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Altered Neural Connectivity in Females, But Not Males with Autism: Preliminary Evidence for the Female Protective Effect from a Quality-Controlled Diffusion Tensor Imaging Study / J. LEI in Autism Research, 12-10 (October 2019)
[article]
Titre : Altered Neural Connectivity in Females, But Not Males with Autism: Preliminary Evidence for the Female Protective Effect from a Quality-Controlled Diffusion Tensor Imaging Study Type de document : Texte imprimé et/ou numérique Auteurs : J. LEI, Auteur ; E. LECARIE, Auteur ; J. JURAYJ, Auteur ; S. BOLAND, Auteur ; D. G. SUKHODOLSKY, Auteur ; Pamela VENTOLA, Auteur ; Kevin A. PELPHREY, Auteur ; R. J. JOU, Auteur Article en page(s) : p.1472-1483 Langues : Anglais (eng) Mots-clés : anisotropy autism spectrum disorder diffusion tensor imaging female motion sex characteristics Index. décimale : PER Périodiques Résumé : Previous studies using diffusion tensor imaging (DTI) to investigate white matter (WM) structural connectivity have suggested widespread, although inconsistent WM alterations in autism spectrum disorder (ASD), such as greater reductions in fractional anisotropy (FA). However, findings may lack generalizability because: (a) most have focused solely on the ASD male brain phenotype, and not sex-differences in WM integrity; (b) many lack stringent and transparent data quality control such as controlling for head motion in analysis. This study addressed both issues by using Tract-Based Spatial Statistics (TBSS) to separately compare WM differences in 81 ASD (56 male, 25 female; 4-21 years old) and 39 typically developing (TD; 23 males, 16 females; 5-18 years old) children and young people, carefully group-matched on sex, age, cognitive abilities, and head motion. ASD males and females were also matched on autism symptom severity. Two independent-raters completed a multistep scan quality assurance to remove images that were significantly distorted by motion artifacts before analysis. ASD females exhibited significant widespread reductions in FA compared to TD females, suggesting altered WM integrity. In contrast, no significant localized or widespread WM differences were found between ASD and TD males. This study highlights the importance of data quality control in DTI, and outlines important sex-differences in WM alterations in ASD females. Future studies can explore the extent to which neural structural differences might underlie sex-differences in ASD behavioral phenotype, and guide clinical interventions to be tailored toward the unique needs of ASD females and males. Autism Res 2019, 12: 1472-1483. (c) 2019 The Authors. Autism Research published by International Society for Autism Research published by Wiley Periodicals, Inc. LAY SUMMARY: Previous Diffusion Tensor Imaging (DTI) studies have found atypical brain structural connectivity in males with autism, although findings are inconclusive in females with autism. To investigate potential sex-differences, we studied males and females with and without autism who showed a similar level of head movement during their brain scan. We found that females with autism had widespread atypical neural connectivity than females without autism, although not in males, highlighting sex-differences. En ligne : http://dx.doi.org/10.1002/aur.2180 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=408
in Autism Research > 12-10 (October 2019) . - p.1472-1483[article] Altered Neural Connectivity in Females, But Not Males with Autism: Preliminary Evidence for the Female Protective Effect from a Quality-Controlled Diffusion Tensor Imaging Study [Texte imprimé et/ou numérique] / J. LEI, Auteur ; E. LECARIE, Auteur ; J. JURAYJ, Auteur ; S. BOLAND, Auteur ; D. G. SUKHODOLSKY, Auteur ; Pamela VENTOLA, Auteur ; Kevin A. PELPHREY, Auteur ; R. J. JOU, Auteur . - p.1472-1483.
Langues : Anglais (eng)
in Autism Research > 12-10 (October 2019) . - p.1472-1483
Mots-clés : anisotropy autism spectrum disorder diffusion tensor imaging female motion sex characteristics Index. décimale : PER Périodiques Résumé : Previous studies using diffusion tensor imaging (DTI) to investigate white matter (WM) structural connectivity have suggested widespread, although inconsistent WM alterations in autism spectrum disorder (ASD), such as greater reductions in fractional anisotropy (FA). However, findings may lack generalizability because: (a) most have focused solely on the ASD male brain phenotype, and not sex-differences in WM integrity; (b) many lack stringent and transparent data quality control such as controlling for head motion in analysis. This study addressed both issues by using Tract-Based Spatial Statistics (TBSS) to separately compare WM differences in 81 ASD (56 male, 25 female; 4-21 years old) and 39 typically developing (TD; 23 males, 16 females; 5-18 years old) children and young people, carefully group-matched on sex, age, cognitive abilities, and head motion. ASD males and females were also matched on autism symptom severity. Two independent-raters completed a multistep scan quality assurance to remove images that were significantly distorted by motion artifacts before analysis. ASD females exhibited significant widespread reductions in FA compared to TD females, suggesting altered WM integrity. In contrast, no significant localized or widespread WM differences were found between ASD and TD males. This study highlights the importance of data quality control in DTI, and outlines important sex-differences in WM alterations in ASD females. Future studies can explore the extent to which neural structural differences might underlie sex-differences in ASD behavioral phenotype, and guide clinical interventions to be tailored toward the unique needs of ASD females and males. Autism Res 2019, 12: 1472-1483. (c) 2019 The Authors. Autism Research published by International Society for Autism Research published by Wiley Periodicals, Inc. LAY SUMMARY: Previous Diffusion Tensor Imaging (DTI) studies have found atypical brain structural connectivity in males with autism, although findings are inconclusive in females with autism. To investigate potential sex-differences, we studied males and females with and without autism who showed a similar level of head movement during their brain scan. We found that females with autism had widespread atypical neural connectivity than females without autism, although not in males, highlighting sex-differences. En ligne : http://dx.doi.org/10.1002/aur.2180 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=408 Altered neural response to rejection-related words in children exposed to maltreatment / Vanessa B. PUETZ in Journal of Child Psychology and Psychiatry, 57-10 (October 2016)
[article]
Titre : Altered neural response to rejection-related words in children exposed to maltreatment Type de document : Texte imprimé et/ou numérique Auteurs : Vanessa B. PUETZ, Auteur ; Essi VIDING, Auteur ; Amy L. PALMER, Auteur ; Philip A. KELLY, Auteur ; Rachael LICKLEY, Auteur ; Iakovina KOUTOUFA, Auteur ; Catherine L. SEBASTIAN, Auteur ; Eamon J. MCCRORY, Auteur Article en page(s) : p.1165-1173 Langues : Anglais (eng) Mots-clés : Child abuse emotion regulation fMRI posttraumatic stress disorder adolescence Index. décimale : PER Périodiques Résumé : Background Children exposed to maltreatment show neural sensitivity to facial cues signalling threat. However, little is known about how maltreatment influences the processing of social threat cues more broadly, and whether atypical processing of social threat cues relates to psychiatric risk. Methods Forty-one 10- to 14-year-old children underwent a social rejection-themed emotional Stroop task during functional magnetic resonance imaging: 21 children with a documented history of maltreatment (11 F) and 19 comparison children with no maltreatment history (11 F). Groups were matched on age, pubertal status, gender, IQ, socioeconomic status, ethnicity