Dépouillements

Substantial elevation of telomeric oxidized bases in childhood autism / Mohammad EFTEKHAR in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102496 Titre : Substantial elevation of telomeric oxidized bases in childhood autism Type de document : Texte imprimé et/ou numérique Auteurs : Mohammad EFTEKHAR, Auteur ; Yasin PANAHI, Auteur ; Fahimeh Salasar MOGHADDAM, Auteur ; Mohammad Reza ESKANDARI, Auteur ; Hamid PEZESHK, Auteur ; Mehrdad PEDRAM, Auteur Article en page(s) : p.102496 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Sex bias  Telomeres  Relative telomere length  Oxidized Bases  Etiology  Biomarker Index. décimale : PER Périodiques Résumé : Background The underlying molecular mechanisms responsible for the etiology of autism and its sex-biased prevalence remain largely elusive. We have previously shown that children with non-syndromic low-functioning idiopathic autism exhibit a sexually dimorphic pattern of relative telomere length (RTL), with autistic male children having significantly shorter RTL than autistic female children, healthy controls, and paired siblings. By contrast, a number of autistic girls had longer RTLs than healthy controls. Here, we investigated levels of telomeric oxidized base (TelOB) lesions among the same study subjects and groups. Methods Employing a quantitative PCR (qPCR)-based method, which combines DNA digestion targeting oxidized bases and telomere measurement, TelOB lesions were measured using genomic DNA extracted from saliva samples collected from 24 children (14 male and 10 female) with autism, 10 paired siblings, and 24 sex, age, and location-matched typically-developing controls. Results Our findings show that both male and female autistic children exhibit substantially higher TelOB lesions at their telomeres than healthy controls and paired siblings. Interestingly, these elevated levels of TelOBs show a direct correlation with RTL values in autistic children but not in healthy controls. However, TelOB levels do not show any association with age either in the autistic children or the healthy control group. Conclusions Our findings open a fresh angle into autism spectrum disorders (ASD), raise new questions, and lay the foundation for further research into telomere biology and underlying molecular mechanisms involved in ASD. TelOB levels are likely set during early development and may serve as biomarkers for childhood autism. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102496 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] Substantial elevation of telomeric oxidized bases in childhood autism [Texte imprimé et/ou numérique] / Mohammad EFTEKHAR, Auteur ; Yasin PANAHI, Auteur ; Fahimeh Salasar MOGHADDAM, Auteur ; Mohammad Reza ESKANDARI, Auteur ; Hamid PEZESHK, Auteur ; Mehrdad PEDRAM, Auteur . - p.102496. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102496 Mots-clés : Autism spectrum disorders  Sex bias  Telomeres  Relative telomere length  Oxidized Bases  Etiology  Biomarker Index. décimale : PER Périodiques Résumé : Background The underlying molecular mechanisms responsible for the etiology of autism and its sex-biased prevalence remain largely elusive. We have previously shown that children with non-syndromic low-functioning idiopathic autism exhibit a sexually dimorphic pattern of relative telomere length (RTL), with autistic male children having significantly shorter RTL than autistic female children, healthy controls, and paired siblings. By contrast, a number of autistic girls had longer RTLs than healthy controls. Here, we investigated levels of telomeric oxidized base (TelOB) lesions among the same study subjects and groups. Methods Employing a quantitative PCR (qPCR)-based method, which combines DNA digestion targeting oxidized bases and telomere measurement, TelOB lesions were measured using genomic DNA extracted from saliva samples collected from 24 children (14 male and 10 female) with autism, 10 paired siblings, and 24 sex, age, and location-matched typically-developing controls. Results Our findings show that both male and female autistic children exhibit substantially higher TelOB lesions at their telomeres than healthy controls and paired siblings. Interestingly, these elevated levels of TelOBs show a direct correlation with RTL values in autistic children but not in healthy controls. However, TelOB levels do not show any association with age either in the autistic children or the healthy control group. Conclusions Our findings open a fresh angle into autism spectrum disorders (ASD), raise new questions, and lay the foundation for further research into telomere biology and underlying molecular mechanisms involved in ASD. TelOB levels are likely set during early development and may serve as biomarkers for childhood autism. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102496 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

Measurement invariance of the Child Behavior Checklist in autistic toddlers / Tara L. BENNINGER in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102500 Titre : Measurement invariance of the Child Behavior Checklist in autistic toddlers Type de document : Texte imprimé et/ou numérique Auteurs : Tara L. BENNINGER, Auteur ; Megan NORRIS, Auteur ; Andrea N. WITWER, Auteur Article en page(s) : p.102500 Langues : Anglais (eng) Mots-clés : Factor analysis  Measurement invariance  Child behavior checklist  Challenging behavior  Autism spectrum disorder  Toddlers Index. décimale : PER Périodiques Résumé : Background Challenging behavior has been examined in older children and adolescents with autism spectrum disorder (ASD), but less is known about these behaviors in toddlers, due in part to variability in measurement and limited instruments available for this population. To address this need, this study examined the psychometric properties of the Child Behavior Checklist (CBCL), a commonly used and widely validated measure of challenging behavior, in a group of toddlers with ASD. Method Participants included 496 toddlers aged 18-48 months with (n=398) and without (n= 100) a diagnosis of ASD. Psychometrics of the CBCL were analyzed including internal consistency, factor structure, and measurement invariance. Results Confirmatory factor analysis results indicated acceptable fit for the tested model, and internal consistency was largely acceptable. All levels of measurement invariance were tested for each subscale. The Emotional Reactivity, Anxious/Depressed, Withdrawn, and Aggressive Behavior subscales achieved scalar invariance, while the Attention Problems subscale achieved metric invariance, and the Somatic Complaints subscale did not achieve even configural invariance. Conclusions Results indicate the current CBCL conceptualization of challenging behavior in autistic toddlers is consistent with such constructs in older autistic children and provide preliminary support for the use of the CBCL to assess for challenging behavior in toddlers with ASD. Measurement invariance (MI) analyses support the construct validity of the CBCL in toddlers with ASD. However, based on the results of the MI analyses, some caution is warranted with specific subscales when conducting group comparison analyses between toddlers with and without ASD. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102500 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] Measurement invariance of the Child Behavior Checklist in autistic toddlers [Texte imprimé et/ou numérique] / Tara L. BENNINGER, Auteur ; Megan NORRIS, Auteur ; Andrea N. WITWER, Auteur . - p.102500. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102500 Mots-clés : Factor analysis  Measurement invariance  Child behavior checklist  Challenging behavior  Autism spectrum disorder  Toddlers Index. décimale : PER Périodiques Résumé : Background Challenging behavior has been examined in older children and adolescents with autism spectrum disorder (ASD), but less is known about these behaviors in toddlers, due in part to variability in measurement and limited instruments available for this population. To address this need, this study examined the psychometric properties of the Child Behavior Checklist (CBCL), a commonly used and widely validated measure of challenging behavior, in a group of toddlers with ASD. Method Participants included 496 toddlers aged 18-48 months with (n=398) and without (n= 100) a diagnosis of ASD. Psychometrics of the CBCL were analyzed including internal consistency, factor structure, and measurement invariance. Results Confirmatory factor analysis results indicated acceptable fit for the tested model, and internal consistency was largely acceptable. All levels of measurement invariance were tested for each subscale. The Emotional Reactivity, Anxious/Depressed, Withdrawn, and Aggressive Behavior subscales achieved scalar invariance, while the Attention Problems subscale achieved metric invariance, and the Somatic Complaints subscale did not achieve even configural invariance. Conclusions Results indicate the current CBCL conceptualization of challenging behavior in autistic toddlers is consistent with such constructs in older autistic children and provide preliminary support for the use of the CBCL to assess for challenging behavior in toddlers with ASD. Measurement invariance (MI) analyses support the construct validity of the CBCL in toddlers with ASD. However, based on the results of the MI analyses, some caution is warranted with specific subscales when conducting group comparison analyses between toddlers with and without ASD. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102500 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

