Dépouillements

Infant Neural Sensitivity to Dynamic Eye Gaze Relates to Quality of Parent–Infant Interaction at 7-Months in Infants at Risk for Autism / Mayada ELSABBAGH in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.283-291 Titre : Infant Neural Sensitivity to Dynamic Eye Gaze Relates to Quality of Parent–Infant Interaction at 7-Months in Infants at Risk for Autism Type de document : Texte imprimé et/ou numérique Auteurs : Mayada ELSABBAGH, Auteur ; Ruth BRUNO, Auteur ; Ming Wai WAN, Auteur ; Tony CHARMAN, Auteur ; Mark H. JOHNSON, Auteur ; Jonathan GREEN, Auteur Article en page(s) : p.283-291 Langues : Anglais (eng) Mots-clés : Infant  Autism  Interaction  EEG  Familial risk  Prospective study Index. décimale : PER Périodiques Résumé : Links between brain function measures and quality of parent–child interactions within the early developmental period have been investigated in typical and atypical development. We examined such links in a group of 104 infants with and without a family history for autism in the first year of life. Our findings suggest robust associations between event related potential responses to eye gaze and observed parent–infant interaction measures. In both groups, infants with more positive affect exhibit stronger differentiation to gaze stimuli. This association was observed with the earlier P100 waveform component in the control group but with the later P400 component in infants at-risk. These exploratory findings are critical in paving the way for a better understanding of how infant laboratory measures may relate to overt behavior and how both can be combined in the context of predicting risk or clinical diagnosis in toddlerhood. En ligne : http://dx.doi.org/10.1007/s10803-014-2192-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Infant Neural Sensitivity to Dynamic Eye Gaze Relates to Quality of Parent–Infant Interaction at 7-Months in Infants at Risk for Autism [Texte imprimé et/ou numérique] / Mayada ELSABBAGH, Auteur ; Ruth BRUNO, Auteur ; Ming Wai WAN, Auteur ; Tony CHARMAN, Auteur ; Mark H. JOHNSON, Auteur ; Jonathan GREEN, Auteur . - p.283-291. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.283-291 Mots-clés : Infant  Autism  Interaction  EEG  Familial risk  Prospective study Index. décimale : PER Périodiques Résumé : Links between brain function measures and quality of parent–child interactions within the early developmental period have been investigated in typical and atypical development. We examined such links in a group of 104 infants with and without a family history for autism in the first year of life. Our findings suggest robust associations between event related potential responses to eye gaze and observed parent–infant interaction measures. In both groups, infants with more positive affect exhibit stronger differentiation to gaze stimuli. This association was observed with the earlier P100 waveform component in the control group but with the later P400 component in infants at-risk. These exploratory findings are critical in paving the way for a better understanding of how infant laboratory measures may relate to overt behavior and how both can be combined in the context of predicting risk or clinical diagnosis in toddlerhood. En ligne : http://dx.doi.org/10.1007/s10803-014-2192-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Atypical Laterality of Resting Gamma Oscillations in Autism Spectrum Disorders / Christina R. MAXWELL in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.292-297 Titre : Atypical Laterality of Resting Gamma Oscillations in Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Christina R. MAXWELL, Auteur ; Michele E. VILLALOBOS, Auteur ; Robert T. SCHULTZ, Auteur ; Beate HERPERTZ-DAHLMANN, Auteur ; Kerstin KONRAD, Auteur ; Gregor KOHLS, Auteur Article en page(s) : p.292-297 Langues : Anglais (eng) Mots-clés : Autism  Gamma  EEG  SRS  Resting state  Laterality Index. décimale : PER Périodiques Résumé : Abnormal brain oscillatory activity has been found in autism spectrum disorders (ASD) and proposed as a potential biomarker. While several studies have investigated gamma oscillations in ASD, none have examined resting gamma power across multiple brain regions. This study investigated resting gamma power using EEG in 15 boys with ASD and 18 age and intelligence quotient matched typically developing controls. We found a decrease in resting gamma power at right lateral electrodes in ASD. We further explored associations between gamma and ASD severity as measured by the Social Responsiveness Scale (SRS) and found a negative correlation between SRS and gamma power. We believe that our findings give further support of gamma oscillations as a potential biomarker for ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1842-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Atypical Laterality of Resting Gamma Oscillations in Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Christina R. MAXWELL, Auteur ; Michele E. VILLALOBOS, Auteur ; Robert T. SCHULTZ, Auteur ; Beate HERPERTZ-DAHLMANN, Auteur ; Kerstin KONRAD, Auteur ; Gregor KOHLS, Auteur . - p.292-297. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.292-297 Mots-clés : Autism  Gamma  EEG  SRS  Resting state  Laterality Index. décimale : PER Périodiques Résumé : Abnormal brain oscillatory activity has been found in autism spectrum disorders (ASD) and proposed as a potential biomarker. While several studies have investigated gamma oscillations in ASD, none have examined resting gamma power across multiple brain regions. This study investigated resting gamma power using EEG in 15 boys with ASD and 18 age and intelligence quotient matched typically developing controls. We found a decrease in resting gamma power at right lateral electrodes in ASD. We further explored associations between gamma and ASD severity as measured by the Social Responsiveness Scale (SRS) and found a negative correlation between SRS and gamma power. We believe that our findings give further support of gamma oscillations as a potential biomarker for ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1842-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Atypical Neurophysiology Underlying Episodic and Semantic Memory in Adults with Autism Spectrum Disorder / Esha MASSAND in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.298-315 Titre : Atypical Neurophysiology Underlying Episodic and Semantic Memory in Adults with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Esha MASSAND, Auteur ; Dermot M. BOWLER, Auteur Article en page(s) : p.298-315 Langues : Anglais (eng) Mots-clés : Memory  Episodic  Semantic  Source memory  Autism spectrum disorder  Event-related potential Index. décimale : PER Périodiques Résumé : Individuals with autism spectrum disorder (ASD) show atypicalities in episodic memory (Boucher et al. in Psychological Bulletin, 138 (3), 458–496, 2012). We asked participants to recall the colours of a set of studied line drawings (episodic judgement), or to recognize line drawings alone (semantic judgement). Cycowicz et al. (Journal of Experimental Child Psychology, 65, 171–237, 2001) found early (300 ms onset) posterior old–new event-related potential effects for semantic judgements in typically developing (TD) individuals, and occipitally focused negativity (800 ms onset) for episodic judgements. Our results replicated findings in TD individuals and demonstrate attenuated early old–new effects in ASD. Late posterior negativity was present in the ASD group, but was not specific to this time window. This non-specificity may contribute to the atypical episodic memory judgements characteristic of individuals with ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1869-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Atypical Neurophysiology Underlying Episodic and Semantic Memory in Adults with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Esha MASSAND, Auteur ; Dermot M. BOWLER, Auteur . - p.298-315. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.298-315 Mots-clés : Memory  Episodic  Semantic  Source memory  Autism spectrum disorder  Event-related potential Index. décimale : PER Périodiques Résumé : Individuals with autism spectrum disorder (ASD) show atypicalities in episodic memory (Boucher et al. in Psychological Bulletin, 138 (3), 458–496, 2012). We asked participants to recall the colours of a set of studied line drawings (episodic judgement), or to recognize line drawings alone (semantic judgement). Cycowicz et al. (Journal of Experimental Child Psychology, 65, 171–237, 2001) found early (300 ms onset) posterior old–new event-related potential effects for semantic judgements in typically developing (TD) individuals, and occipitally focused negativity (800 ms onset) for episodic judgements. Our results replicated findings in TD individuals and demonstrate attenuated early old–new effects in ASD. Late posterior negativity was present in the ASD group, but was not specific to this time window. This non-specificity may contribute to the atypical episodic memory judgements characteristic of individuals with ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1869-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Measuring the Plasticity of Social Approach: A Randomized Controlled Trial of the Effects of the PEERS Intervention on EEG Asymmetry in Adolescents with Autism Spectrum Disorders / Amy Vaughan VAN HECKE in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.316-335 Titre : Measuring the Plasticity of Social Approach: A Randomized Controlled Trial of the Effects of the PEERS Intervention on EEG Asymmetry in Adolescents with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Amy Vaughan VAN HECKE, Auteur ; Sheryl STEVENS, Auteur ; Audrey M. CARSON, Auteur ; Jeffrey S. KARST, Auteur ; Bridget DOLAN, Auteur ; Kirsten SCHOHL, Auteur ; Ryan J. MCKINDLES, Auteur ; Rheanna REMMEL, Auteur ; Scott BROCKMAN, Auteur Article en page(s) : p.316-335 Langues : Anglais (eng) Mots-clés : Autism  Adolescence  EEG  Asymmetry  PEERS  Intervention  Brain  Plasticity Index. décimale : PER Périodiques Résumé : This study examined whether the Program for the Education and Enrichment of Relational Skills (PEERS: Social skills for teenagers with developmental and autism spectrum disorders: The PEERS treatment manual, Routledge, New York, 2010a) affected neural function, via EEG asymmetry, in a randomized controlled trial of adolescents with Autism spectrum disorders (ASD) and a group of typically developing adolescents. Adolescents with ASD in PEERS shifted from right-hemisphere gamma-band EEG asymmetry before PEERS to left-hemisphere EEG asymmetry after PEERS, versus a waitlist ASD group. Left-hemisphere EEG asymmetry was associated with more social contacts and knowledge, and fewer symptoms of autism. Adolescents with ASD in PEERS no longer differed from typically developing adolescents in left-dominant EEG asymmetry at post-test. These findings are discussed via the Modifier Model of Autism (Mundy et al. in Res Pract Persons Severe Disabl 32(2):124, 2007), with emphasis on remediating isolation/withdrawal in ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1883-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Measuring the Plasticity of Social Approach: A Randomized Controlled Trial of the Effects of the PEERS Intervention on EEG Asymmetry in Adolescents with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Amy Vaughan VAN HECKE, Auteur ; Sheryl STEVENS, Auteur ; Audrey M. CARSON, Auteur ; Jeffrey S. KARST, Auteur ; Bridget DOLAN, Auteur ; Kirsten SCHOHL, Auteur ; Ryan J. MCKINDLES, Auteur ; Rheanna REMMEL, Auteur ; Scott BROCKMAN, Auteur . - p.316-335. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.316-335 Mots-clés : Autism  Adolescence  EEG  Asymmetry  PEERS  Intervention  Brain  Plasticity Index. décimale : PER Périodiques Résumé : This study examined whether the Program for the Education and Enrichment of Relational Skills (PEERS: Social skills for teenagers with developmental and autism spectrum disorders: The PEERS treatment manual, Routledge, New York, 2010a) affected neural function, via EEG asymmetry, in a randomized controlled trial of adolescents with Autism spectrum disorders (ASD) and a group of typically developing adolescents. Adolescents with ASD in PEERS shifted from right-hemisphere gamma-band EEG asymmetry before PEERS to left-hemisphere EEG asymmetry after PEERS, versus a waitlist ASD group. Left-hemisphere EEG asymmetry was associated with more social contacts and knowledge, and fewer symptoms of autism. Adolescents with ASD in PEERS no longer differed from typically developing adolescents in left-dominant EEG asymmetry at post-test. These findings are discussed via the Modifier Model of Autism (Mundy et al. in Res Pract Persons Severe Disabl 32(2):124, 2007), with emphasis on remediating isolation/withdrawal in ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1883-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Resting and Task-Modulated High-Frequency Brain Rhythms Measured by Scalp Encephalography in Infants with Tuberous Sclerosis Complex / Catherine STAMOULIS in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.336-353 Titre : Resting and Task-Modulated High-Frequency Brain Rhythms Measured by Scalp Encephalography in Infants with Tuberous Sclerosis Complex Type de document : Texte imprimé et/ou numérique Auteurs : Catherine STAMOULIS, Auteur ; Vanessa VOGEL-FARLEY, Auteur ; Geneva DEGREGORIO, Auteur ; Shafali S. JESTE, Auteur ; Charles A. NELSON, Auteur Article en page(s) : p.336-353 Langues : Anglais (eng) Mots-clés : Tuberous sclerosis complex  Brain dynamics  EEG  Dominant brain rhythms Index. décimale : PER Périodiques Résumé : The electrophysiological correlates of cognitive deficits in tuberous sclerosis complex (TSC) are not well understood, and modulations of neural dynamics by neuroanatomical abnormalities that characterize the disorder remain elusive. Neural oscillations (rhythms) are a fundamental aspect of brain function, and have dominant frequencies in a wide frequency range. The spatio-temporal dynamics of these frequencies in TSC are currently unknown. Using a novel signal decomposition approach this study investigated dominant cortical frequencies in 10 infants with TSC, in the age range 18–30 months, and 12 age-matched healthy controls. Distinct spectral characteristics were estimated in the two groups. High-frequency [in the high-gamma (>50 Hz) and ripple (>80 Hz) ranges], non-random EEG components were identified in both TSC and healthy infants at 18 months. Additional components in the lower gamma (30–50 Hz) ranges were also identified, with higher characteristic frequencies in TSC than in controls. Lower frequencies were statistically identical in both sub-groups. A significant shift in the high-frequency spectral content of the EEG was observed as a function of age, independently of task performance, possibly reflecting an overall maturation of developing neural circuits. This shift occurred earlier in healthy infants than in TSC, i.e., by age 20 months the highest dominant frequencies were in the high gamma range, whereas in TSC dominant frequencies above 100 Hz were still measurable. At age 28–30 months a statistically significant decrease in dominant high frequencies was observed in both TSC and healthy infants, possibly reflecting increased myelination and neuronal connection strengthening with age. Although based on small samples, and thus preliminary, the findings in this study suggest that dominant cortical rhythms, a fundamental aspect of neurodynamics, may be affected in TSC, possibly leading to impaired information processing in the brain. En ligne : http://dx.doi.org/10.1007/s10803-013-1887-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Resting and Task-Modulated High-Frequency Brain Rhythms Measured by Scalp Encephalography in Infants with Tuberous Sclerosis Complex [Texte imprimé et/ou numérique] / Catherine STAMOULIS, Auteur ; Vanessa VOGEL-FARLEY, Auteur ; Geneva DEGREGORIO, Auteur ; Shafali S. JESTE, Auteur ; Charles A. NELSON, Auteur . - p.336-353. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.336-353 Mots-clés : Tuberous sclerosis complex  Brain dynamics  EEG  Dominant brain rhythms Index. décimale : PER Périodiques Résumé : The electrophysiological correlates of cognitive deficits in tuberous sclerosis complex (TSC) are not well understood, and modulations of neural dynamics by neuroanatomical abnormalities that characterize the disorder remain elusive. Neural oscillations (rhythms) are a fundamental aspect of brain function, and have dominant frequencies in a wide frequency range. The spatio-temporal dynamics of these frequencies in TSC are currently unknown. Using a novel signal decomposition approach this study investigated dominant cortical frequencies in 10 infants with TSC, in the age range 18–30 months, and 12 age-matched healthy controls. Distinct spectral characteristics were estimated in the two groups. High-frequency [in the high-gamma (>50 Hz) and ripple (>80 Hz) ranges], non-random EEG components were identified in both TSC and healthy infants at 18 months. Additional components in the lower gamma (30–50 Hz) ranges were also identified, with higher characteristic frequencies in TSC than in controls. Lower frequencies were statistically identical in both sub-groups. A significant shift in the high-frequency spectral content of the EEG was observed as a function of age, independently of task performance, possibly reflecting an overall maturation of developing neural circuits. This shift occurred earlier in healthy infants than in TSC, i.e., by age 20 months the highest dominant frequencies were in the high gamma range, whereas in TSC dominant frequencies above 100 Hz were still measurable. At age 28–30 months a statistically significant decrease in dominant high frequencies was observed in both TSC and healthy infants, possibly reflecting increased myelination and neuronal connection strengthening with age. Although based on small samples, and thus preliminary, the findings in this study suggest that dominant cortical rhythms, a fundamental aspect of neurodynamics, may be affected in TSC, possibly leading to impaired information processing in the brain. En ligne : http://dx.doi.org/10.1007/s10803-013-1887-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Electromyographic Responses to Emotional Facial Expressions in 6–7 Year Olds with Autism Spectrum Disorders / P. K. H. DESCHAMPS in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.354-362 Titre : Electromyographic Responses to Emotional Facial Expressions in 6–7 Year Olds with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : P. K. H. DESCHAMPS, Auteur ; L. COPPES, Auteur ; J. L. KENEMANS, Auteur ; D. J. L. G. SCHUTTER, Auteur ; W. MATTHYS, Auteur Article en page(s) : p.354-362 Langues : Anglais (eng) Mots-clés : Children  Emotional responsiveness  Facial mimicry  ASD Index. décimale : PER Périodiques Résumé : This study aimed to examine facial mimicry in 6–7 year old children with autism spectrum disorder (ASD) and to explore whether facial mimicry was related to the severity of impairment in social responsiveness. Facial electromyographic activity in response to angry, fearful, sad and happy facial expressions was recorded in twenty 6–7 year old children with ASD and twenty-seven typically developing children. Even though results did not show differences in facial mimicry between children with ASD and typically developing children, impairment in social responsiveness was significantly associated with reduced fear mimicry in children with ASD. These findings demonstrate normal mimicry in children with ASD as compared to healthy controls, but that in children with ASD the degree of impairments in social responsiveness may be associated with reduced sensitivity to distress signals. En ligne : http://dx.doi.org/10.1007/s10803-013-1890-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Electromyographic Responses to Emotional Facial Expressions in 6–7 Year Olds with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / P. K. H. DESCHAMPS, Auteur ; L. COPPES, Auteur ; J. L. KENEMANS, Auteur ; D. J. L. G. SCHUTTER, Auteur ; W. MATTHYS, Auteur . - p.354-362. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.354-362 Mots-clés : Children  Emotional responsiveness  Facial mimicry  ASD Index. décimale : PER Périodiques Résumé : This study aimed to examine facial mimicry in 6–7 year old children with autism spectrum disorder (ASD) and to explore whether facial mimicry was related to the severity of impairment in social responsiveness. Facial electromyographic activity in response to angry, fearful, sad and happy facial expressions was recorded in twenty 6–7 year old children with ASD and twenty-seven typically developing children. Even though results did not show differences in facial mimicry between children with ASD and typically developing children, impairment in social responsiveness was significantly associated with reduced fear mimicry in children with ASD. These findings demonstrate normal mimicry in children with ASD as compared to healthy controls, but that in children with ASD the degree of impairments in social responsiveness may be associated with reduced sensitivity to distress signals. En ligne : http://dx.doi.org/10.1007/s10803-013-1890-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