and reading ability. Classic colour Stroop stimuli were also administered in the same paradigm to investigate potential differences in general cognitive control. Results Compared with their peers, children who had experienced maltreatment showed reduced activation in the Rejection versus Neutral condition, across circuitry previously implicated in abuse-related posttraumatic stress disorder (PTSD), including the left anterior insula, extending into left ventrolateral prefrontal cortex/orbitofrontal cortex; left amygdala; left inferior parietal cortex (STS); and bilateral visual association cortex, encompassing the cuneus and lingual gyrus. No group differences in neural or behavioural responses were found for the classic colour Stroop conditions. Significant negative associations between activity in bilateral cuneus and STS during the rejection-themed Stroop and higher self-reported PTSD symptomatology, including dissociation, were observed in children exposed to maltreatment. Conclusion Our findings indicate a pattern of altered neural response to social rejection cues in maltreated children. Compared to their peers, these children displayed relative hypoactivation to rejection cues in regions previously associated with PTSD, potentially reflecting an avoidant coping response. It is suggested that such atypical processing of social threat may index latent vulnerability to future psychopathology in general and PTSD in particular. En ligne : http://dx.doi.org/10.1111/jcpp.12595 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=295
in Journal of Child Psychology and Psychiatry > 57-10 (October 2016) . - p.1165-1173[article] Altered neural response to rejection-related words in children exposed to maltreatment [Texte imprimé et/ou numérique] / Vanessa B. PUETZ, Auteur ; Essi VIDING, Auteur ; Amy L. PALMER, Auteur ; Philip A. KELLY, Auteur ; Rachael LICKLEY, Auteur ; Iakovina KOUTOUFA, Auteur ; Catherine L. SEBASTIAN, Auteur ; Eamon J. MCCRORY, Auteur . - p.1165-1173.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 57-10 (October 2016) . - p.1165-1173
Mots-clés : Child abuse emotion regulation fMRI posttraumatic stress disorder adolescence Index. décimale : PER Périodiques Résumé : Background Children exposed to maltreatment show neural sensitivity to facial cues signalling threat. However, little is known about how maltreatment influences the processing of social threat cues more broadly, and whether atypical processing of social threat cues relates to psychiatric risk. Methods Forty-one 10- to 14-year-old children underwent a social rejection-themed emotional Stroop task during functional magnetic resonance imaging: 21 children with a documented history of maltreatment (11 F) and 19 comparison children with no maltreatment history (11 F). Groups were matched on age, pubertal status, gender, IQ, socioeconomic status, ethnicity and reading ability. Classic colour Stroop stimuli were also administered in the same paradigm to investigate potential differences in general cognitive control. Results Compared with their peers, children who had experienced maltreatment showed reduced activation in the Rejection versus Neutral condition, across circuitry previously implicated in abuse-related posttraumatic stress disorder (PTSD), including the left anterior insula, extending into left ventrolateral prefrontal cortex/orbitofrontal cortex; left amygdala; left inferior parietal cortex (STS); and bilateral visual association cortex, encompassing the cuneus and lingual gyrus. No group differences in neural or behavioural responses were found for the classic colour Stroop conditions. Significant negative associations between activity in bilateral cuneus and STS during the rejection-themed Stroop and higher self-reported PTSD symptomatology, including dissociation, were observed in children exposed to maltreatment. Conclusion Our findings indicate a pattern of altered neural response to social rejection cues in maltreated children. Compared to their peers, these children displayed relative hypoactivation to rejection cues in regions previously associated with PTSD, potentially reflecting an avoidant coping response. It is suggested that such atypical processing of social threat may index latent vulnerability to future psychopathology in general and PTSD in particular. En ligne : http://dx.doi.org/10.1111/jcpp.12595 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=295 Altered patterns of brain dynamics linked with body mass index in youth with autism / Lauren KUPIS in Autism Research, 14-5 (May 2021)
[article]
Titre : Altered patterns of brain dynamics linked with body mass index in youth with autism Type de document : Texte imprimé et/ou numérique Auteurs : Lauren KUPIS, Auteur ; Zachary T. GOODMAN, Auteur ; Leigha KIRCHER, Auteur ; Celia ROMERO, Auteur ; Bryce DIRKS, Auteur ; Catie CHANG, Auteur ; Jason S. NOMI, Auteur ; Lucina Q. UDDIN, Auteur Article en page(s) : p.873-886 Langues : Anglais (eng) Mots-clés : autism cognitive flexibility dynamics obesity resting-state functional MRI Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder (ASD) have higher rates of overweight and obesity (OWOB) compared with typically developing (TD) children. Brain functional connectivity differences have been shown in both ASD and OWOB. However, only one study to date has examined ASD and OWOB concurrently, so little is known regarding the neural mechanisms associated with the higher prevalence of OWOB and its behavioral impacts in ASD. We investigated co-activation patterns (CAPs) of brain regions identified by independent component analysis in 129 children and adolescents between 6 and 18?years of age (n =?68 ASD). We examined the interaction between body mass index (BMI) and diagnosis in predicting dynamic brain metrics (dwell time, DT; frequency of occurrence, and transitions between states) as well as dimensional brain-behavior relationships. The relationship between BMI and brain dynamics was moderated by diagnosis (ASD, TD), particularly among the frequency of CAP 4, characterized by co-activation of lateral frontoparietal, temporal, and frontal networks. This pattern was negatively associated with parent-reported inhibition skills. Children with ASD had shorter CAP 1, characterized by co-activation of the subcortical, temporal, sensorimotor, and frontal networks, and CAP 4 DTs compared with TD children. CAP 1 DT was negatively associated with cognitive flexibility, inhibition, social functioning, and BMI. Cognitive flexibility moderated the relationship between BMI and brain dynamics in the visual network. Our findings provide novel evidence of neural mechanisms associated with OWOB in children with ASD. Further, poorer cognitive flexibility may result in increased vulnerability for children with ASD and co-occurring OWOB. LAY SUMMARY: Obesity is a societal epidemic and is common in autism, however, little is known about the neural mechanisms associated with the higher rates of obesity in autism. Here, we find unique patterns of brain dynamics associated with obesity in autism that were not observed in typically developing children. Further, the relationship between body mass index and brain dynamics depended on cognitive flexibility. These findings suggest that individuals with autism may be more vulnerable to the effects of obesity on brain function. Autism Res 2021, 14: 873-886. © 2021 International Society for Autism Research, Wiley Periodicals LLC. En ligne : http://dx.doi.org/10.1002/aur.2488 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=444
in Autism Research > 14-5 (May 2021) . - p.873-886[article] Altered patterns of brain dynamics linked with body mass index in youth with autism [Texte imprimé et/ou numérique] / Lauren KUPIS, Auteur ; Zachary T. GOODMAN, Auteur ; Leigha KIRCHER, Auteur ; Celia ROMERO, Auteur ; Bryce DIRKS, Auteur ; Catie CHANG, Auteur ; Jason S. NOMI, Auteur ; Lucina Q. UDDIN, Auteur . - p.873-886.
