Dépouillements

Editorial: Schools on the frontline of suicide prevention / Rebecca C. KAMODY in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.833-835 Titre : Editorial: Schools on the frontline of suicide prevention Type de document : Texte imprimé et/ou numérique Auteurs : Rebecca C. KAMODY, Auteur ; Michael H. BLOCH, Auteur Article en page(s) : p.833-835 Langues : Anglais (eng) Mots-clés : Adolescent  COVID-19/prevention & control  Child  Humans  Mental Health Services  Pandemics  Schools  Suicide/prevention & control/psychology  United States Index. décimale : PER Périodiques Résumé : The world has experienced an unprecedented mental health crisis associated with the COVID-19 pandemic (Liu et al., 2020). After more than two years navigating the associated uncertainty and distress, the impact on youth mental health continues to be a pressing concern. Those in the mental health field, as well as the children and families plagued by its impact, are inundated with seeing firsthand the impact on youth's functioning. This includes increases in depression and suicide (Asarnow & Chung, 2021; Manzar et al., 2021), and having to navigate siloes in care and often even an inability when in crisis to access a continuum of services (Zhai, 2021). This has highlighted the significant issues with accessibility of mental health care and inequitable access to care for youth mental health both in the United States and globally. We continue to experience daily the impact of insufficient resources for youth behavioral health. For those in the field who prioritize the need for more robust intervention approaches, the child mental health crisis associated with the pandemic has highlighted the need for us to develop more novel and innovative interventions. En ligne : http://dx.doi.org/10.1111/jcpp.13663 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 [article] Editorial: Schools on the frontline of suicide prevention [Texte imprimé et/ou numérique] / Rebecca C. KAMODY, Auteur ; Michael H. BLOCH, Auteur . - p.833-835. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.833-835 Mots-clés : Adolescent  COVID-19/prevention & control  Child  Humans  Mental Health Services  Pandemics  Schools  Suicide/prevention & control/psychology  United States Index. décimale : PER Périodiques Résumé : The world has experienced an unprecedented mental health crisis associated with the COVID-19 pandemic (Liu et al., 2020). After more than two years navigating the associated uncertainty and distress, the impact on youth mental health continues to be a pressing concern. Those in the mental health field, as well as the children and families plagued by its impact, are inundated with seeing firsthand the impact on youth's functioning. This includes increases in depression and suicide (Asarnow & Chung, 2021; Manzar et al., 2021), and having to navigate siloes in care and often even an inability when in crisis to access a continuum of services (Zhai, 2021). This has highlighted the significant issues with accessibility of mental health care and inequitable access to care for youth mental health both in the United States and globally. We continue to experience daily the impact of insufficient resources for youth behavioral health. For those in the field who prioritize the need for more robust intervention approaches, the child mental health crisis associated with the pandemic has highlighted the need for us to develop more novel and innovative interventions. En ligne : http://dx.doi.org/10.1111/jcpp.13663 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486

Research Review: The effect of school-based suicide prevention on suicidal ideation and suicide attempts and the role of intervention and contextual factors among adolescents: a meta-analysis and meta-regression / Eibhlin H. WALSH in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.836-845 Titre : Research Review: The effect of school-based suicide prevention on suicidal ideation and suicide attempts and the role of intervention and contextual factors among adolescents: a meta-analysis and meta-regression Type de document : Texte imprimé et/ou numérique Auteurs : Eibhlin H. WALSH, Auteur ; Jennifer MCMAHON, Auteur ; Matthew P. HERRING, Auteur Article en page(s) : p.836-845 Langues : Anglais (eng) Mots-clés : Adolescent  Humans  Incidence  School Health Services  Schools  Suicidal Ideation  Suicide, Attempted/prevention & control  Suicidal thoughts and behaviours  adolescence  meta-analysis  post-primary school-based suicide prevention Index. décimale : PER Périodiques Résumé : BACKGROUND: Globally, suicide is the fourth highest cause of adolescent mortality (Suicide: https://www.who.int/news-room/fact-sheets/detail/suicide). The effects of post-primary school-based suicide prevention (PSSP) on adolescent suicidal thoughts and behaviours (STBs) have not been comprehensively synthesised. We aim to estimate the population effect for PSSP interventions on adolescent STBs and explore how intervention effects vary based on intervention and contextual moderators. METHODS: Searches of PsycINFO, Medline, Education Source, ERIC, Web of Science, and the Cochrane Central Register of Controlled Trials identified cluster randomised trials examining the effectiveness of PSSP on adolescent STBs. The Cochrane Risk of Bias tool assessed bias. Crude and adjusted back-transformed odds ratios (ORs) were calculated. Multilevel random-effects models accounted for dependencies of effects. Univariate meta-regression explored variability of intervention and contextual moderators on pooled effects. RESULTS: There were 19 and 12 effects for suicidal ideation (SI) and suicide attempts (SA). Compared with controls, interventions were associated with 13% (OR=0.87, 95%CI [0.78, 0.96]) and 34% (OR=0.66, 95%CI [0.47, 0.91]) lower crude odds reductions for SI and SA, respectively. Effects were similar for adjusted SI (OR = 0.85, 95%CI [0.75, 0.95]) and SA (OR = 0.72, 95%CI [0.59, 0.87]) models. Within-study (0.20-9.10%) and between-study (0-51.20%) heterogeneity ranged for crude and adjusted SA models and SI heterogeneity was 0%. Moderator analyses did not vary SA effects (ps>.05). CONCLUSIONS: This meta-analysis contributes to the PSSP evidence-base by demonstrating that PSSP targeting STBs as both primary intervention outcomes and with other health and well-being outcomes reduced SI and SA among 33,155 adolescents attending 329 schools, compared to controls. The number needed to treat estimates suggests the potential of reducing the incidence of SA and SI in one adolescent by implementing PSSP in 1-2 classrooms, supporting PSSP as a clinically relevant suicide prevention strategy. Although moderator analyses were nonsignificant and contained a small number of trials, larger SA effect sizes support particular effectiveness for interventions of a duration of 1week, involving multiple stakeholders and with a 12-month follow-up. En ligne : http://dx.doi.org/10.1111/jcpp.13598 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 [article] Research Review: The effect of school-based suicide prevention on suicidal ideation and suicide attempts and the role of intervention and contextual factors among adolescents: a meta-analysis and meta-regression [Texte imprimé et/ou numérique] / Eibhlin H. WALSH, Auteur ; Jennifer MCMAHON, Auteur ; Matthew P. HERRING, Auteur . - p.836-845. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.836-845 Mots-clés : Adolescent  Humans  Incidence  School Health Services  Schools  Suicidal Ideation  Suicide, Attempted/prevention & control  Suicidal thoughts and behaviours  adolescence  meta-analysis  post-primary school-based suicide prevention Index. décimale : PER Périodiques Résumé : BACKGROUND: Globally, suicide is the fourth highest cause of adolescent mortality (Suicide: https://www.who.int/news-room/fact-sheets/detail/suicide). The effects of post-primary school-based suicide prevention (PSSP) on adolescent suicidal thoughts and behaviours (STBs) have not been comprehensively synthesised. We aim to estimate the population effect for PSSP interventions on adolescent STBs and explore how intervention effects vary based on intervention and contextual moderators. METHODS: Searches of PsycINFO, Medline, Education Source, ERIC, Web of Science, and the Cochrane Central Register of Controlled Trials identified cluster randomised trials examining the effectiveness of PSSP on adolescent STBs. The Cochrane Risk of Bias tool assessed bias. Crude and adjusted back-transformed odds ratios (ORs) were calculated. Multilevel random-effects models accounted for dependencies of effects. Univariate meta-regression explored variability of intervention and contextual moderators on pooled effects. RESULTS: There were 19 and 12 effects for suicidal ideation (SI) and suicide attempts (SA). Compared with controls, interventions were associated with 13% (OR=0.87, 95%CI [0.78, 0.96]) and 34% (OR=0.66, 95%CI [0.47, 0.91]) lower crude odds reductions for SI and SA, respectively. Effects were similar for adjusted SI (OR = 0.85, 95%CI [0.75, 0.95]) and SA (OR = 0.72, 95%CI [0.59, 0.87]) models. Within-study (0.20-9.10%) and between-study (0-51.20%) heterogeneity ranged for crude and adjusted SA models and SI heterogeneity was 0%. Moderator analyses did not vary SA effects (ps>.05). CONCLUSIONS: This meta-analysis contributes to the PSSP evidence-base by demonstrating that PSSP targeting STBs as both primary intervention outcomes and with other health and well-being outcomes reduced SI and SA among 33,155 adolescents attending 329 schools, compared to controls. The number needed to treat estimates suggests the potential of reducing the incidence of SA and SI in one adolescent by implementing PSSP in 1-2 classrooms, supporting PSSP as a clinically relevant suicide prevention strategy. Although moderator analyses were nonsignificant and contained a small number of trials, larger SA effect sizes support particular effectiveness for interventions of a duration of 1week, involving multiple stakeholders and with a 12-month follow-up. En ligne : http://dx.doi.org/10.1111/jcpp.13598 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486

