Dépouillements

Editorial: The acetaminophen scare: association vs causation / Eric FOMBONNE in Journal of Child Psychology and Psychiatry, 66-11 (November 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1621-1626 Titre : Editorial: The acetaminophen scare: association vs causation Type de document : texte imprimé Auteurs : Eric FOMBONNE, Auteur Article en page(s) : p.1621-1626 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : With high twin concordance and sibling recurrence risk, the influence of genetic factors in the etiology of autism is not disputed. The contribution of environmental risk to the etiology of autism is less well established. While the prevalence increase observed worldwide has fueled beliefs of an epidemic driven by environmental changes, the evidence for such interpretations of the secular change in prevalence is lacking (Fombonne, 2025). In epidemiological surveys, no clustering in time or space has been reported that could point to candidate exposures. Thus, observational (cohort and case?control) studies have been wide-ranging and exploratory rather than hypothesis-driven. In light of growing evidence of atypical development occurring in the first months of life (Dawson et al., 2023, Lancet Neurology, 22, 244), environmental risk research in autism has focused on prenatal or periconceptional exposures. In the last 20?years, a myriad of associations have been reported between autism risk and prenatal exposure to: pesticides, phthalates, air pollutants, maternal fever or infection during pregnancy, inter-pregnancy interval, lack of folic acid supplementation, vitamin D deficiency, maternal diet, advancing parental age, exposure to heavy metals, prenatal exposure to antidepressants, valproic acid, benzodiazepines, acetaminophen, maternal smoking, cannabis or alcohol use during pregnancy, maternal obesity and excessive gestational weight gain, prematurity, low birth weight, maternal immune activation, C-section, use of oxytocin, assisted reproductive technologies, and countless others. With few exceptions (advanced parental age, prenatal exposure to valproic acid), associations have not been replicated, or when they have, their causal nature has not been established. En ligne : https://doi.org/10.1111/jcpp.70064 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=570 [article] Editorial: The acetaminophen scare: association vs causation [texte imprimé] / Eric FOMBONNE, Auteur . - p.1621-1626. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1621-1626 Index. décimale : PER Périodiques Résumé : With high twin concordance and sibling recurrence risk, the influence of genetic factors in the etiology of autism is not disputed. The contribution of environmental risk to the etiology of autism is less well established. While the prevalence increase observed worldwide has fueled beliefs of an epidemic driven by environmental changes, the evidence for such interpretations of the secular change in prevalence is lacking (Fombonne, 2025). In epidemiological surveys, no clustering in time or space has been reported that could point to candidate exposures. Thus, observational (cohort and case?control) studies have been wide-ranging and exploratory rather than hypothesis-driven. In light of growing evidence of atypical development occurring in the first months of life (Dawson et al., 2023, Lancet Neurology, 22, 244), environmental risk research in autism has focused on prenatal or periconceptional exposures. In the last 20?years, a myriad of associations have been reported between autism risk and prenatal exposure to: pesticides, phthalates, air pollutants, maternal fever or infection during pregnancy, inter-pregnancy interval, lack of folic acid supplementation, vitamin D deficiency, maternal diet, advancing parental age, exposure to heavy metals, prenatal exposure to antidepressants, valproic acid, benzodiazepines, acetaminophen, maternal smoking, cannabis or alcohol use during pregnancy, maternal obesity and excessive gestational weight gain, prematurity, low birth weight, maternal immune activation, C-section, use of oxytocin, assisted reproductive technologies, and countless others. With few exceptions (advanced parental age, prenatal exposure to valproic acid), associations have not been replicated, or when they have, their causal nature has not been established. En ligne : https://doi.org/10.1111/jcpp.70064 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=570

Maternal caregiving moderates relations between maternal childhood maltreatment and infant cortisol regulation / Miriam CHASSON in Journal of Child Psychology and Psychiatry, 66-11 (November 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1627-1641 Titre : Maternal caregiving moderates relations between maternal childhood maltreatment and infant cortisol regulation Type de document : texte imprimé Auteurs : Miriam CHASSON, Auteur ; Jennifer KHOURY, Auteur ; Michelle BOSQUET ENLOW, Auteur ; Karlen LYONS-RUTH, Auteur Article en page(s) : p.1627-1641 Langues : Anglais (eng) Mots-clés : Infancy  cortisol  intergenerational transmission  abuse  neglect  mother–infant interaction Index. décimale : PER Périodiques Résumé : Background Children of maltreated mothers are at increased risk for adverse physical and psychological health. Both prenatal and postnatal alterations in offspring biological stress systems have been proposed as mechanisms contributing to such transmission. The aim of the current study was to assess whether maternal postnatal care of the infant moderated any effect of maternal childhood maltreatment on infant cortisol output during a mild stressor at 4?months of age. Methods Participants included 181 mother?infant dyads, screened at recruitment to result in 57.4% reporting one or more forms of childhood maltreatment. Mothers were assessed for quality of caregiving, and infants were assessed for infant salivary cortisol output during the Still-Face Paradigm at infant age 4?months. Maternal childhood maltreatment was assessed using the Maltreatment and Abuse Chronology of Exposure (MACE) self-report scales. Results Greater severity of maternal childhood neglect interacted with higher levels of maternal disoriented caregiving to predict higher infant cortisol output over the course of the Still-Face Paradigm. In contrast, maternal childhood abuse interacted with higher levels of maternal negative-intrusion to predict lower infant cortisol output. Greater maternal role confusion was linked to greater infant cortisol output regardless of maternal maltreatment history. Conclusions Maternal caregiving may moderate the effects of risk factors existing prior to the infant's birth. Disoriented caregiving in the context of maternal childhood neglect and negative-intrusive behavior in the context of maternal childhood abuse were associated with opposite directions of effect on infant stress hormone output. The results suggest that interventions addressing risks from both prenatal and postnatal periods may be most effective in mitigating intergenerational effects of maltreatment. En ligne : https://doi.org/10.1111/jcpp.14171 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=570 [article] Maternal caregiving moderates relations between maternal childhood maltreatment and infant cortisol regulation [texte imprimé] / Miriam CHASSON, Auteur ; Jennifer KHOURY, Auteur ; Michelle BOSQUET ENLOW, Auteur ; Karlen LYONS-RUTH, Auteur . - p.1627-1641. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1627-1641 Mots-clés : Infancy  cortisol  intergenerational transmission  abuse  neglect  mother–infant interaction Index. décimale : PER Périodiques Résumé : Background Children of maltreated mothers are at increased risk for adverse physical and psychological health. Both prenatal and postnatal alterations in offspring biological stress systems have been proposed as mechanisms contributing to such transmission. The aim of the current study was to assess whether maternal postnatal care of the infant moderated any effect of maternal childhood maltreatment on infant cortisol output during a mild stressor at 4?months of age. Methods Participants included 181 mother?infant dyads, screened at recruitment to result in 57.4% reporting one or more forms of childhood maltreatment. Mothers were assessed for quality of caregiving, and infants were assessed for infant salivary cortisol output during the Still-Face Paradigm at infant age 4?months. Maternal childhood maltreatment was assessed using the Maltreatment and Abuse Chronology of Exposure (MACE) self-report scales. Results Greater severity of maternal childhood neglect interacted with higher levels of maternal disoriented caregiving to predict higher infant cortisol output over the course of the Still-Face Paradigm. In contrast, maternal childhood abuse interacted with higher levels of maternal negative-intrusion to predict lower infant cortisol output. Greater maternal role confusion was linked to greater infant cortisol output regardless of maternal maltreatment history. Conclusions Maternal caregiving may moderate the effects of risk factors existing prior to the infant's birth. Disoriented caregiving in the context of maternal childhood neglect and negative-intrusive behavior in the context of maternal childhood abuse were associated with opposite directions of effect on infant stress hormone output. The results suggest that interventions addressing risks from both prenatal and postnatal periods may be most effective in mitigating intergenerational effects of maltreatment. En ligne : https://doi.org/10.1111/jcpp.14171 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=570