Langues : Anglais (eng)
in Autism Research > 14-5 (May 2021) . - p.873-886
Mots-clés : autism cognitive flexibility dynamics obesity resting-state functional MRI Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder (ASD) have higher rates of overweight and obesity (OWOB) compared with typically developing (TD) children. Brain functional connectivity differences have been shown in both ASD and OWOB. However, only one study to date has examined ASD and OWOB concurrently, so little is known regarding the neural mechanisms associated with the higher prevalence of OWOB and its behavioral impacts in ASD. We investigated co-activation patterns (CAPs) of brain regions identified by independent component analysis in 129 children and adolescents between 6 and 18?years of age (n =?68 ASD). We examined the interaction between body mass index (BMI) and diagnosis in predicting dynamic brain metrics (dwell time, DT; frequency of occurrence, and transitions between states) as well as dimensional brain-behavior relationships. The relationship between BMI and brain dynamics was moderated by diagnosis (ASD, TD), particularly among the frequency of CAP 4, characterized by co-activation of lateral frontoparietal, temporal, and frontal networks. This pattern was negatively associated with parent-reported inhibition skills. Children with ASD had shorter CAP 1, characterized by co-activation of the subcortical, temporal, sensorimotor, and frontal networks, and CAP 4 DTs compared with TD children. CAP 1 DT was negatively associated with cognitive flexibility, inhibition, social functioning, and BMI. Cognitive flexibility moderated the relationship between BMI and brain dynamics in the visual network. Our findings provide novel evidence of neural mechanisms associated with OWOB in children with ASD. Further, poorer cognitive flexibility may result in increased vulnerability for children with ASD and co-occurring OWOB. LAY SUMMARY: Obesity is a societal epidemic and is common in autism, however, little is known about the neural mechanisms associated with the higher rates of obesity in autism. Here, we find unique patterns of brain dynamics associated with obesity in autism that were not observed in typically developing children. Further, the relationship between body mass index and brain dynamics depended on cognitive flexibility. These findings suggest that individuals with autism may be more vulnerable to the effects of obesity on brain function. Autism Res 2021, 14: 873-886. © 2021 International Society for Autism Research, Wiley Periodicals LLC. En ligne : http://dx.doi.org/10.1002/aur.2488 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=444 Altered perception-action binding modulates inhibitory control in Gilles de la Tourette syndrome / V. PETRUO in Journal of Child Psychology and Psychiatry, 60-9 (September 2019)
[article]
Titre : Altered perception-action binding modulates inhibitory control in Gilles de la Tourette syndrome Type de document : Texte imprimé et/ou numérique Auteurs : V. PETRUO, Auteur ; B. BODMER, Auteur ; V. C. BRANDT, Auteur ; L. BAUMUNG, Auteur ; V. ROESSNER, Auteur ; A. MUNCHAU, Auteur ; Christian BESTE, Auteur Article en page(s) : p.953-962 Langues : Anglais (eng) Mots-clés : Tourette syndrome cognitive control event related potential neurophysiology response inhibition, inferior parietal cortex, theory of event coding Index. décimale : PER Périodiques Résumé : BACKGROUND: Gilles de la Tourette Syndrome (GTS) is a multifaceted neuropsychiatric developmental disorder with onset in childhood or adolescence and frequent remissions in early adulthood. A rather new emerging concept of this syndrome suggests that it is a disorder of purposeful actions, in which sensory processes and their relation to motor responses (actions) play a particularly important role. Thus, this syndrome might be conceived as a condition of altered 'perception-action binding'. In the current study, we test this novel concept in the context of inhibitory control. METHODS: We examined N = 35 adolescent GTS patients and N = 39 healthy controls in a Go/Nogo-task manipulating the complexity of sensory information triggering identical actions; i.e. to inhibit a motor response. This was combined with event-related potential recordings, EEG data decomposition and source localization. RESULTS: GTS patients showed worse performance compared to controls and larger performance differences when inhibitory control had to be exerted using unimodal visual compared to bimodal auditory-visual stimuli. This suggests increased binding between bimodal stimuli and responses leading to increased costs of switching between responses instructed by bimodal and those instructed by unimodal stimuli. The neurophysiological data showed that this was related to mechanisms mediating between stimulus evaluation and response selection; i.e. perception-action binding processes in the right inferior parietal cortex (BA40). CONCLUSIONS: Stimulus-action inhibition binding is stronger in GTS patients than healthy controls and affects inhibitory control corroborating the concept suggesting that GTS might be a condition of altered perception-action integration (binding); i.e. a disorder of purposeful actions. En ligne : http://dx.doi.org/10.1111/jcpp.12938 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=405
in Journal of Child Psychology and Psychiatry > 60-9 (September 2019) . - p.953-962[article] Altered perception-action binding modulates inhibitory control in Gilles de la Tourette syndrome [Texte imprimé et/ou numérique] / V. PETRUO, Auteur ; B. BODMER, Auteur ; V. C. BRANDT, Auteur ; L. BAUMUNG, Auteur ; V. ROESSNER, Auteur ; A. MUNCHAU, Auteur ; Christian BESTE, Auteur . - p.953-962.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 60-9 (September 2019) . - p.953-962
Mots-clés : Tourette syndrome cognitive control event related potential neurophysiology response inhibition, inferior parietal cortex, theory of event coding Index. décimale : PER Périodiques Résumé : BACKGROUND: Gilles de la Tourette Syndrome (GTS) is a multifaceted neuropsychiatric developmental disorder with onset in childhood or adolescence and frequent remissions in early adulthood. A rather new emerging concept of this syndrome suggests that it is a disorder of purposeful actions, in which sensory processes and their relation to motor responses (actions) play a particularly important role. Thus, this syndrome might be conceived as a condition of altered 'perception-action binding'. In the current study, we test this novel concept in the context of inhibitory control. METHODS: We examined N = 35 adolescent GTS patients and N = 39 healthy controls in a Go/Nogo-task manipulating the complexity of sensory information triggering identical actions; i.e. to inhibit a motor response. This was combined with event-related potential recordings, EEG data decomposition and source localization. RESULTS: GTS patients showed worse performance compared to controls and larger performance differences when inhibitory control had to be exerted using unimodal visual compared to bimodal auditory-visual stimuli. This suggests increased binding between bimodal stimuli and responses leading to increased costs of switching between responses instructed by bimodal and those instructed by unimodal stimuli. The neurophysiological data showed that this was related to mechanisms mediating between stimulus evaluation and response selection; i.e. perception-action binding processes in the right inferior parietal cortex (BA40). CONCLUSIONS: Stimulus-action inhibition binding is stronger in GTS patients than healthy controls and affects inhibitory control corroborating the concept suggesting that GTS might be a condition of altered perception-action integration (binding); i.e. a disorder of purposeful actions. En ligne : http://dx.doi.org/10.1111/jcpp.12938 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=405 Altered Peripheral and Central Inflammatory Responses in a Mouse Model of Autism / Luciana LUCCHINA in Autism Research, 7-2 (April 2014)
[article]
Titre : Altered Peripheral and Central Inflammatory Responses in a Mouse Model of Autism Type de document : Texte imprimé et/ou numérique Auteurs : Luciana LUCCHINA, Auteur ; Amaicha Mara DEPINO, Auteur Article en page(s) : p.273-289 Mots-clés : valproic acid cytokines microglia astroglia hypothalamus–pituitary–adrenal axis behavior Index. décimale : PER Périodiques Résumé : Increasing clinical and experimental evidence links immune and inflammatory alterations with the pathogenesis of autism spectrum disorders (ASD). Autistic individuals show signs of neuroinflammation, altered inflammatory responses, and immune abnormalities throughout life. Mice injected subcutaneously with 600?mg/kg valproic acid (VPA600) at gestational day 12.5 show reduced social interaction in adulthood (at 8 weeks of age), and they have been proposed as a mouse model of autism. Here, we show that these adult animals present signs of chronic glial activation in the hippocampus and the cerebellum. Moreover, when they are challenged with a peripheral inflammatory stimulus (intraperitoneal lipopolysaccharides, LPS), VPA600 animals show an exacerbated inflammatory response. Two hours after LPS injection, VPA600 animals secrete more corticosterone to the blood than control mice, and show an increase in the levels of expression of proinflammatory cytokines in the spleen. After LPS challenge, VPA600 mice also show signs of increased neuroinflammation compared with control mice: they have more microglial cells in the hippocampus, and they show higher levels of proinflammatory cytokines in the cerebellum. Our results provide evidence of basal neuroinflammation and an altered inflammatory response in the VPA model of autism. We propose that this model can be used to evaluate the contribution of inflammatory reactivity to autism-related behaviors. These studies will contribute to elucidate the role of the inflammatory alterations observed in ASD individuals. En ligne : http://dx.doi.org/10.1002/aur.1338 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=230
in Autism Research > 7-2 (April 2014) . - p.273-289[article] Altered Peripheral and Central Inflammatory Responses in a Mouse Model of Autism [Texte imprimé et/ou numérique] / Luciana LUCCHINA, Auteur ; Amaicha Mara DEPINO, Auteur . - p.273-289.