Effects of creative movement, general movement, or seated play interventions on motor performance in children with autism spectrum disorder: A pilot randomized controlled trial / W. C. SU in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102501 Titre : Effects of creative movement, general movement, or seated play interventions on motor performance in children with autism spectrum disorder: A pilot randomized controlled trial Type de document : Texte imprimé et/ou numérique Auteurs : W. C. SU, Auteur ; S. SRINIVASAN, Auteur ; A. N. BHAT, Auteur Article en page(s) : p.102501 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder  Creative Movement Intervention  Physical Activity  Sedentary Play  Gross Motor Coordination  Praxis Index. décimale : PER Périodiques Résumé : Background Children with ASD experience significant gross motor challenges that could be addressed using motor interventions. However, contemporary ASD interventions that are sedentary in nature often target communication and fine motor skills and not children?s gross motor difficulties. Methods In the current pilot RCT, we evaluated changes in various motor outcomes (i.e., gross/fine motor coordination, locomotor skills, functional endurance, and praxis/imitation performance) following two types of whole-body motor interventions (Creative Movement (CM) or General Movement (GM)) and compared them to a Sedentary Play (SP) intervention focused on improving fine motor skills in children with ASD. Forty-five children with ASD (Mean Age +SE: 8.7 + 0.3, 38 males) were randomly assigned to the CM, GM, or SP groups and received 8 weeks of group-specific training. Results Both CM and GM interventions led to medium-to-large improvements in gross motor performance, including improved body coordination, strength/agility, locomotor skills, and walking endurance. Children in the CM group additionally showed medium-to-large-sized improvements in praxis performance, while children in the SP group showed improvements in fine motor performance. These training-related improvements were supported by improvements reported via parental questionnaires. Conclusions Researchers and clinicians should incorporate whole-body interventions targeting gross motor skills in the plan of care for children with ASD. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102501 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] Effects of creative movement, general movement, or seated play interventions on motor performance in children with autism spectrum disorder: A pilot randomized controlled trial [Texte imprimé et/ou numérique] / W. C. SU, Auteur ; S. SRINIVASAN, Auteur ; A. N. BHAT, Auteur . - p.102501. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102501 Mots-clés : Autism Spectrum Disorder  Creative Movement Intervention  Physical Activity  Sedentary Play  Gross Motor Coordination  Praxis Index. décimale : PER Périodiques Résumé : Background Children with ASD experience significant gross motor challenges that could be addressed using motor interventions. However, contemporary ASD interventions that are sedentary in nature often target communication and fine motor skills and not children?s gross motor difficulties. Methods In the current pilot RCT, we evaluated changes in various motor outcomes (i.e., gross/fine motor coordination, locomotor skills, functional endurance, and praxis/imitation performance) following two types of whole-body motor interventions (Creative Movement (CM) or General Movement (GM)) and compared them to a Sedentary Play (SP) intervention focused on improving fine motor skills in children with ASD. Forty-five children with ASD (Mean Age +SE: 8.7 + 0.3, 38 males) were randomly assigned to the CM, GM, or SP groups and received 8 weeks of group-specific training. Results Both CM and GM interventions led to medium-to-large improvements in gross motor performance, including improved body coordination, strength/agility, locomotor skills, and walking endurance. Children in the CM group additionally showed medium-to-large-sized improvements in praxis performance, while children in the SP group showed improvements in fine motor performance. These training-related improvements were supported by improvements reported via parental questionnaires. Conclusions Researchers and clinicians should incorporate whole-body interventions targeting gross motor skills in the plan of care for children with ASD. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102501 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

The spectrum effect: Convergence of clinical and neuropsychological characteristics in adults referred for autism assessment / Federico Maria LARCHER in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102502 Titre : The spectrum effect: Convergence of clinical and neuropsychological characteristics in adults referred for autism assessment Type de document : Texte imprimé et/ou numérique Auteurs : Federico Maria LARCHER, Auteur ; Michael GRÖZINGER, Auteur Article en page(s) : p.102502 Langues : Anglais (eng) Mots-clés : Adult autism  AQ  Diagnostic assessment  Cognition  ER40  Neuropsychological profile  Real-world samples Index. décimale : PER Périodiques Résumé : Clinical and neuropsychological profiles of adults referred for autism assessment are not thoroughly understood, and information derived from studies comparing autistic adults to neurotypical controls might not be accurate to infer on individuals in a real-world, clinical setting. 263 adults (aged 18-65 years, 70?% males) referred to our clinic with a suspected diagnosis of autism were clinically explored and administered neuropsychological investigations. The suspected diagnosis was either confirmed or rejected. We conducted multivariate and post-hoc univariate analyses of covariance (MANCOVA; ANCOVA), controlling for possible confounders, to evaluate differences between autistic and non-autistic participants and further associations. Effect sizes (partial ?2) were calculated for significant results. There were no significant differences in age means and sex ratios. Both groups showed high Autism Questionnaire (AQ) scores, high schizoid, avoidant, and obsessive-compulsive scores, and mild depressive symptoms, without significant difference between groups. The effect sizes of differences ranged from negligible to small for measures of nonsocial cognition, but were large for a measure of social cognition, the emotion recognition 40 (ER40). Autistic and non-autistic participants present converging features across multiple measures. In this diagnostic setting, psychiatric and neuropsychological measures are helpful in identifying individual difficulties and strengths. However, most of them, including the AQ, are poor indicators of autism. Our results mostly aligned with previous research and showed that information derived from comparisons to neurotypical controls cannot be directly transferred to a real-world setting. Detected impairments in emotion recognition were fairly specific to autism, expanding on previous findings. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102502 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] The spectrum effect: Convergence of clinical and neuropsychological characteristics in adults referred for autism assessment [Texte imprimé et/ou numérique] / Federico Maria LARCHER, Auteur ; Michael GRÖZINGER, Auteur . - p.102502. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102502 Mots-clés : Adult autism  AQ  Diagnostic assessment  Cognition  ER40  Neuropsychological profile  Real-world samples Index. décimale : PER Périodiques Résumé : Clinical and neuropsychological profiles of adults referred for autism assessment are not thoroughly understood, and information derived from studies comparing autistic adults to neurotypical controls might not be accurate to infer on individuals in a real-world, clinical setting. 263 adults (aged 18-65 years, 70?% males) referred to our clinic with a suspected diagnosis of autism were clinically explored and administered neuropsychological investigations. The suspected diagnosis was either confirmed or rejected. We conducted multivariate and post-hoc univariate analyses of covariance (MANCOVA; ANCOVA), controlling for possible confounders, to evaluate differences between autistic and non-autistic participants and further associations. Effect sizes (partial ?2) were calculated for significant results. There were no significant differences in age means and sex ratios. Both groups showed high Autism Questionnaire (AQ) scores, high schizoid, avoidant, and obsessive-compulsive scores, and mild depressive symptoms, without significant difference between groups. The effect sizes of differences ranged from negligible to small for measures of nonsocial cognition, but were large for a measure of social cognition, the emotion recognition 40 (ER40). Autistic and non-autistic participants present converging features across multiple measures. In this diagnostic setting, psychiatric and neuropsychological measures are helpful in identifying individual difficulties and strengths. However, most of them, including the AQ, are poor indicators of autism. Our results mostly aligned with previous research and showed that information derived from comparisons to neurotypical controls cannot be directly transferred to a real-world setting. Detected impairments in emotion recognition were fairly specific to autism, expanding on previous findings. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102502 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

Higher levels of autistic traits in the general population are associated with reduced visual field asymmetries in a dual-stream attentional blink task / Jason L. RINGO in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102503 Titre : Higher levels of autistic traits in the general population are associated with reduced visual field asymmetries in a dual-stream attentional blink task Type de document : Texte imprimé et/ou numérique Auteurs : Jason L. RINGO, Auteur ; Lisa N. JEFFERIES, Auteur ; Jacob A. BURACK, Auteur Article en page(s) : p.102503 Langues : Anglais (eng) Mots-clés : Autistic traits  Broader autism phenotype  Perceptual load  Visual field  Lateralization  Spatial attention Index. décimale : PER Périodiques Résumé : Background Spatial attention is typically right-hemisphere lateralized, resulting in a bias to preferentially process information in the left visual field (VF). As atypical hemispheric lateralization is considered a fundamental neurobiological feature of autism, we assessed whether it is also evident in people who display higher levels of autistic-type traits but do not meet the criteria for a clinical diagnosis of autism. In doing so, we used a dual-stream attentional blink task - a task with heavy processing demands and stimuli displayed simultaneously in both VFs - to elicit inter-hemispheric competition and assess visual field asymmetries. Method The participants were 82 university students, who had never been clinically diagnosed with autism, divided into two groups based on the level of autistic traits that they displayed on the Autism Quotient scale (AQ; Baron-Cohen et al., 2001). Two simultaneous streams of digit-distractors were displayed, one in each VF, and the participants' task was to identify two letter-targets that were displayed unpredictably in the left or right stream. Results We found reduced VF asymmetries in higher autism-trait individuals, with the magnitude of the asymmetry correlating with AQ score. Conclusions We suggest that the reduced VF asymmetries in individuals with higher autism traits may be due to increased perceptual processing capacity (Remington et al., 2009), which reduces hemispheric competition and, thus, visual field asymmetries. The findings also highlight that even subtle differences in the degree of autistic traits in the general population may be associated with differences in visual attention. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102503 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] Higher levels of autistic traits in the general population are associated with reduced visual field asymmetries in a dual-stream attentional blink task [Texte imprimé et/ou numérique] / Jason L. RINGO, Auteur ; Lisa N. JEFFERIES, Auteur ; Jacob A. BURACK, Auteur . - p.102503. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102503 Mots-clés : Autistic traits  Broader autism phenotype  Perceptual load  Visual field  Lateralization  Spatial attention Index. décimale : PER Périodiques Résumé : Background Spatial attention is typically right-hemisphere lateralized, resulting in a bias to preferentially process information in the left visual field (VF). As atypical hemispheric lateralization is considered a fundamental neurobiological feature of autism, we assessed whether it is also evident in people who display higher levels of autistic-type traits but do not meet the criteria for a clinical diagnosis of autism. In doing so, we used a dual-stream attentional blink task - a task with heavy processing demands and stimuli displayed simultaneously in both VFs - to elicit inter-hemispheric competition and assess visual field asymmetries. Method The participants were 82 university students, who had never been clinically diagnosed with autism, divided into two groups based on the level of autistic traits that they displayed on the Autism Quotient scale (AQ; Baron-Cohen et al., 2001). Two simultaneous streams of digit-distractors were displayed, one in each VF, and the participants' task was to identify two letter-targets that were displayed unpredictably in the left or right stream. Results We found reduced VF asymmetries in higher autism-trait individuals, with the magnitude of the asymmetry correlating with AQ score. Conclusions We suggest that the reduced VF asymmetries in individuals with higher autism traits may be due to increased perceptual processing capacity (Remington et al., 2009), which reduces hemispheric competition and, thus, visual field asymmetries. The findings also highlight that even subtle differences in the degree of autistic traits in the general population may be associated with differences in visual attention. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102503 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