The roles of parental verbal communication and child characteristics in the transmission and maintenance of social fears / Selin ZEYTINOGLU in Journal of Child Psychology and Psychiatry, 66-11 (November 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1642-1652 Titre : The roles of parental verbal communication and child characteristics in the transmission and maintenance of social fears Type de document : texte imprimé Auteurs : Selin ZEYTINOGLU, Auteur ; Lauren K. WHITE, Auteur ; Santiago MORALES, Auteur ; Kathryn DEGNAN, Auteur ; Heather A. HENDERSON, Auteur ; Koraly PEREZ-EDGAR, Auteur ; Daniel S. PINE, Auteur ; Nathan A. FOX, Auteur Article en page(s) : p.1642-1652 Langues : Anglais (eng) Mots-clés : behavioral inhibition  anxiety  mother–child interaction  social learning  interpretation bias Index. décimale : PER Périodiques Résumé : Background Although social anxiety runs in families, little is known about how parents and children contribute to the intergenerational transmission of social fears. We examined whether mothers transfer social fear beliefs to their children through verbal communication and how children's behavioral inhibition and social anxiety contribute to this transmission. The associations of children's social fear beliefs with peer avoidance and interpretation bias were also examined. Methods Participants (N?=?291, 54% female) were followed from toddlerhood to middle childhood. Behavioral inhibition was assessed at ages 2 and 3. At the 10-year assessment, mother?child dyads participated in a conversation task. Mothers received ambiguous information about hypothetical peers and then talked to their children about vignettes involving these peers. Mothers' positive and negative statements were coded. Prior to the conversation, dyads reported their own social fear beliefs. Post-conversation, children rated their social fear beliefs and completed symbolic peer avoidance and social interpretive bias tasks. Children self-reported their social anxiety. Results Mothers' positive statements mediated the paths from maternal social fear beliefs and behavioral inhibition to children's post-conversation social fear beliefs. Mothers' negative statements also mediated the link between mothers' fear beliefs and children's post-conversation fear beliefs, but only among children with heightened anxiety. Children's post-conversation social fear beliefs were, in turn, associated with children's peer avoidance and interpretation bias. Conclusions Findings suggest that maternal verbal communication serves as a mechanism in the relation between parent and child social fear beliefs, and children's fear beliefs, in turn, predict their symbolic peer avoidance and interpretative biases. Children with heightened anxiety were particularly impacted by their mothers' negative statements, whereas behavioral inhibition predicted fewer maternal positive statements. Targeting mothers' social fear beliefs and verbal communication patterns may help prevent the intergenerational transmission of social fear. En ligne : https://doi.org/10.1111/jcpp.14169 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=570 [article] The roles of parental verbal communication and child characteristics in the transmission and maintenance of social fears [texte imprimé] / Selin ZEYTINOGLU, Auteur ; Lauren K. WHITE, Auteur ; Santiago MORALES, Auteur ; Kathryn DEGNAN, Auteur ; Heather A. HENDERSON, Auteur ; Koraly PEREZ-EDGAR, Auteur ; Daniel S. PINE, Auteur ; Nathan A. FOX, Auteur . - p.1642-1652. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1642-1652 Mots-clés : behavioral inhibition  anxiety  mother–child interaction  social learning  interpretation bias Index. décimale : PER Périodiques Résumé : Background Although social anxiety runs in families, little is known about how parents and children contribute to the intergenerational transmission of social fears. We examined whether mothers transfer social fear beliefs to their children through verbal communication and how children's behavioral inhibition and social anxiety contribute to this transmission. The associations of children's social fear beliefs with peer avoidance and interpretation bias were also examined. Methods Participants (N?=?291, 54% female) were followed from toddlerhood to middle childhood. Behavioral inhibition was assessed at ages 2 and 3. At the 10-year assessment, mother?child dyads participated in a conversation task. Mothers received ambiguous information about hypothetical peers and then talked to their children about vignettes involving these peers. Mothers' positive and negative statements were coded. Prior to the conversation, dyads reported their own social fear beliefs. Post-conversation, children rated their social fear beliefs and completed symbolic peer avoidance and social interpretive bias tasks. Children self-reported their social anxiety. Results Mothers' positive statements mediated the paths from maternal social fear beliefs and behavioral inhibition to children's post-conversation social fear beliefs. Mothers' negative statements also mediated the link between mothers' fear beliefs and children's post-conversation fear beliefs, but only among children with heightened anxiety. Children's post-conversation social fear beliefs were, in turn, associated with children's peer avoidance and interpretation bias. Conclusions Findings suggest that maternal verbal communication serves as a mechanism in the relation between parent and child social fear beliefs, and children's fear beliefs, in turn, predict their symbolic peer avoidance and interpretative biases. Children with heightened anxiety were particularly impacted by their mothers' negative statements, whereas behavioral inhibition predicted fewer maternal positive statements. Targeting mothers' social fear beliefs and verbal communication patterns may help prevent the intergenerational transmission of social fear. En ligne : https://doi.org/10.1111/jcpp.14169 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=570

Childhood trauma, adolescent risk behaviours and cardiovascular health indices in the 2004 Pelotas Birth Cohort / Megan BAILEY in Journal of Child Psychology and Psychiatry, 66-11 (November 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1653-1663 Titre : Childhood trauma, adolescent risk behaviours and cardiovascular health indices in the 2004 Pelotas Birth Cohort Type de document : texte imprimé Auteurs : Megan BAILEY, Auteur ; Graeme FAIRCHILD, Auteur ; Gemma HAMMERTON, Auteur ; Iná S. SANTOS, Auteur ; Luciana TOVO-RODRIGUES, Auteur ; Joseph MURRAY, Auteur ; Alicia MATIJASEVICH, Auteur ; Sarah L. HALLIGAN, Auteur Article en page(s) : p.1653-1663 Langues : Anglais (eng) Mots-clés : Childhood trauma  adolescent  substance use  psychophysiology  risk behaviours Index. décimale : PER Périodiques Résumé : Background Childhood trauma has been associated with increased risk of substance use and poor sleep, with these factors linked to subsequent poor cardiovascular health. However, there has been little longitudinal research exploring these associations in adolescence, especially in low- and middle-income countries (LMICs). To address this, we investigated longitudinal pathways from trauma to risk behaviours and cardiovascular health indices among adolescents in the 2004 Pelotas Birth Cohort, Brazil. Methods Lifetime cumulative trauma was assessed via caregiver reports up to age 11, and combined adolescent/caregiver reports at ages 15 and 18. At age 18, current problematic alcohol use, smoking, illicit drug use and sleep duration were measured via self-report and resting