Displays of negative facial affect during parent-adolescent conflict and the bidirectional transmission of social anxiety / Mary L. WOODY in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.846-854 Titre : Displays of negative facial affect during parent-adolescent conflict and the bidirectional transmission of social anxiety Type de document : Texte imprimé et/ou numérique Auteurs : Mary L. WOODY, Auteur ; Aleksandra KAURIN, Auteur ; Kirsten M. P. MCKONE, Auteur ; Cecile D. LADOUCEUR, Auteur ; Jennifer S. SILK, Auteur Article en page(s) : p.846-854 Langues : Anglais (eng) Mots-clés : Adolescent  Anxiety  Facial Expression  Fear  Female  Humans  Parent-Child Relations  Parenting/psychology  Parents/psychology  Adolescence  facial expression  parent-child interaction  structural equation modeling Index. décimale : PER Périodiques Résumé : BACKGROUND: Symptoms of social anxiety rise rapidly during adolescence, particularly for girls. Pervasive displays of parental negative affect may increase adolescents' fear of negative evaluation (FNE), thereby increasing risk for social anxiety symptoms. Adolescent displays of negative affect may also exacerbate parents' social anxiety symptoms (via FNE of their child or their parenting skills), yet little research has tested transactional pathways of transmission in families. By early adolescence, rates of parent-child conflict rise, and offspring become increasingly independent in their own displays of negative affect, increasing opportunities for hypothesized transactional pathways between parent-adolescent displays of negative affect and social anxiety symptoms. METHODS: This study included 129 parents and daughters (11-13; no baseline social anxiety disorder), two-thirds of whom were at high risk for social anxiety due to a shy/fearful temperament. We used actor-partner interdependence models (APIM) to test whether displays of negative facial affect, assessed individually for each parent and daughter during a conflict discussion, would predict their partner's social anxiety symptoms two years later. Automated facial affect coding assessed the frequency of negative affect during the discussion. Clinician ratings of social anxiety symptoms were completed at baseline and two-year follow-up. RESULTS: Both parents and daughters who displayed more frequent negative facial affect at baseline had partners with higher follow-up social anxiety symptoms, an effect that was maintained after accounting for actors' and partners' baseline symptoms. CONCLUSIONS: Findings are consistent with intergenerational models positing that parental negative affective behaviors increase risk for adolescent social anxiety symptoms but also suggest that adolescent negative facial affect may exacerbate parental social anxiety symptoms. These bidirectional effects improve understanding of how social anxiety is maintained within a transactional family structure and highlight that displays of negative affect during parent-adolescent interaction may warrant future examination as a potential treatment target for adolescent social anxiety. En ligne : http://dx.doi.org/10.1111/jcpp.13530 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 [article] Displays of negative facial affect during parent-adolescent conflict and the bidirectional transmission of social anxiety [Texte imprimé et/ou numérique] / Mary L. WOODY, Auteur ; Aleksandra KAURIN, Auteur ; Kirsten M. P. MCKONE, Auteur ; Cecile D. LADOUCEUR, Auteur ; Jennifer S. SILK, Auteur . - p.846-854. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.846-854 Mots-clés : Adolescent  Anxiety  Facial Expression  Fear  Female  Humans  Parent-Child Relations  Parenting/psychology  Parents/psychology  Adolescence  facial expression  parent-child interaction  structural equation modeling Index. décimale : PER Périodiques Résumé : BACKGROUND: Symptoms of social anxiety rise rapidly during adolescence, particularly for girls. Pervasive displays of parental negative affect may increase adolescents' fear of negative evaluation (FNE), thereby increasing risk for social anxiety symptoms. Adolescent displays of negative affect may also exacerbate parents' social anxiety symptoms (via FNE of their child or their parenting skills), yet little research has tested transactional pathways of transmission in families. By early adolescence, rates of parent-child conflict rise, and offspring become increasingly independent in their own displays of negative affect, increasing opportunities for hypothesized transactional pathways between parent-adolescent displays of negative affect and social anxiety symptoms. METHODS: This study included 129 parents and daughters (11-13; no baseline social anxiety disorder), two-thirds of whom were at high risk for social anxiety due to a shy/fearful temperament. We used actor-partner interdependence models (APIM) to test whether displays of negative facial affect, assessed individually for each parent and daughter during a conflict discussion, would predict their partner's social anxiety symptoms two years later. Automated facial affect coding assessed the frequency of negative affect during the discussion. Clinician ratings of social anxiety symptoms were completed at baseline and two-year follow-up. RESULTS: Both parents and daughters who displayed more frequent negative facial affect at baseline had partners with higher follow-up social anxiety symptoms, an effect that was maintained after accounting for actors' and partners' baseline symptoms. CONCLUSIONS: Findings are consistent with intergenerational models positing that parental negative affective behaviors increase risk for adolescent social anxiety symptoms but also suggest that adolescent negative facial affect may exacerbate parental social anxiety symptoms. These bidirectional effects improve understanding of how social anxiety is maintained within a transactional family structure and highlight that displays of negative affect during parent-adolescent interaction may warrant future examination as a potential treatment target for adolescent social anxiety. En ligne : http://dx.doi.org/10.1111/jcpp.13530 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486

Using tissue microstructure and multimodal MRI to parse the phenotypic heterogeneity and cellular basis of autism spectrum disorder / Bradley S. PETERSON in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.855-870 Titre : Using tissue microstructure and multimodal MRI to parse the phenotypic heterogeneity and cellular basis of autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Bradley S. PETERSON, Auteur ; Jiaqi LIU, Auteur ; Louis DANTEC, Auteur ; Courtney NEWMAN, Auteur ; Siddhant SAWARDEKAR, Auteur ; Suzanne GOH, Auteur ; Ravi BANSAL, Auteur Article en page(s) : p.855-870 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/metabolism  Brain/metabolism  Diffusion Tensor Imaging  Humans  Magnetic Resonance Imaging  White Matter/diagnostic imaging/pathology  Autism  white matter  interest. Index. décimale : PER Périodiques Résumé : BACKGROUND: Identifying the brain bases for phenotypic heterogeneity in Autism Spectrum Disorder (ASD) will advance understanding of its pathogenesis and improve its clinical management. METHODS: We compared Diffusion Tensor Imaging (DTI) indices and connectome measures between 77 ASD and 88 Typically Developing (TD) control participants. We also assessed voxel-wise associations of DTI indices with measures of regional cerebral blood flow (rCBF) and N-acetylaspartate (NAA) to understand how tissue microstructure associates with cellular metabolism and neuronal density, respectively. RESULTS: Autism Spectrum Disorder participants had significantly lower fractional anisotropy (FA) and higher diffusivity values in deep white matter tracts, likely representing ether reduced myelination by oligodendrocytes or a reduced density of myelinated axons. Greater abnormalities in these measures and regions were associated with higher ASD symptom scores. Participant age, sex and IQ significantly moderated these group differences. Path analyses showed that reduced NAA levels accounted significantly for higher diffusivity and higher rCBF values in ASD compared with TD participants. CONCLUSIONS: Reduced neuronal density (reduced NAA) likely underlies abnormalities in DTI indices of white matter microstructure in ASD, which in turn are major determinants of elevated blood flow. Together, these findings suggest the presence of reduced axonal density and axonal pathology in ASD white matter. Greater pathology in turn accounts for more severe symptoms, lower intellectual ability, and reduced global efficiency for measures of white matter connectivity in ASD. En ligne : http://dx.doi.org/10.1111/jcpp.13531 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 [article] Using tissue microstructure and multimodal MRI to parse the phenotypic heterogeneity and cellular basis of autism spectrum disorder [Texte imprimé et/ou numérique] / Bradley S. PETERSON, Auteur ; Jiaqi LIU, Auteur ; Louis DANTEC, Auteur ; Courtney NEWMAN, Auteur ; Siddhant SAWARDEKAR, Auteur ; Suzanne GOH, Auteur ; Ravi BANSAL, Auteur . - p.855-870. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.855-870 Mots-clés : Autism Spectrum Disorder/metabolism  Brain/metabolism  Diffusion Tensor Imaging  Humans  Magnetic Resonance Imaging  White Matter/diagnostic imaging/pathology  Autism  white matter  interest. Index. décimale : PER Périodiques Résumé : BACKGROUND: Identifying the brain bases for phenotypic heterogeneity in Autism Spectrum Disorder (ASD) will advance understanding of its pathogenesis and improve its clinical management. METHODS: We compared Diffusion Tensor Imaging (DTI) indices and connectome measures between 77 ASD and 88 Typically Developing (TD) control participants. We also assessed voxel-wise associations of DTI indices with measures of regional cerebral blood flow (rCBF) and N-acetylaspartate (NAA) to understand how tissue microstructure associates with cellular metabolism and neuronal density, respectively. RESULTS: Autism Spectrum Disorder participants had significantly lower fractional anisotropy (FA) and higher diffusivity values in deep white matter tracts, likely representing ether reduced myelination by oligodendrocytes or a reduced density of myelinated axons. Greater abnormalities in these measures and regions were associated with higher ASD symptom scores. Participant age, sex and IQ significantly moderated these group differences. Path analyses showed that reduced NAA levels accounted significantly for higher diffusivity and higher rCBF values in ASD compared with TD participants. CONCLUSIONS: Reduced neuronal density (reduced NAA) likely underlies abnormalities in DTI indices of white matter microstructure in ASD, which in turn are major determinants of elevated blood flow. Together, these findings suggest the presence of reduced axonal density and axonal pathology in ASD white matter. Greater pathology in turn accounts for more severe symptoms, lower intellectual ability, and reduced global efficiency for measures of white matter connectivity in ASD. En ligne : http://dx.doi.org/10.1111/jcpp.13531 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486

Maternal caregiving moderates the impact of antenatal maternal cortisol on infant stress regulation / Sarah NAZZARI in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.871-880 Titre : Maternal caregiving moderates the impact of antenatal maternal cortisol on infant stress regulation Type de document : Texte imprimé et/ou numérique Auteurs : Sarah NAZZARI, Auteur ; Richard M. PASCO FEARON, Auteur ; Frances RICE, Auteur ; Massimo MOLTENI, Auteur ; Alessandra FRIGERIO, Auteur Article en page(s) : p.871-880 Langues : Anglais (eng) Mots-clés : Adult  Anxiety  Depression/psychology  Depression, Postpartum  Female  Humans  Hydrocortisone/metabolism  Infant  Male  Mother-Child Relations/psychology  Mothers/psychology  Pregnancy  Saliva  Stress, Psychological/psychology  Cortisol  alpha-amylase  caregiving  inflammation  stress Index. décimale : PER Périodiques Résumé : BACKGROUND: Emerging evidence suggests that antenatal exposure to maternal stress signals affects the development of the infant stress response systems. Animal studies indicate that maternal sensitive caregiving can reverse some of these effects. However, the generalizability of these findings to humans is unknown. This study investigated the role of maternal caregiving in the association between multiple markers of maternal antenatal stress and infant stress regulation. METHODS: The sample consisted of 94 mother-infant (N=47 males, mean postnatal weeks=12; SD=1.84) dyads. Maternal levels of Interleukin-6, C-Reactive Protein (CRP), diurnal cortisol and alpha amylase, depressive and anxiety symptoms were assessed in late pregnancy (mean gestational age=34.76; SD=1.12), whereas postnatal symptomatology, caregiving, and infant cortisol response to the inoculation were evaluated at 3months. RESULTS: Hierarchical linear models (HLMs) showed a significant interaction between maternal antenatal cortisol, caregiving, and time on infant cortisol reactivity, while controlling for gender, maternal age, and postnatal depression. Specifically, higher levels of maternal antenatal cortisol were associated with greater cortisol response only among infants of less emotionally available mothers. All other markers of antenatal stress were not significantly associated with infant cortisol reactivity either independently or in interaction with maternal caregiving. CONCLUSIONS: Albeit preliminary, results provide the first evidence in humans that maternal sensitive caregiving may eliminate the association between antenatal maternal cortisol and infant cortisol regulation. En ligne : http://dx.doi.org/10.1111/jcpp.13532 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 [article] Maternal caregiving moderates the impact of antenatal maternal cortisol on infant stress regulation [Texte imprimé et/ou numérique] / Sarah NAZZARI, Auteur ; Richard M. PASCO FEARON, Auteur ; Frances RICE, Auteur ; Massimo MOLTENI, Auteur ; Alessandra FRIGERIO, Auteur . - p.871-880. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.871-880 Mots-clés : Adult  Anxiety  Depression/psychology  Depression, Postpartum  Female  Humans  Hydrocortisone/metabolism  Infant  Male  Mother-Child Relations/psychology  Mothers/psychology  Pregnancy  Saliva  Stress, Psychological/psychology  Cortisol  alpha-amylase  caregiving  inflammation  stress Index. décimale : PER Périodiques Résumé : BACKGROUND: Emerging evidence suggests that antenatal exposure to maternal stress signals affects the development of the infant stress response systems. Animal studies indicate that maternal sensitive caregiving can reverse some of these effects. However, the generalizability of these findings to humans is unknown. This study investigated the role of maternal caregiving in the association between multiple markers of maternal antenatal stress and infant stress regulation. METHODS: The sample consisted of 94 mother-infant (N=47 males, mean postnatal weeks=12; SD=1.84) dyads. Maternal levels of Interleukin-6, C-Reactive Protein (CRP), diurnal cortisol and alpha amylase, depressive and anxiety symptoms were assessed in late pregnancy (mean gestational age=34.76; SD=1.12), whereas postnatal symptomatology, caregiving, and infant cortisol response to the inoculation were evaluated at 3months. RESULTS: Hierarchical linear models (HLMs) showed a significant interaction between maternal antenatal cortisol, caregiving, and time on infant cortisol reactivity, while controlling for gender, maternal age, and postnatal depression. Specifically, higher levels of maternal antenatal cortisol were associated with greater cortisol response only among infants of less emotionally available mothers. All other markers of antenatal stress were not significantly associated with infant cortisol reactivity either independently or in interaction with maternal caregiving. CONCLUSIONS: Albeit preliminary, results provide the first evidence in humans that maternal sensitive caregiving may eliminate the association between antenatal maternal cortisol and infant cortisol regulation. En ligne : http://dx.doi.org/10.1111/jcpp.13532 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486

Obsessive-compulsive disorder in children and youth: neurocognitive function in clinic and community samples / Russell SCHACHAR in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.881-889 Titre : Obsessive-compulsive disorder in children and youth: neurocognitive function in clinic and community samples Type de document : Texte imprimé et/ou numérique Auteurs : Russell SCHACHAR, Auteur ; Annie DUPUIS, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Stelios GEORGIADES, Auteur ; Noam SORENI, Auteur ; Paul D. ARNOLD, Auteur ; Christie L. BURTON, Auteur ; Jennifer CROSBIE, Auteur Article en page(s) : p.881-889 Langues : Anglais (eng) Mots-clés : Adolescent  Attention  Child  Comorbidity  Humans  Obsessive-Compulsive Disorder/diagnosis  Phenotype  Reaction Time/physiology  Ocd  Stop-signal task  executive function  neurocognition Index. décimale : PER Périodiques Résumé : BACKGROUND: Neurocognitive impairments are common in OCD, although not well studied in children and youth with the disorder. METHOD: Using the stop-signal task (SST), we measured response inhibition (stop-signal reaction time-SSRT), sustained attention (reaction time variability-RTV), reaction time (RT), and performance monitoring (post-error slowing-PES) in OCD cases and controls from two samples of children and youth. A Clinic OCD group (n=171, aged 7-17years) was recruited from a specialty clinic after rigorous assessment. A typically developing (Clinic TD, n=157) group was enlisted through advertisement. A community OCD sample (Community OCD, n=147) and controls (Community TD n=13,832, aged 6-17 years) were recruited at a science museum. We also identified a community group with high OCD traits without an OCD diagnosis (Community High Trait; n=125). RESULTS: Clinic OCD participants had longer SSRT and greater RTV than Clinic TD. These effects were greater in younger OCD participants and, for SSRT, in those on medication for OCD. The Community OCD group did not differ from Controls but was similar to the Clinic OCD group in ADHD and ASD comorbidity and medication usage. The Community High Trait group had longer SSRT and atypical PES suggesting that symptom severity predicts neurocognitive function. No group differences were found in RT. CONCLUSIONS: In the largest study of neurocognitive performance in children with OCD to date, we found impaired response inhibition and sustained attention in OCD participants in comparison to typically developing peers. Performance was worse in younger OCD participants. In the community sample, participants with high OCD trait scores but no OCD diagnosis had impaired response inhibition and error processing, suggesting that OCD might be under-recognized. En ligne : http://dx.doi.org/10.1111/jcpp.13533 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 [article] Obsessive-compulsive disorder in children and youth: neurocognitive function in clinic and community samples [Texte imprimé et/ou numérique] / Russell SCHACHAR, Auteur ; Annie DUPUIS, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Stelios GEORGIADES, Auteur ; Noam SORENI, Auteur ; Paul D. ARNOLD, Auteur ; Christie L. BURTON, Auteur ; Jennifer CROSBIE, Auteur . - p.881-889. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.881-889 Mots-clés : Adolescent  Attention  Child  Comorbidity  Humans  Obsessive-Compulsive Disorder/diagnosis  Phenotype  Reaction Time/physiology  Ocd  Stop-signal task  executive function  neurocognition Index. décimale : PER Périodiques Résumé : BACKGROUND: Neurocognitive impairments are common in OCD, although not well studied in children and youth with the disorder. METHOD: Using the stop-signal task (SST), we measured response inhibition (stop-signal reaction time-SSRT), sustained attention (reaction time variability-RTV), reaction time (RT), and performance monitoring (post-error slowing-PES) in OCD cases and controls from two samples of children and youth. A Clinic OCD group (n=171, aged 7-17years) was recruited from a specialty clinic after rigorous assessment. A typically developing (Clinic TD, n=157) group was enlisted through advertisement. A community OCD sample (Community OCD, n=147) and controls (Community TD n=13,832, aged 6-17 years) were recruited at a science museum. We also identified a community group with high OCD traits without an OCD diagnosis (Community High Trait; n=125). RESULTS: Clinic OCD participants had longer SSRT and greater RTV than Clinic TD. These effects were greater in younger OCD participants and, for SSRT, in those on medication for OCD. The Community OCD group did not differ from Controls but was similar to the Clinic OCD group in ADHD and ASD comorbidity and medication usage. The Community High Trait group had longer SSRT and atypical PES suggesting that symptom severity predicts neurocognitive function. No group differences were found in RT. CONCLUSIONS: In the largest study of neurocognitive performance in children with OCD to date, we found impaired response inhibition and sustained attention in OCD participants in comparison to typically developing peers. Performance was worse in younger OCD participants. In the community sample, participants with high OCD trait scores but no OCD diagnosis had impaired response inhibition and error processing, suggesting that OCD might be under-recognized. En ligne : http://dx.doi.org/10.1111/jcpp.13533 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486

Shared familial risk factors between autism spectrum disorder and obesity - a register-based familial coaggregation cohort study / Richard AHLBERG in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.890-899 Titre : Shared familial risk factors between autism spectrum disorder and obesity - a register-based familial coaggregation cohort study Type de document : Texte imprimé et/ou numérique Auteurs : Richard AHLBERG, Auteur ; Miguel GARCIA-ARGIBAY, Auteur ; Tatja HIRVIKOSKI, Auteur ; Marcus BOMAN, Auteur ; Qi CHEN, Auteur ; Mark J. TAYLOR, Auteur ; Emma FRANS, Auteur ; Sven BÖLTE, Auteur ; Henrik LARSSON, Auteur Article en page(s) : p.890-899 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/etiology/genetics  Cohort Studies  Female  Genetic Predisposition to Disease  Humans  Intellectual Disability/complications  Male  Obesity/epidemiology/genetics  Registries  Risk Factors  Sweden/epidemiology  Autism  family factors  obesity Index. décimale : PER Périodiques Résumé : BACKGROUND: Meta-analyses suggest an association between autism spectrum disorder (ASD) and obesity, but the factors underlying this association remain unclear. This study investigated the association between ASD and obesity stratified on intellectual disability (ID). In addition, in order to gain insight into possible shared etiological factors, the potential role of shared familial liability was examined. METHOD: We studied a cohort of 3,141,696 individuals by linking several Swedish nationwide registers. We identified 35,461 individuals with ASD and 61,784 individuals with obesity. Logistic regression models were used to estimate the association between ASD and obesity separately by ID and sex and by adjusting for parental education, psychiatric comorbidity, and psychotropic medication. Potential shared familial etiologic factors were examined by comparing the risk of obesity in full siblings, maternal and paternal half-siblings, and full- and half-cousins of individuals with ASD to the risk of obesity in relatives of individuals without ASD. RESULTS: Individuals with ASD+ID (OR=3.76 [95% CI, 3.38-4.19]) and ASD-ID (OR=3.40 [95% CI, 3.23-3.58]) had an increased risk for obesity compared with individuals without ASD. The associations remained statistically significant when adjusting for parental education, psychiatric comorbidity, and medication. Sex-stratified analyses indicated a higher relative risk for males compared with females, with statistically significant interaction effects for ASD-ID, but not for ASD+ID in the fully adjusted model. First-degree relatives of individuals with ASD+ID and ASD-ID had an increased risk of obesity compared with first-degree relatives of individuals without ASD. The obesity risk was similar in second-degree relatives of individuals with ASD+ID but was lower for and ASD-ID. Full cousins of individuals with ASD+ID had a higher risk compared with half-cousins of individuals with ASD+ID). A similar difference in the obesity risk between full cousins and half-cousins was observed for ASD-ID. CONCLUSIONS: Individuals with ASD and their relatives are at increased risk for obesity. The risk might be somewhat higher for males than females. This warrants further studies examining potential common pleiotropic genetic factors and shared family-wide environmental factors for ASD and obesity. Such research might aid in identifying specific risks and underlying mechanisms in common between ASD and obesity. En ligne : http://dx.doi.org/10.1111/jcpp.13538 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 [article] Shared familial risk factors between autism spectrum disorder and obesity - a register-based familial coaggregation cohort study [Texte imprimé et/ou numérique] / Richard AHLBERG, Auteur ; Miguel GARCIA-ARGIBAY, Auteur ; Tatja HIRVIKOSKI, Auteur ; Marcus BOMAN, Auteur ; Qi CHEN, Auteur ; Mark J. TAYLOR, Auteur ; Emma FRANS, Auteur ; Sven BÖLTE, Auteur ; Henrik LARSSON, Auteur . - p.890-899. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.890-899 Mots-clés : Autism Spectrum Disorder/etiology/genetics  Cohort Studies  Female  Genetic Predisposition to Disease  Humans  Intellectual Disability/complications  Male  Obesity/epidemiology/genetics  Registries  Risk Factors  Sweden/epidemiology  Autism  family factors  obesity Index. décimale : PER Périodiques Résumé : BACKGROUND: Meta-analyses suggest an association between autism spectrum disorder (ASD) and obesity, but the factors underlying this association remain unclear. This study investigated the association between ASD and obesity stratified on intellectual disability (ID). In addition, in order to gain insight into possible shared etiological factors, the potential role of shared familial liability was examined. METHOD: We studied a cohort of 3,141,696 individuals by linking several Swedish nationwide registers. We identified 35,461 individuals with ASD and 61,784 individuals with obesity. Logistic regression models were used to estimate the association between ASD and obesity separately by ID and sex and by adjusting for parental education, psychiatric comorbidity, and psychotropic medication. Potential shared familial etiologic factors were examined by comparing the risk of obesity in full siblings, maternal and paternal half-siblings, and full- and half-cousins of individuals with ASD to the risk of obesity in relatives of individuals without ASD. RESULTS: Individuals with ASD+ID (OR=3.76 [95% CI, 3.38-4.19]) and ASD-ID (OR=3.40 [95% CI, 3.23-3.58]) had an increased risk for obesity compared with individuals without ASD. The associations remained statistically significant when adjusting for parental education, psychiatric comorbidity, and medication. Sex-stratified analyses indicated a higher relative risk for males compared with females, with statistically significant interaction effects for ASD-ID, but not for ASD+ID in the fully adjusted model. First-degree relatives of individuals with ASD+ID and ASD-ID had an increased risk of obesity compared with first-degree relatives of individuals without ASD. The obesity risk was similar in second-degree relatives of individuals with ASD+ID but was lower for and ASD-ID. Full cousins of individuals with ASD+ID had a higher risk compared with half-cousins of individuals with ASD+ID). A similar difference in the obesity risk between full cousins and half-cousins was observed for ASD-ID. CONCLUSIONS: Individuals with ASD and their relatives are at increased risk for obesity. The risk might be somewhat higher for males than females. This warrants further studies examining potential common pleiotropic genetic factors and shared family-wide environmental factors for ASD and obesity. Such research might aid in identifying specific risks and underlying mechanisms in common between ASD and obesity. En ligne : http://dx.doi.org/10.1111/jcpp.13538 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486