Fit club: Outcomes from 35-minute daily exercise program for autistic adolescents / Claudia L. HILTON in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102504 Titre : Fit club: Outcomes from 35-minute daily exercise program for autistic adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Claudia L. HILTON, Auteur ; Diane M. COLLINS, Auteur ; Julie JONES, Auteur ; Joanne FLANAGAN, Auteur ; Cora CARILLO, Auteur ; Karen RATCLIFF, Auteur Article en page(s) : p.102504 Langues : Anglais (eng) Mots-clés : Physical fitness  Executive function  Social responsiveness  Body mass index  Cognitive flexibility  School Index. décimale : PER Périodiques Résumé : Background Autistic children and adolescents have academic performance challenges and are often reluctant to participate in physical activities. Executive function (EF) abilities generally remain stable or worsen as autistic children get older and obesity and lack of physical fitness are frequent concerns experienced by these individuals. Finding ways to address these concerns has the potential to improve outcomes in autistic youth. Method We conducted a 12-month, repeated-measures study to examine the effectiveness of a mandatory 35-minute daily school physical activity intervention involving low to moderate exertion for autistic adolescents (n = 29). Changes in fitness, EF, social responsiveness, and restrictive and repetitive behaviors were examined. Results Significant improvements were seen in fitness, EF areas (specifically cognitive flexibility and planning/organizing), restrictive and repetitive behaviors and social responsiveness. Conclusion Findings suggest that participation in a mandatory daily 35-minute physical activity program with low to moderate exertion is feasible and may contribute to improved EF, fitness, restricted and repetitive behavior, and social responsiveness in autistic adolescents. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102504 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] Fit club: Outcomes from 35-minute daily exercise program for autistic adolescents [Texte imprimé et/ou numérique] / Claudia L. HILTON, Auteur ; Diane M. COLLINS, Auteur ; Julie JONES, Auteur ; Joanne FLANAGAN, Auteur ; Cora CARILLO, Auteur ; Karen RATCLIFF, Auteur . - p.102504. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102504 Mots-clés : Physical fitness  Executive function  Social responsiveness  Body mass index  Cognitive flexibility  School Index. décimale : PER Périodiques Résumé : Background Autistic children and adolescents have academic performance challenges and are often reluctant to participate in physical activities. Executive function (EF) abilities generally remain stable or worsen as autistic children get older and obesity and lack of physical fitness are frequent concerns experienced by these individuals. Finding ways to address these concerns has the potential to improve outcomes in autistic youth. Method We conducted a 12-month, repeated-measures study to examine the effectiveness of a mandatory 35-minute daily school physical activity intervention involving low to moderate exertion for autistic adolescents (n = 29). Changes in fitness, EF, social responsiveness, and restrictive and repetitive behaviors were examined. Results Significant improvements were seen in fitness, EF areas (specifically cognitive flexibility and planning/organizing), restrictive and repetitive behaviors and social responsiveness. Conclusion Findings suggest that participation in a mandatory daily 35-minute physical activity program with low to moderate exertion is feasible and may contribute to improved EF, fitness, restricted and repetitive behavior, and social responsiveness in autistic adolescents. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102504 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

Examining parental stress factors in Hong Kong Chinese parents of autistic and neurodevelopmentally atypical children / Xin QI in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102512 Titre : Examining parental stress factors in Hong Kong Chinese parents of autistic and neurodevelopmentally atypical children Type de document : Texte imprimé et/ou numérique Auteurs : Xin QI, Auteur ; Carol K. S. TO, Auteur Article en page(s) : p.102512 Langues : Anglais (eng) Mots-clés : Autism  Broad autism phenotype  Chinese  Coping  Neurodevelopmental disorders  Parental stress  Psychological flexibility  Social support Index. décimale : PER Périodiques Résumé : Background Parenting an autistic child can be physically and mentally challenging. The approach parents take in response to these challenges can vary and may be related to the level of stress they experience. Aims This study compared the stress levels among Hong Kong Chinese parents of autistic children, typically developing (TD) children, and those with other neurodevelopmental disorders (NDDs), and their relationship with associated parental and child?s factors. Methods In this cross-sectional online survey, 314 Chinese parents completed self-reported questionnaires assessing parental stress, child's autism and other NDDs diagnosis, broad autism phenotype (BAP), coping strategies, social support, and parental psychological flexibility (PPF). Hierarchical multiple regression was used to analyze the contribution of these factors to parental stress, and mediation analyses examined how social support and PPF might mediate the relationship between: (1) an autism diagnosis and parental stress, and (2) BAP and parental stress. Results Parents of autistic children reported significantly higher stress levels than other parents. The presence of a child?s autism and other NDDs, along with greater BAP traits, significantly contributed to higher parental stress. Social support and PPF were strong protective factors that mediated the relationship between having an autistic child, exhibiting BAP traits, and parental stress. Conclusions Management for parents of autistic children should focus on promoting social support networks and fostering psychological flexibility to alleviate caregiving burden, especially for those exhibiting greater BAP traits. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102512 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] Examining parental stress factors in Hong Kong Chinese parents of autistic and neurodevelopmentally atypical children [Texte imprimé et/ou numérique] / Xin QI, Auteur ; Carol K. S. TO, Auteur . - p.102512. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102512 Mots-clés : Autism  Broad autism phenotype  Chinese  Coping  Neurodevelopmental disorders  Parental stress  Psychological flexibility  Social support Index. décimale : PER Périodiques Résumé : Background Parenting an autistic child can be physically and mentally challenging. The approach parents take in response to these challenges can vary and may be related to the level of stress they experience. Aims This study compared the stress levels among Hong Kong Chinese parents of autistic children, typically developing (TD) children, and those with other neurodevelopmental disorders (NDDs), and their relationship with associated parental and child?s factors. Methods In this cross-sectional online survey, 314 Chinese parents completed self-reported questionnaires assessing parental stress, child's autism and other NDDs diagnosis, broad autism phenotype (BAP), coping strategies, social support, and parental psychological flexibility (PPF). Hierarchical multiple regression was used to analyze the contribution of these factors to parental stress, and mediation analyses examined how social support and PPF might mediate the relationship between: (1) an autism diagnosis and parental stress, and (2) BAP and parental stress. Results Parents of autistic children reported significantly higher stress levels than other parents. The presence of a child?s autism and other NDDs, along with greater BAP traits, significantly contributed to higher parental stress. Social support and PPF were strong protective factors that mediated the relationship between having an autistic child, exhibiting BAP traits, and parental stress. Conclusions Management for parents of autistic children should focus on promoting social support networks and fostering psychological flexibility to alleviate caregiving burden, especially for those exhibiting greater BAP traits. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102512 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

Comparative analysis of vocal communication and atypicality in mandarin-speaking children with autism spectrum disorder, developmental delay, and typical development / Min LIU in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102513 Titre : Comparative analysis of vocal communication and atypicality in mandarin-speaking children with autism spectrum disorder, developmental delay, and typical development Type de document : Texte imprimé et/ou numérique Auteurs : Min LIU, Auteur ; Yanxia WANG, Auteur ; Xinyu HU, Auteur ; Mudi SUN, Auteur ; Lu QU, Auteur ; Xuling HAN, Auteur ; Hang ZHAO, Auteur ; Haidan LU, Auteur ; Qiaoyun LIU, Auteur Article en page(s) : p.102513 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Communication  Vocalization  Vocal atypicality  Area under the curve  Developmental disorder Index. décimale : PER Périodiques Résumé : Purpose The current study aimed to examine the similarities and differences in vocal characteristics between Mandarin-speaking 36-72-month-old children with autism spectrum disorder (ASD), children with developmental delay (DD), and typically developing (TD) children. Methods We analyzed vocal characteristics during parent-child free play. Video and audio samples were collected from 21 children with ASD, 18 children with DD matched groupwise for developmental level, and 15 TD children matched groupwise for chronological age. Results Compared to children in the DD and TD groups, children with ASD exhibited a significantly higher proportion of nonspeech vocalizations (NSV, p<0.01), atypical vocalizations (ATY, p<0.001), noncommunicative vocalizations (NCV, p<0.001), and no response to others (NR, p<0.001). These four metrics were significantly correlated with children?s performance on the developmental evaluation and intelligence test. Receiver operating characteristic analyses indicated that the area under the curve (AUC) ranged from 0.871-0.978, with moderate accuracy, when using these four metrics to differentiate between children with ASD and TD children; this value improved to 1.000 with high accuracy when combining the four metrics. The AUC ranged from 0.747-0.820 when using the four metrics to differentiate children with ASD from those with DD and improved to 0.857 when combining the four metrics. Conclusion These preliminary data suggest that vocal communication and vocal atypicality may be unique features of children with minimally verbal ASD and that the four metrics-NSV, ATY, NCV, and NR-have the potential to be ASD behavioral markers in screening and diagnosis. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102513 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] Comparative analysis of vocal communication and atypicality in mandarin-speaking children with autism spectrum disorder, developmental delay, and typical development [Texte imprimé et/ou numérique] / Min LIU, Auteur ; Yanxia WANG, Auteur ; Xinyu HU, Auteur ; Mudi SUN, Auteur ; Lu QU, Auteur ; Xuling HAN, Auteur ; Hang ZHAO, Auteur ; Haidan LU, Auteur ; Qiaoyun LIU, Auteur . - p.102513. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102513 Mots-clés : Autism spectrum disorder  Communication  Vocalization  Vocal atypicality  Area under the curve  Developmental disorder Index. décimale : PER Périodiques Résumé : Purpose The current study aimed to examine the similarities and differences in vocal characteristics between Mandarin-speaking 36-72-month-old children with autism spectrum disorder (ASD), children with developmental delay (DD), and typically developing (TD) children. Methods We analyzed vocal characteristics during parent-child free play. Video and audio samples were collected from 21 children with ASD, 18 children with DD matched groupwise for developmental level, and 15 TD children matched groupwise for chronological age. Results Compared to children in the DD and TD groups, children with ASD exhibited a significantly higher proportion of nonspeech vocalizations (NSV, p<0.01), atypical vocalizations (ATY, p<0.001), noncommunicative vocalizations (NCV, p<0.001), and no response to others (NR, p<0.001). These four metrics were significantly correlated with children?s performance on the developmental evaluation and intelligence test. Receiver operating characteristic analyses indicated that the area under the curve (AUC) ranged from 0.871-0.978, with moderate accuracy, when using these four metrics to differentiate between children with ASD and TD children; this value improved to 1.000 with high accuracy when combining the four metrics. The AUC ranged from 0.747-0.820 when using the four metrics to differentiate children with ASD from those with DD and improved to 0.857 when combining the four metrics. Conclusion These preliminary data suggest that vocal communication and vocal atypicality may be unique features of children with minimally verbal ASD and that the four metrics-NSV, ATY, NCV, and NR-have the potential to be ASD behavioral markers in screening and diagnosis. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102513 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