heart rate (HR) and blood pressure (BP) were assessed. We tested for trauma risk behaviour?HR/BP associations using multivariable regression, population attributable fractions and counterfactual mediation. Results Of 4,229 adolescents (51.9% boys), 81.9% were trauma-exposed by age 18. Cumulative trauma up to ages 15 and 18 increased the odds of age 18 alcohol, smoking and drug use (adjusted ORs: 1.25?1.44). Sleep duration was unrelated to childhood trauma. Population attributable fractions indicated that childhood trauma explained ≥28% of age 18 substance use. Unexpectedly, greater trauma exposure was associated with lower resting HR and BP. Substance use partially mediated the effect of trauma on cardiovascular health indices. Conclusions Trauma is associated with substance use in LMIC adolescents. Prevention and intervention strategies targeting trauma are critical given this significant burden. Our finding that trauma predicts lower HR/BP warrants further exploration given well-established associations between trauma and poorer cardiovascular health in adulthood. En ligne : https://doi.org/10.1111/jcpp.14173 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=570 [article] Childhood trauma, adolescent risk behaviours and cardiovascular health indices in the 2004 Pelotas Birth Cohort [texte imprimé] / Megan BAILEY, Auteur ; Graeme FAIRCHILD, Auteur ; Gemma HAMMERTON, Auteur ; Iná S. SANTOS, Auteur ; Luciana TOVO-RODRIGUES, Auteur ; Joseph MURRAY, Auteur ; Alicia MATIJASEVICH, Auteur ; Sarah L. HALLIGAN, Auteur . - p.1653-1663. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1653-1663 Mots-clés : Childhood trauma  adolescent  substance use  psychophysiology  risk behaviours Index. décimale : PER Périodiques Résumé : Background Childhood trauma has been associated with increased risk of substance use and poor sleep, with these factors linked to subsequent poor cardiovascular health. However, there has been little longitudinal research exploring these associations in adolescence, especially in low- and middle-income countries (LMICs). To address this, we investigated longitudinal pathways from trauma to risk behaviours and cardiovascular health indices among adolescents in the 2004 Pelotas Birth Cohort, Brazil. Methods Lifetime cumulative trauma was assessed via caregiver reports up to age 11, and combined adolescent/caregiver reports at ages 15 and 18. At age 18, current problematic alcohol use, smoking, illicit drug use and sleep duration were measured via self-report and resting heart rate (HR) and blood pressure (BP) were assessed. We tested for trauma risk behaviour?HR/BP associations using multivariable regression, population attributable fractions and counterfactual mediation. Results Of 4,229 adolescents (51.9% boys), 81.9% were trauma-exposed by age 18. Cumulative trauma up to ages 15 and 18 increased the odds of age 18 alcohol, smoking and drug use (adjusted ORs: 1.25?1.44). Sleep duration was unrelated to childhood trauma. Population attributable fractions indicated that childhood trauma explained ≥28% of age 18 substance use. Unexpectedly, greater trauma exposure was associated with lower resting HR and BP. Substance use partially mediated the effect of trauma on cardiovascular health indices. Conclusions Trauma is associated with substance use in LMIC adolescents. Prevention and intervention strategies targeting trauma are critical given this significant burden. Our finding that trauma predicts lower HR/BP warrants further exploration given well-established associations between trauma and poorer cardiovascular health in adulthood. En ligne : https://doi.org/10.1111/jcpp.14173 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=570

Gaze behavior, facial emotion processing, and neural underpinnings: A comparison of adolescents with autism spectrum disorder and conduct disorder / Antonia TKALCEC in Journal of Child Psychology and Psychiatry, 66-11 (November 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1664-1674 Titre : Gaze behavior, facial emotion processing, and neural underpinnings: A comparison of adolescents with autism spectrum disorder and conduct disorder Type de document : texte imprimé Auteurs : Antonia TKALCEC, Auteur ; Alessandro BALDASSARRI, Auteur ; Alex JUNGHANS, Auteur ; Vithusan SOMASUNDARAM, Auteur ; Willeke M. MENKS, Auteur ; Lynn V. FEHLBAUM, Auteur ; Reka BORBAS, Auteur ; Nora RASCHLE, Auteur ; Gudrun SEEGER-SCHNEIDER, Auteur ; Bettina JENNY, Auteur ; Susanne WALITZA, Auteur ; David M. COLE, Auteur ; Philipp STERZER, Auteur ; Francesco SANTINI, Auteur ; Evelyn HERBRECHT, Auteur ; Ana CUBILLO, Auteur ; Christina STADLER, Auteur Article en page(s) : p.1664-1674 Langues : Anglais (eng) Mots-clés : Conduct disorder  autism spectrum disorders  emotion processing  eye gaze  brain activation Index. décimale : PER Périodiques Résumé : Background Facial emotion processing deficits and atypical eye gaze are often described in individuals with autism spectrum disorder (ASD) and those with conduct disorder (CD) and high callous unemotional (CU) traits. Yet, the underlying neural mechanisms of these deficits are still unclear. The aim of this study was to investigate if eye gaze can partially account for the differences in brain activation in youth with ASD, with CD, and typically developing youth (TD). Methods In total, 105 adolescent participants (NCD?=?39, NASD?=?27, NTD?=?39; mean age?=?15.59?years) underwent a brain functional imaging session including eye tracking during an implicit emotion processing task while parents/caregivers completed questionnaires. Group differences in gaze behavior (number of fixations to the eye and mouth regions) for different facial expressions (neutral, fearful, angry) presented in the task were investigated using Bayesian analyses. Full-factorial models were used to investigate group differences in brain activation with and without including gaze behavior parameters and focusing on brain regions underlying facial emotion processing (insula, amygdala, and medial prefrontal cortex). Results Youth with ASD showed increased fixations on the mouth compared to TD and CD groups. CD participants with high CU traits tended to show fewer fixations to the eye region compared to TD for all emotions. Brain imaging results show higher right anterior insula activation in the ASD compared with the CD group when angry faces were presented. The inclusion of gaze behavior parameters in the model reduced the size of that cluster. Conclusions Differences in insula activation may be partially explained by gaze behavior. This implies an important role of gaze behavior in facial emotion processing, which should be considered for future brain imaging studies. In addition, our results suggest that targeting gaze behavior in interventions might be potentially beneficial for disorders showing impairments associated with the processing of emotional faces. The relation between eye gaze, CU traits, and neural function in different diagnoses needs further clarification in larger samples. En ligne : https://doi.org/10.1111/jcpp.14172 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571 [article] Gaze behavior, facial emotion processing, and neural underpinnings: A comparison of adolescents with autism spectrum disorder and conduct disorder [texte imprimé] / Antonia TKALCEC, Auteur ; Alessandro BALDASSARRI, Auteur ; Alex JUNGHANS, Auteur ; Vithusan SOMASUNDARAM, Auteur ; Willeke M. MENKS, Auteur ; Lynn V. FEHLBAUM, Auteur ; Reka BORBAS, Auteur ; Nora RASCHLE, Auteur ; Gudrun SEEGER-SCHNEIDER, Auteur ; Bettina JENNY, Auteur ; Susanne WALITZA, Auteur ; David M. COLE, Auteur ; Philipp STERZER, Auteur ; Francesco SANTINI, Auteur ; Evelyn HERBRECHT, Auteur ; Ana CUBILLO, Auteur ; Christina STADLER, Auteur . - p.1664-1674. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1664-1674 Mots-clés : Conduct disorder  autism spectrum disorders  emotion processing  eye gaze  brain activation Index. décimale : PER Périodiques Résumé : Background Facial emotion processing deficits and atypical eye gaze are often described in individuals with autism spectrum disorder (ASD) and those with conduct disorder (CD) and high callous unemotional (CU) traits. Yet, the underlying neural mechanisms of these deficits are still unclear. The aim of this study was to investigate if eye gaze can partially account for the differences in brain activation in youth with ASD, with CD, and typically developing youth (TD). Methods In total, 105 adolescent participants (NCD?=?39, NASD?=?27, NTD?=?39; mean age?