in Autism Research > 7-2 (April 2014) . - p.273-289
Mots-clés : valproic acid cytokines microglia astroglia hypothalamus–pituitary–adrenal axis behavior Index. décimale : PER Périodiques Résumé : Increasing clinical and experimental evidence links immune and inflammatory alterations with the pathogenesis of autism spectrum disorders (ASD). Autistic individuals show signs of neuroinflammation, altered inflammatory responses, and immune abnormalities throughout life. Mice injected subcutaneously with 600?mg/kg valproic acid (VPA600) at gestational day 12.5 show reduced social interaction in adulthood (at 8 weeks of age), and they have been proposed as a mouse model of autism. Here, we show that these adult animals present signs of chronic glial activation in the hippocampus and the cerebellum. Moreover, when they are challenged with a peripheral inflammatory stimulus (intraperitoneal lipopolysaccharides, LPS), VPA600 animals show an exacerbated inflammatory response. Two hours after LPS injection, VPA600 animals secrete more corticosterone to the blood than control mice, and show an increase in the levels of expression of proinflammatory cytokines in the spleen. After LPS challenge, VPA600 mice also show signs of increased neuroinflammation compared with control mice: they have more microglial cells in the hippocampus, and they show higher levels of proinflammatory cytokines in the cerebellum. Our results provide evidence of basal neuroinflammation and an altered inflammatory response in the VPA model of autism. We propose that this model can be used to evaluate the contribution of inflammatory reactivity to autism-related behaviors. These studies will contribute to elucidate the role of the inflammatory alterations observed in ASD individuals. En ligne : http://dx.doi.org/10.1002/aur.1338 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=230 Altered posterior cingulate cortical cyctoarchitecture, but normal density of neurons and interneurons in the posterior cingulate cortex and fusiform gyrus in autism / Adrian L. OBLAK in Autism Research, 4-3 (June 2011)
PermalinkAltered pre-ejection period response to social evaluative threat in adolescents with autism spectrum disorder / E. Kale EDMISTON in Research in Autism Spectrum Disorders, 36 (April 2017)
PermalinkAltered Pre-reflective Sense of Agency in Autism Spectrum Disorders as Revealed by Reduced Intentional Binding / Marco SPERDUTI in Journal of Autism and Developmental Disorders, 44-2 (February 2014)
PermalinkAltered ratio of carbamazepine-10,11-epoxide/carbamazepine in plasma of children: evidence of anticonvulsant drug / Johan F. SCHOEMAN in Developmental Medicine & Child Neurology, 26-6 (December 1994)
PermalinkAltered reward system reactivity for personalized circumscribed interests in autism / G. KOHLS in Molecular Autism, 9 (2018)
PermalinkAltered right frontal cortical connectivity during facial emotion recognition in children with autism spectrum disorders / Michael K. YEUNG in Research in Autism Spectrum Disorders, 8-11 (November 2014)
PermalinkAltered sense of gaze leading in autism / Ouriel GRYNSZPAN in Research in Autism Spectrum Disorders, 67 (November 2019)
PermalinkAltered sensitivity to social gaze in the FMR1 premutation and pragmatic language competence / J. KLUSEK in Journal of Neurodevelopmental Disorders, 9-1 (December 2017)
PermalinkAltered social behavior and ultrasonic communication in the dystrophin-deficient mdx mouse model of Duchenne muscular dystrophy / Rubén MIRANDA in Molecular Autism, (October 2015)
PermalinkAltered Striatal Synaptic Function and Abnormal Behaviour in Shank3 Exon4-9 Deletion Mouse Model of Autism / Thomas C. JARAMILLO in Autism Research, 9-3 (March 2016)
PermalinkAltered Structure–Function Relations of Semantic Processing in Youths with High-Functioning Autism: A Combined Diffusion and Functional MRI Study / Yu-Chun LO in Autism Research, 6-6 (December 2013)
PermalinkAltered synaptic ultrastructure in the prefrontal cortex of Shank3-deficient rats / Sarah JACOT-DESCOMBES in Molecular Autism, 11 (2020)
PermalinkAltered tactile processing in children with autism spectrum disorder / Teresa TAVASSOLI in Autism Research, 9-6 (June 2016)
PermalinkAltered task?related modulation of long?range connectivity in children with autism / Ajay S. PILLAI in Autism Research, 11-2 (February 2018)
PermalinkAltered theta-beta ratio in infancy associates with family history of ADHD and later ADHD-relevant temperamental traits / Jannath BEGUM-ALI in Journal of Child Psychology and Psychiatry, 63-9 (September 2022)
PermalinkAltered ventral striatal–medial prefrontal cortex resting-state connectivity mediates adolescent social problems after early institutional care / Dominic S. FARERI in Development and Psychopathology, 29-5 (December 2017)
PermalinkDe l’alternance à la reliance pour favoriser l’émergence d’un devenir sujet / Elisabeth CASTRO in Thérapie psychomotrice et recherches, 174 (2013)
PermalinkL’alternance : un (vrai) pas vers l’emploi / Mina DAVID in Déclic, 161 (Septembre-Octobre 2014)
PermalinkAlternate Assessment Formats for Progress Monitoring Students With Intellectual Disabilities and Below Average IQ: An Exploratory Study / Francesca G. JONES in Focus on Autism and Other Developmental Disabilities, 34-1 (March 2019)
PermalinkAlternating Stepping Patterns: Hidden Abilities of 11-Month-Old Infants with Down Syndrome / Beverly D. ULRICH in Developmental Medicine & Child Neurology, 34-3 (March 1992)
PermalinkAlternative hypotheses regarding the association between early engagement in gambling and gambling-like activities and later problem gambling - a commentary on Richard and King (2023) / Soo Hyun RHEE in Journal of Child Psychology and Psychiatry, 64-4 (April 2023)
PermalinkAlternative Methods / Martin C. O. BAX in Developmental Medicine & Child Neurology, 34-6 (June 1992)
PermalinkAlternative or unorthodox therapies / G. P. HOSKING in Developmental Medicine & Child Neurology, 29-3 (June 1987)
PermalinkAlternative treatments for autism: Prevalence and predictors / Kim M. JONKMAN in Research in Autism Spectrum Disorders, 98 (October 2022)
PermalinkLes alternatives aux traitements psychotropes. Nouvelles approches dans l'accompagnement des comportements difficiles chez l'adulte avec autisme / Elisabeth DELOUVRIER in Sésame, 196 (Décembre 2015)
Permalink“Always a glass ceiling.” Gender or autism; the barrier to occupational inclusion / Susan M. HAYWARD in Research in Autism Spectrum Disorders, 56 (December 2018)
PermalinkAmazing Awareness Bands: how wristbands help convey emotion / Joan RATCLIFF in Good Autism Practice - GAP, 9-2 (October 2008)
PermalinkAmbiance médiévale en Picardie in Déclic, 135 (Mai-Juin 2010)
PermalinkAmbiguity detection in adolescents with Asperger syndrome: Is central coherence or theory of mind impaired? / Sandrine LE SOURN-BISSAOUI in Research in Autism Spectrum Disorders, 5-1 (January-March 2011)
PermalinkL’ambition participative ou l’invisibilisation sociale / Serge EBERSOLD in Nouvelle Revue de l'AIS (La), 34 (Juin 2006)
PermalinkAMBRA1, Autophagy, and the Extreme Male Brain Theory of Autism / Bernard CRESPI in Autism Research and Treatment, 2019 (2019)
PermalinkAmbulation of children with myelomeningocele: parapodium versus parapodium with Orlau swivel modification / Loretta K. LOUGH in Developmental Medicine & Child Neurology, 28-4 (August 1986)
PermalinkAmbulatory Care Sensitive Admissions in Individuals With Autism Spectrum Disorder, Intellectual Disability, and Population Controls / B. N. HAND in Autism Research, 12-2 (February 2019)
PermalinkAmbulatory Outcome of Children with Myelomeningocele: Effect of Lower-Extremity Muscle Strength / Craig M. MCDONALD in Developmental Medicine & Child Neurology, 33-6 (June 1991)