An evaluation of the collateral child and parent outcomes of telehealth-delivered behavioral sleep intervention for Autistic children / Monique CLARKE in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102514 Titre : An evaluation of the collateral child and parent outcomes of telehealth-delivered behavioral sleep intervention for Autistic children Type de document : Texte imprimé et/ou numérique Auteurs : Monique CLARKE, Auteur ; Laurie MCLAY, Auteur ; Karyn FRANCE, Auteur ; Neville BLAMPIED, Auteur Article en page(s) : p.102514 Langues : Anglais (eng) Mots-clés : Sleep  Collateral outcomes  Secondary outcomes  Telehealth  Autism  Neurodivergence Index. décimale : PER Périodiques Résumé : Purpose This research follows two studies that examined the efficacy and acceptability of a stepped-care model of behavioral sleep intervention (BSI) delivered to parents of Autistic children via telehealth (Clarke et al., 2024a, 2024b). The current study investigated the collateral benefits of these interventions on Autistic children?s internalizing and externalizing behaviors, health-related quality of life, and parent ratings of relationship quality, depression, anxiety, stress, and personal sleep quality. Methods and Results Data were available for 17 Autistic children (aged 3-17 years) and 22 parent participants (16 mothers, six fathers) who had received a telehealth-delivered behavioral sleep intervention (TDBSI). Parents completed a range of psychometric assessments at baseline and within six weeks of completing the program. Alongside reduced sleep problem severity (SPS), significant improvements, as indexed by non-negligible Cohen?s d values whose 95?% confidence intervals did not cross zero, were observed in children?s emotional and behavioral difficulties and health-related quality of life. Parents also reported that improvement in their child?s sleep positively influenced their own sleep quality and emotional well-being. There were no significant changes in parental relationship quality post-intervention, probably a ceiling effect. Conclusion TDBSIs have the potential to generate collateral benefits for Autistic children and their families. This finding is consistent with the limited existent research, suggesting that improved sleep may enhance child and parent well-being. Future research should focus on understanding the mechanisms underlying collateral change, including variations in effects among children and parents, and the durability across different telehealth modalities (i.e., self-directed versus therapist-guided) and follow-up intervals. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102514 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] An evaluation of the collateral child and parent outcomes of telehealth-delivered behavioral sleep intervention for Autistic children [Texte imprimé et/ou numérique] / Monique CLARKE, Auteur ; Laurie MCLAY, Auteur ; Karyn FRANCE, Auteur ; Neville BLAMPIED, Auteur . - p.102514. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102514 Mots-clés : Sleep  Collateral outcomes  Secondary outcomes  Telehealth  Autism  Neurodivergence Index. décimale : PER Périodiques Résumé : Purpose This research follows two studies that examined the efficacy and acceptability of a stepped-care model of behavioral sleep intervention (BSI) delivered to parents of Autistic children via telehealth (Clarke et al., 2024a, 2024b). The current study investigated the collateral benefits of these interventions on Autistic children?s internalizing and externalizing behaviors, health-related quality of life, and parent ratings of relationship quality, depression, anxiety, stress, and personal sleep quality. Methods and Results Data were available for 17 Autistic children (aged 3-17 years) and 22 parent participants (16 mothers, six fathers) who had received a telehealth-delivered behavioral sleep intervention (TDBSI). Parents completed a range of psychometric assessments at baseline and within six weeks of completing the program. Alongside reduced sleep problem severity (SPS), significant improvements, as indexed by non-negligible Cohen?s d values whose 95?% confidence intervals did not cross zero, were observed in children?s emotional and behavioral difficulties and health-related quality of life. Parents also reported that improvement in their child?s sleep positively influenced their own sleep quality and emotional well-being. There were no significant changes in parental relationship quality post-intervention, probably a ceiling effect. Conclusion TDBSIs have the potential to generate collateral benefits for Autistic children and their families. This finding is consistent with the limited existent research, suggesting that improved sleep may enhance child and parent well-being. Future research should focus on understanding the mechanisms underlying collateral change, including variations in effects among children and parents, and the durability across different telehealth modalities (i.e., self-directed versus therapist-guided) and follow-up intervals. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102514 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

What are the experiences and support needs of families of autistic children with Extreme (or 'Pathological') Demand Avoidance (E/PDA) behaviours? / Saher NAWAZ in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102515 Titre : What are the experiences and support needs of families of autistic children with Extreme (or 'Pathological') Demand Avoidance (E/PDA) behaviours? Type de document : Texte imprimé et/ou numérique Auteurs : Saher NAWAZ, Auteur ; Susan SPEER, Auteur Article en page(s) : p.102515 Langues : Anglais (eng) Mots-clés : PDA  Autism  Demand avoidance  Diagnosis  Experiences  Qualitative research Index. décimale : PER Périodiques Résumé : Background An increasing number of families are seeking assessment and support for autistic children who present with Extreme (or Pathological) Demand Avoidance (E/PDA) behaviours. However, research suggests the needs of these families may not be well understood or met by services. This study identifies their experiences and support needs, focussing on their interactions with services. Method Qualitative, semi-structured, online interviews with 21 parents of child(ren) with a formal diagnosis of autism and E/PDA behaviours. Interviews were analysed using an inductive, reflexive thematic analysis at a semantic level. Results Four themes describe the distinct experiences of families: (1) Understanding and acceptance of E/PDA behaviours is lacking; (2) Attributing blame: Judgements of E/PDA behaviours by others; (3) Lack of tailored support for E/PDA behaviours; (4) The E/PDA journey results in distress for all family members. Themes form the basis for a new interpretative model of familial experiences of E/PDA in which lack of understanding and acceptance of E/PDA drives neuro-normative judgements about E/PDA behaviours and parenting quality, leading to inadequately tailored support and familial distress. Conclusion Parents' accounts point to a breakdown in service provision for families of children with E/PDA behaviours whose 'complex' or 'atypical' presentation of autism does not fit neatly within existing classification systems and a 'label-based' service model. Improving education and understanding about familial experiences of E/PDA behaviours amongst professionals and services, with greater 'personalisation' and 'formulation-based' approaches is urgently needed to optimise outcomes and prevent harm. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102515 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] What are the experiences and support needs of families of autistic children with Extreme (or 'Pathological') Demand Avoidance (E/PDA) behaviours? [Texte imprimé et/ou numérique] / Saher NAWAZ, Auteur ; Susan SPEER, Auteur . - p.102515. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102515 Mots-clés : PDA  Autism  Demand avoidance  Diagnosis  Experiences  Qualitative research Index. décimale : PER Périodiques Résumé : Background An increasing number of families are seeking assessment and support for autistic children who present with Extreme (or Pathological) Demand Avoidance (E/PDA) behaviours. However, research suggests the needs of these families may not be well understood or met by services. This study identifies their experiences and support needs, focussing on their interactions with services. Method Qualitative, semi-structured, online interviews with 21 parents of child(ren) with a formal diagnosis of autism and E/PDA behaviours. Interviews were analysed using an inductive, reflexive thematic analysis at a semantic level. Results Four themes describe the distinct experiences of families: (1) Understanding and acceptance of E/PDA behaviours is lacking; (2) Attributing blame: Judgements of E/PDA behaviours by others; (3) Lack of tailored support for E/PDA behaviours; (4) The E/PDA journey results in distress for all family members. Themes form the basis for a new interpretative model of familial experiences of E/PDA in which lack of understanding and acceptance of E/PDA drives neuro-normative judgements about E/PDA behaviours and parenting quality, leading to inadequately tailored support and familial distress. Conclusion Parents' accounts point to a breakdown in service provision for families of children with E/PDA behaviours whose 'complex' or 'atypical' presentation of autism does not fit neatly within existing classification systems and a 'label-based' service model. Improving education and understanding about familial experiences of E/PDA behaviours amongst professionals and services, with greater 'personalisation' and 'formulation-based' approaches is urgently needed to optimise outcomes and prevent harm. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102515 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