=?15.59?years) underwent a brain functional imaging session including eye tracking during an implicit emotion processing task while parents/caregivers completed questionnaires. Group differences in gaze behavior (number of fixations to the eye and mouth regions) for different facial expressions (neutral, fearful, angry) presented in the task were investigated using Bayesian analyses. Full-factorial models were used to investigate group differences in brain activation with and without including gaze behavior parameters and focusing on brain regions underlying facial emotion processing (insula, amygdala, and medial prefrontal cortex). Results Youth with ASD showed increased fixations on the mouth compared to TD and CD groups. CD participants with high CU traits tended to show fewer fixations to the eye region compared to TD for all emotions. Brain imaging results show higher right anterior insula activation in the ASD compared with the CD group when angry faces were presented. The inclusion of gaze behavior parameters in the model reduced the size of that cluster. Conclusions Differences in insula activation may be partially explained by gaze behavior. This implies an important role of gaze behavior in facial emotion processing, which should be considered for future brain imaging studies. In addition, our results suggest that targeting gaze behavior in interventions might be potentially beneficial for disorders showing impairments associated with the processing of emotional faces. The relation between eye gaze, CU traits, and neural function in different diagnoses needs further clarification in larger samples. En ligne : https://doi.org/10.1111/jcpp.14172 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571

Dynamics of depression symptoms in adolescents during three types of psychotherapy and post-treatment follow-up / Madison AITKEN in Journal of Child Psychology and Psychiatry, 66-11 (November 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1675-1687 Titre : Dynamics of depression symptoms in adolescents during three types of psychotherapy and post-treatment follow-up Type de document : texte imprimé Auteurs : Madison AITKEN, Auteur ; Sharon A. S. NEUFELD, Auteur ; Clement MA, Auteur ; Impact CONSORTIUM, Auteur ; Ian M. GOODYER, Auteur Article en page(s) : p.1675-1687 Langues : Anglais (eng) Mots-clés : Depression  intervention  psychotherapy  adolescence  symptomatology Index. décimale : PER Périodiques Résumé : Background According to the network theory of mental disorders, psychopathology emerges from symptoms that causally influence one another and create interconnections and feedback loops that maintain atypical mental states. Analysis of symptom networks during and following psychotherapy may provide clues to some of the mechanisms through which change occurs. Youth with depression are an important population in which to better understand psychotherapy mechanisms because current evidence-based interventions for this population show only modest effects. Methods Participants were adolescents with major depressive disorder (N?=?465; ages 11?17; 75% female) in a randomized controlled trial comparing cognitive behavioral therapy, short-term psychoanalytical psychotherapy, and brief psychosocial intervention (IMPACT, ISRCTN83033550). Eleven self-reported depression symptoms were used to compute two longitudinal networks: (1) treatment phase, using baseline, 6 and 12?weeks data; and (2) follow-up phase, using 36, 52, and 86?weeks data. Results During the treatment phase, all depression symptoms were interconnected. Symptoms of insomnia and fatigue showed the highest outstrength centrality (ability to predict other symptoms over time). In contrast, few symptoms were interconnected during the post-treatment phase except worthlessness, which had the highest outstrength centrality. Allowing network parameters to differ across the three treatment types improved model fit during the treatment phase and revealed that symptoms with the highest outstrength centrality varied by treatment type. Conclusions Individual symptoms may make key contributions to subsequent depressive psychopathology in adolescents. Longitudinal network analysis reveals that insomnia and fatigue predict other symptoms, allowing for consideration of specific mechanisms associated with depression treatment. The findings further suggest that negative cognitions about the self may emerge as a central putative cognitive vulnerability in those with a history of depression. Our exploratory findings also suggest that the three therapies (cognitive behavioral therapy, short-term psychoanalytical psychotherapy, and brief psychosocial intervention) may have achieved equifinality in part through different mechanisms. En ligne : https://doi.org/10.1111/jcpp.14175 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571 [article] Dynamics of depression symptoms in adolescents during three types of psychotherapy and post-treatment follow-up [texte imprimé] / Madison AITKEN, Auteur ; Sharon A. S. NEUFELD, Auteur ; Clement MA, Auteur ; Impact CONSORTIUM, Auteur ; Ian M. GOODYER, Auteur . - p.1675-1687. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1675-1687 Mots-clés : Depression  intervention  psychotherapy  adolescence  symptomatology Index. décimale : PER Périodiques Résumé : Background According to the network theory of mental disorders, psychopathology emerges from symptoms that causally influence one another and create interconnections and feedback loops that maintain atypical mental states. Analysis of symptom networks during and following psychotherapy may provide clues to some of the mechanisms through which change occurs. Youth with depression are an important population in which to better understand psychotherapy mechanisms because current evidence-based interventions for this population show only modest effects. Methods Participants were adolescents with major depressive disorder (N?=?465; ages 11?17; 75% female) in a randomized controlled trial comparing cognitive behavioral therapy, short-term psychoanalytical psychotherapy, and brief psychosocial intervention (IMPACT, ISRCTN83033550). Eleven self-reported depression symptoms were used to compute two longitudinal networks: (1) treatment phase, using baseline, 6 and 12?weeks data; and (2) follow-up phase, using 36, 52, and 86?weeks data. Results During the treatment phase, all depression symptoms were interconnected. Symptoms of insomnia and fatigue showed the highest outstrength centrality (ability to predict other symptoms over time). In contrast, few symptoms were interconnected during the post-treatment phase except worthlessness, which had the highest outstrength centrality. Allowing network parameters to differ across the three treatment types improved model fit during the treatment phase and revealed that symptoms with the highest outstrength centrality varied by treatment type. Conclusions Individual symptoms may make key contributions to subsequent depressive psychopathology in adolescents. Longitudinal network analysis reveals that insomnia and fatigue predict other symptoms, allowing for consideration of specific mechanisms associated with depression treatment. The findings further suggest that negative cognitions about the self may emerge as a central putative cognitive vulnerability in those with a history of depression. Our exploratory findings also suggest that the three therapies (cognitive behavioral therapy, short-term psychoanalytical psychotherapy, and brief psychosocial intervention) may have achieved equifinality in part through different mechanisms. En ligne : https://doi.org/10.1111/jcpp.14175 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571