PermalinkL’âme forme du corps et est-ce que l’esprit est la cause de la plasticité cérébrale? / Jean-Paul PES in Evolutions psychomotrices, 20-82 (Décembre 2008)
PermalinkAmeliorating the disadvantage for autistic job seekers: An initial evaluation of adapted employment interview questions / Katie MARAS in Autism, 25-4 (May 2021)
PermalinkAmélioration de la communication et de la socialisation par la Communication Facilitée chez 12 personnes autistes / Bruno GEPNER in Bulletin Scientifique de l'arapi (Le), 4 (décembre 1999)
PermalinkAmélioration du développement socio-émotionnel de jeunes enfants à risque d'un TSA dans un programme d'intervention neurodéveloppemental avec la Thérapie d'Echange et de Développement: étude pilote au Brésil / Camilla MAZETTO in Bulletin Scientifique de l'arapi (Le), 37 (Eté 2016)
PermalinkAméliorer l’avenir des personnes autistes par l’autonomie à La Spezia in Link Autisme-Europe, 67 (Juin 2017)
PermalinkAméliorer les compétences numériques / Catherine THEVENOT in Approche Neuropsychologique des Apprentissages chez l'Enfant - A.N.A.E., 123 (Septembre 2013)
PermalinkAméliorer les compétences numériques des enfants trisomiques 21: une question pédagogique et théorique / Guy CHAZOULE in Approche Neuropsychologique des Apprentissages chez l'Enfant - A.N.A.E., 120-121 (Novembre-Décembre 2012)
PermalinkAméliorer la compréhension en lecture chez les adultes avec une déficience intellectuelle : une intervention ciblée sur les processus cognitifs et métacognitifs et les stratégies d’apprentissage / S. BRANDON in Approche Neuropsychologique des Apprentissages chez l'Enfant - A.N.A.E., 139 (Décembre 2015)
PermalinkAméliorer la compréhension de textes descriptifs chez des élèves porteurs de TED / Florence CANET in Approche Neuropsychologique des Apprentissages chez l'Enfant - A.N.A.E., 123 (Septembre 2013)
PermalinkAméliorer le dialogue entre les sciences cognitives et l’éducation en s’inspirant des relations entre la recherche fondamentale et la médecine clinique / Elena PASQUINELLI in Approche Neuropsychologique des Apprentissages chez l'Enfant - A.N.A.E., 134 (Mars 2015)
PermalinkAméliorer les stratégies éducatives grâce à la formation: le projet Transfert / Monique DEPREZ in Nouvelle Revue de l'AIS (La), 60 (Janvier 2013)
PermalinkAménagement du domicile et Prestation de Compensation du Handicap / Anne TERLEZ in Rett Info, 66 (Hiver / Printemps 2009)
PermalinkL'aménagement : témoignages / COLLECTIF in Rett Info, 66 (Hiver / Printemps 2009)
PermalinkAménagements d’horaires : comment les négocier ? / Isabelle MALO in Déclic, 139 (Janver-Février 2011)
PermalinkAménagements d’horaires : mes collègues sont jaloux ! / Isabelle MALO in Déclic, 140 (Mars-Avril 2011)
PermalinkAménagements: monter et descendre les escaliers in Déclic, 147 (Mai-juin 2012)
PermalinkAménager chez soi ? Pas si compliqué ! / Vincent HUCHON in Déclic, 174 (Novembre-Décembre 2016)
PermalinkEt l'amendement Creton! in Rett Info, 58 (Automne/Hiver 2006)
PermalinkL'amendement gouvernemental de la honte qui fait disparaitre les Recommandations de l'évaluation de la qualité des ESMS et qui heureusement a été censuré par le Conseil Constitutionnel in Lettre d'Autisme France (La), 88 (Novembre 2021)
PermalinkAmniotic Fluid MMP-9 and Neurotrophins in Autism Spectrum Disorders: An Exploratory Study / Morsi W. ABDALLAH in Autism Research, 5-6 (December 2012)
PermalinkEn amont de l’illettrisme : repérer, dépister, traiter, un travail en partenariat / Jacques ROUSTIT in Approche Neuropsychologique des Apprentissages chez l'Enfant - A.N.A.E., 57 (Juin 2000)
PermalinkAmor and Social Stigma: ASD Beliefs Among Immigrant Mexican Parents / S. R. COHEN in Journal of Autism and Developmental Disorders, 48-6 (June 2018)
PermalinkL’amorçage syntaxique comme outil d’évaluation et de prise en charge des troubles du langage / Béatrice BOURDIN in Approche Neuropsychologique des Apprentissages chez l'Enfant - A.N.A.E., 166 (Juillet 2020)
PermalinkL’amour dans le poulailler / Isabelle MALO in Déclic, 141 (Mai-Juin 2011)
PermalinkAmour toujours? Une petite histoire de l'amour / Maryse ESTERLE in Aspiration, 8 (Mars 2016)
PermalinkAmplitude of low frequency fluctuations during resting state fMRI in autistic children / Kelly L. COBURN ; Meagan E. BECKERSON ; Rajesh K. KANA in Autism Research, 16-1 (January 2023)
PermalinkAmygdala, hippocampal and corpus callosum size following severe early institutional deprivation: The English and Romanian Adoptees Study Pilot / Mitul A. MEHTA in Journal of Child Psychology and Psychiatry, 50-8 (August 2009)
PermalinkAmygdala responses to threat in violence-exposed children depend on trauma context and maternal caregiving / Jennifer S. STEVENS in Development and Psychopathology, 35-3 (August 2023)
PermalinkAmygdala Volume Differences in Autism Spectrum Disorder Are Related to Anxiety / J. D. HERRINGTON in Journal of Autism and Developmental Disorders, 47-12 (December 2017)
PermalinkAn Abnormal Cerebellar Network in Children with Autistic Spectrum Disorder: A Morphometric Study / Alessandro GRECUCCI in Autism - Open Access, 6-3 ([01/05/2016])
PermalinkAn Acoustic Characterization of Prosodic Differences in Autism Spectrum Disorder and First-Degree Relatives / Shivani P. PATEL in Journal of Autism and Developmental Disorders, 50-8 (August 2020)
PermalinkAn affective dimension within oppositional defiant disorder symptoms among boys: personality and psychopathology outcomes into early adulthood / Jeffrey D. BURKE in Journal of Child Psychology and Psychiatry, 53-11 (November 2012)
PermalinkAn aggregate study of single-case research involving aided AAC: Participant characteristics of individuals with autism spectrum disorders / Jennifer B. GANZ in Research in Autism Spectrum Disorders, 5-4 (October-December 2011)
PermalinkAn amygdala-centered hyper-connectivity signature of threatening face processing predicts anxiety in youths with autism spectrum conditions / Y. C. CHEN in Autism Research, 14-11 (November 2021)
PermalinkAn analysis and review of the literature and a three-tier video modeling intervention model / Hui-Ting WANG in Research in Autism Spectrum Disorders, 8-7 (July 2014)
PermalinkAn Analysis of Canadian Institute for Health Research Funding for Research on Autism Spectrum Disorder / Raywat DEONANDAN in Autism Research and Treatment, 2016 (2016)
PermalinkAn analysis of reading abilities in children with autism spectrum disorders / Amanda NALLY in Research in Autism Spectrum Disorders, 47 (March 2018)
PermalinkAn Analysis of State Autism Educational Assessment Practices and Requirements / Erin E. BARTON in Journal of Autism and Developmental Disorders, 46-3 (March 2016)
PermalinkAn analysis of the effects of functional communication and a Voice Output Communication Aid for a child with autism spectrum disorder / Melissa L. OLIVE in Research in Autism Spectrum Disorders, 2-2 (April-June 2008)
PermalinkAn analysis of the predictors of comorbid psychopathology, gastrointestinal symptoms and epilepsy in children and adolescents with autism spectrum disorder / Arlene MANNION in Research in Autism Spectrum Disorders, 7-12 (December 2013)
PermalinkAn approach to head, neck and trunk stabilization and control in cerebral palsy by use of the Milwaukee brace / Mohinder A. MITAL in Developmental Medicine & Child Neurology, 18-2 (April 1976)
PermalinkAn Assessment and Instructional Guide for Motor and Vocal Imitation / E. ESPANOLA AGUIRRE in Journal of Autism and Developmental Disorders, 49-6 (June 2019)
PermalinkAn Assessment of the Benefits of Intrapartum Fetal Monitoring / Mary Y. ANTHONY in Developmental Medicine & Child Neurology, 32-6 (June 1990)
PermalinkAn Assessment of the Psychometric Properties of the GHQ-12 in an English Population of Autistic Adults Without Learning Difficulties / Emese MAYHEW in Journal of Autism and Developmental Disorders, 51-4 (April 2021)