The effect of exercise training on sleep quality in autism spectrum condition: Systematic review and meta-analysis of randomized controlled trials / Daniel GONZÁLEZ-DEVESA in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102516 Titre : The effect of exercise training on sleep quality in autism spectrum condition: Systematic review and meta-analysis of randomized controlled trials Type de document : Texte imprimé et/ou numérique Auteurs : Daniel GONZÁLEZ-DEVESA, Auteur ; Miguel Adriano SANCHEZ-LASTRA, Auteur ; Benito OUTEDA-MONTEAGUDO, Auteur ; Carlos AYÁN-PÉREZ, Auteur ; José Carlos DIZ-GÓMEZ, Auteur Article en page(s) : p.102516 Langues : Anglais (eng) Mots-clés : Autistic  Exercise  Physical Activity  Sleep duration  Sleep quality Index. décimale : PER Périodiques Résumé : We aimed to analyse the available scientific evidence on the effects of exercise programs on sleep quality in autism spectrum condition. Studies were searched in five electronic databases (MEDLINE/PubMed, Web of Science, EBSCOhost Environment Complete, Dialnet Plus and Scopus) until February 2024 (updated in August 2024). A total of ten randomized clinical trials were included. The pooled mean difference for subjective sleep duration (Child?s Sleep Habits Questionnaire [CSHQ] sub-scale), total CSHQ score, objective sleep duration and objective efficiency were ? 1.62 points (95?% confidence interval [CI] ? 2.34 to ? 0.91; p < 0.001), ?9.43 points (95?% CI: ?16.89 to ?1.97, p < 0.001), 0.42?h (95?% CI: 0.05-0.80, p = 0.03) and 9.91?% (95?% CI: 5.04-14.78, p < 0.001), respectively. In conclusion, exercise can serve as an adjunct therapy for managing sleep-related problems among children on the autism spectrum. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102516 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] The effect of exercise training on sleep quality in autism spectrum condition: Systematic review and meta-analysis of randomized controlled trials [Texte imprimé et/ou numérique] / Daniel GONZÁLEZ-DEVESA, Auteur ; Miguel Adriano SANCHEZ-LASTRA, Auteur ; Benito OUTEDA-MONTEAGUDO, Auteur ; Carlos AYÁN-PÉREZ, Auteur ; José Carlos DIZ-GÓMEZ, Auteur . - p.102516. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102516 Mots-clés : Autistic  Exercise  Physical Activity  Sleep duration  Sleep quality Index. décimale : PER Périodiques Résumé : We aimed to analyse the available scientific evidence on the effects of exercise programs on sleep quality in autism spectrum condition. Studies were searched in five electronic databases (MEDLINE/PubMed, Web of Science, EBSCOhost Environment Complete, Dialnet Plus and Scopus) until February 2024 (updated in August 2024). A total of ten randomized clinical trials were included. The pooled mean difference for subjective sleep duration (Child?s Sleep Habits Questionnaire [CSHQ] sub-scale), total CSHQ score, objective sleep duration and objective efficiency were ? 1.62 points (95?% confidence interval [CI] ? 2.34 to ? 0.91; p < 0.001), ?9.43 points (95?% CI: ?16.89 to ?1.97, p < 0.001), 0.42?h (95?% CI: 0.05-0.80, p = 0.03) and 9.91?% (95?% CI: 5.04-14.78, p < 0.001), respectively. In conclusion, exercise can serve as an adjunct therapy for managing sleep-related problems among children on the autism spectrum. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102516 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

Commentary on: Towards a neurodiversity-affirmative conceptualisation of psycho-education in the context of autism / Daniel SHEPHERD in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102517 Titre : Commentary on: Towards a neurodiversity-affirmative conceptualisation of psycho-education in the context of autism Type de document : Texte imprimé et/ou numérique Auteurs : Daniel SHEPHERD, Auteur Article en page(s) : p.102517 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102517 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] Commentary on: Towards a neurodiversity-affirmative conceptualisation of psycho-education in the context of autism [Texte imprimé et/ou numérique] / Daniel SHEPHERD, Auteur . - p.102517. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102517 Index. décimale : PER Périodiques En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102517 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

Child sleep onset latency mediates parental depression and noncompliance in autistic children / Melanie A. STEARNS in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102518 Titre : Child sleep onset latency mediates parental depression and noncompliance in autistic children Type de document : Texte imprimé et/ou numérique Auteurs : Melanie A. STEARNS, Auteur ; Braden HAYSE, Auteur ; Neetu NAIR, Auteur ; Micah MAZUREK, Auteur ; Ashley F. CURTIS, Auteur ; David BEVERSDORF, Auteur ; Kristin SOHL, Auteur ; Julie MUCKERMAN, Auteur ; Christina S. MCCRAE, Auteur Article en page(s) : p.102518 Langues : Anglais (eng) Mots-clés : Autism  Insomnia  Child  Parent  Depression  Noncompliance Index. décimale : PER Périodiques Résumé : Background Parents diagnosed with depression often report that their children have difficulty following rules and falling asleep. Parents with depression are less likely to be consistent or enforce bedtimes, resulting in the child having fewer bedtime rules and getting less sleep. Over time this may mean the child develops poor sleep habits and difficulty falling asleep. Although these relationships have yet to be studied in children diagnosed with Autism Spectrum Disorder (ASD), it is an important area given that approximately 80?% of autistic children have sleep difficulties. Methods The current study examined whether parent-reported child sleep onset latency (SOL) mediated the relationship between parental depression and child noncompliance. The sample (N=34) consisted of parents (82?% female) reporting on their children aged 6-12 (M=8.63, SD = 2.00; 76.5?% male). All children were diagnosed with ASD and had parent-reported sleep complaints. Measures included the Child Sleep Health Questionnaire (CSHQ), the Pediatric Symptom Checklist (PSC), and a question asking if the parent had been diagnosed with depression (yes/no). Results Greater parent-reported child SOL significantly mediated the relation between increased parental depression and greater noncompliance. Conclusions These results suggest that difficulty falling asleep may help to explain why children of parents who have depression are noncompliant. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102518 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] Child sleep onset latency mediates parental depression and noncompliance in autistic children [Texte imprimé et/ou numérique] / Melanie A. STEARNS, Auteur ; Braden HAYSE, Auteur ; Neetu NAIR, Auteur ; Micah MAZUREK, Auteur ; Ashley F. CURTIS, Auteur ; David BEVERSDORF, Auteur ; Kristin SOHL, Auteur ; Julie MUCKERMAN, Auteur ; Christina S. MCCRAE, Auteur . - p.102518. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102518 Mots-clés : Autism  Insomnia  Child  Parent  Depression  Noncompliance Index. décimale : PER Périodiques Résumé : Background Parents diagnosed with depression often report that their children have difficulty following rules and falling asleep. Parents with depression are less likely to be consistent or enforce bedtimes, resulting in the child having fewer bedtime rules and getting less sleep. Over time this may mean the child develops poor sleep habits and difficulty falling asleep. Although these relationships have yet to be studied in children diagnosed with Autism Spectrum Disorder (ASD), it is an important area given that approximately 80?% of autistic children have sleep difficulties. Methods The current study examined whether parent-reported child sleep onset latency (SOL) mediated the relationship between parental depression and child noncompliance. The sample (N=34) consisted of parents (82?% female) reporting on their children aged 6-12 (M=8.63, SD = 2.00; 76.5?% male). All children were diagnosed with ASD and had parent-reported sleep complaints. Measures included the Child Sleep Health Questionnaire (CSHQ), the Pediatric Symptom Checklist (PSC), and a question asking if the parent had been diagnosed with depression (yes/no). Results Greater parent-reported child SOL significantly mediated the relation between increased parental depression and greater noncompliance. Conclusions These results suggest that difficulty falling asleep may help to explain why children of parents who have depression are noncompliant. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102518 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