Predictors of Environmental Sensitivity in Syrian refugee children / Andrew K. MAY in Journal of Child Psychology and Psychiatry, 66-11 (November 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1688-1702 Titre : Predictors of Environmental Sensitivity in Syrian refugee children Type de document : texte imprimé Auteurs : Andrew K. MAY, Auteur ; Demelza SMEETH, Auteur ; Fiona MCEWEN, Auteur ; Elie KARAM, Auteur ; Michael PLUESS, Auteur Article en page(s) : p.1688-1702 Langues : Anglais (eng) Mots-clés : Environmental Sensitivity  predictors  refugees  children  Syria Index. décimale : PER Périodiques Résumé : Background Although more prone to psychopathology on average, refugee children differ in their response to adversity. Growing evidence attributes some of these individual differences to varying levels of Environmental Sensitivity ? the extent to which children perceive and process contextual influences. However, there is limited knowledge of how Environmental Sensitivity is developmentally influenced, particularly in the refugee setting. Methods Here, we investigated whether individual-, family- and community-level predictors (psychosocial and genetic) were associated with self-reported Environmental Sensitivity and its subscales (measured using the 12-item Highly Sensitive Child Scale). Participants were a subsample (n?=?1,409) from a cohort of Syrian refugee children and their biological mothers, recruited from informal tented settlements in Lebanon. Multivariate adaptive regression spline models were fitted to identify the best selection from over 40 available predictors. Results Twelve predictors of Environmental Sensitivity emerged, with the five most commonly selected being maternal behavioural control, human insecurity, positive home experiences, maternal anxiety and child-reported child abuse, the latter three of which were also suggested to predict changes in sensitivity over a 12-month period. Some predictors such as maternal PTSD, war exposure and bullying showed a non-linear, V-shape relationship with sensitivity. All effect sizes, however, were small. Conclusions Our findings suggest that both highly supportive and highly adverse contextual factors associate with greater childhood Environmental Sensitivity, in line with current theorising. Despite previous suggestive evidence, we did not find that polygenic scores for autism and attention deficit hyperactivity disorder predicted sensitivity. Further research into predictors of Environmental Sensitivity is encouraged, as this may help with improved assessment of the trait in children. En ligne : https://doi.org/10.1111/jcpp.14178 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571 [article] Predictors of Environmental Sensitivity in Syrian refugee children [texte imprimé] / Andrew K. MAY, Auteur ; Demelza SMEETH, Auteur ; Fiona MCEWEN, Auteur ; Elie KARAM, Auteur ; Michael PLUESS, Auteur . - p.1688-1702. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1688-1702 Mots-clés : Environmental Sensitivity  predictors  refugees  children  Syria Index. décimale : PER Périodiques Résumé : Background Although more prone to psychopathology on average, refugee children differ in their response to adversity. Growing evidence attributes some of these individual differences to varying levels of Environmental Sensitivity ? the extent to which children perceive and process contextual influences. However, there is limited knowledge of how Environmental Sensitivity is developmentally influenced, particularly in the refugee setting. Methods Here, we investigated whether individual-, family- and community-level predictors (psychosocial and genetic) were associated with self-reported Environmental Sensitivity and its subscales (measured using the 12-item Highly Sensitive Child Scale). Participants were a subsample (n?=?1,409) from a cohort of Syrian refugee children and their biological mothers, recruited from informal tented settlements in Lebanon. Multivariate adaptive regression spline models were fitted to identify the best selection from over 40 available predictors. Results Twelve predictors of Environmental Sensitivity emerged, with the five most commonly selected being maternal behavioural control, human insecurity, positive home experiences, maternal anxiety and child-reported child abuse, the latter three of which were also suggested to predict changes in sensitivity over a 12-month period. Some predictors such as maternal PTSD, war exposure and bullying showed a non-linear, V-shape relationship with sensitivity. All effect sizes, however, were small. Conclusions Our findings suggest that both highly supportive and highly adverse contextual factors associate with greater childhood Environmental Sensitivity, in line with current theorising. Despite previous suggestive evidence, we did not find that polygenic scores for autism and attention deficit hyperactivity disorder predicted sensitivity. Further research into predictors of Environmental Sensitivity is encouraged, as this may help with improved assessment of the trait in children. En ligne : https://doi.org/10.1111/jcpp.14178 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571

Predictive and incremental validity of adolescent callous-unemotional traits: longitudinal prediction of antisocial and social outcomes in early adulthood / Erin P. VAUGHAN in Journal of Child Psychology and Psychiatry, 66-11 (November 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1703-1712 Titre : Predictive and incremental validity of adolescent callous-unemotional traits: longitudinal prediction of antisocial and social outcomes in early adulthood Type de document : texte imprimé Auteurs : Erin P. VAUGHAN, Auteur ; Paul J. FRICK, Auteur ; James V. RAY, Auteur ; Laura C. THORNTON, Auteur ; Tina D. Wall MYERS, Auteur ; Emily L. ROBERTSON, Auteur ; Toni M. WALKER, Auteur ; Laurence STEINBERG, Auteur ; Elizabeth CAUFFMAN, Auteur Article en page(s) : p.1703-1712 Langues : Anglais (eng) Mots-clés : Callous-unemotional traits  antisocial behavior  social development  early adulthood outcomes Index. décimale : PER Périodiques Résumé : Background Callous-unemotional (CU) traits were recently added as a diagnostic specifier for disruptive behavior disorders, largely due to their prognostic utility. However, past longitudinal research has yielded mixed results when investigating associations between CU traits and long-term outcomes, particularly when controlling for the individual's level of antisocial behavior. Methods The current study investigated the longitudinal predictive utility of CU traits in a sample of 1,216 adolescents involved in the juvenile justice system who were followed for 7?years after their first arrest. Growth models of CU traits throughout adolescence were used to predict a variety of young adult outcomes (e.g., aggression, financially-motivated crime, and social impairment) while controlling for the trajectory of antisocial behavior throughout adolescence. Results Results indicated that adolescent CU traits predicted a variety of antisocial and social outcomes. While several of these associations were no longer significant after accounting for antisocial behavior, CU traits incrementally predicted several early adulthood outcomes (e.g., more arrests, greater aggression, lower quality relationships with friends and romantic partners) when controlling for both the level and degree of change in antisocial behavior. Conclusions Results support that CU traits are clinically useful when identifying risk for problematic outcomes and highlight the need for effective intervention for youth with elevated CU traits. En ligne : https://doi.org/10.1111/jcpp.14181 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571 [article] Predictive and incremental validity of adolescent callous-unemotional traits: longitudinal prediction of antisocial and social outcomes in early adulthood [texte imprimé] / Erin P. VAUGHAN, Auteur ; Paul J. FRICK, Auteur ; James V. RAY, Auteur ; Laura C. THORNTON, Auteur ; Tina D. Wall MYERS, Auteur ; Emily L. ROBERTSON, Auteur ; Toni M. WALKER, Auteur ; Laurence STEINBERG, Auteur ; Elizabeth CAUFFMAN, Auteur . - p.1703-1712. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1703-1712 Mots-clés : Callous-unemotional traits  antisocial behavior  social development  early adulthood outcomes Index. décimale : PER Périodiques Résumé : Background Callous-unemotional (CU) traits were recently added as a diagnostic specifier for disruptive behavior disorders, largely due to their prognostic utility. However, past longitudinal research has yielded mixed results when investigating associations between CU traits and long-term outcomes, particularly when controlling for the individual's level of antisocial behavior. Methods The current study investigated the longitudinal predictive utility of CU traits in a sample of 1,216 adolescents involved in the juvenile justice system who were followed for 7?years after their first arrest. Growth models of CU traits throughout adolescence were used to predict a variety of young adult outcomes (e.g., aggression, financially-motivated crime, and social impairment) while controlling for the trajectory of antisocial behavior throughout adolescence. Results Results indicated that adolescent CU traits predicted a variety of antisocial and social outcomes. While several of these associations were no longer significant after accounting for antisocial behavior, CU traits incrementally predicted several early adulthood outcomes (e.g., more arrests, greater aggression, lower quality relationships with friends and romantic partners) when controlling for both the level and degree of change in antisocial behavior. Conclusions Results support that CU traits are clinically useful when identifying risk for problematic outcomes and highlight the need for effective intervention for youth with elevated CU traits. En ligne : https://doi.org/10.1111/jcpp.14181 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571