PermalinkAn Association Between Serotonin 1A Receptor, Gray Matter Volume, and Sociability in Healthy Subjects and in Autism Spectrum Disorder / Arthur LEFEVRE in Autism Research, 13-11 (November 2020)
PermalinkAn association of intrapartum synthetic oxytocin dosing and the odds of developing autism / Stephen M. SOLTYS in Autism, 24-6 (August 2020)
PermalinkAn Association Study of Gamma-Aminobutyric Acid Type A Receptor Variants and Susceptibility to Autism Spectrum Disorders / P. ADAK in Journal of Autism and Developmental Disorders, 51-11 (November 2021)
PermalinkAn atlas of genetic correlations between gestational age and common psychiatric disorders / Yao YAO in Autism Research, 15-6 (June 2022)
PermalinkAn audit of the processes and tools used in different services across the South-West Region to diagnose Asperger syndrome in adults / Joe LOWENSTEIN in Good Autism Practice - GAP, 14-1 (May 2013)
PermalinkAn Australian Cross-Sectional Survey of Parents' Experiences of Emergency Department Visits Among Children with Autism Spectrum Disorder / Alice GARRICK in Journal of Autism and Developmental Disorders, 52-5 (May 2022)
PermalinkAn Autism Screening Expert System: Reliability, Validity and Factorial Structure / Maryam MAHMOUDI in Autism - Open Access, 8-3 ([01/06/2018])
PermalinkAn Autism Spectrum Disorders Forum: A Model for the Effective Use of Multidisciplinary Assessment and Intervention Planning with Limited Clinical Resources / Barry WRIGHT in Autism - Open Access, 6-4 ([01/07/2016])
PermalinkAn Autistic Child: The Vulnerable Patient: A Case Report / Hetal ACHARYA in Autism - Open Access, 4-2 ([01/03/2014])
PermalinkAn autistic dimension: A proposed subtype of obsessive-compulsive disorder / Susanne BEJEROT in Autism, 11-2 (March 2007)
PermalinkAn Auto ethnography of Parenting a Daughter whose Complex Disability was Diagnosed in her Adulthood / J. ALCOCK in Autism - Open Access, 6-5 ([01/09/2016])
PermalinkAn Early Social Engagement Intervention for Young Children with Autism and their Parents / Ty W. VERNON in Journal of Autism and Developmental Disorders, 42-12 (December 2012)
PermalinkAn Ecosystem Approach to Employment and Autism Spectrum Disorder / David B NICHOLAS in Journal of Autism and Developmental Disorders, 48-1 (January 2018)
PermalinkAn Effective Neurofeedback Intervention to Improve Social Interactions in Children with Autism Spectrum Disorder / Elisabeth V. C. FRIEDRICH in Journal of Autism and Developmental Disorders, 45-12 (December 2015)
PermalinkAn Effectiveness Study of a Culturally Enriched School-Based CBT Anxiety Prevention Program / Lynn D. MILLER in Journal of Clinical Child & Adolescent Psychology, 40-4 (July-August 2011)
PermalinkAn Electrophysiological Investigation of Interhemispheric Transfer Time in Children and Adolescents with High-Functioning Autism Spectrum Disorders / Ann CLAWSON in Journal of Autism and Developmental Disorders, 45-2 (February 2015)
PermalinkAn Electrophysiological Investigation of Semantic Incongruity Processing by People with Asperger’s Syndrome / Howard RING in Journal of Autism and Developmental Disorders, 37-2 (February 2007)
PermalinkAn elevated anxiety level among prepubertal autistic boys with non-treatment-seeking functional gastrointestinal disorders: A case-control study / O. W. H. WONG in Autism Research, 14-10 (October 2021)
PermalinkAn emerging income differential for adolescent emotional problems / Emma GORE LANGTON in Journal of Child Psychology and Psychiatry, 52-10 (October 2011)
PermalinkAn emotion recognition subtyping approach to studying the heterogeneity and comorbidity of autism spectrum disorders and attention-deficit/hyperactivity disorder / F. WADDINGTON in Journal of Neurodevelopmental Disorders, 10-1 (December 2018)
PermalinkAn Empirical Review of Peer-Mediated Interventions: Implications for Young Children With Autism Spectrum Disorders / Alison L. ZAGONA in Focus on Autism and Other Developmental Disabilities, 33-3 (September 2018)
PermalinkAn employer's guide to managing professionals on the autism spectrum / Glenys JONES in Good Autism Practice - GAP, 19-1 (May 2018)
PermalinkAn epidemiological study of ADHD symptoms among young persons and the relationship with cigarette smoking, alcohol consumption and illicit drug use / Gisli H. GUDJONSSON in Journal of Child Psychology and Psychiatry, 53-3 (March 2012)
PermalinkAn epidemiological study of cerebral palsy in Western Australia, 1956-1975. I: Changes in total incidence of cerebral palsy and associated factors / Fiona J. STANLEY in Developmental Medicine & Child Neurology, 21-6 (December 1979)
PermalinkAn epidemiological study of cerebral palsy in Western Australia, 1956-1975. II: Spastic cerebral palsy and perinatal factors / Alison DALE in Developmental Medicine & Child Neurology, 22-1 (February 1980)
PermalinkAn epidemiological study of cerebral palsy in Western Australia, 1956-1975. III: Postnatal aetiology / Eva BLAIR in Developmental Medicine & Child Neurology, 24-5 (October 1982)
PermalinkAn Epidemiological Study of Children's Attitudes Toward Disability / Susanne M. KING in Developmental Medicine & Child Neurology, 31-2 (April 1989)
PermalinkAn Epidemiological Study On Severe Mental Retardation Among Schoolchildren In Bologna, Italy / Giulia BENASSI in Developmental Medicine & Child Neurology, 32-10 (October 1990)
PermalinkAn epigenetic pathway approach to investigating associations between prenatal exposure to maternal mood disorder and newborn neurobehavior / E. CONRADT in Development and Psychopathology, 30-3 (August 2018)
PermalinkAn Evaluation of Behavioral Skills Training for Teaching Caregivers How to Support Social Skill Development in Their Child with Autism Spectrum Disorder / M. HASSAN in Journal of Autism and Developmental Disorders, 48-6 (June 2018)
PermalinkAn Evaluation of a Behaviorally Based Social Skills Group for Individuals Diagnosed with Autism Spectrum Disorder / Justin B. LEAF in Journal of Autism and Developmental Disorders, 47-2 (February 2017)
PermalinkAn evaluation of Chinese Orff Music Therapy for children with autism in China / Wolfgang MASTNAK in Good Autism Practice - GAP, 22-1 (May 2021)
PermalinkAn Evaluation of Early Development in Children with Autism and Pervasive Developmental Disorders from Home Movies: Preliminary Findings / Paola BERNABEI in Autism, 2-3 (September 1998)
PermalinkAn evaluation of EarlyBird and EarlyBird Plus over seven years: the benefits of parents and school staff being trained Together / Michelle CLUBB in Good Autism Practice - GAP, 13-1 (May 2012)
PermalinkAn Evaluation of Imitation Recognition Abilities in Typically Developing Children and Young Children with Autism Spectrum Disorder / Natalie I. BERGER in Autism Research, 8-4 (August 2015)
PermalinkAn evaluation of intervention research for transition-age autistic youth / Kristen BOTTEMA-BEUTEL in Autism, 27-4 (May 2023)
PermalinkAn evaluation of Miranda rights and interrogation in autism spectrum disorders / Lindsay M. SALSEDA in Research in Autism Spectrum Disorders, 5-1 (January-March 2011)
PermalinkAn Evaluation of Parent and Teacher Discrepancies on an Adaptive Behavior Measure for Youth with Autism Spectrum Disorder, Intellectual Disability, and Global Developmental Delay / Mallory A. STEVENS in Journal of Autism and Developmental Disorders, 53-7 (July 2023)
PermalinkAn Evaluation of a Parent Implemented In Situ Pedestrian Safety Skills Intervention for Individuals with Autism / Bethany HARRIAGE in Journal of Autism and Developmental Disorders, 46-6 (June 2016)
PermalinkAn evaluation of sensory diets and the impact on sensory processing, engagement and the wellbeing of autistic children / Bethany BARNSLEY in Good Autism Practice - GAP, 22-1 (May 2021)