Investigating the general psychopathology factor in autistic youth / Hannah Muriel Robb BURROWS in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102519 Titre : Investigating the general psychopathology factor in autistic youth Type de document : Texte imprimé et/ou numérique Auteurs : Hannah Muriel Robb BURROWS, Auteur ; Brianne DERBY, Auteur ; Laura DE LA ROCHE, Auteur ; Melissa SUSKO, Auteur ; Rob NICOLSON, Auteur ; Stelios GEORGIADES, Auteur ; Jessica JONES, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Elizabeth KELLEY, Auteur Article en page(s) : p.102519 Langues : Anglais (eng) Mots-clés : General psychopathology  factor  Autism  Internalizing  Externalizing Index. décimale : PER Périodiques Résumé : Background Autistic youth are at higher risk of presenting with co-occurring internalizing (I) (i.e., anxiety and depression) and externalizing (E) (i.e., aggression and impulsivity) disorders (Bauminger et al., 2010). The Child Behavior Checklist for ages 6-18 (CBCL/6-18; Achenbach & Rescorla, 2001) is a measure of I-E disorders and symptoms in autistic and neurotypical youth, providing norm-referenced subscales as factors for each form of psychopathology. The general psychopathology or "p" factor may provide a better measure of co-occurring disorders in autism as it has not been evaluated in this population contextually to date. The p factor proposes that psychopathological disorders come from the same etiological factor, implying that we can measure all I-E disorders as indicators of p. Method Using archival data from the Province of Ontario Neurodevelopmental Disorders (POND) Network, (N = 782) autistic youths' raw scores from the CBCL/6-18 were analyzed using two confirmatory factor analyses (CFAs): an I-E CFA and a p factor CFA. An exploratory factor analysis (EFA) was also conducted to determine the best-fitting factor structure. Results A chi-square difference test compared each CFA to find the best model fit. Results reported each model as individually significant, however, based on recommendations from Hoyle and Panter (1995), neither model had an acceptable fit. Conclusions Given that neither the p factor nor the internalizing/externalizing factor models had appropriate fit, it is recommended that future research investigate whether the CBCL/6-18 is the most appropriate measure for assessing co-occurring symptoms in autistic youth. The results of the EFA also suggest that the CBCL may not be the most appropriate measure for autistic youth. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102519 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] Investigating the general psychopathology factor in autistic youth [Texte imprimé et/ou numérique] / Hannah Muriel Robb BURROWS, Auteur ; Brianne DERBY, Auteur ; Laura DE LA ROCHE, Auteur ; Melissa SUSKO, Auteur ; Rob NICOLSON, Auteur ; Stelios GEORGIADES, Auteur ; Jessica JONES, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Elizabeth KELLEY, Auteur . - p.102519. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102519 Mots-clés : General psychopathology  factor  Autism  Internalizing  Externalizing Index. décimale : PER Périodiques Résumé : Background Autistic youth are at higher risk of presenting with co-occurring internalizing (I) (i.e., anxiety and depression) and externalizing (E) (i.e., aggression and impulsivity) disorders (Bauminger et al., 2010). The Child Behavior Checklist for ages 6-18 (CBCL/6-18; Achenbach & Rescorla, 2001) is a measure of I-E disorders and symptoms in autistic and neurotypical youth, providing norm-referenced subscales as factors for each form of psychopathology. The general psychopathology or "p" factor may provide a better measure of co-occurring disorders in autism as it has not been evaluated in this population contextually to date. The p factor proposes that psychopathological disorders come from the same etiological factor, implying that we can measure all I-E disorders as indicators of p. Method Using archival data from the Province of Ontario Neurodevelopmental Disorders (POND) Network, (N = 782) autistic youths' raw scores from the CBCL/6-18 were analyzed using two confirmatory factor analyses (CFAs): an I-E CFA and a p factor CFA. An exploratory factor analysis (EFA) was also conducted to determine the best-fitting factor structure. Results A chi-square difference test compared each CFA to find the best model fit. Results reported each model as individually significant, however, based on recommendations from Hoyle and Panter (1995), neither model had an acceptable fit. Conclusions Given that neither the p factor nor the internalizing/externalizing factor models had appropriate fit, it is recommended that future research investigate whether the CBCL/6-18 is the most appropriate measure for assessing co-occurring symptoms in autistic youth. The results of the EFA also suggest that the CBCL may not be the most appropriate measure for autistic youth. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102519 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

Correlates of age at first alcohol use among a US-based sample of autistic underage youth / Calliope HOLINGUE in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102520 Titre : Correlates of age at first alcohol use among a US-based sample of autistic underage youth Type de document : Texte imprimé et/ou numérique Auteurs : Calliope HOLINGUE, Auteur ; Laura Graham HOLMES, Auteur ; Julia CUSANO, Auteur ; Emily F. ROTHMAN, Auteur Article en page(s) : p.102520 Langues : Anglais (eng) Mots-clés : Autism  Alcohol  Substance use  Youth Index. décimale : PER Périodiques Résumé : Background Recent research has identified risk factors for hazardous alcohol use among autistic individuals, but correlates of age at first alcohol use are unclear. Methods This study analyzed 49?U.S.-based autistic youth (ages 16-20) who had ever consumed alcohol. Participants were categorized as being less than 16 years old (n=28) or 16 years or older (n=21) at first alcohol use. The analysis aimed to descriptively compare youth with younger versus older age at first alcohol use. Results Younger age at first alcohol use was associated with hazardous alcohol use, higher levels of anxiety, and lower masking of autistic traits Conclusions These findings demonstrate that autistic youth are at risk for underage alcohol use. More research is needed on alcohol and substance use in this population to develop tailored prevention and intervention programs. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102520 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] Correlates of age at first alcohol use among a US-based sample of autistic underage youth [Texte imprimé et/ou numérique] / Calliope HOLINGUE, Auteur ; Laura Graham HOLMES, Auteur ; Julia CUSANO, Auteur ; Emily F. ROTHMAN, Auteur . - p.102520. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102520 Mots-clés : Autism  Alcohol  Substance use  Youth Index. décimale : PER Périodiques Résumé : Background Recent research has identified risk factors for hazardous alcohol use among autistic individuals, but correlates of age at first alcohol use are unclear. Methods This study analyzed 49?U.S.-based autistic youth (ages 16-20) who had ever consumed alcohol. Participants were categorized as being less than 16 years old (n=28) or 16 years or older (n=21) at first alcohol use. The analysis aimed to descriptively compare youth with younger versus older age at first alcohol use. Results Younger age at first alcohol use was associated with hazardous alcohol use, higher levels of anxiety, and lower masking of autistic traits Conclusions These findings demonstrate that autistic youth are at risk for underage alcohol use. More research is needed on alcohol and substance use in this population to develop tailored prevention and intervention programs. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102520 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

Virtual reality educational scenarios for students with ASD: Instruments validation and design of STEM programmatic contents / Rui Manuel SILVA in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102521 Titre : Virtual reality educational scenarios for students with ASD: Instruments validation and design of STEM programmatic contents Type de document : Texte imprimé et/ou numérique Auteurs : Rui Manuel SILVA, Auteur ; Paulo MARTINS, Auteur ; Tânia ROCHA, Auteur Article en page(s) : p.102521 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Virtual learning environments  Inclusive education  Virtual reality  STEM education Index. décimale : PER Périodiques Résumé : Background Virtual Reality (VR) is making education more engaging and accessible, especially for students with Autism Spectrum Disorders (ASD), promoting inclusion and the development of STEM skills in innovative ways. The literature still reveals a significant gap in terms of appropriate educational resources adapted to the specific needs of these students, resulting in difficulties in their inclusion. With the growing need for inclusive approaches in education, it is essential to find solutions to support these students. The aim of this study is to validate the data collection methodology that will enable the development of Virtual Learning Environments with STEM content for students with ASD. Methods The Design Science Research (DSR) methodology was used to develop a VR artefact for students with ASD. In addition, the Delphi method was applied in the expert involvement phase, which will contribute to the validation of the artefact's specific requirements. Both will allow for an inclusive and distinctive approach to the development of an artefact, with the aim of offering an innovative educational experience, meeting the varied needs and learning styles of students with ASD, optimising the effectiveness of the proposed VLE. Results The results show a strong acceptance among experts, highlighting the potential positive impact of this approach, although there are aspects to be improved to ensure a more comprehensive and effective approach. Conclusions This study highlights the successful validation of an innovative virtual reality programme for students with ASD, highlighting the importance of interdisciplinary collaboration and the strong contribution to the advancement of inclusive education. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102521 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] Virtual reality educational scenarios for students with ASD: Instruments validation and design of STEM programmatic contents [Texte imprimé et/ou numérique] / Rui Manuel SILVA, Auteur ; Paulo MARTINS, Auteur ; Tânia ROCHA, Auteur . - p.102521. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102521 Mots-clés : Autism spectrum disorder  Virtual learning environments  Inclusive education  Virtual reality  STEM education Index. décimale : PER Périodiques Résumé : Background Virtual Reality (VR) is making education more engaging and accessible, especially for students with Autism Spectrum Disorders (ASD), promoting inclusion and the development of STEM skills in innovative ways. The literature still reveals a significant gap in terms of appropriate educational resources adapted to the specific needs of these students, resulting in difficulties in their inclusion. With the growing need for inclusive approaches in education, it is essential to find solutions to support these students. The aim of this study is to validate the data collection methodology that will enable the development of Virtual Learning Environments with STEM content for students with ASD. Methods The Design Science Research (DSR) methodology was used to develop a VR artefact for students with ASD. In addition, the Delphi method was applied in the expert involvement phase, which will contribute to the validation of the artefact's specific requirements. Both will allow for an inclusive and distinctive approach to the development of an artefact, with the aim of offering an innovative educational experience, meeting the varied needs and learning styles of students with ASD, optimising the effectiveness of the proposed VLE. Results The results show a strong acceptance among experts, highlighting the potential positive impact of this approach, although there are aspects to be improved to ensure a more comprehensive and effective approach. Conclusions This study highlights the successful validation of an innovative virtual reality programme for students with ASD, highlighting the importance of interdisciplinary collaboration and the strong contribution to the advancement of inclusive education. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102521 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

