring symptoms  development  longitudinal data  outcomes  trajectories Index. décimale : PER Périodiques Résumé : Given high rates of co-occurring conditions in youth and adults with autism spectrum disorder (ASD), it is critical to examine the developmental trajectories of these symptoms of psychopathology. Using data from a cohort of participants (n = 194), most of whom were first assessed for ASD in very early childhood, we investigated the trajectories of co-occurring depressive, anxiety, and attention-deficit hyperactivity disorder (ADHD) symptoms from late childhood to adulthood. Additionally, childhood predictors and adult outcomes associated with these symptom trajectories were examined. Using group-based trajectory modeling, we found two distinct classes of individuals exhibiting each of these co-occurring symptom patterns: one class exhibited fairly low symptoms across time, and one class with elevated symptoms with varied fluctuation across time (ADHD symptoms starting high but decreasing, anxiety symptoms high and stable, and depressive symptoms fluctuating but peaking at clinically significant levels in young adulthood). All high trajectory classes were associated with age 9 adaptive skills; verbal IQ predicted higher anxiety and depressive symptom classes. After accounting for verbal IQ, all high symptom trajectory classes were negative predictors of objective adult outcomes. These findings call for wide-ranging considerations of the needs of individuals across ability levels, autism symptoms, and behavioral and emotional challenges. En ligne : http://dx.doi.org/10.1017/s0954579420000826 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Trajectories of co-occurring psychopathology symptoms in autism from late childhood to adulthood [Texte imprimé et/ou numérique] / James B. MCCAULEY, Auteur ; Rebecca ELIAS, Auteur ; Catherine LORD, Auteur . - p.1287-1302. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1287-1302 Mots-clés : autism  co-occurring symptoms  development  longitudinal data  outcomes  trajectories Index. décimale : PER Périodiques Résumé : Given high rates of co-occurring conditions in youth and adults with autism spectrum disorder (ASD), it is critical to examine the developmental trajectories of these symptoms of psychopathology. Using data from a cohort of participants (n = 194), most of whom were first assessed for ASD in very early childhood, we investigated the trajectories of co-occurring depressive, anxiety, and attention-deficit hyperactivity disorder (ADHD) symptoms from late childhood to adulthood. Additionally, childhood predictors and adult outcomes associated with these symptom trajectories were examined. Using group-based trajectory modeling, we found two distinct classes of individuals exhibiting each of these co-occurring symptom patterns: one class exhibited fairly low symptoms across time, and one class with elevated symptoms with varied fluctuation across time (ADHD symptoms starting high but decreasing, anxiety symptoms high and stable, and depressive symptoms fluctuating but peaking at clinically significant levels in young adulthood). All high trajectory classes were associated with age 9 adaptive skills; verbal IQ predicted higher anxiety and depressive symptom classes. After accounting for verbal IQ, all high symptom trajectory classes were negative predictors of objective adult outcomes. These findings call for wide-ranging considerations of the needs of individuals across ability levels, autism symptoms, and behavioral and emotional challenges. En ligne : http://dx.doi.org/10.1017/s0954579420000826 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Look duration at the face as a developmental endophenotype: elucidating pathways to autism and ADHD / Anna GUI in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1303-1322 Titre : Look duration at the face as a developmental endophenotype: elucidating pathways to autism and ADHD Type de document : Texte imprimé et/ou numérique Auteurs : Anna GUI, Auteur ; Luke MASON, Auteur ; Teodora GLIGA, Auteur ; Alexandra HENDRY, Auteur ; Jannath BEGUM ALI, Auteur ; Greg PASCO, Auteur ; Elizabeth SHEPHARD, Auteur ; Charles CURTIS, Auteur ; Tony CHARMAN, Auteur ; Mark H. JOHNSON, Auteur ; Emma MEABURN, Auteur ; Emily J. H. JONES, Auteur Article en page(s) : p.1303-1322 Langues : Anglais (eng) Mots-clés : attention  endophenotypes  eye-tracking  infant siblings  polygenic score Index. décimale : PER Périodiques Résumé : Identifying developmental endophenotypes on the pathway between genetics and behavior is critical to uncovering the mechanisms underlying neurodevelopmental conditions. In this proof-of-principle study, we explored whether early disruptions in visual attention are a unique or shared candidate endophenotype of autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD). We calculated the duration of the longest look (i.e., peak look) to faces in an array-based eye-tracking task for 335 14-month-old infants with and without first-degree relatives with ASD and/or ADHD. We leveraged parent-report and genotype data available for a proportion of these infants to evaluate the relation of looking behavior to familial (n = 285) and genetic liability (using polygenic scores, n = 185) as well as ASD and ADHD-relevant temperament traits at 2 years of age (shyness and inhibitory control, respectively, n = 272) and ASD and ADHD clinical traits at 6 years of age (n = 94).Results showed that longer peak looks at the face were associated with elevated polygenic scores for ADHD (? = 0.078, p = .023), but not ASD (? = 0.002, p = .944), and with elevated ADHD traits in mid-childhood (F(1,88) = 6.401, p = .013, $\eta _p^2$=0.068; ASD: F (1,88) = 3.218, p = .076), but not in toddlerhood (ps > 0.2). This pattern of results did not emerge when considering mean peak look duration across face and nonface stimuli. Thus, alterations in attention to faces during spontaneous visual exploration may be more consistent with a developmental endophenotype of ADHD than ASD. Our work shows that dissecting paths to neurodevelopmental conditions requires longitudinal data incorporating polygenic contribution, early neurocognitive function, and clinical phenotypic variation. En ligne : http://dx.doi.org/10.1017/s0954579420000930 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Look duration at the face as a developmental endophenotype: elucidating pathways to autism and ADHD [Texte imprimé et/ou numérique] / Anna GUI, Auteur ; Luke MASON, Auteur ; Teodora GLIGA, Auteur ; Alexandra HENDRY, Auteur ; Jannath BEGUM ALI, Auteur ; Greg PASCO, Auteur ; Elizabeth SHEPHARD, Auteur ; Charles CURTIS, Auteur ; Tony CHARMAN, Auteur ; Mark H. JOHNSON, Auteur ; Emma MEABURN, Auteur ; Emily J. H. JONES, Auteur . - p.1303-1322. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1303-1322 Mots-clés : attention  endophenotypes  eye-tracking  infant siblings  polygenic score Index. décimale : PER Périodiques Résumé : Identifying developmental endophenotypes on the pathway between genetics and behavior is critical to uncovering the mechanisms underlying neurodevelopmental conditions. In this proof-of-principle study, we explored whether early disruptions in visual attention are a unique or shared candidate endophenotype of autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD). We calculated the duration of the longest look (i.e., peak look) to faces in an array-based eye-tracking task for 335 14-month-old infants with and without first-degree relatives with ASD and/or ADHD. We leveraged parent-report and genotype data available for a proportion of these infants to evaluate the relation of looking behavior to familial (n = 285) and genetic liability (using polygenic scores, n = 185) as well as ASD and ADHD-relevant temperament traits at 2 years of age (shyness and inhibitory control, respectively, n = 272) and ASD and ADHD clinical traits at 6 years of age (n = 94).Results showed that longer peak looks at the face were associated with elevated polygenic scores for ADHD (? = 0.078, p = .023), but not ASD (? = 0.002, p = .944), and with elevated ADHD traits in mid-childhood (F(1,88) = 6.401, p = .013, $\eta _p^2$=0.068; ASD: F (1,88) = 3.218, p = .076), but not in toddlerhood (ps > 0.2). This pattern of results did not emerge when considering mean peak look duration across face and nonface stimuli. Thus, alterations in attention to faces during spontaneous visual exploration may be more consistent with a developmental endophenotype of ADHD than ASD. Our work shows that dissecting paths to neurodevelopmental conditions requires longitudinal data incorporating polygenic contribution, early neurocognitive function, and clinical phenotypic variation. En ligne : http://dx.doi.org/10.1017/s0954579420000930 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Shared and distinct developmental pathways to ASD and ADHD phenotypes among infants at familial risk / Meghan MILLER in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1323-1334 Titre : Shared and distinct developmental pathways to ASD and ADHD phenotypes among infants at familial risk Type de document : Texte imprimé et/ou numérique Auteurs : Meghan MILLER, Auteur ; Shane AUSTIN, Auteur ; Ana-Maria IOSIF, Auteur ; Leiana DE LA PAZ, Auteur ; Annie CHUANG, Auteur ; Burt HATCH, Auteur ; Sally OZONOFF, Auteur Article en page(s) : p.1323-1334 Langues : Anglais (eng) Mots-clés : Adhd  autism  early childhood  infancy  latent profile analysis Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are believed to share partially overlapping causal mechanisms suggesting that early risk markers may also overlap. Using latent profile analysis (LPA) in a sample of infants enriched for ASD and ADHD, we first examined the number of distinct groups of 3-year-old children, based on ADHD and ASD symptomatology. To investigate early predictors of ASD and ADHD symptom profiles, we next examined differences in trajectories of infant behaviors among the LPA classes spanning general development, negative affect, attention, activity level, impulsivity, and social behavior. Participants included 166 infants at familial risk for ASD (n = 89), ADHD (n = 38), or low-risk for both (n = 39) evaluated at 12, 18, 24, and 36 months of age. A three-class solution was selected reflecting a Typically Developing (TD) class (low symptoms; n = 108), an ADHD class (high ADHD/low ASD symptoms; n = 39), and an ASD class (high ASD/ADHD symptoms; n = 19). Trajectories of infant behaviors were generally suggestive of a gradient pattern of differences, with the greatest impairment within the ASD class followed by the ADHD class. These findings indicate a mixture of overlapping and distinct early markers of preschool ASD- and ADHD-like profiles that can be difficult to disentangle early in life. En ligne : http://dx.doi.org/10.1017/s0954579420000735 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Shared and distinct developmental pathways to ASD and ADHD phenotypes among infants at familial risk [Texte imprimé et/ou numérique] / Meghan MILLER, Auteur ; Shane AUSTIN, Auteur ; Ana-Maria IOSIF, Auteur ; Leiana DE LA PAZ, Auteur ; Annie CHUANG, Auteur ; Burt HATCH, Auteur ; Sally OZONOFF, Auteur . - p.1323-1334. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1323-1334 Mots-clés : Adhd  autism  early childhood  infancy  latent profile analysis Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are believed to share partially overlapping causal mechanisms suggesting that early risk markers may also overlap. Using latent profile analysis (LPA) in a sample of infants enriched for ASD and ADHD, we first examined the number of distinct groups of 3-year-old children, based on ADHD and ASD symptomatology. To investigate early predictors of ASD and ADHD symptom profiles, we next examined differences in trajectories of infant behaviors among the LPA classes spanning general development, negative affect, attention, activity level, impulsivity, and social behavior. Participants included 166 infants at familial risk for ASD (n = 89), ADHD (n = 38), or low-risk for both (n = 39) evaluated at 12, 18, 24, and 36 months of age. A three-class solution was selected reflecting a Typically Developing (TD) class (low symptoms; n = 108), an ADHD class (high ADHD/low ASD symptoms; n = 39), and an ASD class (high ASD/ADHD symptoms; n = 19). Trajectories of infant behaviors were generally suggestive of a gradient pattern of differences, with the greatest impairment within the ASD class followed by the ADHD class. These findings indicate a mixture of overlapping and distinct early markers of preschool ASD- and ADHD-like profiles that can be difficult to disentangle early in life. En ligne : http://dx.doi.org/10.1017/s0954579420000735 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Emergence and rate of autism in fragile X syndrome across the first years of life / Jane E. ROBERTS in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1335-1352 Titre : Emergence and rate of autism in fragile X syndrome across the first years of life Type de document : Texte imprimé et/ou numérique Auteurs : Jane E. ROBERTS, Auteur ; Jessica BRADSHAW, Auteur ; Elizabeth A. WILL, Auteur ; Abigail L. HOGAN, Auteur ; Samuel MCQUILLIN, Auteur ; Kimberly HILLS, Auteur Article en page(s) : p.1335-1352 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  developmental trajectory  early identification  fragile X syndrome  infants Index. décimale : PER Périodiques Résumé : Prospective longitudinal studies of idiopathic autism spectrum disorder (ASD) have provided insights into early symptoms and predictors of ASD during infancy, well before ASD can be diagnosed at age 2-3 years. However, research on the emergence of ASD in disorders with a known genetic etiology, contextualized in a developmental framework, is currently lacking. Using a biobehavioral multimethod approach, we (a) determined the rate of ASD in N = 51 preschoolers with fragile X syndrome (FXS) using a clinical best estimate (CBE) procedure with differential diagnoses of comorbid psychiatric disorders and (b) investigated trajectories of ASD symptoms and physiological arousal across infancy as predictors of ASD in preschoolers with FXS. ASD was not diagnosed if intellectual ability or psychiatric disorders better accounted for the symptoms. Our results determined that 60.7% of preschoolers with FXS met the Diagnostic and Statistical Manual of Mental Disorders (fifth edition) (DSM-5) criteria for ASD using the CBE procedure. In addition, 92% of these preschoolers presented with developmental delay and 45.4% also met criteria for psychiatric disorders, either anxiety, ADHD, or both. ASD diagnoses in preschoolers with FXS were predicted by elevated scores on traditional ASD screeners in addition to elevated autonomic arousal and avoidant eye contact from infancy. En ligne : http://dx.doi.org/10.1017/s0954579420000942 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Emergence and rate of autism in fragile X syndrome across the first years of life [Texte imprimé et/ou numérique] / Jane E. ROBERTS, Auteur ; Jessica BRADSHAW, Auteur ; Elizabeth A. WILL, Auteur ; Abigail L. HOGAN, Auteur ; Samuel MCQUILLIN, Auteur ; Kimberly HILLS, Auteur . - p.1335-1352. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1335-1352 Mots-clés : autism spectrum disorder  developmental trajectory  early identification  fragile X syndrome  infants Index. décimale : PER Périodiques Résumé : Prospective longitudinal studies of idiopathic autism spectrum disorder (ASD) have provided insights into early symptoms and predictors of ASD during infancy, well before ASD can be diagnosed at age 2-3 years. However, research on the emergence of ASD in disorders with a known genetic etiology, contextualized in a developmental framework, is currently lacking. Using a biobehavioral multimethod approach, we (a) determined the rate of ASD in N = 51 preschoolers with fragile X syndrome (FXS) using a clinical best estimate (CBE) procedure with differential diagnoses of comorbid psychiatric disorders and (b) investigated trajectories of ASD symptoms and physiological arousal across infancy as predictors of ASD in preschoolers with FXS. ASD was not diagnosed if intellectual ability or psychiatric disorders better accounted for the symptoms. Our results determined that 60.7% of preschoolers with FXS met the Diagnostic and Statistical Manual of Mental Disorders (fifth edition) (DSM-5) criteria for ASD using the CBE procedure. In addition, 92% of these preschoolers presented with developmental delay and 45.4% also met criteria for psychiatric disorders, either anxiety, ADHD, or both. ASD diagnoses in preschoolers with FXS were predicted by elevated scores on traditional ASD screeners in addition to elevated autonomic arousal and avoidant eye contact from infancy. En ligne : http://dx.doi.org/10.1017/s0954579420000942 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Transcriptional subtyping explains phenotypic variability in genetic subtypes of autism spectrum disorder / Sandy TRINH in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1353-1361 Titre : Transcriptional subtyping explains phenotypic variability in genetic subtypes of autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Sandy TRINH, Auteur ; Anne B. ARNETT, Auteur ; Evangeline KURTZ-NELSON, Auteur ; Jennifer BEIGHLEY, Auteur ; Marta PICOTO, Auteur ; Raphael BERNIER, Auteur Article en page(s) : p.1353-1361 Langues : Anglais (eng) Mots-clés : autism  genetics  mutation  organization or entity with any financial interest in the outcome of this project. Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is a common neurodevelopmental disorder characterized by deficits in social communication and presence of restricted, repetitive behaviors, and interests. However, individuals with ASD vary significantly in their challenges and abilities in these and other developmental domains. Gene discovery in ASD has accelerated in the past decade, and genetic subtyping has yielded preliminary evidence of utility in parsing phenotypic heterogeneity through genomic subtypes. Recent advances in transcriptomics have provided additional dimensions with which to refine genetic subtyping efforts. In the current study, we investigate phenotypic differences among transcriptional subtypes defined by neurobiological spatiotemporal co-expression patterns. Of the four transcriptional subtypes examined, participants with mutations to genes typically expressed highly in all brain regions prenatally, and those with differential postnatal cerebellar expression relative to other brain regions, showed lower cognitive and adaptive skills, higher severity of social communication deficits, and later acquisition of speech and motor milestones, compared to those with mutations to genes highly expressed during the postnatal period across brain regions. These findings suggest higher-order characterization of genetic subtypes based on neurobiological expression patterns may be a promising approach to parsing phenotypic heterogeneity among those with ASD and related neurodevelopmental disorders. En ligne : http://dx.doi.org/10.1017/s0954579420000784 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Transcriptional subtyping explains phenotypic variability in genetic subtypes of autism spectrum disorder [Texte imprimé et/ou numérique] / Sandy TRINH, Auteur ; Anne B. ARNETT, Auteur ; Evangeline KURTZ-NELSON, Auteur ; Jennifer BEIGHLEY, Auteur ; Marta PICOTO, Auteur ; Raphael BERNIER, Auteur . - p.1353-1361. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1353-1361 Mots-clés : autism  genetics  mutation  organization or entity with any financial interest in the outcome of this project. Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is a common neurodevelopmental disorder characterized by deficits in social communication and presence of restricted, repetitive behaviors, and interests. However, individuals with ASD vary significantly in their challenges and abilities in these and other developmental domains. Gene discovery in ASD has accelerated in the past decade, and genetic subtyping has yielded preliminary evidence of utility in parsing phenotypic heterogeneity through genomic subtypes. Recent advances in transcriptomics have provided additional dimensions with which to refine genetic subtyping efforts. In the current study, we investigate phenotypic differences among transcriptional subtypes defined by neurobiological spatiotemporal co-expression patterns. Of the four transcriptional subtypes examined, participants with mutations to genes typically expressed highly in all brain regions prenatally, and those with differential postnatal cerebellar expression relative to other brain regions, showed lower cognitive and adaptive skills, higher severity of social communication deficits, and later acquisition of speech and motor milestones, compared to those with mutations to genes highly expressed during the postnatal period across brain regions. These findings suggest higher-order characterization of genetic subtypes based on neurobiological expression patterns may be a promising approach to parsing phenotypic heterogeneity among those with ASD and related neurodevelopmental disorders. En ligne : http://dx.doi.org/10.1017/s0954579420000784 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Social origins of self-regulated attention during infancy and their disruption in autism spectrum disorder: Implications for early intervention / Michael S. GAFFREY in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1362-1374 Titre : Social origins of self-regulated attention during infancy and their disruption in autism spectrum disorder: Implications for early intervention Type de document : Texte imprimé et/ou numérique Auteurs : Michael S. GAFFREY, Auteur ; Sarah MARKERT, Auteur ; Chen YU, Auteur Article en page(s) : p.1362-1374 Langues : Anglais (eng) Mots-clés : autism  autism spectrum disorder  eye tracking  infant  joint attention Index. décimale : PER Périodiques Résumé : To understand the complex relationships between autism spectrum disorder (ASD) and other frequently comorbid conditions, a growing number of studies have investigated the emergence of ASD during infancy. This research has suggested that symptoms of ASD and highly related comorbid conditions emerge from complex interactions between neurodevelopmental vulnerabilities and early environments, indicating that developing treatments to prevent ASD is highly challenging. However, it also suggests that attenuating the negative effects of ASD on future development once identified is possible. The present paper builds on this by conceptualizing developmental delays in nonsocial skills as the potential product of altered caregiver-infant interactions following the emergence of ASD during infancy. And, following emerging findings from caregiver-infant dyadic head-mounted eye-tracking (D-ET) research, it also suggests that a multiple pathway model of joint attention can provide mechanistic insights into how ASD alters the ability of caregiver and infant to create a context for infant learning. The potential for this view to inform early intervention is further discussed and illustrated through D-ET data collected prior to and following a brief, parent-mediated intervention for infant ASD. While promising, further research informing how a multiple pathway model of joint attention can inform ASD early intervention is needed. En ligne : http://dx.doi.org/10.1017/s0954579420000796 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Social origins of self-regulated attention during infancy and their disruption in autism spectrum disorder: Implications for early intervention [Texte imprimé et/ou numérique] / Michael S. GAFFREY, Auteur ; Sarah MARKERT, Auteur ; Chen YU, Auteur . - p.1362-1374. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1362-1374 Mots-clés : autism  autism spectrum disorder  eye tracking  infant  joint attention Index. décimale : PER Périodiques Résumé : To understand the complex relationships between autism spectrum disorder (ASD) and other frequently comorbid conditions, a growing number of studies have investigated the emergence of ASD during infancy. This research has suggested that symptoms of ASD and highly related comorbid conditions emerge from complex interactions between neurodevelopmental vulnerabilities and early environments, indicating that developing treatments to prevent ASD is highly challenging. However, it also suggests that attenuating the negative effects of ASD on future development once identified is possible. The present paper builds on this by conceptualizing developmental delays in nonsocial skills as the potential product of altered caregiver-infant interactions following the emergence of ASD during infancy. And, following emerging findings from caregiver-infant dyadic head-mounted eye-tracking (D-ET) research, it also suggests that a multiple pathway model of joint attention can provide mechanistic insights into how ASD alters the ability of caregiver and infant to create a context for infant learning. The potential for this view to inform early intervention is further discussed and illustrated through D-ET data collected prior to and following a brief, parent-mediated intervention for infant ASD. While promising, further research informing how a multiple pathway model of joint attention can inform ASD early intervention is needed. En ligne : http://dx.doi.org/10.1017/s0954579420000796 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

The codevelopment of internalizing symptoms, externalizing symptoms, and cognitive ability across childhood and adolescence / Efstathios PAPACHRISTOU in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1375-1389 Titre : The codevelopment of internalizing symptoms, externalizing symptoms, and cognitive ability across childhood and adolescence Type de document : Texte imprimé et/ou numérique Auteurs : Efstathios PAPACHRISTOU, Auteur ; Eirini FLOURI, Auteur Article en page(s) : p.1375-1389 Langues : Anglais (eng) Mots-clés : adolescence  childhood  cognitive ability  externalizing symptoms  internalizing symptoms  trajectories Index. décimale : PER Périodiques Résumé : Cognitive ability, externalizing symptoms, and internalizing symptoms are correlated in children. However, it is not known why they combine in the general child population over time. To address this, we used data on 17,318 children participating in the UK Millennium Cohort Study and followed-up five times between ages 3 and 14 years. We fitted three parallel-process latent growth curve models to identify the parallel unfolding of children's trajectories of internalizing symptoms, externalizing symptoms, and cognitive ability across this period. We also examined the effects of time-invariant (ethnicity, birth weight, maternal education and age at birth, and breastfeeding status) and time-varying covariates (maternal psychological distress and socioeconomic disadvantage) on the growth parameters of the trajectories. The results showed that the intercepts of the trajectories of cognitive ability and, particularly, externalizing symptoms were inversely correlated. Their linear slopes were also inversely correlated, suggesting parallel development. Internalizing symptoms were correlated positively with externalizing symptoms and inversely (and more modestly) with cognitive ability at baseline, but the slope of internalizing symptoms correlated (positively) only with the slope of externalizing symptoms. The covariates predicted 9% to 41% of the variance in the intercepts and slopes of all domains, suggesting they are important common risk factors. Overall, it appears that externalizing symptoms develop in parallel with both cognitive ability and internalizing symptoms from early childhood through to middle adolescence. Children on an increasing trajectory of externalizing symptoms are likely both increasing in internalizing symptoms and decreasing in cognitive skills as well, and are thus an important group to target for intervention. En ligne : http://dx.doi.org/10.1017/s0954579419001330 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] The codevelopment of internalizing symptoms, externalizing symptoms, and cognitive ability across childhood and adolescence [Texte imprimé et/ou numérique] / Efstathios PAPACHRISTOU, Auteur ; Eirini FLOURI, Auteur . - p.1375-1389. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1375-1389 Mots-clés : adolescence  childhood  cognitive ability  externalizing symptoms  internalizing symptoms  trajectories Index. décimale : PER Périodiques Résumé : Cognitive ability, externalizing symptoms, and internalizing symptoms are correlated in children. However, it is not known why they combine in the general child population over time. To address this, we used data on 17,318 children participating in the UK Millennium Cohort Study and followed-up five times between ages 3 and 14 years. We fitted three parallel-process latent growth curve models to identify the parallel unfolding of children's trajectories of internalizing symptoms, externalizing symptoms, and cognitive ability across this period. We also examined the effects of time-invariant (ethnicity, birth weight, maternal education and age at birth, and breastfeeding status) and time-varying covariates (maternal psychological distress and socioeconomic disadvantage) on the growth parameters of the trajectories. The results showed that the intercepts of the trajectories of cognitive ability and, particularly, externalizing symptoms were inversely correlated. Their linear slopes were also inversely correlated, suggesting parallel development. Internalizing symptoms were correlated positively with externalizing symptoms and inversely (and more modestly) with cognitive ability at baseline, but the slope of internalizing symptoms correlated (positively) only with the slope of externalizing symptoms. The covariates predicted 9% to 41% of the variance in the intercepts and slopes of all domains, suggesting they are important common risk factors. Overall, it appears that externalizing symptoms develop in parallel with both cognitive ability and internalizing symptoms from early childhood through to middle adolescence. Children on an increasing trajectory of