PermalinkAn Evaluation of a Social Skills Intervention for Adults with Autism Spectrum Disorder and Intellectual Disabilities preparing for Employment in Ireland: A Pilot Study / E. WALSH in Journal of Autism and Developmental Disorders, 48-5 (May 2018)
PermalinkAn Evaluation of Specialist Mentoring for University Students with Autism Spectrum Disorders and Mental Health Conditions / R. LUCAS in Journal of Autism and Developmental Disorders, 48-3 (March 2018)
PermalinkAn evaluation of a stepped-care telehealth program for improving the sleep of autistic children / Monique A. C. CLARKE in Research in Autism Spectrum Disorders, 112 (April 2024)
PermalinkAn evaluation of strategies for training staff to implement the picture exchange communication system / Clarissa S. BARNES in Research in Autism Spectrum Disorders, 5-4 (October-December 2011)
PermalinkAn evaluation of a swimming toolkit for children on the autism spectrum / Julie EARL in Good Autism Practice - GAP, 11-2 (October 2010)
PermalinkAn Evaluation of the Applicability of the Tripartite Constructs to Social Anxiety in Adolescents / Emily R. ANDERSON in Journal of Clinical Child & Adolescent Psychology, 39-2 (March-April 2010)
PermalinkAn evaluation of the Attention Autism programme for secondary aged children with autism in a mainstream setting / Leah MCKEOWN in Good Autism Practice - GAP, 16-1 (May 2015)
PermalinkAn Evaluation of the Autism Education Trust's Progression Framework in Three Mainstream Primary Schools / Caroline O'REILLY in Good Autism Practice - GAP, 20-1 (May 2019)
PermalinkAn evaluation of the components of a Social Stories™ intervention package / Jeannette M. ISKANDER in Research in Autism Spectrum Disorders, 7-1 (January 2013)
PermalinkAn evaluation of the Cygnet parenting support programme for parents of children with autism spectrum conditions / Lucy STUTTARD in Research in Autism Spectrum Disorders, 23 (March 2016)
PermalinkAn evaluation of the diagnostic validity of the structured questionnaires of the adult Asperger?s Assessment / Anna JONES in Journal of Autism and Developmental Disorders, 53-7 (July 2023)
PermalinkAn Evaluation of the Quality of Research on Evidence-Based Practices for Daily Living Skills for Individuals with Autism Spectrum Disorder / Ee Rea HONG in Journal of Autism and Developmental Disorders, 45-9 (September 2015)
PermalinkAn evaluation of the use of advocacy with an adult seeking a diagnostic assessment for Asperger syndrome / Gillian QUINN in Good Autism Practice - GAP, 10-1 (May 2009)
PermalinkAn evaluation of a tool, based on spoon theory, to promote self-regulation and avoidance of burnout in autistic children and young people / Karen MCGUINNESS in Good Autism Practice - GAP, 22-1 (May 2021)
PermalinkAn evaluation of a visualy presented narrative play intervention on the functional play and expressive communication skills of young children with autism / Emma PUTTOCK in Good Autism Practice - GAP, 16-2 (October 2015)
PermalinkAn evaluation of wayfinding abilities in adolescent and young adult males with autism spectrum disorder / Yingying YANG in Research in Autism Spectrum Disorders, 80 (February 2021)
PermalinkAn even more radical change is needed in our autism research strategy: Comments on Mottron (2021) / Y. LEVY in Autism Research, 14-10 (October 2021)
PermalinkAn event-related potential and behavioral study of impaired inhibitory control in children with autism spectrum disorder / Chia-Liang TSAI in Research in Autism Spectrum Disorders, 5-3 (July-September 2011)
PermalinkAn Evidence-Based Practice Synthesis of Virtual Manipulatives for Students With ASD and IDD / Holly M. LONG in Focus on Autism and Other Developmental Disabilities, 38-3 (September 2023)
PermalinkAn examination of autism spectrum traits in adolescents with anorexia nervosa and their parents / Charlotte RHIND in Molecular Autism, (December 2014)
PermalinkAn examination of challenging behaviors in autistic disorder versus pervasive developmental disorder not otherwise specified: Significant differences and gender effects / Alison M. KOZLOWSKI in Research in Autism Spectrum Disorders, 6-1 (January-March 2012)
PermalinkAn Examination of Education Professionals’ Beliefs About Causes of Autism and Their Perceptions of Practices / Veronica P. FLEURY in Focus on Autism and Other Developmental Disabilities, 37-3 (September 2022)
PermalinkAn examination of father vulnerability and coercive family process after the birth of a sibling: A spillover cascade model / Matthew M. STEVENSON in Development and Psychopathology, 31-2 (May 2019)
PermalinkAn Examination of Handedness and Footedness in Children with High Functioning Autism and Asperger Syndrome / R. MARKOULAKIS in Journal of Autism and Developmental Disorders, 42-10 (October 2012)
PermalinkAn Examination of Iconic Memory in Children with Autism Spectrum Disorders / Carly A. MCMORRIS in Journal of Autism and Developmental Disorders, 43-8 (August 2013)
PermalinkAn examination of maternal prenatal BMI and human fetal brain development / Megan E. NORR in Journal of Child Psychology and Psychiatry, 62-4 (April 2021)
PermalinkAn examination of reciprocal associations between substance use and effortful control across adolescence using a bifactor model of externalizing symptoms / Katie J. PAIGE in Development and Psychopathology, 33-4 (October 2021)
PermalinkAn examination of response variability in children with autism and the relationship to restricted repetitive behavior subtypes / Clodagh MURRAY in Research in Autism Spectrum Disorders, 11 (March 2015)
PermalinkAn Examination of Social Skills, Friendship Quality, and Loneliness for Adults with Williams Syndrome / Marisa H FISHER in Journal of Autism and Developmental Disorders, 50-10 (October 2020)
PermalinkAn examination of the joint effects of adolescent interpersonal styles and parenting styles on substance use / Samuel N. MEISEL in Development and Psychopathology, 34-3 (August 2022)
PermalinkAn examination of the relationship between communication and socialization deficits in children with autism and PDD-NOS / Megan A. HATTIER in Research in Autism Spectrum Disorders, 6-2 (April-June 2012)
PermalinkAn examination of the reliability of a new observation measure for autism spectrum disorders: The autism spectrum disorder observation for children / Daniene NEAL in Research in Autism Spectrum Disorders, 7-1 (January 2013)
PermalinkAn Examination of the Tripartite Model of Depressive and Anxiety Symptoms in African American Youth: Stressors and Coping Strategies as Common and Specific Correlates / Noni K. GAYLORD-HARDEN in Journal of Clinical Child & Adolescent Psychology, 40-3 (May-June 2011)
PermalinkAn experimental analysis of the effects of therapeutic horseback riding on the behavior of children with autism / Sarah R. JENKINS in Research in Autism Spectrum Disorders, 7-6 (June 2013)
PermalinkAn Experimental Investigation of Peer Influences on Adolescent Hostile Attributions / Kim FREEMAN in Journal of Clinical Child & Adolescent Psychology, 40-6 (November-December 2011)
PermalinkAn experimental study of executive function and social impairment in Cornelia de Lange syndrome / L. NELSON in Journal of Neurodevelopmental Disorders, 9-1 (December 2017)
PermalinkAn experimental study of word learning in minimally verbal children and adolescents with autism spectrum disorder / Robert M. JOSEPH in Autism & Developmental Language Impairments, 4 (January-December 2019)
PermalinkAn experimental test of differential susceptibility to parenting among emotionally-dysregulated children in a randomized controlled trial for oppositional behavior / Stephen SCOTT in Journal of Child Psychology and Psychiatry, 53-11 (November 2012)
PermalinkAn experimental test of parenting practices as a mediator of early childhood physical aggression / Laurie MILLER BROTMAN in Journal of Child Psychology and Psychiatry, 50-3 (March 2009)