Family experiences with supplemental social security income and legal guardianship for autistic adults: A mixed-methods study / Emily F. FERGUSON in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102522 Titre : Family experiences with supplemental social security income and legal guardianship for autistic adults: A mixed-methods study Type de document : Texte imprimé et/ou numérique Auteurs : Emily F. FERGUSON, Auteur ; Elaine B. CLARKE, Auteur ; Noa SCHISTERMAN, Auteur ; Catherine LORD, Auteur Article en page(s) : p.102522 Langues : Anglais (eng) Mots-clés : Social services  Transition to adulthood  Legal issues  Community participation  Supplemental Social Security Income  Guardianship  Autism Spectrum Disorder Index. décimale : PER Périodiques Résumé : Background Family interactions with the Supplemental Social Security Income (SSI) program and the decision to pursue legal guardianship are poorly understood in services research for autistic adults. Methods We conducted a mixed-methods study and incorporated quantitative survey data from 122 autistic adults in an existing longitudinal cohort with qualitative interviews with 12 autistic adults and/or legal guardians. We explored sociodemographic, developmental, and behavioral features associated with the likelihood of having SSI and a legal guardian at 25 years old. Spoken interviews were transcribed verbatim, and interviews were analyzed using a rapid qualitative analytic approach. Results There were quantitative differences in whether families were able to obtain SSI and guardianship based on intelligence quotient (IQ) scores, adaptive behavior, and autistic characteristics, but not by race, ethnicity, or maternal education. Qualitative data analysis revealed six themes that highlighted the challenges associated with obtaining and maintaining SSI, along with the complex, nuanced decisions associated with legal guardianship. Families noted many challenges in navigating these procedures and some potential benefits for each unique circumstance. Conclusions These findings offer new perspectives on experiences associated with pursuing SSI benefits and legal guardianship for autistic adults, including similarities and key differences in these procedures. Findings also provide suggestions for future research to improve coordination and supports for families throughout adulthood. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102522 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] Family experiences with supplemental social security income and legal guardianship for autistic adults: A mixed-methods study [Texte imprimé et/ou numérique] / Emily F. FERGUSON, Auteur ; Elaine B. CLARKE, Auteur ; Noa SCHISTERMAN, Auteur ; Catherine LORD, Auteur . - p.102522. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102522 Mots-clés : Social services  Transition to adulthood  Legal issues  Community participation  Supplemental Social Security Income  Guardianship  Autism Spectrum Disorder Index. décimale : PER Périodiques Résumé : Background Family interactions with the Supplemental Social Security Income (SSI) program and the decision to pursue legal guardianship are poorly understood in services research for autistic adults. Methods We conducted a mixed-methods study and incorporated quantitative survey data from 122 autistic adults in an existing longitudinal cohort with qualitative interviews with 12 autistic adults and/or legal guardians. We explored sociodemographic, developmental, and behavioral features associated with the likelihood of having SSI and a legal guardian at 25 years old. Spoken interviews were transcribed verbatim, and interviews were analyzed using a rapid qualitative analytic approach. Results There were quantitative differences in whether families were able to obtain SSI and guardianship based on intelligence quotient (IQ) scores, adaptive behavior, and autistic characteristics, but not by race, ethnicity, or maternal education. Qualitative data analysis revealed six themes that highlighted the challenges associated with obtaining and maintaining SSI, along with the complex, nuanced decisions associated with legal guardianship. Families noted many challenges in navigating these procedures and some potential benefits for each unique circumstance. Conclusions These findings offer new perspectives on experiences associated with pursuing SSI benefits and legal guardianship for autistic adults, including similarities and key differences in these procedures. Findings also provide suggestions for future research to improve coordination and supports for families throughout adulthood. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102522 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

Skill-based treatment for challenging behavior in autism spectrum disorder: A scoping review of treatment characteristics and outcomes / Kristin M. HUSTYI in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102523 Titre : Skill-based treatment for challenging behavior in autism spectrum disorder: A scoping review of treatment characteristics and outcomes Type de document : Texte imprimé et/ou numérique Auteurs : Kristin M. HUSTYI, Auteur ; Jesse J. LOGUE, Auteur ; Scott S. HALL, Auteur Article en page(s) : p.102523 Langues : Anglais (eng) Mots-clés : Skill-based treatment  Practical functional assessment  Challenging behavior  Functional communication training  Interview-informed synthesized contingency analysis  Scoping review Index. décimale : PER Périodiques Résumé : Background Behavioral interventions based on the principles of applied behavior analysis (ABA) are considered the gold standard approach for treating challenging behaviors commonly exhibited by children with autism spectrum disorder (ASD). However, questions have arisen concerning the safety of implementing traditional ABA procedures for the treatment of challenging behavior in natural settings. Over the past decade, a treatment package known as skill-based treatment (SBT) has emerged that may allow challenging behaviors in this population to be addressed in a safe, efficient, and effective manner. Methods We reviewed and summarized studies utilizing SBT published in English between 2014 and September 2023 using PsychINFO and PubMed databases. Two independent reviewers screened citations for inclusion. Data abstraction was performed by one reviewer and verified by a second reviewer. Results Twenty-one studies (3 consecutive controlled case series and 18 utilizing single-case experimental designs) met the inclusion criteria describing SBT conducted with 87 individuals. The majority of individuals treated with SBT were autistic children with language levels varying from non-vocal to fully fluent. Treatments were implemented in a variety of settings at least 1-2 times per week, with treatment requiring a range of 4 - 48.5?h of clinician time. Rates of challenging behavior were reported to decrease by 98.2?% (range: 90-100?%) on average. Treatments were implemented via telehealth for 8 individuals (9.2%). Data concerning treatment maintenance was reported for just 7 individuals (8.1?%). Conclusions SBT is a potentially effective treatment procedure for challenging behavior that can be conducted in a variety of settings including the child?s home, school, and via telehealth. However, future research is needed to understand the long-term effectiveness of SBT. Randomized controlled trials of SBT are also necessary in order to study the safety and efficacy of this treatment approach. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102523 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] Skill-based treatment for challenging behavior in autism spectrum disorder: A scoping review of treatment characteristics and outcomes [Texte imprimé et/ou numérique] / Kristin M. HUSTYI, Auteur ; Jesse J. LOGUE, Auteur ; Scott S. HALL, Auteur . - p.102523. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102523 Mots-clés : Skill-based treatment  Practical functional assessment  Challenging behavior  Functional communication training  Interview-informed synthesized contingency analysis  Scoping review Index. décimale : PER Périodiques Résumé : Background Behavioral interventions based on the principles of applied behavior analysis (ABA) are considered the gold standard approach for treating challenging behaviors commonly exhibited by children with autism spectrum disorder (ASD). However, questions have arisen concerning the safety of implementing traditional ABA procedures for the treatment of challenging behavior in natural settings. Over the past decade, a treatment package known as skill-based treatment (SBT) has emerged that may allow challenging behaviors in this population to be addressed in a safe, efficient, and effective manner. Methods We reviewed and summarized studies utilizing SBT published in English between 2014 and September 2023 using PsychINFO and PubMed databases. Two independent reviewers screened citations for inclusion. Data abstraction was performed by one reviewer and verified by a second reviewer. Results Twenty-one studies (3 consecutive controlled case series and 18 utilizing single-case experimental designs) met the inclusion criteria describing SBT conducted with 87 individuals. The majority of individuals treated with SBT were autistic children with language levels varying from non-vocal to fully fluent. Treatments were implemented in a variety of settings at least 1-2 times per week, with treatment requiring a range of 4 - 48.5?h of clinician time. Rates of challenging behavior were reported to decrease by 98.2?% (range: 90-100?%) on average. Treatments were implemented via telehealth for 8 individuals (9.2%). Data concerning treatment maintenance was reported for just 7 individuals (8.1?%). Conclusions SBT is a potentially effective treatment procedure for challenging behavior that can be conducted in a variety of settings including the child?s home, school, and via telehealth. However, future research is needed to understand the long-term effectiveness of SBT. Randomized controlled trials of SBT are also necessary in order to study the safety and efficacy of this treatment approach. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102523 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