externalizing symptoms are likely both increasing in internalizing symptoms and decreasing in cognitive skills as well, and are thus an important group to target for intervention. En ligne : http://dx.doi.org/10.1017/s0954579419001330 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Psychophysiological influences on personality trajectories in adolescent females exposed to child maltreatment / Raha HASSAN in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1390-1401 Titre : Psychophysiological influences on personality trajectories in adolescent females exposed to child maltreatment Type de document : Texte imprimé et/ou numérique Auteurs : Raha HASSAN, Auteur ; Harriet L. MACMILLAN, Auteur ; Masako TANAKA, Auteur ; Louis A. SCHMIDT, Auteur Article en page(s) : p.1390-1401 Langues : Anglais (eng) Mots-clés : Eeg  child maltreatment  extraversion  neuroticism  respiratory sinus arrhythmia Index. décimale : PER Périodiques Résumé : Although child maltreatment is a major public health concern, which adversely affects psychological and physical development, we know relatively little concerning psychophysiological and personality factors that may modify risk in children exposed to maltreatment. Using a three-wave, short-term prospective design, we examined the influence of individual differences in two disparate psychophysiological measures of risk (i.e., resting frontal brain electrical activity and respiratory sinus arrhythmia) on the trajectories of extraversion and neuroticism in a sample of female adolescents (N = 55; M age = 14.02 years) exposed to child maltreatment. Adolescents exposed to child maltreatment with relatively higher left frontal absolute alpha power (i.e., lower brain activity) at rest exhibited increasing trajectories of extraversion, and adolescents exposed to child maltreatment with relatively lower respiratory sinus arrhythmia at rest displayed increasing trajectories of neuroticism over 1 year. Individual differences in psychophysiological measures indexing resting central and peripheral nervous system activity may therefore differentially influence personality characteristics in adolescent females exposed to child maltreatment. En ligne : http://dx.doi.org/10.1017/s0954579419001342 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Psychophysiological influences on personality trajectories in adolescent females exposed to child maltreatment [Texte imprimé et/ou numérique] / Raha HASSAN, Auteur ; Harriet L. MACMILLAN, Auteur ; Masako TANAKA, Auteur ; Louis A. SCHMIDT, Auteur . - p.1390-1401. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1390-1401 Mots-clés : Eeg  child maltreatment  extraversion  neuroticism  respiratory sinus arrhythmia Index. décimale : PER Périodiques Résumé : Although child maltreatment is a major public health concern, which adversely affects psychological and physical development, we know relatively little concerning psychophysiological and personality factors that may modify risk in children exposed to maltreatment. Using a three-wave, short-term prospective design, we examined the influence of individual differences in two disparate psychophysiological measures of risk (i.e., resting frontal brain electrical activity and respiratory sinus arrhythmia) on the trajectories of extraversion and neuroticism in a sample of female adolescents (N = 55; M age = 14.02 years) exposed to child maltreatment. Adolescents exposed to child maltreatment with relatively higher left frontal absolute alpha power (i.e., lower brain activity) at rest exhibited increasing trajectories of extraversion, and adolescents exposed to child maltreatment with relatively lower respiratory sinus arrhythmia at rest displayed increasing trajectories of neuroticism over 1 year. Individual differences in psychophysiological measures indexing resting central and peripheral nervous system activity may therefore differentially influence personality characteristics in adolescent females exposed to child maltreatment. En ligne : http://dx.doi.org/10.1017/s0954579419001342 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

The social withdrawal and social anxiety feedback loop and the role of peer victimization and acceptance in the pathways / Stefania A. BARZEVA in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1402-1417 Titre : The social withdrawal and social anxiety feedback loop and the role of peer victimization and acceptance in the pathways Type de document : Texte imprimé et/ou numérique Auteurs : Stefania A. BARZEVA, Auteur ; Jennifer S. RICHARDS, Auteur ; Wim H. J. MEEUS, Auteur ; Albertine J. OLDEHINKEL, Auteur Article en page(s) : p.1402-1417 Langues : Anglais (eng) Mots-clés : peer acceptance  peer victimization  random intercept cross-lagged panel model  social anxiety  social withdrawal Index. décimale : PER Périodiques Résumé : Social withdrawal and social anxiety are believed to have a bidirectional influence on one another, but it is unknown if their relationship is bidirectional, especially within person, and if peer experiences influence this relationship. We investigated temporal sequencing and the strength of effects between social withdrawal and social anxiety, and the roles of peer victimization and acceptance in the pathways. Participants were 2,772 adolescents from the population-based and clinically referred cohorts of the Tracking Adolescents' Individual Lives Survey. Self- and parent-reported withdrawal, and self-reported social anxiety, peer victimization, and perceived peer acceptance were assessed at 11, 13, and 16 years. Random-intercept cross-lagged panel models were used to investigate within-person associations between these variables. There was no feedback loop between withdrawal and social anxiety. Social withdrawal did not predict social anxiety at any age. Social anxiety at 11 years predicted increased self-reported withdrawal at 13 years. Negative peer experiences predicted increased self- and parent-reported withdrawal at 13 years and increased parent-reported withdrawal at 16 years. In turn, self-reported withdrawal at 13 years predicted negative peer experiences at 16 years. In conclusion, adolescents became more withdrawn when they became more socially anxious or experienced greater peer problems, and increasing withdrawal predicted greater victimization and lower acceptance. En ligne : http://dx.doi.org/10.1017/s0954579419001354 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] The social withdrawal and social anxiety feedback loop and the role of peer victimization and acceptance in the pathways [Texte imprimé et/ou numérique] / Stefania A. BARZEVA, Auteur ; Jennifer S. RICHARDS, Auteur ; Wim H. J. MEEUS, Auteur ; Albertine J. OLDEHINKEL, Auteur . - p.1402-1417. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1402-1417 Mots-clés : peer acceptance  peer victimization  random intercept cross-lagged panel model  social anxiety  social withdrawal Index. décimale : PER Périodiques Résumé : Social withdrawal and social anxiety are believed to have a bidirectional influence on one another, but it is unknown if their relationship is bidirectional, especially within person, and if peer experiences influence this relationship. We investigated temporal sequencing and the strength of effects between social withdrawal and social anxiety, and the roles of peer victimization and acceptance in the pathways. Participants were 2,772 adolescents from the population-based and clinically referred cohorts of the Tracking Adolescents' Individual Lives Survey. Self- and parent-reported withdrawal, and self-reported social anxiety, peer victimization, and perceived peer acceptance were assessed at 11, 13, and 16 years. Random-intercept cross-lagged panel models were used to investigate within-person associations between these variables. There was no feedback loop between withdrawal and social anxiety. Social withdrawal did not predict social anxiety at any age. Social anxiety at 11 years predicted increased self-reported withdrawal at 13 years. Negative peer experiences predicted increased self- and parent-reported withdrawal at 13 years and increased parent-reported withdrawal at 16 years. In turn, self-reported withdrawal at 13 years predicted negative peer experiences at 16 years. In conclusion, adolescents became more withdrawn when they became more socially anxious or experienced greater peer problems, and increasing withdrawal predicted greater victimization and lower acceptance. En ligne : http://dx.doi.org/10.1017/s0954579419001354 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Adverse childhood experiences: Mechanisms of risk and resilience in a longitudinal urban cohort / Alison GIOVANELLI in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1418-1439 Titre : Adverse childhood experiences: Mechanisms of risk and resilience in a longitudinal urban cohort Type de document : Texte imprimé et/ou numérique Auteurs : Alison GIOVANELLI, Auteur ; Christina F. MONDI, Auteur ; Arthur J. REYNOLDS, Auteur ; Suh-Ruu OU, Auteur Article en page(s) : p.1418-1439 Langues : Anglais (eng) Mots-clés : ACEs  generative mechanisms  risk and resilience  underserved communities Index. décimale : PER Périodiques Résumé : There is an extensive literature describing the detrimental effects of adverse childhood experiences (ACE; e.g., abuse, neglect, and household dysfunction) on physical and mental health. However, few large-scale studies have explored these associations longitudinally in urban minority cohorts or assessed links to broader measures of well-being such as educational attainment, occupation, and crime. Although adversity and resilience have long been of interest in developmental psychology, protective and promotive factors have been understudied in the ACE literature. This paper investigates the psychosocial processes through which ACEs contribute to outcomes, in addition to exploring ways to promote resilience to ACEs in vulnerable populations. Follow-up data were analyzed for 87% of the original 1,539 participants in the Chicago Longitudinal Study (N = 1,341), a prospective investigation of the impact of an Early Childhood Education program and early experiences on life-course well-being. Findings suggest that ACEs impact well-being in low-socioeconomic status participants above and beyond the effects of demographic risk and poverty, and point to possible mechanisms of transmission of ACE effects. Results also identify key areas across the ecological system that may promote resilience to ACEs, and speak to the need to continue to support underserved communities in active ways. En ligne : http://dx.doi.org/10.1017/s095457941900138x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Adverse childhood experiences: Mechanisms of risk and resilience in a longitudinal urban cohort [Texte imprimé et/ou numérique] / Alison GIOVANELLI, Auteur ; Christina F. MONDI, Auteur ; Arthur J. REYNOLDS, Auteur ; Suh-Ruu OU, Auteur . - p.1418-1439. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1418-1439 Mots-clés : ACEs  generative mechanisms  risk and resilience  underserved communities Index. décimale : PER Périodiques Résumé : There is an extensive literature describing the detrimental effects of adverse childhood experiences (ACE; e.g., abuse, neglect, and household dysfunction) on physical and mental health. However, few large-scale studies have explored these associations longitudinally in urban minority cohorts or assessed links to broader measures of well-being such as educational attainment, occupation, and crime. Although adversity and resilience have long been of interest in developmental psychology, protective and promotive factors have been understudied in the ACE literature. This paper investigates the psychosocial processes through which ACEs contribute to outcomes, in addition to exploring ways to promote resilience to ACEs in vulnerable populations. Follow-up data were analyzed for 87% of the original 1,539 participants in the Chicago Longitudinal Study (N = 1,341), a prospective investigation of the impact of an Early Childhood Education program and early experiences on life-course well-being. Findings suggest that ACEs impact well-being in low-socioeconomic status participants above and beyond the effects of demographic risk and poverty, and point to possible mechanisms of transmission of ACE effects. Results also identify key areas across the ecological system that may promote resilience to ACEs, and speak to the need to continue to support underserved communities in active ways. En ligne : http://dx.doi.org/10.1017/s095457941900138x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

The Young Adolescent Project: A longitudinal study of the effects of maltreatment on adolescent development / Sonya NEGRIFF in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1440-1459 Titre : The Young Adolescent Project: A longitudinal study of the effects of maltreatment on adolescent development Type de document : Texte imprimé et/ou numérique Auteurs : Sonya NEGRIFF, Auteur ; Elana B. GORDIS, Auteur ; Elizabeth J. SUSMAN, Auteur ; Kihyun KIM, Auteur ; Melissa K. PECKINS, Auteur ; Janet U. SCHNEIDERMAN, Auteur ; Ferol E. MENNEN, Auteur Article en page(s) : p.1440-1459 Langues : Anglais (eng) Mots-clés : adolescence  child maltreatment  longitudinal study Index. décimale : PER Périodiques Résumé : The Young Adolescent Project (YAP) is an ongoing longitudinal study investigating the effects of abuse and neglect on adolescent development. It is a multidisciplinary study guided by a developmental, ecological perspective, and designed to consider the physical, social, and psychological effects of childhood maltreatment through the transition from childhood to adolescence. Four waves of data collection have been completed, ranging from early (Mean age = 10.95) to late adolescence (Mean age = 18.24). Members of the maltreated group (n = 303) were selected from new cases that had been opened by the Department of Child and Family Services, whereas the comparison group (n = 151) were not involved with child welfare but lived in the same neighborhoods as the maltreated group. The study assessed a wide variety of domains including physical development (e.g., height, weight, body mass, pubertal development); physiological reactivity (e.g., cortisol); cognitive abilities; mental health (e.g., symptoms of depression, anxiety, trauma, and aggression); risk behavior (e.g., sexual activity, delinquency, or substance use); social development (e.g., self-esteem, competence, and social support); family environment; and exposure to community violence. Overall, our findings demonstrated the pervasive and persistent adverse effects of child maltreatment both within and across domains, but they also identified maltreated youth with positive functioning. Our hope is that this work will help move us toward identifying targets for intervention to cultivate resilience and positive adaptation after early maltreatment experiences. En ligne : http://dx.doi.org/10.1017/s0954579419001391 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] The Young Adolescent Project: A longitudinal study of the effects of maltreatment on adolescent development [Texte imprimé et/ou numérique] / Sonya NEGRIFF, Auteur ; Elana B. GORDIS, Auteur ; Elizabeth J. SUSMAN, Auteur ; Kihyun KIM, Auteur ; Melissa K. PECKINS, Auteur ; Janet U. SCHNEIDERMAN, Auteur ; Ferol E. MENNEN, Auteur . - p.1440-1459. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1440-1459 Mots-clés : adolescence  child maltreatment  longitudinal study Index. décimale : PER Périodiques Résumé : The Young Adolescent Project (YAP) is an ongoing longitudinal study investigating the effects of abuse and neglect on adolescent development. It is a multidisciplinary study guided by a developmental, ecological perspective, and designed to consider the physical, social, and psychological effects of childhood maltreatment through the transition from childhood to adolescence. Four waves of data collection have been completed, ranging from early (Mean age = 10.95) to late adolescence (Mean age = 18.24). Members of the maltreated group (n = 303) were selected from new cases that had been opened by the Department of Child and Family Services, whereas the comparison group (n = 151) were not involved with child welfare but lived in the same neighborhoods as the maltreated group. The study assessed a wide variety of domains including physical development (e.g., height, weight, body mass, pubertal development); physiological reactivity (e.g., cortisol); cognitive abilities; mental health (e.g., symptoms of depression, anxiety, trauma, and aggression); risk behavior (e.g., sexual activity, delinquency, or substance use); social development (e.g., self-esteem, competence, and social support); family environment; and exposure to community violence. Overall, our findings demonstrated the pervasive and persistent adverse effects of child maltreatment both within and across domains, but they also identified maltreated youth with positive functioning. Our hope is that this work will help move us toward identifying targets for intervention to cultivate resilience and positive adaptation after early maltreatment experiences. En ligne : http://dx.doi.org/10.1017/s0954579419001391 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Early experiences of insensitive caregiving and children's self-regulation: Vagal tone as a differential susceptibility factor / Michael A. SKIBO in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1460-1472 Titre : Early experiences of insensitive caregiving and children's self-regulation: Vagal tone as a differential susceptibility factor Type de document : Texte imprimé et/ou numérique Auteurs : Michael A. SKIBO, Auteur ; Melissa L. STURGE-APPLE, Auteur ; Jennifer H. SUOR, Auteur Article en page(s) : p.1460-1472 Langues : Anglais (eng) Mots-clés : differential susceptibility  parenting  respiratory sinus arrhythmia  self-regulation Index. décimale : PER Périodiques Résumé : A considerable body of research has linked parenting to the development of children's self-regulation. However, few studies have considered different domains of self-regulation, the effects of early caregiving behaviors, and whether or not parenting influences children equally. Towards this, the present investigation tested how early maternal insensitivity was associated with difficulties in children's effortful control in early childhood and their regulation of negative emotions during the early school years. Further, we tested whether children's resting vagal tone may operate as a susceptibility factor, consistent with differential susceptibility models. The sample included 220 pairs of mothers and their children who were assessed at 18 months, 3.5 years and 5 years of age. Laboratory visits consisted of observational paradigms and survey assessments. Early maternal insensitivity at 18 months of age forecasted difficulties with effortful control at age 3.5. Moreover, effortful control at age 3.5 was associated with greater anger, but not sadness, regulation at age 5. Consistent with differential susceptibility, children's resting vagal tone at 18 months of age moderated the role of early caregiving on children's effortful control. The findings suggest that low resting vagal tone may operate as a differential susceptibility factor in process models testing associations between early caregiving environments and children's self-regulation. En ligne : http://dx.doi.org/10.1017/s0954579419001408 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Early experiences of insensitive caregiving and children's self-regulation: Vagal tone as a differential susceptibility factor [Texte imprimé et/ou numérique] / Michael A. SKIBO, Auteur ; Melissa L. STURGE-APPLE, Auteur ; Jennifer H. SUOR, Auteur . - p.1460-1472. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1460-1472 Mots-clés : differential susceptibility  parenting  respiratory sinus arrhythmia  self-regulation Index. décimale : PER Périodiques Résumé : A considerable body of research has linked parenting to the development of children's self-regulation. However, few studies have considered different domains of self-regulation, the effects of early caregiving behaviors, and whether or not parenting influences children equally. Towards this, the present investigation tested how early maternal insensitivity was associated with difficulties in children's effortful control in early childhood and their regulation of negative emotions during the early school years. Further, we tested whether children's resting vagal tone may operate as a susceptibility factor, consistent with differential susceptibility models. The sample included 220 pairs of mothers and their children who were assessed at 18 months, 3.5 years and 5 years of age. Laboratory visits consisted of observational paradigms and survey assessments. Early maternal insensitivity at 18 months of age forecasted difficulties with effortful control at age 3.5. Moreover, effortful control at age 3.5 was associated with greater anger, but not sadness, regulation at age 5. Consistent with differential susceptibility, children's resting vagal tone at 18 months of age moderated the role of early caregiving on children's effortful control. The findings suggest that low resting vagal tone may operate as a differential susceptibility factor in process models testing associations between early caregiving environments and children's self-regulation. En ligne : http://dx.doi.org/10.1017/s0954579419001408 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Does puberty affect the development of behavior problems as a mediator, moderator, or unique predictor? / Adriene M. BELTZ in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1473-1485 Titre : Does puberty affect the development of behavior problems as a mediator, moderator, or unique predictor? Type de document : Texte imprimé et/ou numérique Auteurs : Adriene M. BELTZ, Auteur ; Robin P. CORLEY, Auteur ; Sally J. WADSWORTH, Auteur ; Lisabeth F. DILALLA, Auteur ; Sheri A. BERENBAUM, Auteur Article en page(s) : p.1473-1485 Langues : Anglais (eng) Mots-clés : adolescent development  externalizing behavior problems  internalizing behavior problems  pubertal timing Index. décimale : PER Périodiques Résumé : Pubertal timing matters for psychological development. Early maturation in girls is linked to risk for depression and externalizing problems in adolescence and possibly adulthood, and early and late maturation in boys are linked to depression. It is unclear whether pubertal timing uniquely predicts problems; it might instead mediate the continuity of behavior problems from childhood to adolescence or create psychological risk specifically in youth with existing problems, thus moderating the link. We investigated these issues in 534 girls and 550 boys, measuring pubertal timing by a logistic model fit to annual self-report measures of development and, in girls, age at menarche. Prepuberty internalizing and externalizing behavior problems were reported by parents. Adolescent behavior problems were reported by parents and youth. As expected, behavior problems were moderately stable. Pubertal timing was not predicted by childhood problems, so it did not mediate the continuity of behavior problems from childhood to adolescence. Pubertal timing did not moderate links between early and later problems for girls. For boys, early maturation accentuated the link between childhood problems and adolescent substance use. Overall, the replicated links between puberty and behavior problems appear to reflect the unique effects of puberty and child behavior problems on the development of adolescent behavior problems. En ligne : http://dx.doi.org/10.1017/s095457941900141x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Does puberty affect the development of behavior problems as a mediator, moderator, or unique predictor? [Texte imprimé et/ou numérique] / Adriene M. BELTZ, Auteur ; Robin P. CORLEY, Auteur ; Sally J. WADSWORTH, Auteur ; Lisabeth F. DILALLA, Auteur ; Sheri A. BERENBAUM, Auteur . - p.1473-1485. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1473-1485 Mots-clés : adolescent development  externalizing behavior problems  internalizing behavior problems  pubertal timing Index. décimale : PER Périodiques Résumé : Pubertal timing matters for psychological development. Early maturation in girls is linked to risk for depression and externalizing problems in adolescence and possibly adulthood, and early and late maturation in boys are linked to depression. It is unclear whether pubertal timing uniquely predicts problems; it might instead mediate the continuity of behavior problems from childhood to adolescence or create psychological risk specifically in youth with existing problems, thus moderating the link. We investigated these issues in 534 girls and 550 boys, measuring pubertal timing by a logistic model fit to annual self-report measures of development and, in girls, age at menarche. Prepuberty internalizing and externalizing behavior problems were reported by parents. Adolescent behavior problems were reported by parents and youth. As expected, behavior problems were moderately stable. Pubertal timing was not predicted by childhood problems, so it did not mediate the continuity of behavior problems from childhood to adolescence. Pubertal timing did not moderate links between early and later problems for girls. For boys, early maturation accentuated the link between childhood problems and adolescent substance use. Overall, the replicated links between puberty and behavior problems appear to reflect the unique effects of puberty and child behavior problems on the development of adolescent behavior problems. En ligne : http://dx.doi.org/10.1017/s095457941900141x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Preliminary indications that the Attachment and Biobehavioral Catch-up Intervention alters DNA methylation in maltreated children / Julie R. HOYE in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1486-1494 Titre : Preliminary indications that the Attachment and Biobehavioral Catch-up Intervention alters DNA methylation in maltreated children Type de document : Texte imprimé et/ou numérique Auteurs : Julie R. HOYE, Auteur ; David CHEISHVILI, Auteur ; Heather A. YARGER, Auteur ; Tania L. ROTH, Auteur ; Moshe SZYF, Auteur ; Mary DOZIER, Auteur Article en page(s) : p.1486-1494 Langues : Anglais (eng) Mots-clés : DNA methylation  epigenetics  intervention  maltreatment  parenting Index. décimale : PER Périodiques Résumé : Maltreatment during development is associated with epigenetic changes to the genome. Enhancing caregiving may mitigate these effects. Attachment and Biobehavioral Catch-Up (ABC) is an intervention that has been shown to improve parent-child relationships and a variety of biological and behavioral outcomes among children that are involved in Child Protective Services. This preliminary study, using a small sample size, explored whether children who received ABC exhibit different methylation patterns than those who received a control intervention. The participants included 23 children aged 6-21 months who were randomized to receive ABC (n = 12) or a control intervention (n = 11). While the children displayed similar methylation patterns preintervention, DNA methylation varied between the ABC and control groups at 14,828 sites postintervention. Functional pathway analyses indicated that these differences were associated with gene pathways that are involved in cell signaling, metabolism, and neuronal development. This study is one of the first to explore parenting intervention effects on children's DNA methylation at the whole genome level in infancy. These preliminary findings provide a basis for hypothesis generation in further research with larger-scale studies regarding the malleability of epigenetic states that are associated with maltreatment. En ligne : http://dx.doi.org/10.1017/s0954579419001421 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Preliminary indications that the Attachment and Biobehavioral Catch-up Intervention alters DNA methylation in maltreated children [Texte imprimé et/ou numérique] / Julie R. HOYE, Auteur ; David CHEISHVILI, Auteur ; Heather A. YARGER, Auteur ; Tania L. ROTH, Auteur ; Moshe SZYF, Auteur ; Mary DOZIER, Auteur . - p.1486-1494. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1486-1494 Mots-clés : DNA methylation  epigenetics  intervention  maltreatment  parenting Index. décimale : PER Périodiques Résumé : Maltreatment during development is associated with epigenetic changes to the genome. Enhancing caregiving may mitigate these effects. Attachment and Biobehavioral Catch-Up (ABC) is an intervention that has been shown to improve parent-child relationships and a variety of biological and behavioral outcomes among children that are involved in Child Protective Services. This preliminary study, using a small sample size, explored whether children who received ABC exhibit different methylation patterns than those who received a control intervention. The participants included 23 children aged 6-21 months who were randomized to receive ABC (n = 12) or a control intervention (n = 11). While the children displayed similar methylation patterns preintervention, DNA methylation varied between the ABC and control groups at 14,828 sites postintervention. Functional pathway analyses indicated that these differences were associated with gene pathways that are involved in cell signaling, metabolism, and neuronal development. This study is one of the first to explore parenting intervention effects on children's DNA methylation at the whole genome level in infancy. These preliminary findings provide a basis for hypothesis generation in further research with larger-scale studies regarding the malleability of epigenetic states that are associated with maltreatment. En ligne : http://dx.doi.org/10.1017/s0954579419001421 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Hungry for inclusion: Exposure to peer victimization and heightened social monitoring in adolescent girls / Eva H. TELZER in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1495-1508 Titre : Hungry for inclusion: Exposure to peer victimization and heightened social monitoring in