PermalinkAn experimental test of the fetal programming hypothesis: Can we reduce child ontogenetic vulnerability to psychopathology by decreasing maternal depression? / E. P. DAVIS in Development and Psychopathology, 30-3 (August 2018)
PermalinkAn exploration of dimensions of early adversity and the development of functional brain network connectivity during adolescence: Implications for trajectories of internalizing symptoms / Rajpreet CHAHAL in Development and Psychopathology, 34-2 (May 2022)
PermalinkAn Exploration of Imitation Recognition in Young Children With Autism Spectrum Disorders / Natalie I. BERGER in Autism Research, 6-5 (October 2013)
PermalinkAn Exploration of Law Enforcement Officers' Training Needs and Interactions with Individuals with Autism Spectrum Disorder / Kirsten S. RAILEY in Journal of Autism and Developmental Disorders, 50-1 (January 2020)
PermalinkAn Exploration of Physical and Phenotypic Characteristics of Bangladeshi Children with Autism Spectrum Disorder / M. A. RAHAMAN in Journal of Autism and Developmental Disorders, 51-7 (July 2021)
PermalinkAn Exploration of Social Cognition in Children with Different Degrees of Genetic Deletion in Williams Syndrome / Carlos Alberto SERRANO-JUAREZ in Journal of Autism and Developmental Disorders, 51-5 (May 2021)
PermalinkAn exploration of the judgement of sexual situations by adolescents with autism spectrum disorders versus typically developing adolescents / Kirsten VISSER in Research in Autism Spectrum Disorders, 36 (April 2017)
PermalinkAn exploration of the Pathological (or Extreme) Demand Avoidant profile in children referred for an autism diagnostic assessment using data from ADOS-2 assessments and their developmental histories / Judy EATON in Good Autism Practice - GAP, 21-2 (October 2020)
PermalinkAn Explorative Study of Atypical Social Interaction Styles in Adult Men with Autism Spectrum Disorder, Men with Personality Disorders and Men from the General Population / Richard VUIJK ; Pieter de Nijs ; Arnoud ARNTZ ; Hilde M. GEURTS in Journal of Autism and Developmental Disorders, 53-6 (June 2023)
PermalinkAn Exploratory Analysis of Predictors of Youth Suicide-Related Behaviors in Autism Spectrum Disorder: Implications for Prevention Science / Christina G. MCDONNELL in Journal of Autism and Developmental Disorders, 50-10 (October 2020)
PermalinkAn Exploratory Analysis of the Impact of Family Functioning on Treatment for Depression in Adolescents / Norah C. FEENY in Journal of Clinical Child & Adolescent Psychology, 38-6 (November-December 2009)
PermalinkAn exploratory longitudinal study of social and language outcomes in children with autism in bilingual home environments / V. ZHOU in Autism, 23-2 (February 2019)
PermalinkAn Exploratory Study of Autism Traits and Parenting / Cheryl DISSANAYAKE in Journal of Autism and Developmental Disorders, 50-7 (July 2020)
PermalinkAn Exploratory Study of a Dimensional Assessment of the Diagnostic Criteria for Autism / Mark BROSNAN in Journal of Autism and Developmental Disorders, 50-11 (November 2020)
PermalinkAn Exploratory Study of Imagining Sounds and "Hearing" Music in Autism / Alex BACON in Journal of Autism and Developmental Disorders, 50-4 (April 2020)
PermalinkAn exploratory study of the association between reactive attachment disorder and attachment narratives in early school-age children / Helen MINNIS in Journal of Child Psychology and Psychiatry, 50-8 (August 2009)
PermalinkAn Exploratory Study Using Science eTexts With Students With Autism Spectrum Disorder / Victoria F. KNIGHT in Focus on Autism and Other Developmental Disabilities, 30-2 (June 2015)
PermalinkAn Exploratory Trial of Transdermal Nicotine for Aggression and Irritability in Adults with Autism Spectrum Disorder / A. S. LEWIS in Journal of Autism and Developmental Disorders, 48-8 (August 2018)
PermalinkAn extended Family with a Dominantly Inherited Speech Disorder / J. A. HURST in Developmental Medicine & Child Neurology, 32-4 (April 1990)
PermalinkAn extended functional analysis protocol assesses the role of stereotypy in aggression in two young children with autism spectrum disorder / Pamela J. WHITE in Research in Autism Spectrum Disorders, 5-2 (April-June 2011)
PermalinkAn Eye-Movement Study of relational Memory in Adults with Autism Spectrum Disorder / Melanie RING in Journal of Autism and Developmental Disorders, 47-10 (October 2017)
PermalinkAn fMRI examination of developmental differences in the neural correlates of uncertainty and decision-making / Amy L. KRAIN in Journal of Child Psychology and Psychiatry, 47-10 (October 2006)
PermalinkAn fMRI study of facial emotion processing in children and adolescents with 22q11.2 deletion syndrome / R. AZUMA in Journal of Neurodevelopmental Disorders, 7-1 (December 2015)
PermalinkAn In-Depth Analysis of Expository Writing in Children With and Without Autism Spectrum Disorder / E. HILVERT in Journal of Autism and Developmental Disorders, 49-8 (August 2019)
PermalinkAn in-depth examination of optimal outcome children with a history of autism spectrum disorders / Elizabeth KELLEY in Research in Autism Spectrum Disorders, 4-3 (July-September 2010)
PermalinkAn Indirect Examination of the Function of Problem Behavior Associated with Fragile X Syndrome and Smith-Magenis Syndrome / Paul LANGTHORNE in Journal of Autism and Developmental Disorders, 42-2 (February 2012)
PermalinkAn Initial Development and Evaluation of a Culturally Responsive Police Interactions Training for Black Adolescents with Autism Spectrum Disorder / Mattina A. DAVENPORT in Journal of Autism and Developmental Disorders, 53-4 (April 2023)
PermalinkAn Initial Examination of Post-Traumatic Stress Disorder in Mothers of Children with Autism Spectrum Disorder: Challenging Child Behaviors as Criterion A Traumatic Stressors / Alexandra SCHNABEL in Autism Research, 13-9 (September 2020)
PermalinkAn Initial Investigation of the Generalization of a School-Based Social Competence Intervention for Youth with High-Functioning Autism / Carla SCHMIDT in Autism Research and Treatment, (September 2011)
PermalinkAn initial psychometric evaluation of the CBCL 6–18 in a sample of youth with autism spectrum disorders / Vincent PANDOLFI in Research in Autism Spectrum Disorders, 6-1 (January-March 2012)
PermalinkAn Initial Psychometric Evaluation of the Joint Attention Protocol / Sallie W. NOWELL in Journal of Autism and Developmental Disorders, 48-6 (June 2018)
PermalinkAn initial trial of OPT-In-Early: An online training program for caregivers of autistic children / Yael G DAI in Autism, 27-6 (August 2023)
PermalinkAn Innovative Approach to Development of Social Abilities in Individuals with Autism: A Pilot Study / Monica MAZZA in Autism - Open Access, 6-1 ([01/01/2016])
PermalinkAn Instrument to Prepare for Acute Care of the Individual with Autism Spectrum Disorder in the Emergency Department / Arvind VENKAT in Journal of Autism and Developmental Disorders, 46-7 (July 2016)
PermalinkAn Integrated view of the Molecular Toxinology of Sodium Channel Gating in Excitable Cells / Gary STRICHARTZ in Annual Review of Neuroscience, 10 (1987)
PermalinkAn integrative evolutionary framework for psychopathology / Marco DEL GIUDICE in Development and Psychopathology, 35-1 (February 2023)
PermalinkAn interaction between early threat exposure and the oxytocin receptor in females: Disorder-specific versus general risk for psychopathology and social–emotional mediators / Amy L. BYRD in Development and Psychopathology, 33-4 (October 2021)
PermalinkAn International Clinical Study of Ability and Disability in Autism Spectrum Disorder Using the WHO-ICF Framework / S. MAHDI in Journal of Autism and Developmental Disorders, 48-6 (June 2018)
Permalink