Impact of a Pediatric Mental Health Crisis Service in the emergency department on hospital resource utilization: an interrupted time series analysis / Vineet PADMANABHAN in Journal of Child Psychology and Psychiatry, 66-11 (November 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1713-1723 Titre : Impact of a Pediatric Mental Health Crisis Service in the emergency department on hospital resource utilization: an interrupted time series analysis Type de document : texte imprimé Auteurs : Vineet PADMANABHAN, Auteur ; Cayla A. BELLAGARDA, Auteur ; Laura DONDZILO, Auteur ; Sarah MACDONALD, Auteur ; Alexander HEGARTY, Auteur ; Michelle MORRIS, Auteur ; Zamia PEDRO, Auteur Article en page(s) : p.1713-1723 Langues : Anglais (eng) Mots-clés : Crisis care  emergency department  mental health  inpatient care  interrupted time series analysis Index. décimale : PER Périodiques Résumé : Background Lengthening waitlists, reduced outpatient care availability, and increased numbers of children experiencing mental health (MH) crises have strained emergency departments (EDs). EDs facilitate access to immediate intervention and triage to acute services but are often underresourced and undertrained to manage the unique needs of mental health crises. The combination of demand, complexity, and resources required encouraged the development of specialized mental health crisis services. In 2021, CAMHS Crisis Connect (CCC) was established at Perth Children's Hospital and aims to improve patient flow, reduce hospital resource utilization, and improve the experience of children experiencing crises. Methods The aim of the current study is to examine a pediatric crisis intervention service in a West Australian context. We implement interrupted time series analyses (ITS), a quasi-experimental statistical methodology allowing us to make causal interpretations of CCC impact on hospital resource utilization. Results The key effect here is the substantial reduction in presentations and re-presentations to ED and inpatient wards that are sustained across the long term and directly attributable to CCC. However, there is an increasing length of stay in ED and the very small and potentially not clinically meaningful reduction in inpatient bed occupancy, which requires further investigation. Conclusions Our results support specialized, multi-faceted crisis care programs in ED to ensure accessibility of acute, intensive care for those with severe and complex needs, supporting the journey for children who may be more effectively managed in community and outpatient settings. En ligne : https://doi.org/10.1111/jcpp.14182 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571 [article] Impact of a Pediatric Mental Health Crisis Service in the emergency department on hospital resource utilization: an interrupted time series analysis [texte imprimé] / Vineet PADMANABHAN, Auteur ; Cayla A. BELLAGARDA, Auteur ; Laura DONDZILO, Auteur ; Sarah MACDONALD, Auteur ; Alexander HEGARTY, Auteur ; Michelle MORRIS, Auteur ; Zamia PEDRO, Auteur . - p.1713-1723. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1713-1723 Mots-clés : Crisis care  emergency department  mental health  inpatient care  interrupted time series analysis Index. décimale : PER Périodiques Résumé : Background Lengthening waitlists, reduced outpatient care availability, and increased numbers of children experiencing mental health (MH) crises have strained emergency departments (EDs). EDs facilitate access to immediate intervention and triage to acute services but are often underresourced and undertrained to manage the unique needs of mental health crises. The combination of demand, complexity, and resources required encouraged the development of specialized mental health crisis services. In 2021, CAMHS Crisis Connect (CCC) was established at Perth Children's Hospital and aims to improve patient flow, reduce hospital resource utilization, and improve the experience of children experiencing crises. Methods The aim of the current study is to examine a pediatric crisis intervention service in a West Australian context. We implement interrupted time series analyses (ITS), a quasi-experimental statistical methodology allowing us to make causal interpretations of CCC impact on hospital resource utilization. Results The key effect here is the substantial reduction in presentations and re-presentations to ED and inpatient wards that are sustained across the long term and directly attributable to CCC. However, there is an increasing length of stay in ED and the very small and potentially not clinically meaningful reduction in inpatient bed occupancy, which requires further investigation. Conclusions Our results support specialized, multi-faceted crisis care programs in ED to ensure accessibility of acute, intensive care for those with severe and complex needs, supporting the journey for children who may be more effectively managed in community and outpatient settings. En ligne : https://doi.org/10.1111/jcpp.14182 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571

Mother-preschooler RSA synchrony and self-regulation as antecedents of developmental psychopathology in early childhood / Longfeng LI in Journal of Child Psychology and Psychiatry, 66-11 (November 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1724-1735 Titre : Mother-preschooler RSA synchrony and self-regulation as antecedents of developmental psychopathology in early childhood Type de document : texte imprimé Auteurs : Longfeng LI, Auteur ; Sara SUCH, Auteur ; Erika LUNKENHEIMER, Auteur Article en page(s) : p.1724-1735 Langues : Anglais (eng) Mots-clés : Behavior problems  biomarkers  developmental psychopathology  parenting  parent–child interaction Index. décimale : PER Périodiques Résumé : Background We examined whether mother-preschooler respiratory sinus arrhythmia (RSA) synchrony and self-regulation, as potential biological antecedents of developmental psychopathology, interacted to shape children's later behavior problems directly and indirectly via harsh parenting. Methods Mother-preschooler dyads (N?=?135; 53% female) were oversampled for familial risk. Mother-rated harsh parenting and child behavior problems at ages 3 and 4?years were modeled as latent change scores across ages. Age 3 mother?child RSA synchrony was estimated with multilevel modeling as the concurrent effects of maternal RSA on child RSA during a challenging parent?child task. Age 3 child and maternal RSA self-regulation were measured as mean RSA during a resting task. Results More positive RSA synchrony with children with stronger individual RSA self-regulation predicted greater decreases in harsh parenting. In contrast, more positive RSA synchrony with children with weaker RSA self-regulation predicted greater increases in harsh parenting. In turn, greater increases in harsh parenting were related to greater increases in children's externalizing problems. Conclusions This study illustrates that individual differences in RSA self-regulation influence how parent?child RSA synchrony shapes developmental psychopathology over time and adds to prior research showing that parent?child coregulation patterns may be adaptive or maladaptive depending on the protective or risk-related qualities of the corresponding persons or context. En ligne : https://doi.org/10.1111/jcpp.70001 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571 [article] Mother-preschooler RSA synchrony and self-regulation as antecedents of developmental psychopathology in early childhood [texte imprimé] / Longfeng LI, Auteur ; Sara SUCH, Auteur ; Erika LUNKENHEIMER, Auteur . - p.1724-1735. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1724-1735 Mots-clés : Behavior problems  biomarkers  developmental psychopathology  parenting  parent–child interaction Index. décimale : PER Périodiques Résumé : Background We examined whether mother-preschooler respiratory sinus arrhythmia (RSA) synchrony and self-regulation, as potential biological antecedents of developmental psychopathology, interacted to shape children's later behavior problems directly and indirectly via harsh parenting. Methods Mother-preschooler dyads (N?=?135; 53% female) were oversampled for familial risk. Mother-rated harsh parenting and child behavior problems at ages 3 and 4?years were modeled as latent change scores across ages. Age 3 mother?child RSA synchrony was estimated with multilevel modeling as the concurrent effects of maternal RSA on child RSA during a challenging parent?child task. Age 3 child and maternal RSA self-regulation were measured as mean RSA during a resting task. Results More positive RSA synchrony with children with stronger individual RSA self-regulation predicted greater decreases in harsh parenting. In contrast, more positive RSA synchrony with children with weaker RSA self-regulation predicted greater increases in harsh parenting. In turn, greater increases in harsh parenting were related to greater increases in children's externalizing problems. Conclusions This study illustrates that individual differences in RSA self-regulation influence how parent?child RSA synchrony shapes developmental psychopathology over time and adds to prior research showing that parent?child coregulation patterns may be adaptive or maladaptive depending on the protective or risk-related qualities of the corresponding persons or context. En ligne : https://doi.org/10.1111/jcpp.70001 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571