What time do you plan to sleep tonight? An intense longitudinal study of adolescent daily sleep self-regulation via planning and its associations with sleep opportunity / Svetlana MASKEVICH in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.900-911 Titre : What time do you plan to sleep tonight? An intense longitudinal study of adolescent daily sleep self-regulation via planning and its associations with sleep opportunity Type de document : Texte imprimé et/ou numérique Auteurs : Svetlana MASKEVICH, Auteur ; Lin SHEN, Auteur ; Sean P. A. DRUMMOND, Auteur ; Bei BEI, Auteur Article en page(s) : p.900-911 Langues : Anglais (eng) Mots-clés : Actigraphy  Adolescent  Female  Humans  Longitudinal Studies  Male  Schools  Self-Control  Sleep/physiology  Adolescents  planning  sleep restriction  sleep self-regulation  teenagers  unconstrained sleep Index. décimale : PER Périodiques Résumé : BACKGROUND: Most adolescents are sleep deprived on school days, yet how they self-regulate their sleep-wake behaviours is poorly understood. Using ecological momentary assessment, this intense longitudinal study explored patterns of adolescents' daily bedtime and risetime planning and execution, and whether these behaviours predicted sleep opportunity. METHODS: Every afternoon, for 2 school weeks and the subsequent 2 vacation weeks, 205 (54.1% female, 64.4% non-White) adolescents from year 10 to 12 (MÂ+SD(age) =16.9Â+0.9) reported their plans for bedtime (BT) that evening, and for risetimes (RT) the following day. Actual daily sleep was measured via actigraphy and sleep diary. RESULTS: Some adolescents never planned bedtime (school 19.5%, non-school 53.2%) or risetime (school 1.5%, non-school 24.4%). More adolescents planned consistently (â¥75% of days) on school (BT=29.9%, RT=61.3%) compared to non-school nights (BT=3.5%, RT=2.5%). On average, adolescents went to bed later than planned, with longer delays on non-school (71min) compared to school nights (46min). Of those who executed their plans within 15min, more did it consistently (â¥75% of days) on school (BT=40.9%, RT=67.7%) than on non-school nights/days (BT=29.7%, RT=58.6%). Mixed effects models utilizing daily data, controlling for sex, race, and study day, showed that bedtime planning predicted longer time in bed (TIB; p<.01) on school and shorter TIB on non-school nights (p<.01); and greater delay in actual (compared to planned) BT predicted shorter TIB (p<.001). CONCLUSIONS: Adolescents may require support during the transition from parent-controlled to autonomous sleep self-regulation. Bedtime planning on school nights and going to bed as planned are two modifiable sleep regulatory behaviours that are protective and potential therapeutic targets for increasing sleep opportunity in adolescents. En ligne : http://dx.doi.org/10.1111/jcpp.13540 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 [article] What time do you plan to sleep tonight? An intense longitudinal study of adolescent daily sleep self-regulation via planning and its associations with sleep opportunity [Texte imprimé et/ou numérique] / Svetlana MASKEVICH, Auteur ; Lin SHEN, Auteur ; Sean P. A. DRUMMOND, Auteur ; Bei BEI, Auteur . - p.900-911. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.900-911 Mots-clés : Actigraphy  Adolescent  Female  Humans  Longitudinal Studies  Male  Schools  Self-Control  Sleep/physiology  Adolescents  planning  sleep restriction  sleep self-regulation  teenagers  unconstrained sleep Index. décimale : PER Périodiques Résumé : BACKGROUND: Most adolescents are sleep deprived on school days, yet how they self-regulate their sleep-wake behaviours is poorly understood. Using ecological momentary assessment, this intense longitudinal study explored patterns of adolescents' daily bedtime and risetime planning and execution, and whether these behaviours predicted sleep opportunity. METHODS: Every afternoon, for 2 school weeks and the subsequent 2 vacation weeks, 205 (54.1% female, 64.4% non-White) adolescents from year 10 to 12 (MÂ+SD(age) =16.9Â+0.9) reported their plans for bedtime (BT) that evening, and for risetimes (RT) the following day. Actual daily sleep was measured via actigraphy and sleep diary. RESULTS: Some adolescents never planned bedtime (school 19.5%, non-school 53.2%) or risetime (school 1.5%, non-school 24.4%). More adolescents planned consistently (â¥75% of days) on school (BT=29.9%, RT=61.3%) compared to non-school nights (BT=3.5%, RT=2.5%). On average, adolescents went to bed later than planned, with longer delays on non-school (71min) compared to school nights (46min). Of those who executed their plans within 15min, more did it consistently (â¥75% of days) on school (BT=40.9%, RT=67.7%) than on non-school nights/days (BT=29.7%, RT=58.6%). Mixed effects models utilizing daily data, controlling for sex, race, and study day, showed that bedtime planning predicted longer time in bed (TIB; p<.01) on school and shorter TIB on non-school nights (p<.01); and greater delay in actual (compared to planned) BT predicted shorter TIB (p<.001). CONCLUSIONS: Adolescents may require support during the transition from parent-controlled to autonomous sleep self-regulation. Bedtime planning on school nights and going to bed as planned are two modifiable sleep regulatory behaviours that are protective and potential therapeutic targets for increasing sleep opportunity in adolescents. En ligne : http://dx.doi.org/10.1111/jcpp.13540 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486

Parenting moderates the etiology of callous-unemotional traits in middle childhood / Rachel C. TOMLINSON in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.912-920 Titre : Parenting moderates the etiology of callous-unemotional traits in middle childhood Type de document : Texte imprimé et/ou numérique Auteurs : Rachel C. TOMLINSON, Auteur ; Luke W. HYDE, Auteur ; Hailey L. DOTTERER, Auteur ; Kelly L. KLUMP, Auteur ; S Alexandra BURT, Auteur Article en page(s) : p.912-920 Langues : Anglais (eng) Mots-clés : Adolescent  Antisocial Personality Disorder/genetics/psychology  Child  Conduct Disorder/genetics/psychology  Copper  Emotions  Empathy  Humans  Parenting/psychology  Genotype×Environment (G×E) interaction  Harshness  twin model  warmth Index. décimale : PER Périodiques Résumé : BACKGROUND: Callous-unemotional (CU) traits are associated with chronic and escalating trajectories of antisocial behavior. Extant etiologic studies suggest that heritability estimates for CU traits vary substantially, while also pointing to an environmental association between parenting and CU traits. METHODS: We used twin modeling to estimate additive genetic (A), shared environmental (C), and nonshared environmental (E) influences on CU traits, measured with the Inventory of Callous-Unemotional Traits (ICU) and its subscales. Our sample included 600 twin pairs (age 6-11, 230 monozygotic) from neighborhoods with above-average levels of family poverty, a risk factor for antisocial behavior. We examined the extent to which correlations between parenting, measured via parent and child report on the Parental Environment Questionnaire, and CU traits reflected genetic versus environmental factors. Then, we tested whether parenting moderated the heritability of CU traits. RESULTS: In the context of lower-income neighborhoods, CU traits were moderately to highly heritable (A=54%) with similar moderate-to-high nonshared environmental influences (E=46%). Bivariate models revealed that associations between CU traits and warm parenting were genetic (rA=.22) and environmental (rE=.19) in origin, whereas associations between CU traits and harsh parenting were largely genetic in origin (rA=.70). The heritability of CU traits decreased with increasing parental warmth and decreasing harshness. CONCLUSIONS: Callous-unemotional traits are both genetic and environmental in origin during middle childhood, but genetic influences are moderated by parenting quality. Parenting may be an important target for interventions, particularly among youth with greater genetic risk. En ligne : http://dx.doi.org/10.1111/jcpp.13542 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 [article] Parenting moderates the etiology of callous-unemotional traits in middle childhood [Texte imprimé et/ou numérique] / Rachel C. TOMLINSON, Auteur ; Luke W. HYDE, Auteur ; Hailey L. DOTTERER, Auteur ; Kelly L. KLUMP, Auteur ; S Alexandra BURT, Auteur . - p.912-920. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.912-920 Mots-clés : Adolescent  Antisocial Personality Disorder/genetics/psychology  Child  Conduct Disorder/genetics/psychology  Copper  Emotions  Empathy  Humans  Parenting/psychology  Genotype×Environment (G×E) interaction  Harshness  twin model  warmth Index. décimale : PER Périodiques Résumé : BACKGROUND: Callous-unemotional (CU) traits are associated with chronic and escalating trajectories of antisocial behavior. Extant etiologic studies suggest that heritability estimates for CU traits vary substantially, while also pointing to an environmental association between parenting and CU traits. METHODS: We used twin modeling to estimate additive genetic (A), shared environmental (C), and nonshared environmental (E) influences on CU traits, measured with the Inventory of Callous-Unemotional Traits (ICU) and its subscales. Our sample included 600 twin pairs (age 6-11, 230 monozygotic) from neighborhoods with above-average levels of family poverty, a risk factor for antisocial behavior. We examined the extent to which correlations between parenting, measured via parent and child report on the Parental Environment Questionnaire, and CU traits reflected genetic versus environmental factors. Then, we tested whether parenting moderated the heritability of CU traits. RESULTS: In the context of lower-income neighborhoods, CU traits were moderately to highly heritable (A=54%) with similar moderate-to-high nonshared environmental influences (E=46%). Bivariate models revealed that associations between CU traits and warm parenting were genetic (rA=.22) and environmental (rE=.19) in origin, whereas associations between CU traits and harsh parenting were largely genetic in origin (rA=.70). The heritability of CU traits decreased with increasing parental warmth and decreasing harshness. CONCLUSIONS: Callous-unemotional traits are both genetic and environmental in origin during middle childhood, but genetic influences are moderated by parenting quality. Parenting may be an important target for interventions, particularly among youth with greater genetic risk. En ligne : http://dx.doi.org/10.1111/jcpp.13542 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486

Adverse clinical outcomes among youths with nonsuicidal self-injury and suicide attempts: a longitudinal cohort study / Johan BJUREBERG in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.921-928 Titre : Adverse clinical outcomes among youths with nonsuicidal self-injury and suicide attempts: a longitudinal cohort study Type de document : Texte imprimé et/ou numérique Auteurs : Johan BJUREBERG, Auteur ; Ralf KUJA-HALKOLA, Auteur ; Anna OHLIS, Auteur ; Paul LICHTENSTEIN, Auteur ; Brian M. D'ONOFRIO, Auteur ; Clara HELLNER, Auteur ; Martin CEDERLOF, Auteur Article en page(s) : p.921-928 Langues : Anglais (eng) Mots-clés : Adolescent  Cohort Studies  Humans  Longitudinal Studies  Risk Factors  Self-Injurious Behavior/epidemiology/psychology/therapy  Substance-Related Disorders/epidemiology/therapy  Suicidal Ideation  Suicide, Attempted/psychology  Self-injury  self-harm  suicidal behaviour Index. décimale : PER Périodiques Résumé : BACKGROUND: More knowledge about risks of clinical outcomes associated with nonsuicidal self-injury (NSSI) and suicide attempts (SAs) is needed to inform risk assessment and intervention. METHODS: Longitudinal cohort study based on 1,855 youths was clinically assessed for NSSI and SA, and followed up (from December, 2011 to December 2013) for the outcomes; diagnosed self-injury, alcohol/substance use disorder, and psychiatric inpatient care data derived from Swedish registers. Hazard ratios (HRs) and 95% confidence intervals (CIs) of the outcomes were estimated with Cox regressions, and additionally adjusted for the potential effect of sex and the number of clinical assessments. NSSI and SA were treated as time-varying covariates. RESULTS: Youths with NSSI had elevated risks of all outcomes, compared with youths without NSSI or SA; the HR was 2.3, 95% confidence interval [1.6, 3.4] for self-injury, 1.4 [0.9, 2.1] for alcohol/substance use disorder, and 1.3 [1.0, 1.7] for psychiatric inpatient care. Youths with SA displayed higher risks for the outcomes than the NSSI group; the HR was 5.5 [2.4, 12.6] for self-injury, 2.0 [0.9, 4.4] for alcohol/substance use disorder, and 2.6 [1.5, 4.5] for psychiatric inpatient care. Youths with both NSSI and SA showed similar risks as youths with SA; HR 4.1 [2.0, 8.3] for self-injury, 2.0 [1.1, 4.1] for alcohol/substance use disorder, but a higher risk of psychiatric inpatient care; HR 5.0 [3.1, 7.9]. All results remained virtually unchanged in the adjusted analyses. CONCLUSIONS: Youths with NSSI and/or SA had higher risks for subsequent adverse clinical outcomes. These excess risks were more pronounced among youths with SA and youths with both NSSI and SA, and the risk for psychiatric inpatient care was particularly high in youths with both NSSI and SA. Our findings suggest that early interventions for youths with NSSI or SA should not exclusively focus on suicide prevention, but also consider the risk of subsequent alcohol/substance use disorder. En ligne : http://dx.doi.org/10.1111/jcpp.13544 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 [article] Adverse clinical outcomes among youths with nonsuicidal self-injury and suicide attempts: a longitudinal cohort study [Texte imprimé et/ou numérique] / Johan BJUREBERG, Auteur ; Ralf KUJA-HALKOLA, Auteur ; Anna OHLIS, Auteur ; Paul LICHTENSTEIN, Auteur ; Brian M. D'ONOFRIO, Auteur ; Clara HELLNER, Auteur ; Martin CEDERLOF, Auteur . - p.921-928. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.921-928 Mots-clés : Adolescent  Cohort Studies  Humans  Longitudinal Studies  Risk Factors  Self-Injurious Behavior/epidemiology/psychology/therapy  Substance-Related Disorders/epidemiology/therapy  Suicidal Ideation  Suicide, Attempted/psychology  Self-injury  self-harm  suicidal behaviour Index. décimale : PER Périodiques Résumé : BACKGROUND: More knowledge about risks of clinical outcomes associated with nonsuicidal self-injury (NSSI) and suicide attempts (SAs) is needed to inform risk assessment and intervention. METHODS: Longitudinal cohort study based on 1,855 youths was clinically assessed for NSSI and SA, and followed up (from December, 2011 to December 2013) for the outcomes; diagnosed self-injury, alcohol/substance use disorder, and psychiatric inpatient care data derived from Swedish registers. Hazard ratios (HRs) and 95% confidence intervals (CIs) of the outcomes were estimated with Cox regressions, and additionally adjusted for the potential effect of sex and the number of clinical assessments. NSSI and SA were treated as time-varying covariates. RESULTS: Youths with NSSI had elevated risks of all outcomes, compared with youths without NSSI or SA; the HR was 2.3, 95% confidence interval [1.6, 3.4] for self-injury, 1.4 [0.9, 2.1] for alcohol/substance use disorder, and 1.3 [1.0, 1.7] for psychiatric inpatient care. Youths with SA displayed higher risks for the outcomes than the NSSI group; the HR was 5.5 [2.4, 12.6] for self-injury, 2.0 [0.9, 4.4] for alcohol/substance use disorder, and 2.6 [1.5, 4.5] for psychiatric inpatient care. Youths with both NSSI and SA showed similar risks as youths with SA; HR 4.1 [2.0, 8.3] for self-injury, 2.0 [1.1, 4.1] for alcohol/substance use disorder, but a higher risk of psychiatric inpatient care; HR 5.0 [3.1, 7.9]. All results remained virtually unchanged in the adjusted analyses. CONCLUSIONS: Youths with NSSI and/or SA had higher risks for subsequent adverse clinical outcomes. These excess risks were more pronounced among youths with SA and youths with both NSSI and SA, and the risk for psychiatric inpatient care was particularly high in youths with both NSSI and SA. Our findings suggest that early interventions for youths with NSSI or SA should not exclusively focus on suicide prevention, but also consider the risk of subsequent alcohol/substance use disorder. En ligne : http://dx.doi.org/10.1111/jcpp.13544 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486

Development of a risk calculator to predict attention-deficit/hyperactivity disorder in very preterm/very low birth weight newborns / Adelar Pedro FRANZ in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.929-938 Titre : Development of a risk calculator to predict attention-deficit/hyperactivity disorder in very preterm/very low birth weight newborns Type de document : Texte imprimé et/ou numérique Auteurs : Adelar Pedro FRANZ, Auteur ; Arthur CAYE, Auteur ; Barbara Calil LACERDA, Auteur ; Flavia WAGNER, Auteur ; Rita C. SILVEIRA, Auteur ; Renato Soibelmann PROCIANOY, Auteur ; Carlos Renato MOREIRA-MAIA, Auteur ; Luis Augusto ROHDE, Auteur Article en page(s) : p.929-938 Langues : Anglais (eng) Mots-clés : Attention Deficit Disorder with Hyperactivity/diagnosis/epidemiology  Child  Gestational Age  Humans  Infant  Infant, Extremely Premature  Infant, Newborn  Infant, Very Low Birth Weight/psychology  Retrospective Studies  Prematurity  attention-deficit/hyperactivity disorder  low birth weight  prediction Index. décimale : PER Périodiques Résumé : BACKGROUND: Very preterm/very low birth weight (VP/VLBW) newborns can have lifelong morbidities, as attention-deficit/hyperactivity disorder (ADHD). Clinicians have no markers to discriminate which among those individuals will develop later ADHD, based only on the clinical presentation at birth. Our aim was to develop an individualized risk calculator for ADHD in VP/VLBW newborns. METHODS: This retrospective prognostic study included