adolescent girls Type de document : Texte imprimé et/ou numérique Auteurs : Eva H. TELZER, Auteur ; Carina H. FOWLER, Auteur ; Megan M. DAVIS, Auteur ; Karen D. RUDOLPH, Auteur Article en page(s) : p.1495-1508 Langues : Anglais (eng) Mots-clés : adolescence  fMRI  peer victimization  social monitoring Index. décimale : PER Périodiques Résumé : Belonging to a social group is one of the most important factors contributing to well-being. The Belonging Regulation model proposes that humans possess a social monitoring system (SMS) that evaluates social inclusion and monitors belonging needs. Here, we used a prospective longitudinal design to examine links between peer victimization experienced across 7 years and social monitoring at the behavioral and neural level in adolescent girls (n = 38, Mage = 15.43 years, SD = .33). Participants completed a social evaluation task during a functional magnetic resonance imaging (fMRI) scan. More severe peer victimization was associated with increased activation to in-group versus out-group peers in the amygdala, ventral striatum, fusiform gyrus, and temporoparietal junction. Moreover, participants who displayed increased activation in these regions reported lower social self esteem and higher levels of internalizing and externalizing symptoms. These results suggest that exposure to peer victimization across the school years is associated with heightened social monitoring at the neural level during adolescence, which has potential adverse implications for girls' adjustment and well-being. En ligne : http://dx.doi.org/10.1017/s0954579419001433 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Hungry for inclusion: Exposure to peer victimization and heightened social monitoring in adolescent girls [Texte imprimé et/ou numérique] / Eva H. TELZER, Auteur ; Carina H. FOWLER, Auteur ; Megan M. DAVIS, Auteur ; Karen D. RUDOLPH, Auteur . - p.1495-1508. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1495-1508 Mots-clés : adolescence  fMRI  peer victimization  social monitoring Index. décimale : PER Périodiques Résumé : Belonging to a social group is one of the most important factors contributing to well-being. The Belonging Regulation model proposes that humans possess a social monitoring system (SMS) that evaluates social inclusion and monitors belonging needs. Here, we used a prospective longitudinal design to examine links between peer victimization experienced across 7 years and social monitoring at the behavioral and neural level in adolescent girls (n = 38, Mage = 15.43 years, SD = .33). Participants completed a social evaluation task during a functional magnetic resonance imaging (fMRI) scan. More severe peer victimization was associated with increased activation to in-group versus out-group peers in the amygdala, ventral striatum, fusiform gyrus, and temporoparietal junction. Moreover, participants who displayed increased activation in these regions reported lower social self esteem and higher levels of internalizing and externalizing symptoms. These results suggest that exposure to peer victimization across the school years is associated with heightened social monitoring at the neural level during adolescence, which has potential adverse implications for girls' adjustment and well-being. En ligne : http://dx.doi.org/10.1017/s0954579419001433 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Maternal alcohol dependence and harsh caregiving across parenting contexts: The moderating role of child negative emotionality / Debrielle T. JACQUES in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1509-1523 Titre : Maternal alcohol dependence and harsh caregiving across parenting contexts: The moderating role of child negative emotionality Type de document : Texte imprimé et/ou numérique Auteurs : Debrielle T. JACQUES, Auteur ; Melissa L. STURGE-APPLE, Auteur ; Patrick T. DAVIES, Auteur ; Dante CICCHETTI, Auteur Article en page(s) : p.1509-1523 Langues : Anglais (eng) Mots-clés : child temperament  harsh parenting  maternal alcohol dependence  maternal psychopathology  maternal substence abuse  negative emotionality Index. décimale : PER Périodiques Résumé : Parental alcohol dependence is a significant risk factor for harsh caregiving behaviors; however, it is unknown whether and how harsh caregiving changes over time and across parenting contexts for alcohol-dependent mothers. Furthermore, to our knowledge, no studies have examined whether and how distinct dimensions of child characteristics, such as negative emotionality modulate harsh caregiving among alcohol-dependent mothers. Guided by parenting process models, the present study examined how two distinct domains of children's negative emotionality-fear and frustration-moderate the association between maternal alcohol dependence and maternal harshness across discipline and free-play contexts. A high-risk sample of 201 mothers and their two-year-old children were studied over a one-year period. Results from latent difference score analyses indicated that harsh parenting among alcohol-dependent mothers increased over time in the more stressful discipline context, but not in the parent-child play context. This effect was maintained even after controlling for other parenting risk factors, including other forms of maternal psychopathology. Furthermore, this increase in harsh parenting was specific to alcohol-dependent mothers whose children were displaying high levels of anger and frustration. Findings provide support for specificity in conceptualizations of child negative emotionality and parenting contexts as potential determinants of maladaptive caregiving among alcohol-dependent mothers. En ligne : http://dx.doi.org/10.1017/s0954579419001445 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Maternal alcohol dependence and harsh caregiving across parenting contexts: The moderating role of child negative emotionality [Texte imprimé et/ou numérique] / Debrielle T. JACQUES, Auteur ; Melissa L. STURGE-APPLE, Auteur ; Patrick T. DAVIES, Auteur ; Dante CICCHETTI, Auteur . - p.1509-1523. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1509-1523 Mots-clés : child temperament  harsh parenting  maternal alcohol dependence  maternal psychopathology  maternal substence abuse  negative emotionality Index. décimale : PER Périodiques Résumé : Parental alcohol dependence is a significant risk factor for harsh caregiving behaviors; however, it is unknown whether and how harsh caregiving changes over time and across parenting contexts for alcohol-dependent mothers. Furthermore, to our knowledge, no studies have examined whether and how distinct dimensions of child characteristics, such as negative emotionality modulate harsh caregiving among alcohol-dependent mothers. Guided by parenting process models, the present study examined how two distinct domains of children's negative emotionality-fear and frustration-moderate the association between maternal alcohol dependence and maternal harshness across discipline and free-play contexts. A high-risk sample of 201 mothers and their two-year-old children were studied over a one-year period. Results from latent difference score analyses indicated that harsh parenting among alcohol-dependent mothers increased over time in the more stressful discipline context, but not in the parent-child play context. This effect was maintained even after controlling for other parenting risk factors, including other forms of maternal psychopathology. Furthermore, this increase in harsh parenting was specific to alcohol-dependent mothers whose children were displaying high levels of anger and frustration. Findings provide support for specificity in conceptualizations of child negative emotionality and parenting contexts as potential determinants of maladaptive caregiving among alcohol-dependent mothers. En ligne : http://dx.doi.org/10.1017/s0954579419001445 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

A Comparison of the effects of preterm birth and institutional deprivation on child temperament / Lucia Miranda REYES in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1524-1533 Titre : A Comparison of the effects of preterm birth and institutional deprivation on child temperament Type de document : Texte imprimé et/ou numérique Auteurs : Lucia Miranda REYES, Auteur ; Julia JAEKEL, Auteur ; Jana KREPPNER, Auteur ; Dieter WOLKE, Auteur ; Edmund J. S. SONUGA-BARKE, Auteur Article en page(s) : p.1524-1533 Langues : Anglais (eng) Mots-clés : behavior regulation  early adversity  institutional deprivation  preterm birth Index. décimale : PER Périodiques Résumé : Both preterm birth and early institutional deprivation are associated with neurodevelopmental impairment-with both shared and distinctive features. To explore shared underlying mechanisms, this study directly compared the effects of these putative risk factors on temperament profiles in six-year-olds: Children born very preterm (<32 weeks gestation) or at very low birthweight (<1500 g) from the Bavarian Longitudinal Study (n = 299); and children who experienced >6 months of deprivation in Romanian institutions from the English and Romanian Adoptees Study (n = 101). The former were compared with 311 healthy term born controls and the latter with 52 nondeprived adoptees. At 6 years, temperament was assessed via parent reports across 5 dimensions: effortful control, activity, shyness, emotionality, and sociability. Very preterm/very low birthweight and postinstitutionalized children showed similarly aberrant profiles in terms of lower effortful control, preterm = -0.50, 95% CI [-0.67, -0.33]; postinstitutionalized = -0.48, 95% CI [-0.82, -0.14], compared with their respective controls. Additionally, postinstitutionalized children showed higher activity, whereas very preterm/very low birthweight children showed lower shyness. Preterm birth and early institutionalization are similarly associated with poorer effortful control, which might contribute to long-term vulnerability. More research is needed to examine temperamental processes as common mediators of negative long-term outcomes following early adversity. En ligne : http://dx.doi.org/10.1017/s0954579419001457 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] A Comparison of the effects of preterm birth and institutional deprivation on child temperament [Texte imprimé et/ou numérique] / Lucia Miranda REYES, Auteur ; Julia JAEKEL, Auteur ; Jana KREPPNER, Auteur ; Dieter WOLKE, Auteur ; Edmund J. S. SONUGA-BARKE, Auteur . - p.1524-1533. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1524-1533 Mots-clés : behavior regulation  early adversity  institutional deprivation  preterm birth Index. décimale : PER Périodiques Résumé : Both preterm birth and early institutional deprivation are associated with neurodevelopmental impairment-with both shared and distinctive features. To explore shared underlying mechanisms, this study directly compared the effects of these putative risk factors on temperament profiles in six-year-olds: Children born very preterm (<32 weeks gestation) or at very low birthweight (<1500 g) from the Bavarian Longitudinal Study (n = 299); and children who experienced >6 months of deprivation in Romanian institutions from the English and Romanian Adoptees Study (n = 101). The former were compared with 311 healthy term born controls and the latter with 52 nondeprived adoptees. At 6 years, temperament was assessed via parent reports across 5 dimensions: effortful control, activity, shyness, emotionality, and sociability. Very preterm/very low birthweight and postinstitutionalized children showed similarly aberrant profiles in terms of lower effortful control, preterm = -0.50, 95% CI [-0.67, -0.33]; postinstitutionalized = -0.48, 95% CI [-0.82, -0.14], compared with their respective controls. Additionally, postinstitutionalized children showed higher activity, whereas very preterm/very low birthweight children showed lower shyness. Preterm birth and early institutionalization are similarly associated with poorer effortful control, which might contribute to long-term vulnerability. More research is needed to examine temperamental processes as common mediators of negative long-term outcomes following early adversity. En ligne : http://dx.doi.org/10.1017/s0954579419001457 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Neglectful maternal caregiving involves altered brain volume in empathy-related areas / María José RODRIGO in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1534-1543 Titre : Neglectful maternal caregiving involves altered brain volume in empathy-related areas Type de document : Texte imprimé et/ou numérique Auteurs : María José RODRIGO, Auteur ; Inmaculada LEON, Auteur ; Lorna GARCÍA-PENTÓN, Auteur ; Juan Andrés HERNÁNDEZ-CABRERA, Auteur ; Ileana QUINONES, Auteur Article en page(s) : p.1534-1543 Langues : Anglais (eng) Mots-clés : empathy  maternal neglect  mother–child interaction  volume alterations  voxel-based morphometry Index. décimale : PER Périodiques Résumé : The maternal brain undergoes adaptations to sensitive caregiving that are critical for infant well-being. We investigated structural alterations associated with neglectful caregiving and their effects on mother-child interactive behavior. High-resolution 3D volumetric images were obtained on 25 neglectful (NM) and 23 non-neglectful control (CM) mothers. Using voxel-based morphometry, we compared differences in gray and white matter (GM and WM, respectively) volume. Mothers completed an empathy scale and participated with their children in a play task (Emotional Availability Scale, EA). Neglectful mothers showed smaller GM volume in the right insula, anterior/middle cingulate (ACC/MCC), and right inferior frontal gyrus and less WM volume in bilateral frontal regions than did CM. A greater GM volume was observed in the right fusiform and cerebellum in NM than in CM. Regression analyses showed a negative effect of greater fusiform GM volume and a positive effect of greater right frontal WM volume on EA. Mediation analyses showed the role of emotional empathy in the positive effect of the insula and right inferior frontal gyrus and in the negative effect of the cerebellum on EA. Neglectful mothering involves alterations in emotional empathy-related areas and in frontal areas associated with poor mother-child interactive bonding, indicating how critical these areas are for sensitive caregiving. En ligne : http://dx.doi.org/10.1017/s0954579419001469 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Neglectful maternal caregiving involves altered brain volume in empathy-related areas [Texte imprimé et/ou numérique] / María José RODRIGO, Auteur ; Inmaculada LEON, Auteur ; Lorna GARCÍA-PENTÓN, Auteur ; Juan Andrés HERNÁNDEZ-CABRERA, Auteur ; Ileana QUINONES, Auteur . - p.1534-1543. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1534-1543 Mots-clés : empathy  maternal neglect  mother–child interaction  volume alterations  voxel-based morphometry Index. décimale : PER Périodiques Résumé : The maternal brain undergoes adaptations to sensitive caregiving that are critical for infant well-being. We investigated structural alterations associated with neglectful caregiving and their effects on mother-child interactive behavior. High-resolution 3D volumetric images were obtained on 25 neglectful (NM) and 23 non-neglectful control (CM) mothers. Using voxel-based morphometry, we compared differences in gray and white matter (GM and WM, respectively) volume. Mothers completed an empathy scale and participated with their children in a play task (Emotional Availability Scale, EA). Neglectful mothers showed smaller GM volume in the right insula, anterior/middle cingulate (ACC/MCC), and right inferior frontal gyrus and less WM volume in bilateral frontal regions than did CM. A greater GM volume was observed in the right fusiform and cerebellum in NM than in CM. Regression analyses showed a negative effect of greater fusiform GM volume and a positive effect of greater right frontal WM volume on EA. Mediation analyses showed the role of emotional empathy in the positive effect of the insula and right inferior frontal gyrus and in the negative effect of the cerebellum on EA. Neglectful mothering involves alterations in emotional empathy-related areas and in frontal areas associated with poor mother-child interactive bonding, indicating how critical these areas are for sensitive caregiving. En ligne : http://dx.doi.org/10.1017/s0954579419001469 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

The long-term indirect effect of the early Family Check-Up intervention on adolescent internalizing and externalizing symptoms via inhibitory control / Rochelle F. HENTGES in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1544-1554 Titre : The long-term indirect effect of the early Family Check-Up intervention on adolescent internalizing and externalizing symptoms via inhibitory control Type de document : Texte imprimé et/ou numérique Auteurs : Rochelle F. HENTGES, Auteur ; Chelsea M. WEAVER KRUG, Auteur ; Daniel S. SHAW, Auteur ; Melvin N. WILSON, Auteur ; Thomas J. DISHION, Auteur ; Kathryn LEMERY-CHALFANT, Auteur Article en page(s) : p.1544-1554 Langues : Anglais (eng) Mots-clés : externalizing  inhibitory control  internalizing  intervention  longitudinal effects Index. décimale : PER Périodiques Résumé : This study examined the long-term effects of a randomized controlled trial of the Family Check-Up (FCU) intervention initiated at age 2 on inhibitory control in middle childhood and adolescent internalizing and externalizing problems. We hypothesized that the FCU would promote higher inhibitory control in middle childhood relative to the control group, which in turn would be associated with lower internalizing and externalizing symptomology at age 14. Participants were 731 families, with half (n = 367) of the families assigned to the FCU intervention. Using an intent-to-treat design, results indicate that the FCU intervention was indirectly associated with both lower internalizing and externalizing symptoms at age 14 via its effect on increased inhibitory control in middle childhood (i.e., ages 8.5-10.5). Findings highlight the potential for interventions initiated in toddlerhood to have long-term impacts on self-regulation processes, which can further reduce the risk for behavioral and emotional difficulties in adolescence. En ligne : http://dx.doi.org/10.1017/s0954579419001482 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] The long-term indirect effect of the early Family Check-Up intervention on adolescent internalizing and externalizing symptoms via inhibitory control [Texte imprimé et/ou numérique] / Rochelle F. HENTGES, Auteur ; Chelsea M. WEAVER KRUG, Auteur ; Daniel S. SHAW, Auteur ; Melvin N. WILSON, Auteur ; Thomas J. DISHION, Auteur ; Kathryn LEMERY-CHALFANT, Auteur . - p.1544-1554. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1544-1554 Mots-clés : externalizing  inhibitory control  internalizing  intervention  longitudinal effects Index. décimale : PER Périodiques Résumé : This study examined the long-term effects of a randomized controlled trial of the Family Check-Up (FCU) intervention initiated at age 2 on inhibitory control in middle childhood and adolescent internalizing and externalizing problems. We hypothesized that the FCU would promote higher inhibitory control in middle childhood relative to the control group, which in turn would be associated with lower internalizing and externalizing symptomology at age 14. Participants were 731 families, with half (n = 367) of the families assigned to the FCU intervention. Using an intent-to-treat design, results indicate that the FCU intervention was indirectly associated with both lower internalizing and externalizing symptoms at age 14 via its effect on increased inhibitory control in middle childhood (i.e., ages 8.5-10.5). Findings highlight the potential for interventions initiated in toddlerhood to have long-term impacts on self-regulation processes, which can further reduce the risk for behavioral and emotional difficulties in adolescence. En ligne : http://dx.doi.org/10.1017/s0954579419001482 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433