Capturing change in restricted and repetitive behaviour in preschoolers with ASD: A comparison of direct behavioural observation and parent report / Naisan RAJI in Journal of Child Psychology and Psychiatry, 66-11 (November 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1736-1747 Titre : Capturing change in restricted and repetitive behaviour in preschoolers with ASD: A comparison of direct behavioural observation and parent report Type de document : texte imprimé Auteurs : Naisan RAJI, Auteur ; Janina KITZEROW-CLEVEN, Auteur ; Ziyon KIM, Auteur ; Solvejg K. KLEBER, Auteur ; Leonie POLZER, Auteur ; Christian LEMLER, Auteur ; Melanie RING, Auteur ; Regina TAURINES, Auteur ; Julia GEIßLER, Auteur ; Ulrike FRÖHLICH, Auteur ; Michele NOTERDAEME, Auteur ; Nico BAST, Auteur ; Christine M. FREITAG, Auteur Article en page(s) : p.1736-1747 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  longitudinal studies  development  behavioural measures  stereotyped behaviour Index. décimale : PER Périodiques Résumé : Background Restricted and repetitive behaviour (RRB) in autism spectrum disorder (ASD) can be assessed by different measures, which diverge in item quantity, dimensionality or source of information. However, change sensitivity has not been systematically investigated among commonly used measures, albeit its importance for clinical trials and longitudinal studies. Methods Longitudinal data resulting from behavioural observation (Autism Diagnostic Observation Schedule-2, ADOS-2; Brief Observation of Social Communication Change, BOSCC) and parent report (Restricted Behaviour Scale-Revised, RBS-R) was collected for 134 toddlers and preschoolers aged 25?65?months diagnosed with ASD by the Autism Diagnostic Interview-Revised (ADI-R) and ADOS-2. Change sensitivity was estimated using the reliable-change index and developmental trajectories of RRB by linear mixed models and k-means clustering. Results The RBS-R identified significantly more reliable change in RRB severity compared to ADOS-2 and BOSCC. For all measures, except the RBS-R self-injurious behaviour subscale, three distinct RRB trajectories were found as follows: increasing, stable and decreasing RRB severity. Overlap was low between trajectory group assignment across measures, as were cross-sectional correlations between ADI-R, ADOS-2, BOSCC and RBS-R. Trajectory group comparisons among measures mostly showed lower baseline RRB severity in the increasing trajectory groups and higher baseline RRB severity in the decreasing trajectory groups. The trajectory groups did not differ in age or nonverbal IQ across RRB measures, except for the RBS-R compulsive behaviour subscale, which had higher nonverbal IQ in the decreasing trajectory group. Conclusions The dimensional questionnaire RBS-R compared to ADOS-2 and BOSCC is superior in capturing subtle changes in RRB during preschool age. En ligne : https://doi.org/10.1111/jcpp.70009 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571 [article] Capturing change in restricted and repetitive behaviour in preschoolers with ASD: A comparison of direct behavioural observation and parent report [texte imprimé] / Naisan RAJI, Auteur ; Janina KITZEROW-CLEVEN, Auteur ; Ziyon KIM, Auteur ; Solvejg K. KLEBER, Auteur ; Leonie POLZER, Auteur ; Christian LEMLER, Auteur ; Melanie RING, Auteur ; Regina TAURINES, Auteur ; Julia GEIßLER, Auteur ; Ulrike FRÖHLICH, Auteur ; Michele NOTERDAEME, Auteur ; Nico BAST, Auteur ; Christine M. FREITAG, Auteur . - p.1736-1747. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1736-1747 Mots-clés : Autism spectrum disorders  longitudinal studies  development  behavioural measures  stereotyped behaviour Index. décimale : PER Périodiques Résumé : Background Restricted and repetitive behaviour (RRB) in autism spectrum disorder (ASD) can be assessed by different measures, which diverge in item quantity, dimensionality or source of information. However, change sensitivity has not been systematically investigated among commonly used measures, albeit its importance for clinical trials and longitudinal studies. Methods Longitudinal data resulting from behavioural observation (Autism Diagnostic Observation Schedule-2, ADOS-2; Brief Observation of Social Communication Change, BOSCC) and parent report (Restricted Behaviour Scale-Revised, RBS-R) was collected for 134 toddlers and preschoolers aged 25?65?months diagnosed with ASD by the Autism Diagnostic Interview-Revised (ADI-R) and ADOS-2. Change sensitivity was estimated using the reliable-change index and developmental trajectories of RRB by linear mixed models and k-means clustering. Results The RBS-R identified significantly more reliable change in RRB severity compared to ADOS-2 and BOSCC. For all measures, except the RBS-R self-injurious behaviour subscale, three distinct RRB trajectories were found as follows: increasing, stable and decreasing RRB severity. Overlap was low between trajectory group assignment across measures, as were cross-sectional correlations between ADI-R, ADOS-2, BOSCC and RBS-R. Trajectory group comparisons among measures mostly showed lower baseline RRB severity in the increasing trajectory groups and higher baseline RRB severity in the decreasing trajectory groups. The trajectory groups did not differ in age or nonverbal IQ across RRB measures, except for the RBS-R compulsive behaviour subscale, which had higher nonverbal IQ in the decreasing trajectory group. Conclusions The dimensional questionnaire RBS-R compared to ADOS-2 and BOSCC is superior in capturing subtle changes in RRB during preschool age. En ligne : https://doi.org/10.1111/jcpp.70009 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571

Research Review: Assessment of early-life adversity and trauma – cumulative risk and dimensional approaches / Laura MACHLIN in Journal of Child Psychology and Psychiatry, 66-11 (November 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1748-1764 Titre : Research Review: Assessment of early-life adversity and trauma – cumulative risk and dimensional approaches Type de document : texte imprimé Auteurs : Laura MACHLIN, Auteur ; Margaret A. SHERIDAN, Auteur ; Angelina Pei-Tzu TSAI, Auteur ; Katie A. MCLAUGHLIN, Auteur Article en page(s) : p.1748-1764 Langues : Anglais (eng) Mots-clés : Early-life adversity  assessment  cumulative risk  dimensional models  threat  deprivation Index. décimale : PER Périodiques Résumé : In this research review, we present approaches and recommendations for assessing early-life adversity and childhood trauma aligned with two leading conceptual models of adversity: cumulative risk and dimensional models. We summarize the measurement implications of each conceptual model and common approaches for assessing early-life adversity in studies utilizing each of these models. We consider other critical components in the assessment of early-life adversity and trauma, including retrospective and prospective reporting, objective and subjective measurement, and caregiver and child reporting. Finally, we briefly summarize the existing interview and questionnaire measures that are widely used to assess early-life adversity and trauma using both cumulative risk and dimensional approaches. This work suggests that there is greater heterogeneity in measures used to assess the dimensional model relative to those used to assess the cumulative risk model, which allows for more flexibility in the assessment of early-life adversity. In addition, we observed that more detailed measures were available to assess experiences of threat compared to experiences of deprivation. Measures that assess adversity experiences in terms of frequency and severity across multiple dimensions of experience within a single measure are needed to facilitate consistent and reliable assessment of early-life adversity and trauma, particularly when applying dimensional models. En ligne : https://doi.org/10.1111/jcpp.14170 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571 [article] Research Review: Assessment of early-life adversity and trauma – cumulative risk and dimensional approaches [texte imprimé] / Laura MACHLIN, Auteur ; Margaret A. SHERIDAN, Auteur ; Angelina Pei-Tzu TSAI, Auteur ; Katie A. MCLAUGHLIN, Auteur . - p.1748-1764. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1748-1764 Mots-clés : Early-life adversity  assessment  cumulative risk  dimensional models  threat  deprivation Index. décimale : PER Périodiques Résumé : In this research review, we present approaches and recommendations for assessing early-life adversity and childhood trauma aligned with two leading conceptual models of adversity: cumulative risk and dimensional models. We summarize the measurement implications of each conceptual model and common approaches for assessing early-life adversity in studies utilizing each of these models. We consider other critical components in the assessment of early-life adversity and trauma, including retrospective and prospective reporting, objective and subjective measurement, and caregiver and child reporting. Finally, we briefly summarize the existing interview and questionnaire measures that are widely used to assess early-life adversity and trauma using both cumulative risk and dimensional approaches. This work suggests that there is greater heterogeneity in measures used to assess the dimensional model relative to those used to assess the cumulative risk model, which allows for more flexibility in the assessment of early-life adversity. In addition, we observed that more detailed measures were available to assess experiences of threat compared to experiences of deprivation. Measures that assess adversity experiences in terms of frequency and severity across multiple dimensions of experience within a single measure are needed to facilitate consistent and reliable assessment of early-life adversity and trauma, particularly when applying dimensional models. En ligne : https://doi.org/10.1111/jcpp.14170 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571

Research Review: Conceptualizing and measuring ‘problem behavior’ in early intervention autism research – a project AIM secondary systematic review / Kristen BOTTEMA-BEUTEL in Journal of Child Psychology and Psychiatry, 66-11 (November 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1765-1780 Titre : Research Review: Conceptualizing and measuring ‘problem behavior’ in early intervention autism research – a project AIM secondary systematic review Type de document : texte imprimé Auteurs : Kristen BOTTEMA-BEUTEL, Auteur ; Ruoxi GUO, Auteur ; Jessica HINSON-WILIAMS, Auteur ; Yueyang SHEN, Auteur ; Shannon LAPOINT, Auteur ; Tiffany WOYNAROSKI, Auteur ; Micheal SANDBANK, Auteur Article en page(s) : p.1765-1780 Langues : Anglais (eng) Mots-clés : Problem behavior  restrictive and repetitive behavior  autism  early intervention  treatment  measurement Index. décimale : PER Périodiques Résumé : Background Some autistic children exhibit behavior that caregivers, clinicians, and researchers consider problematic. However, there is little consensus about the types of behaviors that should be treated as a problem and reduced via intervention. In autism intervention research, problem behaviors range from inherently harmful behaviors such as aggression and self-injury to nonnormative but not harmful behaviors associated with autism such as repetitive movements. Likewise, there are a variety of conceptualizations and measurement practices used to assess these behaviors. Methods In this secondary systematic review of group-design, nonpharmacological intervention studies for autistic children up to age eight, we explore researchers' conceptualizations of problem behavior and measurement systems to assess problem behavior. We defined problem behavior as any outcome where behaviors were targeted for reduction or elimination. A coding scheme was applied to 102 studies that met inclusion criteria for the secondary review. All studies were double coded by two independent coders. Results Sixty-two percent of studies described reducing behavior as a primary or secondary purpose of the study and/or intervention, 33% gave a rationale for targeting behaviors for reduction, and 28% offered a conceptualization of the behavior(s) they targeted. Only 8% offered a conceptual definition. The most common measures were ?off-the-shelf? measures that had undergone at least some previous validation beyond interrater reliability and that involved parent reports. For the 10 most common assessment measures, two were validated along six different validation dimensions in autistic populations. All but one full scale or subscale measured behaviors that were nonnormative but not inherently harmful, or a mix of behaviors that were inherently harmful and that were nonnormative but not inherently harmful. Conclusions Intervention researchers should provide clear definitions and rationales for targeting behaviors for reduction via intervention and should develop refined measurement tools for assessing these behaviors in collaboration with the autistic community. En ligne : https://doi.org/10.1111/jcpp.14177 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571 [article] Research Review: Conceptualizing and measuring ‘problem behavior’ in early intervention autism research – a project AIM secondary systematic review [texte imprimé] / Kristen BOTTEMA-BEUTEL, Auteur ; Ruoxi GUO, Auteur ; Jessica HINSON-WILIAMS, Auteur ; Yueyang SHEN, Auteur ; Shannon LAPOINT, Auteur ; Tiffany WOYNAROSKI, Auteur ; Micheal SANDBANK, Auteur . - p.1765-1780. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-11 (November 2025) . - p.1765-1780 Mots-clés : Problem behavior  restrictive and repetitive behavior  autism  early intervention  treatment  measurement Index. décimale : PER Périodiques Résumé : Background Some autistic children exhibit behavior that caregivers, clinicians, and researchers consider problematic. However, there is little consensus about the types of behaviors that should be treated as a problem and reduced via intervention. In autism intervention research, problem behaviors range from inherently harmful behaviors such as aggression and self-injury to nonnormative but not harmful behaviors associated with autism such as repetitive movements. Likewise, there are a variety of conceptualizations and measurement practices used to assess these behaviors. Methods In this secondary systematic review of group-design, nonpharmacological intervention studies for autistic children up to age eight, we explore researchers' conceptualizations of problem behavior and measurement systems to assess problem behavior. We defined problem behavior as any outcome where behaviors were targeted for reduction or elimination. A coding scheme was applied to 102 studies that met inclusion criteria for the secondary review. All studies were double coded by two independent coders. Results Sixty-two percent of studies described reducing behavior as a primary or secondary purpose of the study and/or intervention, 33% gave a rationale for targeting behaviors for reduction, and 28% offered a conceptualization of the behavior(s) they targeted. Only 8% offered a conceptual definition. The most common measures were ?off-the-shelf? measures that had undergone at least some previous validation beyond interrater reliability and that involved parent reports. For the 10 most common assessment measures, two were validated along six different validation dimensions in autistic populations. All but one full scale or subscale measured behaviors that were nonnormative but not inherently harmful, or a mix of behaviors that were inherently harmful and that were nonnormative but not inherently harmful. Conclusions Intervention researchers should provide clear definitions and rationales for targeting behaviors for reduction via intervention and should develop refined measurement tools for assessing these behaviors in collaboration with the autistic community. En ligne : https://doi.org/10.1111/jcpp.14177 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=571