An Electrophysiological Investigation of Interhemispheric Transfer Time in Children and Adolescents with High-Functioning Autism Spectrum Disorders / Ann CLAWSON in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.363-375 Titre : An Electrophysiological Investigation of Interhemispheric Transfer Time in Children and Adolescents with High-Functioning Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Ann CLAWSON, Auteur ; Peter E. CLAYSON, Auteur ; Mikle SOUTH, Auteur ; Erin D. BIGLER, Auteur ; Michael J. LARSON, Auteur Article en page(s) : p.363-375 Langues : Anglais (eng) Mots-clés : Autism  Interhemispheric transfer time  N1  P1  Event-related potential  Corpus callosum  White matter Index. décimale : PER Périodiques Résumé : Little is known about the functional impact of putative deficits in white-matter connectivity across the corpus callosum (CC) in individuals with autism spectrum disorders (ASDs). We utilized the temporal sensitivity of event-related potentials to examine the interhemispheric transfer time (IHTT) of basic visual information across the CC in youth with high-functioning ASD relative to healthy controls. We conducted two experiments: a visual letter matching experiment (n = 46) and a visual picture matching experiment, (n = 48) and utilized both electrophysiological (N1 and P1 amplitudes and latencies) and behavioral [response times (RTs), error rates] indices of IHTT. There were no significant group differences on either experiment for RTs, error rates, or N1 and P1 latencies, suggesting that on basic tasks the timing of information flow across the CC may not be altered in high functioning ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1895-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] An Electrophysiological Investigation of Interhemispheric Transfer Time in Children and Adolescents with High-Functioning Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Ann CLAWSON, Auteur ; Peter E. CLAYSON, Auteur ; Mikle SOUTH, Auteur ; Erin D. BIGLER, Auteur ; Michael J. LARSON, Auteur . - p.363-375. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.363-375 Mots-clés : Autism  Interhemispheric transfer time  N1  P1  Event-related potential  Corpus callosum  White matter Index. décimale : PER Périodiques Résumé : Little is known about the functional impact of putative deficits in white-matter connectivity across the corpus callosum (CC) in individuals with autism spectrum disorders (ASDs). We utilized the temporal sensitivity of event-related potentials to examine the interhemispheric transfer time (IHTT) of basic visual information across the CC in youth with high-functioning ASD relative to healthy controls. We conducted two experiments: a visual letter matching experiment (n = 46) and a visual picture matching experiment, (n = 48) and utilized both electrophysiological (N1 and P1 amplitudes and latencies) and behavioral [response times (RTs), error rates] indices of IHTT. There were no significant group differences on either experiment for RTs, error rates, or N1 and P1 latencies, suggesting that on basic tasks the timing of information flow across the CC may not be altered in high functioning ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1895-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Eyeblink Conditioning: A Non-invasive Biomarker for Neurodevelopmental Disorders / Bethany C. REEB-SUTHERLAND in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.376-394 Titre : Eyeblink Conditioning: A Non-invasive Biomarker for Neurodevelopmental Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Bethany C. REEB-SUTHERLAND, Auteur ; Nathan A. FOX, Auteur Article en page(s) : p.376-394 Langues : Anglais (eng) Mots-clés : Eyeblink conditioning  Neurodevelopmental disorders  Autism spectrum disorder  Associative learning  Cerebellum Index. décimale : PER Périodiques Résumé : Eyeblink conditioning (EBC) is a classical conditioning paradigm typically used to study the underlying neural processes of learning and memory. EBC has a well-defined neural circuitry, is non-invasive, and can be employed in human infants shortly after birth making it an ideal tool to use in both developing and special populations. In addition, abnormalities in the cerebellum, a region of the brain highly involved in EBC, have been implicated in a number of neurodevelopmental disorders including autism spectrum disorders (ASDs). In the current paper, we review studies that have employed EBC as a biomarker for several neurodevelopmental disorders including fetal alcohol syndrome, Down syndrome, fragile X syndrome, attention deficit/hyperactivity disorder, dyslexia, specific language impairment, and schizophrenia. In addition, we discuss the benefits of using such a tool in individuals with ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1905-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Eyeblink Conditioning: A Non-invasive Biomarker for Neurodevelopmental Disorders [Texte imprimé et/ou numérique] / Bethany C. REEB-SUTHERLAND, Auteur ; Nathan A. FOX, Auteur . - p.376-394. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.376-394 Mots-clés : Eyeblink conditioning  Neurodevelopmental disorders  Autism spectrum disorder  Associative learning  Cerebellum Index. décimale : PER Périodiques Résumé : Eyeblink conditioning (EBC) is a classical conditioning paradigm typically used to study the underlying neural processes of learning and memory. EBC has a well-defined neural circuitry, is non-invasive, and can be employed in human infants shortly after birth making it an ideal tool to use in both developing and special populations. In addition, abnormalities in the cerebellum, a region of the brain highly involved in EBC, have been implicated in a number of neurodevelopmental disorders including autism spectrum disorders (ASDs). In the current paper, we review studies that have employed EBC as a biomarker for several neurodevelopmental disorders including fetal alcohol syndrome, Down syndrome, fragile X syndrome, attention deficit/hyperactivity disorder, dyslexia, specific language impairment, and schizophrenia. In addition, we discuss the benefits of using such a tool in individuals with ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1905-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Neuromagnetic Oscillations Predict Evoked-Response Latency Delays and Core Language Deficits in Autism Spectrum Disorders / J. Christopher EDGAR in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.395-405 Titre : Neuromagnetic Oscillations Predict Evoked-Response Latency Delays and Core Language Deficits in Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : J. Christopher EDGAR, Auteur ; Sarah Y. KHAN, Auteur ; Lisa BLASKEY, Auteur ; Vivian Y. CHOW, Auteur ; Michael REY, Auteur ; William GAETZ, Auteur ; Katelyn M. CANNON, Auteur ; Justin F. MONROE, Auteur ; Lauren CORNEW, Auteur ; Saba QASMIEH, Auteur ; Song LIU, Auteur ; John P. WELSH, Auteur ; Susan E. LEVY, Auteur ; Timothy P. L. ROBERTS, Auteur Article en page(s) : p.395-405 Langues : Anglais (eng) Mots-clés : Auditory  Autism spectrum disorders  M100  Gamma  Evoked  Inter-trial coherence  Phase-locking  Magnetoencephalography Index. décimale : PER Périodiques Résumé : Previous studies have observed evoked response latency as well as gamma band superior temporal gyrus (STG) auditory abnormalities in individuals with autism spectrum disorders (ASD). A limitation of these studies is that associations between these two abnormalities, as well as the full extent of oscillatory phenomena in ASD in terms of frequency and time, have not been examined. Subjects were presented pure tones at 200, 300, 500, and 1,000 Hz while magnetoencephalography assessed activity in STG auditory areas in a sample of 105 children with ASD and 36 typically developing controls (TD). Findings revealed a profile such that auditory STG processes in ASD were characterized by pre-stimulus abnormalities across multiple frequencies, then early high-frequency abnormalities followed by low-frequency abnormalities. Increased pre-stimulus activity was a ‘core’ abnormality, with pre-stimulus activity predicting post-stimulus neural abnormalities, group membership, and clinical symptoms (CELF-4 Core Language Index). Deficits in synaptic integration in the auditory cortex are associated with oscillatory abnormalities in ASD as well as patient symptoms. Increased pre-stimulus activity in ASD likely demonstrates a fundamental signal-to-noise deficit in individuals with ASD, with elevations in oscillatory activity suggesting an inability to maintain an appropriate ‘neural tone’ and an inability to rapidly return to a resting state prior to the next stimulus. En ligne : http://dx.doi.org/10.1007/s10803-013-1904-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Neuromagnetic Oscillations Predict Evoked-Response Latency Delays and Core Language Deficits in Autism Spectrum Disorders [Texte imprimé et/ou numérique] / J. Christopher EDGAR, Auteur ; Sarah Y. KHAN, Auteur ; Lisa BLASKEY, Auteur ; Vivian Y. CHOW, Auteur ; Michael REY, Auteur ; William GAETZ, Auteur ; Katelyn M. CANNON, Auteur ; Justin F. MONROE, Auteur ; Lauren CORNEW, Auteur ; Saba QASMIEH, Auteur ; Song LIU, Auteur ; John P. WELSH, Auteur ; Susan E. LEVY, Auteur ; Timothy P. L. ROBERTS, Auteur . - p.395-405. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.395-405 Mots-clés : Auditory  Autism spectrum disorders  M100  Gamma  Evoked  Inter-trial coherence  Phase-locking  Magnetoencephalography Index. décimale : PER Périodiques Résumé : Previous studies have observed evoked response latency as well as gamma band superior temporal gyrus (STG) auditory abnormalities in individuals with autism spectrum disorders (ASD). A limitation of these studies is that associations between these two abnormalities, as well as the full extent of oscillatory phenomena in ASD in terms of frequency and time, have not been examined. Subjects were presented pure tones at 200, 300, 500, and 1,000 Hz while magnetoencephalography assessed activity in STG auditory areas in a sample of 105 children with ASD and 36 typically developing controls (TD). Findings revealed a profile such that auditory STG processes in ASD were characterized by pre-stimulus abnormalities across multiple frequencies, then early high-frequency abnormalities followed by low-frequency abnormalities. Increased pre-stimulus activity was a ‘core’ abnormality, with pre-stimulus activity predicting post-stimulus neural abnormalities, group membership, and clinical symptoms (CELF-4 Core Language Index). Deficits in synaptic integration in the auditory cortex are associated with oscillatory abnormalities in ASD as well as patient symptoms. Increased pre-stimulus activity in ASD likely demonstrates a fundamental signal-to-noise deficit in individuals with ASD, with elevations in oscillatory activity suggesting an inability to maintain an appropriate ‘neural tone’ and an inability to rapidly return to a resting state prior to the next stimulus. En ligne : http://dx.doi.org/10.1007/s10803-013-1904-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