a consecutive sample of all VP/VLBW children (gestational age<32weeks and/or birth weight<1.5kg) born between 2010 and 2012 from a clinical cohort in a Brazilian tertiary care hospital. Children were clinically assessed at 6years of age for ADHD using the Schedule for Affective Disorders and Schizophrenia for School-Age Children (K-SADS). The least absolute shrinkage and selection operator (LASSO) method was used for model-building. RESULTS: Ninety-six VP/VLBW children were assessed at 6years of age (92% follow-up), of whom 32 (33%) were diagnosed with ADHD. The area under the ROC curve (AUC) for ADHD prediction based on seven parameters (late-onset sepsis confirmed by blood culture, necrotizing enterocolitis, neonatal seizures, periventricular leukomalacia, respiratory distress syndrome, length of hospital stay, and number of maternal ADHD symptoms) was .875 (CI, 0.800-0.942, p<.001; AUC corrected for optimism with bootstrapping: .806), a performance that is comparable to other medical risk calculators. Compared to approaches that would offer early intervention to all, or intervention to none, the risk calculator will be more useful in selecting VP/VLBW newborns, with statistically significant net benefits at cost:benefits of around 1:2 to around 10:6 (range of ADHD risk thresholds of 32%-62%, respectively). It also showed specificity for ADHD compared to other prevalent child psychopathologies. CONCLUSIONS: The risk calculator showed good performance for early identification of VP/VLBW newborns at high risk of future ADHD diagnosis. External validity in population-based samples is needed to extend clinical usefulness. En ligne : http://dx.doi.org/10.1111/jcpp.13546 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 [article] Development of a risk calculator to predict attention-deficit/hyperactivity disorder in very preterm/very low birth weight newborns [Texte imprimé et/ou numérique] / Adelar Pedro FRANZ, Auteur ; Arthur CAYE, Auteur ; Barbara Calil LACERDA, Auteur ; Flavia WAGNER, Auteur ; Rita C. SILVEIRA, Auteur ; Renato Soibelmann PROCIANOY, Auteur ; Carlos Renato MOREIRA-MAIA, Auteur ; Luis Augusto ROHDE, Auteur . - p.929-938. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.929-938 Mots-clés : Attention Deficit Disorder with Hyperactivity/diagnosis/epidemiology  Child  Gestational Age  Humans  Infant  Infant, Extremely Premature  Infant, Newborn  Infant, Very Low Birth Weight/psychology  Retrospective Studies  Prematurity  attention-deficit/hyperactivity disorder  low birth weight  prediction Index. décimale : PER Périodiques Résumé : BACKGROUND: Very preterm/very low birth weight (VP/VLBW) newborns can have lifelong morbidities, as attention-deficit/hyperactivity disorder (ADHD). Clinicians have no markers to discriminate which among those individuals will develop later ADHD, based only on the clinical presentation at birth. Our aim was to develop an individualized risk calculator for ADHD in VP/VLBW newborns. METHODS: This retrospective prognostic study included a consecutive sample of all VP/VLBW children (gestational age<32weeks and/or birth weight<1.5kg) born between 2010 and 2012 from a clinical cohort in a Brazilian tertiary care hospital. Children were clinically assessed at 6years of age for ADHD using the Schedule for Affective Disorders and Schizophrenia for School-Age Children (K-SADS). The least absolute shrinkage and selection operator (LASSO) method was used for model-building. RESULTS: Ninety-six VP/VLBW children were assessed at 6years of age (92% follow-up), of whom 32 (33%) were diagnosed with ADHD. The area under the ROC curve (AUC) for ADHD prediction based on seven parameters (late-onset sepsis confirmed by blood culture, necrotizing enterocolitis, neonatal seizures, periventricular leukomalacia, respiratory distress syndrome, length of hospital stay, and number of maternal ADHD symptoms) was .875 (CI, 0.800-0.942, p<.001; AUC corrected for optimism with bootstrapping: .806), a performance that is comparable to other medical risk calculators. Compared to approaches that would offer early intervention to all, or intervention to none, the risk calculator will be more useful in selecting VP/VLBW newborns, with statistically significant net benefits at cost:benefits of around 1:2 to around 10:6 (range of ADHD risk thresholds of 32%-62%, respectively). It also showed specificity for ADHD compared to other prevalent child psychopathologies. CONCLUSIONS: The risk calculator showed good performance for early identification of VP/VLBW newborns at high risk of future ADHD diagnosis. External validity in population-based samples is needed to extend clinical usefulness. En ligne : http://dx.doi.org/10.1111/jcpp.13546 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486

Clinical utility of family history of depression for prognosis of adolescent depression severity and duration assessed with predictive modeling / Lisa S. GORHAM in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.939-947 Titre : Clinical utility of family history of depression for prognosis of adolescent depression severity and duration assessed with predictive modeling Type de document : Texte imprimé et/ou numérique Auteurs : Lisa S. GORHAM, Auteur ; Neda SADEGHI, Auteur ; Lillian EISNER, Auteur ; Jeremy TAIGMAN, Auteur ; Katherine HAYNES, Auteur ; Karen QI, Auteur ; Christopher C. CAMP, Auteur ; Payton FORS, Auteur ; Diana RODRIGUEZ, Auteur ; Jerry MCGUIRE, Auteur ; Erin GARTH, Auteur ; Chana ENGEL, Auteur ; Mollie DAVIS, Auteur ; Kenneth TOWBIN, Auteur ; Argyris STRINGARIS, Auteur ; Dylan M. NIELSON, Auteur Article en page(s) : p.939-947 Langues : Anglais (eng) Mots-clés : Depression/psychology  Humans  Longitudinal Studies  Prognosis  Risk Factors  Depression  adolescence  family history Index. décimale : PER Périodiques Résumé : BACKGROUND: Family history of depression (FHD) is a known risk factor for the new onset of depression. However, it is unclear if FHD is clinically useful for prognosis in adolescents with current, ongoing, or past depression. This preregistered study uses a longitudinal, multi-informant design to examine whether a child's FHD adds information about future depressive episodes and depression severity applying state-of-the-art predictive out-of-sample methodology. METHODS: We examined data in adolescents with current or past depression (age 11-17years) from the National Institute of Mental Health Characterization and Treatment of Adolescent Depression (CAT-D) study. We asked whether a history of depression in a first-degree relative was predictive of depressive episode duration (72 participants) and future depressive symptom severity in probands (129 participants, 1,439 total assessments). RESULTS: Family history of depression, while statistically associated with time spent depressed, did not improve predictions of time spent depressed, nor did it improve models of change in depression severity measured by self- or parent-report. CONCLUSIONS: Family history of depression does not improve the prediction of the course of depression in adolescents already diagnosed with depression. The difference between statistical association and predictive models highlights the importance of assessing predictive performance when evaluating questions of clinical utility. En ligne : http://dx.doi.org/10.1111/jcpp.13547 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 [article] Clinical utility of family history of depression for prognosis of adolescent depression severity and duration assessed with predictive modeling [Texte imprimé et/ou numérique] / Lisa S. GORHAM, Auteur ; Neda SADEGHI, Auteur ; Lillian EISNER, Auteur ; Jeremy TAIGMAN, Auteur ; Katherine HAYNES, Auteur ; Karen QI, Auteur ; Christopher C. CAMP, Auteur ; Payton FORS, Auteur ; Diana RODRIGUEZ, Auteur ; Jerry MCGUIRE, Auteur ; Erin GARTH, Auteur ; Chana ENGEL, Auteur ; Mollie DAVIS, Auteur ; Kenneth TOWBIN, Auteur ; Argyris STRINGARIS, Auteur ; Dylan M. NIELSON, Auteur . - p.939-947. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.939-947 Mots-clés : Depression/psychology  Humans  Longitudinal Studies  Prognosis  Risk Factors  Depression  adolescence  family history Index. décimale : PER Périodiques Résumé : BACKGROUND: Family history of depression (FHD) is a known risk factor for the new onset of depression. However, it is unclear if FHD is clinically useful for prognosis in adolescents with current, ongoing, or past depression. This preregistered study uses a longitudinal, multi-informant design to examine whether a child's FHD adds information about future depressive episodes and depression severity applying state-of-the-art predictive out-of-sample methodology. METHODS: We examined data in adolescents with current or past depression (age 11-17years) from the National Institute of Mental Health Characterization and Treatment of Adolescent Depression (CAT-D) study. We asked whether a history of depression in a first-degree relative was predictive of depressive episode duration (72 participants) and future depressive symptom severity in probands (129 participants, 1,439 total assessments). RESULTS: Family history of depression, while statistically associated with time spent depressed, did not improve predictions of time spent depressed, nor did it improve models of change in depression severity measured by self- or parent-report. CONCLUSIONS: Family history of depression does not improve the prediction of the course of depression in adolescents already diagnosed with depression. The difference between statistical association and predictive models highlights the importance of assessing predictive performance when evaluating questions of clinical utility. En ligne : http://dx.doi.org/10.1111/jcpp.13547 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486