Brief report: Social relationships among autistic young adults with varying cognitive abilities / Dena GOHARI in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102524 Titre : Brief report: Social relationships among autistic young adults with varying cognitive abilities Type de document : Texte imprimé et/ou numérique Auteurs : Dena GOHARI, Auteur ; Jamie PARK, Auteur ; Hillary SCHILTZ, Auteur ; Catherine LORD, Auteur Article en page(s) : p.102524 Langues : Anglais (eng) Mots-clés : Social relationships  Young adulthood  Autism  Cognitive ability  Informant report Index. décimale : PER Périodiques Résumé : Background Autism is characterized by social difficulties, yet many autistic people value and desire social relationships. Given the limited research on autism in adulthood, particularly among those with lower cognitive ability, this study aimed 1) to compare self- vs informant-report of social relationships (acquaintances, friendships, and interpersonal difficulties) and 2) to compare social relationships, between more cognitively able (MCA) and less cognitively able (LCA) autistic young adults. Method Participants included 101 autistic young adults (Mage=25.90; SD=1.41; 82.0?% male; 79.8?% White) and their informants. Participants were interviewed, and the Interpersonal Difficulties and Social Relationships sections of the Social and Emotional Functioning Interview (SEF) were analyzed. Participants were classified as MCA (IQ?70) or LCA (IQ<70). Results For the MCA sample, informant and self-report SEF scores were all positively correlated and did not have significantly different median values. Weaker and non-significant associations emerged for social contexts outside of the home (e.g., at work) and more abstract concepts (e.g., quality of relationships). Although cognitive ability impacted the extreme SEF scores (e.g., having self-initiated reciprocal friendships), many social difficulties were shared by LCA and MCA young adults, according to informant reports. Conclusions This study is one of few on social relationships and autism to focus on adulthood and include LCA young adults. Results indicate that informant-report provides useful information on more concrete aspects of social relationships in this population. Many autistic young adults, and LCA young adults in particular, may benefit from additional social supports, yet it is also essential to collaboratively consider what types of social experiences and relationships are desired and feasible for each person. More research and intervention tailored to LCA autistic young adults are needed. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102524 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] Brief report: Social relationships among autistic young adults with varying cognitive abilities [Texte imprimé et/ou numérique] / Dena GOHARI, Auteur ; Jamie PARK, Auteur ; Hillary SCHILTZ, Auteur ; Catherine LORD, Auteur . - p.102524. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102524 Mots-clés : Social relationships  Young adulthood  Autism  Cognitive ability  Informant report Index. décimale : PER Périodiques Résumé : Background Autism is characterized by social difficulties, yet many autistic people value and desire social relationships. Given the limited research on autism in adulthood, particularly among those with lower cognitive ability, this study aimed 1) to compare self- vs informant-report of social relationships (acquaintances, friendships, and interpersonal difficulties) and 2) to compare social relationships, between more cognitively able (MCA) and less cognitively able (LCA) autistic young adults. Method Participants included 101 autistic young adults (Mage=25.90; SD=1.41; 82.0?% male; 79.8?% White) and their informants. Participants were interviewed, and the Interpersonal Difficulties and Social Relationships sections of the Social and Emotional Functioning Interview (SEF) were analyzed. Participants were classified as MCA (IQ?70) or LCA (IQ<70). Results For the MCA sample, informant and self-report SEF scores were all positively correlated and did not have significantly different median values. Weaker and non-significant associations emerged for social contexts outside of the home (e.g., at work) and more abstract concepts (e.g., quality of relationships). Although cognitive ability impacted the extreme SEF scores (e.g., having self-initiated reciprocal friendships), many social difficulties were shared by LCA and MCA young adults, according to informant reports. Conclusions This study is one of few on social relationships and autism to focus on adulthood and include LCA young adults. Results indicate that informant-report provides useful information on more concrete aspects of social relationships in this population. Many autistic young adults, and LCA young adults in particular, may benefit from additional social supports, yet it is also essential to collaboratively consider what types of social experiences and relationships are desired and feasible for each person. More research and intervention tailored to LCA autistic young adults are needed. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102524 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

Which emerging autism features at 12 months of age are associated with later parent-child interaction? / Chengcheng KE in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102525 Titre : Which emerging autism features at 12 months of age are associated with later parent-child interaction? Type de document : Texte imprimé et/ou numérique Auteurs : Chengcheng KE, Auteur ; Lesley-Anne CARTER, Auteur ; Jonathan GREEN, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; Kristelle HUDRY, Auteur ; Josephine BARBARO, Auteur ; Cheryl DISSANAYAKE, Auteur ; Murray MAYBERY, Auteur ; Slonims VICKY, Auteur ; Leonie SEGAL, Auteur ; Kandice VARCIN, Auteur ; Ming Wai WAN, Auteur Article en page(s) : p.102525 Langues : Anglais (eng) Mots-clés : Parental sensitivity  Parent-infant interaction  Maternal sensitivity  Elevated likelihood of autism  Autism signs  Sensorimotor Index. décimale : PER Périodiques Résumé : Background Parent-child interactions (PCI) in infants with an elevated likelihood (EL) of autism start to diverge from other infants toward the end of the first year. This divergence is often attributed to emerging features of autism impacting infant social interactions in ways that become increasingly amplified. The aim was to identify which, if any, 12-month autism features were associated with later PCI qualities. Method Twelve-month-old infants (N = 103) with early autism features (3+ on the Social Attention and Communication Surveillance-Revised tool) were assessed on the Autism Observation Scale for Infants (AOSI) at 12 and 18 months, and on free play PCI using the Manchester Assessment of Caregiver-Infant Interaction at 18 months. Results AOSI autism features at 12-months were associated with 18-month PCI qualities, independent of 18-month autism features. Specifically, infants with emerging features in social attention areas later showed less attentiveness to parents and lower dyadic mutuality. By contrast, infants with emerging sensorimotor atypicality/delay later showed increased attentiveness to parents and lower negative affect, their parents were more sensitively responsive, and their interactions were more mutual. Emotional regulation scores had no significant association with later PCI. Conclusions The findings support the notion that PCI changes in EL infants are rooted in the transactional impact of early emerging autism-related features, which may have differential effects on PCI. Pending replication in a larger sample using a detailed measure of early autism features, the findings suggest that early autism features may amplify or elicit interactions. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102525 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] Which emerging autism features at 12 months of age are associated with later parent-child interaction? [Texte imprimé et/ou numérique] / Chengcheng KE, Auteur ; Lesley-Anne CARTER, Auteur ; Jonathan GREEN, Auteur ; Andrew J. O. WHITEHOUSE, Auteur ; Kristelle HUDRY, Auteur ; Josephine BARBARO, Auteur ; Cheryl DISSANAYAKE, Auteur ; Murray MAYBERY, Auteur ; Slonims VICKY, Auteur ; Leonie SEGAL, Auteur ; Kandice VARCIN, Auteur ; Ming Wai WAN, Auteur . - p.102525. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102525 Mots-clés : Parental sensitivity  Parent-infant interaction  Maternal sensitivity  Elevated likelihood of autism  Autism signs  Sensorimotor Index. décimale : PER Périodiques Résumé : Background Parent-child interactions (PCI) in infants with an elevated likelihood (EL) of autism start to diverge from other infants toward the end of the first year. This divergence is often attributed to emerging features of autism impacting infant social interactions in ways that become increasingly amplified. The aim was to identify which, if any, 12-month autism features were associated with later PCI qualities. Method Twelve-month-old infants (N = 103) with early autism features (3+ on the Social Attention and Communication Surveillance-Revised tool) were assessed on the Autism Observation Scale for Infants (AOSI) at 12 and 18 months, and on free play PCI using the Manchester Assessment of Caregiver-Infant Interaction at 18 months. Results AOSI autism features at 12-months were associated with 18-month PCI qualities, independent of 18-month autism features. Specifically, infants with emerging features in social attention areas later showed less attentiveness to parents and lower dyadic mutuality. By contrast, infants with emerging sensorimotor atypicality/delay later showed increased attentiveness to parents and lower negative affect, their parents were more sensitively responsive, and their interactions were more mutual. Emotional regulation scores had no significant association with later PCI. Conclusions The findings support the notion that PCI changes in EL infants are rooted in the transactional impact of early emerging autism-related features, which may have differential effects on PCI. Pending replication in a larger sample using a detailed measure of early autism features, the findings suggest that early autism features may amplify or elicit interactions. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102525 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545

The BTBR T+ Itpr3tf/J mouse strain as a model to study the genetic, immune, and metabolic origins of neurodevelopmental disorders / M. P. VISCOMI in Research in Autism Spectrum Disorders, 119 (January 2025)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 119 (January 2025) . - p.102526 Titre : The BTBR T+ Itpr3tf/J mouse strain as a model to study the genetic, immune, and metabolic origins of neurodevelopmental disorders Type de document : Texte imprimé et/ou numérique Auteurs : M. P. VISCOMI, Auteur ; J. CZYRSKA, Auteur ; D. WINIARCZYK, Auteur ; M. M. ZI?TEK, Auteur ; S. SAMPINO, Auteur Article en page(s) : p.102526 Langues : Anglais (eng) Mots-clés : Autism  Mouse model  BTBR strain  Metabolism Index. décimale : PER Périodiques Résumé : The BTBR T+ Itpr3tf/J (BTBR) mouse strain manifests a peculiar behavioral phenotype that mirrors the core symptomatology of autism spectrum disorders, including alterations in social-communicative behavioral domains, and the presence of repetitive/stereotyped behaviors. Concurrent immune and metabolic imbalances characterize the BTBR phenotype and are exacerbated by specific gene mutations, resulting in severe multi-organs imbalances that recapitulate the symptoms of human autoimmune and metabolic disorders. The present review aims to retrace and summarize state-of-the-art regarding the genetic, immune, and metabolic features of the BTBR strain and address its potential use as a valid model to study the multi-system etiology and pathogenesis of neurodevelopmental disorders. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102526 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545 [article] The BTBR T+ Itpr3tf/J mouse strain as a model to study the genetic, immune, and metabolic origins of neurodevelopmental disorders [Texte imprimé et/ou numérique] / M. P. VISCOMI, Auteur ; J. CZYRSKA, Auteur ; D. WINIARCZYK, Auteur ; M. M. ZI?TEK, Auteur ; S. SAMPINO, Auteur . - p.102526. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 119 (January 2025) . - p.102526 Mots-clés : Autism  Mouse model  BTBR strain  Metabolism Index. décimale : PER Périodiques Résumé : The BTBR T+ Itpr3tf/J (BTBR) mouse strain manifests a peculiar behavioral phenotype that mirrors the core symptomatology of autism spectrum disorders, including alterations in social-communicative behavioral domains, and the presence of repetitive/stereotyped behaviors. Concurrent immune and metabolic imbalances characterize the BTBR phenotype and are exacerbated by specific gene mutations, resulting in severe multi-organs imbalances that recapitulate the symptoms of human autoimmune and metabolic disorders. The present review aims to retrace and summarize state-of-the-art regarding the genetic, immune, and metabolic features of the BTBR strain and address its potential use as a valid model to study the multi-system etiology and pathogenesis of neurodevelopmental disorders. En ligne : https://dx.doi.org/10.1016/j.rasd.2024.102526 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=545