QEEG Spectral and Coherence Assessment of Autistic Children in Three Different Experimental Conditions / Calixto MACHADO in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.406-424 Titre : QEEG Spectral and Coherence Assessment of Autistic Children in Three Different Experimental Conditions Type de document : Texte imprimé et/ou numérique Auteurs : Calixto MACHADO, Auteur ; Mario ESTÉVEZ, Auteur ; Gerry LEISMAN, Auteur ; Robert MELILLO, Auteur ; Rafael RODRÍGUEZ, Auteur ; Phillip DEFINA, Auteur ; Adrián HERNÁNDEZ, Auteur ; Jesús PÉREZ-NELLAR, Auteur ; Rolando NARANJO, Auteur ; Mauricio CHINCHILLA, Auteur ; Nicolás GARÓFALO, Auteur ; José VARGAS, Auteur ; Carlos BELTRÁN, Auteur Article en page(s) : p.406-424 Langues : Anglais (eng) Mots-clés : Autism  Autism spectrum disorder  EEG  QEEG Index. décimale : PER Périodiques Résumé : We studied autistics by quantitative EEG spectral and coherence analysis during three experimental conditions: basal, watching a cartoon with audio (V–A), and with muted audio band (VwA). Significant reductions were found for the absolute power spectral density (PSD) in the central region for delta and theta, and in the posterior region for sigma and beta bands, lateralized to the right hemisphere. When comparing VwA versus the V–A in the midline regions, we found significant decrements of absolute PSD for delta, theta and alpha, and increments for the beta and gamma bands. In autistics, VwA versus V–A tended to show lower coherence values in the right hemisphere. An impairment of visual and auditory sensory integration in autistics might explain our results. En ligne : http://dx.doi.org/10.1007/s10803-013-1909-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] QEEG Spectral and Coherence Assessment of Autistic Children in Three Different Experimental Conditions [Texte imprimé et/ou numérique] / Calixto MACHADO, Auteur ; Mario ESTÉVEZ, Auteur ; Gerry LEISMAN, Auteur ; Robert MELILLO, Auteur ; Rafael RODRÍGUEZ, Auteur ; Phillip DEFINA, Auteur ; Adrián HERNÁNDEZ, Auteur ; Jesús PÉREZ-NELLAR, Auteur ; Rolando NARANJO, Auteur ; Mauricio CHINCHILLA, Auteur ; Nicolás GARÓFALO, Auteur ; José VARGAS, Auteur ; Carlos BELTRÁN, Auteur . - p.406-424. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.406-424 Mots-clés : Autism  Autism spectrum disorder  EEG  QEEG Index. décimale : PER Périodiques Résumé : We studied autistics by quantitative EEG spectral and coherence analysis during three experimental conditions: basal, watching a cartoon with audio (V–A), and with muted audio band (VwA). Significant reductions were found for the absolute power spectral density (PSD) in the central region for delta and theta, and in the posterior region for sigma and beta bands, lateralized to the right hemisphere. When comparing VwA versus the V–A in the midline regions, we found significant decrements of absolute PSD for delta, theta and alpha, and increments for the beta and gamma bands. In autistics, VwA versus V–A tended to show lower coherence values in the right hemisphere. An impairment of visual and auditory sensory integration in autistics might explain our results. En ligne : http://dx.doi.org/10.1007/s10803-013-1909-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Guidelines and Best Practices for Electrophysiological Data Collection, Analysis and Reporting in Autism / Sara Jane WEBB in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.425-443 Titre : Guidelines and Best Practices for Electrophysiological Data Collection, Analysis and Reporting in Autism Type de document : Texte imprimé et/ou numérique Auteurs : Sara Jane WEBB, Auteur ; Raphael BERNIER, Auteur ; Heather A. HENDERSON, Auteur ; Mark H. JOHNSON, Auteur ; Emily J. H. JONES, Auteur ; Matthew D. LERNER, Auteur ; James C. MCPARTLAND, Auteur ; Charles A. NELSON, Auteur ; Donald C. ROJAS, Auteur ; Jeanne TOWNSEND, Auteur ; Marissa A. WESTERFIELD, Auteur Article en page(s) : p.425-443 Langues : Anglais (eng) Mots-clés : EEG  Electrophysiology  ERP  Event-related potentials  MEG  Magnetoencephalography  Autism  ASD  Guidelines Index. décimale : PER Périodiques Résumé : The EEG reflects the activation of large populations of neurons that act in synchrony and propagate to the scalp surface. This activity reflects both the brain’s background electrical activity and when the brain is being challenged by a task. Despite strong theoretical and methodological arguments for the use of EEG in understanding the neural correlates of autism, the practice of collecting, processing and evaluating EEG data is complex. Scientists should take into consideration both the nature of development in autism given the life-long, pervasive course of the disorder and the disability of altered or atypical social, communicative, and motor behaviors, all of which require accommodations to traditional EEG environments and paradigms. This paper presents guidelines for the recording, analyzing, and interpreting of EEG data with participants with autism. The goal is to articulate a set of scientific standards as well as methodological considerations that will increase the general field’s understanding of EEG methods, provide support for collaborative projects, and contribute to the evaluation of results and conclusions. En ligne : http://dx.doi.org/10.1007/s10803-013-1916-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Guidelines and Best Practices for Electrophysiological Data Collection, Analysis and Reporting in Autism [Texte imprimé et/ou numérique] / Sara Jane WEBB, Auteur ; Raphael BERNIER, Auteur ; Heather A. HENDERSON, Auteur ; Mark H. JOHNSON, Auteur ; Emily J. H. JONES, Auteur ; Matthew D. LERNER, Auteur ; James C. MCPARTLAND, Auteur ; Charles A. NELSON, Auteur ; Donald C. ROJAS, Auteur ; Jeanne TOWNSEND, Auteur ; Marissa A. WESTERFIELD, Auteur . - p.425-443. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.425-443 Mots-clés : EEG  Electrophysiology  ERP  Event-related potentials  MEG  Magnetoencephalography  Autism  ASD  Guidelines Index. décimale : PER Périodiques Résumé : The EEG reflects the activation of large populations of neurons that act in synchrony and propagate to the scalp surface. This activity reflects both the brain’s background electrical activity and when the brain is being challenged by a task. Despite strong theoretical and methodological arguments for the use of EEG in understanding the neural correlates of autism, the practice of collecting, processing and evaluating EEG data is complex. Scientists should take into consideration both the nature of development in autism given the life-long, pervasive course of the disorder and the disability of altered or atypical social, communicative, and motor behaviors, all of which require accommodations to traditional EEG environments and paradigms. This paper presents guidelines for the recording, analyzing, and interpreting of EEG data with participants with autism. The goal is to articulate a set of scientific standards as well as methodological considerations that will increase the general field’s understanding of EEG methods, provide support for collaborative projects, and contribute to the evaluation of results and conclusions. En ligne : http://dx.doi.org/10.1007/s10803-013-1916-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Joint Analysis of Band-Specific Functional Connectivity and Signal Complexity in Autism / Yasser GHANBARI in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.444-460 Titre : Joint Analysis of Band-Specific Functional Connectivity and Signal Complexity in Autism Type de document : Texte imprimé et/ou numérique Auteurs : Yasser GHANBARI, Auteur ; Luke BLOY, Auteur ; J. CHRISTOPHER EDGAR, Auteur ; Lisa BLASKEY, Auteur ; Ragini VERMA, Auteur ; Timothy P. L. ROBERTS, Auteur Article en page(s) : p.444-460 Langues : Anglais (eng) Mots-clés : Autism  Magnetoencephalography (MEG)  Resting-state  Connectivity  Complexity  Synchronization likelihood (SL)  Multi-scale entropy (MSE) Index. décimale : PER Périodiques Résumé : Examination of resting state brain activity using electrophysiological measures like complexity as well as functional connectivity is of growing interest in the study of autism spectrum disorders (ASD). The present paper jointly examined complexity and connectivity to obtain a more detailed characterization of resting state brain activity in ASD. Multi-scale entropy was computed to quantify the signal complexity, and synchronization likelihood was used to evaluate functional connectivity (FC), with node strength values providing a sensor-level measure of connectivity to facilitate comparisons with complexity. Sensor level analysis of complexity and connectivity was performed at different frequency bands computed from resting state MEG from 26 children with ASD and 22 typically developing controls (TD). Analyses revealed band-specific group differences in each measure that agreed with other functional studies in fMRI and EEG: higher complexity in TD than ASD, in frontal regions in the delta band and occipital-parietal regions in the alpha band, and lower complexity in TD than in ASD in delta (parietal regions), theta (central and temporal regions) and gamma (frontal-central boundary regions); increased short-range connectivity in ASD in the frontal lobe in the delta band and long-range connectivity in the temporal, parietal and occipital lobes in the alpha band. Finally, and perhaps most strikingly, group differences between ASD and TD in complexity and FC appear spatially complementary, such that where FC was elevated in ASD, complexity was reduced (and vice versa). The correlation of regional average complexity and connectivity node strength with symptom severity scores of ASD subjects supported the overall complementarity (with opposing sign) of connectivity and complexity measures, pointing to either diminished connectivity leading to elevated entropy due to poor inhibitory regulation or chaotic signals prohibiting effective measure of connectivity. En ligne : http://dx.doi.org/10.1007/s10803-013-1915-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Joint Analysis of Band-Specific Functional Connectivity and Signal Complexity in Autism [Texte imprimé et/ou numérique] / Yasser GHANBARI, Auteur ; Luke BLOY, Auteur ; J. CHRISTOPHER EDGAR, Auteur ; Lisa BLASKEY, Auteur ; Ragini VERMA, Auteur ; Timothy P. L. ROBERTS, Auteur . - p.444-460. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.444-460 Mots-clés : Autism  Magnetoencephalography (MEG)  Resting-state  Connectivity  Complexity  Synchronization likelihood (SL)  Multi-scale entropy (MSE) Index. décimale : PER Périodiques Résumé : Examination of resting state brain activity using electrophysiological measures like complexity as well as functional connectivity is of growing interest in the study of autism spectrum disorders (ASD). The present paper jointly examined complexity and connectivity to obtain a more detailed characterization of resting state brain activity in ASD. Multi-scale entropy was computed to quantify the signal complexity, and synchronization likelihood was used to evaluate functional connectivity (FC), with node strength values providing a sensor-level measure of connectivity to facilitate comparisons with complexity. Sensor level analysis of complexity and connectivity was performed at different frequency bands computed from resting state MEG from 26 children with ASD and 22 typically developing controls (TD). Analyses revealed band-specific group differences in each measure that agreed with other functional studies in fMRI and EEG: higher complexity in TD than ASD, in frontal regions in the delta band and occipital-parietal regions in the alpha band, and lower complexity in TD than in ASD in delta (parietal regions), theta (central and temporal regions) and gamma (frontal-central boundary regions); increased short-range connectivity in ASD in the frontal lobe in the delta band and long-range connectivity in the temporal, parietal and occipital lobes in the alpha band. Finally, and perhaps most strikingly, group differences between ASD and TD in complexity and FC appear spatially complementary, such that where FC was elevated in ASD, complexity was reduced (and vice versa). The correlation of regional average complexity and connectivity node strength with symptom severity scores of ASD subjects supported the overall complementarity (with opposing sign) of connectivity and complexity measures, pointing to either diminished connectivity leading to elevated entropy due to poor inhibitory regulation or chaotic signals prohibiting effective measure of connectivity. En ligne : http://dx.doi.org/10.1007/s10803-013-1915-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Autonomic Dysregulation During Sensory Stimulation in Children with Autism Spectrum Disorder / Roseann C. SCHAAF in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.461-472 Titre : Autonomic Dysregulation During Sensory Stimulation in Children with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Roseann C. SCHAAF, Auteur ; Teal W. BENEVIDES, Auteur ; Benjamin E. LEIBY, Auteur ; Jocelyn A. SENDECKI, Auteur Article en page(s) : p.461-472 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Sensation  Autonomic nervous system  Parasympathetic nervous system  Sympathetic nervous system Index. décimale : PER Périodiques Résumé : Autonomic nervous system (ANS) activity during sensory stimulation was measured in 59 children with autism spectrum disorder (ASD) ages 6–9 in comparison to 30 typically developing controls. Multivariate comparisons revealed significant differences between groups in the respiratory sinus arrhythmia (parasympathetic measure) vector of means across sensory stimuli (p = 0.02) and in change from domain to domain (p = 0.01). Sympathetic activity, measured by pre-ejection period, did not differ significantly between groups, although it was higher in ASD participants. Findings suggest that participants with ASD demonstrated a different pattern of parasympathetic activity during sensory stimulation. Findings are discussed in relation to the biological mechanisms of sensory processing in autism, insight into the autism phenotype, and the utility of ANS activity as an outcomes marker. En ligne : http://dx.doi.org/10.1007/s10803-013-1924-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Autonomic Dysregulation During Sensory Stimulation in Children with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Roseann C. SCHAAF, Auteur ; Teal W. BENEVIDES, Auteur ; Benjamin E. LEIBY, Auteur ; Jocelyn A. SENDECKI, Auteur . - p.461-472. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.461-472 Mots-clés : Autism spectrum disorders  Sensation  Autonomic nervous system  Parasympathetic nervous system  Sympathetic nervous system Index. décimale : PER Périodiques Résumé : Autonomic nervous system (ANS) activity during sensory stimulation was measured in 59 children with autism spectrum disorder (ASD) ages 6–9 in comparison to 30 typically developing controls. Multivariate comparisons revealed significant differences between groups in the respiratory sinus arrhythmia (parasympathetic measure) vector of means across sensory stimuli (p = 0.02) and in change from domain to domain (p = 0.01). Sympathetic activity, measured by pre-ejection period, did not differ significantly between groups, although it was higher in ASD participants. Findings suggest that participants with ASD demonstrated a different pattern of parasympathetic activity during sensory stimulation. Findings are discussed in relation to the biological mechanisms of sensory processing in autism, insight into the autism phenotype, and the utility of ANS activity as an outcomes marker. En ligne : http://dx.doi.org/10.1007/s10803-013-1924-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Alpha Asymmetry in Infants at Risk for Autism Spectrum Disorders / Laurel GABARD-DURNAM in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.473-480 Titre : Alpha Asymmetry in Infants at Risk for Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Laurel GABARD-DURNAM, Auteur ; Adrienne L. TIERNEY, Auteur ; Vanessa VOGEL-FARLEY, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Charles A. NELSON, Auteur Article en page(s) : p.473-480 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Infant siblings  Electroencephalography  Frontal alpha asymmetry  Endophenotype Index. décimale : PER Périodiques Résumé : An emerging focus of research on autism spectrum disorder (ASD) targets the identification of early-developing ASD endophenotypes using infant siblings of affected children. One potential neural endophenotype is resting frontal electroencephalogram (EEG) alpha asymmetry, a metric of hemispheric organization. Here, we examined the development of frontal EEG alpha asymmetry in ASD high-risk and low-risk infant populations. Our findings demonstrate that low and high-risk infants show different patterns of alpha asymmetry at 6 months of age and opposite growth trajectories in asymmetry over the following 12 months. These results support the candidacy of alpha asymmetry as an early neural ASD endophenotype. En ligne : http://dx.doi.org/10.1007/s10803-013-1926-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Alpha Asymmetry in Infants at Risk for Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Laurel GABARD-DURNAM, Auteur ; Adrienne L. TIERNEY, Auteur ; Vanessa VOGEL-FARLEY, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Charles A. NELSON, Auteur . - p.473-480. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.473-480 Mots-clés : Autism spectrum disorder  Infant siblings  Electroencephalography  Frontal alpha asymmetry  Endophenotype Index. décimale : PER Périodiques Résumé : An emerging focus of research on autism spectrum disorder (ASD) targets the identification of early-developing ASD endophenotypes using infant siblings of affected children. One potential neural endophenotype is resting frontal electroencephalogram (EEG) alpha asymmetry, a metric of hemispheric organization. Here, we examined the development of frontal EEG alpha asymmetry in ASD high-risk and low-risk infant populations. Our findings demonstrate that low and high-risk infants show different patterns of alpha asymmetry at 6 months of age and opposite growth trajectories in asymmetry over the following 12 months. These results support the candidacy of alpha asymmetry as an early neural ASD endophenotype. En ligne : http://dx.doi.org/10.1007/s10803-013-1926-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Cardiac Reactivity and Stimulant Use in Adolescents with Autism Spectrum Disorders with Comorbid ADHD Versus ADHD / Marleen BINK in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.481-494 Titre : Cardiac Reactivity and Stimulant Use in Adolescents with Autism Spectrum Disorders with Comorbid ADHD Versus ADHD Type de document : Texte imprimé et/ou numérique Auteurs : Marleen BINK, Auteur ; A. POPMA, Auteur ; Ilja L. BONGERS, Auteur ; G. J. M. VAN BOXTEL, Auteur ; A. DENISSEN, Auteur ; Ch. VAN NIEUWENHUIZEN, Auteur Article en page(s) : p.481-494 Langues : Anglais (eng) Mots-clés : Cardiac adaptation  HRV  ASD  ADHD  Stimulant medication Index. décimale : PER Périodiques Résumé : A large number of youngsters with autism spectrum disorders (ASD) display comorbid attention deficit/hyperactivity disorder (ADHD) symptoms. However, previous studies are not conclusive whether psychophysiological correlates, like cardiac reactivity, are different for ASD with comorbid ADHD (ASD+) compared to ADHD. Therefore, the current study investigated (dis)similarities in cardiac reactivity and attention task performance. In a clinical sample, adolescents diagnosed with ASD+ (n = 20) versus ADHD (n = 36) and stimulant medication use (56 %) were compared during a baseline with eyes closed and task performance. Results for cardiac reactivity were similar for both diagnostic groups. Stimulant-medicated adolescents showed decreased adaptation of LF/HF ratio and faster reaction times than stimulant-free adolescents. The current study underlines the psychophysiological overlap of ADHD symptoms in adolescents with ASD+ and adolescents with ADHD. En ligne : http://dx.doi.org/10.1007/s10803-013-1929-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Cardiac Reactivity and Stimulant Use in Adolescents with Autism Spectrum Disorders with Comorbid ADHD Versus ADHD [Texte imprimé et/ou numérique] / Marleen BINK, Auteur ; A. POPMA, Auteur ; Ilja L. BONGERS, Auteur ; G. J. M. VAN BOXTEL, Auteur ; A. DENISSEN, Auteur ; Ch. VAN NIEUWENHUIZEN, Auteur . - p.481-494. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.481-494 Mots-clés : Cardiac adaptation  HRV  ASD  ADHD  Stimulant medication Index. décimale : PER Périodiques Résumé : A large number of youngsters with autism spectrum disorders (ASD) display comorbid attention deficit/hyperactivity disorder (ADHD) symptoms. However, previous studies are not conclusive whether psychophysiological correlates, like cardiac reactivity, are different for ASD with comorbid ADHD (ASD+) compared to ADHD. Therefore, the current study investigated (dis)similarities in cardiac reactivity and attention task performance. In a clinical sample, adolescents diagnosed with ASD+ (n = 20) versus ADHD (n = 36) and stimulant medication use (56 %) were compared during a baseline with eyes closed and task performance. Results for cardiac reactivity were similar for both diagnostic groups. Stimulant-medicated adolescents showed decreased adaptation of LF/HF ratio and faster reaction times than stimulant-free adolescents. The current study underlines the psychophysiological overlap of ADHD symptoms in adolescents with ASD+ and adolescents with ADHD. En ligne : http://dx.doi.org/10.1007/s10803-013-1929-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Exploring the Relationship of Autonomic and Endocrine Activity with Social Functioning in Adults with Autism Spectrum Disorders / I. SMEEKENS in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.495-505 Titre : Exploring the Relationship of Autonomic and Endocrine Activity with Social Functioning in Adults with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : I. SMEEKENS, Auteur ; R. DIDDEN, Auteur ; E. W. M. VERHOEVEN, Auteur Article en page(s) : p.495-505 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Autonomic  Endocrine  Social functioning  Adults Index. décimale : PER Périodiques Résumé : Several studies indicate that autonomic and endocrine activity may be related to social functioning in individuals with autism spectrum disorder (ASD), although the number of studies in adults is limited. The present study explored the relationship of autonomic and endocrine activity with social functioning in young adult males with ASD compared to young adult males without ASD. Autonomic and endocrine activity (i.e. heart rate, heart rate variability and salivary cortisol) were measured during rest and social interaction. No differences in heart rate, heart rate variability and cortisol between both groups were found during rest and social interaction. Repeated measures ANOVA’s indicate a main effect of time for heart rate and cortisol, indicating an increase in these measures for both groups. An interaction effect between time and group was found for heart rate, with the ASD group showing a blunted increase in heart rate from rest to social interaction as compared to those without ASD. Future research should focus on replicating the present findings with larger sample sizes which also enables assessing inter-individual variability in autonomic and endocrine activity in relation to social functioning. En ligne : http://dx.doi.org/10.1007/s10803-013-1947-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Exploring the Relationship of Autonomic and Endocrine Activity with Social Functioning in Adults with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / I. SMEEKENS, Auteur ; R. DIDDEN, Auteur ; E. W. M. VERHOEVEN, Auteur . - p.495-505. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.495-505 Mots-clés : Autism spectrum disorder  Autonomic  Endocrine  Social functioning  Adults Index. décimale : PER Périodiques Résumé : Several studies indicate that autonomic and endocrine activity may be related to social functioning in individuals with autism spectrum disorder (ASD), although the number of studies in adults is limited. The present study explored the relationship of autonomic and endocrine activity with social functioning in young adult males with ASD compared to young adult males without ASD. Autonomic and endocrine activity (i.e. heart rate, heart rate variability and salivary cortisol) were measured during rest and social interaction. No differences in heart rate, heart rate variability and cortisol between both groups were found during rest and social interaction. Repeated measures ANOVA’s indicate a main effect of time for heart rate and cortisol, indicating an increase in these measures for both groups. An interaction effect between time and group was found for heart rate, with the ASD group showing a blunted increase in heart rate from rest to social interaction as compared to those without ASD. Future research should focus on replicating the present findings with larger sample sizes which also enables assessing inter-individual variability in autonomic and endocrine activity in relation to social functioning. En ligne : http://dx.doi.org/10.1007/s10803-013-1947-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Attenuated Auditory Event-Related Potentials and Associations with Atypical Sensory Response Patterns in Children with Autism / Franc C L. DONKERS in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.506-523 Titre : Attenuated Auditory Event-Related Potentials and Associations with Atypical Sensory Response Patterns in Children with Autism Type de document : Texte imprimé et/ou numérique Auteurs : Franc C L. DONKERS, Auteur ; Sarah E. SCHIPUL, Auteur ; Grace T. BARANEK, Auteur ; Katherine M. CLEARY, Auteur ; Michael T. WILLOUGHBY, Auteur ; Anna M. EVANS, Auteur ; John C. BULLUCK, Auteur ; Jeanne E. LOVMO, Auteur ; Aysenil BELGER, Auteur Article en page(s) : p.506-523 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Sensory processing  Event-related potentials  P1  N2  P3a Index. décimale : PER Périodiques Résumé : Neurobiological underpinnings of unusual sensory features in individuals with autism are unknown. Event-related potentials elicited by task-irrelevant sounds were used to elucidate neural correlates of auditory processing and associations with three common sensory response patterns (hyperresponsiveness; hyporesponsiveness; sensory seeking). Twenty-eight children with autism and 39 typically developing children (4–12 year-olds) completed an auditory oddball paradigm. Results revealed marginally attenuated P1 and N2 to standard tones and attenuated P3a to novel sounds in autism versus controls. Exploratory analyses suggested that within the autism group, attenuated N2 and P3a amplitudes were associated with greater sensory seeking behaviors for specific ranges of P1 responses. Findings suggest that attenuated early sensory as well as later attention-orienting neural responses to stimuli may underlie selective sensory features via complex mechanisms. En ligne : http://dx.doi.org/10.1007/s10803-013-1948-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Attenuated Auditory Event-Related Potentials and Associations with Atypical Sensory Response Patterns in Children with Autism [Texte imprimé et/ou numérique] / Franc C L. DONKERS, Auteur ; Sarah E. SCHIPUL, Auteur ; Grace T. BARANEK, Auteur ; Katherine M. CLEARY, Auteur ; Michael T. WILLOUGHBY, Auteur ; Anna M. EVANS, Auteur ; John C. BULLUCK, Auteur ; Jeanne E. LOVMO, Auteur ; Aysenil BELGER, Auteur . - p.506-523. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.506-523 Mots-clés : Autism spectrum disorder  Sensory processing  Event-related potentials  P1  N2  P3a Index. décimale : PER Périodiques Résumé : Neurobiological underpinnings of unusual sensory features in individuals with autism are unknown. Event-related potentials elicited by task-irrelevant sounds were used to elucidate neural correlates of auditory processing and associations with three common sensory response patterns (hyperresponsiveness; hyporesponsiveness; sensory seeking). Twenty-eight children with autism and 39 typically developing children (4–12 year-olds) completed an auditory oddball paradigm. Results revealed marginally attenuated P1 and N2 to standard tones and attenuated P3a to novel sounds in autism versus controls. Exploratory analyses suggested that within the autism group, attenuated N2 and P3a amplitudes were associated with greater sensory seeking behaviors for specific ranges of P1 responses. Findings suggest that attenuated early sensory as well as later attention-orienting neural responses to stimuli may underlie selective sensory features via complex mechanisms. En ligne : http://dx.doi.org/10.1007/s10803-013-1948-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Use of Transcranial Magnetic Stimulation in Autism Spectrum Disorders / Lindsay M. OBERMAN in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.524-536 Titre : Use of Transcranial Magnetic Stimulation in Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Lindsay M. OBERMAN, Auteur ; Alexander ROTENBERG, Auteur ; Alvaro PASCUAL-LEONE, Auteur Article en page(s) : p.524-536 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Transcranial magnetic stimulation  TMS  Diagnosis  Therapy Index. décimale : PER Périodiques Résumé : The clinical, social and financial burden of autism spectrum disorder (ASD) is staggering. We urgently need valid and reliable biomarkers for diagnosis and effective treatments targeting the often debilitating symptoms. Transcranial magnetic stimulation (TMS) is beginning to be used by a number of centers worldwide and may represent a novel technique with both diagnostic and therapeutic potential. Here we critically review the current scientific evidence for the use of TMS in ASD. Though preliminary data suggests promise, there is simply not enough evidence yet to conclusively support the clinical widespread use of TMS in ASD, neither diagnostically nor therapeutically. Carefully designed and properly controlled clinical trials are warranted to evaluate the true potential of TMS in ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1960-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Use of Transcranial Magnetic Stimulation in Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Lindsay M. OBERMAN, Auteur ; Alexander ROTENBERG, Auteur ; Alvaro PASCUAL-LEONE, Auteur . - p.524-536. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.524-536 Mots-clés : Autism spectrum disorder  Transcranial magnetic stimulation  TMS  Diagnosis  Therapy Index. décimale : PER Périodiques Résumé : The clinical, social and financial burden of autism spectrum disorder (ASD) is staggering. We urgently need valid and reliable biomarkers for diagnosis and effective treatments targeting the often debilitating symptoms. Transcranial magnetic stimulation (TMS) is beginning to be used by a number of centers worldwide and may represent a novel technique with both diagnostic and therapeutic potential. Here we critically review the current scientific evidence for the use of TMS in ASD. Though preliminary data suggests promise, there is simply not enough evidence yet to conclusively support the clinical widespread use of TMS in ASD, neither diagnostically nor therapeutically. Carefully designed and properly controlled clinical trials are warranted to evaluate the true potential of TMS in ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1960-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Reduced Interhemispheric Connectivity in Childhood Autism Detected by Electroencephalographic Photic Driving Coherence / Vladimir V. LAZAREV in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.537-547 Titre : Reduced Interhemispheric Connectivity in Childhood Autism Detected by Electroencephalographic Photic Driving Coherence Type de document : Texte imprimé et/ou numérique Auteurs : Vladimir V. LAZAREV, Auteur ; Adailton PONTES, Auteur ; Andrey A. MITROFANOV, Auteur ; Leonardo C. DEAZEVEDO, Auteur Article en page(s) : p.537-547 Langues : Anglais (eng) Mots-clés : Autism  Children  Electroencephalogram  EEG photic driving  EEG coherence  Interhemispheric functional connectivity Index. décimale : PER Périodiques Résumé : The EEG coherence among 14 scalp points during intermittent photic stimulation at 11 fixed frequencies of 3–24 Hz was studied in 14 boys with autism, aged 6–14 years, with relatively intact verbal and intellectual functions, and 19 normally developing boys. The number of interhemispheric coherent connections pertaining to the 20 highest connections of each individual was significantly lower in autistic patients than in the control group at all the EEG beta frequencies corresponding to those of stimulation. The coefficient of coherence values between homologous occipital, parietal and central areas at the same frequencies were also lower in the autistic group in both mono- and bipolar montages due to a deficit in reactive photic driving increase. No differences between the groups were observed in the spontaneous EEG. En ligne : http://dx.doi.org/10.1007/s10803-013-1959-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Reduced Interhemispheric Connectivity in Childhood Autism Detected by Electroencephalographic Photic Driving Coherence [Texte imprimé et/ou numérique] / Vladimir V. LAZAREV, Auteur ; Adailton PONTES, Auteur ; Andrey A. MITROFANOV, Auteur ; Leonardo C. DEAZEVEDO, Auteur . - p.537-547. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.537-547 Mots-clés : Autism  Children  Electroencephalogram  EEG photic driving  EEG coherence  Interhemispheric functional connectivity Index. décimale : PER Périodiques Résumé : The EEG coherence among 14 scalp points during intermittent photic stimulation at 11 fixed frequencies of 3–24 Hz was studied in 14 boys with autism, aged 6–14 years, with relatively intact verbal and intellectual functions, and 19 normally developing boys. The number of interhemispheric coherent connections pertaining to the 20 highest connections of each individual was significantly lower in autistic patients than in the control group at all the EEG beta frequencies corresponding to those of stimulation. The coefficient of coherence values between homologous occipital, parietal and central areas at the same frequencies were also lower in the autistic group in both mono- and bipolar montages due to a deficit in reactive photic driving increase. No differences between the groups were observed in the spontaneous EEG. En ligne : http://dx.doi.org/10.1007/s10803-013-1959-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

The Costs and Benefits of Self-monitoring for Higher Functioning Children and Adolescents with Autism / Heather A. HENDERSON in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.548-559 Titre : The Costs and Benefits of Self-monitoring for Higher Functioning Children and Adolescents with Autism Type de document : Texte imprimé et/ou numérique Auteurs : Heather A. HENDERSON, Auteur ; Kim E. ONO, Auteur ; Camilla M. MCMAHON, Auteur ; Caley B. SCHWARTZ, Auteur ; Lauren V. USHER, Auteur ; Peter C. MUNDY, Auteur Article en page(s) : p.548-559 Langues : Anglais (eng) Mots-clés : Response monitoring  ERN  Higher functioning autism  Internalizing Index. décimale : PER Périodiques Résumé : The ability to regulate behaviors and emotions depends in part on the ability to flexibly monitor one’s own progress toward a goal. Atypical patterns of response monitoring have been reported in individuals with autism spectrum disorders (ASD). In the current study we examined the error related negativity (ERN), an electrophysiological index of response monitoring, in relation to behavioral, social cognitive, and emotional presentation in higher functioning children (8–16 years) diagnosed with autism (HFA: N = 38) and an age- and IQ-matched sample of children without autism (COM: N = 36). Both HFA and COM participants displayed larger amplitude responses to error compared to correct response trials and these amplitudes did not differ by diagnostic group. For participants with HFA, larger ERN amplitudes were associated with more parent-reported autistic symptoms and more self-reported internalizing problems. However, across the full sample, larger ERN amplitudes were associated with better performance on theory of mind tasks. The results are discussed in terms of the utility of electrophysiological measures for understanding essential moderating processes that contribute to the spectrum of behavioral expression in the development of ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1968-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] The Costs and Benefits of Self-monitoring for Higher Functioning Children and Adolescents with Autism [Texte imprimé et/ou numérique] / Heather A. HENDERSON, Auteur ; Kim E. ONO, Auteur ; Camilla M. MCMAHON, Auteur ; Caley B. SCHWARTZ, Auteur ; Lauren V. USHER, Auteur ; Peter C. MUNDY, Auteur . - p.548-559. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.548-559 Mots-clés : Response monitoring  ERN  Higher functioning autism  Internalizing Index. décimale : PER Périodiques Résumé : The ability to regulate behaviors and emotions depends in part on the ability to flexibly monitor one’s own progress toward a goal. Atypical patterns of response monitoring have been reported in individuals with autism spectrum disorders (ASD). In the current study we examined the error related negativity (ERN), an electrophysiological index of response monitoring, in relation to behavioral, social cognitive, and emotional presentation in higher functioning children (8–16 years) diagnosed with autism (HFA: N = 38) and an age- and IQ-matched sample of children without autism (COM: N = 36). Both HFA and COM participants displayed larger amplitude responses to error compared to correct response trials and these amplitudes did not differ by diagnostic group. For participants with HFA, larger ERN amplitudes were associated with more parent-reported autistic symptoms and more self-reported internalizing problems. However, across the full sample, larger ERN amplitudes were associated with better performance on theory of mind tasks. The results are discussed in terms of the utility of electrophysiological measures for understanding essential moderating processes that contribute to the spectrum of behavioral expression in the development of ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1968-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

A Review of Cardiac Autonomic Measures: Considerations for Examination of Physiological Response in Children with Autism Spectrum Disorder / Teal W. BENEVIDES in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.560-575 Titre : A Review of Cardiac Autonomic Measures: Considerations for Examination of Physiological Response in Children with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Teal W. BENEVIDES, Auteur ; Shelly J. LANE, Auteur Article en page(s) : p.560-575 Langues : Anglais (eng) Mots-clés : Autonomic nervous system  Autism spectrum disorder  Parasympathetic  Sympathetic  Review Index. décimale : PER Périodiques Résumé : The autonomic nervous system (ANS) is responsible for multiple physiological responses, and dysfunction of this system is often hypothesized as contributing to cognitive, affective, and behavioral responses in children. Research suggests that examination of ANS activity may provide insight into behavioral dysregulation in children with autism spectrum disorders (ASD), however, there is wide variability in samples, methods, and measures reported. The purpose of this review is to describe frequently reported cardiac ANS measures; discuss theoretical models linking ANS measures with neurological structures; and synthesize pediatric literature using ANS measures on typical and ASD samples. Such a synthesis will provide researchers with a foundation for the use of ANS cardiac methods and measures in ASD research. En ligne : http://dx.doi.org/10.1007/s10803-013-1971-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] A Review of Cardiac Autonomic Measures: Considerations for Examination of Physiological Response in Children with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Teal W. BENEVIDES, Auteur ; Shelly J. LANE, Auteur . - p.560-575. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.560-575 Mots-clés : Autonomic nervous system  Autism spectrum disorder  Parasympathetic  Sympathetic  Review Index. décimale : PER Périodiques Résumé : The autonomic nervous system (ANS) is responsible for multiple physiological responses, and dysfunction of this system is often hypothesized as contributing to cognitive, affective, and behavioral responses in children. Research suggests that examination of ANS activity may provide insight into behavioral dysregulation in children with autism spectrum disorders (ASD), however, there is wide variability in samples, methods, and measures reported. The purpose of this review is to describe frequently reported cardiac ANS measures; discuss theoretical models linking ANS measures with neurological structures; and synthesize pediatric literature using ANS measures on typical and ASD samples. Such a synthesis will provide researchers with a foundation for the use of ANS cardiac methods and measures in ASD research. En ligne : http://dx.doi.org/10.1007/s10803-013-1971-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Lower Electrodermal Activity to Acute Stress in Caregivers of People with Autism Spectrum Disorder: An Adaptive Habituation to Stress / Nicolás RUIZ-ROBLEDILLO in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.576-588 Titre : Lower Electrodermal Activity to Acute Stress in Caregivers of People with Autism Spectrum Disorder: An Adaptive Habituation to Stress Type de document : Texte imprimé et/ou numérique Auteurs : Nicolás RUIZ-ROBLEDILLO, Auteur ; Luis MOYA-ALBIOL, Auteur Article en page(s) : p.576-588 Langues : Anglais (eng) Mots-clés : Electrodermal activity  Caregivers  Autism spectrum disorder  Autonomic nervous system  Health Index. décimale : PER Périodiques Résumé : Caring for a relative with autism spectrum disorder (ASD) entails being under chronic stress that could alter body homeostasis. Electrodermal activity (EDA) is an index of the sympathetic activity of the autonomic nervous system related to emotionality and homeostasis. This study compares EDA in response to acute stress in the laboratory between parents of people with (n = 30) and without (n = 34) ASD (caregivers and non-caregivers, respectively). Caregivers showed lower EDA in response to acute stress than non-caregivers. They also presented higher trait anxiety, anger, depression, and somatic symptoms than non-caregivers. Higher EDA was related to a worse mood and more severe somatic symptoms only in caregivers. These results could reflect an adaptive habituation to stress and establish that high EDA in response to acute stress depends on caregivers’ health. En ligne : http://dx.doi.org/10.1007/s10803-013-1996-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Lower Electrodermal Activity to Acute Stress in Caregivers of People with Autism Spectrum Disorder: An Adaptive Habituation to Stress [Texte imprimé et/ou numérique] / Nicolás RUIZ-ROBLEDILLO, Auteur ; Luis MOYA-ALBIOL, Auteur . - p.576-588. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.576-588 Mots-clés : Electrodermal activity  Caregivers  Autism spectrum disorder  Autonomic nervous system  Health Index. décimale : PER Périodiques Résumé : Caring for a relative with autism spectrum disorder (ASD) entails being under chronic stress that could alter body homeostasis. Electrodermal activity (EDA) is an index of the sympathetic activity of the autonomic nervous system related to emotionality and homeostasis. This study compares EDA in response to acute stress in the laboratory between parents of people with (n = 30) and without (n = 34) ASD (caregivers and non-caregivers, respectively). Caregivers showed lower EDA in response to acute stress than non-caregivers. They also presented higher trait anxiety, anger, depression, and somatic symptoms than non-caregivers. Higher EDA was related to a worse mood and more severe somatic symptoms only in caregivers. These results could reflect an adaptive habituation to stress and establish that high EDA in response to acute stress depends on caregivers’ health. En ligne : http://dx.doi.org/10.1007/s10803-013-1996-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Sex Differences in Social Perception in Children with ASD / M. C. COFFMAN in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.589-599 Titre : Sex Differences in Social Perception in Children with ASD Type de document : Texte imprimé et/ou numérique Auteurs : M. C. COFFMAN, Auteur ; L. C. ANDERSON, Auteur ; A. J. NAPLES, Auteur ; J. C. MCPARTLAND, Auteur Article en page(s) : p.589-599 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Sex differences  ERP  N170  Face perception Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is more common in males than females. An underrepresentation of females in the ASD literature has led to limited knowledge of differences in social function across the sexes. Investigations of face perception represent a promising target for understanding variability in social functioning between males and females. The current study analyzed electrophysiological brain recordings during face perception to investigate sex differences in the neural correlates of face perception and their relationship to social function. Event related potentials (ERP) were recorded from children with ASD while viewing faces, inverted faces, and houses. Relative to males, females showed attenuated response at an ERP marker of face perception, the N170. Among females, but not males, atypical face response was associated with symptom severity. Observed sex differences reflect influential differences in social information processing, and impairment in these features correlates with deficits in social information processing in females, but not males, with ASD. These findings hold significance for future treatment protocols, which should account for differences in males and females with ASD in clinical presentation and neural phenotypes. En ligne : http://dx.doi.org/10.1007/s10803-013-2006-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Sex Differences in Social Perception in Children with ASD [Texte imprimé et/ou numérique] / M. C. COFFMAN, Auteur ; L. C. ANDERSON, Auteur ; A. J. NAPLES, Auteur ; J. C. MCPARTLAND, Auteur . - p.589-599. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.589-599 Mots-clés : Autism spectrum disorder  Sex differences  ERP  N170  Face perception Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is more common in males than females. An underrepresentation of females in the ASD literature has led to limited knowledge of differences in social function across the sexes. Investigations of face perception represent a promising target for understanding variability in social functioning between males and females. The current study analyzed electrophysiological brain recordings during face perception to investigate sex differences in the neural correlates of face perception and their relationship to social function. Event related potentials (ERP) were recorded from children with ASD while viewing faces, inverted faces, and houses. Relative to males, females showed attenuated response at an ERP marker of face perception, the N170. Among females, but not males, atypical face response was associated with symptom severity. Observed sex differences reflect influential differences in social information processing, and impairment in these features correlates with deficits in social information processing in females, but not males, with ASD. These findings hold significance for future treatment protocols, which should account for differences in males and females with ASD in clinical presentation and neural phenotypes. En ligne : http://dx.doi.org/10.1007/s10803-013-2006-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Tracking the Sensory Environment: An ERP Study of Probability and Context Updating in ASD / Marissa A. WESTERFIELD in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.600-611 Titre : Tracking the Sensory Environment: An ERP Study of Probability and Context Updating in ASD Type de document : Texte imprimé et/ou numérique Auteurs : Marissa A. WESTERFIELD, Auteur ; Marla ZINNI, Auteur ; Khang VO, Auteur ; Jeanne TOWNSEND, Auteur Article en page(s) : p.600-611 Langues : Anglais (eng) Mots-clés : Autism  ASD  ERP  Attention  P3 Index. décimale : PER Périodiques Résumé : We recorded visual event-related brain potentials from 32 adult male participants (16 high-functioning participants diagnosed with autism spectrum disorder (ASD) and 16 control participants, ranging in age from 18 to 53 years) during a three-stimulus oddball paradigm. Target and non-target stimulus probability was varied across three probability conditions, whereas the probability of a third non-target stimulus was held constant in all conditions. P3 amplitude to target stimuli was more sensitive to probability in ASD than in typically developing participants, whereas P3 amplitude to non-target stimuli was less responsive to probability in ASD participants. This suggests that neural responses to changes in event probability are attention-dependant in high-functioning ASD. The implications of these findings for higher-level behaviors such as prediction and planning are discussed. En ligne : http://dx.doi.org/10.1007/s10803-014-2045-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Tracking the Sensory Environment: An ERP Study of Probability and Context Updating in ASD [Texte imprimé et/ou numérique] / Marissa A. WESTERFIELD, Auteur ; Marla ZINNI, Auteur ; Khang VO, Auteur ; Jeanne TOWNSEND, Auteur . - p.600-611. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.600-611 Mots-clés : Autism  ASD  ERP  Attention  P3 Index. décimale : PER Périodiques Résumé : We recorded visual event-related brain potentials from 32 adult male participants (16 high-functioning participants diagnosed with autism spectrum disorder (ASD) and 16 control participants, ranging in age from 18 to 53 years) during a three-stimulus oddball paradigm. Target and non-target stimulus probability was varied across three probability conditions, whereas the probability of a third non-target stimulus was held constant in all conditions. P3 amplitude to target stimuli was more sensitive to probability in ASD than in typically developing participants, whereas P3 amplitude to non-target stimuli was less responsive to probability in ASD participants. This suggests that neural responses to changes in event probability are attention-dependant in high-functioning ASD. The implications of these findings for higher-level behaviors such as prediction and planning are discussed. En ligne : http://dx.doi.org/10.1007/s10803-014-2045-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258