Polygenic risks for joint developmental trajectories of internalizing and externalizing problems: findings from the ALSPAC cohort / Lydia Gabriela SPEYER in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.948-956 Titre : Polygenic risks for joint developmental trajectories of internalizing and externalizing problems: findings from the ALSPAC cohort Type de document : Texte imprimé et/ou numérique Auteurs : Lydia Gabriela SPEYER, Auteur ; Samuel NEAVES, Auteur ; Hildigunnur Anna HALL, Auteur ; Gibran HEMANI, Auteur ; Michael Vincent LOMBARDO, Auteur ; Aja Louise MURRAY, Auteur ; Bonnie AUYEUNG, Auteur ; Michelle LUCIANO, Auteur Article en page(s) : p.948-956 Langues : Anglais (eng) Mots-clés : Adolescent  Child  Child, Preschool  Female  Humans  Longitudinal Studies  Male  Mothers  Multifactorial Inheritance  Pregnancy  Risk Factors  Smoking  Alspac  Joint mental health trajectories  externalizing  internalizing  polygenic risk Index. décimale : PER Périodiques Résumé : BACKGROUND: Joint developmental trajectories of internalizing and externalizing problems show considerable heterogeneity; however, this can be parsed into a small number of meaningful subgroups. Doing so offered insights into risk factors that lead to different patterns of internalizing/externalizing trajectories. However, despite both domains of problems showing strong heritability, no study has yet considered genetic risks as predictors of joint internalizing/externalizing problem trajectories. METHODS: Using parallel process latent class growth analysis, we estimated joint developmental trajectories of internalizing and externalizing difficulties assessed across ages 4 to 16 using the Strengths and Difficulties Questionnaire. Multinomial logistic regression was used to evaluate a range of demographic, perinatal, maternal mental health, and child and maternal polygenic predictors of group membership. Participants included 11,049 children taking part in the Avon Longitudinal Study of Parents and Children. Polygenic data were available for 7,127 children and 6,836 mothers. RESULTS: A 5-class model was judged optimal: Unaffected, Moderate Externalizing Symptoms, High Externalizing Symptoms, Moderate Internalizing and Externalizing Symptoms and High Internalizing and Externalizing Symptoms. Male sex, lower maternal age, maternal mental health problems, maternal smoking during pregnancy, higher child polygenic risk scores for ADHD and lower polygenic scores for IQ distinguished affected classes from the unaffected class. CONCLUSIONS: While affected classes could be relatively well separated from the unaffected class, phenotypic and polygenic predictors were limited in their ability to distinguish between different affected classes. Results thus add to existing evidence that internalizing and externalizing problems have mostly shared risk factors. En ligne : http://dx.doi.org/10.1111/jcpp.13549 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 [article] Polygenic risks for joint developmental trajectories of internalizing and externalizing problems: findings from the ALSPAC cohort [Texte imprimé et/ou numérique] / Lydia Gabriela SPEYER, Auteur ; Samuel NEAVES, Auteur ; Hildigunnur Anna HALL, Auteur ; Gibran HEMANI, Auteur ; Michael Vincent LOMBARDO, Auteur ; Aja Louise MURRAY, Auteur ; Bonnie AUYEUNG, Auteur ; Michelle LUCIANO, Auteur . - p.948-956. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.948-956 Mots-clés : Adolescent  Child  Child, Preschool  Female  Humans  Longitudinal Studies  Male  Mothers  Multifactorial Inheritance  Pregnancy  Risk Factors  Smoking  Alspac  Joint mental health trajectories  externalizing  internalizing  polygenic risk Index. décimale : PER Périodiques Résumé : BACKGROUND: Joint developmental trajectories of internalizing and externalizing problems show considerable heterogeneity; however, this can be parsed into a small number of meaningful subgroups. Doing so offered insights into risk factors that lead to different patterns of internalizing/externalizing trajectories. However, despite both domains of problems showing strong heritability, no study has yet considered genetic risks as predictors of joint internalizing/externalizing problem trajectories. METHODS: Using parallel process latent class growth analysis, we estimated joint developmental trajectories of internalizing and externalizing difficulties assessed across ages 4 to 16 using the Strengths and Difficulties Questionnaire. Multinomial logistic regression was used to evaluate a range of demographic, perinatal, maternal mental health, and child and maternal polygenic predictors of group membership. Participants included 11,049 children taking part in the Avon Longitudinal Study of Parents and Children. Polygenic data were available for 7,127 children and 6,836 mothers. RESULTS: A 5-class model was judged optimal: Unaffected, Moderate Externalizing Symptoms, High Externalizing Symptoms, Moderate Internalizing and Externalizing Symptoms and High Internalizing and Externalizing Symptoms. Male sex, lower maternal age, maternal mental health problems, maternal smoking during pregnancy, higher child polygenic risk scores for ADHD and lower polygenic scores for IQ distinguished affected classes from the unaffected class. CONCLUSIONS: While affected classes could be relatively well separated from the unaffected class, phenotypic and polygenic predictors were limited in their ability to distinguish between different affected classes. Results thus add to existing evidence that internalizing and externalizing problems have mostly shared risk factors. En ligne : http://dx.doi.org/10.1111/jcpp.13549 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486

Editorial Perspective: Speaking up for developmental language disorder - the top 10 priorities for research / Amit A. KULKARNI in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.957-960 Titre : Editorial Perspective: Speaking up for developmental language disorder - the top 10 priorities for research Type de document : Texte imprimé et/ou numérique Auteurs : Amit A. KULKARNI, Auteur ; Katie E. CHADD, Auteur ; Sarah B. LAMBERT, Auteur ; Gill EARL, Auteur ; Lauren M. LONGHURST, Auteur ; Cristina MCKEAN, Auteur ; Charles HULME, Auteur ; Karla K. MCGREGOR, Auteur ; Anna CUNNIFF, Auteur ; Emma PAGNAMENTA, Auteur ; Victoria JOFFE, Auteur ; Susan E. EBBELS, Auteur ; Sai BANGERA, Auteur ; Josephine WALLINGER, Auteur ; Courtenay F. NORBURY, Auteur Article en page(s) : p.957-960 Langues : Anglais (eng) Mots-clés : Adolescent  Child  Humans  Language Development Disorders/epidemiology/therapy Index. décimale : PER Périodiques Résumé : Developmental language disorder (DLD) is one of the most common neurodevelopmental conditions, yet is chronically underserved, with far fewer children receiving clinical services than expected from prevalence estimates, and very little research attention relative to other neurodevelopmental conditions of similar prevalence and severity. This editorial describes a research priority-setting exercise undertaken by the Royal College of Speech and Language Therapists, which aims to redress this imbalance. From consultations with researchers, practitioners and individuals with lived experience, 10 research priorities emerge. Our goal is to share these priorities with the wider research community, to raise awareness and encourage research collaboration to improve outcomes for young people with DLD. En ligne : http://dx.doi.org/10.1111/jcpp.13592 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486 [article] Editorial Perspective: Speaking up for developmental language disorder - the top 10 priorities for research [Texte imprimé et/ou numérique] / Amit A. KULKARNI, Auteur ; Katie E. CHADD, Auteur ; Sarah B. LAMBERT, Auteur ; Gill EARL, Auteur ; Lauren M. LONGHURST, Auteur ; Cristina MCKEAN, Auteur ; Charles HULME, Auteur ; Karla K. MCGREGOR, Auteur ; Anna CUNNIFF, Auteur ; Emma PAGNAMENTA, Auteur ; Victoria JOFFE, Auteur ; Susan E. EBBELS, Auteur ; Sai BANGERA, Auteur ; Josephine WALLINGER, Auteur ; Courtenay F. NORBURY, Auteur . - p.957-960. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.957-960 Mots-clés : Adolescent  Child  Humans  Language Development Disorders/epidemiology/therapy Index. décimale : PER Périodiques Résumé : Developmental language disorder (DLD) is one of the most common neurodevelopmental conditions, yet is chronically underserved, with far fewer children receiving clinical services than expected from prevalence estimates, and very little research attention relative to other neurodevelopmental conditions of similar prevalence and severity. This editorial describes a research priority-setting exercise undertaken by the Royal College of Speech and Language Therapists, which aims to redress this imbalance. From consultations with researchers, practitioners and individuals with lived experience, 10 research priorities emerge. Our goal is to share these priorities with the wider research community, to raise awareness and encourage research collaboration to improve outcomes for young people with DLD. En ligne : http://dx.doi.org/10.1111/jcpp.13592 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486